[ { "uniprot_canonical_ac": "A0ABI0NTH4-1", "uniprot_ac": "A0ABI0NTH4", "uniprot_id": "A0ABI0NTH4_BOVIN", "mass": { "chemical_mass": 34619.0, "monoisotopic_mass": 34619.0 }, "refseq": {}, "gene_names": [ { "name": "PCTP", "type": "recommended", "evidence": [ { "id": "A0ABI0NTH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4" } ] } ], "protein_names": [ { "name": "Phosphatidylcholine transfer protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NTH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4/entry#names_and_taxonomy" } ] }, { "name": "START domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "A0ABI0NTH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4/entry#names_and_taxonomy" } ] }, { "name": "StAR-related lipid transfer protein 2", "type": "synonym", "evidence": [ { "id": "A0ABI0NTH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PCTP", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000018706", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018706", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08910", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08910", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LK81", "url": "https://www.orthodb.org/?gene=A0A3Q1LK81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19308:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19308:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01852", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01852", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LK81", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LK81-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKU5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKU5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z5A6", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z5A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z5A6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z5A6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTH4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6P0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6P0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6P0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6P0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPGAGAFSEEQFREACAELQRPALSGAAWELLVETQGISVYRLLDQQTGLYAYKVFGVLEDCLPDLLADVYMDLAYRKQWDQYVKELYEKECSGETVVYWQVKYPFPMSNRDYVYVRQRQELDFEGQKVHVILAQSTSEPQFPEKSGVIRVKHYKQRLAIQSDGKRGSKVFMYYFDNPGGQIPSWVINWAAKVRPQEARWVVCLTAVYLACGAVSLKRCAISGLMMLFYETAWLMDYVRSVVANTQDRGWDKRQTLEGMPAPPALHQDPSRITFQNLPNSSLFLVGTRVPGTLYLLMEELV", "length": 302, "header": "tr|A0ABI0NTH4-1|A0ABI0NTH4_BOVIN Isoform 1 of Phosphatidylcholine transfer protein OS=Bos taurus OX=9913 GN=PCTP PE=4 SV=1 CANONICAL=A0ABI0NTH4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LK81-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4/entry#A0A3Q1LK81-1", "sequence": { "sequence": "MDPGAGAFSEEQFREACAELQRPALSGAAWELLVETQGISVYRLLDQQTGLYAYKVFGVLEDCLPDLLADVYMDLAYRKQWDQYVKELYEKECSGETVVYWQVKYPFPMSNRDYVYVRQRQELDFEGQKVHVILAQSTSEPQFPEKSGVIRVKHYKQRLAIQSDGKRGSKASEETVGAGVPCSHLRTWSGCGLEAEAKSKFSCDVC", "length": 206, "header": "tr|A0A3Q1LK81-1|A0ABI0NTH4_BOVIN Computationally mapped isoform of Phosphatidylcholine transfer protein OS=Bos taurus OX=9913 GN=PCTP PE=4 SV=2 CANONICAL=A0ABI0NTH4-1" }, "locus": { "chromosome": "19", "start_pos": 6254277, "end_pos": 6232335, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069906.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069906.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056915.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056915.2" } ] } }, { "isoform_ac": "A0AAA9SKU5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4/entry#A0AAA9SKU5-1", "sequence": { "sequence": "MDPGAGAFSEEQFREACAELQRPALSGAAWELLVETQGISVYRLLDQQTGLYAYKVFGVLEDCLPDLLADVYMDLAYRKQWDQYVKELYEKECSGETVVYWQVKYPFPMSNRDYVYVRQRQELDFEGQKVHVILAQSTSEPQFPEKSGVIRVKHYKQRLAIQSDGKRGSKVFMYYFDNPGGQIPSWVINWAAKRELKETPPPPPKGPQKQKQLDLDTC", "length": 218, "header": "tr|A0AAA9SKU5-1|A0ABI0NTH4_BOVIN Computationally mapped isoform of Phosphatidylcholine transfer protein OS=Bos taurus OX=9913 GN=PCTP PE=4 SV=1 CANONICAL=A0ABI0NTH4-1" }, "locus": { "chromosome": "19", "start_pos": 6262158, "end_pos": 6232335, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104773.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104773.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083252.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083252.1" } ] } }, { "isoform_ac": "A0AAF6Z5A6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4/entry#A0AAF6Z5A6-1", "sequence": { "sequence": "MDPGAGAFSEEQFREACAELQRPALSGAAWELLVETQGISVYRLLDQTGLYAYKVFGVLEDCLPDLLADVYMDLAYRKQWDQYVKELYEKECSGETVVYWQVKYPFPMSNRDYVYVRQRQELDFEGQKVHVILAQSTSEPQFPEKSGVIRVKHYKQRLAIQSDGKRGSKVFMYYFDNPGGQIPSWVINWAAKNGVPNFLKDMVKACQNYKKT", "length": 212, "header": "tr|A0AAF6Z5A6-1|A0ABI0NTH4_BOVIN Computationally mapped isoform of Phosphatidylcholine transfer protein OS=Bos taurus OX=9913 GN=PCTP PE=4 SV=1 CANONICAL=A0ABI0NTH4-1" }, "locus": { "chromosome": "19", "start_pos": 6255886, "end_pos": 6232335, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024898.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024898.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024898.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024898.6" } ] } }, { "isoform_ac": "A0ABI0NTH4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4/entry#A0ABI0NTH4-1", "sequence": { "sequence": "MDPGAGAFSEEQFREACAELQRPALSGAAWELLVETQGISVYRLLDQQTGLYAYKVFGVLEDCLPDLLADVYMDLAYRKQWDQYVKELYEKECSGETVVYWQVKYPFPMSNRDYVYVRQRQELDFEGQKVHVILAQSTSEPQFPEKSGVIRVKHYKQRLAIQSDGKRGSKVFMYYFDNPGGQIPSWVINWAAKVRPQEARWVVCLTAVYLACGAVSLKRCAISGLMMLFYETAWLMDYVRSVVANTQDRGWDKRQTLEGMPAPPALHQDPSRITFQNLPNSSLFLVGTRVPGTLYLLMEELV", "length": 302, "header": "tr|A0ABI0NTH4-1|A0ABI0NTH4_BOVIN Isoform 1 of Phosphatidylcholine transfer protein OS=Bos taurus OX=9913 GN=PCTP PE=4 SV=1 CANONICAL=A0ABI0NTH4-1" }, "locus": { "chromosome": "19", "start_pos": 6255049, "end_pos": 6232335, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137804.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137804.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104053.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104053.1" } ] } }, { "isoform_ac": "A0ABI0P6P0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4/entry#A0ABI0P6P0-1", "sequence": { "sequence": "MEKTLMLGKNEGGRRKGQQRMRWLDGITDSMHQTGLYAYKVFGVLEDCLPDLLADVYMDLAYRKQWDQYVKELYEKECSGETVVYWQVKYPFPMSNRDYVYVRQRQELDFEGQKVHVILAQSTSEPQFPEKSGVIRVKHYKQRLAIQSDGKRGSKVFMYYFDNPGGQIPSWVINWAAKNGVPNFLKDMVKACQNYKKT", "length": 198, "header": "tr|A0ABI0P6P0-1|A0ABI0P6P0_BOVIN Computationally mapped isoform of Phosphatidylcholine transfer protein OS=Bos taurus OX=9913 GN=PCTP PE=4 SV=1 CANONICAL=A0ABI0NTH4-1" }, "locus": { "chromosome": "19", "start_pos": 6255886, "end_pos": 6236115, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154403.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154403.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107500.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107500.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NTH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTH4" }, { "id": "PS50848", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50848" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "START", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 189, "start_aa": "Trp", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 280, "end_pos": 282 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NR98-1", "uniprot_ac": "A0ABI0NR98", "uniprot_id": "A0ABI0NR98_BOVIN", "mass": { "chemical_mass": 21797.0, "monoisotopic_mass": 21797.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "BolA-like protein 3", "type": "recommended", "evidence": [ { "id": "A0ABI0NR98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR98/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins. Probably acts together with NFU1.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NR98", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR98#function" }, { "database": "UniProtKB", "id": "ARBA00058025", "url": "https://www.uniprot.org/uniprotkb/ARBA00058025#function" }, { "database": "UniProtKB", "id": "A0ABI0P6N3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6N3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NR98", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR98" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR98", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000050675", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000050675", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036065", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036065", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LLF3", "url": "https://www.orthodb.org/?gene=A0A3Q1LLF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46188:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46188:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01722", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01722", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LLF3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NR98", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NR98-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6N3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6N3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6N3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPGSLWRGRVRAPASRPRRKDPLEARAGRQRKPGERADGGALGVLGVRGGSRPPDSRGRPRPWRRRLWSRTPRLSGDAATSDGGPRRPGMAAWSPAAAVPLLRGTRRLPLLHWAQRMFASQTEAELKVTQILKEKFPRATAIKVTDISGGCGAMYEIKIESEEFKEKRTVQQHQMVNQALKEEIKALLWGKAAAVL", "length": 197, "header": "tr|A0ABI0NR98-1|A0ABI0NR98_BOVIN Isoform 1 of BolA-like protein 3 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NR98-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLF3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR98/entry#A0A3Q1LLF3-1", "sequence": { "sequence": "EGRRRGPGRPGRAWRLAASGQQGAASPVAAAALVPDSASFGRRGNLGRRAASAGHGGVEPGRGSASASGNPPGGCGAMYEIKIESEEFKEKRTVQQHQMVNQALKEEIKGMHGLRIFTSVPKH", "length": 123, "header": "tr|A0A3Q1LLF3-1|A0ABI0NR98_BOVIN Computationally mapped isoform of BolA-like protein 3 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=A0ABI0NR98-1" }, "locus": { "chromosome": "11", "start_pos": 10512790, "end_pos": 10505040, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075270.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075270.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060589.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060589.2" } ] } }, { "isoform_ac": "A0ABI0NR98-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR98/entry#A0ABI0NR98-1", "sequence": { "sequence": "MAPGSLWRGRVRAPASRPRRKDPLEARAGRQRKPGERADGGALGVLGVRGGSRPPDSRGRPRPWRRRLWSRTPRLSGDAATSDGGPRRPGMAAWSPAAAVPLLRGTRRLPLLHWAQRMFASQTEAELKVTQILKEKFPRATAIKVTDISGGCGAMYEIKIESEEFKEKRTVQQHQMVNQALKEEIKALLWGKAAAVL", "length": 197, "header": "tr|A0ABI0NR98-1|A0ABI0NR98_BOVIN Isoform 1 of BolA-like protein 3 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NR98-1" }, "locus": { "chromosome": "11", "start_pos": 10514611, "end_pos": 10504933, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147932.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147932.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106153.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106153.1" } ] } }, { "isoform_ac": "A0ABI0P6N3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR98/entry#A0ABI0P6N3-1", "sequence": { "sequence": "MAPGSLWRGRVRAPASRPRRKDPLEARAGRQRKPGERADGGALGVLGVRGGSRPPDSRGRPRPWRRRLWSRTPRLSGDAATSDGGPRRPGMAAWSPAAAVPLLRGTRRLPLLHWAQRMFASQTEAELKVTQILKEKFPRATAIKVTDISGGCGAMYEIKIESEEFKEKRTVQQHQMVNQALKEEIKVLS", "length": 189, "header": "tr|A0ABI0P6N3-1|A0ABI0P6N3_BOVIN Computationally mapped isoform of BolA-like protein 3 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NR98-1" }, "locus": { "chromosome": "11", "start_pos": 10513175, "end_pos": 10504933, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150718.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150718.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106904.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106904.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NTD7-1", "uniprot_ac": "A0ABI0NTD7", "uniprot_id": "A0ABI0NTD7_BOVIN", "mass": { "chemical_mass": 295313.0, "monoisotopic_mass": 295313.0 }, "refseq": { "ac": "XP_024837285", "name": "PDZ domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837285" }, "gene_names": [ { "name": "PDZD2", "type": "recommended", "evidence": [ { "id": "A0ABI0NTD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD7" } ] }, { "name": "PDZD2", "type": "synonym", "evidence": [ { "id": "XP_024837285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837285" } ] } ], "protein_names": [ { "name": "PDZ domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0ABI0NTD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD7/entry#names_and_taxonomy" } ] }, { "name": "PDZ domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024837285", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837285" } ] }, { "name": "PDZ domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "A0ABI0NTD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTD7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PDZD2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD7", "locus": { "chromosome": "20", "start_pos": 41504677, "end_pos": 41605101, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014455", "url": "https://www.ensembl.org/id/ENSBTAG00000014455" } ] } } ], "crossref": [ { "id": "ENSBTAG00000014455", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014455", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06758", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06758", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06759", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06759", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06760", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06760", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06762", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06762", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06763", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06763", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23061", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23061", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "516852", "url": "https://www.ncbi.nlm.nih.gov/gene/516852", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LLW6", "url": "https://www.orthodb.org/?gene=A0A3Q1LLW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11324", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11324", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11324:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11324:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024837285", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837285", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLW6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NL74", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NL74-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTD7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTD7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPITQDNAGLHLPLLYQWLQNSLREGGDGPEQRLCQAAIQKLQEYIRLNFAVDESSIQPDRSPPGMEICTVYLTKELGDAETVGLSFGNIPVFGDYGEKRRGGKKRKTHQGPVLDVGCIWVTELRKNSPAGKSGKVRLRDEILSLNGQLMVGVDVSGASYLAEQCWNGGFIYLIMLRRFKHQVHSPYNGNSSNSSEPGETPTLELGDQTVKKGKRARKFGVIARPSTHKATEESKSSTGCELDHDPVSELDNGLDPELGNGHAFELENGPDLLKEVAGSHLDRSELDRGTEPRIPKTDAPLPTSNDKRRFSKSGKTDFQSSDCLAREEVGRIWKMELLKESDGLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVAILRSATGVVQLVVASKENSAEDLLRLTSKSLPDLTSSTEDVSSWTDNEDQEPDEDEGTGSSSIQSAMPGTEEPHDACGPEESKGNLESPKQGSSKMKLKSRLSGGVHRLESVEEYNELMVRHGDPRARMLEVSRDGRKHSLPQLLDSTGTSQEYHIVKKSTRSLSTTQVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQIRSGLFVLTVRTKLLSPSLTPCSTPTHMSRSSSPNFNASGGTSAGGSDEGSSSLGRKAPGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQILEVNSVNVRHAALSKVHSILSKCPPGPVRLVIGRHPNPKVSEQEMDEVIARSTYQESKEASSSPGLGTPLKSPSFAKKDSLISESELSQYFAHDAPGPLSDFMVAGSEDEDPPGSGGSSSSVEPPSTSPAHKEPGKARANSLVSLGSQRASGLFHKQVTIARQASLPGSPEVLRNPLLRQRRVGCSDDDASDEEEFDGEGDCISLPGTLSGPSRPLTEDNSTHVSTASSKVTGINREEHPKKTLVSKASSVPLLGSSLDFQESLPGGVRDPLSHAASLLVPSEAPKGSPGCSGRKELSGSRSSPKLECRAGTGTQGPASTDSPSSLQQNDSLGSRHKPVARVSPHRKRPEAEARPSSAESAQLTDGASDPRGADLKVQDSSIQVTVTGYRPGGTVEKESLDKPSVGDGRVPTEWGPGGALPHPDASHPTENPPAATSKQPGTGPDGSPDPLPSPGQKEAAHPDPSQTSVDTEPARRPEDPGGPESPRIPKSEDSTSPGTMAMARPDLREMRAAPNASSPCAARKAATPRGAGPMAEGAPSTGAGLPQDLMSGEKSQERVLGHHAKAPQTSAVLAPENCQGSALPQGTDSGSTSAPQAGLALPSLSDKAQEACGGASGPGCPGGNGRCPVTDIDRLLVEPDVSGARLPSPGKGDWLSREQAAQGPQLASGSPTPAPRRPGAAGPAPPPQWAGQPSVLDSINPDRHFTVNKSFLSNYSRNLSSLHEDSTSLSGLGDSTEPSVSLSSMYGDVEDSSSDPESFTDAPRAPPRDSWSPPHPRPPEPSHKGDATESEEEQVEICSTDGSPDRPSATALAPARVAACPALATALPPKDGALSQVGAEAGHTARFVPGTSTPPQPPPPLSDVSSQEAEPPEDARVSQDHRSPSEEDSGEATQPPPGTRPIPSSLGTLGSPNVVNGLEYDHLDDKAPPEKQEIDVHTAENQASFRACVPKNGDSALGNLHISGGQGPEDLLPKPKAISRRPLMAWFREINKNNHGTHPQSKTEMEQSTLLARSPDPKAQVLSSSHKKGVPVPDSPPPRLNLENKDLPRKSSVETLLSNCQKPKAGPKLKRLSIKSKSKVSSEVPAAHTGKTGSTEHRKALVSPQASHKMLSKVASHRFHTADHEELDKTAAAAPQSPQCVEGKLPPGTPGSLKPSASDSSIRMFVSPVTTPKTLPEQGGCGRLHPAVHAEPDRGFPAAPSPPKCGPESRAPLASPGPASPAALRSGTSTVAGKLEVPTPGQGEWSLSSQTDSAAEAALPGVTGDKRSKIIASEPLERTKQLKIIEIPKSTCGDILAERDRQGGLLSQSSHQEESEAGLCHQPGESSPNHPSFLPTRVSQVELEAQQRSVSLARLSSSSSPQLLARKADPGQMGNPLGVPRNGPPVGPVLDDHPYFTPRPATRTYSMPAQFSSHFGREGHTPQSPGRTPRDGQIPGTSGGLLEAKASRGAVLSLANGQGVYSVKPLLETSGNLPTTDEADVLSAQETSCQLTDRVTVTRRHHYSPQNWPHEATSFFSVKQRIKSFENLAHSDRPAAKAGASSFLSVSSKPPIGRRSSGSVVSGPLSHSSDPTARLLRRSLSSCSESQGEATTVVPPMTKSPSSMTLTVSRQTPADARNKGADSDPKRPPGPSGIPAPTATPASPAKRNKSSVRHTQASPLSRSKLQELRALSMPDLDKLCSEDFSAGPSAVLFKTELEIVPRRSRGSPAGGLAGSTALSCPKDGAERACPKATDPRAPSSAHDVGETAQDLPSGRSWSVNLQQLLVSAGDQQRLQSILSSVGSRSTVLTLIQEAKAQSENKEDICFIVLNKKEGSGLGFSVAGGTDVQPKSIVVHRVFSQGAASQEGTVSRGDFLLSLNGASLAGLAHGDVLKALHQAQLHKDVLMVIKKGSDQPRPSSRQEPPTANGKGLVSRKTSPLEPGTAGRSTAAHEALCVEVLKTSAGLGLSLDGGKSSMSGDGPLLVKRVYKGGAAEQAGTIEAGDEILAINGKSLVGLMHFDAWNIMKAVPEGPVQLVIRKHRNSSCSKHW", "length": 2805, "header": "tr|A0ABI0NTD7-1|A0ABI0NTD7_BOVIN Isoform 1 of PDZ domain-containing protein 2 OS=Bos taurus OX=9913 GN=PDZD2 PE=4 SV=1 CANONICAL=A0ABI0NTD7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLW6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD7/entry#A0A3Q1LLW6-1", "sequence": { "sequence": "MLRRFKHQVHSPYNGNSSNSSEPGETPTLELGDQTVKKGKRARKFGVIARPSTHKATEESKSSTGCELDHDPVSELDNGLDPELGNGHAFELENGPDLLKEVAGSHLDRSELDRGTEPRIPKTDAPLPTSNDKRRFSKSGKTDFQSSDCLAREEVGRIWKMELLKESDGLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVAILRSATGVVQLVVASKENSAEDLLRLTSKSLPDLTSSTEDVSSWTDNEDQEPDEDEGTGSSSIQSAMPGTEEPHDACGPEESKGNLESPKQGSSKMKLKSRLSGGVHRLESVEEYNELMVRHGDPRARMLEVSRDGRKHSLPQLLDSTGTSQEYHIVKKSTRSLSTTQVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQIRSGLFVLTVRTKLLSPSLTPCSTPTHMSRSSSPNFNASGGTSAGGSDEGSSSLGRKAPGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQILEVNSVNVRHAALSKVHSILSKCPPGPVRLVIGRHPNPKVSEQEMDEVIARSTYQESKEASSSPGLGTPLKSPSFAKKDSLISESELSQYFAHDAPGPLSDFMVAGSEDEDPPGSGGSSSSVEPPSTSPHKEPGKARANSLVSLGSQRASGLFHKQVTIARQASLPGSPEVLRNPLLRQRRVGCSDDDASDEEEFDGEGDCISLPGTLSGPSRPLTEDNSTHVSTASSKVTGINREEHPKKTLVSKASSVPLLGSSLDFQESLPGGVRDPLSHAASLLVPSEAPKGSPGCSGRKELSGSRSSPKLECRAGTGTQGPASTDSPSSLQQNDSLGSRHKPVARVSPHRKRPEAEARPSSAESAQLTDGASDPRGADLKVQDSSIQVTVTGYRPGGTVEKESLDKPSVGDGRVPTEWGPGGALPHPDASHPTENPPAATSKQPGTGPDGSPDPLPSPGQKEAAHPDPSQTSVDTEPARRPEDPGGPESPRIPKSEDSTSPGTMAMARPDLREMRAAPNASSPCAARKAATPRGAGPMAEGAPSTGAGLPQDLMSGEKSQERVLGHHAKAPQTSAVLAPENCQGSALPQGTDSGSTSAPQAGLALPSLSDKAQEACGGASGPGCPGGNGRCPVTDIDRLLVEPDVSGARLPSPGKGDWLSREQAAQGPQLASGSPTPAPRRPGAAGPAPPPQWAGQPSVLDSINPDRHFTVNKSFLSNYSRNLSSLHEDSTSLSGLGDSTEPSVSLSSMYGDVEDSSSDPESFTDAPRAPPRDSWSPPHPRPPEPSHKGDATESEEEQVEICSTDGSPDRPSATALAPARVAACPALATALPPKDGALSQVGAEAGHTARFVPGTSTPPQPPPPLSDVSSQEAEPPEDARVSQDHRSPSEEDSGEATQPPPGTRPIPSSLGTLGSPNVVNGLEYDHLDDKAPPEKQEIDVHTAENQASFRACVPKNGDSALGNLHISGGQGPEDLLPKPKAISRRPLMAWFREINKNNHGTHPQSKTEMEQSTLLARSPDPKAQVLSSSHKKGVPVPDSPPPRLNLENKDLPRKSSVETLLSNCQKPKAGPKLKRLSIKSKSKVSSEVPAAHTGKTGSTEHRKALVSPQASHKMLSKVASHRFHTADHEELDKTAAAAPQSPQCVEGKLPPGTPGSLKPSASDSSIRMFVSPVTTPKTLPEQGGCGRLHPAVHAEPDRGFPAAPSPPKCGPESRAPLASPGPASPAALRSGTSTVAGKLEVPTPGQGEWSLSSQTDSAAEAALPGVTGDKRSKIIASEPLERTKQLKIIEIPKSTCGDILAERDRQGGLLSQSSHQEESEAGLCHQPGESSPNHPSFLPTRVSQVELEAQQRSVSLARLSSSSSPQLLARKADPGQMGNPLGVPRNGPPVGPVLDDHPYFTPRPATRTYSMPAQFSSHFGREGHTPQSPGRTPRDGQIPGTSGGLLEAKASRGAVLSLANGQGVYSVKPLLETSGNLPTTDEADVLSAQETSCQLTDRVTVTRRHHYSPQNWPHEATSFFSVKQRIKSFENLAHSDRPAAKAGASSFLSVSSKPPIGRRSSGSVVSGPLSHSSDPTARLLRRSLSSCSESQGEATTVVPPMTKSPSSMTLTVSRQTPADARNKGADSDPKRPPGPSGIPAPTATPASPAKRNKSSVRHTQASPLSRSKLQELRALSMPDLDKLCSEDFSAGPSAVLFKTELEIVPRRSRGSPAGGLAGSTALSCPKDGAERACPKATDPRAPSSAHDVGETAQDLPSGRSWSVNLQQLLVSAGDQQRLQSILSSVGSRSTVLTLIQEAKAQSENKEDICFIVLNKKEGSGLGFSVAGGTDVQPKSIVVHRVFSQGAASQEGTVSRGDFLLSLNGASLAGLAHGDVLKALHQAQLHKDVLMVIKKGSDQPRPSSRQEPPTANGKGLVSRKTSPLEPGTAGRSTAAHEALCVEVLKTSAGLGLSLDGGKSSMSGDGPLLVKRVYKGGAAEQAGTIEAGDEILAINGKSLVGLMHFDAWNIMKAVPEGPVQLVIRKHRNSSCSKHW", "length": 2630, "header": "tr|A0A3Q1LLW6-1|A0ABI0NTD7_BOVIN Computationally mapped isoform of PDZ domain-containing protein 2 OS=Bos taurus OX=9913 GN=PDZD2 PE=4 SV=2 CANONICAL=A0ABI0NTD7-1" }, "locus": { "chromosome": "20", "start_pos": 41605055, "end_pos": 41505681, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082467.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082467.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057790.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057790.2" } ] } }, { "isoform_ac": "A0ABI0NL74-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD7/entry#A0ABI0NL74-1", "sequence": { "sequence": "MPITQDNAGLHLPLLYQWLQNSLREGGDGPEQRLCQAAIQKLQEYIRLNFAVDESSIQPDRSPPGMEICTVYLTKELGDAETVGLSFGNIPVFGDYGEKRRGGKKRKTHQGPVLDVGCIWVTELRKNSPAGKSGKVRLRDEILSLNGQLMVGVDVSGASYLAEQCWNGGFIYLIMLRRFKHQVHSPYNGNSSNSSEPGETPTLELGDQTVKKGKRARKFGVIARPSTHKATEESKSSTGCELDHDPVSELDNGLDPELGNGHAFELENGPDLLKEVAGSHLDRSELDRGTEPRIPKTDAPLPTSNDKRRFSKSGKTDFQSSDCLARENSAEDLLRLTSKSLPDLTSSTEDVSSWTDNEDQEPDEDEGTGSSSIQSAMPGTEEPHDACGPEESKGNLESPKQGSSKMKLKSRLSGGVHRLESVEEYNELMVRHGDPRARMLEVSRDGRKHSLPQLLDSTGTSQEYHIVKKSTRSLSTTQVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQIRSGLFVLTVRTKLLSPSLTPCSTPTHMSRSSSPNFNASGGTSAGGSDEGSSSLGRKAPGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQILEVNSVNVRHAALSKVHSILSKCPPGPVRLVIGRHPNPKVSEQEMDEVIARSTYQESKEASSSPGLGTPLKSPSFAKKDSLISESELSQYFAHDAPGPLSDFMVAGSEDEDPPGSGGSSSSVEPPSTSPAHKEPGKARANSLVSLGSQRASGLFHKQVTIARQASLPGSPEVLRNPLLRQRRVGCSDDDASDEEEFDGEGDCISLPGTLSGPSRPLTEDNSTHVSTASSKVTGINREEHPKKTLVSKASSVPLLGSSLDFQESLPGGVRDPLSHAASLLVPSEAPKGSPGCSGRKELSGSRSSPKLECRAGTGTQGPASTDSPSSLQQNDSLGSRHKPVARVSPHRKRPEAEARPSSAESAQLTDGASDPRGADLKVQDSSIQVTVTGYRPGGTVEKESLDKPSVGDGRVPTEWGPGGALPHPDASHPTENPPAATSKQPGTGPDGSPDPLPSPGQKEAAHPDPSQTSVDTEPARRPEDPGGPESPRIPKSEDSTSPGTMAMARPDLREMRAAPNASSPCAARKAATPRGAGPMAEGAPSTGAGLPQDLMSGEKSQERVLGHHAKAPQTSAVLAPENCQGSALPQGTDSGSTSAPQAGLALPSLSDKAQEACGGASGPGCPGGNGRCPVTDIDRLLVEPDVSGARLPSPGKGDWLSREQAAQGPQLASGSPTPAPRRPGAAGPAPPPQWAGQPSVLDSINPDRHFTVNKSFLSNYSRNLSSLHEDSTSLSGLGDSTEPSVSLSSMYGDVEDSSSDPESFTDAPRAPPRDSWSPPHPRPPEPSHKGDATESEEEQVEICSTDGSPDRPSATALAPARVAACPALATALPPKDGALSQVGAEAGHTARFVPGTSTPPQPPPPLSDVSSQEAEPPEDARVSQDHRSPSEEDSGEATQPPPGTRPIPSSLGTLGSPNVVNGLEYDHLDDKAPPEKQEIDVHTAENQASFRACVPKNGDSALGNLHISGGQGPEDLLPKPKAISRRPLMAWFREINKNNHGTHPQSKTEMEQSTLLARSPDPKAQVLSSSHKKGVPVPDSPPPRLNLENKDLPRKSSVETLLSNCQKPKAGPKLKRLSIKSKSKVSSEVPAAHTGKTGSTEHRKALVSPQASHKMLSKVASHRFHTADHEELDKTAAAAPQSPQCVEGKLPPGTPGSLKPSASDSSIRMFVSPVTTPKTLPEQGGCGRLHPAVHAEPDRGFPAAPSPPKCGPESRAPLASPGPASPAALRSGTSTVAGKLEVPTPGQGEWSLSSQTDSAAEAALPGVTGDKRSKIIASEPLERTKQLKIIEIPKSTCGDILAERDRQGGLLSQSSHQEESEAGLCHQPGESSPNHPSFLPTRVSQVELEAQQRSVSLARLSSSSSPQLLARKADPGQMGNPLGVPRNGPPVGPVLDDHPYFTPRPATRTYSMPAQFSSHFGREGHTPQSPGRTPRDGQIPGTSGGLLEAKASRGAVLSLANGQGVYSVKPLLETSGNLPTTDEADVLSAQETSCQLTDRVTVTRRHHYSPQNWPHEATSFFSVKQRIKSFENLAHSDRPAAKAGASSFLSVSSKPPIGRRSSGSVVSGPLSHSSDPTARLLRRSLSSCSESQGEATTVVPPMTKSPSSMTLTVSRQTPADARNKGADSDPKRPPGPSGIPAPTATPASPAKRNKSSVRHTQASPLSRSKLQELRALSMPDLDKLCSEDFSAGPSAVLFKTELEIVPRRSRGSPAGGLAGSTALSCPKDGAERACPKATDPRAPSSAHDVGETAQDLPSGRSWSVNLQQLLVSAGDQQRLQSILSSVGSRSTVLTLIQEAKAQSENKEDICFIVLNKKEGSGLGFSVAGGTDVQPKSIVVHRVFSQGAASQEGTVSRGDFLLSLNGASLAGLAHGDVLKALHQAQLHKDVLMVIKKGSDQPRPSSRQEPPTANGKGLVSRKTSPLEPGTAGRSTAAHEALCVEVLKTSAGLGLSLDGGKSSMSGDGPLLVKRVYKGGAAEQAGTIEAGDEILAINGKSLVGLMHFDAWNIMKAVPEGPVQLVIRKHRNSSCSKHW", "length": 2713, "header": "tr|A0ABI0NL74-1|A0ABI0NTD7_BOVIN Computationally mapped isoform of PDZ domain-containing protein 2 OS=Bos taurus OX=9913 GN=PDZD2 PE=4 SV=1 CANONICAL=A0ABI0NTD7-1" }, "locus": { "chromosome": "20", "start_pos": 41757846, "end_pos": 41505681, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140506.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140506.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105761.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105761.1" } ] } }, { "isoform_ac": "A0ABI0NTD7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD7/entry#A0ABI0NTD7-1", "sequence": { "sequence": "MPITQDNAGLHLPLLYQWLQNSLREGGDGPEQRLCQAAIQKLQEYIRLNFAVDESSIQPDRSPPGMEICTVYLTKELGDAETVGLSFGNIPVFGDYGEKRRGGKKRKTHQGPVLDVGCIWVTELRKNSPAGKSGKVRLRDEILSLNGQLMVGVDVSGASYLAEQCWNGGFIYLIMLRRFKHQVHSPYNGNSSNSSEPGETPTLELGDQTVKKGKRARKFGVIARPSTHKATEESKSSTGCELDHDPVSELDNGLDPELGNGHAFELENGPDLLKEVAGSHLDRSELDRGTEPRIPKTDAPLPTSNDKRRFSKSGKTDFQSSDCLAREEVGRIWKMELLKESDGLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVAILRSATGVVQLVVASKENSAEDLLRLTSKSLPDLTSSTEDVSSWTDNEDQEPDEDEGTGSSSIQSAMPGTEEPHDACGPEESKGNLESPKQGSSKMKLKSRLSGGVHRLESVEEYNELMVRHGDPRARMLEVSRDGRKHSLPQLLDSTGTSQEYHIVKKSTRSLSTTQVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQIRSGLFVLTVRTKLLSPSLTPCSTPTHMSRSSSPNFNASGGTSAGGSDEGSSSLGRKAPGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQILEVNSVNVRHAALSKVHSILSKCPPGPVRLVIGRHPNPKVSEQEMDEVIARSTYQESKEASSSPGLGTPLKSPSFAKKDSLISESELSQYFAHDAPGPLSDFMVAGSEDEDPPGSGGSSSSVEPPSTSPAHKEPGKARANSLVSLGSQRASGLFHKQVTIARQASLPGSPEVLRNPLLRQRRVGCSDDDASDEEEFDGEGDCISLPGTLSGPSRPLTEDNSTHVSTASSKVTGINREEHPKKTLVSKASSVPLLGSSLDFQESLPGGVRDPLSHAASLLVPSEAPKGSPGCSGRKELSGSRSSPKLECRAGTGTQGPASTDSPSSLQQNDSLGSRHKPVARVSPHRKRPEAEARPSSAESAQLTDGASDPRGADLKVQDSSIQVTVTGYRPGGTVEKESLDKPSVGDGRVPTEWGPGGALPHPDASHPTENPPAATSKQPGTGPDGSPDPLPSPGQKEAAHPDPSQTSVDTEPARRPEDPGGPESPRIPKSEDSTSPGTMAMARPDLREMRAAPNASSPCAARKAATPRGAGPMAEGAPSTGAGLPQDLMSGEKSQERVLGHHAKAPQTSAVLAPENCQGSALPQGTDSGSTSAPQAGLALPSLSDKAQEACGGASGPGCPGGNGRCPVTDIDRLLVEPDVSGARLPSPGKGDWLSREQAAQGPQLASGSPTPAPRRPGAAGPAPPPQWAGQPSVLDSINPDRHFTVNKSFLSNYSRNLSSLHEDSTSLSGLGDSTEPSVSLSSMYGDVEDSSSDPESFTDAPRAPPRDSWSPPHPRPPEPSHKGDATESEEEQVEICSTDGSPDRPSATALAPARVAACPALATALPPKDGALSQVGAEAGHTARFVPGTSTPPQPPPPLSDVSSQEAEPPEDARVSQDHRSPSEEDSGEATQPPPGTRPIPSSLGTLGSPNVVNGLEYDHLDDKAPPEKQEIDVHTAENQASFRACVPKNGDSALGNLHISGGQGPEDLLPKPKAISRRPLMAWFREINKNNHGTHPQSKTEMEQSTLLARSPDPKAQVLSSSHKKGVPVPDSPPPRLNLENKDLPRKSSVETLLSNCQKPKAGPKLKRLSIKSKSKVSSEVPAAHTGKTGSTEHRKALVSPQASHKMLSKVASHRFHTADHEELDKTAAAAPQSPQCVEGKLPPGTPGSLKPSASDSSIRMFVSPVTTPKTLPEQGGCGRLHPAVHAEPDRGFPAAPSPPKCGPESRAPLASPGPASPAALRSGTSTVAGKLEVPTPGQGEWSLSSQTDSAAEAALPGVTGDKRSKIIASEPLERTKQLKIIEIPKSTCGDILAERDRQGGLLSQSSHQEESEAGLCHQPGESSPNHPSFLPTRVSQVELEAQQRSVSLARLSSSSSPQLLARKADPGQMGNPLGVPRNGPPVGPVLDDHPYFTPRPATRTYSMPAQFSSHFGREGHTPQSPGRTPRDGQIPGTSGGLLEAKASRGAVLSLANGQGVYSVKPLLETSGNLPTTDEADVLSAQETSCQLTDRVTVTRRHHYSPQNWPHEATSFFSVKQRIKSFENLAHSDRPAAKAGASSFLSVSSKPPIGRRSSGSVVSGPLSHSSDPTARLLRRSLSSCSESQGEATTVVPPMTKSPSSMTLTVSRQTPADARNKGADSDPKRPPGPSGIPAPTATPASPAKRNKSSVRHTQASPLSRSKLQELRALSMPDLDKLCSEDFSAGPSAVLFKTELEIVPRRSRGSPAGGLAGSTALSCPKDGAERACPKATDPRAPSSAHDVGETAQDLPSGRSWSVNLQQLLVSAGDQQRLQSILSSVGSRSTVLTLIQEAKAQSENKEDICFIVLNKKEGSGLGFSVAGGTDVQPKSIVVHRVFSQGAASQEGTVSRGDFLLSLNGASLAGLAHGDVLKALHQAQLHKDVLMVIKKGSDQPRPSSRQEPPTANGKGLVSRKTSPLEPGTAGRSTAAHEALCVEVLKTSAGLGLSLDGGKSSMSGDGPLLVKRVYKGGAAEQAGTIEAGDEILAINGKSLVGLMHFDAWNIMKAVPEGPVQLVIRKHRNSSCSKHW", "length": 2805, "header": "tr|A0ABI0NTD7-1|A0ABI0NTD7_BOVIN Isoform 1 of PDZ domain-containing protein 2 OS=Bos taurus OX=9913 GN=PDZD2 PE=4 SV=1 CANONICAL=A0ABI0NTD7-1" }, "locus": { "chromosome": "20", "start_pos": 41757846, "end_pos": 41505681, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147417.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147417.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106679.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106679.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1448, "start_aa": "Thr", "end_pos": 1448, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1448", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1925, "start_aa": "Thr", "end_pos": 1925, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1925", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2015, "start_aa": "Thr", "end_pos": 2015, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2015", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2416, "start_aa": "Thr", "end_pos": 2416, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2416", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTD7", "url": 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72327199, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011292", "url": "https://www.ensembl.org/id/ENSBTAG00000011292" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011292", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011292", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18308", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18308", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18309", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18309", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18505", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18505", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18506", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18506", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BLW3", "url": "https://www.orthodb.org/?gene=E1BLW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46376:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46376:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NT07", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT07-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P168", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P168", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P168-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P168-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3Y2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLW3", "url": "https://www.uniprot.org/uniprotkb/E1BLW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLW3-1", "url": "https://www.uniprot.org/uniprotkb/E1BLW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPGGSGGPIGAGALAGGARSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPAAVCRDRMFVFSGQSGAKITNNLFQFEFKDQTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEVIQPSSDSEVGGAEMPERASASEEVPAPGSEERAGCKKSRDVFGLDFGSTTSRQPSLPASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWESRQFCDVEFVLGEKEERVQGHVAIVTARSRWLRRKIAQARVRPRKLEEEAAPAPREGPAAAAGAARPALLRVAIREAEARPFEVLMQFLYTDKIQYPRKGHVEDVLLIMDVYKLALGFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLGQLKEHCLNFVVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRAPSDQPVDIGTSLIQDMKAYLEGAGAEFCDITLLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAFESMLRYIYYGEVNMPPEDSLYLFSAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQILEAADKTQALDMKRHCLHIIVHQFTKVSKLPTLRSLSQQLLLDIIDSLASHISDKQCAELGADI", "length": 839, "header": "tr|A0ABI0NT07-1|A0ABI0NT07_BOVIN Isoform 1 of Leucine-zipper-like transcriptional regulator 1 OS=Bos taurus OX=9913 GN=LZTR1 PE=3 SV=1 CANONICAL=A0ABI0NT07-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NT07-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT07/entry#A0ABI0NT07-1", "sequence": { "sequence": "MAGPGGSGGPIGAGALAGGARSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPAAVCRDRMFVFSGQSGAKITNNLFQFEFKDQTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEVIQPSSDSEVGGAEMPERASASEEVPAPGSEERAGCKKSRDVFGLDFGSTTSRQPSLPASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWESRQFCDVEFVLGEKEERVQGHVAIVTARSRWLRRKIAQARVRPRKLEEEAAPAPREGPAAAAGAARPALLRVAIREAEARPFEVLMQFLYTDKIQYPRKGHVEDVLLIMDVYKLALGFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLGQLKEHCLNFVVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRAPSDQPVDIGTSLIQDMKAYLEGAGAEFCDITLLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAFESMLRYIYYGEVNMPPEDSLYLFSAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQILEAADKTQALDMKRHCLHIIVHQFTKVSKLPTLRSLSQQLLLDIIDSLASHISDKQCAELGADI", "length": 839, "header": "tr|A0ABI0NT07-1|A0ABI0NT07_BOVIN Isoform 1 of Leucine-zipper-like transcriptional regulator 1 OS=Bos taurus OX=9913 GN=LZTR1 PE=3 SV=1 CANONICAL=A0ABI0NT07-1" }, "locus": { "chromosome": "17", "start_pos": 72338980, "end_pos": 72327212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147314.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147314.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106416.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106416.1" } ] } }, { "isoform_ac": "A0ABI0P168-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT07/entry#A0ABI0P168-1", "sequence": { "sequence": "MAGPGGSGGPIGAGALAGGARSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPAAVCRDRMFVFSGQSGAKITNNLFQFEFKDQTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEVIQPSSDSEVGGAEMPERASASEEVPAPGSEERAGCKKSRDVFGLDFGSTTSRQPSLPASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWESRQFCDVEFVLGEKEERVQGHVAIVTARSRWLRRKIAQARKLEEEAAPAPREGPAAAAGAARPALLRVAIREAEARPFEVLMQFLYTDKIQYPRKGHVEDVLLIMDVYKLALGFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLGQLKEHCLNFVVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRAPSDQPVDIGTSLIQDMKAYLEGAGAEFCDITLLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAFESMLRYIYYGEVNMPPEDSLHPSLRASGHARQPWTPPARGWAVSQGFLVAPSPLSSLEQSVQLRGVCSQEGWGASRTRGSQPCLLRAGRCRGGRGWVCRCVGDFPWERSLGCSLDPELGPGPPSGSEPRQRAGLPCLDGSPASWWWAGPSCAEAGQPRLRVEGRQARLAGGSLTSPQLPVLGALLLRLLQQPAAGLLQAEPGDERDGAERATGVALALRVRAGAGRAAGAAPQGARCCRSWRRRTRRRPWT", "length": 966, "header": "tr|A0ABI0P168-1|A0ABI0P168_BOVIN Computationally mapped isoform of Leucine zipper like post translational regulator 1 OS=Bos taurus OX=9913 GN=LZTR1 PE=4 SV=1 CANONICAL=A0ABI0NT07-1" }, "locus": { "chromosome": "17", "start_pos": 72338597, "end_pos": 72327212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145433.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145433.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104908.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104908.1" } ] } }, { "isoform_ac": "A0ABI0P3Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT07/entry#A0ABI0P3Y2-1", "sequence": { "sequence": "MAGPGGSGGPIGAGALAGGARSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPAAVCRDRMFVFSGQSGAKITNNLFQFEFKDQTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEVIQPSSDSEVGGAEMPERASASEEVPAPGSEERAGCKKSRDVFGLDFGSTTSRQPSLPASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWESRQFCDVEFVLGEKEERVQGHVAIVTARSRWLRRKIAQARKLEEEAAPAPREGPAAAAGAARPALLRVAIREAEARPFEVLMQFLYTDKIQYPRKGHVEDVLLIMDVYKLALGFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLGQLKEHCLNFVVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRAPSDQPVDIGREPASSEGRGHLGHRVQPRATHAQVRPGLGPDEGWARPSDARCLLLLSPPSREGTLGSRHVSDPGHEGILGGRGRGVLRHHPPAGRAPAASPQGHPGRPLQLLRGHVPVLHARGRPGEHLHWGDGAQQAGLRVHAALHLLWRGQHAARGLPAS", "length": 796, "header": "tr|A0ABI0P3Y2-1|A0ABI0P3Y2_BOVIN Computationally mapped isoform of Leucine zipper like post translational regulator 1 OS=Bos taurus OX=9913 GN=LZTR1 PE=4 SV=1 CANONICAL=A0ABI0NT07-1" }, "locus": { "chromosome": "17", "start_pos": 72337909, "end_pos": 72327212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144131.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144131.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106387.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106387.1" } ] } }, { "isoform_ac": "E1BLW3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT07/entry#E1BLW3-1", "sequence": { "sequence": "MAGPGGSGGPIGAGALAGGARSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPAAVCRDRMFVFSGQSGAKITNNLFQFEFKDQTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEVIQPSSDSEVGGAEMPERASASEEVPAPGSEERAGCKKSRDVFGLDFGSTTSRQPSLPASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWESRQFCDVEFVLGEKEERVQGHVAIVTARSRWLRRKIAQARVRPRKLEEEAAPAPREGPAAAAGAARPALLRVAIREAEARPFEVLMQFLYTDKIQYPRKGHVEDVLLIMDVYKLALGFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLGQLKEHCLNFVVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRAPSDQPVDIGTSLIQDMKAYLEGAGAEFCDITLLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAFESMLRYIYYGEVNMPPEDSLYLFSAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQVSKLPTLRSLSQQLLLDIIDSLASHISDKQCAELGADI", "length": 812, "header": "tr|E1BLW3-1|A0ABI0NT07_BOVIN Computationally mapped isoform of Leucine-zipper-like transcriptional regulator 1 OS=Bos taurus OX=9913 GN=LZTR1 PE=3 SV=4 CANONICAL=A0ABI0NT07-1" }, "locus": { "chromosome": "17", "start_pos": 72338980, "end_pos": 72327212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015001.8", "url": "https://www.ensembl.org/id/ENSBTAT00000015001.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015001.7", "url": "https://www.ensembl.org/id/ENSBTAP00000015001.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of Ras protein signal transduction", "id": "GO:0046580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046580", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT07", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT07" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT07", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT07" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT07", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT07" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT07", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT07" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT07", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT07" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 706, "end_pos": 708, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NT07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT07" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 443, "end_pos": 536, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 706, "end_pos": 708 }, { "start_pos": 766, "end_pos": 768 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NRG9-1", "uniprot_ac": "A0ABI0NRG9", "uniprot_id": "A0ABI0NRG9_BOVIN", "mass": { "chemical_mass": 199596.0, "monoisotopic_mass": 199596.0 }, "refseq": { "ac": "NP_001411718", "name": "BTB/POZ domain-containing protein 8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001411718" }, "gene_names": [ { "name": "BTBD8", "type": "recommended", "evidence": [ { "id": "A0ABI0NRG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG9" } ] }, { "name": "BTBD8", "type": "synonym", "evidence": [ { "id": "NP_001411718", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001411718" } ] } ], "protein_names": [ { "name": "BTB/POZ domain-containing protein 8", "type": "recommended", "evidence": [ { "id": "A0ABI0NRG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG9/entry#names_and_taxonomy" } ] }, { "name": "BTB (POZ) domain containing 8", "type": "synonym", "evidence": [ { "id": "NP_001411718", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001411718" } ] }, { "name": "BTB/POZ domain-containing protein 8", "type": "synonym", "evidence": [ { "id": "NP_001411718", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001411718" } ] } ], "function": [ { "annotation": "Involved in clathrin-mediated endocytosis at the synapse. Plays a role in neuronal development and in synaptic vesicle recycling in mature neurons, a process required for normal synaptic transmission.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRG9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG9#function" }, { "database": "UniProtKB", "id": "ARBA00058836", "url": "https://www.uniprot.org/uniprotkb/ARBA00058836#function" }, { "database": "UniProtKB", "id": "A0ABI0NRJ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRJ4#function" }, { "database": "UniProtKB", "id": "E1BNE4", "url": "https://www.uniprot.org/uniprotkb/E1BNE4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRG9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BTBD8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG9", "locus": { "chromosome": "3", "start_pos": 51222912, "end_pos": 51242518, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006167", "url": "https://www.ensembl.org/id/ENSBTAG00000006167" } ] } } ], "crossref": [ { "id": "ENSBTAG00000006167", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006167", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18285", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18285", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18286", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18286", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18490", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18490", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "520456", "url": "https://www.ncbi.nlm.nih.gov/gene/520456", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22427:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22427:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001411718", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001411718", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NRG9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRG9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRJ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNE4", "url": "https://www.uniprot.org/uniprotkb/E1BNE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNE4-1", "url": "https://www.uniprot.org/uniprotkb/E1BNE4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARCGEDSASPGVPLGSPGVCSKGLQRKGPCERRRLKAMVSEQLSQDLLRLLREEVHTDVTFSIGCTLFKAHKAVLLARVPDFYFHTVGHTDNLKNHEHVTVENFEASEFRTFLQIVYSSNRNIKSYEEEILRKKIVESGVPQKKCDFSVGNCTDHDRRLSVEFLSKRSSDHSLLKHEIPKDINSKEENVISTDIYDLEPASELGEDLLKLYVKHCCPDIDIYVDGKSFKAHRAILSARSSYFAAMLSGCWAESSQECVTLQSISHVEMNVMMHFIYGGTLDFPVKANVGQILNMADMYGLEGLKEVAIYILRRDYCNFFQKPVSRRLASILECLIIAHSVGVESLFADCMKWIVKHFARFWSERSFANVPPEIQKSCFNMLIHSLNDKNAAFLLMESDRLIVSLPRVKWTESALIMASQLQEECIAFIIENFSKIIQSENFALLLQSQAMSSTSDLLDKIFKAVEENITTENSCSLLMALDTLLNSDSTKEMGFTCKIQALRDKLWIFLVQSFYAVRHTESWKLMSTDDQQKIQAAAFDKGDDRRLGKKPIFSSSQQRKQVSDCGAIKNKSAGGSNKKQCLSYLSAHQKMKSDGLGASGHSSSTNRNSINKTLKHDDLKEKDPKPASKSTKELKTVEKNVSGKPKAIIKPKTENSDNAKSTNLSPRQAVERSATAAANEQKNSGNGKGVRNQEEQITGARPKVLTGNLNVQAKAKPLKKVTGKDSPHLRMAGPSSRSTNSSMELLTSTDSLDEPKENGSMKEKLPGHKPSSCDSRGQTVKNSVEGIKTSTVAMKYRPVSKDTNGISNKKSTHEQESNTHNSVLKKITSKGYSDPVPQAILKKRGNGNGCATAPQRTKNATANLAKTQGSQGSPNSVKSSVSSRQSDENVTKLDHSVTTDKQTPKRKIVKQGQTTLPKIGAKKVTMPKNPNQPKRGENLNNKDAKPKTLPEQVILKTLPSSQRPLKSEPSVVQKSVSLDVCDNNNKGSVSEQKPHEPLTNLTAKTSDAEAFQSPCILDSQKTLNNQEKQKLVLECQNISNLDKLIKRELESKQICSVKSETNVSGHKKIDHCTTAKIPCHSDETDNVDPKFYSTTALKSMISNPKENSLNSNPVCDLDSAHVEQLHSELDRKKQVGRKDTNQKLSIKCVKDVLPWVPEKTNGTLNSGQDDRKSKIHVEEQTVPSQLSDDSAMNEDNHATVESHISSKCFLEQISGKNSKDTETTETSESHETPEAPFMSHWNLSTNVLHQRESPESDSGSVTTSSDDIKPRSEDYDAGGSQDDDGSNDRGVSKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQGSSDLFQVNSTSDDEIPRKRPEIWSRSTIVHPREKENIPRGSVQFVQEVDQVSSSADETEDERSEAENVAENFSTSNPALQQFQGIINLAFEDATENESHEFRVTKSFKRSVLLSVDECEEIGSDEGEVHALFQPSVDSLSPSDVFDGISHEHHGRTCYSRYSHGSEGGVLECRQKKSNTIYKNKSFPLGLSSVDSSRKDKQSASATEKKGTTDVLSKGGIQLPPGDKVCSGSNVDNDFETHSKFSDSDIKSQERPCHLELRQRESNSDIPKNSFTKSLDSCRSQVLPQEGQVKESHSTATEKANIALSAGDIDGCDTVAQIYMYDHRPSKTLSPIYEMDVTEAFEQKMESETQGTDMDFEDEQHFAKQDWTLLKQLLSEQDSNLNITNSVPEDLNLAQYLINQTLLLARDSSKPQGKAHVDTLSRWSELTSPFDDSSASITMASFSSEECSPQGEWTILELETQH", "length": 1798, "header": "tr|A0ABI0NRG9-1|A0ABI0NRG9_BOVIN Isoform 1 of BTB/POZ domain-containing protein 8 OS=Bos taurus OX=9913 GN=BTBD8 PE=4 SV=1 CANONICAL=A0ABI0NRG9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NRG9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG9/entry#A0ABI0NRG9-1", "sequence": { "sequence": "MARCGEDSASPGVPLGSPGVCSKGLQRKGPCERRRLKAMVSEQLSQDLLRLLREEVHTDVTFSIGCTLFKAHKAVLLARVPDFYFHTVGHTDNLKNHEHVTVENFEASEFRTFLQIVYSSNRNIKSYEEEILRKKIVESGVPQKKCDFSVGNCTDHDRRLSVEFLSKRSSDHSLLKHEIPKDINSKEENVISTDIYDLEPASELGEDLLKLYVKHCCPDIDIYVDGKSFKAHRAILSARSSYFAAMLSGCWAESSQECVTLQSISHVEMNVMMHFIYGGTLDFPVKANVGQILNMADMYGLEGLKEVAIYILRRDYCNFFQKPVSRRLASILECLIIAHSVGVESLFADCMKWIVKHFARFWSERSFANVPPEIQKSCFNMLIHSLNDKNAAFLLMESDRLIVSLPRVKWTESALIMASQLQEECIAFIIENFSKIIQSENFALLLQSQAMSSTSDLLDKIFKAVEENITTENSCSLLMALDTLLNSDSTKEMGFTCKIQALRDKLWIFLVQSFYAVRHTESWKLMSTDDQQKIQAAAFDKGDDRRLGKKPIFSSSQQRKQVSDCGAIKNKSAGGSNKKQCLSYLSAHQKMKSDGLGASGHSSSTNRNSINKTLKHDDLKEKDPKPASKSTKELKTVEKNVSGKPKAIIKPKTENSDNAKSTNLSPRQAVERSATAAANEQKNSGNGKGVRNQEEQITGARPKVLTGNLNVQAKAKPLKKVTGKDSPHLRMAGPSSRSTNSSMELLTSTDSLDEPKENGSMKEKLPGHKPSSCDSRGQTVKNSVEGIKTSTVAMKYRPVSKDTNGISNKKSTHEQESNTHNSVLKKITSKGYSDPVPQAILKKRGNGNGCATAPQRTKNATANLAKTQGSQGSPNSVKSSVSSRQSDENVTKLDHSVTTDKQTPKRKIVKQGQTTLPKIGAKKVTMPKNPNQPKRGENLNNKDAKPKTLPEQVILKTLPSSQRPLKSEPSVVQKSVSLDVCDNNNKGSVSEQKPHEPLTNLTAKTSDAEAFQSPCILDSQKTLNNQEKQKLVLECQNISNLDKLIKRELESKQICSVKSETNVSGHKKIDHCTTAKIPCHSDETDNVDPKFYSTTALKSMISNPKENSLNSNPVCDLDSAHVEQLHSELDRKKQVGRKDTNQKLSIKCVKDVLPWVPEKTNGTLNSGQDDRKSKIHVEEQTVPSQLSDDSAMNEDNHATVESHISSKCFLEQISGKNSKDTETTETSESHETPEAPFMSHWNLSTNVLHQRESPESDSGSVTTSSDDIKPRSEDYDAGGSQDDDGSNDRGVSKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQGSSDLFQVNSTSDDEIPRKRPEIWSRSTIVHPREKENIPRGSVQFVQEVDQVSSSADETEDERSEAENVAENFSTSNPALQQFQGIINLAFEDATENESHEFRVTKSFKRSVLLSVDECEEIGSDEGEVHALFQPSVDSLSPSDVFDGISHEHHGRTCYSRYSHGSEGGVLECRQKKSNTIYKNKSFPLGLSSVDSSRKDKQSASATEKKGTTDVLSKGGIQLPPGDKVCSGSNVDNDFETHSKFSDSDIKSQERPCHLELRQRESNSDIPKNSFTKSLDSCRSQVLPQEGQVKESHSTATEKANIALSAGDIDGCDTVAQIYMYDHRPSKTLSPIYEMDVTEAFEQKMESETQGTDMDFEDEQHFAKQDWTLLKQLLSEQDSNLNITNSVPEDLNLAQYLINQTLLLARDSSKPQGKAHVDTLSRWSELTSPFDDSSASITMASFSSEECSPQGEWTILELETQH", "length": 1798, "header": "tr|A0ABI0NRG9-1|A0ABI0NRG9_BOVIN Isoform 1 of BTB/POZ domain-containing protein 8 OS=Bos taurus OX=9913 GN=BTBD8 PE=4 SV=1 CANONICAL=A0ABI0NRG9-1" }, "locus": { "chromosome": "3", "start_pos": 51316739, "end_pos": 51223916, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141207.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141207.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106239.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106239.1" } ] } }, { "isoform_ac": "A0ABI0NRJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG9/entry#A0ABI0NRJ4-1", "sequence": { "sequence": "MARCGEDSASPGVPLGSPGVCSKGLQRKGPCERRRLKAMVSEQLSQDLLRIVYSSNRNIKSYEEEILRKKIVESGVPQKKCDFSVGNCTDHDRRLSVEFLSKRSSDHSLLKHEIPKDINSKEENVISTDIYDLEPASELGEDLLKLYVKHCCPDIDIYVDGKSFKAHRAILSARSSYFAAMLSGCWAESSQECVTLQSISHVEMNVMMHFIYGGTLDFPVKANVGQILNMADMYGLEGLKEVAIYILRRDYCNFFQKPVSRRLASILECLIIAHSVGVESLFADCMKWIVKHFARFWSERSFANVPPEIQKSCFNMLIHSLNDKNAAFLLMESDRLIVSLPRVKWTESALIMASQLQEECIAFIIENFSKIIQSENFALLLQGFTCKIQALRDKLWIFLVQSFYAVRHTESWKLMSTDDQQKIQAAAFDKGDDRRLGKKPIFSSSQQRKQVSDCGAIKNKSAGGSNKKQCLSYLSAHQKMKSDGLGASGHSSSTNRNSINKTLKHDDLKEKDPKPASKSTKELKTVEKNVSGKPKAIIKPKTENSDNAKSTNLSPRQAVERSATAAANEQKNSGNGKGVRNQEEQITGARPKVLTGNLNVQAKAKPLKKVTGKDSPHLRMAGPSSRSTNSSMELLTSTDSLDEPKENGSMKEKLPGHKPSSCDSRGQTVKNSVEGIKTSTVAMKYRPVSKDTNGISNKKSTHEQESNTHNSVLKKITSKGYSDPVPQAILKKRGNGNGCATAPQRTKNATANLAKTQGSQGSPNSVKSSVSSRQSDENVTKLDHSVTTDKQTPKRKIVKQGQTTLPKIGAKKVTMPKNPNQPKRGENLNNKDAKPKTLPEQVILKTLPSSQRPLKSEPSVVQKSVSLDVCDNNNKGSVSEQKPHEPLTNLTAKTSDAEAFQSPCILDSQKTLNNQEKQKLVLECQNISNLDKLIKRELESKQICSVKSETNVSGHKKIDHCTTAKIPCHSDETDNVDPKFYSTTALKSMISNPKENSLNSNPVCDLDSAHVEQLHSELDRKKQVGRKDTNQKLSIKCVKDVLPWVPEKTNGTLNSGQDDRKSKIHVEEQTVPSQLSDDSAMNEDNHATVESHISSKCFLEQISGKNSKDTETTETSESHETPEAPFMSHWNLSTNVLHQRESPESDSGSVTTSSDDIKPRSEDYDAGGSQDDDGSNDRGVSKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQGSSDLFQVNSTSDDEIPRKRPEIWSRSTIVHPREKENIPRGSVQFVQEVDQVSSSADETEDERSEAENVAENFSTSNPALQQFQGIINLAFEDATENESHEFRVTKSFKRSVLLSVDECEEIGSDEGEVHALFQPSVDSLSPSDVFDGISHEHHGRTCYSRYSHGSEGGVLECRQKKSNTIYKNKSFPLGLSSVDSSRKDKQSASATEKKGTTDVLSKGGIQLPPGDKVCSGSNVDNDFETHSKFSDSDIKSQERPCHLELRQRESNSDIPKNSFTKSLDSCRSQVLPQEGQVKESHSTATEKANIALSAGDIDGCDTVAQIYMYDHRPSKTLSPIYEMDVTEAFEQKMESETQGTDMDFEDEQHFAKQDWTLLKQLLSEQDSNLNITNSVPEDLNLAQYLINQTLLLARDSSKPQGKAHVDTLSRWSELTSPFDDSSASITMASFSSEECSPQGEWTILELETQH", "length": 1687, "header": "tr|A0ABI0NRJ4-1|A0ABI0NRJ4_BOVIN Computationally mapped isoform of BTB/POZ domain-containing protein 8 OS=Bos taurus OX=9913 GN=BTBD8 PE=4 SV=1 CANONICAL=A0ABI0NRG9-1" }, "locus": { "chromosome": "3", "start_pos": 51316739, "end_pos": 51223916, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151111.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151111.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105329.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105329.1" } ] } }, { "isoform_ac": "E1BNE4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG9/entry#E1BNE4-1", "sequence": { "sequence": "MARCGEDSASPGVPLGSPGVCSKGLQRKGPCERRRLKAMVSEQLSQDLLRIVYSSNRNIKSYEEEILRKKIVESGVPQKKCDFSVGNCTDHDRRLSVEFLSKRSSDHSLLKHEIPKDINSKEENVISTDIYDLEPASELGEDLLKLYVKHCCPDIDIYVDGKSFKAHRAILSARSSYFAAMLSGCWAESSQECVTLQSISHVEMNVMMHFIYGGTLDFPVKANVGQILNMADMYGLEGLKEVAIYILRRDYCNFFQKPVSRRLASILECLIIAHSVGVESLFADCMKWIVKHFARFWSERSFANVPPEIQKSCFNMLIHSLNDKNAAFLLMESDRLIVSLPRVKWTESALIMASQLQEECIAFIIENFSKIIQSENFALLLQSQAMSSTSDLLDKIFKAVEENITTENSCSLLMALDTLLNSDSTKEMGFTCKIQALRDKLWIFLVQSFYAVRHTESWKLMSTDDQQKIQAAAFDKGDDRRLGKKPIFSSSQQRKQVSDCGAIKNKSAGGSNKKQCLSYLSAHQKMKSDGLGASGHSSSTNRNSINKTLKHDDLKEKDPKPASKSTKELKTVEKNVSGKPKAIIKPKTENSDNAKSTNLSPRQAVERSATAAANEQKNSGNGKGVRNQEEQITGARPKVLTGNLNVQAKAKPLKKVTGKDSPHLRMAGPSSRSTNSSMELLTSTDSLDEPKENGSMKEKLPGHKPSSCDSRGQTVKNSVEGIKTSTVAMKYRPVSKDTNGISNKKSTHEQESNTHNSVLKKITSKGYSDPVPQAILKKRGNGNGCATAPQRTKNATANLAKTQGSQGSPNSVKSSVSSRQSDENVTKLDHSVTTDKQTPKRKIVKQGQTTLPKIGAKKVTMPKNPNQPKRGENLNNKDAKPKTLPEQVILKTLPSSQRPLKSEPSVVQKSVSLDVCDNNNKGSVSEQKPHEPLTNLTAKTSDAEAFQSPCILDSQKTLNNQEKQKLVLECQNISNLDKLIKRELESKQICSVKSETNVSGHKKIDHCTTAKIPCHSDETDNVDPKFYSTTALKSMISNPKENSLNSNPVCDLDSAHVEQLHSELDRKKQVGRKDTNQKLSIKCVKDVLPWVPEKTNGTLNSGQDDRKSKIHVEEQTVPSQLSDDSAMNEDNHATVESHISSKCFLEQISGKNSKDTETTETSESHETPEAPFMSHWNLSTNVLHQRESPESDSGSVTTSSDDIKPRSEDYDAGGSQDDDGSNDRGVSKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQGSSDLFQVNSTSDDEIPRKRPEIWSRSTIVHPREKENIPRGSVQFVQEVDQVSSSADETEDERSEAENVAENFSTSNPALQQFQGIINLAFEDATENESHEFRVTKSFKRSVLLSVDECEEIGSDEGEVHALFQPSVDSLSPSDVFDGISHEHHGRTCYSRYSHGSEGGVLECRQKKSNTIYKNKSFPLGLSSVDSSRKDKQSASATEKKGTTDVLSKGGIQLPPGDKVCSGSNVDNDFETHSKFSDSDIKSQERPCHLELRQRESNSDIPKNSFTKSLDSCRSQVLPQEGQVKESHSTATEKANIALSAGDIDGCDTVAQIYMYDHRPSKTLSPIYEMDVTEAFEQKMESETQGTDMDFEDEQHFAKQDWTLLKQLLSEQDSNLNITNSVPEDLNLAQYLINQTLLLARDSSKPQGKAHVDTLSRWSELTSPFDDSSASITMASFSSEECSPQGEWTILELETQH", "length": 1733, "header": "tr|E1BNE4-1|A0ABI0NRG9_BOVIN Computationally mapped isoform of BTB/POZ domain-containing protein 8 OS=Bos taurus OX=9913 GN=BTBD8 PE=4 SV=4 CANONICAL=A0ABI0NRG9-1" }, "locus": { "chromosome": "3", "start_pos": 51316739, "end_pos": 51223916, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008109.8", "url": "https://www.ensembl.org/id/ENSBTAT00000008109.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008109.7", "url": "https://www.ensembl.org/id/ENSBTAP00000008109.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1000, "end_pos": 1002, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1037, "end_pos": 1039, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1062, "end_pos": 1064, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1161, "end_pos": 1163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1242, "end_pos": 1244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1341, "end_pos": 1343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1404, "end_pos": 1406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1429, "end_pos": 1431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1516, "end_pos": 1518, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1718, "end_pos": 1720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1735, "end_pos": 1737, "annotation": "n_glycosylation_sequon" }, { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" }, { "start_pos": 640, "end_pos": 642, "annotation": "n_glycosylation_sequon" }, { "start_pos": 663, "end_pos": 665, "annotation": "n_glycosylation_sequon" }, { "start_pos": 740, "end_pos": 742, "annotation": "n_glycosylation_sequon" }, { "start_pos": 758, "end_pos": 760, "annotation": "n_glycosylation_sequon" }, { "start_pos": 859, "end_pos": 861, "annotation": "n_glycosylation_sequon" }, { "start_pos": 889, "end_pos": 891, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NRG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG9" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 126, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1000, "end_pos": 1002 }, { "start_pos": 1037, "end_pos": 1039 }, { "start_pos": 1062, "end_pos": 1064 }, { "start_pos": 1161, "end_pos": 1163 }, { "start_pos": 1242, "end_pos": 1244 }, { "start_pos": 1341, "end_pos": 1343 }, { "start_pos": 1404, "end_pos": 1406 }, { "start_pos": 1429, "end_pos": 1431 }, { "start_pos": 1516, "end_pos": 1518 }, { "start_pos": 152, "end_pos": 154 }, { "start_pos": 1718, "end_pos": 1720 }, { "start_pos": 1735, "end_pos": 1737 }, { "start_pos": 432, "end_pos": 434 }, { "start_pos": 468, "end_pos": 470 }, { "start_pos": 570, "end_pos": 572 }, { "start_pos": 611, "end_pos": 613 }, { "start_pos": 640, "end_pos": 642 }, { "start_pos": 663, "end_pos": 665 }, { "start_pos": 740, "end_pos": 742 }, { "start_pos": 758, "end_pos": 760 }, { "start_pos": 859, "end_pos": 861 }, { "start_pos": 889, "end_pos": 891 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NP81-1", "uniprot_ac": "A0ABI0NP81", "uniprot_id": "A0ABI0NP81_BOVIN", "mass": { "chemical_mass": 86035.0, "monoisotopic_mass": 86035.0 }, "refseq": {}, "gene_names": [ { "name": "ACAP1", "type": "recommended", "evidence": [ { "id": "A0ABI0NP81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81" } ] }, { "name": "KCTD11", "type": "recommended", "evidence": [ { "id": "A0ABI0NP81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81" } ] }, { "name": "ACAP1", "type": "synonym", "evidence": [ { "id": "A0ABI0NP81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81" } ] } ], "protein_names": [ { "name": "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NP81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81/entry#names_and_taxonomy" } ] }, { "name": "Centaurin-beta", "type": "synonym", "evidence": [ { "id": "A0ABI0NP81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81/entry#names_and_taxonomy" } ] }, { "name": "Cnt-b", "type": "synonym", "evidence": [ { "id": "A0ABI0NP81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1M9L1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9L1#function" }, { "database": "UniProtKB", "id": "ARBA00056671", "url": "https://www.uniprot.org/uniprotkb/ARBA00056671#function" }, { "database": "UniProtKB", "id": "A0ABI0NP81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81#function" } ] }, { "annotation": "GTPase-activating protein for the ADP ribosylation factor family.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1M9L1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9L1#function" }, { "database": "UniProtKB", "id": "RU369028", "url": "https://www.uniprot.org/uniprotkb/RU369028#function" }, { "database": "UniProtKB", "id": "A0ABI0NP81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ACAP1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81", "locus": { "chromosome": "19", "start_pos": 27051870, "end_pos": 27040225, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000064956", "url": "https://www.ensembl.org/id/ENSBTAG00000064956" } ] } } ], "crossref": [ { "id": "ENSBTAG00000010532", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010532", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08852", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08852", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13250", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "508582", "url": "https://www.ncbi.nlm.nih.gov/gene/508582", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "539167", "url": "https://www.ncbi.nlm.nih.gov/gene/539167", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539167", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539167", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1ME87", "url": "https://www.orthodb.org/?gene=F1ME87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23180", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23180", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23180:SF197", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23180:SF197", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16746", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16746", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19329", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19329", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1M9L1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9L1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NP81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NP81-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ME87", "url": "https://www.uniprot.org/uniprotkb/F1ME87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ME87-1", "url": "https://www.uniprot.org/uniprotkb/F1ME87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPCSSSGLRRRKPNNGNCQGSACTCSSTLQARGPTGPGAGLAEMTVKLDFEECLKDSPRFRASVELVEAEVSELETRLEKLLKLGNGLLESGRHYLAASRAFIVGICDLAHLGPPEPMMAECLDKFTQSLSHKLDSHAELLDATQHTLQRQIQTLVKEGLRSFREAGRDFWRGAESLEAALTHNAEVPRRRAQEAEEAGAALKVARAGYRGRALDYALQINVIEDKRKFDIMEFVLRLVEAQATHFQQGHEELSQLAQYRKELGGQLHQLVLNSAREKRDMEQRHVLLKQKELGGEEPEPSLKEGPGGLVMEGHLFKRASNAFKTWSRRWFTIQSNQLVYQKRYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSPSKSCLLQADSERLMQLWVSAVQSSIATAFSQARLDDSPRGLGQGSGHLAISSAATLGPGGLTRGREPGGVGHVAAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVVINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGPPRGHPPVPPKPGLIRPKPGSFRSKPEPPSEDLQSLHPGALLFRAAGHPPSLPTMADALAHGADVNWVNGGQENATPLIQATAANSLLACEFLLQNGANVNQVDNQGRGPLHHATILGHTGLACLFLKRGADLGVRDSEGRDPLTIAVETANADIVTLLRLAKMREADAAQGQAGDETYLDIFRDFSLMASDDPEKLSRRSHDLHTL", "length": 785, "header": "tr|A0ABI0NP81-1|A0ABI0NP81_BOVIN Isoform 1 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein OS=Bos taurus OX=9913 GN=ACAP1 PE=4 SV=1 CANONICAL=A0ABI0NP81-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M9L1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81/entry#A0A3Q1M9L1-1", "sequence": { "sequence": "MTVKLDFEECLKDSPRFRASVELVEAEVSELETRLEKLLKLGNGLLESGRHYLAASRAFIVGICDLAHLGPPEPMMAECLDKFTQSLSHKLDSHAELLDATQHTLQRQIQTLVKEGLRSFREAGRDFWRGAESLEAALTHNAEVPRRRAQEAEEAGAALKVARAGYRGRALDYALQINVIEDKRKFDIMEFVLRLVEAQATHFQQGHEELSQLAQYRKELGGQLHQLVLNSAREKRDMEQRHVLLKQKELGGEEPEPSLKEGPGGLVMEGHLFKRASNAFKTWSRRWFTIQSNQLVYQKRYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSPSKSCLLQADSERLMQLWVSAVQSSIATAFSQARLDDSPRGLGQGSGHLAISSAATLGPGGLTRGREPGGVGHVAAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVVINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGPPRGHPPVPPKPGLIRPKPGSFRSKPEPPSEDLQSLHPGALLFRAAGHPPSLPTMADALAHGADVNWVNGGQENATPLIQATAANSLLACEFLLQNGANVNQVDNQGRGPLHHATILGHTGLACLFLKRGADLGVRDSEGRDPLTIAVETANADIVTLLRLAKMREADAAQGQAGDETYLDIFRDFSLMASDDPEKLSRRSHDLHTL", "length": 741, "header": "tr|A0A3Q1M9L1-1|A0ABI0NP81_BOVIN Computationally mapped isoform of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein OS=Bos taurus OX=9913 GN=ACAP1 PE=4 SV=3 CANONICAL=A0ABI0NP81-1" }, "locus": { "chromosome": "19", "start_pos": 27051785, "end_pos": 27040412, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081340.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081340.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070673.3", "url": "https://www.ensembl.org/id/ENSBTAP00000070673.3" } ] } }, { "isoform_ac": "A0ABI0NP81-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81/entry#A0ABI0NP81-1", "sequence": { "sequence": "MKPCSSSGLRRRKPNNGNCQGSACTCSSTLQARGPTGPGAGLAEMTVKLDFEECLKDSPRFRASVELVEAEVSELETRLEKLLKLGNGLLESGRHYLAASRAFIVGICDLAHLGPPEPMMAECLDKFTQSLSHKLDSHAELLDATQHTLQRQIQTLVKEGLRSFREAGRDFWRGAESLEAALTHNAEVPRRRAQEAEEAGAALKVARAGYRGRALDYALQINVIEDKRKFDIMEFVLRLVEAQATHFQQGHEELSQLAQYRKELGGQLHQLVLNSAREKRDMEQRHVLLKQKELGGEEPEPSLKEGPGGLVMEGHLFKRASNAFKTWSRRWFTIQSNQLVYQKRYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSPSKSCLLQADSERLMQLWVSAVQSSIATAFSQARLDDSPRGLGQGSGHLAISSAATLGPGGLTRGREPGGVGHVAAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVVINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGPPRGHPPVPPKPGLIRPKPGSFRSKPEPPSEDLQSLHPGALLFRAAGHPPSLPTMADALAHGADVNWVNGGQENATPLIQATAANSLLACEFLLQNGANVNQVDNQGRGPLHHATILGHTGLACLFLKRGADLGVRDSEGRDPLTIAVETANADIVTLLRLAKMREADAAQGQAGDETYLDIFRDFSLMASDDPEKLSRRSHDLHTL", "length": 785, "header": "tr|A0ABI0NP81-1|A0ABI0NP81_BOVIN Isoform 1 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein OS=Bos taurus OX=9913 GN=ACAP1 PE=4 SV=1 CANONICAL=A0ABI0NP81-1" }, "locus": { "chromosome": "19", "start_pos": 27051785, "end_pos": 27039571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150839.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150839.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107661.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107661.1" } ] } }, { "isoform_ac": "F1ME87-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81/entry#F1ME87-1", "sequence": { "sequence": "MLGAMFRAGTPMTPNLNPEGGGHYFIDRDGKAFRHILNFLRLGRLDLPLGYGETALLRAEADFYQIRPLLDALRELEASRGTPAPTAALLHADVDSSPRLVHFSARRGPHHYELSSVQVDTFRANLFCTDPECLGALRARFGVTNEDRAEGGPHFRLEWAPRPAELPEVEYRRLGLQPLWTGAPGEPREVVGTPSFLEEVLRVALEHGFRLDSVFPDPEDLLNSRSLRFVRH", "length": 232, "header": "tr|F1ME87-1|A0ABI0NP81_BOVIN Computationally mapped isoform of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein OS=Bos taurus OX=9913 GN=ACAP1 PE=4 SV=4 CANONICAL=A0ABI0NP81-1" }, "locus": { "chromosome": "19", "start_pos": 27054015, "end_pos": 27053320, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013923.6", "url": "https://www.ensembl.org/id/ENSBTAT00000013923.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013923.6", "url": "https://www.ensembl.org/id/ENSBTAP00000013923.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 36, "start_aa": "Thr", "end_pos": 36, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr36", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:539167", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539167", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NP81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81" }, { "id": "PS50115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arf-GAP", "eco_id": "ECO_0000259", "start_pos": 449, "end_pos": 571, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NP81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP81" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 309, "end_pos": 404, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 36 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 652, "end_pos": 654 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NT20-1", "uniprot_ac": "A0ABI0NT20", "uniprot_id": "A0ABI0NT20_BOVIN", "mass": { "chemical_mass": 40487.0, "monoisotopic_mass": 40487.0 }, "refseq": { "ac": "XP_005225905", "name": "L-seryl-tRNA(Sec) kinase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005225905" }, "gene_names": [ { "name": "PSTK", "type": "recommended", "evidence": [ { "id": "A0ABI0NT20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT20" } ] }, { "name": "PSTK", "type": "synonym", "evidence": [ { "id": "XP_005225905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005225905" } ] } ], "protein_names": [ { "name": "L-seryl-tRNA(Sec) kinase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005225905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005225905" } ] }, { "name": "Phosphoseryl-tRNA kinase", "type": "synonym", "evidence": [ { "id": "A0ABI0NT20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT20/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT20", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT20" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PSTK", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT20", "locus": { "chromosome": "26", "start_pos": 42780839, "end_pos": 42767455, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014028", "url": "https://www.ensembl.org/id/ENSBTAG00000014028" } ] } } ], "crossref": [ { "id": "ENSBTAG00000014028", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014028", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "511744", "url": "https://www.ncbi.nlm.nih.gov/gene/511744", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MQB7", "url": "https://www.orthodb.org/?gene=F1MQB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": 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[ "Protein" ] }, { "id": "F1MQB7-1", "url": "https://www.uniprot.org/uniprotkb/F1MQB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKMGEDVRGAHSERPQKLVLCVLCGLPAAGKSTFARALRHWLQQELGWAVGVVAYDDVMPEAVLEKPSQWKLFRQELLKFLEHFLLAVINGCQMSAPPSKTEAMWKDFITCLKDQDLISSAAVEAQALYPLTKTAVSRPLLLILDDNFYYQSMRYEVYQLARKYSSGFCQLFLDCALETCLQRNAQRPRPLPAETIHQMGNKIEKPNPEKNAWEHHSLAVQSPACASEARLKLTDLLITALENPIKHVEENLEQKETDRLIGSTNILHQADQTLRRIVSQTMKEAKDEQMFPYNLKLLAEELNKLKAEFLEDLRQGNKKYLCFQQTIDLADVISFFHYEKDNIVRKYFSKQH", "length": 352, "header": "tr|A0ABI0NT20-1|A0ABI0NT20_BOVIN Isoform 1 of Phosphoseryl-tRNA kinase OS=Bos taurus OX=9913 GN=PSTK PE=4 SV=1 CANONICAL=A0ABI0NT20-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NT20-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT20/entry#A0ABI0NT20-1", "sequence": { "sequence": "MKMGEDVRGAHSERPQKLVLCVLCGLPAAGKSTFARALRHWLQQELGWAVGVVAYDDVMPEAVLEKPSQWKLFRQELLKFLEHFLLAVINGCQMSAPPSKTEAMWKDFITCLKDQDLISSAAVEAQALYPLTKTAVSRPLLLILDDNFYYQSMRYEVYQLARKYSSGFCQLFLDCALETCLQRNAQRPRPLPAETIHQMGNKIEKPNPEKNAWEHHSLAVQSPACASEARLKLTDLLITALENPIKHVEENLEQKETDRLIGSTNILHQADQTLRRIVSQTMKEAKDEQMFPYNLKLLAEELNKLKAEFLEDLRQGNKKYLCFQQTIDLADVISFFHYEKDNIVRKYFSKQH", "length": 352, "header": "tr|A0ABI0NT20-1|A0ABI0NT20_BOVIN Isoform 1 of Phosphoseryl-tRNA kinase OS=Bos taurus OX=9913 GN=PSTK PE=4 SV=1 CANONICAL=A0ABI0NT20-1" }, "locus": { "chromosome": "26", "start_pos": 42780765, "end_pos": 42767654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152880.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152880.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106297.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106297.1" } ] } }, { "isoform_ac": "F1MQB7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT20/entry#F1MQB7-1", "sequence": { "sequence": "MKMGEDVRGAHSERPQKLVLCVLCGLPAAGKSTFARALRHWLQQELGWAVGVVAYDDVMPEAVLEKASASPLPSQWKLFRQELLKFLEHFLLAVINGCQMSAPPSKTEAMWKDFITCLKDQDLISSAAVEAQALYPLTKTAVSRPLLLILDDNFYYQSMRYEVYQLARKYSSGFCQLFLDCALETCLQRNAQRPRPLPAETIHQMGNKIEKPNPEKNAWEHHSLAVQSPACASEARLKLTDLLITALENPIKHVEENLEQKETDRLIGSTNILHQADQTLRRIVSQTMKEAKDSSPPGSPVLGTLQARTLEWVAISFS", "length": 318, "header": "tr|F1MQB7-1|A0ABI0NT20_BOVIN Computationally mapped isoform of Phosphoseryl-tRNA kinase OS=Bos taurus OX=9913 GN=PSTK PE=4 SV=5 CANONICAL=A0ABI0NT20-1" }, "locus": { "chromosome": "26", "start_pos": 42778432, "end_pos": 42767654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018631.8", "url": "https://www.ensembl.org/id/ENSBTAT00000018631.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018631.8", "url": "https://www.ensembl.org/id/ENSBTAP00000018631.8" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": 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"MQATSMLYSPAETVFDRGIAARISQNRLKAKGMGQHHNAQNYNNQSFEELRALCLRRGELFEDPFFPAEPTSLGFKELAPNSKHVQNISWQRPSQITSNPQFIVNGVSPTDICQGVLGDCWLLAAIGSLTAYPKLLSRVVPKGQSFKKNYAGIFHFQIWQFGEWMDVVVDDRLPTKNGKLVFVHSAERTEFWSALLEKAYAKLNGSYEALSGGNTVEGFEDFTGGVTQSFQLQNPPRNLQRILRKAVERSSLMGCSIEVTHEHELESLTQGMLVRGHAYSVTGLQDVSYQGRTETLIRVRNPWGRIEWNGAWSDNAKEWEEVAPDVQRQLLHRKEDGEFWMSYQDFLGNFTLLEICNVIPDTLSGDYKSCWHTTFYEGSWRRGSTAGGCRSYLDTFWTNPQFKICLPEKDDDIEDDEAVCTCLVALMQKNWRRTRPHGAQLETIGFVIYSIPKEFQNLQDVHLKKDFFVKYQDLGFSEIFTNSREVSSQFQLPPGEYIIIPSTFEPHKDADFLLRVFTEKHSESWELDEANYAELLQEESISETDIDQDFVRLFHIVAGGEGKEIGMYELQKLLNKVVSRFKNFKTKGFSLDVCRCMVNLLDKDGSGKLGLREFQVLWRKIKKWTDIFRECDQDQSGTLNSYEMRLAVEKAGIKLNNKVTQVLVARYANDSLIMEFDSFISCFLRLKAMFTYFLTMDPENTGQISLDLNQASSGWIYSTVSSLSKYISLQTGISISGTAAVSEFKSPTGVSQS", "length": 753, "header": "tr|A0ABI0NSL4-1|A0ABI0NSL4_BOVIN Isoform 1 of Calcium-activated neutral proteinase 11 OS=Bos taurus OX=9913 GN=CAPN11 PE=3 SV=1 CANONICAL=A0ABI0NSL4-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NSL4-1", "url": 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SV=1 CANONICAL=A0ABI0NSL4-1" }, "locus": { "chromosome": "23", "start_pos": 17705965, "end_pos": 17687224, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153641.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153641.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105953.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105953.1" } ] } }, { "isoform_ac": "F1MXQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSL4/entry#F1MXQ5-1", "sequence": { "sequence": "MLYSPVSETTENMGRWGDRPWGPGGETVFDRGIAARISQNRLKAKGMGQHHNAQNYNNQSFEELRALCLRRGELFEDPFFPAEPTSLGFKELAPNSKHVQNISWQRPSQITSNPQFIVNGVSPTDICQGVLGDCWLLAAIGSLTAYPKLLSRVVPKGQSFKKNYAGIFHFQIWQFGEWMDVVVDDRLPTKNGKLVFVHSAERTEFWSALLEKAYAKLNGSYEALSGGNTVEGFEDFTGGVTQSFQLQNPPRNLQRILRKAVERSSLMGCSIEVTHEHELESLTQGMLVRGHAYSVTGLQDVSYQGRTETLIRVRNPWGRIEWNGAWSDNAKEWEEVAPDVQRQLLHRKEDGEFWMSYQDFLGNFTLLEICNVIPDTLSGDYKSCWHTTFYEGSWRRGSTAGGCRSYLDTFWTNPQFKICLPEKDDDIEDDEAVCTCLVALMQKNWRRTRPHGAQLETIGFVIYSIPKEFQNLQDVHLKKDFFVKYQDLGFSEIFTNSREVSSQFQLPPGEYIIIPSTFEPHKDADFLLRVFTEKHSESWELDEANYAELLQEESISETDIDQDFVRLFHIVAGGEGKEIGMYELQKLLNKVVSRFKNFKTKGFSLDVCRCMVNLLDKDGSGKLGLREFQVLWRKIKKWTDIFRECDQDQSGTLNSYEMRLAVEKAGIKLNNKVTQVLVARYANDSLIMEFDSFISCFLRLKAMFTYFLTMDPENTGQISLDLNQWLQITMWG", "length": 732, "header": "tr|F1MXQ5-1|A0ABI0NSL4_BOVIN Computationally mapped isoform of Calcium-activated neutral proteinase 11 OS=Bos taurus OX=9913 GN=CAPN11 PE=3 SV=4 CANONICAL=A0ABI0NSL4-1" }, "locus": { "chromosome": "23", "start_pos": 17704914, "end_pos": 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"mass": { "chemical_mass": 78056.0, "monoisotopic_mass": 78056.0 }, "refseq": { "ac": "NP_001417649", "name": "protein-arginine deiminase type-2 isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417649" }, "gene_names": [ { "name": "PADI2", "type": "recommended", "evidence": [ { "id": "A0ABI0NS39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39" } ] }, { "name": "PADI2", "type": "synonym", "evidence": [ { "id": "NP_001417649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417649" } ] } ], "protein_names": [ { "name": "Protein-arginine deiminase", "type": "recommended", "evidence": [ { "id": "A0ABI0NS39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39/entry#names_and_taxonomy" } ] }, { "name": "3.5.3.15", "type": "synonym", "evidence": [ { "id": "A0ABI0NS39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39/entry#names_and_taxonomy" } ] }, { 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"url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39#function" } ] }, { "annotation": "Results describe the role of peptidyl arginine deiminase and arginine metabolism in the formation of amyloid fibrils from beta-amyloid peptides", "evidence": [ { "database": "RefSeq", "id": "NP_001417649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417649" }, { "database": "PubMed", "id": "20224908", "url": "https://glygen.org/publication/PubMed/20224908" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS39", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PADI2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39", "locus": { "chromosome": "2", "start_pos": 135528195, "end_pos": 135473434, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003403", "url": "https://www.ensembl.org/id/ENSBTAG00000003403" } ] } } ], "crossref": [ { "id": "ENSBTAG00000003403", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003403", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "617851", "url": "https://www.ncbi.nlm.nih.gov/gene/617851", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013530", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013530", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036556", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036556", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038685", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038685", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N048", "url": "https://www.orthodb.org/?gene=F1N048", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10837", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10837", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10837:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10837:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03068", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03068", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08526", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08526", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08527", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08527", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3247509", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3247509", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001417649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417649", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "18089", "url": "https://www.rhea-db.org/rhea/18089", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SRB9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SRB9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS39", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS39-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N048", "url": "https://www.uniprot.org/uniprotkb/F1N048", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N048-1", "url": "https://www.uniprot.org/uniprotkb/F1N048-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRERTVRLQYGSRVEAVYVLGTQLWTDVYSAAPAGAQTFGLKHSERVRVEVVRDGQAEEVATNGKQRWPLSPSTTLRLTMSQASPEASSDKVTVSYYEEEGITPVDQAGLFLTAIEISLDVDADRDGVVEKNNPRKASWTWGPEGQGAILLVNCDRDTPWLPQEDCSDEKVYSKEDLKDMSQMILRTKGPEHLPAGYEIVLYISMSDSDKVGVFCVETLQGIKKLLLELPRVLPPCVWQYPFFGQRYVHILGRRKLYHVVKYSGGSEELLFFVEGLRFPDEGFAGLVSIHVSLLEYMAEEIPLTPVFTDTVTFRIAPWIMTPNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYMNRGDRWIQDEIEFGYIEAPHKGFPVVLDSPRDGNLKDFPVKQLLGPDFGYVTREPLFETVTSLDSFGNLEVSPPVTVDGKTYPLGRILIGSSFPLSGGRRMTRVVRDFLQAQQVQVPVELYSDWLTVGHVDEFVTFVPIPGTKKFRMLMASTSACYKLFREKQKEGHGEAIMFKGLGGMSSKRITINKILSNESLVQENQYFQRCLDWNRDILKKELGLTEQDIIDLPALFKMDKNHQARAFFPNMVNMIVLDKDLGIPKPFGPQVEEVCCLETHVRCLLEPLGLCCTFVDDISAYHKFLGEVHCGTNVRRKPFAFKWWHMEP", "length": 687, "header": "tr|A0ABI0NS39-1|A0ABI0NS39_BOVIN Isoform 1 of Protein-arginine deiminase OS=Bos taurus OX=9913 GN=PADI2 PE=3 SV=1 CANONICAL=A0ABI0NS39-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SRB9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39/entry#A0AAA9SRB9-1", "sequence": { "sequence": "MLRERTVRLQYGSRVEAVYVLGTQLWTDVYSAAPAGAQTFGLKHSERVRVEVVRDGQAEEVATNGKQRWPLSPSTTLRLTMSQASPEASSDKVTVSYYEEEGITPVDQAGLFLTAIEISLDVDADRDGVVEKNNPRKASWTWGPEGQGAILLVNCDRDTPWLPQEDCSDEKVYSKEDLKDMSQMILRTKGPEHLPAGYEIVLYISMSDSDKVGVFCVENPFFGQRYVHILGRRKLYHVVKYSGGSEELLFFVEGLRFPDEGFAGLVSIHVSLLEYMAETGVKSTLTRPPDLSHAQEIPLTPVFTDTVTFRIAPWIMTPNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYMNRGDRWIQDEIEFGYIEAPHKGFPVVLDSPRDGNLKDFPVKQLLGPDFGYVTREPLFETVTSLDSFGNLEVSPPVTVDGKTYPLGRILIGSSFPLSGGRRMTRVVRDFLQAQQVQVPVELYSDWLTVGHVDEFVTFVPIPGTKKFRMLMASTSACYKLFREKQKEGHGEAIMFKGLGGMSSKRITINKILSNESLVQENQYFQRCLDWNRDILKKELGLTEQDIIDLPALFKMDKNHQARAFFPNMVNMIVLDKDLGIPKPFGPQVEEVCCLETHVRCLLEPLGLCCTFVDDISAYHKFLGEVHCGTNVRRKPFAFKWWHMEP", "length": 682, "header": "tr|A0AAA9SRB9-1|A0ABI0NS39_BOVIN Computationally mapped isoform of Protein-arginine deiminase OS=Bos taurus OX=9913 GN=PADI2 PE=3 SV=1 CANONICAL=A0ABI0NS39-1" }, "locus": { "chromosome": "2", "start_pos": 135527191, "end_pos": 135473514, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135868.2", "url": "https://www.ensembl.org/id/ENSBTAT00000135868.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086522.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086522.1" } ] } }, { "isoform_ac": "A0ABI0NS39-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39/entry#A0ABI0NS39-1", "sequence": { "sequence": "MLRERTVRLQYGSRVEAVYVLGTQLWTDVYSAAPAGAQTFGLKHSERVRVEVVRDGQAEEVATNGKQRWPLSPSTTLRLTMSQASPEASSDKVTVSYYEEEGITPVDQAGLFLTAIEISLDVDADRDGVVEKNNPRKASWTWGPEGQGAILLVNCDRDTPWLPQEDCSDEKVYSKEDLKDMSQMILRTKGPEHLPAGYEIVLYISMSDSDKVGVFCVETLQGIKKLLLELPRVLPPCVWQYPFFGQRYVHILGRRKLYHVVKYSGGSEELLFFVEGLRFPDEGFAGLVSIHVSLLEYMAEEIPLTPVFTDTVTFRIAPWIMTPNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYMNRGDRWIQDEIEFGYIEAPHKGFPVVLDSPRDGNLKDFPVKQLLGPDFGYVTREPLFETVTSLDSFGNLEVSPPVTVDGKTYPLGRILIGSSFPLSGGRRMTRVVRDFLQAQQVQVPVELYSDWLTVGHVDEFVTFVPIPGTKKFRMLMASTSACYKLFREKQKEGHGEAIMFKGLGGMSSKRITINKILSNESLVQENQYFQRCLDWNRDILKKELGLTEQDIIDLPALFKMDKNHQARAFFPNMVNMIVLDKDLGIPKPFGPQVEEVCCLETHVRCLLEPLGLCCTFVDDISAYHKFLGEVHCGTNVRRKPFAFKWWHMEP", "length": 687, "header": "tr|A0ABI0NS39-1|A0ABI0NS39_BOVIN Isoform 1 of Protein-arginine deiminase OS=Bos taurus OX=9913 GN=PADI2 PE=3 SV=1 CANONICAL=A0ABI0NS39-1" }, "locus": { "chromosome": "2", "start_pos": 135527191, "end_pos": 135473514, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137667.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137667.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106660.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106660.1" } ] } }, { "isoform_ac": "F1N048-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39/entry#F1N048-1", "sequence": { "sequence": "MLRERTVRLQYGSRVEAVYVLGTQLWTDVYSAAPAGAQTFGLKHSERVRVEVVRDGQAEEVATNGKQRWPLSPSTTLRLTMSQASPEASSDKVTVSYYEEEGITPVDQAGLFLTAIEISLDVDADRDGVVEKNNPRKASWTWGPEGQGAILLVNCDRDTPWLPQEDCSDEKVYSKEDLKDMSQMILRTKGPEHLPAGYEIVLYISMSDSDKVGVFCVENPFFGQRYVHILGRRKLYHVVKYSGGSEELLFFVEGLRFPDEGFAGLVSIHVSLLEYMAEEIPLTPVFTDTVTFRIAPWIMTPNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYMNRGDRWIQDEIEFGYIEAPHKGFPVVLDSPRDGNLKDFPVKQLLGPDFGYVTREPLFETVTSLDSFGNLEVSPPVTVDGKTYPLGRILIGSSFPLSGGRRMTRVVRDFLQAQQVQVPVELYSDWLTVGHVDEFVTFVPIPGTKKFRMLMASTSACYKLFREKQKEGHGEAIMFKVACGSSGHGVGHFKWHQPRGELNGSKPKCHLHSGTLRFGNEAREERTSCSLGAGRRAELTTQCRTASPRVPERETVCLIQTRN", "length": 599, "header": "tr|F1N048-1|A0ABI0NS39_BOVIN Computationally mapped isoform of Protein-arginine deiminase OS=Bos taurus OX=9913 GN=PADI2 PE=3 SV=3 CANONICAL=A0ABI0NS39-1" }, "locus": { "chromosome": "2", "start_pos": 135523040, "end_pos": 135473514, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004411.8", "url": "https://www.ensembl.org/id/ENSBTAT00000004411.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004411.7", "url": "https://www.ensembl.org/id/ENSBTAP00000004411.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Arginine metabolising enzymes as therapeutic tools for Alzheimer's disease: peptidyl arginine deiminase catalyses fibrillogenesis of beta-amyloid peptides.", "journal": "Molecular neurobiology", "date": "2010-06", "authors": "Mohlake Peter, Whiteley Chris G", "evidence": [ { "database": "RefSeq", "id": "NP_001417649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417649" } ], "reference": [ { "type": "PubMed", "id": "20224908", "url": "https://glygen.org/publication/PubMed/20224908" } ] } ], "pathway": [ { "id": "R-BTA-3247509", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3247509", "resource": "Reactome", "description": "Chromatin modifying enzymes" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein-arginine deiminase activity", "id": "GO:0004668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004668", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS39", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS39", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39" } ], "pmid": "" }, { "name": "histone arginine deiminase activity", "id": "GO:0140794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140794", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS39", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS39", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS39", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS39", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "18089", "name": "", "equation": "L-arginyl-[protein] + H2O = L-citrullyl-[protein] + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BD46-1", "E1BCN3-1", "A0AAA9TGP5-1", "A0ABI0NS39-1" ], "evidence": [ { "id": "18089", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18089" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9TGP5", "gene_name": "PADI6", "activity": [ { "ec_number": "3.5.3.15", "activity": "L-arginyl-[protein] + H2O = L-citrullyl-[protein] + NH4(+).", "evidence": [ { "id": "A0AAA9TGP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGP5" } ] }, { "ec_number": "3.5.3.15", "activity": "", "evidence": [ { "id": "A0AAA9TGP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGP5" } ] } ] }, { "uniprot_ac": "A0ABI0NS39", "gene_name": "PADI2", "activity": [ { "ec_number": "3.5.3.15", "activity": "L-arginyl-[protein] + H2O = L-citrullyl-[protein] + NH4(+).", "evidence": [ { "id": "A0ABI0NS39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39" } ] }, { "ec_number": "3.5.3.15", "activity": "", "evidence": [ { "id": "A0ABI0NS39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39" } ] } ] }, { "uniprot_ac": "E1BCN3", "gene_name": "PADI4", "activity": [ { "ec_number": "3.5.3.15", "activity": "L-arginyl-[protein] + H2O = L-citrullyl-[protein] + NH4(+).", "evidence": [ { "id": "E1BCN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCN3" } ] }, { "ec_number": "3.5.3.15", "activity": "", "evidence": [ { "id": "E1BCN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCN3" } ] } ] }, { "uniprot_ac": "E1BD46", "gene_name": "PADI3", "activity": [ { "ec_number": "3.5.3.15", "activity": "L-arginyl-[protein] + H2O = L-citrullyl-[protein] + NH4(+).", "evidence": [ { "id": "E1BD46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BD46" } ] }, { "ec_number": "3.5.3.15", "activity": "", "evidence": [ { "id": "E1BD46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BD46" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NS39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39" }, { "id": "PF08526", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08526" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein-arginine deiminase (PAD) N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 114, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NS39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39" }, { "id": "PF08527", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08527" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein-arginine deiminase (PAD) central", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 296, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NS39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS39" }, { "id": "PF03068", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03068" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein-arginine deiminase C-terminal", "eco_id": "ECO_0000259", "start_pos": 307, "end_pos": 684, "start_aa": "Val", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.3.15", "ec_name": "L-arginyl-[protein] + H2O = L-citrullyl-[protein] + NH4(+).", "evidence": [ { "id": "3.5.3.15", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.3.15" }, { "id": "3.5.3.15", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.3.15" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 556, "end_pos": 558 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0ABI0NS47-1", "uniprot_ac": "A0ABI0NS47", "uniprot_id": "A0ABI0NS47_BOVIN", "mass": { "chemical_mass": 25716.0, "monoisotopic_mass": 25716.0 }, "refseq": {}, "gene_names": [ { "name": "CRCP", "type": "recommended", "evidence": [ { "id": "A0ABI0NS47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47" } ] } ], "protein_names": [ { "name": "DNA-directed RNA polymerase III subunit RPC9", "type": "recommended", "evidence": [ { "id": "A0ABI0NS47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47/entry#names_and_taxonomy" } ] }, { "name": "DNA-directed RNA polymerase III subunit rpc9", "type": "synonym", "evidence": [ { "id": "A0ABI0NS47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9T072", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T072#function" }, { "database": "UniProtKB", "id": "ARBA00043924", "url": "https://www.uniprot.org/uniprotkb/ARBA00043924#function" }, { "database": "UniProtKB", "id": "A0AAA9TN64", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TN64#function" }, { "database": "UniProtKB", "id": "A0AAA9TYI6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYI6#function" }, { "database": "UniProtKB", "id": "A0AAA9TIA6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIA6#function" }, { "database": "UniProtKB", "id": "A0AAF6ZJ37", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZJ37#function" }, { "database": "UniProtKB", "id": "A0ABI0NS47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47#function" } ] }, { "annotation": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III (Pol III) which synthesizes small non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs from at least 500 distinct genomic loci. With POLR3H/RPC8 forms a mobile stalk that protrudes from Pol III core and functions primarily in transcription initiation. Pol III plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-kappa-B through the RIG-I pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9T072", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T072#function" }, { "database": "UniProtKB", "id": "ARBA00045808", "url": "https://www.uniprot.org/uniprotkb/ARBA00045808#function" }, { "database": "UniProtKB", "id": "A0AAA9TN64", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TN64#function" }, { "database": "UniProtKB", "id": "A0AAA9TYI6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYI6#function" }, { "database": "UniProtKB", "id": "A0AAA9TIA6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIA6#function" }, { "database": "UniProtKB", "id": "A0AAF6ZJ37", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZJ37#function" }, { "database": "UniProtKB", "id": "A0ABI0NS47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CRCP", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47", "locus": { "chromosome": "25", "start_pos": 28036980, "end_pos": 27997740, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000037489", "url": "https://www.ensembl.org/id/ENSBTAG00000037489" } ] } } ], "crossref": [ { "id": "507533", "url": "https://www.ncbi.nlm.nih.gov/gene/507533", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038324", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038324", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15561", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15561", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15561:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15561:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9T072", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T072", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T072-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T072-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIA6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIA6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TN64", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TN64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TN64-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TN64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYI6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYI6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZJ37", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZJ37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZJ37-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZJ37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS47-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSQTLNILIPRQAKSIGVQMARGARPARGPAGVLQAPGVHRGDPGVHRGARSRLWGVRRGAGSRSFSAWSSACAGDPRRRGGEDMEVKDANAALLSNYEVFQLLTDLKEQRKESGKNKHSSGQQNLNTITYETLKYISKTPCKHQSPEIVREFLTAMKSHKLTKAEKLQLLNHRPVTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAGPEAEQQQNASDDVAMDEEDPA", "length": 233, "header": "tr|A0ABI0NS47-1|A0ABI0NS47_BOVIN Isoform 1 of DNA-directed RNA polymerase III subunit RPC9 OS=Bos taurus OX=9913 GN=CRCP PE=3 SV=1 CANONICAL=A0ABI0NS47-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T072-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47/entry#A0AAA9T072-1", "sequence": { "sequence": "MARGARPARGPAGVLQAPGVHRGDPGVHRGARSRLWGVRRGAGSRSFSAWSSACAGDPRRRGGEDMEVKDANAALLSNYETLKYISKTPCKHQSPEIVREFLTAMKSHKLTKAEKLQLLNHRPVTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAGPEAEQQQNASDDVAMDEEDPA", "length": 180, "header": "tr|A0AAA9T072-1|A0ABI0NS47_BOVIN Computationally mapped isoform of DNA-directed RNA polymerase III subunit RPC9 OS=Bos taurus OX=9913 GN=CRCP PE=3 SV=1 CANONICAL=A0ABI0NS47-1" }, "locus": { "chromosome": "25", "start_pos": 28036304, "end_pos": 28004377, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107029.2", "url": "https://www.ensembl.org/id/ENSBTAT00000107029.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089047.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089047.1" } ] } }, { "isoform_ac": "A0AAA9TIA6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47/entry#A0AAA9TIA6-1", "sequence": { "sequence": "MEVAEKLQLLNHRPVTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAGPEAEQQQNASDDVAMDEEDPA", "length": 71, "header": "tr|A0AAA9TIA6-1|A0ABI0NS47_BOVIN Computationally mapped isoform of DNA-directed RNA polymerase III subunit RPC9 OS=Bos taurus OX=9913 GN=CRCP PE=3 SV=1 CANONICAL=A0ABI0NS47-1" }, "locus": { "chromosome": "25", "start_pos": 28036304, "end_pos": 28004572, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092069.2", "url": "https://www.ensembl.org/id/ENSBTAT00000092069.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096644.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096644.1" } ] } }, { "isoform_ac": "A0AAA9TN64-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47/entry#A0AAA9TN64-1", "sequence": { "sequence": "MSTAGGRQRKDANAALLSNYEVFQLLTDLKEQRKESGKNKHSSGQQNLNTITYETLKYISKTPCKHQSPEIVREFLTAMKSHKLTKAEKLQLLNHRPVTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAGPEAEQQQNASDDVAMDEEDPA", "length": 154, "header": "tr|A0AAA9TN64-1|A0ABI0NS47_BOVIN Computationally mapped isoform of DNA-directed RNA polymerase III subunit RPC9 OS=Bos taurus OX=9913 GN=CRCP PE=3 SV=2 CANONICAL=A0ABI0NS47-1" }, "locus": { "chromosome": "25", "start_pos": 28036304, "end_pos": 28013192, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129009.2", "url": "https://www.ensembl.org/id/ENSBTAT00000129009.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097790.2", "url": "https://www.ensembl.org/id/ENSBTAP00000097790.2" } ] } }, { "isoform_ac": "A0AAA9TYI6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47/entry#A0AAA9TYI6-1", "sequence": { "sequence": "MYGLYCVEVFQLLTDLKEQRKESGKNKHSSGQQNLNTITYETLKYISKTPCKHQSPEIVREFLTAMKSHKLTKAEKLQLLNHRPVTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAGPEAEQQQNASDDVAMDEEDPA", "length": 141, "header": "tr|A0AAA9TYI6-1|A0ABI0NS47_BOVIN Computationally mapped isoform of DNA-directed RNA polymerase III subunit RPC9 OS=Bos taurus OX=9913 GN=CRCP PE=3 SV=2 CANONICAL=A0ABI0NS47-1" }, "locus": { "chromosome": "25", "start_pos": 28036304, "end_pos": 28017218, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123980.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123980.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101756.2", "url": "https://www.ensembl.org/id/ENSBTAP00000101756.2" } ] } }, { "isoform_ac": "A0AAF6ZJ37-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47/entry#A0AAF6ZJ37-1", "sequence": { "sequence": "MARGARPARGPAGVLQAPGVHRGDPGVHRGARSRLWGVRRGAGSRSFSAWSSACAGDPRRRGGEDMEVKDANAALLSNYEVFQLLTDLKEQRKESGKNKHSSGQQNLNTITYETLKYISKTPCKHQSPEIVREFLTAMKSHKLTKAEKLQLLNHRPVTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAGPEAEQQQNASDDVAMDEEDPA", "length": 213, "header": "tr|A0AAF6ZJ37-1|A0ABI0NS47_BOVIN Computationally mapped isoform of DNA-directed RNA polymerase III subunit RPC9 OS=Bos taurus OX=9913 GN=CRCP PE=3 SV=1 CANONICAL=A0ABI0NS47-1" }, "locus": { "chromosome": "25", "start_pos": 28036304, "end_pos": 28004377, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053944.4", "url": "https://www.ensembl.org/id/ENSBTAT00000053944.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048749.2", "url": "https://www.ensembl.org/id/ENSBTAP00000048749.2" } ] } }, { "isoform_ac": "A0ABI0NS47-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47/entry#A0ABI0NS47-1", "sequence": { "sequence": "MFSQTLNILIPRQAKSIGVQMARGARPARGPAGVLQAPGVHRGDPGVHRGARSRLWGVRRGAGSRSFSAWSSACAGDPRRRGGEDMEVKDANAALLSNYEVFQLLTDLKEQRKESGKNKHSSGQQNLNTITYETLKYISKTPCKHQSPEIVREFLTAMKSHKLTKAEKLQLLNHRPVTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAGPEAEQQQNASDDVAMDEEDPA", "length": 233, "header": "tr|A0ABI0NS47-1|A0ABI0NS47_BOVIN Isoform 1 of DNA-directed RNA polymerase III subunit RPC9 OS=Bos taurus OX=9913 GN=CRCP PE=3 SV=1 CANONICAL=A0ABI0NS47-1" }, "locus": { "chromosome": "25", "start_pos": 28036304, "end_pos": 28004317, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148710.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148710.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105670.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105670.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47" } ], "pmid": "" }, { "name": "RNA polymerase III complex", "id": "GO:0005666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005666", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NS47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS47" }, { "id": "SM00657", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00657" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNA polymerase Rpb4/RPC9 core", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 212, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 220, "end_pos": 222 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQQ4-1", "uniprot_ac": "A0ABI0NQQ4", "uniprot_id": "A0ABI0NQQ4_BOVIN", "mass": { "chemical_mass": 64006.0, "monoisotopic_mass": 64006.0 }, "refseq": { "ac": "XP_005221614", "name": "5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221614" }, "gene_names": [ { "name": "PRKAA1", "type": "recommended", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "name": "PRKAA1", "type": "synonym", "evidence": [ { "id": "XP_005221614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221614" } ] } ], "protein_names": [ { "name": "5'-AMP-activated protein kinase catalytic subunit alpha-1", "type": "recommended", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.26", "type": "synonym", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.31", "type": "synonym", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4/entry#names_and_taxonomy" } ] }, { "name": "5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005221614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221614" } ] }, { "name": "Acetyl-CoA carboxylase kinase", "type": "synonym", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4/entry#names_and_taxonomy" } ] }, { "name": "Hydroxymethylglutaryl-CoA reductase kinase", "type": "synonym", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4/entry#names_and_taxonomy" } ] }, { "name": "Tau-protein kinase PRKAA1", "type": "synonym", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRKAA1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4", "locus": { "chromosome": "20", "start_pos": 33703223, "end_pos": 33674814, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000013", "url": "https://www.ensembl.org/id/ENSBTAG00000000013" } ] } } ], "crossref": [ { "id": "ENSBTAG00000000013", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000013", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12199", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12199", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14079", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14079", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14403", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14403", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540404", "url": "https://www.ncbi.nlm.nih.gov/gene/540404", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MBG5", "url": "https://www.orthodb.org/?gene=F1MBG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346:SF87", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346:SF87", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16579", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16579", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1632852", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380972", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380972", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5628897", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5628897", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6804756", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804756", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9931269", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9931269", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005221614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221614", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12801", "url": "https://www.rhea-db.org/rhea/12801", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "20333", "url": "https://www.rhea-db.org/rhea/20333", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "23172", "url": "https://www.rhea-db.org/rhea/23172", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "53904", "url": "https://www.rhea-db.org/rhea/53904", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9T3X0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3X0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3X0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MBG5", "url": "https://www.uniprot.org/uniprotkb/F1MBG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MBG5-1", "url": "https://www.uniprot.org/uniprotkb/F1MBG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRACQRNDSDAEAQGKSSEASLTSSVTSLDSSPVELTPRPGSHTIEFFEMCANLIKILAQ", "length": 559, "header": "tr|A0ABI0NQQ4-1|A0ABI0NQQ4_BOVIN Isoform 1 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Bos taurus OX=9913 GN=PRKAA1 PE=3 SV=1 CANONICAL=A0ABI0NQQ4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T3X0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4/entry#A0AAA9T3X0-1", "sequence": { "sequence": "MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVERTGSMKELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRACQRNDSDAEAQGKSSEASLTSSVTSLDSSPVELTPRPGSHTIEFFEMCANLIKILAQ", "length": 574, "header": "tr|A0AAA9T3X0-1|A0ABI0NQQ4_BOVIN Computationally mapped isoform of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Bos taurus OX=9913 GN=PRKAA1 PE=3 SV=1 CANONICAL=A0ABI0NQQ4-1" }, "locus": { "chromosome": "20", "start_pos": 33700482, "end_pos": 33674838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090743.2", "url": "https://www.ensembl.org/id/ENSBTAT00000090743.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091349.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091349.1" } ] } }, { "isoform_ac": "A0ABI0NQQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4/entry#A0ABI0NQQ4-1", "sequence": { "sequence": "MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRACQRNDSDAEAQGKSSEASLTSSVTSLDSSPVELTPRPGSHTIEFFEMCANLIKILAQ", "length": 559, "header": "tr|A0ABI0NQQ4-1|A0ABI0NQQ4_BOVIN Isoform 1 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Bos taurus OX=9913 GN=PRKAA1 PE=3 SV=1 CANONICAL=A0ABI0NQQ4-1" }, "locus": { "chromosome": "20", "start_pos": 33700482, "end_pos": 33674838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137049.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137049.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104690.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104690.1" } ] } }, { "isoform_ac": "F1MBG5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4/entry#F1MBG5-1", "sequence": { "sequence": "MATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRDNRILVSQFIYTNYQH", "length": 206, "header": "tr|F1MBG5-1|A0ABI0NQQ4_BOVIN Computationally mapped isoform of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Bos taurus OX=9913 GN=PRKAA1 PE=3 SV=2 CANONICAL=A0ABI0NQQ4-1" }, "locus": { 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{ "id": "R-BTA-6804756", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804756", "resource": "Reactome", "description": "Regulation of TP53 Activity through Phosphorylation" }, { "id": "R-BTA-9931269", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9931269", "resource": "Reactome", "description": "AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 36, "go_terms": [ { "name": "negative regulation of hepatocyte apoptotic process", "id": "GO:1903944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903944", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of T cell mediated immune response to tumor cell", "id": "GO:0002842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002842", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of adipose tissue development", "id": "GO:1904179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904179", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "response to gamma radiation", "id": "GO:0010332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010332", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "neuron cellular homeostasis", "id": "GO:0070050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070050", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "cellular response to glucose stimulus", "id": "GO:0071333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071333", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of protein targeting to mitochondrion", "id": "GO:1903955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903955", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "negative regulation of lipid catabolic process", "id": "GO:0050995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050995", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "energy homeostasis", "id": "GO:0097009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097009", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "response to hydrogen peroxide", "id": "GO:0042542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042542", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process", "id": "GO:0006695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006695", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "regulation of vascular permeability", "id": "GO:0043114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043114", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "CAMKK-AMPK signaling cascade", "id": "GO:0061762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061762", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of T cell activation", "id": "GO:0050870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050870", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "regulation of microtubule cytoskeleton organization", "id": "GO:0070507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070507", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of protein localization", "id": "GO:1903829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "protein localization to lipid droplet", "id": "GO:1990044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990044", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "motor behavior", "id": "GO:0061744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061744", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "regulation of stress granule assembly", "id": "GO:0062028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062028", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial transcription", "id": "GO:1903109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903109", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "positive regulation of catabolic process", "id": "GO:0009896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009896", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "AMP-activated protein kinase activity", "id": "GO:0004679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004679", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity", "id": "GO:0047322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047322", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "histone H2BS36 kinase activity", "id": "GO:0140823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140823", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "nucleotide-activated protein kinase complex", "id": "GO:0031588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031588", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" }, { "name": "plasma membrane bounded cell projection", "id": "GO:0120025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120025", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12801", "name": "", "equation": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LJI4-1", "A0A3Q1NDU7-1", "P35508-1", "A0ABI0NQQ4-1", "G5E5D4-1", "A0AAA9T8T9-1" ], "evidence": [ { "id": "12801", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12801" } ] }, { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "20333", "name": "", "equation": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NQQ4-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "20333", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20333" } ] }, { "id": "23172", "name": "", "equation": "L-seryl-[3-hydroxy-3-methylglutaryl-coenzyme A reductase] + ATP = O-phospho-L-seryl-[3-hydroxy-3-methylglutaryl-coenzyme A reductase] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NQQ4-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "23172", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23172" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "53904", "name": "", "equation": "L-threonyl-[tau protein] + ATP = O-phospho-L-threonyl-[tau protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LJI4-1", "A0A3Q1NDU7-1", "P35508-1", "A0ABI0NQQ4-1", "G5E5D4-1", "A0AAA9T8T9-1" ], "evidence": [ { "id": "53904", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53904" } ] }, { "id": "R-BTA-1632857", "name": "ULK1 phosphorylates AMBRA1:BECN1 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SBK8-1", "A0ABI0NQQ4-1", "F1MTL5-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-1632857", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1632857" } ] }, { "id": "R-BTA-200421", "name": "Activation of cytosolic AMPK by phosphorylation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NQQ4-1", "E1BCU9-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-200421", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-200421" } ] }, { "id": "R-BTA-380927", "name": "p-AMPK phosphorylates TSC1:TSC2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NQQ4-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-380927", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380927" } ] }, { "id": "R-BTA-380930", "name": "Phosphorylated AMPK binds AMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NQQ4-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-380930", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380930" } ] }, { "id": "R-BTA-380949", "name": "AMPK is dephosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NQQ4-1", "A0AAA9SU81-1", "O62829-1" ], "evidence": [ { "id": "R-BTA-380949", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380949" } ] }, { "id": "R-BTA-447074", "name": "AMPK phosphorylates Raptor in the mTORC1 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3SX43-1", "A0ABI0NQQ4-1", "A0A3Q1MEZ6-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-447074", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-447074" } ] }, { "id": "R-BTA-5631941", "name": "SESN1,2,3 bind AMPK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q58CN8-1", "A0ABI0NQQ4-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-5631941", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5631941" } ] }, { "id": "R-BTA-5665868", "name": "AMPK (complex) phosphorylates ULK1 (complex)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SBK8-1", "A0ABI0NQQ4-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-5665868", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5665868" } ] }, { "id": "R-BTA-5672008", "name": "Thr-180 of ULK1 is phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SBK8-1", "A0ABI0NQQ4-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-5672008", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5672008" } ] }, { "id": "R-BTA-5672011", "name": "p-AMPK:AMP binds the ULK complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SBK8-1", "A0ABI0NQQ4-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-5672011", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5672011" } ] }, { "id": "R-BTA-5673768", "name": "p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, lysosomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3SX43-1", "A0AAA9SBK8-1", "A0ABI0NQQ4-1", "A0A3Q1MEZ6-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-5673768", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5673768" } ] }, { "id": "R-BTA-5675868", "name": "ULK1 phosphorylates ATG13 and RB1CC1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SBK8-1", "A0ABI0NQQ4-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-5675868", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5675868" } ] }, { "id": "R-BTA-5679205", "name": "ULK1 phosphorylates Beclin-1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SBK8-1", "A0ABI0NQQ4-1", "F1MTL5-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-5679205", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5679205" } ] }, { "id": "R-BTA-5679239", "name": "ULK complex translocates to the ER", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SBK8-1", "A0ABI0NQQ4-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-5679239", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5679239" } ] }, { "id": "R-BTA-6805470", "name": "AMPK phosphorylates TP53", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NQQ4-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-6805470", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6805470" } ] }, { "id": "R-BTA-9931292", "name": "AMPK phosphorylates CD274", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [ "R-BTA-9931301" ], "enzyme_list": [ "A0ABI0NQQ4-1", "A0AAA9SU81-1" ], "evidence": [ { "id": "R-BTA-9931292", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9931292" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-9931301", "participant_name": "phospho-CD274 [endoplasmic reticulum membrane]", "crossref": [ { "id": "27019", "database": "VGNC", "url": "" }, { "id": "C5NU11", "database": "UniProt", "url": "" }, { "id": "NP_001156884.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJI4", "gene_name": "GSK3A", "activity": [ { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJI4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A3Q1LJI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJI4" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NDU7", "gene_name": "GSK3B", "activity": [ { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NDU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NDU7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A3Q1NDU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NDU7" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SBK8", "gene_name": "ULK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SBK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBK8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SBK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBK8" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MTL5", "gene_name": "PIK3C3", "activity": [ { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "F1MTL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTL5" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "F1MTL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTL5" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "O62829", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SX43", "gene_name": "RRAGA", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q3SX43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX43" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": 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migration, neurite outgrowth and vesicular transport.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LV94", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV94#function" }, { "database": "UniProtKB", "id": "ARBA00058091", "url": "https://www.uniprot.org/uniprotkb/ARBA00058091#function" }, { "database": "UniProtKB", "id": "A0A3Q1MBW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBW7#function" }, { "database": "UniProtKB", "id": "A0A3Q1MR81", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR81#function" }, { "database": "UniProtKB", "id": "A0A3Q1MU95", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU95#function" }, { "database": "UniProtKB", "id": "A0ABI0NT79", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT79#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT79", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT79" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MYO1B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT79", "locus": { "chromosome": "2", "start_pos": 79994785, "end_pos": 79795595, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011256", "url": "https://www.ensembl.org/id/ENSBTAG00000011256" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011256", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011256", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01378", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01378", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23767", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "537282", "url": "https://www.ncbi.nlm.nih.gov/gene/537282", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LV94", "url": "https://www.orthodb.org/?gene=A0A3Q1LV94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MBW7", "url": "https://www.orthodb.org/?gene=A0A3Q1MBW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MU95", "url": "https://www.orthodb.org/?gene=A0A3Q1MU95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13140:SF277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13140:SF277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059731670", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059731670", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LV94", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LV94-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MBW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MBW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MR81", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MR81-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MU95", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MU95-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT79", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT79-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKKSCHLVMSGCLQPMDCSTPGFPVLHHFLELLKLTSIEFVTPSSHLILRRPFLLLASIFPASGSFPQETMAKMEVKTSLLDNMIGVGDMVLLEPLSEDTVIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIEYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEGLVCHQVRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARAGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMRKSQIVIAAWFRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCEEAVTTIAAYWHGTQVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKVPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGPYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAIHLKEGCEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1149, "header": "tr|A0ABI0NT79-1|A0ABI0NT79_BOVIN Isoform 1 of Unconventional myosin-Ib OS=Bos taurus OX=9913 GN=MYO1B PE=3 SV=1 CANONICAL=A0ABI0NT79-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LV94-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT79/entry#A0A3Q1LV94-1", "sequence": { "sequence": "MQETMAKMEVKTSLLDNMIGVGDMVLLEPLSEDTVIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIEYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEGLVCHQVRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARAGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMRKSQIVIAAWFRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCEEAVTTIAAYWHGTQARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKVPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGPYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAIHLKEGCEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1111, "header": "tr|A0A3Q1LV94-1|A0ABI0NT79_BOVIN Computationally mapped isoform of Unconventional myosin-Ib OS=Bos taurus OX=9913 GN=MYO1B PE=3 SV=2 CANONICAL=A0ABI0NT79-1" }, "locus": { "chromosome": "2", "start_pos": 79993572, "end_pos": 79814647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073370.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073370.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061301.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061301.2" } ] } }, { "isoform_ac": "A0A3Q1MBW7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT79/entry#A0A3Q1MBW7-1", "sequence": { "sequence": "MAKMEVKTSLLDNMIGVGDMVLLEPLSEDTVIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIEYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEGLVCHQVRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARAGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMRKSQIVIAAWFRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCEEAVTTIAAYWHGTQARRELSRLKAEARNKHAIAVIWAYWLGSKVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKVPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGPYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAIHLKEGCEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1107, "header": "tr|A0A3Q1MBW7-1|A0ABI0NT79_BOVIN Computationally mapped isoform of Unconventional myosin-Ib OS=Bos taurus OX=9913 GN=MYO1B PE=3 SV=2 CANONICAL=A0ABI0NT79-1" }, "locus": { "chromosome": "2", "start_pos": 79993572, "end_pos": 79830832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084166.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084166.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068263.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068263.2" } ] } }, { "isoform_ac": "A0A3Q1MR81-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT79/entry#A0A3Q1MR81-1", "sequence": { "sequence": "MAKMEVKTSLLDNMIGVGDMVLLEPLSEDTVIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIEYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEGLVCHQVRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARAGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMRKSQIVIAAWFRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCEEAVTTIAAYWHGTQARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKVPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGPYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAIHLKEGCEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1107, "header": "tr|A0A3Q1MR81-1|A0ABI0NT79_BOVIN Computationally mapped isoform of Unconventional myosin-Ib OS=Bos taurus OX=9913 GN=MYO1B PE=3 SV=2 CANONICAL=A0ABI0NT79-1" }, "locus": { "chromosome": "2", "start_pos": 79993572, "end_pos": 79830832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072917.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072917.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056873.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056873.3" } ] } }, { "isoform_ac": "A0A3Q1MU95-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT79/entry#A0A3Q1MU95-1", "sequence": { "sequence": "MQETMAKMEVKTSLLDNMIGVGDMVLLEPLSEDTVIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVRNAMQIVGFMDHEAESVLEVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIEYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEGLVCHQVRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARAGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMRKSQIVIAAWFRRYAQQKRYQQIKSSALVIQSYIRGWKARKILRELKHQKRCEEAVTTIAAYWHGTQVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKVPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGPYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAIHLKEGCEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEFLVQFRQDKVCVKFIQGNQKNGSVPTCKRKNNRLLEVAVP", "length": 1082, "header": "tr|A0A3Q1MU95-1|A0ABI0NT79_BOVIN Computationally mapped isoform of Unconventional myosin-Ib OS=Bos taurus OX=9913 GN=MYO1B PE=3 SV=2 CANONICAL=A0ABI0NT79-1" }, "locus": { "chromosome": "2", "start_pos": 79993572, "end_pos": 79814647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076425.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076425.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074102.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074102.2" } ] } }, { "isoform_ac": "A0ABI0NT79-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT79/entry#A0ABI0NT79-1", "sequence": { "sequence": 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"https://www.ebi.ac.uk/interpro/entry/IPR050307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MF09", "url": "https://www.orthodb.org/?gene=A0A3Q1MF09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MUF4", "url": "https://www.orthodb.org/?gene=A0A3Q1MUF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11863", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11863", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04116", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04116", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6807047", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807047", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005216026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005216026", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MF09", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MF09-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUF4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NP42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NP42-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RLK2", "url": "https://www.uniprot.org/uniprotkb/F6RLK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RLK2-1", "url": "https://www.uniprot.org/uniprotkb/F6RLK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLVLSIADYYFFTPYIYPATWPEDNIFRQAITLLIVTNLGAFILYFFFATLSYYFVYDHLLMKHPQFLKNQVSREITHSVQSMPWMSIPTVLLFLLEVRGYSRLYDGIGEFPYGWFQLVASVLSFLFFTDMLIYWIHRGLHHKLVYKRLHKPHHIWKIPTPFASHAFHPLDGFLQSLPYHIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQLLKPFINGSAHHTDHHMLFDYNYGQYFTLWDRIGGSFRNPSSFEGNGPLNYVKKMAEEKHNSHGGNGYKNEKLFNGECTKTE", "length": 299, "header": "tr|A0ABI0NP42-1|A0ABI0NP42_BOVIN Isoform 1 of Sterol-C5-desaturase OS=Bos taurus OX=9913 GN=SC5D PE=4 SV=1 CANONICAL=A0ABI0NP42-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MF09-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42/entry#A0A3Q1MF09-1", "sequence": { "sequence": "MKRLGPSPEMTLKTPSGSNDGICRVVVAADLYFICLRRAKMDLVLSIADYYFFTPYIYPATWPEDNIFRQAITLLIVTNLGAFILYFFFATLSYYFVYDHLLMKHPQFLKNQVSREITHSVQSMPWMSIPTVLLFLLEVRGYSRLYDGIGEFPYGWFQLVASVLSFLFFTDMLIYWIHRGLHHKLVYKRLHKPHHIWKIPTPFASHAFHPLDGFLQSLPYHIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQLLKPFINGSAHHTDHHMLFDYNYGQYFTLWDRIGGSFRNPSSFEGNGPLNYVKKMAEEKHNSHGGNGYKNEKLFNGECTKTE", "length": 339, "header": "tr|A0A3Q1MF09-1|A0ABI0NP42_BOVIN Computationally mapped isoform of Sterol-C5-desaturase OS=Bos taurus OX=9913 GN=SC5D PE=4 SV=2 CANONICAL=A0ABI0NP42-1" }, "locus": { "chromosome": "15", "start_pos": 31886419, "end_pos": 31882103, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072112.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072112.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072762.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072762.2" } ] } }, { "isoform_ac": "A0A3Q1MUF4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42/entry#A0A3Q1MUF4-1", "sequence": { "sequence": "MSLASGWLAAPAARSVRLGYALPDFGCLADRRDPQSGTAWAPEEPSRQLVSGRPILSRAKMDLVLSIADYYFFTPYIYPATWPEDNIFRQAITLLIVTNLGAFILYFFFATLSYYFVYDHLLMKHPQFLKNQVSREITHSVQSMPWMSIPTVLLFLLEVRGYSRLYDGIGEFPYGWFQLVASVLSFLFFTDMLIYWIHRGLHHKLVYKRLHKPHHIWKIPTPFASHAFHPLDGFLQSLPYHIYPFIFPLHKLLKPFINGSAHHTDHHMLFDYNYGQYFTLWDRIGGSFRNPSSFEGNGPLNYVKKMAEEKHNSHGGNGYKNEKLFNGECTKTE", "length": 333, "header": "tr|A0A3Q1MUF4-1|A0ABI0NP42_BOVIN Computationally mapped isoform of Sterol-C5-desaturase OS=Bos taurus OX=9913 GN=SC5D PE=4 SV=2 CANONICAL=A0ABI0NP42-1" }, "locus": { "chromosome": "15", "start_pos": 31886419, "end_pos": 31876074, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084448.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084448.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058490.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058490.2" } ] } }, { "isoform_ac": "A0ABI0NP42-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42/entry#A0ABI0NP42-1", "sequence": { "sequence": "MDLVLSIADYYFFTPYIYPATWPEDNIFRQAITLLIVTNLGAFILYFFFATLSYYFVYDHLLMKHPQFLKNQVSREITHSVQSMPWMSIPTVLLFLLEVRGYSRLYDGIGEFPYGWFQLVASVLSFLFFTDMLIYWIHRGLHHKLVYKRLHKPHHIWKIPTPFASHAFHPLDGFLQSLPYHIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQLLKPFINGSAHHTDHHMLFDYNYGQYFTLWDRIGGSFRNPSSFEGNGPLNYVKKMAEEKHNSHGGNGYKNEKLFNGECTKTE", "length": 299, "header": "tr|A0ABI0NP42-1|A0ABI0NP42_BOVIN Isoform 1 of Sterol-C5-desaturase OS=Bos taurus OX=9913 GN=SC5D PE=4 SV=1 CANONICAL=A0ABI0NP42-1" }, "locus": { "chromosome": "15", "start_pos": 31886419, "end_pos": 31882315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140334.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140334.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107606.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107606.1" } ] } }, { "isoform_ac": "F6RLK2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42/entry#F6RLK2-1", "sequence": { "sequence": "MSLASGWLAAPAARSVRLGYALPDFGCLADRRDPQSGTAWAPEEPSRQLVSGRPILSRAKMDLVLSIADYYFFTPYIYPATWPEDNIFRQAITLLIVTNLGAFILYFFFATLSYYFVYDHLLMKHPQFLKNQVSREITHSVQSMPWMSIPTVLLFLLEVRGYSRLYDGIGEFPYGWFQLVASVLSFLFFTDMLIYWIHRGLHHKLVYKRLHKPHHIWKIPTPFASHAFHPLDGFLQSLPYHIYPFIFPLHKVVYLSLYILVNIWTISIHDGDFRVPQLLKPFINGSAHHTDHHMLFDYNYGQYFTLWDRIGGSFRNPSSFEGNGPLNYVKKMAEEKHNSHGGNGYKNEKLFNGECTKTE", "length": 359, "header": "tr|F6RLK2-1|A0ABI0NP42_BOVIN Computationally mapped isoform of Sterol-C5-desaturase OS=Bos taurus OX=9913 GN=SC5D PE=4 SV=2 CANONICAL=A0ABI0NP42-1" }, "locus": { "chromosome": "15", "start_pos": 31886419, "end_pos": 31876074, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047079.5", "url": "https://www.ensembl.org/id/ENSBTAT00000047079.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044313.4", "url": "https://www.ensembl.org/id/ENSBTAP00000044313.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6807047", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807047", "resource": "Reactome", "description": "Cholesterol biosynthesis via desmosterol (Bloch pathway)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "C-5 sterol desaturase activity", "id": "GO:0000248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000248", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42" } ], "pmid": "" }, { "name": "delta7-sterol 5(6)-desaturase activity", "id": "GO:0050046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050046", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cholesterol biosynthetic process via lathosterol", "id": "GO:0033490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033490", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42" } ], "pmid": "" }, { "name": "lipid biosynthetic process", "id": "GO:0008610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008610", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process via desmosterol", "id": "GO:0033489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033489", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42" } ], "pmid": "" }, { "name": "negative regulation of ferroptosis", "id": "GO:0110076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110076", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NP42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NP42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP42" }, { "id": "PF04116", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04116" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fatty acid hydroxylase", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 252, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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"categories": [ "Gene Expression" ] }, { "id": "524593", "url": "https://www.ncbi.nlm.nih.gov/gene/524593", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NN05", "url": "https://www.orthodb.org/?gene=A0A3Q1NN05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N308", "url": "https://www.orthodb.org/?gene=F1N308", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31131:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31131:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13840", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13840", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18700", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18700", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9639288", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9639288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002698225", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698225", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1NN05", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NN05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NN05-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NN05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NR50", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NR50-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N308", "url": "https://www.uniprot.org/uniprotkb/F1N308", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N308-1", "url": "https://www.uniprot.org/uniprotkb/F1N308-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELHILEHRLQVASVAKESIPLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGSFSSSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRERDLPFVTHTLSSEFTILRVVNGETVAAENLGITNGFVKPKMVQRPVIHPLSSPSNRFCVTSLDPDTLPTVATLLMDVMFYSNGVKDPLVSGDDCDHIRFFSFSLIEGYISLVMDVQTQQRFPSNLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYISTFKFDHALVPEENINGVISALKVSQAEKH", "length": 329, "header": "tr|A0ABI0NR50-1|A0ABI0NR50_BOVIN Isoform 1 of Cytosolic arginine sensor for mTORC1 subunit 2 OS=Bos taurus OX=9913 GN=CASTOR2 PE=3 SV=1 CANONICAL=A0ABI0NR50-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NN05-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR50/entry#A0A3Q1NN05-1", "sequence": { "sequence": "MELHILEHRLQVASVAKESIPLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGSFSSSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRERDLPFVTHTLSSEFTILRVVNGETVAAENLGITNGFVKPKMVQRPVIHPLSSPSNRFCVTSLDPDTLPTVATLLMDVMFYSNGVKDPLVSGDDCDHIRFFSFSLIEGYISLVMDVQTQQRFPSNLLFTSASGELWKMVRIGGQPLGFGPPTLLLQMASFHFFCETEQYSVAYSDVFRSIPMYHIFFIHSSVSGHFGCFYVLAAMNMGTHVSFQIRVLSTYMSQSGIAGSRDNSAFSFLRNLHICFPQ", "length": 376, "header": "tr|A0A3Q1NN05-1|A0ABI0NR50_BOVIN Computationally mapped isoform of Cytosolic arginine sensor for mTORC1 subunit 2 OS=Bos taurus OX=9913 GN=CASTOR2 PE=3 SV=2 CANONICAL=A0ABI0NR50-1" }, "locus": { "chromosome": "25", "start_pos": 32657523, "end_pos": 32610767, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080805.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080805.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074057.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074057.2" } ] } }, { "isoform_ac": "A0ABI0NR50-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR50/entry#A0ABI0NR50-1", "sequence": { "sequence": "MELHILEHRLQVASVAKESIPLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGSFSSSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRERDLPFVTHTLSSEFTILRVVNGETVAAENLGITNGFVKPKMVQRPVIHPLSSPSNRFCVTSLDPDTLPTVATLLMDVMFYSNGVKDPLVSGDDCDHIRFFSFSLIEGYISLVMDVQTQQRFPSNLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYISTFKFDHALVPEENINGVISALKVSQAEKH", "length": 329, "header": "tr|A0ABI0NR50-1|A0ABI0NR50_BOVIN Isoform 1 of Cytosolic arginine sensor for mTORC1 subunit 2 OS=Bos taurus OX=9913 GN=CASTOR2 PE=3 SV=1 CANONICAL=A0ABI0NR50-1" }, "locus": { "chromosome": "25", "start_pos": 32659476, "end_pos": 32610767, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137344.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137344.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104886.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104886.1" } ] } }, { "isoform_ac": "F1N308-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR50/entry#F1N308-1", "sequence": { "sequence": "MELHILEHRLQVASVAKESIPLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGSFSSSQPIGVTKIAKSVIAPLADQNISVFMLSTYQTDFILVRERDLPFVTHTLSSEFTILRVVNGETVAAENLGITNGFVKPKMVQRPVIHPLSSPSNRFCVTSLDPDTLPTVATLLMDVMFYSNGVKDPLVSGDDCDHIRFFSFSLIEGYISLVMDVQTQQRFPSNLLFTSASGELWKMVRIGGQPLGFVYRLPDAVASLAAEHRLKASE", "length": 297, "header": "tr|F1N308-1|A0ABI0NR50_BOVIN Computationally mapped isoform of Cytosolic arginine sensor for mTORC1 subunit 2 OS=Bos taurus OX=9913 GN=CASTOR2 PE=3 SV=4 CANONICAL=A0ABI0NR50-1" }, "locus": { "chromosome": "25", "start_pos": 32658671, "end_pos": 32610767, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019176.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019176.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019176.7", "url": "https://www.ensembl.org/id/ENSBTAP00000019176.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-9639288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9639288", "resource": "Reactome", "description": "Amino acids regulate mTORC1" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NR50", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR50" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NR50", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR50" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NR50", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR50" } ], "pmid": "" }, { "name": "cellular response to L-arginine", "id": "GO:1903577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903577", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NR50", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR50" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NR50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR50" }, { "id": "PF13840", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13840" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CASTOR ACT", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 140, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NR50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR50" }, { "id": "PF18700", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18700" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CASTOR1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 69, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NR50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR50" }, { "id": "PF21389", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21389" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytosolic arginine sensor for mTORC1 subunit 1/2 ACT-like", "eco_id": "ECO_0000259", "start_pos": 177, "end_pos": 259, "start_aa": "His", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NSU1-1", "uniprot_ac": "A0ABI0NSU1", "uniprot_id": "A0ABI0NSU1_BOVIN", "mass": { "chemical_mass": 46705.0, "monoisotopic_mass": 46705.0 }, "refseq": {}, "gene_names": [ { "name": "ZSCAN31", "type": "recommended", "evidence": [ { "id": "A0ABI0NSU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1" } ] } ], "protein_names": [ { "name": "Zinc finger and SCAN domain containing 31", "type": "synonym", "evidence": [ { "id": "A0ABI0NSU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSU1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZSCAN31", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1", "locus": { "chromosome": "23", "start_pos": 30379817, "end_pos": 30371117, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000037988", "url": "https://www.ensembl.org/id/ENSBTAG00000037988" } ] } } ], "crossref": [ { "id": "ENSBTAG00000037988", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000037988", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KQRGHPT", "url": "https://omabrowser.org/oma/group/KQRGHPT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR14196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14196:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14196:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3S5ZPQ0", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3S5ZPQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSU1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSU1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASAGEQDGLKIVKVEEDPIWDQEPYLRENNFSGQEASRQLFRHFCYQETPGPREALSRLRELCHQWLRPDTHTKEQILELLVLEQFLTILPEELQAWVCEHHPESGEEAVAAVEDLERELSEPENQAPDCEHGLAEMLSGDAVHLKAKEESTAFQLQSMVMQLKCESFGVHKFGEQDGETVLKNQDLTSKEVLKEMGHFEDSRLQRDIPLDSKYRETCKHESREEKQSGQPTGERCHKCNECGKSFTQSSVLIQHQRIHTGEKPYECEECGKTFSQRSGLIEHQRSHTGEKPYQCKDCGKAFSASNSLIRHRRIHTGEKPYECEECGKTFRLSSYLVQHQRIHTGEKRYHCNECGKAFSQNAGLFQHLRIHTGEKPYQCGQCSKSFSRRTLLIKHQRSHTGERP", "length": 405, "header": "tr|A0ABI0NSU1-1|A0ABI0NSU1_BOVIN Isoform 1 of Zinc finger and SCAN domain containing 31 OS=Bos taurus OX=9913 GN=ZSCAN31 PE=3 SV=1 CANONICAL=A0ABI0NSU1-1" }, "isoforms": [ { "isoform_ac": "A0A3S5ZPQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1/entry#A0A3S5ZPQ0-1", "sequence": { "sequence": "MASAGEQDGLKIVKVEEDPIWDQEPYLRENNFSGQEASRQLFRHFCYQETPGPREALSRLRELCHQWLRPDTHTKEQILELLVLEQFLTILPEELQAWVCEHHPESGEEAVAAVEDLERELSEPENQAPDCEHGLAEMLSGDAVHLKAKEESTAFQLQSMVMQLKCESFGVHKFGEQDGETVLKNQDLTSKEVLKEMGHFEDSRLQRDIPLDSKYRETCKHESREEKQSGQPTGERCHKCNECGKSFTQSSVLIQHQRIHTGEKPYECEECGKTFSQRSGLIEHQRSHTGEKPYQCKDCGKAFSASNSLIRHRRIHTGEKPYECEECGKTFRLSSYLVQHQRIHTGEKRYHCNECGKAFSQNAGLFQHLRIHTGEKPYQCGQCSKSFSRRTLLIKHQRSHTGERPYECDECGKAFSHHCNLIRHFRIHTVVKLD", "length": 434, "header": "tr|A0A3S5ZPQ0-1|A0ABI0NSU1_BOVIN Computationally mapped isoform of Zinc finger and SCAN domain containing 31 OS=Bos taurus OX=9913 GN=ZSCAN31 PE=3 SV=2 CANONICAL=A0ABI0NSU1-1" }, "locus": { "chromosome": "23", "start_pos": 30379814, "end_pos": 30377190, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000057234.5", "url": "https://www.ensembl.org/id/ENSBTAT00000057234.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052313.4", "url": "https://www.ensembl.org/id/ENSBTAP00000052313.4" } ] } }, { "isoform_ac": "A0ABI0NSU1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1/entry#A0ABI0NSU1-1", "sequence": { "sequence": "MASAGEQDGLKIVKVEEDPIWDQEPYLRENNFSGQEASRQLFRHFCYQETPGPREALSRLRELCHQWLRPDTHTKEQILELLVLEQFLTILPEELQAWVCEHHPESGEEAVAAVEDLERELSEPENQAPDCEHGLAEMLSGDAVHLKAKEESTAFQLQSMVMQLKCESFGVHKFGEQDGETVLKNQDLTSKEVLKEMGHFEDSRLQRDIPLDSKYRETCKHESREEKQSGQPTGERCHKCNECGKSFTQSSVLIQHQRIHTGEKPYECEECGKTFSQRSGLIEHQRSHTGEKPYQCKDCGKAFSASNSLIRHRRIHTGEKPYECEECGKTFRLSSYLVQHQRIHTGEKRYHCNECGKAFSQNAGLFQHLRIHTGEKPYQCGQCSKSFSRRTLLIKHQRSHTGERP", "length": 405, "header": "tr|A0ABI0NSU1-1|A0ABI0NSU1_BOVIN Isoform 1 of Zinc finger and SCAN domain containing 31 OS=Bos taurus OX=9913 GN=ZSCAN31 PE=3 SV=1 CANONICAL=A0ABI0NSU1-1" }, "locus": { "chromosome": "23", "start_pos": 30379729, "end_pos": 30377190, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138758.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138758.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106118.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106118.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "I3LQQ7-1", "protein_name": "Zinc finger and SCAN domain containing 31", "gene_name": "ZSCAN31", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASTGEQDGLKIVKVEEDPVWNQETYLQESSFSGQEASRQLFRHFCYQETPGPREALSRLRELCHQWLRPDTHTKEQILELLVLEQFLTILPEELQAWVREHHPESGEEAVAAVEDLERELSEPENQAPDCEHGHSEVLSGDAVHLKAKQESAATQLQSMVTQLKYESFGPQKLGEQDGETILENKDLVSKQEVLKEMGHFENSRLQRDVPLDSKYREACKRENRVENQRGHPSGERRHRCNECGKSFTQSSVLIQHQRTHTGEKPYECEECGKTFSQRSGLIEHQRSHTGEKPYQCKECGKAFSASNGLIRHRRIHTGEKPYECEECGKAFRLSSYLVQHQRIHTGEKRYRCNECGKAFSQNAGLFQHLRIHTGEKPYQCSQCSKSFSRRTLLIKHQRSHTGERPYECDECGKAFSHHCNLIRHFRIHTVGSSRHGSVVNESD", "length": 444 }, "evidence": [ { "id": "A0ABI0NSU1", "url": "https://omabrowser.org/oma/group/A0ABI0NSU1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q96LW9-1", "protein_name": "Zinc finger and SCAN domain-containing protein 31", "gene_name": "ZSCAN31", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASTEEQYDLKIVKVEEDPIWDQETHLRGNNFSGQEASRQLFRQFCYQETPGPREALSRLRELCHQWLRPEIHTKEQILELLVLEQFLTILPEELQAWVREHHPESGEEAVAVVEDLEQELSEPGNQAPDHEHGHSEVLLEDVEHLKVKQEPTDIQLQPMVTQLRYESFCLHQFQEQDGESIPENQELASKQEILKEMEHLGDSKLQRDVSLDSKYRETCKRDSKAEKQQAHSTGERRHRCNECGKSFTKSSVLIEHQRIHTGEKPYECEECGKAFSRRSSLNEHRRSHTGEKPYQCKECGKAFSASNGLTRHRRIHTGEKPYECKVCGKAFLLSSCLVQHQRIHTGEKRYQCRECGKAFIQNAGLFQHLRVHTGEKPYQCSQCSKLFSKRTLLKKHQKIHTGERP", "length": 406 }, "evidence": [ { "id": "A0ABI0NSU1", "url": "https://omabrowser.org/oma/group/A0ABI0NSU1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSU1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSU1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSU1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSU1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSU1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NSU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 238, "end_pos": 265, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NSU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSU1" }, { "id": "PS50804", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50804" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCAN box", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 121, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 31, "end_pos": 33 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NTD4-1", "uniprot_ac": "A0ABI0NTD4", "uniprot_id": "A0ABI0NTD4_BOVIN", "mass": { "chemical_mass": 114534.0, "monoisotopic_mass": 114534.0 }, "refseq": { "ac": "XP_005215131", "name": "teashirt homolog 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215131" }, "gene_names": [ { "name": "TSHZ2", "type": "recommended", "evidence": [ { "id": "A0ABI0NTD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4" } ] }, { "name": "TSHZ2", "type": "synonym", "evidence": [ { "id": "XP_005215131", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215131" } ] } ], "protein_names": [ { "name": "Teashirt zinc finger homeobox 2", "type": "synonym", "evidence": [ { "id": "A0ABI0NTD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4/entry#names_and_taxonomy" } ] }, { "name": "teashirt homolog 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_005215131", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215131" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TSHZ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4", "locus": { "chromosome": "13", "start_pos": 81067806, "end_pos": 80581116, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007917", "url": "https://www.ensembl.org/id/ENSBTAG00000007917" } ] } } ], "crossref": [ { "id": "ENSBTAG00000007917", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007917", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "515677", "url": "https://www.ncbi.nlm.nih.gov/gene/515677", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N1F0", "url": "https://www.orthodb.org/?gene=F1N1F0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12487", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12487", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12487:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12487:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF26094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005215131", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215131", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RV69", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RV69-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZU9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZU9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTD4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N1F0", "url": "https://www.uniprot.org/uniprotkb/F1N1F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N1F0-1", "url": "https://www.uniprot.org/uniprotkb/F1N1F0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRRKQQAPKRAAGYAQEEQLKEEEEIKEEEEEEEDSGSGAQPQGSNDAGTDEELETGPEQKGCFSYQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCGRDASDKKASVHPKLPNEAHSCMDKMTAVYANILSDSYWSGLGLGFKLSNSERRNCDTRNGGNKTDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSFADSFPPQKNANLQLSCNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSDAPNSDALAPKPSSNSASDAAASSTELKKDSKKEKPEEINKDEKVMKSEDYEDPLQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPSLPMGSQVLQIRPNLSNKLRPIAPKWKVMPLVSVPAHLAPYTQVKKELTDKEEAVRECGKESPCEEASSFSHSEGHAFCKSEPPAESKKVEPRPPKEEDKLMREGSEKEKAPALEPASPLSNGCAIANPAAALPGINPLSALQSVLNNHLGKATEPLRTPSCSSPSSSTMSMFHKPSLSVMDKPVLSPPSTRPASVSRRYLFENNDQPIDLTKSKSKKAESSQAQSCTSPPQKHALSDIADMVKVLPKATTPKPATSPRVPPVKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRLAVEQQGKAEQEISRVSSAQRSPESTAGEEDTDSKFKCKLCCRTFVSKHAVKLHLSKTHSKSPEHHSQFVTDADEE", "length": 1035, "header": "tr|A0ABI0NTD4-1|A0ABI0NTD4_BOVIN Isoform 1 of Teashirt zinc finger homeobox 2 OS=Bos taurus OX=9913 GN=TSHZ2 PE=3 SV=1 CANONICAL=A0ABI0NTD4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RV69-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4/entry#A0AAA9RV69-1", "sequence": { "sequence": "MNNRQNRGVSSTASGVRAVERGYAQEEQLKEEEEIKEEEEEEEDSGSGAQPQGSNDAGTDEELETGPEQKGCFSYQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCGRDASDKKASVHPKLPNEAHSCMDKMTAVYANILSDSYWSGLGLGFKLSNSERRNCDTRNGGNKTDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSFADSFPPQKNANLQLSCNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSDAPNSDALAPKPSSNSASDAAASSTELKKDSKKEKPEEINKDEKVMKSEDYEDPLQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPSLPMGSQVLQIRPNLSNKLRPIAPKWKVMPLVSVPAHLAPYTQVKKELTDKEEAVRECGKESPCEEASSFSHSEGHAFCKSEPPAESKKVEPRPPKEEDKLMREGSEKEKAPALEPASPLSNGCAIANPAAALPGINPLSALQSVLNNHLGKATEPLRTPSCSSPSSSTMSMFHKPSLSVMDKPVLSPPSTRPASVSRRYLFENNDQPIDLTKSKSKKAESSQAQSCTSPPQKHALSDIADMVKVLPKATTPKPATSPRVPPVKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRLAVEQQGKAEQEISRVSSAQRSPESTAGEEDTDSKFKCKLCCRTFVSKHAVKLHLSKTHSKSPEHHSQFVTDADEE", "length": 1043, "header": "tr|A0AAA9RV69-1|A0ABI0NTD4_BOVIN Computationally mapped isoform of Teashirt zinc finger homeobox 2 OS=Bos taurus OX=9913 GN=TSHZ2 PE=3 SV=1 CANONICAL=A0ABI0NTD4-1" }, "locus": { "chromosome": "13", "start_pos": 80869574, "end_pos": 80842480, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114655.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114655.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076150.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076150.1" } ] } }, { "isoform_ac": "A0AAA9TZU9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4/entry#A0AAA9TZU9-1", "sequence": { "sequence": "MPRRKQQAPKRAAGYAQEEQLKEEEEIKEEEEEEEDSGSGAQPQGSNDAGTDEELETGPEQKGCFSYQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCGRDASDKKASVHPKLPNEAHSCMDKMTAVYANILSDSYWSGLGLGFKLSNSERRNCDTRNGGNKTDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSFADSFPPQKNANLQLSCNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSDAPNSDALAPKPSSNSASDAAASSTELKKDSKKEKPEEINKDEKVMKSEDYEDPLQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPSLPMGSQVLQIRPNLSNKLRPIAPKWKVMPLVSVPAHLAPYTQVKKELTDKEEAVRECGKESPCEEASSFSHSEGHAFCKSEPPAESKKVEPRPPKEEDKLMREGSEKEKAPALEPASPLSNGCAIANPAAALPGINPLSALQSVLNNHLGKATEPLRTPSCSSPSSSTMSMFHKPSLSVMDKPVLSPPSTRPASVSRRYLFENNDQPIDLTKSKSKKAESSQAQSCTSPPQKHALSDIADMVKVLPKATTPKPATSPRVPPVKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRLAVEQQGKAEQEISRVSSAQRSPESTAGEEDTDSKFK", "length": 996, "header": "tr|A0AAA9TZU9-1|A0ABI0NTD4_BOVIN Computationally mapped isoform of Teashirt zinc finger homeobox 2 OS=Bos taurus OX=9913 GN=TSHZ2 PE=3 SV=1 CANONICAL=A0ABI0NTD4-1" }, "locus": { "chromosome": "13", "start_pos": 80869458, "end_pos": 80581315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093214.2", "url": "https://www.ensembl.org/id/ENSBTAT00000093214.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103112.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103112.1" } ] } }, { "isoform_ac": "A0ABI0NTD4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4/entry#A0ABI0NTD4-1", "sequence": { "sequence": "MPRRKQQAPKRAAGYAQEEQLKEEEEIKEEEEEEEDSGSGAQPQGSNDAGTDEELETGPEQKGCFSYQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCGRDASDKKASVHPKLPNEAHSCMDKMTAVYANILSDSYWSGLGLGFKLSNSERRNCDTRNGGNKTDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSFADSFPPQKNANLQLSCNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSDAPNSDALAPKPSSNSASDAAASSTELKKDSKKEKPEEINKDEKVMKSEDYEDPLQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPSLPMGSQVLQIRPNLSNKLRPIAPKWKVMPLVSVPAHLAPYTQVKKELTDKEEAVRECGKESPCEEASSFSHSEGHAFCKSEPPAESKKVEPRPPKEEDKLMREGSEKEKAPALEPASPLSNGCAIANPAAALPGINPLSALQSVLNNHLGKATEPLRTPSCSSPSSSTMSMFHKPSLSVMDKPVLSPPSTRPASVSRRYLFENNDQPIDLTKSKSKKAESSQAQSCTSPPQKHALSDIADMVKVLPKATTPKPATSPRVPPVKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRLAVEQQGKAEQEISRVSSAQRSPESTAGEEDTDSKFKCKLCCRTFVSKHAVKLHLSKTHSKSPEHHSQFVTDADEE", "length": 1035, "header": "tr|A0ABI0NTD4-1|A0ABI0NTD4_BOVIN Isoform 1 of Teashirt zinc finger homeobox 2 OS=Bos taurus OX=9913 GN=TSHZ2 PE=3 SV=1 CANONICAL=A0ABI0NTD4-1" }, "locus": { "chromosome": "13", "start_pos": 80869574, "end_pos": 80581315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148621.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148621.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107709.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107709.1" } ] } }, { "isoform_ac": "F1N1F0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4/entry#F1N1F0-1", "sequence": { "sequence": "MPRRKQQAPKRAAGYAQEEQLKEEEEIKEEEEEEEDSGSGAQPQGSNDAGTDEELETGPEQKGCFSYQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCGRDASDKKASVHPKLPNEAHSCMDKMTAVYANILSDSYWSGLGLGFKLSNSERRNCDTRNGGNKTDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSFADSFPPQKNANLQLSCNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSDAPNSDALAPKPSSNSASDAAASSTELKKDSKKEKPEEINKDEKVMKSEDYEDPLQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPSLPMGSQVLQIRPNLSNKLRPIAPKWKVMPLVSVPAHLAPYTQVKKELTDKEEAVRECGKESPCEEASSFSHSEGHAFCKSEPPAESKKVEPRPPKEEDKLMREGSEKEKAPALEPASPLSNGCAIANPAAALPGINPLSALQSVLNNHLGKATEPLRTPSCSSPSSSTMSMFHKPSLSVMDKPVLSPPSTRPASVSRRYLFENNDQPIDLTKSKSKKAESSQAQSCTSPPQKHALSDIADMVKVLPKATTPKPATSPRVPPVKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRLAVEQQGKAEQEISRVSSAQRSPESTAGEEDTDSKFKCLRKDPGKG", "length": 1005, "header": "tr|F1N1F0-1|A0ABI0NTD4_BOVIN Computationally mapped isoform of Teashirt zinc finger homeobox 2 OS=Bos taurus OX=9913 GN=TSHZ2 PE=3 SV=4 CANONICAL=A0ABI0NTD4-1" }, "locus": { "chromosome": "13", "start_pos": 80903794, "end_pos": 80581315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000033918.6", "url": "https://www.ensembl.org/id/ENSBTAT00000033918.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000033821.6", "url": "https://www.ensembl.org/id/ENSBTAP00000033821.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NTD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTD4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 276, "end_pos": 305, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 236, "end_pos": 238 }, { "start_pos": 571, "end_pos": 573 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NSG8-1", "uniprot_ac": "A0ABI0NSG8", "uniprot_id": "A0ABI0NSG8_BOVIN", "mass": { "chemical_mass": 71463.0, "monoisotopic_mass": 71463.0 }, "refseq": { "ac": "NP_001192702", "name": "kelch-like protein 22", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192702" }, "gene_names": [ { "name": "KLHL22", "type": "recommended", "evidence": [ { "id": "A0ABI0NSG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ] }, { "name": "KLHL22", "type": "synonym", "evidence": [ { "id": "NP_001192702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192702" } ] } ], "protein_names": [ { "name": "Kelch-like protein 22", "type": "recommended", "evidence": [ { "id": "A0ABI0NSG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8/entry#names_and_taxonomy" } ] }, { "name": "kelch-like 22", "type": "synonym", "evidence": [ { "id": "NP_001192702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192702" } ] }, { "name": "kelch-like protein 22", "type": "synonym", "evidence": [ { "id": "NP_001192702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192702" } ] } ], "function": [ { "annotation": "Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation. The BCR(KLHL22) ubiquitin ligase complex is also responsible for the amino acid-stimulated 'Lys-48' polyubiquitination and proteasomal degradation of DEPDC5. Through the degradation of DEPDC5, releases the GATOR1 complex-mediated inhibition of the TORC1 pathway. It is therefore an amino acid-dependent activator within the amino acid-sensing branch of the TORC1 pathway, indirectly regulating different cellular processes including cell growth and autophagy.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8#function" }, { "database": "UniProtKB", "id": "ARBA00060035", "url": "https://www.uniprot.org/uniprotkb/ARBA00060035#function" }, { "database": "UniProtKB", "id": "A0A3Q1MPJ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPJ6#function" }, { "database": "UniProtKB", "id": "F1N1V7", "url": "https://www.uniprot.org/uniprotkb/F1N1V7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KLHL22", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8", "locus": { "chromosome": "17", "start_pos": 72505905, "end_pos": 72484120, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020161", "url": "https://www.ensembl.org/id/ENSBTAG00000020161" } ] } } ], "crossref": [ { "id": "ENSBTAG00000020161", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020161", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18461", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18461", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540134", "url": "https://www.ncbi.nlm.nih.gov/gene/540134", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540134", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540134", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MPJ6", "url": "https://www.orthodb.org/?gene=A0A3Q1MPJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N1V7", "url": "https://www.orthodb.org/?gene=F1N1V7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192702", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192702", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPJ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXH3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXH3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THR2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THR2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSG8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N1V7", "url": "https://www.uniprot.org/uniprotkb/F1N1V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N1V7-1", "url": "https://www.uniprot.org/uniprotkb/F1N1V7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEEQEFARLCKLPTQPSHPHCVSSTYRSAQHSQALLRGLLALRDSGILFDVVLVVEGKQLEAHRILLAASCDYFRGMFAGGLKEMEQEEVLIHGVSYNAMCQILHFIYTSELELSLSNVQETLVAACQLQIPEIIHFCCDFLTPWVDEDNILDVYRLAELFDLSRLTEQLDAYILKNFVAFSRTDKYRQLPLEKVYALLSSNRLEVSCETEVYEGALLYHYPPEQVQADRLPLHEPPKLLETVRFPLMEAEVLQRLHDKLEPSPLRDTVAEALMYHRNESLQPSLQGPQTELRSDFQCVVGFGGIHSTPSTVLSDQAKYLNPLLGEWKHFTASLAPRMSNQGIAVLNNFVYLIGGDNNVQGFRAESRCWRYDPRHNRWFQIQPLQQEHADLCVCVVGGYIYAVAGRDYHNDLTAVERYDPATNSWAYVAPLKREVYAHAGAALDGKMYVTCGRRGEDYLKETHCYEPGSDTWHTLADGPVRRAWHGMATLLDKLYVIGGSNNDAGYRRDVHQVACYSCRSGQWSSVCPLPAGHGEPGIAVLDSRIYVLGGRSHNRGSRTGYVHIYDAGRDRWEEGPQLDNSISGLAACVLTLPRSLLLEPPRGTPDRSQADPDFASEVMSVSDWEEFDNSSED", "length": 634, "header": "tr|A0ABI0NSG8-1|A0ABI0NSG8_BOVIN Isoform 1 of Kelch-like protein 22 OS=Bos taurus OX=9913 GN=KLHL22 PE=4 SV=1 CANONICAL=A0ABI0NSG8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MPJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8/entry#A0A3Q1MPJ6-1", "sequence": { "sequence": "MEERELTAAELRLGAVVRMAEEQEFARLCKLPTQPSHPHCVSSTYRSAQHSQALLRGLLALRDSGILFDVVLVVEGKQLEAHRILLAASCDYFRGMFAGGLKEMEQEEVLIHGVSYNAMCQILHFIYTSELELSLSNVQETLVAACQLQIPEIIHFCCDFLTPWVDEDNILDVYRLAELFDLSRLTEQLDAYILKNFVAFSRTDKYRQLPLEKVYALLSSNRLEVSCETEVYEGALLYHYPPEQVQADRLPLHEPPKLLETVRFPLMEAEVLQRLHDKLEPSPLRDTVAEALMYHRNESLQPSLQGPQTELRSDFQCVVGFGGIHSTPSTVLSDQAKYLNPLLGEWKHFTASLAPRMSNQGIAVLNNFVYLIGGDNNVQGFRAESRCWRYDPRHNRWFQIQPLQQEHADLCVCVVGGYIYAVAGRDYHNDLTAVERYDPATNSWAYVAPLKREVYAHAGAALDGKMYVTCGRRGEDYLKETHCYEPGSDTWHTLADGPVRRAWHGMATLLDKLYVIGGSNNDAGYRRDVHQVACYSCRSGQWSSVCPLPAGHGEPGIAVLDSRIYVLGGRSHNRGSRTGYVHIYDAGRDRWEEGPQLDNSISGLAACVLTLPRSLLLEPPRGTPDRSQADPDFASEVMSVSDWEEFDNSSED", "length": 652, "header": "tr|A0A3Q1MPJ6-1|A0ABI0NSG8_BOVIN Computationally mapped isoform of Kelch-like protein 22 OS=Bos taurus OX=9913 GN=KLHL22 PE=4 SV=2 CANONICAL=A0ABI0NSG8-1" }, "locus": { "chromosome": "17", "start_pos": 72505325, "end_pos": 72491001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085830.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085830.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073854.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073854.2" } ] } }, { "isoform_ac": "A0AAA9RXH3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8/entry#A0AAA9RXH3-1", "sequence": { "sequence": "MEERELTAAELRLGAVVRMAEEQEFARLCKLPTQPSHPHCVSSTYRSAQHSQALLRGLLALRDSGILFDVVLVVEGKQLEAHRILLAASCDYFRGMFAGGLKEMEQEEVLIHGVSYNAMCQILHFIYTSELELSLSNVQETLVAACQLQIPEIIHFCCDFLTPWVDEDNILDVYRLAELFDLSRLTEQLDAYILKNFVAFSRTDKYRQLPLEKVYALLSSNRLEVSCETEVYEGALLYHYPPEQVQADRLPLHEPPKLLETVRFPLMEAEVLQRLHDKLEPSPLRDTVAEALMYHRNESLQPSLQGPQTELRSDFQCVVGFGGIHSTPSTVLSDQAKYLNPLLGEWKHFTASLAPRMSNQGIAVLNNFVYLIGGDNNVQGFRAESRCWRYDPRHNRWFQIQPLQQEHADLCVCVVGGYIYAVAGRDYHNDLTAVERYDPATNSWAYVAPLKREVYAHAGAALDGKMYVTCGRRGEDYLKETHCYEPGSDTWHTLADGPVRRAWHGMATLLDKLYVIGGSNNDAGYRRDVHQLGGPPQTQRRKPAGACADSPGVFPRQSPGRVSVLSPGVSAELSPCGRARWPATAADPGSGPPSAHSRPGMGSRASLCSTAGSTCWAAAHTTAAAARAMCTSTTQAGTAGRRGRSWTTPSQAWLPACSPCRGPCCSSPPGGPLTAARPTQTSRPR", "length": 685, "header": "tr|A0AAA9RXH3-1|A0ABI0NSG8_BOVIN Computationally mapped isoform of Kelch-like protein 22 OS=Bos taurus OX=9913 GN=KLHL22 PE=4 SV=1 CANONICAL=A0ABI0NSG8-1" }, "locus": { "chromosome": "17", "start_pos": 72505278, "end_pos": 72491001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129150.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129150.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078208.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078208.1" } ] } }, { "isoform_ac": "A0AAA9THR2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8/entry#A0AAA9THR2-1", "sequence": { "sequence": "MAEEQEFARLCKLPTQPSHPHCVSSTYRSAQHSQALLRGLLALRDSGILFDVVLVVEGKQLEAHRILLAASCDYFRGMFAGGLKEMEQEEVLIHGVSYNAMCQILHFIYTSELELSLSNVQETLVAACQLQIPEIIHFCCDFLTPWVDEDNILDVYRLAELFDLSRLTEQLDAYILKNFVAFSRTDKYRQLPLEKVYALLSSNRLEVSCETEVYEGALLYHYPPEQVQADRLPLHEPPKLLETVRFPLMEAEVLQRLHDKLEPSPLRDTVAEALMYHRNESLQPSLQGPQTELRSDFQCVVGFGGIHSTPSTVLSDQAKYLNPLLGEWKHFTASLAPRMSNQGIAVLNNFVYLIGGDNNVQGFRAESRCWRYDPRHNRWFQIQPLQQEHADLCVCVVGGYIYAVAGRDYHNDLTAVERYDPATNSWAYVAPLKREVYAHAGAALDGKMYVTCGRRGEDYLKETHCYEPGSDTWHTLADGPVRRAWHGMATLLDKLYVIGGSNNDAGYRRDVHQGRPTPPSGCAESIRPLTLGLAKWWPFQVACYSCRSGQWSSVCPLPAGHGEPGIAVLDSRIYVLGGRSHNRGSRTGYVHIYDAGRDRWEEGPQLDNSISGLAACVLTLPRSLLLEPPRGTPDRSQADPDFASEVMSVSDWEEFDNSSED", "length": 661, "header": "tr|A0AAA9THR2-1|A0ABI0NSG8_BOVIN Computationally mapped isoform of Kelch-like protein 22 OS=Bos taurus OX=9913 GN=KLHL22 PE=4 SV=1 CANONICAL=A0ABI0NSG8-1" }, "locus": { "chromosome": "17", "start_pos": 72505325, "end_pos": 72491792, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089108.2", "url": "https://www.ensembl.org/id/ENSBTAT00000089108.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096627.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096627.1" } ] } }, { "isoform_ac": "A0ABI0NSG8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8/entry#A0ABI0NSG8-1", "sequence": { "sequence": "MAEEQEFARLCKLPTQPSHPHCVSSTYRSAQHSQALLRGLLALRDSGILFDVVLVVEGKQLEAHRILLAASCDYFRGMFAGGLKEMEQEEVLIHGVSYNAMCQILHFIYTSELELSLSNVQETLVAACQLQIPEIIHFCCDFLTPWVDEDNILDVYRLAELFDLSRLTEQLDAYILKNFVAFSRTDKYRQLPLEKVYALLSSNRLEVSCETEVYEGALLYHYPPEQVQADRLPLHEPPKLLETVRFPLMEAEVLQRLHDKLEPSPLRDTVAEALMYHRNESLQPSLQGPQTELRSDFQCVVGFGGIHSTPSTVLSDQAKYLNPLLGEWKHFTASLAPRMSNQGIAVLNNFVYLIGGDNNVQGFRAESRCWRYDPRHNRWFQIQPLQQEHADLCVCVVGGYIYAVAGRDYHNDLTAVERYDPATNSWAYVAPLKREVYAHAGAALDGKMYVTCGRRGEDYLKETHCYEPGSDTWHTLADGPVRRAWHGMATLLDKLYVIGGSNNDAGYRRDVHQVACYSCRSGQWSSVCPLPAGHGEPGIAVLDSRIYVLGGRSHNRGSRTGYVHIYDAGRDRWEEGPQLDNSISGLAACVLTLPRSLLLEPPRGTPDRSQADPDFASEVMSVSDWEEFDNSSED", "length": 634, "header": "tr|A0ABI0NSG8-1|A0ABI0NSG8_BOVIN Isoform 1 of Kelch-like protein 22 OS=Bos taurus OX=9913 GN=KLHL22 PE=4 SV=1 CANONICAL=A0ABI0NSG8-1" }, "locus": { "chromosome": "17", "start_pos": 72505325, "end_pos": 72491792, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143467.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143467.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106020.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106020.1" } ] } }, { "isoform_ac": "F1N1V7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8/entry#F1N1V7-1", "sequence": { "sequence": "MSLRKCLTAAELRLGAVVRMAEEQEFARLCKLPTQPSHPHCVSSTYRSAQHSQALLRGLLALRDSGILFDVVLVVEGKQLEAHRILLAASCDYFRGMFAGGLKEMEQEEVLIHGVSYNAMCQILHFIYTSELELSLSNVQETLVAACQLQIPEIIHFCCDFLTPWVDEDNILDVYRLAELFDLSRLTEQLDAYILKNFVAFSRTDKYRQLPLEKVYALLSSNRLEVSCETEVYEGALLYHYPPEQVQADRLPLHEPPKLLETVRFPLMEAEVLQRLHDKLEPSPLRDTVAEALMYHRNESLQPSLQGPQTELRSDFQCVVGFGGIHSTPSTVLSDQAKYLNPLLGEWKHFTASLAPRMSNQGIAVLNNFVYLIGGDNNVQGFRAESRCWRYDPRHNRWFQIQPLQQEHADLCVCVVGGYIYAVAGRDYHNDLTAVERYDPATNSWAYVAPLKREVYAHAGAALDGKMYVTCGRRGEDYLKETHCYEPGSDTWHTLADGPVRRAWHGMATLLDKLYVIGGSNNDAGYRRDVHQVACYSCRSGQWSSVCPLPAGHGEPGIAVLDSRIYVLGGRSHNRGSRTGYVHIYDAGRDRWEEGPQLDNSISGLAACVLTLPRSLLLEPPRGTPDRSQADPDFASEVMSVSDWEEFDNSSED", "length": 653, "header": "tr|F1N1V7-1|A0ABI0NSG8_BOVIN Computationally mapped isoform of Kelch-like protein 22 OS=Bos taurus OX=9913 GN=KLHL22 PE=4 SV=2 CANONICAL=A0ABI0NSG8-1" }, "locus": { "chromosome": "17", "start_pos": 72505325, "end_pos": 72490080, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026853.6", "url": "https://www.ensembl.org/id/ENSBTAT00000026853.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026853.5", "url": "https://www.ensembl.org/id/ENSBTAP00000026853.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540134", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540134", "resource": "KEGG Pathway" }, { "id": "R-BTA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "positive regulation of T cell mediated immune response to tumor cell", "id": "GO:0002842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002842", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "positive regulation of T cell activation", "id": "GO:0050870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050870", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "cellular response to L-leucine", "id": "GO:0071233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071233", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "negative regulation of type I interferon production", "id": "GO:0032480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032480", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "cellular response to amino acid stimulus", "id": "GO:0071230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071230", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "polar microtubule", "id": "GO:0005827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005827", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "14-3-3 protein binding", "id": "GO:0071889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071889", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NSG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG8" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 117, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 279, "end_pos": 281 }, { "start_pos": 630, "end_pos": 632 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NSG5-1", "uniprot_ac": "A0ABI0NSG5", "uniprot_id": "A0ABI0NSG5_BOVIN", "mass": { "chemical_mass": 54000.0, "monoisotopic_mass": 54000.0 }, "refseq": {}, "gene_names": [ { "name": "WDR37", "type": "recommended", "evidence": [ { "id": "A0ABI0NSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG5" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 37", "type": "recommended", "evidence": [ { "id": "A0ABI0NSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for normal ER Ca2+ handling in lymphocytes. Together with PACS1, it plays an essential role in stabilizing peripheral lymphocyte populations.", "evidence": [ { "database": "UniProtKB", "id": "E1B9V7", "url": "https://www.uniprot.org/uniprotkb/E1B9V7#function" }, { "database": "UniProtKB", "id": "ARBA00054260", "url": "https://www.uniprot.org/uniprotkb/ARBA00054260#function" }, { "database": "UniProtKB", "id": "A0AAA9RXU6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXU6#function" }, { "database": "UniProtKB", "id": "A0AAA9T9A2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9A2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "WDR37", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG5", "locus": { "chromosome": "13", "start_pos": 46279117, "end_pos": 46322491, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000683", "url": "https://www.ensembl.org/id/ENSBTAG00000000683" } ] } } ], "crossref": [ { "id": "ENSBTAG00000000683", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000683", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "529876", "url": "https://www.ncbi.nlm.nih.gov/gene/529876", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1B9V7", "url": "https://www.orthodb.org/?gene=E1B9V7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19855", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19855", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19855:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19855:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9RXU6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXU6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T9A2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T9A2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRF3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRF3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTD4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTD4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSG5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSG5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B9V7", "url": "https://www.uniprot.org/uniprotkb/E1B9V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B9V7-1", "url": "https://www.uniprot.org/uniprotkb/E1B9V7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPRDMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREVETLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYIGHRDGIWDVSVARTQPVVLGTASADHTALLWSIETGRSLAKYTGHVGSVNSIKFHPSEQLALTASGDQTAHVWRYAVQLPAPQPAADSSQQLCGEDEVECSDKDEPDADADASSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQVRAGAAYAGGWGRGPLSDVGSSQPAWLCSVLQEPLLKERS", "length": 493, "header": "tr|A0ABI0NSG5-1|A0ABI0NSG5_BOVIN Isoform 1 of WD repeat-containing protein 37 OS=Bos taurus OX=9913 GN=WDR37 PE=4 SV=1 CANONICAL=A0ABI0NSG5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RXU6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG5/entry#A0AAA9RXU6-1", "sequence": { "sequence": "MPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPRDMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLESSHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYIGHRDGIWDVSVARTQPVVLGTASADHTALLWSIETGRSLAKYTGHVGSVNSIKFHPSEQLALTASGDQTAHVWRYAVQLPAPQPAADSSQLCGEDEVECSDKDEPDADADASSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCGSAWSEDHPVCNLFTCGFDRQAIGWNINIPALLQEK", "length": 463, "header": "tr|A0AAA9RXU6-1|A0ABI0NSG5_BOVIN Computationally mapped isoform of WD repeat-containing protein 37 OS=Bos taurus OX=9913 GN=WDR37 PE=4 SV=1 CANONICAL=A0ABI0NSG5-1" }, "locus": { "chromosome": "13", "start_pos": 46312006, "end_pos": 46290026, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089123.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089123.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074637.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074637.1" } ] } }, { "isoform_ac": "A0AAA9T9A2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG5/entry#A0AAA9T9A2-1", "sequence": { "sequence": "SDLAAAELQEVSSLLCLEHSGCEDCEDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREVETLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYIGHRDGIWDVSVARTQPVVLGTASADHTALLWSIETGRSLAKYTGHVGSVNSIKFHPSEQLALTASGDQTAHVWRYAVQLPAPQPAADSSQLCGEDEVECSDKDEPDADADASSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCGSAWSEDHPVCNLFTCGFDRQAIGWNINIPALLQEK", "length": 475, "header": "tr|A0AAA9T9A2-1|A0ABI0NSG5_BOVIN Computationally mapped isoform of WD repeat-containing protein 37 OS=Bos taurus OX=9913 GN=WDR37 PE=4 SV=1 CANONICAL=A0ABI0NSG5-1" }, "locus": { "chromosome": "13", "start_pos": 46309230, "end_pos": 46290026, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129979.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129979.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093199.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093199.1" } ] } }, { "isoform_ac": "A0AAA9TRF3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG5/entry#A0AAA9TRF3-1", "sequence": { "sequence": "MPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPRDMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREVETLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYIGHRDGIWDVSVARTQPVVLGTASADHTALLWSIETGRSLAKYTGHVGSVNSIKFHPSEQLALTASGDQTAHVWRYAVQLPAPQPAADSSQLCGEDEVECSDKDEPDADADASSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQADFSPAEPPGKPQVTVQTASTH", "length": 474, "header": "tr|A0AAA9TRF3-1|A0ABI0NSG5_BOVIN Computationally mapped isoform of WD repeat-containing protein 37 OS=Bos taurus OX=9913 GN=WDR37 PE=4 SV=1 CANONICAL=A0ABI0NSG5-1" }, "locus": { "chromosome": "13", "start_pos": 46312006, "end_pos": 46279154, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118096.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118096.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099893.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099893.1" } ] } }, { "isoform_ac": "A0AAA9TTD4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG5/entry#A0AAA9TTD4-1", "sequence": { "sequence": "MPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPRDMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREVETLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYIGHRDGIWDVSVARTQPVVLGTASADHTALLWSIETGRSLAKYTGHVGSVNSIKFHPSEQLALTASGDQTAHVWRYAVQLPAPQPAADSSQLCGEDEVECSDKDEPDADADASSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQVSIRSTWSFDSRALGPSEQRGVSGSMDLMGVLWALHSPAP", "length": 492, "header": "tr|A0AAA9TTD4-1|A0ABI0NSG5_BOVIN Computationally mapped isoform of WD repeat-containing protein 37 OS=Bos taurus OX=9913 GN=WDR37 PE=4 SV=1 CANONICAL=A0ABI0NSG5-1" }, "locus": { "chromosome": "13", "start_pos": 46312006, "end_pos": 46290993, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101179.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101179.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100334.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100334.1" } ] } }, { "isoform_ac": "A0ABI0NSG5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG5/entry#A0ABI0NSG5-1", "sequence": { "sequence": "MPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPRDMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREVETLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYIGHRDGIWDVSVARTQPVVLGTASADHTALLWSIETGRSLAKYTGHVGSVNSIKFHPSEQLALTASGDQTAHVWRYAVQLPAPQPAADSSQQLCGEDEVECSDKDEPDADADASSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQVRAGAAYAGGWGRGPLSDVGSSQPAWLCSVLQEPLLKERS", "length": 493, "header": "tr|A0ABI0NSG5-1|A0ABI0NSG5_BOVIN Isoform 1 of WD repeat-containing protein 37 OS=Bos taurus OX=9913 GN=WDR37 PE=4 SV=1 CANONICAL=A0ABI0NSG5-1" }, "locus": { "chromosome": "13", "start_pos": 46312006, "end_pos": 46291216, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139764.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139764.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105910.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105910.1" } ] } }, { "isoform_ac": "E1B9V7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG5/entry#E1B9V7-1", "sequence": { "sequence": "MPTESGSCSAARQAKQKRKSHSLSIRRTNSSEQERTGLPRDMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREVETLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAVCQLVKEYIGHRDGIWDVSVARTQPVVLGTASADHTALLWSIETGRSLAKYTGHVGSASGDQTAHVWRYAVQLPAPQPAADSSQQLCGEDEVECSDKDEPDADADASSDCPTIRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCGSAWSEDHPVCNLFTCGFDRQAIGWNINIPALLQEK", "length": 481, "header": "tr|E1B9V7-1|A0ABI0NSG5_BOVIN Computationally mapped isoform of WD repeat-containing protein 37 OS=Bos taurus OX=9913 GN=WDR37 PE=4 SV=4 CANONICAL=A0ABI0NSG5-1" }, "locus": { "chromosome": "13", "start_pos": 46312006, "end_pos": 46290026, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000906.7", "url": "https://www.ensembl.org/id/ENSBTAT00000000906.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000906.7", "url": "https://www.ensembl.org/id/ENSBTAP00000000906.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQI4-1", "uniprot_ac": "A0ABI0NQI4", "uniprot_id": "A0ABI0NQI4_BOVIN", "mass": { "chemical_mass": 30867.0, "monoisotopic_mass": 30867.0 }, "refseq": { "ac": "XP_024846874", "name": "coiled-coil domain-containing protein 201", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024846874" }, "gene_names": [ { "name": "CCDC201", "type": "recommended", "evidence": [ { "id": "A0ABI0NQI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQI4" } ] }, { "name": "CCDC201", "type": "synonym", "evidence": [ { "id": "XP_024846874", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024846874" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 201", "type": "recommended", "evidence": [ { "id": "A0ABI0NQI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQI4/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 201", "type": "synonym", "evidence": [ { "id": "XP_024846874", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024846874" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQI4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQI4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC201", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQI4", "locus": { "chromosome": "4", "start_pos": 76157435, "end_pos": 76150320, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000053893", "url": "https://www.ensembl.org/id/ENSBTAG00000053893" } ] } } ], "crossref": [ { "id": "112446404", "url": "https://www.ncbi.nlm.nih.gov/gene/112446404", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "XP_024846874", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024846874", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S3J7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3J7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3J7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQI4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQI4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLWTHTADFTMFLFTNTNKRGLHYAQSSVPKCHEVRRTVGVYRCSSKTLTQTSGHWGGVQEAPTLFVQDFGQTLPLCSPQFPHLENDPLYQASGLSSPEDESLSSVTRRSSLRWALKHSTPAGAALSWHSGLQGDVPSHQERGPAGRSPRPARSSWDLLSSPGGVSLMASFRKRRLSTIKASEVSSEQLGSNSDPFAFEEDPPVPASVTQQQQQGKSPPARRSPPNLGLPGIPDTARRRPRDLKRLAAMTERVRQWEIHLLQNIEEATQHELTIEDD", "length": 278, "header": "tr|A0ABI0NQI4-1|A0ABI0NQI4_BOVIN Isoform 1 of Coiled-coil domain containing 201 OS=Bos taurus OX=9913 GN=CCDC201 PE=4 SV=1 CANONICAL=A0ABI0NQI4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S3J7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQI4/entry#A0AAA9S3J7-1", "sequence": { "sequence": "MERGAKASGLSSPEDESLSSVTRRSSLRWALKHSTPAGAALSWHSGLQGDVPSHQERGPAGRSPRPARSSWDLLSSPGGVSLMASFRKRRLSTIKASEVSSEQLGSNSDPFAFEEDPPVPASVTQQQQQGKSPPARRSPPNLGLPGIPDTARRRPRDLKRLAAMTERVRQWEIHLLQNIEEATQHELTIEDD", "length": 192, "header": "tr|A0AAA9S3J7-1|A0ABI0NQI4_BOVIN Computationally mapped isoform of Coiled-coil domain containing 201 OS=Bos taurus OX=9913 GN=CCDC201 PE=4 SV=2 CANONICAL=A0ABI0NQI4-1" }, "locus": { "chromosome": "4", "start_pos": 76156431, "end_pos": 76150519, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076847.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076847.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080512.2", "url": "https://www.ensembl.org/id/ENSBTAP00000080512.2" } ] } }, { "isoform_ac": "A0ABI0NQI4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQI4/entry#A0ABI0NQI4-1", "sequence": { "sequence": "MRLWTHTADFTMFLFTNTNKRGLHYAQSSVPKCHEVRRTVGVYRCSSKTLTQTSGHWGGVQEAPTLFVQDFGQTLPLCSPQFPHLENDPLYQASGLSSPEDESLSSVTRRSSLRWALKHSTPAGAALSWHSGLQGDVPSHQERGPAGRSPRPARSSWDLLSSPGGVSLMASFRKRRLSTIKASEVSSEQLGSNSDPFAFEEDPPVPASVTQQQQQGKSPPARRSPPNLGLPGIPDTARRRPRDLKRLAAMTERVRQWEIHLLQNIEEATQHELTIEDD", "length": 278, "header": "tr|A0ABI0NQI4-1|A0ABI0NQI4_BOVIN Isoform 1 of Coiled-coil domain containing 201 OS=Bos taurus OX=9913 GN=CCDC201 PE=4 SV=1 CANONICAL=A0ABI0NQI4-1" }, "locus": { "chromosome": "4", "start_pos": 76156431, "end_pos": 76148702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153035.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153035.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104559.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104559.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], 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"sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NRI1-1", "uniprot_ac": "A0ABI0NRI1", "uniprot_id": "A0ABI0NRI1_BOVIN", "mass": { "chemical_mass": 491396.0, "monoisotopic_mass": 491396.0 }, "refseq": { "ac": "XP_024832180", "name": "intermembrane lipid transfer protein VPS13D isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832180" }, "gene_names": [ { "name": "VPS13D", "type": "recommended", "evidence": [ { "id": "A0ABI0NRI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1" } ] }, { "name": "VPS13D", "type": "synonym", "evidence": [ { "id": "XP_024832180", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832180" } ] } ], "protein_names": [ { "name": "Vacuolar protein sorting 13 homolog D", "type": "synonym", "evidence": [ { "id": "A0ABI0NRI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1/entry#names_and_taxonomy" } ] }, { "name": "intermembrane lipid transfer protein VPS13D isoform 1", "type": "synonym", "evidence": [ { "id": "XP_024832180", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832180" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRI1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "VPS13D", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1", "locus": { "chromosome": "16", "start_pos": 41275830, "end_pos": 41473918, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016080", "url": "https://www.ensembl.org/id/ENSBTAG00000016080" } ] } } ], "crossref": [ { "id": "ENSBTAG00000016080", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016080", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14306", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14306", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23453", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23453", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540683", "url": "https://www.ncbi.nlm.nih.gov/gene/540683", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BIF6", "url": "https://www.orthodb.org/?gene=E1BIF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16166:SF141", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16166:SF141", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12624", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12624", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25033", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25033", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024832180", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832180", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S5Z9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NR57", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NR57-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRI1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRI1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS57", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS57-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1H6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1H6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIF6", "url": "https://www.uniprot.org/uniprotkb/E1BIF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIF6-1", "url": "https://www.uniprot.org/uniprotkb/E1BIF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGLIGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEKWKNERQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVSMQNAMNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQVELQEAMDRSMESRDHHYILEPVCASALLKRNCSKEPLRSRHTPRIECDIHLETIPLKLSQLQYRQIMEFLKELERKERQVKFRKWKPKVAVSENCREWWYFALNANLHEIREQRKRCTWGFLLGRARDAVSYTDKYFTTLRGGLLSADDKEEMYRIEEEQSFEELKILRELVHERFHKQEELAESLREPQLDPLGDSPGDPGPGGGSGMLQYLQSWFPGWGGWYGQQSPEGKPVEGLMAEPQEQWTPEEILGSEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHQEQGAPQMNQSAFMQLEFSGVKLLAESLPRRNSSLLLVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSHHYPAADPDDPVFEMLYERNPVHSHFERRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNRLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTNTQDDSKRKSGDGSALEENQFSDDEYKTPLATPPNTPPPETSSSNGEKTPPFSGVKFSEEQLQAHLMSTKMYERYSLSFLDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTFDSQMKEKIFPQGGQRGSLQDSVMNLTQSIVMLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGSNVAHFTSAATRNNQSATSISLDRVLTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDELSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEIHRLNLLLLRTVGMANGEKYGRKIATASIGGTKVNVSMGNTFDMNGSLGCLQLMDLTQENVKNQYVVSIGNSVGYENIISDIGFYESVFVRMEDAALTDALSFTFVEKSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAATKVTTVLATKTAEYSEMVSLFETPRKARDSFFLEENEPYGFGLGASHSDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLTGREGPGPEMSRAFCPLSGSANANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGASSIMKIEGKFVNPVQVVLAKHVYEQVLQTLDNLVYSEDLNKFPVSAASSPCPNSPLPPLSTCGEPSAERKENGLFSHSSLSNSSQKSLSVKEVKSFTQIQANFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALRSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSCPSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILAGKSKFDDSLVHINVFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKVPPEDVLQNVKSESSALAESELQEPVNTKLDLKVHSLSLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTSHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDVRVSLQMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRYSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFTLQDKESVPSSSPTGTPKRSVRKMTSMEDLKGTHSEGLIMMPPAGMSRGSLKSESVPSTSTKQQGQPATTSVGRASSSPEDHVCLLDCIVVDLQDMDIFAAERHPREYSRVSEDSSGDLIFPSYFVLQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLCKYKLIRGLLENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKGKEAAGSLARFDFKKCKLLYESFSNQTKSVNLVSHSMMAFDTRSAGQKTSPGVTNVFTCIFQPSKSSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKPAKVTPFRHRNSSSESAVIPKTVKSGVVTKRSSLPVSTERHLEVKVNVTGTEFVVVEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHDTALSIVDPVQIHVELVGNSSYQNSSGLMDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDVAALEASSVHSYLPGASRGGEEVREGTRHTLDPVLELQLARLQELGFSTDDCRKALLVCQGQLKKAASWLFKNAEPRTSLSLASNSQQSQGAAPAWLISGVEMKAESVCICFIDDCMDCDVPLAELTFSRLNFLQHVRTSPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKQRLDVNITSVLIDQYISTKESWMADYCKQDKEVDPTPSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEMKAPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTLLDDAHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVKNRLETPMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEVSSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEVALHTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVRMRLYDTNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALRVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPTPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEISCNMNDFQDNQQLYYENFIYIAATYTFSGSSLQEGTGRPVTSNKAVTCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPSEPSAARSAEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFREGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSMQLLGPVPPEQQFINQKMRPGSGMLSIRVVPDGPTRALQITDFSQRKSDRSSYEVDELPVTERELQKLKNPDTEQELEVLVKLEGGIGLSLINKVPEELVFASLTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSTLTNIYKHLMVTAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENLHEKTAEQGGTPIRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKDFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLRSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVNTSSGVSIPGPSHQKPMVHVKSEVLAIKLSQEINYAKSLYYEQQLMLRLSENQEQLELDS", "length": 4391, "header": "tr|A0ABI0NRI1-1|A0ABI0NRI1_BOVIN Isoform 1 of Vacuolar protein sorting 13 homolog D OS=Bos taurus OX=9913 GN=VPS13D PE=3 SV=1 CANONICAL=A0ABI0NRI1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S5Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1/entry#A0AAA9S5Z9-1", "sequence": { "sequence": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGLIGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEKWKNERQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVSMQNAMNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQVELQEAMDRSMESRDHHYILEPVCASALLKRNCSKEPLRSRHTPRIECDIHLETIPLKLSQLQYRQIMEFLKELERKERQVKFRKWKPKVAVSENCREWWYFALNANLHEIREQRKRCTWGFLLGRARDAVSYTDKYFTTLRGGLLSADDKEEMYRIEEEQSFEELKILRELVHERFHKQEELAESLREPQLDPLGDSPGDPGPGGGSGMLQYLQSWFPGWGGWYGQQSPEGKPVEGLMAEPQEQWTPEEILGVKLLAESLPRRNSSLLLVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSHHYPAADPDDPVFEMLYERNPVHSHFERRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNRLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTNTQDDSKRKSGDGSALEENQFSDDEYKTPLATPPNTPPPETSSSNGEKTPPFSGVKFSEEQLQAHLMSTKMYERYSLSFLDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTFDSQMKEKIFPQGGQRGSLQDSVMNLTQSIVMLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGSNVAHFTSAATRNNQSATSISLDRVLTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDELSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEIHRLNLLLLRTVGMANGEKYGRKIATASIGGTKVNVSMGNTFDMNGSLGCLQLMDLTQENVKNQYVVSIGNSVGYENIISDIGFYESVFVRMEDAALTDALSFTFVEKSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAATKVTTVLATKTAEYSEMVSLFETPRKARDSFFLEENEPYGFGLGASHSDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLTGREGPGPEMSRAFCPLSGSANANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGASSIMKIEGKFVNPVQVVLAKHVYEQVLQTLDNLVYSEDLNKFPVSAASSPCPNSPLPPLSTCGEPSAERKENGLFSHSSLSNSSQKSLSVKEVKSFTQIQANFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALRSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSCPSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILAGKSKFDDSLVHINVFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKVPPEDVLQNVKSESSALAESELQEPVNTKLDLKVHSLSLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTSHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDVRVSLQMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRYSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFTLQDKESVPSSSPTGTPKRSVRKMTSMEDLKGTHSEGLIMMPPAGMSRGSLKSESVPSTSTKQQGQPATTSVGRASSSPEDHVCLLDCIVVDLQDMDIFAAERHPREYSRVSEDSSGDLIFPSYFVLQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLCKYKLIRGLLENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKGKEAAGSLARFDFKKCKLLYESFSNQTKSVNLVSHSMMAFDTRSAGQKTSPGVTNVFTCIFQPSKSSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKPAKVTPFRHRNSSSESAVIPKTVKSGVVTKRSSLPVSTERHLEVKVNVTGTEFVVVEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHDTALSIVDPVQIHVELVGNSSYQNSSGLMDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDVAALEASSVHSYLPGASRGGEEVREGTRHTLDPVLELQLARLQELGFSTDDCRKALLVCQGQLKKAASWLFKNAEPRTSLSLASNSQQSQGAAPAWLISGVEMKAESVCICFIDDCMDCDVPLAELTFSRLNFLQHVRTSPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKQRLDVNITSVLIDQYISTKESWMADYCKQDKEVDPTPSEDWMGSSVDPPCFGQKMKAPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTLLDDAHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVKNRLETPMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEVSSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEVALHTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVRMRLYDTNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALRVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPTPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEISCNMNDFQDNQQLYYENFIYIAATYTFSGSSLQEGTGRPVTSNKAVTCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPSEPSAARSAEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFREGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSMQLLGPVPPEQQFINQKMRPGSGMLSIRVVPDGPTRALQITDFSQRKSDRSSYEVDELPVTERELQKLKNPDTEQELEVLVKLEGGIGLSLINKVPEELVFASLTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSTLTNIYKHLMVTAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENLHEKTAEQGGTPIRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKDFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLRSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVNTSSGVSIPGPSHQKPMVHVKSEVLAIKLSQEINYAKSLYYEQQLMLRLSENQEQLELDS", "length": 4305, "header": "tr|A0AAA9S5Z9-1|A0ABI0NRI1_BOVIN Computationally mapped isoform of Vacuolar protein sorting 13 homolog D OS=Bos taurus OX=9913 GN=VPS13D PE=3 SV=2 CANONICAL=A0ABI0NRI1-1" }, "locus": { "chromosome": "16", "start_pos": 41473842, "end_pos": 41208289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125375.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125375.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080645.2", "url": "https://www.ensembl.org/id/ENSBTAP00000080645.2" } ] } }, { "isoform_ac": "A0ABI0NR57-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1/entry#A0ABI0NR57-1", "sequence": { "sequence": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGLIGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEKWKNERQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVSMQNAMNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQVELQEAMDRSMESRDHHYILEPVCASALLKRNCSKEPLRSRHTPRIECDIHLETIPLKLSQLQYRQIMEFLKELERKERQVKFRKWKPKVAVSENCREWWYFALNANLHEIREQRKRCTWGFLLGRARDAVSYTDKYFTTLRGGLLSADDKEEMYRIEEEQSFEELKILRELVHERFHKQEELAESLREPQLDPLGDSPGDPGPGGGSGMLQYLQSWFPGWGGWYGQQSPEGKPVEGLMAEPQEQWTPEEILGSEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHQEQGAPQMNQSAFMQLEFSGVKLLAESLPRRNSSLLLVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSHHYPAADPDDPVFEMLYERNPVHSHFERRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNRLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTNTQDDSKRKSGDGSALEENQFSDDEYKTPLATPPNTPPPETSSSNGEKTPPFSGVKFSEEQLQAHLMSTKMYERYSLSFLDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTFDSQMKEKIFPQGGQRGSLQDSVMNLTQSIVMLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGSNVAHFTSAATRNNQSATSISLDRVLTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDELSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEIHRLNLLLLRTVGMANGEKYGRKIATASIGGTKVNVSMGNTFDMNGSLGCLQLMDLTQENVKNQYVVSIGNSVGYENIISDIGFYESVFVRMEDAALTDALSFTFVEKSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAATKVTTVLATKTAEYSEMVSLFETPRKARDSFFLEENEPYGFGLGASHSDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLTGREGPGPEMSRAFCPLSGSANANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGASSIMKIEGKFVNPVQVVLAKHVYEQVLQTLDNLVYSEDLNKFPVSAASSPCPNSPLPPLSTCGEPSAERKENGLFSHSSLSNSSQKSLSVKEVKSFTQIQANFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALRSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSCPSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILAGKSKFDDSLVHINVFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKVPPEDVLQNVKSESSALAESELQEPVNTKLDLKVHSLSLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTSHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDVRVSLQMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRYSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFTLQDKESVPSSSPTGTPKRSVRKMTSMEDLKGTHSEGLIMMPPAGMSRGSLKSESVPSTSTKQQGQPATTSVGRASSSPEDHVCLLDCIVVDLQDMDIFAAERHPREYSRVSEDSSGDLIFPSYFVLQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLCKYKLIRGLLENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKGKEAAGSLARFDFKKCKLLYESFSNQTKSVNLVSHSMMAFDTRSAGQKTSPGVTNVFTCIFQPSKSSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKPAKVTPFRHRNSSSESAVIPKTVKSGVVTKRSSLPVSTERHLEVKVNVTGTEFVVVEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHDTALSIVDPVQIHVELVGNSSYQNSSGLMDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDVAALEASSVHSYLPGASRGGEEVREGTRHTLDPVLELQLARLQELGFSTDDCRKALLVCQGQLKKAASWLFKNAEPRTSLSLASNSQQSQGAAPAWLISGVEMKAESVCICFIDDCMDCDVPLAELTFSRLNFLQHVRTSPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKQRLDVNITSVLIDQYISTKESWMADYCKQDKEVDPTPSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYAREMKAPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTLLDDAHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVKNRLETPMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEVSSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEVALHTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVRMRLYDTNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALRVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPTPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEISCNMNDFQDNQQLYYENFIYIAATYTFSGSSLQEGTGRPVTSNKAVTCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPSEPSAARSAEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFREGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSMQLLGPVPPEQQFINQKMRPGSGMLSIRVVPDGPTRALQITDFSQRKSDRSSYEVDELPVTERELQKLKNPDTEQELEVLVKLEGGIGLSLINKVPEELVFASLTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSTLTNIYKHLMVTAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENLHEKTAEQGGTPIRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKDFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLRSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVNTSSGVSIPGPSHQKPMVHVKSEVLAIKLSQEINYAKSLYYEQQLMLRLSENQEQLELDS", "length": 4390, "header": "tr|A0ABI0NR57-1|A0ABI0NR57_BOVIN Computationally mapped isoform of Vacuolar protein sorting 13 homolog D OS=Bos taurus OX=9913 GN=VPS13D PE=3 SV=1 CANONICAL=A0ABI0NRI1-1" }, "locus": { "chromosome": "16", "start_pos": 41473842, "end_pos": 41208289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146119.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146119.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106026.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106026.1" } ] } }, { "isoform_ac": "A0ABI0NRI1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1/entry#A0ABI0NRI1-1", "sequence": { "sequence": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGLIGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEKWKNERQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVSMQNAMNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQVELQEAMDRSMESRDHHYILEPVCASALLKRNCSKEPLRSRHTPRIECDIHLETIPLKLSQLQYRQIMEFLKELERKERQVKFRKWKPKVAVSENCREWWYFALNANLHEIREQRKRCTWGFLLGRARDAVSYTDKYFTTLRGGLLSADDKEEMYRIEEEQSFEELKILRELVHERFHKQEELAESLREPQLDPLGDSPGDPGPGGGSGMLQYLQSWFPGWGGWYGQQSPEGKPVEGLMAEPQEQWTPEEILGSEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHQEQGAPQMNQSAFMQLEFSGVKLLAESLPRRNSSLLLVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSHHYPAADPDDPVFEMLYERNPVHSHFERRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNRLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTNTQDDSKRKSGDGSALEENQFSDDEYKTPLATPPNTPPPETSSSNGEKTPPFSGVKFSEEQLQAHLMSTKMYERYSLSFLDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTFDSQMKEKIFPQGGQRGSLQDSVMNLTQSIVMLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGSNVAHFTSAATRNNQSATSISLDRVLTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDELSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEIHRLNLLLLRTVGMANGEKYGRKIATASIGGTKVNVSMGNTFDMNGSLGCLQLMDLTQENVKNQYVVSIGNSVGYENIISDIGFYESVFVRMEDAALTDALSFTFVEKSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAATKVTTVLATKTAEYSEMVSLFETPRKARDSFFLEENEPYGFGLGASHSDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLTGREGPGPEMSRAFCPLSGSANANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGASSIMKIEGKFVNPVQVVLAKHVYEQVLQTLDNLVYSEDLNKFPVSAASSPCPNSPLPPLSTCGEPSAERKENGLFSHSSLSNSSQKSLSVKEVKSFTQIQANFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALRSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSCPSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILAGKSKFDDSLVHINVFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKVPPEDVLQNVKSESSALAESELQEPVNTKLDLKVHSLSLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTSHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDVRVSLQMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRYSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFTLQDKESVPSSSPTGTPKRSVRKMTSMEDLKGTHSEGLIMMPPAGMSRGSLKSESVPSTSTKQQGQPATTSVGRASSSPEDHVCLLDCIVVDLQDMDIFAAERHPREYSRVSEDSSGDLIFPSYFVLQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLCKYKLIRGLLENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKGKEAAGSLARFDFKKCKLLYESFSNQTKSVNLVSHSMMAFDTRSAGQKTSPGVTNVFTCIFQPSKSSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKPAKVTPFRHRNSSSESAVIPKTVKSGVVTKRSSLPVSTERHLEVKVNVTGTEFVVVEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHDTALSIVDPVQIHVELVGNSSYQNSSGLMDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDVAALEASSVHSYLPGASRGGEEVREGTRHTLDPVLELQLARLQELGFSTDDCRKALLVCQGQLKKAASWLFKNAEPRTSLSLASNSQQSQGAAPAWLISGVEMKAESVCICFIDDCMDCDVPLAELTFSRLNFLQHVRTSPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKQRLDVNITSVLIDQYISTKESWMADYCKQDKEVDPTPSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYARAEMKAPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTLLDDAHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVKNRLETPMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEVSSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEVALHTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVRMRLYDTNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALRVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPTPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEISCNMNDFQDNQQLYYENFIYIAATYTFSGSSLQEGTGRPVTSNKAVTCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPSEPSAARSAEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFREGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSMQLLGPVPPEQQFINQKMRPGSGMLSIRVVPDGPTRALQITDFSQRKSDRSSYEVDELPVTERELQKLKNPDTEQELEVLVKLEGGIGLSLINKVPEELVFASLTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSTLTNIYKHLMVTAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENLHEKTAEQGGTPIRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKDFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLRSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVNTSSGVSIPGPSHQKPMVHVKSEVLAIKLSQEINYAKSLYYEQQLMLRLSENQEQLELDS", "length": 4391, "header": "tr|A0ABI0NRI1-1|A0ABI0NRI1_BOVIN Isoform 1 of Vacuolar protein sorting 13 homolog D OS=Bos taurus OX=9913 GN=VPS13D PE=3 SV=1 CANONICAL=A0ABI0NRI1-1" }, "locus": { "chromosome": "16", "start_pos": 41473842, "end_pos": 41208289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150480.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150480.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106333.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106333.1" } ] } }, { "isoform_ac": "A0ABI0NS57-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1/entry#A0ABI0NS57-1", "sequence": { "sequence": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGLIGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEKWKNERQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVSMQNAMNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQVELQEAMDRSMESRDHHYILEPVCASALLKRNCSKEPLRSRHTPRIECDIHLETIPLKLSQLQYRQIMEFLKELERKERQVKFRKWKPKVAVSENCREWWYFALNANLHEIREQRKRCTWGFLLGRARDAVSYTDKYFTTLRGGLLSADDKEEMYRIEEEQSFEELKILRELVHERFHKQEELAESLREPQLDPLGDSPGDPGPGGGSGMLQYLQSWFPGWGGWYGQQSPEGKPVEGLMAEPQEQWTPEEILGSEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHQEQGAPQMNQSAFMQLEFSGVKLLAESLPRRNSSLLLVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSHHYPAADPDDPVFEMLYERNPVHSHFERRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNRLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTNTQDDSKRKSGDGSALEENQFSDDEYKTPLATPPNTPPPETSSSNGEKTPPFSGVKFSEEQLQAHLMSTKMYERYSLSFLDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTFDSQMKEKIFPQGGQRGSLQDSVMNLTQSIVMLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGSNVAHFTSAATRNNQSATSISLDRVLTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDELSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEIHRLNLLLLRTVGMANGEKYGRKIATASIGGTKVNVSMGNTFDMNGSLGCLQLMDLTQENVKNQYVVSIGNSVGYENIISDIGFYESVFVRMEDAALTDALSFTFVEKSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAATKVTTVLATKTAEYSEMVSLFETPRKARDSFFLEENEPYGFGLGASHSDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLTGREGPGPEMSRAFCPLSGSANANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGASSIMKIEGKFVNPVQVVLAKHVYEQVLQTLDNLVYSEDLNKFPVSAASSPCPNSPLPPLSTCGEPSAERKENGLFSHSSLSNSSQKSLSVKEVKSFTQIQANFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALRSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSCPSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILAGKSKFDDSLVHINVFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKVPPEDVLQNVKSESSALAESELQEPVNTKLDLKVHSLSLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTSHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDVRVSLQMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRYSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFTLQDKESVPSSSPTGTPKRSVRKMTSMEDLKGTHSEGLIMMPPAGMSRGSLKSESVPSTSTKQQGQPATTSVGRASSSPEDHVCLLDCIVVDLQDMDIFAAERHPREYSRVSEDSSGDLIFPSYFVLQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLCKYKLIRGLLENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKGKEAAGSLARFDFKKCKLLYESFSNQTKSVNLVSHSMMAFDTRSAGQKTSPGVTNVFTCIFQPSKSSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKPAKVTPFRHRNSSSESAVIPKTVKSGVVTKRSSLPVSTERHLEVKVNVTGTEFVVVEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHDTALSIVDPVQIHVELVGNSSYQNSSGLMDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDVAALEASSVHSYLPGASRGGEEVREGTRHTLDPVLELQLARLQELGFSTDDCRKALLVCQGQLKKAASWLFKNAEPRTSLSLASNSQQSQGAAPAWLISGVEMKAESVCICFIDDCMDCDVPLAELTFSRLNFLQHVRTSPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKQRLDVNITSVLIDQYISTKESWMADYCKQDKEVDPTPSEDWMGSSVDPPCFGQTEMKAPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTLLDDAHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVKNRLETPMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEVSSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEVALHTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVRMRLYDTNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALRVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPTPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEISCNMNDFQDNQQLYYENFIYIAATYTFSGSSLQEGTGRPVTSNKAVTCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPSEPSAARSAEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFREGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSMQLLGPVPPEQQFINQKMRPGSGMLSIRVVPDGPTRALQITDFSQRKSDRSSYEVDELPVTERELQKLKNPDTEQELEVLVKLEGGIGLSLINKVPEELVFASLTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSTLTNIYKHLMVTAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENLHEKTAEQGGTPIRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKDFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLRSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVNTSSGVSIPGPSHQKPMVHVKSEVLAIKLSQEINYAKSLYYEQQLMLRLSENQEQLELDS", "length": 4366, "header": "tr|A0ABI0NS57-1|A0ABI0NS57_BOVIN Computationally mapped isoform of Vacuolar protein sorting 13 homolog D OS=Bos taurus OX=9913 GN=VPS13D PE=3 SV=1 CANONICAL=A0ABI0NRI1-1" }, "locus": { "chromosome": "16", "start_pos": 41473842, "end_pos": 41208289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146527.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146527.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106713.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106713.1" } ] } }, { "isoform_ac": "A0ABI0P1H6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1/entry#A0ABI0P1H6-1", "sequence": { "sequence": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGLIGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEKWKNERQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVSMQNAMNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQVELQEAMDRSMESRDHHYILEPVCASALLKRNCSKEPLRSRHTPRIECDIHLETIPLKLSQLQYRQIMEFLKELERKERQVKFRKWKPKVAVSENCREWWYFALNANLHEIREQRKRCTWGFLLGRARDAVSYTDKYFTTLRGGLLSADDKEEMYRIEEEQSFEELKILRELVHERFHKQEELAESLREPQLDPLGDSPGDPGPGGGSGMLQYLQSWFPGWGGWYGQQSPEGKPVEGLMAEPQEQWTPEEILGSEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHQEQGAPQMNQSAFMQLEFSGVKLLAESLPRRNSSLLLVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSHHYPAADPDDPVFEMLYERNPVHSHFERRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNRLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTNTQDDSKRKSGDGSALEENQFSDDEYKTPLATPPNTPPPETSSSNGEKTPPFSGVKFSEEQLQAHLMSTKMYERYSLSFLDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTFDSQMKEKIFPQGGQRGSLQDSVMNLTQSIVMLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGSNVAHFTSAATRNNQSATSISLDRVLTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDELSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEIHRLNLLLLRTVGMANGEKYGRKIATASIGGTKVNVSMGNTFDMNGSLGCLQLMDLTQENVKNQYVVSIGNSVGYENIISDIGFYESVFVRMEDAALTDALSFTFVEKSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAATKVTTVLATKTAEYSEMVSLFETPRKARDSFFLEENEPYGFGLGASHSDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLTGREGPGPEMSRAFCPLSGSANANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGASSIMKIEGKFVNPVQVVLAKHVYEQVLQTLDNLVYSEDLNKFPVSAASSPCPNSPLPPLSTCGEPSAERKENGLFSHSSLSNSSQKSLSVKEVKSFTQIQANFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALRSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSCPSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILAGKSKFDDSLVHINVFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKVPPEDVLQNVKSESSALAESELQEPVNTKLDLKVHSLSLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTSHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDVRVSLQMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRYSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFTLQDKESVPSSSPTGTPKRSVRKMTSMEDLKGTHSEGLIMMPPAGMSRGSLKSESVPSTSTKQQGQPATTSVGRASSSPEDHVCLLDCIVVDLQDMDIFAAERHPREYSRVSEDSSGDLIFPSYFVLQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLCKYKLIRGLLENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKGKEAAGSLARFDFKKCKLLYESFSNQTKSVNLVSHSMMAFDTRSAGQKTSPGVTNVFTCIFQPSKSSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKPAKVTPFRHRNSSSESAVIPKTVKSGVVTKRSSLPVSTERHLEVKVNVTGTEFVVVEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHDTALSIVDPVQIHVELVGNSSYQNSSGLMDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDVAALEASSVHSYLPGASRGGEEVREGTRHTLDPVLELQLARLQELGFSTDDCRKALLVCQGQLKKAASWLFKNAEPRTSLSLASNSQQSQGAAPAWLISGVEMKAESVCICFIDDCMDCDVPLAELTFSRLNFLQHVRTSPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKQRLDVNITSVLIAEMKAPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTLLDDAHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVKNRLETPMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEVSSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEVALHTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVRMRLYDTNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALRVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPTPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEISCNMNDFQDNQQLYYENFIYIAATYTFSGSSLQEGTGRPVTSNKAVTCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPSEPSAARSAEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFREGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSMQLLGPVPPEQQFINQKMRPGSGMLSIRVVPDGPTRALQITDFSQRKSDRSSYEVDELPVTERELQKLKNPDTEQELEVLVKLEGGIGLSLINKVPEELVFASLTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSTLTNIYKHLMVTAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENLHEKTAEQGGTPIRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKDFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVRKPRCCTGPQGLLPRYSESQAEGQEQLFKLTDNIQDEFFIAVENIDSYCVLISSKAVYFLRSGDYVDREAIFLEVKYDDLYHCLVSKDHGKVYVQVTKKAVNTSSGVSIPGPSHQKPMVHVKSEVLAIKLSQEINYAKSLYYEQQLMLRLSENQEQLELDS", "length": 4325, "header": "tr|A0ABI0P1H6-1|A0ABI0P1H6_BOVIN Computationally mapped isoform of Vacuolar protein sorting 13 homolog D OS=Bos taurus OX=9913 GN=VPS13D PE=3 SV=1 CANONICAL=A0ABI0NRI1-1" }, "locus": { "chromosome": "16", "start_pos": 41473842, "end_pos": 41208289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152902.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152902.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104241.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104241.1" } ] } }, { "isoform_ac": "E1BIF6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1/entry#E1BIF6-1", "sequence": { "sequence": "MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGLIGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEKWKNERQQKGESYWYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGICIKNVSMQNAMNEPVQKLMRKKQLDVAEFSIYWDVDCTLLGDLPQVELQEAMDRSMESRDHHYILEPVCASALLKRNCSKEPLRSRHTPRIECDIHLETIPLKLSQLQYRQIMEFLKELERKERQVKFRKWKPKVAVSENCREWWYFALNANLHEIREQRKRCTWGFLLGRARDAVSYTDKYFTTLRGGLLSADDKEEMYRIEEEQSFEELKILRELVHERFHKQEELAESLREPQLDPLGDSPGDPGPGGGSGMLQYLQSWFPGWGGWYGQQSPEGKPVEGLMAEPQEQWTPEEILGSEEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLHQEQGAPQMNQSAFMQLEFSGVKLLAESLPRRNSSLLLVRLGGLFLRDLATEGTMFPLLVFPNPQKEVGRVSQSFGLQTTSADRSHHYPAADPDDPVFEMLYERNPVHSHFERRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNRLKMQTKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTNTQDDSKRKSGDGSALEENQFSDDEYKTPLATPPNTPPPETSSSNGEKTPPFSGVKFSEEQLQAHLMSTKMYERYSLSFLDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLIYTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTFDSQMKEKIFPQGGQRGSLQDSVMNLTQSIVMLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGTNAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNLSFDIPTGSLRDSRAQSPVSGSNVAHFTSAATRNNQSATSISLDRVLTKEQESLIKLEYQFVSSECPSMNLDSTLQVISLQVNNLDIILNPETIVELIGFLQKSFPKEKDELSPQPLMTDFERSFREQGTYQSTYEQNTEVAVEIHRLNLLLLRTVGMANGEKYGRKIATASIGGTKVNVSMGNTFDMNGSLGCLQLMDLTQENVKNQYVVSIGNSVGYENIISDIGFYESVFVRMEDAALTDALSFTFVEKSKQECFLNLKMASLHYNHSAKFLKELTLSMDELEENFRSMLKSAATKVTTVLATKTAEYSEMVSLFETPRKARDSFFLEENEPYGFGLGASHSDTVKLILNINIESPVVSIPRKPGSPELLVGHLGQIFIQNFVAGDDESRSDRLQVEIKDIKLYSLNCTQLTGREGPGPEMSRAFCPLSGSANANSQEEAHFTRHDFFESLHRGQAFHILNNTTIQFKLEKIPIERESELTFSLSPDDLGASSIMKIEGKFVNPVQVVLAKHVYEQVLQTLDNLVYSEDLNKFPVSAASSPCPNSPLPPLSTCGEPSAERKENGLFSHSSLSNSSQKSLSVKEVKSFTQIQANFCISELQVQLSGDLTLGAQGLVSLKFQDFEVEFSKDHPQTLSIQIALRSLLMEDLLEKNPDSKYKNLMVSRGAPKPSSLAQKEYLSQSCPSVSNVEYPDMPRSLPSHMEEAPNVFQLYQRPTSASRKKQKEVQDKDYPLTPPPSPTVDEPKILAGKSKFDDSLVHINVFLVDKKHPEFSSSYNRVNRSIDVDFNCLDVLITLQTWVVILDFFGIGSTADNHAMKVPPEDVLQNVKSESSALAESELQEPVNTKLDLKVHSLSLVLNKTTSELAKANVSKLVAHLEMIEGDLALQGSIGSLSLSDLTSHGEFYRERFTTSGEEALIFQTFKYGRPDPLLRREHDVRVSLQMASVQYVHTQRFQAEVVAFIQHFTQLQDVLGRQRAAIEGQTVRDQAQRYSRVLLDIEAGAPVLLIPESSRSNNLIVANLGKLKVKNKFLFAGFPGTFTLQDKESVPSSSPTGTPKRSVRKMTSMEDLKGTHSEGLIMMPPAGMSRGSLKSESVPSTSTKQQGQPATTSVGRASSSPEDHVCLLDCIVVDLQDMDIFAAERHPREYSRVSEDSSGDLIFPSYFVLQTGGSLLTEPCRLKLQVERNLDKEISHTVPDISIHGNLSSVHCSLDLCKYKLIRGLLENNLGEPIEEFMRPYDLQDPRIHTVLSGEVYTCMCFLIDMVNVSLELKDPKGKEAAGSLARFDFKKCKLLYESFSNQTKSVNLVSHSMMAFDTRSAGQKTSPGVTNVFTCIFQPSKSSSTTQGSIQIELHFRSTKDSSCFTVVLNNLRVFLIFDWLLLVHDFLHTPSDIKKPAKVTPFRHRNSSSESAVIPKTVKSGVVTKRSSLPVSTERHLEVKVNVTGTEFVVVEDVSCFDTNAIILKGTTVLTYKPRFVDRPFSGSLFGIEVFSCRLGNEHDTALSIVDPVQIHVELVGNSSYQNSSGLMDAFNSEDFPPILEIQLQALDIRLSYNDVQLFLAIAKSIPEQANAAVPDVAALEASSVHSYLPGASRGGEEVREGTRHTLDPVLELQLARLQELGFSTDDCRKALLVCQGQLKKAASWLFKNAEPRTSLSLASNSQQSQGAAPAWLISGVEMKAESVCICFIDDCMDCDVPLAELTFSRLNFLQHVRTSPEGYAHFTLSGDYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKQRLDVNITSVLIDQYISTKESWMADYCKQDKEVDPTPSEDWMGSSVDPPCFGQKMKAPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTLLDDAHNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFRYAAPDKNSSSSTIGSPSSRTNIIHPQVYFSSLPPVRVVFAVTMEGSARKVITVRSALIVKNRLETPMELRLDSPSAPDKPVVLPAIMPGDSFAVPLHLTSWRLQARPKGLGVFFCKAPIHWTNVVKTAEVSSSKRECHSMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDFYVKGMPINGTLKPGKEVALHTADTSQNIELGVSLENFPLCKELLIPPGTQNYMVRMRLYDTNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRALRVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMDVPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPTPFRIDNFSKVPVVFTQHGVAEPRLRTEVKPMTSLDYAWDEPTLPPFITLTVKGAGSSEISCNMNDFQDNQQLYYENFIYIAATYTFSGSSLQEGTGRPVTSNKAVTCAELVLDVSPKTQRVILKKKEPGKRSQLWRMTGTGMLAHEGSSVPHNPSEPSAARSAEGSAILDIAGLAAVTDNRYEPLMLRKPDRRRSTTQTWSFREGKLTCGLHGLVVQAKGGLSGLFDGAEVVLGPDTSMQLLGPVPPEQQFINQKMRPGSGMLSIRVVPDGPTRALQITDFSQRKSDRSSYEVDELPVTERELQKLKNPDTEQELEVLVKLEGGIGLSLINKVPEELVFASLTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSTLTNIYKHLMVTAQRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDENLHEKTAEQGGTPIRYYFENLKISIPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKDFIINDILKHFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAKSLSAMILEPKKRKSVTASTFSLLFAMK", "length": 4115, "header": "tr|E1BIF6-1|A0ABI0NRI1_BOVIN Computationally mapped isoform of Vacuolar protein sorting 13 homolog D OS=Bos taurus OX=9913 GN=VPS13D PE=3 SV=4 CANONICAL=A0ABI0NRI1-1" }, "locus": { "chromosome": "16", "start_pos": 41473842, "end_pos": 41276305, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046426.6", "url": "https://www.ensembl.org/id/ENSBTAT00000046426.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043730.5", "url": "https://www.ensembl.org/id/ENSBTAP00000043730.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1761, "start_aa": "Thr", "end_pos": 1761, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1761", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1767, "start_aa": "Thr", "end_pos": 1767, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1767", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2833, "start_aa": "Thr", "end_pos": 2833, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2833", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3788, "start_aa": "Thr", "end_pos": 3788, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3788", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRI1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1" } ], "pmid": "" }, { "name": "protein retention in Golgi apparatus", "id": "GO:0045053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045053", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRI1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRI1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRI1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1025, "end_pos": 1027, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1060, 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"https://www.uniprot.org/uniprotkb/A0ABI0NQK5#function" }, { "database": "UniProtKB", "id": "A0AAF6YYX1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YYX1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQK5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF227", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5", "locus": { "chromosome": "18", "start_pos": 52167641, "end_pos": 52155515, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000027431", "url": "https://www.ensembl.org/id/ENSBTAG00000027431" } ] } } ], "crossref": [ { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF68", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF68", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SC72", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SC72-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YYX1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YYX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YYX1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YYX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQK5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQK5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAAVYTGNVRRTQSFCPTASFSSPVLNPEGRERKDFLPPQSIAAVMPSQDSDFPQKEHEKMTEFQEAVTFKDVAVVFTEEELGLLDSAQRKLYQDVMVENFRNLVSVGHVPFKADMVSQLETEEKLWTMERETQRNGHSSEIHSAVTSGSKIPNEMETLGKVMFKYLSCEELSCWQIWKHTTNDLTLQRKSSWFLHGDSLQVSEDENHIMNHKGDHFGCLENQEFLIPTAQASCGSRCLSESENPSRGKQMSVKNHLHVCEGFTKNSPLSDPGKTDAKQTPCKGERPHPCRVCGEGFSHGAVLPVHQVDPGEKCSHLQTHQRIHPGGTVNKCPKSGDGFHQNSFHPHHSNPTGEKSYRCDSCGKAFGSSTGLIIHYRTHTGEKPYRCEACGKCFSQSSNFQCHQRVHTEEKPYKCEECGKGFGWSVNLRVHQRVHRGEKPYKCEECGKGFTQAAHYHIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTGEKPYRCEACGKGFTRNTDLHIHFRVHTGEKPYTCKECGKGFSQASNLQVHQNVHTGEKRFKCETCGKGFSQSSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQVIHTGEKPYTCEACGKGFSWRSNLHAHQRVHSGEKPYKCEACDKSFSQAIDFRVHQRVHTGEKPYKCGVCGKGFSQSSGLQSHQRVHTGEKPYKCDVCGKGFRYSSQFIYHQRGHTGEKPYKCEECGKGFGRSLNLRHHQRVHTGEKPHKCEECGKAFSLPSNLRVHLSVHTREKLFKCEDCGKGFSQSSRLQAHQRVHTGEKPYKCNICVLIVNGCWRISRKHSPGETKHGIFV", "length": 836, "header": "tr|A0ABI0NQK5-1|A0ABI0NQK5_BOVIN Isoform 1 of Zinc finger protein 227 OS=Bos taurus OX=9913 GN=ZNF227 PE=3 SV=1 CANONICAL=A0ABI0NQK5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SC72-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5/entry#A0AAA9SC72-1", "sequence": { "sequence": "MVPALEDRGHVPFKADMVSQLETEEKLWTMERETQRNGHSSEIHSAVTSGSKIPNEMETLGKVMFKYLSCEELSCWQIWKHTTNDLTLQRKSSWFLHGDSLQVSEDENHIMNHKGDHFGCLENQEFLIPTAQASCGSRCLSESENPSRGKQMSVKNHLHVCEGFTKNSPLSDPGKTDAKQTPCKGERPHPCRVCGEGFSHGAVLPVHQVDPGEKCSHLQTHQRIHPGGTVNKCPKSGDGFHQNSFHPHHSNPTGEKSYRCDSCGKAFGSSTGLIIHYRTHTGEKPYRCEACGKCFSQSSNFQCHQRVHTEEKPYKCEECGKGFGWSVNLRVHQRVHRGEKPYKCEECGKGFTQAAHYHIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTGEKPYRCEACGKGFTRNTDLHIHFRVHTGEKPYTCKECGKGFSQASNLQVHQNVHTGEKRFKCETCGKGFSQSSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQVIHTGEKPYTCEACGKGFSWRSNLHAHQRVHSGEKPYKCEACDKSFSQAIDFRVHQRVHTGEKPYKCGVCGKGFSQSSGLQSHQRVHTGEKPYKCDVCGKGFRYSSQFIYHQRGHTGEKPYKCEECGKGFGRSLNLRHHQRVHTGEKPHKCEECGKAFSLPSNLRVHLSVHTREKLFKCEDCGKGFSQSSRLQAHQRVHTGEKPYKCNICGKDFSHRSRLTYHQKVHTGKNL", "length": 733, "header": "tr|A0AAA9SC72-1|A0ABI0NQK5_BOVIN Computationally mapped isoform of Zinc finger protein 227 OS=Bos taurus OX=9913 GN=ZNF227 PE=3 SV=1 CANONICAL=A0ABI0NQK5-1" }, "locus": { "chromosome": "18", "start_pos": 52166952, "end_pos": 52159938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135802.2", "url": "https://www.ensembl.org/id/ENSBTAT00000135802.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081118.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081118.1" } ] } }, { "isoform_ac": "A0AAF6YYX1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5/entry#A0AAF6YYX1-1", "sequence": { "sequence": "MSAAVYTGNVRRTQSFCPTASFSSPVLNPEGRERKDFLPPQSIAAVMPSQDSDFPQKEHEKMTEFQEAVTFKDVAVVFTEEELGLLDSAQRKLYQDVMVENFRNLVSVGHVPFKADMVSQLETEEKLWTMERETQRNGHSSEIHSAVTSGSKIPNEMETLGKVMFKYLSCEELSCWQIWKHTTNDLTLQRKSSWFLHGDSLQVSEDENHIMNHKGDHFGCLENQEFLIPTAQASCGSRCLSESENPSRGKQMSVKNHLHVCEGFTKNSPLSDPGKTDAKQTPCKGERPHPCRVCGEGFSHGAVLPVHQVDPGEKCSHLQTHQRIHPGGTVNKCPKSGDGFHQNSFHPHHSNPTGEKSYRCDSCGKAFGSSTGLIIHYRTHTGEKPYRCEACGKCFSQSSNFQCHQRVHTEEKPYKCEECGKGFGWSVNLRVHQRVHRGEKPYKCEECGKGFTQAAHYHIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTGEKPYRCEACGKGFTRNTDLHIHFRVHTGEKPYTCKECGKGFSQASNLQVHQNVHTGEKRFKCETCGKGFSQSSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQVIHTGEKPYTCEACGKGFSWRSNLHAHQRVHSGEKPYKCEACDKSFSQAIDFRVHQRVHTGEKPYKCGVCGKGFSQSSGLQSHQRVHTGEKPYKCDVCGKGFRYSSQFIYHQRGHTGEKPYKCEECGKGFGRSLNLRHHQRVHTGEKPHKCEECGKAFSLPSNLRVHLSVHTREKLFKCEDCGKGFSQSSRLQAHQRVHTGEKPYKCNICGKDFSHRSRLTYHQKVHTGKNL", "length": 833, "header": "tr|A0AAF6YYX1-1|A0ABI0NQK5_BOVIN Computationally mapped isoform of Zinc finger protein 227 OS=Bos taurus OX=9913 GN=ZNF227 PE=3 SV=1 CANONICAL=A0ABI0NQK5-1" }, "locus": { "chromosome": "18", "start_pos": 52166952, "end_pos": 52155549, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017798.8", "url": "https://www.ensembl.org/id/ENSBTAT00000017798.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017798.6", "url": "https://www.ensembl.org/id/ENSBTAP00000017798.6" } ] } }, { "isoform_ac": "A0ABI0NQK5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5/entry#A0ABI0NQK5-1", "sequence": { "sequence": "MSAAVYTGNVRRTQSFCPTASFSSPVLNPEGRERKDFLPPQSIAAVMPSQDSDFPQKEHEKMTEFQEAVTFKDVAVVFTEEELGLLDSAQRKLYQDVMVENFRNLVSVGHVPFKADMVSQLETEEKLWTMERETQRNGHSSEIHSAVTSGSKIPNEMETLGKVMFKYLSCEELSCWQIWKHTTNDLTLQRKSSWFLHGDSLQVSEDENHIMNHKGDHFGCLENQEFLIPTAQASCGSRCLSESENPSRGKQMSVKNHLHVCEGFTKNSPLSDPGKTDAKQTPCKGERPHPCRVCGEGFSHGAVLPVHQVDPGEKCSHLQTHQRIHPGGTVNKCPKSGDGFHQNSFHPHHSNPTGEKSYRCDSCGKAFGSSTGLIIHYRTHTGEKPYRCEACGKCFSQSSNFQCHQRVHTEEKPYKCEECGKGFGWSVNLRVHQRVHRGEKPYKCEECGKGFTQAAHYHIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTGEKPYRCEACGKGFTRNTDLHIHFRVHTGEKPYTCKECGKGFSQASNLQVHQNVHTGEKRFKCETCGKGFSQSSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQVIHTGEKPYTCEACGKGFSWRSNLHAHQRVHSGEKPYKCEACDKSFSQAIDFRVHQRVHTGEKPYKCGVCGKGFSQSSGLQSHQRVHTGEKPYKCDVCGKGFRYSSQFIYHQRGHTGEKPYKCEECGKGFGRSLNLRHHQRVHTGEKPHKCEECGKAFSLPSNLRVHLSVHTREKLFKCEDCGKGFSQSSRLQAHQRVHTGEKPYKCNICVLIVNGCWRISRKHSPGETKHGIFV", "length": 836, "header": "tr|A0ABI0NQK5-1|A0ABI0NQK5_BOVIN Isoform 1 of Zinc finger protein 227 OS=Bos taurus OX=9913 GN=ZNF227 PE=3 SV=1 CANONICAL=A0ABI0NQK5-1" }, "locus": { "chromosome": "18", "start_pos": 52167878, "end_pos": 52155549, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147223.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147223.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104519.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104519.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQK5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQK5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQK5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5" } ], "pmid": "" }, { "name": "nuclear lumen", "id": "GO:0031981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQK5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQK5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQK5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NQK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 358, "end_pos": 385, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NQK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQK5" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 69, "end_pos": 140, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQ95-1", "uniprot_ac": "A0ABI0NQ95", "uniprot_id": "A0ABI0NQ95_BOVIN", "mass": { "chemical_mass": 81643.0, "monoisotopic_mass": 81643.0 }, "refseq": {}, "gene_names": [ { "name": "TRDN", "type": "recommended", "evidence": [ { "id": "A0ABI0NQ95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95" } ] } ], "protein_names": [ { "name": "Triadin", "type": "recommended", "evidence": [ { "id": "A0ABI0NQ95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Contributes to the regulation of lumenal Ca2+ release via the sarcoplasmic reticulum calcium release channels RYR1 and RYR2, a key step in triggering skeletal and heart muscle contraction. Required for normal organization of the triad junction, where T-tubules and the sarcoplasmic reticulum terminal cisternae are in close contact. Required for normal skeletal muscle strength. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SPD2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPD2#function" }, { "database": "UniProtKB", "id": "ARBA00046074", "url": "https://www.uniprot.org/uniprotkb/ARBA00046074#function" }, { "database": "UniProtKB", "id": "A0AAA9SR28", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SR28#function" }, { "database": "UniProtKB", "id": "F1MDY1", "url": "https://www.uniprot.org/uniprotkb/F1MDY1#function" }, { "database": "UniProtKB", "id": "A0ABI0NLI2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLI2#function" }, { "database": "UniProtKB", "id": "A0ABI0NQ95", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95#function" }, { "database": "UniProtKB", "id": "A0ABI0NSB1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSB1#function" }, { "database": "UniProtKB", "id": "A0ABI0P566", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P566#function" }, { "database": "UniProtKB", "id": "A0ABI0P642", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P642#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ95", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TRDN", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95", "locus": { "chromosome": "9", "start_pos": 28113791, "end_pos": 27620644, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038849", "url": "https://www.ensembl.org/id/ENSBTAG00000038849" } ] } } ], "crossref": [ { "id": "ENSBTAG00000038849", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038849", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010798", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010798", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MDY1", "url": "https://www.orthodb.org/?gene=F1MDY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14106:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14106:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05279", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05279", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SPD2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPD2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SR28", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SR28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SR28-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SR28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLI2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLI2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ95", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ95-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSB1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSB1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P566", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P566", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P566-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P566-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P642", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P642", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P642-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P642-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MDY1", "url": "https://www.uniprot.org/uniprotkb/F1MDY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MDY1-1", "url": "https://www.uniprot.org/uniprotkb/F1MDY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEITAEGNASTTTTVIDSKNGSVPKASGKVLKRTVTEDLVTTFSSPAAWLLVIALIITWSAVAVVMFDLVDYKNLSASSISKIGSDPLKLVHDAVEETTDWVYGFFSLLSDIISSEGDEEDDDDGEEDTDKGEIEEPPLKKKEIHKEKTEKLEKPEKKIQTKVTHKEKDKVKEKEKPEKKATHKEKIQKKEKPETKTVAKEEKKAKTREKIEEKIKKEVKGVKQEKVKQTATKVKEVQKTSPKPKKDEKDAAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTLASPTLEEKEEEKKKAEKNVTSETKKKDKEDVKMKTEKETAMDVKRKEPSKAPETKQGTIKVAAQAPTKKEEKKEDSKKTKTPTEAELPKGKKQEKKEQHVEPAKSPKKEQSAPSEKHIKAKTERTKEEVGSASSKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSVPKDKDPIKEKEVKVPASLKEKEPEIKKDEKMPKAGKEVKPKSPQPQVKKQEKPESQVKKEAKPASSEKAQIHKQDTVKPEKAISHGKPDEKVVKHVKATTIEKTVKPKPTKKAEHQGKESPSIKTDKPKPTPKETQEVTESAKKKIEKSEKESKEKAEMRHLKEEKVPTRKESLQLHNVTKVEKPARISKDSEDVPTSKKAKEEAEEVSSTKKQKTPISFFQCVYLDGYNGYGFQFPVTPVHHPGESSGQPNSPGQKHQRQ", "length": 727, "header": "tr|A0ABI0NQ95-1|A0ABI0NQ95_BOVIN Isoform 1 of Triadin OS=Bos taurus OX=9913 GN=TRDN PE=4 SV=1 CANONICAL=A0ABI0NQ95-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SPD2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95/entry#A0AAA9SPD2-1", "sequence": { "sequence": "MTEITAEGNASTTTTVIDSKNGSVPKASGKVLKRTVTEDLVTTFSSPAAWLLVIALIITWSAVAVVMFDLVDYKNLSASSISKIGSDPLKLVHDAVEETTDWVYGFFSLLSDIISSEGDEEDDDDGEEDTDKGEIEEPPLKKKEIHKEKTEKLEKPEKKIQTKVTHKEKDKVKEKEKPEKKATHKEKIQKKEKPETKTVAKEEKKAKTREKIEEKIKKEVKGVKQEKVKQTATKVKEVQKTSPKPKKDEKDAAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTLASPTLEEKEEEKKKAEKNVTSETKKKDKEDVKMKTEKETAMDVKRKEPSKAPETKQGTIKVAAQAPTKKEEKKEDSKKTKTPTEELPKGKKQEKKEQHVEPAKSPKKEQSAPSEKHIKAKTERTKEEVGSASSKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSVPKDKDPIKEKEVKVPASLKEKEPEIKKDEKMPKAGKEVKPKSPQPQVKKQEKPESQVKKEAKPASSEKAQIHKQDTVKPEKAISHGKPDEKVVKHVKATTIEKTVKPKPTKKAEHQGKESPSIKTDKPKPTPKETQEVTESAKKKIEKSEKESKEKAEMRHLKEEKEKAEMRHLKEEKEKAEMRHLKGEKEKAEMRH", "length": 662, "header": "tr|A0AAA9SPD2-1|A0ABI0NQ95_BOVIN Computationally mapped isoform of Triadin OS=Bos taurus OX=9913 GN=TRDN PE=4 SV=2 CANONICAL=A0ABI0NQ95-1" }, "locus": { "chromosome": "9", "start_pos": 28085106, "end_pos": 27701385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102731.2", "url": "https://www.ensembl.org/id/ENSBTAT00000102731.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085854.2", "url": "https://www.ensembl.org/id/ENSBTAP00000085854.2" } ] } }, { "isoform_ac": "A0AAA9SR28-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95/entry#A0AAA9SR28-1", "sequence": { "sequence": "MTEITAEGNASTTTTVIDSKNGSVPKASGKVLKRTVTEDLVTTFSSPAAWLLVIALIITWSAVAVVMFDLVDYKNLSASSISKIGSDPLKLVHDAVEETTDWVYGFFSLLSDIISSEGDEEDDDDGEEDTDKGEIEEPPLKKKEIHKEKTEKLEKPEKKIQTKDWSANLYTTRTMKVTQLKPIYIWT", "length": 187, "header": "tr|A0AAA9SR28-1|A0ABI0NQ95_BOVIN Computationally mapped isoform of Triadin OS=Bos taurus OX=9913 GN=TRDN PE=4 SV=2 CANONICAL=A0ABI0NQ95-1" }, "locus": { "chromosome": "9", "start_pos": 27820053, "end_pos": 27701385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120544.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120544.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088801.2", "url": "https://www.ensembl.org/id/ENSBTAP00000088801.2" } ] } }, { "isoform_ac": "A0ABI0NLI2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95/entry#A0ABI0NLI2-1", "sequence": { "sequence": "MTEITAEGNASTTTTVIDSKNGSVPKASGKVLKRTVTEDLVTTFSSPAAWLLVIALIITWSAVAVVMFDLVDYKNLSASSISKIGSDPLKLVHDAVEETTDWVYGFFSLLSDIISSEGDEEDDDDGEEDTDKGEIEEPPLKKKEIHKEKTEKLEKPEKKIQTKVTHKEKDKVKEKEKPEKKATHKEKIQKKEKPETKTVAKEEKKAKTREKIEEKIKKEVKGVKQEKVKQTATKVKEVQKTSPKPKKDEKDAAAVSKHEQKGQSPAIPPPLPTEQASRPTLASPTLEEKEEEKKKAEKNVTSETKKKDKEDVKMKTEKETAMDVKRKEPSKAPETKQGTIKVAAQAPTKKEEKKEDSKKTKTPTEELPKGKKQEKKEQHVEPAKSPKKEQSAPSEKHIKAKTERTKEEVGSASSKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSVPKDKDPIKEKEVKVPASLKEKEPEIKKDEKMPKAGKEVKPKSPQPQVKKQEKPESQVKKEAKPASSEKAQIHKQDTVKPEKAISHGKPDEKVVKHVKATTIEKTVKPKPTKKAEHQGKESPSIKTDKPKPTPKETQEVTESAKKKIEKSEKESKEKAEMRHLKEEKEKAEMRHLKEEKEKAEMRHLKGEKEKAEMRHLKEEKGSSFIHLIRTDSFYLYRKSRNETS", "length": 671, "header": "tr|A0ABI0NLI2-1|A0ABI0NQ95_BOVIN Computationally mapped isoform of Triadin OS=Bos taurus OX=9913 GN=TRDN PE=4 SV=1 CANONICAL=A0ABI0NQ95-1" }, "locus": { "chromosome": "9", "start_pos": 28084632, "end_pos": 27701385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140681.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140681.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106000.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106000.1" } ] } }, { "isoform_ac": "A0ABI0NQ95-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95/entry#A0ABI0NQ95-1", "sequence": { "sequence": "MTEITAEGNASTTTTVIDSKNGSVPKASGKVLKRTVTEDLVTTFSSPAAWLLVIALIITWSAVAVVMFDLVDYKNLSASSISKIGSDPLKLVHDAVEETTDWVYGFFSLLSDIISSEGDEEDDDDGEEDTDKGEIEEPPLKKKEIHKEKTEKLEKPEKKIQTKVTHKEKDKVKEKEKPEKKATHKEKIQKKEKPETKTVAKEEKKAKTREKIEEKIKKEVKGVKQEKVKQTATKVKEVQKTSPKPKKDEKDAAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTLASPTLEEKEEEKKKAEKNVTSETKKKDKEDVKMKTEKETAMDVKRKEPSKAPETKQGTIKVAAQAPTKKEEKKEDSKKTKTPTEAELPKGKKQEKKEQHVEPAKSPKKEQSAPSEKHIKAKTERTKEEVGSASSKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSVPKDKDPIKEKEVKVPASLKEKEPEIKKDEKMPKAGKEVKPKSPQPQVKKQEKPESQVKKEAKPASSEKAQIHKQDTVKPEKAISHGKPDEKVVKHVKATTIEKTVKPKPTKKAEHQGKESPSIKTDKPKPTPKETQEVTESAKKKIEKSEKESKEKAEMRHLKEEKVPTRKESLQLHNVTKVEKPARISKDSEDVPTSKKAKEEAEEVSSTKKQKTPISFFQCVYLDGYNGYGFQFPVTPVHHPGESSGQPNSPGQKHQRQ", "length": 727, "header": "tr|A0ABI0NQ95-1|A0ABI0NQ95_BOVIN Isoform 1 of Triadin OS=Bos taurus OX=9913 GN=TRDN PE=4 SV=1 CANONICAL=A0ABI0NQ95-1" }, "locus": { "chromosome": "9", "start_pos": 28113788, "end_pos": 27701385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148843.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148843.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105444.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105444.1" } ] } }, { "isoform_ac": "A0ABI0NSB1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95/entry#A0ABI0NSB1-1", "sequence": { "sequence": "MTEITAEGNASTTTTVIDSKNGSVPKASGKVLKRTVTEDLVTTFSSPAAWLLVIALIITWSAVAVVMFDLVDYKNLSASSISKIGSDPLKLVHDAVEETTDWVYGFFSLLSDIISSEGDEEDDDDGEEDTDKGEIEEPPLKKKEIHKEKTEKLEKPEKKIQTKVTHKEKDKVKEKEKPEKKATHKEKIQKKEKPETKTVAKEEKKAKTREKIEEKIKKEVKGVKQEKVKQTATKVKEVQKTSPKPKKDEKDAAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTLASPTLEEKEEEKKKAEKNVTSETKKKDKEDVKMKTEKETAMDVKRKEPSKAPETKQGTIKVAAQAPTKKEEKKEDSKKTKTPTEELPKGKKQEKKEQHVEPAKSPKKEQSAPSEKHIKAKTERTKEEVGSASSKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSVPKDKDPIKEKEVKVPASLKEKEPEIKKDEKMPKAGKEVKPKSPQPQVKKQEKPESQVKKEAKPASSEKAQIHKQDTVKPEKAISHGKPDEKVVKHVKATTIEKTVKPKPTKKAEHQGKESPSIKTDKPKPTPKETQEVTESAKKKIEKSEKESKEKAEMRHLKEEKEKAEMRHLKEEKEKAEMRHLKGEKEKAEMRHLKGEKEKAEMR", "length": 673, "header": "tr|A0ABI0NSB1-1|A0ABI0NSB1_BOVIN Computationally mapped isoform of Triadin OS=Bos taurus OX=9913 GN=TRDN PE=4 SV=1 CANONICAL=A0ABI0NQ95-1" }, "locus": { "chromosome": "9", "start_pos": 28085103, "end_pos": 27701385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142857.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142857.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105886.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105886.1" } ] } }, { "isoform_ac": "A0ABI0P566-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95/entry#A0ABI0P566-1", "sequence": { "sequence": "MTEITAEGNASTTTTVIDSKNGSVPKASGKVLKRTVTEDLVTTFSSPAAWLLVIALIITWSAVAVVMFDLVDYKNLSASSISKIGSDPLKLVHDAVEETTDWVYGFFSLLSDIISSEGDEEDDDDGEEDTDKGEIEEPPLKKKEIHKEKTEKLEKPEKKIQTKVTHKEKDKVKEKEKPEKKATHKEKIQKKEKPETKTVAKEEKKAKTREKIEEKIKKEVKGVKQEKVKQTATKVKEVQKTSPKPKKDEKDAAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTLASPTLEEKEEEKKKAEKNVTSETKKKDKEDVKMKTEKETAMDVKRKEPSKAPETKQGTIKVAAQAPTKKEEKKEDSKKTKTPTEELPKGKKQEKKEQHVEPAKSPKKEQSAPSEKHIKAKTERTKEEVGSASSKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSVPKDKDPIKEKEVKVPASLKEKEPEIKKDEKMPKAGKEVKPKSPQPQVKKQEKPESQVKKEAKPASSEKAQIHKQDTVKPEKAISHGKPDEKVVKHVKATTIEKTVKPKPTKKAEHQGKESPSIKTDKPKPTPKETQEVTESAKKKIEKSEKESKEKAEMRHLKEEKEKAEMRHLKEEKEKAEMRHLKGEKEKAEMRHLKEEKEKAEMRHLKEEKEKAEMRHLKGEKEKAEMRHLKGQKEKAEVRHLK", "length": 712, "header": "tr|A0ABI0P566-1|A0ABI0P566_BOVIN Computationally mapped isoform of Triadin OS=Bos taurus OX=9913 GN=TRDN PE=4 SV=1 CANONICAL=A0ABI0NQ95-1" }, "locus": { "chromosome": "9", "start_pos": 28084993, "end_pos": 27701385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147594.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147594.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106279.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106279.1" } ] } }, { "isoform_ac": "A0ABI0P642-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95/entry#A0ABI0P642-1", "sequence": { "sequence": "MTEITAEGNASTTTTVIDSKNGSVPKASGKVLKRTVTEDLVTTFSSPAAWLLVIALIITWSAVAVVMFDLVDYKNLSASSISKIGSDPLKLVHDAVEETTDWVYGFFSLLSDIISSEGDEEDDDDGEEDTDKGEIEEPPLKKKEIHKEKTEKLEKPEKKIQTKVTHKEKDKVKEKEKPEKKATHKEKIQKKEKPETKTVAKEEKKAKTREKIEEKIKKEVKGVKQEKVKQTATKVKEVQKTSPKPKKDEKDAAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTLASPTLEEKEEEKKKAEKNVTSETKKKADKEDVKMKTEKETAMDVKRKEPSKAPETKQGTIKVAAQAPTKKEEKKEDSKKTKTPTEAELPKGKKQEKKEQHVEPAKSPKKEQSAPSEKHIKAKTERTKEEVGSASSKKAVPGKKEEKTTKTVEQGKKK", "length": 458, "header": "tr|A0ABI0P642-1|A0ABI0P642_BOVIN Computationally mapped isoform of Triadin OS=Bos taurus OX=9913 GN=TRDN PE=4 SV=1 CANONICAL=A0ABI0NQ95-1" }, "locus": { "chromosome": "9", "start_pos": 28008823, "end_pos": 27701385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136099.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136099.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106577.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106577.1" } ] } }, { "isoform_ac": "F1MDY1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95/entry#F1MDY1-1", "sequence": { "sequence": "MTEITAEGNASTTTTVIDSKNGSVPKASGKVLKRTVTEDLVTTFSSPAAWLLVIALIITWSAVAVVMFDLVDYKNLSASSISKIGSDPLKLVHDAVEETTDWVYGFFSLLSDIISSEGDEEDDDDGEEDTDKGEIEEPPLKKKEIHKEKTEKLEKPEKKIQTKVTHKEKDKVKEKEKPEKKATHKEKIQKKEKPETKTVAKEEKKAKTREKIEEKIKKEVKGVKQEKVKQTATKVKEVQKTSPKPKKDEKDAAAVSKHEQKGLPGPGMRIPCYYCQYIQEQIDSWTDLRALPATTHLTGLLIDFNSQ", "length": 307, "header": "tr|F1MDY1-1|A0ABI0NQ95_BOVIN Computationally mapped isoform of Triadin OS=Bos taurus OX=9913 GN=TRDN PE=4 SV=5 CANONICAL=A0ABI0NQ95-1" }, "locus": { "chromosome": "9", "start_pos": 27847856, "end_pos": 27701385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056240.5", "url": "https://www.ensembl.org/id/ENSBTAT00000056240.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048415.5", "url": "https://www.ensembl.org/id/ENSBTAP00000048415.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ95", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ95" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "sarcoplasmic reticulum membrane", "id": "GO:0033017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033017", "evidence": [ { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NNN1-1", "uniprot_ac": "A0ABI0NNN1", "uniprot_id": "A0ABI0NNN1_BOVIN", "mass": { "chemical_mass": 65165.0, "monoisotopic_mass": 65165.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0ABI0NNN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNN1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000034090", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000034090", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23232:SF158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23232:SF158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NNN1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNN1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWB6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWB6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXK4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXK4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MT59", "url": "https://www.uniprot.org/uniprotkb/F1MT59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MT59-1", "url": "https://www.uniprot.org/uniprotkb/F1MT59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLKVFSQHVDVSLRRNIPTEDEEQEEEEEEMAASQERLIFQDVAIDFTQEEWECLDLDQRELYRDVMLENYRNLASLAGLVVSKLDLVTFLEQMKNPWDVRRLEPPAIYTAVSSHNTRGLMSKNPRLENLIQKANLGIYERAHLGNEHLMKDQEYTGICERSRRCLYGHKETEIVSHKADITAKRNEQCESTCGKHPFPLSTSAEKCISSSKGLHHFLKRTRSLKGNVENLESHPVSTANTHSNHSEHGLRLHIHSSTSENQKFKNDGENSQYNQFEGSVSKGSLFFHQQTVSLCSKMCHVDNNGRELIPPSLFNTHHDTVNTEQLLTCNNMSQALSKSSTPNNYKHIYDGVRNHSCNETGYKTEQDSNPMKHQGPQSSDKDSKNSTCRNILYQISGLPLNESTHTGEKTYNCEYGDVSNQSSNLTQQQSIQNPQTSYKCKKCEKTFTNSSSLSRQRKIHSGWKPFKCTECGNTSNQNSKLSQDRQIHTGKKPYECKECGKAFMSCSHLSRHQRIHTGEKPYKCTKCGKAFNQNSNLTQHQRIHTEQKPYKGKEGGKAIFRCSHFSLHQ", "length": 570, "header": "tr|A0ABI0NNN1-1|A0ABI0NNN1_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NNN1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NNN1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1/entry#A0ABI0NNN1-1", "sequence": { "sequence": "MPLKVFSQHVDVSLRRNIPTEDEEQEEEEEEMAASQERLIFQDVAIDFTQEEWECLDLDQRELYRDVMLENYRNLASLAGLVVSKLDLVTFLEQMKNPWDVRRLEPPAIYTAVSSHNTRGLMSKNPRLENLIQKANLGIYERAHLGNEHLMKDQEYTGICERSRRCLYGHKETEIVSHKADITAKRNEQCESTCGKHPFPLSTSAEKCISSSKGLHHFLKRTRSLKGNVENLESHPVSTANTHSNHSEHGLRLHIHSSTSENQKFKNDGENSQYNQFEGSVSKGSLFFHQQTVSLCSKMCHVDNNGRELIPPSLFNTHHDTVNTEQLLTCNNMSQALSKSSTPNNYKHIYDGVRNHSCNETGYKTEQDSNPMKHQGPQSSDKDSKNSTCRNILYQISGLPLNESTHTGEKTYNCEYGDVSNQSSNLTQQQSIQNPQTSYKCKKCEKTFTNSSSLSRQRKIHSGWKPFKCTECGNTSNQNSKLSQDRQIHTGKKPYECKECGKAFMSCSHLSRHQRIHTGEKPYKCTKCGKAFNQNSNLTQHQRIHTEQKPYKGKEGGKAIFRCSHFSLHQ", "length": 570, "header": "tr|A0ABI0NNN1-1|A0ABI0NNN1_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NNN1-1" }, "locus": { "chromosome": "18", "start_pos": 57202379, "end_pos": 57194158, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148721.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148721.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107430.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107430.1" } ] } }, { "isoform_ac": "A0ABI0NWB6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1/entry#A0ABI0NWB6-1", "sequence": { "sequence": "MPLKVFSQHADVSLRRNIPTEDTEQEEEEEEMAASQERLIFQDVAIDFTQEEWECLDLDQRELYRDVMLENYRNLASLGLVVSKLDLVTFLEQMKNPWDVRRLEPPAIYTAVSSHNTRGLMSKNPRLENLIQKANLGIYERAHLGNEHLMKDQEYTGICERSRRCLYGHKETEIVSHKADITAKRNEQCESTCGKHPFPLSTSAEKCISSSKGLHHFLKRTRSLKGNVENLESHPVSTANTHSNHSEHGLRLHIHSSTSENQKFKNDGENSQYNQFEGSVSKGSLFFHQQTVSLCSKMCHVDNNGRELIPPSLFNTHHDTVNTEQLLTCNNMSQALSKSSTPNNYKHIYDGVRNHSCNETGYKTEQDSNPMKHQGPQSSDKDSKNSTCRNILYQISGLPLNESTHTGEKTYNCEYGDVSNQSSNLTQQQSIQNPQTSYKCKKCEKTFTNSSSLSRQRKIHSGWKPFKCTECGNTSNQNSKLSQDRQIHTGKKPYECKECGKAFMSCSHLSRHQRIHTGEKPYKCTKCGKAFNQNSNLTQHQRIHTEQKPYKGKEGGKAIFRCSHFSLHQ", "length": 569, "header": "tr|A0ABI0NWB6-1|A0ABI0NWB6_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NNN1-1" }, "locus": { "chromosome": "18", "start_pos": 57214949, "end_pos": 57194158, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153433.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153433.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105228.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105228.1" } ] } }, { "isoform_ac": "A0ABI0NXK4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1/entry#A0ABI0NXK4-1", "sequence": { "sequence": "MPLKVFSQHADVSLRRNIPTEDTEQEEEEEEMAASQERLIFQDVAIDFTQEEWECLDLDQRELYRDVMLENYRNLASLAGLVVSKLDLVTFLEQMKNPWDVRRLEPPAIYTAVSSHNTRGLMSKNPRLENLIQKANLGIYERAHLGNEHLMKDQEYTGICERSRRCLYGHKETEIVSHKADITAKRNEQCESTCGKHPFPLSTSAEKCISSSKGLHHFLKRTRSLKGNVENLESHPVSTANTHSNHSEHGLRLHIHSSTSENQKFKNDGENSQYNQFEGSVSKGSLFFHQQTVSLCSKMCHVDNNGRELIPPSLFNTHHDTVNTEQLLTCNNMSQALSKSSTPNNYKHIYDGVRNHSCNETGYKTEQDSNPMKHQGPQSSDKDSKNSTCRNILYQISGLPLNESTHTGEKTYNCEYGDVSNQSSNLTQQQSIQNPQTSYKCKKCEKTFTNSSSLSRQRKIHSGWKPFKCTECGNTSNQNSKLSQDRQIHTGKKPYECKECGKAFMSCSHLSRHQRIHTGEKPYKCTKCGKAFNQNSNLTQHQRIHTEQKPYKGKEGGKAIFRCSHFSLHQ", "length": 570, "header": "tr|A0ABI0NXK4-1|A0ABI0NXK4_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NNN1-1" }, "locus": { "chromosome": "18", "start_pos": 57214949, "end_pos": 57194158, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138583.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138583.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106633.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106633.1" } ] } }, { "isoform_ac": "F1MT59-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1/entry#F1MT59-1", "sequence": { "sequence": "MAASQERLIFQDVAIDFTQEEWECLDLDQRELYRDVMLENYRNLASLAGLVVSKLDLVTFLEQMKNPWDVRRLEPPAIYTAVSSHNTRGLMSKNPRLENLIQKANLGIYERAHLGNEHLMKDQEYTGICERSRRCLY", "length": 137, "header": "tr|F1MT59-1|A0ABI0NNN1_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=5 CANONICAL=A0ABI0NNN1-1" }, "locus": { "chromosome": "18", "start_pos": 57207246, "end_pos": 57195364, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053046.5", "url": "https://www.ensembl.org/id/ENSBTAT00000053046.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048848.5", "url": "https://www.ensembl.org/id/ENSBTAP00000048848.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNN1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNN1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNN1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNN1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NNN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 439, "end_pos": 466, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NNN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNN1" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 111, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 245, "end_pos": 247 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 355, "end_pos": 357 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 386, "end_pos": 388 }, { "start_pos": 402, "end_pos": 404 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 474, "end_pos": 476 }, { "start_pos": 537, "end_pos": 539 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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"uniprot_ac": "A0ABI0NSH2", "uniprot_id": "A0ABI0NSH2_BOVIN", "mass": { "chemical_mass": 30141.0, "monoisotopic_mass": 30141.0 }, "refseq": {}, "gene_names": [ { "name": "RASSF3", "type": "recommended", "evidence": [ { "id": "A0ABI0NSH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH2" } ] } ], "protein_names": [ { "name": "Ras association domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0ABI0NSH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSH2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RASSF3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH2", "locus": { "chromosome": "5", "start_pos": 49101058, "end_pos": 49190907, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000064309", "url": "https://www.ensembl.org/id/ENSBTAG00000064309" } ] } } ], "crossref": [ { "id": "536808", "url": "https://www.ncbi.nlm.nih.gov/gene/536808", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:536808", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536808", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YCRDLVH", "url": "https://omabrowser.org/oma/group/YCRDLVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR22738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22738:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22738:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SY09", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY09-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5X8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5X8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5X8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGD2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGD2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSH2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSH2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTAIYKLSGKINFRVKKTHIPEGKYICHSYCQDLVHLDYPQNGKLPSGMPICEVRHSSQNNPQDVEKEKETHNYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPSQTAGKPAPSSNSCMNTLHISSTNTVGEVIEALLKKFLVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKERYAAYRHKLEEALSQAWKPG", "length": 262, "header": "tr|A0ABI0NSH2-1|A0ABI0NSH2_BOVIN Isoform 1 of Ras association domain-containing protein 3 OS=Bos taurus OX=9913 GN=RASSF3 PE=4 SV=1 CANONICAL=A0ABI0NSH2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SY09-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH2/entry#A0AAA9SY09-1", "sequence": { "sequence": "MSSGYSSLEEDSEDFFFTARTSFFRRAPQGKLRTGQQDVEKEKETHNYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPSQTAGKPAPSSNSCMNTLHISSTNTVGEVIEALLKKFLVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKERYAAYRHKLEEALSQAWKPGSSYPKLVTQHPAAWASSVRDSASLFS", "length": 261, "header": "tr|A0AAA9SY09-1|A0ABI0NSH2_BOVIN Computationally mapped isoform of Ras association domain-containing protein 3 OS=Bos taurus OX=9913 GN=RASSF3 PE=4 SV=1 CANONICAL=A0ABI0NSH2-1" }, "locus": { "chromosome": "5", "start_pos": 49190776, "end_pos": 49117054, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089402.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089402.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091357.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091357.1" } ] } }, { "isoform_ac": "A0AAA9T5X8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH2/entry#A0AAA9T5X8-1", "sequence": { "sequence": "MSSGYSSLEEDSEDFFFTARTSFFRRAPQGKLRTGQQDVEKEKETHNYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPSQTAGKPAPSSNSCMNTLHISSTNTVGEVIEALLKKFLVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKERYAAYRHKLEEALSQAWKPG", "length": 235, "header": "tr|A0AAA9T5X8-1|A0ABI0NSH2_BOVIN Computationally mapped isoform of Ras association domain-containing protein 3 OS=Bos taurus OX=9913 GN=RASSF3 PE=4 SV=1 CANONICAL=A0ABI0NSH2-1" }, "locus": { "chromosome": "5", "start_pos": 49190776, "end_pos": 49117266, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094388.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094388.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093257.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093257.1" } ] } }, { "isoform_ac": "A0AAA9TGD2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH2/entry#A0AAA9TGD2-1", "sequence": { "sequence": "MSSGYSSLEEDSEDFFFTARTSFFRRAPQGKLRTGQQDVEKEKETHNYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPSQTAGKPAPSSNSCMNTLHISSTNTVGEVIEALLKKFLVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKERYAAYRHKLEEALSQAWKPGT", "length": 236, "header": "tr|A0AAA9TGD2-1|A0ABI0NSH2_BOVIN Computationally mapped isoform of Ras association domain-containing protein 3 OS=Bos taurus OX=9913 GN=RASSF3 PE=4 SV=1 CANONICAL=A0ABI0NSH2-1" }, "locus": { "chromosome": "5", "start_pos": 49190776, "end_pos": 49101140, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133990.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133990.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097620.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097620.1" } ] } }, { "isoform_ac": "A0ABI0NSH2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH2/entry#A0ABI0NSH2-1", "sequence": { "sequence": "MGTAIYKLSGKINFRVKKTHIPEGKYICHSYCQDLVHLDYPQNGKLPSGMPICEVRHSSQNNPQDVEKEKETHNYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPSQTAGKPAPSSNSCMNTLHISSTNTVGEVIEALLKKFLVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKERYAAYRHKLEEALSQAWKPG", "length": 262, "header": "tr|A0ABI0NSH2-1|A0ABI0NSH2_BOVIN Isoform 1 of Ras association domain-containing protein 3 OS=Bos taurus OX=9913 GN=RASSF3 PE=4 SV=1 CANONICAL=A0ABI0NSH2-1" }, "locus": { "chromosome": "5", "start_pos": 49258333, "end_pos": 49117266, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149140.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149140.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105874.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105874.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:536808", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536808", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZZ73-1", "protein_name": "Ras association domain-containing protein 3", "gene_name": "RASSF3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRAGQQDVEKEKETHSYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPSQSSPNPGKLAPSSNGYMNTLHISSTNTVGEVIEALLKKFLVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKERYAAYRHKLEEALGEAWKPG", "length": 238 }, "evidence": [ { "id": "A0ABI0NSH2", "url": "https://omabrowser.org/oma/group/A0ABI0NSH2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YHN5-1", "protein_name": "Ras association domain family member 3", "gene_name": "RASSF3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAIRSDFSKTIRRIARFFYRFPKSLGSSRRRTVKLLWKSTDCKYTCHAHCRDLVHLGCRRNGKLMDCLTAHGTLHGSDSDGQDVQKETEPHVYLSKEEVKEKIQSYNSSVTDKLKMTLNSNGIYTGFIKVQMELCRPITVQSSPGQGPCAHSNNETAFYLPNDCVNTLHISSTNTVREVIEALLKKFFVADNPAKFALYKRCHKEDQVYICKLSDREHPLYLRLVAGPRTEMLSFVLREHETGEVMWEAFSLPELQNFLRILDKEENEQLQILKKRYAAYRDKLEEALGGVWKPG", "length": 295 }, "evidence": [ { "id": "A0ABI0NSH2", "url": "https://omabrowser.org/oma/group/A0ABI0NSH2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ACL6-1", "protein_name": "Ras association domain-containing protein 3", "gene_name": "Rassf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSGYSSLEEDAEDFFFTARTSFFRRAPPGKSRSGQPDVEKEKETHNYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPAQTPANPSSSGCMNTLHISSTNTVGDVIDALLKKFQVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQSLKRRYTAYRQKLEEALGEVWKPG", "length": 233 }, "evidence": [ { "id": "A0ABI0NSH2", "url": "https://omabrowser.org/oma/group/A0ABI0NSH2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86WH2-1", "protein_name": "Ras association domain-containing protein 3", "gene_name": "RASSF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRRYTAYRQKLEEALREVWKPD", "length": 238 }, "evidence": [ { "id": "A0ABI0NSH2", "url": "https://omabrowser.org/oma/group/A0ABI0NSH2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99P51-1", "protein_name": "Ras association domain-containing protein 3", "gene_name": "Rassf3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSGYSSLEEDEDFFFTARTSFFRRAPPGKSRSGQPDVEKEKETHNYLSKEEIKEKVHKYNSAVTDKLKMTLNSNGIYTGFIKVQMELCKPAQPSPEPSSGGCMNTLHISSTNTVGEVIEALLRKFLVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQSLKRRYTAYRQKLEEALGEVWKPG", "length": 232 }, "evidence": [ { "id": "A0ABI0NSH2", "url": "https://omabrowser.org/oma/group/A0ABI0NSH2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSH2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSH2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NSH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH2" }, { "id": "PS50200", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-associating", "eco_id": "ECO_0000259", "start_pos": 106, "end_pos": 211, "start_aa": "Tyr", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NSH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH2" }, { "id": "PS50951", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50951" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SARAH", "eco_id": "ECO_0000259", "start_pos": 211, "end_pos": 258, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NTZ1-1", "uniprot_ac": "A0ABI0NTZ1", "uniprot_id": "A0ABI0NTZ1_BOVIN", "mass": { "chemical_mass": 35449.0, "monoisotopic_mass": 35449.0 }, "refseq": { "ac": "XP_024855055", "name": "uncharacterized protein C2orf92 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855055" }, "gene_names": [ { "name": "C11H2orf92", "type": "recommended", "evidence": [ { "id": "A0ABI0NTZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ1" } ] }, { "name": "C11H2orf92", "type": "synonym", "evidence": [ { "id": "XP_024855055", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855055" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0ABI0NTZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C2orf92 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024855055", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855055" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTZ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "C11H2orf92", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ1", "locus": {} } ], "crossref": [ { "id": "783105", "url": "https://www.ncbi.nlm.nih.gov/gene/783105", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "XP_024855055", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855055", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TL35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TL35-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTZ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZK2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKKREAEALFFVLFLDYWQGSNAESSSNSKILDKGLAKLFDEILLQVFSKVPLEETRRTADRSITKRDMQESYPSQKSSRETDFALSSNKRDEHLAKLFDEILLQVFSKVPLEETRAAAGRSITKRDTKERATVDGNSHEPEFFFDSTGRMSNNENNPADDQNHNPPHVENISQTLRRSSDHIAEEQRDQESSLFNRDVSDTQSTTINKGTLQEAVSPDIPSRGMPCSQLLQFLQKNIIIAAVSVVGIVTATGLLLLALVMYIRKKQSLRSPADITYNIFIMNGKTWWQKSQDKKTKKHAGKQKRLKLNAGI", "length": 313, "header": "tr|A0ABI0NTZ1-1|A0ABI0NTZ1_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=C11H2orf92 PE=4 SV=1 CANONICAL=A0ABI0NTZ1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TL35-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ1/entry#A0AAA9TL35-1", "sequence": { "sequence": "MLNLHQIQKFWTKDWLNSLMKFYCKCFPKFHKKQEEQQTDQLQRETCKKASYPSQKSSRETDFALSSNKRDEHLAKLFGATVDGNSHEPEFFFDSTGRMSNNDHIAEEQRDQESSLFNRDVSDTQSTTINKGTLQEAVSPDVLRQTSHTIFL", "length": 152, "header": "tr|A0AAA9TL35-1|A0ABI0NTZ1_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN=C11H2orf92 PE=4 SV=1 CANONICAL=A0ABI0NTZ1-1" }, "locus": { "chromosome": "11", "start_pos": 3032109, "end_pos": 2994973, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127948.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127948.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097664.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097664.1" } ] } }, { "isoform_ac": "A0ABI0NTZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ1/entry#A0ABI0NTZ1-1", "sequence": { "sequence": "MAKKREAEALFFVLFLDYWQGSNAESSSNSKILDKGLAKLFDEILLQVFSKVPLEETRRTADRSITKRDMQESYPSQKSSRETDFALSSNKRDEHLAKLFDEILLQVFSKVPLEETRAAAGRSITKRDTKERATVDGNSHEPEFFFDSTGRMSNNENNPADDQNHNPPHVENISQTLRRSSDHIAEEQRDQESSLFNRDVSDTQSTTINKGTLQEAVSPDIPSRGMPCSQLLQFLQKNIIIAAVSVVGIVTATGLLLLALVMYIRKKQSLRSPADITYNIFIMNGKTWWQKSQDKKTKKHAGKQKRLKLNAGI", "length": 313, "header": "tr|A0ABI0NTZ1-1|A0ABI0NTZ1_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=C11H2orf92 PE=4 SV=1 CANONICAL=A0ABI0NTZ1-1" }, "locus": { "chromosome": "11", "start_pos": 3032204, "end_pos": 2991039, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152877.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152877.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107145.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107145.1" } ] } }, { "isoform_ac": "A0ABI0NYQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ1/entry#A0ABI0NYQ4-1", "sequence": { "sequence": "NSTASVFQSSIRRNKKNSRQINYKERHARNTSPFSVSASHFGYPSQKSSRETDFALSSNKRDEHLAKLFDEILLQVFSKVPLEETRAAAGRSITKRDTKEKNNPADDQNHNPPHVENISQTLRRSSDHIAEEQRDQESSLFNRDVSDTQSTTINKGTLQEAVSPDIPSRGMPCSQLLQFLQKNIIIAAVSVVGIVTATGLLLLALVMYIRKKQSLRSPADITYNIFIMNGKTWWQKSQDKKTKKHAGKQKRLKLNAGI", "length": 258, "header": "tr|A0ABI0NYQ4-1|A0ABI0NYQ4_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN=C11H2orf92 PE=4 SV=1 CANONICAL=A0ABI0NTZ1-1" }, "locus": { "chromosome": "11", "start_pos": 3032204, "end_pos": 3004811, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154286.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154286.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107471.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107471.1" } ] } }, { "isoform_ac": "A0ABI0NZK2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ1/entry#A0ABI0NZK2-1", "sequence": { "sequence": "AALQKPPAPLAHCPLLPRKGLLSSSLQVTTGSNAESSSNSKILDKGLAKLFGYPSQKSSRETDFALSSNKRDEHLAKLFDEILLQVFSKVPLEETRAAAGRSITKRDTKEKNNPADDQNHNPPHVENISQTLRRSSDHIAEEQRDQESSLFNRDVSDTQSTTINKGTLQEAVSPDIPSRGMPCSQLLQFLQKNIIIAAVSVVGIVTATGLLLLALVMYIRKKQSLRSPADITYNIFIMNGKTWWQKSQDKKTKKHAGKQKRLKLNAGI", "length": 268, "header": "tr|A0ABI0NZK2-1|A0ABI0NZK2_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN=C11H2orf92 PE=4 SV=1 CANONICAL=A0ABI0NTZ1-1" }, "locus": { "chromosome": "11", "start_pos": 3032204, "end_pos": 2974929, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145863.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145863.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105929.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105929.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQE9-1", "uniprot_ac": "A0ABI0NQE9", "uniprot_id": "A0ABI0NQE9_BOVIN", "mass": { "chemical_mass": 66927.0, "monoisotopic_mass": 66927.0 }, "refseq": { "ac": "XP_005213895", "name": "protein aurora borealis isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213895" }, "gene_names": [ { "name": "BORA", "type": "recommended", "evidence": [ { "id": "A0ABI0NQE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9" } ] }, { "name": "BORA", "type": "synonym", "evidence": [ { "id": "XP_005213895", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213895" } ] }, { "name": "C12H13orf34", "type": "synonym", "evidence": [ { "id": "XP_005213895", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213895" } ] } ], "protein_names": [ { "name": "Protein aurora borealis", "type": "recommended", "evidence": [ { "id": "A0ABI0NQE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9/entry#names_and_taxonomy" } ] }, { "name": "protein aurora borealis isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005213895", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213895" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQE9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BORA", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9", "locus": { "chromosome": "12", "start_pos": 47505656, "end_pos": 47476225, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019886", "url": "https://www.ensembl.org/id/ENSBTAG00000019886" } ] } } ], "crossref": [ { "id": "ENSBTAG00000019886", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019886", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "514162", "url": "https://www.ncbi.nlm.nih.gov/gene/514162", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514162", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514162", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1N3C9", "url": "https://www.orthodb.org/?gene=F1N3C9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14728", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14728", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14728:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14728:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15280", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15280", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-69273", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-69273", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005213895", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213895", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TRH9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRH9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYE1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYE1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQE9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQE9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3C9", "url": "https://www.uniprot.org/uniprotkb/F1N3C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3C9-1", "url": "https://www.uniprot.org/uniprotkb/F1N3C9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPSALELWTIPWEDLQRCRPGQEVDLKSSWAQPRPRALALGNRGKFFLCAMGDVKESKMQITPETPGRIPVLNPFESPGDYSNLHEQTVSSPSVFKSTKLPTPGEFRWSIDQLAVINPVEIDPEDIHRQALYLSRSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHEGKQLSEYHSSKCINTNNESPVGRKLTIHSEKSNAACQTLLSLPVDFNLEKILGDYFRADEFADQSPGNLSSSSLRRKLFLDGNGSISDSLPPASPRSPRSGAQTSLEVFYSIELSPVQCRSPVQTPSSGQFSSSPIQDSAKRYSLGSITNPSPISSPTFSPVAFQIGKTPLSEQRKFAFHSPDASSGTNCNGITNPYIRSPYIDGCSPIKNWSPMRLEMCRGGAQYRTSLIRVPFTLEARSEEEEDQAAVPSTDASAPVTGMAGVHLPQLGSDTSPCGAHLVVTAMSITQSQSGASEKELELLQDVESEKKNNTVDMVDPIEIADETTWIKEPVHNGNLPAADSVSGMAFSIENSHMCLSPLAESSVLPCESSNIQMDSGYNTQNCGSNIMDTVGAESYCKESDAQTLEVENKSRVFNTKQDHSMQRCWMKTSNLPQCSSP", "length": 610, "header": "tr|A0ABI0NQE9-1|A0ABI0NQE9_BOVIN Isoform 1 of Protein aurora borealis OS=Bos taurus OX=9913 GN=BORA PE=3 SV=1 CANONICAL=A0ABI0NQE9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TRH9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9/entry#A0AAA9TRH9-1", "sequence": { "sequence": "MGDVKESKMQITPETPGRIPVLNPFESPGDYSNLHEQTVSSPSVFKSTKLPTPGEFRWSIDQLAVINPVEIDPEDIHRQALYLSRSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHEGKQLSEYHSSKCINTNNESPVGRKLTIHSEKSNAACQTLLSLPVDFNLEKILGDYFRADEFADQSPGNLSSSSLRRKLFLDGNGSISDSLPPASPRSPRSGAQTSLEVFYSIELSPVQCRSPVQTPSSGQFSSSPIQDSAKRYSLGSITNPSPISSPTFSPVAFQIGKTPLSEQRKFAFHSPDASSGTNCNGITNPYIRSPYIDGCSPIKNWSPMRLEMCRGGAQYRTSLIRVPFTLEARSEEEEDQAAVPSTDASAPVTGMAGVHLPQLGSDTSPCGAHLVVTAMSITQSQSGASEKELELLQDVESEKKNNTVDMVDPIEIADETTWIKEPVHNGNLPAADSVSGMAFSIENSHMCLSPLAESSVLPCESSNIQMDSGYNTQNCGSNIMDTVGAESYCKESDAQTLEVENKSRVFNTKQDHSMQRCWMKTSNLPQCSSP", "length": 559, "header": "tr|A0AAA9TRH9-1|A0ABI0NQE9_BOVIN Computationally mapped isoform of Protein aurora borealis OS=Bos taurus OX=9913 GN=BORA PE=3 SV=2 CANONICAL=A0ABI0NQE9-1" }, "locus": { "chromosome": "12", "start_pos": 47504334, "end_pos": 47478324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098813.2", "url": "https://www.ensembl.org/id/ENSBTAT00000098813.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099058.2", "url": "https://www.ensembl.org/id/ENSBTAP00000099058.2" } ] } }, { "isoform_ac": "A0AAA9TYE1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9/entry#A0AAA9TYE1-1", "sequence": { "sequence": "MNKLSPVLLFLNRQNYQIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHEGKQLSEYHSSKCINTNNESPVGRKLTIHSEKSNAACQTLLSLPVDFNLEKILGDYFRADEFADQSPGNLSSSSLRRKLFLDGNGSISDSLPPASPRSPRSGAQTSLEVFYSIELSPVQCRSPVQTPSSGQFSSSPIQDSAKRYSLGSITNPSPISSPTFSPVAFQIGKTPLSEQRKFAFHSPDASSGTNCNGITNPYIRSPYIDGCSPIKNWSPMRLEMCRGGAQYRTSLIRVPFTLEARSEEEEDQAAVPSTDASAPVTGMAGVHLPQLGSDTSPCGAHLVVTAMSITQSQSGASEKELELLQDVESEKKNNTVDMVDPIEIADETTWIKEPVHNGNLPAADSVSGMAFSIENSHMCLSPLAESSVLPCESSNIQMDSGYNTQNCGSNIMDTVGAESYCKESDAQTLEVENKSRVFNTKQDHSMQRCWMKTSNLPQCSSP", "length": 489, "header": "tr|A0AAA9TYE1-1|A0ABI0NQE9_BOVIN Computationally mapped isoform of Protein aurora borealis OS=Bos taurus OX=9913 GN=BORA PE=3 SV=1 CANONICAL=A0ABI0NQE9-1" }, "locus": { "chromosome": "12", "start_pos": 47504334, "end_pos": 47478427, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133186.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133186.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101697.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101697.1" } ] } }, { "isoform_ac": "A0ABI0NQE9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9/entry#A0ABI0NQE9-1", "sequence": { "sequence": "MGPSALELWTIPWEDLQRCRPGQEVDLKSSWAQPRPRALALGNRGKFFLCAMGDVKESKMQITPETPGRIPVLNPFESPGDYSNLHEQTVSSPSVFKSTKLPTPGEFRWSIDQLAVINPVEIDPEDIHRQALYLSRSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHEGKQLSEYHSSKCINTNNESPVGRKLTIHSEKSNAACQTLLSLPVDFNLEKILGDYFRADEFADQSPGNLSSSSLRRKLFLDGNGSISDSLPPASPRSPRSGAQTSLEVFYSIELSPVQCRSPVQTPSSGQFSSSPIQDSAKRYSLGSITNPSPISSPTFSPVAFQIGKTPLSEQRKFAFHSPDASSGTNCNGITNPYIRSPYIDGCSPIKNWSPMRLEMCRGGAQYRTSLIRVPFTLEARSEEEEDQAAVPSTDASAPVTGMAGVHLPQLGSDTSPCGAHLVVTAMSITQSQSGASEKELELLQDVESEKKNNTVDMVDPIEIADETTWIKEPVHNGNLPAADSVSGMAFSIENSHMCLSPLAESSVLPCESSNIQMDSGYNTQNCGSNIMDTVGAESYCKESDAQTLEVENKSRVFNTKQDHSMQRCWMKTSNLPQCSSP", "length": 610, "header": "tr|A0ABI0NQE9-1|A0ABI0NQE9_BOVIN Isoform 1 of Protein aurora borealis OS=Bos taurus OX=9913 GN=BORA PE=3 SV=1 CANONICAL=A0ABI0NQE9-1" }, "locus": { "chromosome": "12", "start_pos": 47504334, "end_pos": 47476380, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139260.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139260.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105561.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105561.1" } ] } }, { "isoform_ac": "F1N3C9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9/entry#F1N3C9-1", "sequence": { "sequence": "MGDVKESKMQITPETPGRIPVLNPFESPGDYSNLHEQTVSSPSVFKSTKLPTPGEFRWSIDQLAVINPVEIDPEDIHRQALYLSRSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHEGKQLSEYHSSKCINTNNESPVGRKLTIHSEKSNAACQTLLSLPVDFNLEKILGDYFRADEFADQSPGNLSSSSLRRKLFLDGNGSISDSLPPASPRSPRSGAQTSLEVFYSIELSPVQCRSPVQTPSSILFPRKLLRNIEYSSLCYTGQFSSSPIQDSAKRYSLGSITNPSPISSPTFSPVAFQIGKTPLSEQRKFAFHSPDASSGTNCNGITNPYIRSPYIDGCSPIKNWSPMRLEMCRGGAQYRTSLIRVPFTLEARSEEEEDQAAVPSTDASAPVTGMAGVHLPQLGSDTSPCGAHLVVTAMSITQSQSGASEKELELLQDVESEKKNNTVDMVDPIEIADETTWIKEPVHNGNLPAADSVSGMAFSIENSHMCLSPLAESSVLPCESSNIQMDSGYNTQNCGSNIMDTVGAESYCKESDAQTLEVENKSRVFNTKQDHSMQRCWMKTSNLPQCSSP", "length": 578, "header": "tr|F1N3C9-1|A0ABI0NQE9_BOVIN Computationally mapped isoform of Protein aurora borealis OS=Bos taurus OX=9913 GN=BORA PE=3 SV=3 CANONICAL=A0ABI0NQE9-1" }, "locus": { "chromosome": "12", "start_pos": 47504334, "end_pos": 47478324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026496.6", "url": "https://www.ensembl.org/id/ENSBTAT00000026496.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026496.6", "url": "https://www.ensembl.org/id/ENSBTAP00000026496.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514162", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514162", "resource": "KEGG Pathway" }, { "id": "R-BTA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-BTA-69273", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-69273", "resource": "Reactome", "description": "Cyclin A/B1/B2 associated events during G2/M transition" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQE9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9" } ], "pmid": "" }, { "name": "regulation of mitotic spindle organization", "id": "GO:0060236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060236", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQE9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9" } ], "pmid": "" }, { "name": "regulation of mitotic nuclear division", "id": "GO:0007088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007088", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQE9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQE9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQE9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQE9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 237, "end_pos": 239 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 481, "end_pos": 483 }, { "start_pos": 581, "end_pos": 583 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQE0-1", "uniprot_ac": "A0ABI0NQE0", "uniprot_id": "A0ABI0NQE0_BOVIN", "mass": { "chemical_mass": 33230.0, "monoisotopic_mass": 33230.0 }, "refseq": {}, "gene_names": [ { "name": "CENPBD1", "type": "recommended", "evidence": [ { "id": "A0ABI0NQE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE0" } ] } ], "protein_names": [ { "name": "HTH CENPB-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NQE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQE0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CENPBD1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE0", "locus": {} } ], "crossref": [ { "id": "IPR004875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19303", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19303", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19303:SF59", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19303:SF59", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03221", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03221", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04218", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04218", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TVH8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVH8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQE0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQE0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGKRSLNAAVIRSAKRERKAITLDVKLEVLRRFEVGEKLSQIAKALGLAASTVATIRDNKDKIKASSQIATPLRASRLTRRRSAVMETMERLLCVWLEDESQRNVPLSVTVIQKKAKSLFDDLQREQGESSQTEKFTASKGWFVRFKERHCLPHFKMNISAPAKKDEYPEILKSIIQEGEYTPQQVFNVDETGLYWKRMPERMFLSVEERAEPGFKSSKDRLMLLLGGNAAGDFKLKPLLVYHSENPKALKGYSKPNLPVIWRSSRKAWATRSIFHEWFTYFFCPAIE", "length": 289, "header": "tr|A0ABI0NQE0-1|A0ABI0NQE0_BOVIN Isoform 1 of HTH CENPB-type domain-containing protein OS=Bos taurus OX=9913 GN=CENPBD1 PE=3 SV=1 CANONICAL=A0ABI0NQE0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TVH8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE0/entry#A0AAA9TVH8-1", "sequence": { "sequence": "MTGKRSLNAAVIRSAKRERKAITLDVKLEVLRRFEVGEKLSQIAKALGLAASTVATIRDNKDKIKASSQIATPLRASRLTRRRSAVMETMERLLCVWLEDESQRNVPLSVTVIQKKAKSLFDDLQREQGESSQTEKFTASKGWFVRFKERHCLPHFKMNISAPAKKDEYPEILKSIIQEGGYTSNKRKYRCMDFVAALFVTSKPRK", "length": 206, "header": "tr|A0AAA9TVH8-1|A0ABI0NQE0_BOVIN Computationally mapped isoform of HTH CENPB-type domain-containing protein OS=Bos taurus OX=9913 GN=CENPBD1 PE=3 SV=1 CANONICAL=A0ABI0NQE0-1" }, "locus": { "chromosome": "18", "start_pos": 14741812, "end_pos": 14739094, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096213.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096213.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100581.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100581.1" } ] } }, { "isoform_ac": "A0ABI0NQE0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE0/entry#A0ABI0NQE0-1", "sequence": { "sequence": "MTGKRSLNAAVIRSAKRERKAITLDVKLEVLRRFEVGEKLSQIAKALGLAASTVATIRDNKDKIKASSQIATPLRASRLTRRRSAVMETMERLLCVWLEDESQRNVPLSVTVIQKKAKSLFDDLQREQGESSQTEKFTASKGWFVRFKERHCLPHFKMNISAPAKKDEYPEILKSIIQEGEYTPQQVFNVDETGLYWKRMPERMFLSVEERAEPGFKSSKDRLMLLLGGNAAGDFKLKPLLVYHSENPKALKGYSKPNLPVIWRSSRKAWATRSIFHEWFTYFFCPAIE", "length": 289, "header": "tr|A0ABI0NQE0-1|A0ABI0NQE0_BOVIN Isoform 1 of HTH CENPB-type domain-containing protein OS=Bos taurus OX=9913 GN=CENPBD1 PE=3 SV=1 CANONICAL=A0ABI0NQE0-1" }, "locus": { "chromosome": "18", "start_pos": 14741812, "end_pos": 14740946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151502.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151502.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104413.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104413.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQE0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQE0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NQE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE0" }, { "id": "PRU00320", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00320" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "H-T-H motif", "eco_id": "ECO_0000256", "start_pos": 40, "end_pos": 60, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NQE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE0" }, { "id": "PS51253", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51253" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH CENPB-type", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 157, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NQE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQE0" }, { "id": "PS50960", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50960" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH psq-type", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 64, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NMH2-1", "uniprot_ac": "A0ABI0NMH2", "uniprot_id": "A0ABI0NMH2_BOVIN", "mass": { "chemical_mass": 59370.0, "monoisotopic_mass": 59370.0 }, "refseq": { "ac": "NP_001193433", "name": "RNA-binding protein 39", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193433" }, "gene_names": [ { "name": "RBM39", "type": "recommended", "evidence": [ { "id": "A0ABI0NMH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2" } ] }, { "name": "RBM39", "type": "synonym", "evidence": [ { "id": "NP_001193433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193433" } ] } ], "protein_names": [ { "name": "RNA-binding protein 39", "type": "recommended", "evidence": [ { "id": "A0ABI0NMH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding motif protein 39", "type": "synonym", "evidence": [ { "id": "A0ABI0NMH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein 39", "type": "synonym", "evidence": [ { "id": "NP_001193433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193433" } ] }, { "name": "RNA-binding region (RNP1, RRM) containing 2", "type": "synonym", "evidence": [ { "id": "NP_001193433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193433" } ] } ], "function": [ { "annotation": "RNA-binding protein that acts as a pre-mRNA splicing factor. Acts by promoting exon inclusion via regulation of exon cassette splicing. Also acts as a transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1, independently of the pre-mRNA splicing factor activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LWZ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWZ4#function" }, { "database": "UniProtKB", "id": "ARBA00056518", "url": "https://www.uniprot.org/uniprotkb/ARBA00056518#function" }, { "database": "UniProtKB", "id": "A0ABI0NMH2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2#function" } ] }, { "annotation": "Theileria annulata subtelomere-encoded variable secreted protein-TA05560 interacts with bovine RNA binding motif protein 39 (RBM39).", "evidence": [ { "database": "RefSeq", "id": "NP_001193433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193433" }, { "database": "PubMed", "id": "38280638", "url": "https://glygen.org/publication/PubMed/38280638" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMH2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RBM39", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2", "locus": { "chromosome": "13", "start_pos": 64908243, "end_pos": 64928396, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003949", "url": "https://www.ensembl.org/id/ENSBTAG00000003949" } ] } } ], "crossref": [ { "id": "ENSBTAG00000003949", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003949", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12284", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12284", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12285", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12285", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12537", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12537", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "508722", "url": "https://www.ncbi.nlm.nih.gov/gene/508722", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:508722", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508722", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LWZ4", "url": "https://www.orthodb.org/?gene=A0A3Q1LWZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15519", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15519", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2980766", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2980766", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2995383", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2995383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4419969", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4419969", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9696273", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696273", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001193433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193433", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWZ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW64", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW64-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMH2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMH2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADDIDIEAMLEAPYKKVRKNKSDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLMARLAEGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR", "length": 530, "header": "tr|A0ABI0NMH2-1|A0ABI0NMH2_BOVIN Isoform 1 of RNA-binding protein 39 OS=Bos taurus OX=9913 GN=RBM39 PE=1 SV=1 CANONICAL=A0ABI0NMH2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LWZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2/entry#A0A3Q1LWZ4-1", "sequence": { "sequence": "MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLMARLAEGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR", "length": 508, "header": "tr|A0A3Q1LWZ4-1|A0ABI0NMH2_BOVIN Computationally mapped isoform of RNA-binding protein 39 OS=Bos taurus OX=9913 GN=RBM39 PE=1 SV=3 CANONICAL=A0ABI0NMH2-1" }, "locus": { "chromosome": "13", "start_pos": 64933877, "end_pos": 64909097, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074819.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074819.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060007.3", "url": "https://www.ensembl.org/id/ENSBTAP00000060007.3" } ] } }, { "isoform_ac": "A0AAA9TW64-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2/entry#A0AAA9TW64-1", "sequence": { "sequence": "MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKVLCIYLDLLTWKRSNPVIAKHLFSRDHITKKSKGPAQWTIYFNDVQYKIPLPLKTLESPF", "length": 94, "header": "tr|A0AAA9TW64-1|A0ABI0NMH2_BOVIN Computationally mapped isoform of RNA-binding protein 39 OS=Bos taurus OX=9913 GN=RBM39 PE=1 SV=1 CANONICAL=A0ABI0NMH2-1" }, "locus": { "chromosome": "13", "start_pos": 64933877, "end_pos": 64929547, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097801.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097801.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101680.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101680.1" } ] } }, { "isoform_ac": "A0ABI0NMH2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2/entry#A0ABI0NMH2-1", "sequence": { "sequence": "MADDIDIEAMLEAPYKKVRKNKSDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLMARLAEGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR", "length": 530, "header": "tr|A0ABI0NMH2-1|A0ABI0NMH2_BOVIN Isoform 1 of RNA-binding protein 39 OS=Bos taurus OX=9913 GN=RBM39 PE=1 SV=1 CANONICAL=A0ABI0NMH2-1" }, "locus": { "chromosome": "13", "start_pos": 64933877, "end_pos": 64909097, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136841.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136841.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106686.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106686.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Theileria annulata subtelomere-encoded variable secreted protein-TA05560 interacts with bovine RNA binding motif protein 39 (RBM39).", "journal": "Acta tropica", "date": "2024-04", "authors": "Ma Quanying, Han Yuan, Fu Yong, Teng Guixiang, Wang Xiaoqiang, Liu Junlong, Li Zhi", "evidence": [ { "database": "RefSeq", "id": "NP_001193433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193433" } ], "reference": [ { "type": "PubMed", "id": "38280638", "url": "https://glygen.org/publication/PubMed/38280638" } ] } ], "pathway": [ { "id": "bta:508722", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508722", "resource": "KEGG Pathway" }, { "id": "R-BTA-2980766", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2980766", "resource": "Reactome", "description": "Nuclear Envelope Breakdown" }, { "id": "R-BTA-2995383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2995383", "resource": "Reactome", "description": "Initiation of Nuclear Envelope (NE) Reformation" }, { "id": "R-BTA-4419969", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4419969", "resource": "Reactome", "description": "Depolymerization of the Nuclear Lamina" }, { "id": "R-BTA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-BTA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-BTA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" }, { "id": "R-BTA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" }, { "id": "R-BTA-9696264", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696264", "resource": "Reactome", "description": "RND3 GTPase cycle" }, { "id": "R-BTA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" }, { "id": "R-BTA-9696273", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696273", "resource": "Reactome", "description": "RND1 GTPase cycle" }, { "id": "R-BTA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "U1 snRNP binding", "id": "GO:1990446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990446", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMH2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMH2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMH2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMH2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" }, { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NMH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH2" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 159, "end_pos": 236, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 21, "end_pos": 23 }, { "start_pos": 266, "end_pos": 268 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"https://www.ncbi.nlm.nih.gov/protein/XP_003586557" } ] } ], "protein_names": [ { "name": "Apoptotic chromatin condensation inducer in the nucleus", "type": "recommended", "evidence": [ { "id": "A0ABI0NNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNR2/entry#names_and_taxonomy" } ] }, { "name": "apoptotic chromatin condensation inducer in the nucleus isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003586557", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586557" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNR2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNR2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ACIN1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNR2", "locus": { "chromosome": "10", "start_pos": 21800705, "end_pos": 21789602, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011571", "url": "https://www.ensembl.org/id/ENSBTAG00000011571" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011571", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011571", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12432", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12432", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "534600", "url": "https://www.ncbi.nlm.nih.gov/gene/534600", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032552", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032552", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034257", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034257", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534600", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534600", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6QIB4", "url": "https://www.orthodb.org/?gene=F6QIB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46589", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46589", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46589:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46589:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003586557", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586557", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NNR2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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"https://www.uniprot.org/uniprotkb/F6QIB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QIB4-1", "url": "https://www.uniprot.org/uniprotkb/F6QIB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCRRKHPSTSGGTRGALSGNRGVDYGSGRGQLGTFEGRWRKLPKMPEAVGTDPSTSRKMAELEEVTLDGKPLQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLENLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPERVASLLPPDFQSSLERPELELSRHSPRKSTSVSEEKGESDDEKPRKGERRSSRVRQARAAKLSECSQAAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEEEEEEDDDDEGQKSRDAPVLKQFKEEGEEIPIVKVEEVTDERPQTIRSQEQEGLERGGRVTRSQEEARRSHLARHQQEKEMKTASLEEEREIKSSKGLEEKSKSPSPPQLTEDVAKAPVVLQPELTASEEETPPPLLTKEASSPPPNTQLQSEEEIEPMEGPAPPVLIQLSPPNADAEARELLLSQHTVQLVGSLSPLSGPADTKVESPVEKVPEESVLPLVQKSAQAESSAQKGLETESEKSTQPLPLKIEEFTLAKGITEESLEQKEGRRASHALLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSQSHSPPRSKQRDGSGVRAHANPHDRSKVGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVAAPPLPQLQVLEPKERTSTPSSVQVRLVSQPEPAAKHVTQRLQPDRGSPKKCEAEEAEPPAATQPQTSETPTSHLPESERIHHTVEEKEEVTMDTSENRPENEVPEPPMPIADQVSNDDRPEGNAEDEEKKESLLPKSFKRKISVVSATKGVPAGNSDTEGGQPSRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEEEKEPEAEAPVPPQVSVEVALPPPVEHEVKKVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHRGLLVDRPSETKTEEQGMPRPLHPPPPPPAQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERTRQLEREKRREHSRERDRERERDRERDRGDRDRERDRERERGRERDRRDTKRHSRSRSRSTPVRDRGGRR", "length": 1334, "header": "tr|A0ABI0NNR2-1|A0ABI0NNR2_BOVIN Isoform 1 of Apoptotic chromatin condensation inducer in the nucleus OS=Bos taurus OX=9913 GN=ACIN1 PE=4 SV=1 CANONICAL=A0ABI0NNR2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NNR2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNR2/entry#A0ABI0NNR2-1", "sequence": { "sequence": "MCRRKHPSTSGGTRGALSGNRGVDYGSGRGQLGTFEGRWRKLPKMPEAVGTDPSTSRKMAELEEVTLDGKPLQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLENLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPERVASLLPPDFQSSLERPELELSRHSPRKSTSVSEEKGESDDEKPRKGERRSSRVRQARAAKLSECSQAAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEEEEEEDDDDEGQKSRDAPVLKQFKEEGEEIPIVKVEEVTDERPQTIRSQEQEGLERGGRVTRSQEEARRSHLARHQQEKEMKTASLEEEREIKSSKGLEEKSKSPSPPQLTEDVAKAPVVLQPELTASEEETPPPLLTKEASSPPPNTQLQSEEEIEPMEGPAPPVLIQLSPPNADAEARELLLSQHTVQLVGSLSPLSGPADTKVESPVEKVPEESVLPLVQKSAQAESSAQKGLETESEKSTQPLPLKIEEFTLAKGITEESLEQKEGRRASHALLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSQSHSPPRSKQRDGSGVRAHANPHDRSKVGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVAAPPLPQLQVLEPKERTSTPSSVQVRLVSQPEPAAKHVTQRLQPDRGSPKKCEAEEAEPPAATQPQTSETPTSHLPESERIHHTVEEKEEVTMDTSENRPENEVPEPPMPIADQVSNDDRPEGNAEDEEKKESLLPKSFKRKISVVSATKGVPAGNSDTEGGQPSRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEEEKEPEAEAPVPPQVSVEVALPPPVEHEVKKVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHRGLLVDRPSETKTEEQGMPRPLHPPPPPPAQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERTRQLEREKRREHSRERDRERERDRERDRGDRDRERDRERERGRERDRRDTKRHSRSRSRSTPVRDRGGRR", "length": 1334, "header": "tr|A0ABI0NNR2-1|A0ABI0NNR2_BOVIN Isoform 1 of Apoptotic chromatin condensation inducer in the nucleus OS=Bos taurus OX=9913 GN=ACIN1 PE=4 SV=1 CANONICAL=A0ABI0NNR2-1" }, "locus": { "chromosome": "10", "start_pos": 21800094, "end_pos": 21762262, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153623.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153623.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104556.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104556.1" } ] } }, { "isoform_ac": "A0ABI0NWJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNR2/entry#A0ABI0NWJ4-1", "sequence": { "sequence": "MCRRKHPSTSGGTRGALSGNRGVDYGSGRGQLGTFEGRWRKLPKMPEAVGTDPSTSRKMAELEEVTLDGKPLQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLENLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEGKSTSVSEEKGESDDEKPRKGERRSSRVRQARAAKLSECSQAAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEEEEEEDDDDEGQKSRDAPVLKQFKEEGEEIPIVKVEEVTDERPQTIRSQEQEGLERGGRVTRSQEEARRSHLARHQQEKEMKTASLEEEREIKSSKGLEEKSKSPSPPQLTEDVAKAPVVLQPELTASEEETPPPLLTKEASSPPPNTQLQSEEEIEPMEGPAPPVLIQLSPPNADAEARELLLSQHTVQLVGSLSPLSGPADTKVESPVEKVPEESVLPLVQKSAQAESSAQKGLETESEKSTQPLPLKIEEFTLAKGITEESLEQKEGRRASHALLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSQSHSPPRSKQRDGSGVRAHANPHDRSKVGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVAAPPLPQLQVLEPKERTSTPSSVQVRLVSQPEPAAKHVTQRLQPDRGSPKKCEAEEAEPPAATQPQTSETPTSHLPESERIHHTVEEKEEVTMDTSENRPENEVPEPPMPIADQVSNDDRPEGNAEDEEKKESLLPKSFKRKISVVSATKGVPAGNSDTEGGQPSRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEEEKEPEAEAPVPPQVSVEVALPPPVEHEVKKVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHRGLLVDRPSETKTEEQGMPRPLHPPPPPPAQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERTRQLEREKRREHSRERDRERERDRERDRGDRDRERDRERERGRERDRRDTKRHSRSRSRSTPVRDRGGRR", "length": 1294, "header": "tr|A0ABI0NWJ4-1|A0ABI0NWJ4_BOVIN Computationally mapped isoform of Apoptotic chromatin condensation inducer in the nucleus OS=Bos taurus OX=9913 GN=ACIN1 PE=4 SV=1 CANONICAL=A0ABI0NNR2-1" }, "locus": { "chromosome": "10", "start_pos": 21800094, "end_pos": 21762262, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143477.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143477.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104175.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104175.1" } ] } }, { "isoform_ac": "A0ABI0P5V9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNR2/entry#A0ABI0P5V9-1", "sequence": { "sequence": "MLSESKEGEEKEEVTMDTSENRPENEVPEPPMPIADQVSNDDRPEGNAEDEEKKESLLPKSFKRKISVVSATKGVPAGNSDTEGGQPSRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEEEKEPEAEAPVPPQVSVEVALPPPVEHEVKKVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHRGLLVDRPSETKTEEQGMPRPLHPPPPPPAQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERTRQLEREKRREHSRERDRERERDRERDRGDRDRERDRERERGRERDRRDTKRHSRSRSRSTPVRDRGGRR", "length": 581, "header": "tr|A0ABI0P5V9-1|A0ABI0P5V9_BOVIN Computationally mapped isoform of Apoptotic chromatin condensation inducer 1 OS=Bos taurus OX=9913 GN=ACIN1 PE=4 SV=1 CANONICAL=A0ABI0NNR2-1" }, "locus": { "chromosome": "10", "start_pos": 21800094, "end_pos": 21790200, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141764.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141764.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107207.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107207.1" } ] } }, { "isoform_ac": "A0ABI0P6F3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNR2/entry#A0ABI0P6F3-1", "sequence": { "sequence": "MPEAVGTDPSTSRKMAELEEVTLDGKPLQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLENLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPERVASLLPPDFQSSLERPELELSRHSPRKSTSVSEEKGESDDEKPRKGERRSSRVRQARAAKLSECSQAAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEEEEEEDDDDEGQKSRDAPVLKQFKEEGEEIPIVKVEEVTDERPQTIRSQEQEGLERGGRVTRSQEEARRSHLARHQQEKEMKTASLEEEREIKSSKGLEEKSKSPSPPQLTEDVAKAPVVLQPELTASEEETPPPLLTKEASSPPPNTQLQSEEEIEPMEGPAPPVLIQLSPPNADAEARELLLSQHTVQLVGSLSPLSGPADTKVESPVEKVPEESVLPLVQKSAQAESSAQKGLETESEKSTQPLPLKIEEFTLAKGITEESLEQKEGRRASHALLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSQSHSPPRSKQRDGSGVRAHANPHDRSKVGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVAAPPLPQLQVLEPKERTSTPSSVQVRLVSQPEPAAKHVTQRLQPDRGSPKKCEAEEAEPPAATQPQTSETPTSHLPESERIHHTVEEKEEVTMDTSENRPENEVPEPPMPIADQVSNDDRPEGNAEDEEKKESLLPKSFKRKISVVSATKGVPAGNSDTEGGQPSRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEEEKEPEAEAPVPPQVSVEVALPPPVEHEVKKVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHRGLLVDRPSETKTEEQGMPRPLHPPPPPPAQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERTRQLEREKRREHSRERDRERERDRERDRGDRDRERDRERERGRERDRRDTKRHSRSRSRSTPVRDRGGRR", "length": 1290, "header": "tr|A0ABI0P6F3-1|A0ABI0P6F3_BOVIN Computationally mapped isoform of Apoptotic chromatin condensation inducer in the nucleus OS=Bos taurus OX=9913 GN=ACIN1 PE=4 SV=1 CANONICAL=A0ABI0NNR2-1" }, "locus": { "chromosome": "10", "start_pos": 21800094, "end_pos": 21762394, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150987.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150987.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107063.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107063.1" } ] } }, { "isoform_ac": "F6QIB4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNR2/entry#F6QIB4-1", "sequence": { "sequence": "MSPADRHRSASTIEPATTSSLALLLLLLQRDQSSRIRGLPEEKEEVTMDTSENRPENEVPEPPMPIADQVSNDDRPEGNAEDEEKKESLLPKSFKRKISVVSATKGVPAGNSDTEGGQPSRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEEEKEPEAEAPVPPQVSVEVALPPPVEHEVKKVTLGDTLTRRSISQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEAFWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHRGLLVDRPSETKTEEQGMPRPLHPPPPPPAQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERTRQLEREKRREHSRERDRERERDRERDRGDRDRERDRERERGRERDRRDTKRHSRSRSRSTPVRDRGGRR", "length": 613, "header": "tr|F6QIB4-1|A0ABI0NNR2_BOVIN Computationally mapped isoform of Apoptotic chromatin condensation inducer in the nucleus OS=Bos taurus OX=9913 GN=ACIN1 PE=4 SV=2 CANONICAL=A0ABI0NNR2-1" }, "locus": { "chromosome": "10", "start_pos": 21800094, "end_pos": 21789801, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002488.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002488.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002488.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002488.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:534600", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534600", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNR2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNR2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNR2" }, { "id": "PS50800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAP", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 106, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQP1-1", "uniprot_ac": "A0ABI0NQP1", "uniprot_id": "A0ABI0NQP1_BOVIN", "mass": { "chemical_mass": 30881.0, "monoisotopic_mass": 30881.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Peptidase S1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NQP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQP1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQP1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQP1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQP1", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000046722", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046722", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3MXR7", "url": "https://www.orthodb.org/?gene=G3MXR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24253", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24253", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24253:SF144", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24253:SF144", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NQP1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQP1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXR7", "url": "https://www.uniprot.org/uniprotkb/G3MXR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXR7-1", "url": "https://www.uniprot.org/uniprotkb/G3MXR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "APQDHLHMLWPLSGSLMAPYIASPGPGSGRELVGIVGGCDVSARSYLWQVSLRFYNRTAGLWIHFCGGSLIHPQWVLTAAHCVKPQKASTIRVQVGQLRLYDHDELTKVSKIVQHPDYDQILSAEGGADIALLRLEAPVSLSSHVQVVSLPPASLTVPERKMCWVSGWGKVTVHSPLPPPYHLQEVEVPIVGNQVCNQHYQKLENSTKPIKDDMLCAGSKGQDSCKGDSGGALVCLWKCSWVQVGVVSWGHKCALPDFPGVYTRVTSYMSWIRQYVPLSPGP", "length": 282, "header": "tr|A0ABI0NQP1-1|A0ABI0NQP1_BOVIN Isoform 1 of Peptidase S1 domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NQP1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NQP1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQP1/entry#A0ABI0NQP1-1", "sequence": { "sequence": "APQDHLHMLWPLSGSLMAPYIASPGPGSGRELVGIVGGCDVSARSYLWQVSLRFYNRTAGLWIHFCGGSLIHPQWVLTAAHCVKPQKASTIRVQVGQLRLYDHDELTKVSKIVQHPDYDQILSAEGGADIALLRLEAPVSLSSHVQVVSLPPASLTVPERKMCWVSGWGKVTVHSPLPPPYHLQEVEVPIVGNQVCNQHYQKLENSTKPIKDDMLCAGSKGQDSCKGDSGGALVCLWKCSWVQVGVVSWGHKCALPDFPGVYTRVTSYMSWIRQYVPLSPGP", "length": 282, "header": "tr|A0ABI0NQP1-1|A0ABI0NQP1_BOVIN Isoform 1 of Peptidase S1 domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NQP1-1" }, "locus": { "chromosome": "25", "start_pos": 1011888, "end_pos": 1010113, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140178.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140178.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104663.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104663.1" } ] } }, { "isoform_ac": "G3MXR7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQP1/entry#G3MXR7-1", "sequence": { "sequence": "MLLCPGSGASMGRELVGIVGGCDVSARSYLWQVSLRFYNRTAGLWIHFCGGSLIHPQWVLTAAHCVKPQKASTIRVQVGQLRLYDHDELTKVSKIVQHPDYDQILSAEGGADIALLRLEAPVSLSSHVQVVSLPPASLTVPERKMCWVSGWGKVTVHSPLPPPYHLQEVEVPIVGNQVCNQHYQKLENSTKPIKDDMLCAGSKGQDSCKGDSGGALVCLWKCSWVQVGVVSWGHKCALPDFPGVYTRVTSYMSWIRQYVPLSPGP", "length": 265, "header": "tr|G3MXR7-1|A0ABI0NQP1_BOVIN Computationally mapped isoform of Peptidase S1 domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=A0ABI0NQP1-1" }, "locus": { "chromosome": "25", "start_pos": 1012455, "end_pos": 1010113, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066317.4", "url": "https://www.ensembl.org/id/ENSBTAT00000066317.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054336.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054336.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQP1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQP1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQP1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQP1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQP1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NQP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQP1" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 277, "start_aa": "Ile", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 }, { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NPE1-1", "uniprot_ac": "A0ABI0NPE1", "uniprot_id": "A0ABI0NPE1_BOVIN", "mass": { "chemical_mass": 51979.0, "monoisotopic_mass": 51979.0 }, "refseq": {}, "gene_names": [ { "name": "CTSC", "type": "recommended", "evidence": [ { "id": "A0ABI0NPE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1" } ] } ], "protein_names": [ { "name": "Dipeptidyl peptidase 1", "type": "recommended", "evidence": [ { "id": "A0ABI0NPE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1/entry#names_and_taxonomy" } ] }, { "name": "3.4.14.1", "type": "synonym", "evidence": [ { "id": "A0ABI0NPE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1/entry#names_and_taxonomy" } ] }, { "name": "Cathepsin C", "type": "synonym", "evidence": [ { "id": "A0ABI0NPE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1/entry#names_and_taxonomy" } ] }, { "name": "Cathepsin J", "type": "synonym", "evidence": [ { "id": "A0ABI0NPE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1/entry#names_and_taxonomy" } ] }, { "name": "Dipeptidyl peptidase I", "type": "synonym", "evidence": [ { "id": "A0ABI0NPE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1/entry#names_and_taxonomy" } ] }, { "name": "Dipeptidyl transferase", "type": "synonym", "evidence": [ { "id": "A0ABI0NPE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serine proteases such as elastase, cathepsin G and granzymes A and B.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPE1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1#function" }, { "database": "UniProtKB", "id": "ARBA00045556", "url": "https://www.uniprot.org/uniprotkb/ARBA00045556#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPE1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CTSC", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1", "locus": { "chromosome": "29", "start_pos": 7415745, "end_pos": 7375413, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011100", "url": "https://www.ensembl.org/id/ENSBTAG00000011100" } ] } } ], "crossref": [ { "id": "cd02621", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02621", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014882", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014882", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12411", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12411", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00112", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00112", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9RYR4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYR4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SG54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SG54-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T2L4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T2L4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPE1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPE1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPWSGSRLVALLLLVYGAGSVRGDTPANCTYPDLLGTWVFQVGSSGSQRDVNCSVMGPPEKKVVVHLKKLDTAYDDFGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGGKVTSYCHETMTGWVHDVLGRNWACFTGRKTGNTSENVNVNTARLAGLEETYSNRLYRYNHDFVKAINAIQKSWTAAPYMEYETLTLKEMIRRGGGHSRRIPRPKPAPITAEIQKKILHLPTSWDWRNVHGINFVTPVRNQGSCGSCYSFASMGMMEARIRILTNNTQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEDCFPYTGTDSPCRLKEGCFRYYSSEYHYVGGFYGGCNEALMKLELVHQGPMAVAFEVYDDFLHYRKGVYHHTGLRDPFNPFELTNHAVLLVGYGTDAASGLDYWIVKNSWGTSWGENGYFRIRRGTDECAIESIALAATPIPKL", "length": 463, "header": "tr|A0ABI0NPE1-1|A0ABI0NPE1_BOVIN Isoform 1 of Dipeptidyl peptidase 1 OS=Bos taurus OX=9913 GN=CTSC PE=3 SV=1 CANONICAL=A0ABI0NPE1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RYR4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1/entry#A0AAA9RYR4-1", "sequence": { "sequence": "MGPWSGSRLVALLLLVYGAGSVRGDTPANCTYPDLLGTWVFQVGSSGSQRDVNCSVMGPPEKKVVVHLKKLDTAYDDFGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGGKVTSYCHETMTGWVHDVLGRNWACFTGRKTGNTSENVNVNTARLAGLEETYSNRLYRYNHDFVKAINAIQKSWTAAPYMEYETLTLKEMIRRGGGHSRRIPRPKPAPITAEIQKKILHLPTSWDWRNVHGINFVTPVRNQGCEGGFPYLIAGKYAQDFGLVEEDCFPYTGTDSPCRLKEGCFRYYSSEYHYVGGFYGGCNEALMKLELVHQGPMAVAFEVYDDFLHYRKGVYHHTGLRDPFNPFELTNHAVLLVGYGTDAASGLDYWIVKNSWGTSWGENGYFRIRRGTDECAIESIALAATPIPKL", "length": 419, "header": "tr|A0AAA9RYR4-1|A0ABI0NPE1_BOVIN Computationally mapped isoform of Dipeptidyl peptidase 1 OS=Bos taurus OX=9913 GN=CTSC PE=3 SV=1 CANONICAL=A0ABI0NPE1-1" }, "locus": { "chromosome": "29", "start_pos": 7415261, "end_pos": 7375472, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101703.2", "url": "https://www.ensembl.org/id/ENSBTAT00000101703.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076423.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076423.1" } ] } }, { "isoform_ac": "A0AAA9SG54-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1/entry#A0AAA9SG54-1", "sequence": { "sequence": "MGPWSGSRLVALLLLVYGAGSVRGDTPANCTYPDLLGTWVFQVGSSGSQRDVNCSVMGPPEKKVVVHLKKLDTAYDDFGNSGHFTIIYNQGFEIVLNDYKWFAFFKLLNRASVERLF", "length": 117, "header": "tr|A0AAA9SG54-1|A0ABI0NPE1_BOVIN Computationally mapped isoform of Dipeptidyl peptidase 1 OS=Bos taurus OX=9913 GN=CTSC PE=3 SV=1 CANONICAL=A0ABI0NPE1-1" }, "locus": { "chromosome": "29", "start_pos": 7384477, "end_pos": 7375472, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121596.2", "url": "https://www.ensembl.org/id/ENSBTAT00000121596.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081457.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081457.1" } ] } }, { "isoform_ac": "A0AAA9T2L4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1/entry#A0AAA9T2L4-1", "sequence": { "sequence": "MGPWSGSRLVALLLLVYGAGSVRGDTPANCTYPDLLGTWVFQVGSSGSQRDVNCSVMGPPEKKVVVHLKKLDTAYDDFGNSGHFTIIYNQGFEIVLNDYKWFAFFKDVTDLISQFFMQLGTVGMYDIPHLRNKLAKNRLWG", "length": 141, "header": "tr|A0AAA9T2L4-1|A0ABI0NPE1_BOVIN Computationally mapped isoform of Dipeptidyl peptidase 1 OS=Bos taurus OX=9913 GN=CTSC PE=3 SV=1 CANONICAL=A0ABI0NPE1-1" }, "locus": { "chromosome": "29", "start_pos": 7384508, "end_pos": 7375472, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127306.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127306.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091973.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091973.1" } ] } }, { "isoform_ac": "A0ABI0NPE1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1/entry#A0ABI0NPE1-1", "sequence": { "sequence": "MGPWSGSRLVALLLLVYGAGSVRGDTPANCTYPDLLGTWVFQVGSSGSQRDVNCSVMGPPEKKVVVHLKKLDTAYDDFGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGGKVTSYCHETMTGWVHDVLGRNWACFTGRKTGNTSENVNVNTARLAGLEETYSNRLYRYNHDFVKAINAIQKSWTAAPYMEYETLTLKEMIRRGGGHSRRIPRPKPAPITAEIQKKILHLPTSWDWRNVHGINFVTPVRNQGSCGSCYSFASMGMMEARIRILTNNTQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEDCFPYTGTDSPCRLKEGCFRYYSSEYHYVGGFYGGCNEALMKLELVHQGPMAVAFEVYDDFLHYRKGVYHHTGLRDPFNPFELTNHAVLLVGYGTDAASGLDYWIVKNSWGTSWGENGYFRIRRGTDECAIESIALAATPIPKL", "length": 463, "header": "tr|A0ABI0NPE1-1|A0ABI0NPE1_BOVIN Isoform 1 of Dipeptidyl peptidase 1 OS=Bos taurus OX=9913 GN=CTSC PE=3 SV=1 CANONICAL=A0ABI0NPE1-1" }, "locus": { "chromosome": "29", "start_pos": 7415261, "end_pos": 7375472, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152452.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152452.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104853.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104853.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "dipeptidyl-peptidase activity", "id": "GO:0008239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008239", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPE1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1" } ], "pmid": "" }, { "name": "cysteine-type peptidase activity", "id": "GO:0008234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008234", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPE1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPE1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPE1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NPE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPE1" }, { "id": "SM00645", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00645" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase C1A papain C-terminal", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 458, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.14.1", "ec_name": "Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro.", "evidence": [ { "id": "3.4.14.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.14.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 53, "end_pos": 55 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NSA6-1", "uniprot_ac": "A0ABI0NSA6", "uniprot_id": "A0ABI0NSA6_BOVIN", "mass": { "chemical_mass": 139902.0, "monoisotopic_mass": 139902.0 }, "refseq": { "ac": "XP_024838835", "name": "ATP-dependent RNA helicase DHX30 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838835" }, "gene_names": [ { "name": "DHX30", "type": "recommended", "evidence": [ { "id": "A0ABI0NSA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ] }, { "name": "DHX30", "type": "synonym", "evidence": [ { "id": "XP_024838835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838835" } ] } ], "protein_names": [ { "name": "ATP-dependent RNA helicase DHX30", "type": "recommended", "evidence": [ { "id": "A0ABI0NSA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "A0ABI0NSA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6/entry#names_and_taxonomy" } ] }, { "name": "ATP-dependent RNA helicase DHX30 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024838835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838835" } ] }, { "name": "DEAH box protein 30", "type": "synonym", "evidence": [ { "id": "A0ABI0NSA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSA6", "url": 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"id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M7N2", "url": "https://www.orthodb.org/?gene=A0A3Q1M7N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N0J0", "url": "https://www.orthodb.org/?gene=F1N0J0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18934", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18934", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18934:SF257", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18934:SF257", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07717", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07717", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24995", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24995", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024838835", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838835", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M7N2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNL0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNL0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSA6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSA6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWI2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWI2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5V5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5V5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N0J0", "url": "https://www.uniprot.org/uniprotkb/F1N0J0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N0J0-1", "url": "https://www.uniprot.org/uniprotkb/F1N0J0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLKDSSPGFQLSLLARNVQPGLIQKRSGPTQAASVQTSPTPSSTHVCQPCPWRDHLSRIPETTVLVRPFPGVDVSPLGVVVCLRGPCGFTYIAGKPVRMASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHAPLRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLSTLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPVESSWISSELRLQGEDILPLGKDSGPLSDPITGKPYVPLSEAEELRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVIAGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPARGGALLFCTVGILLRKLQSNPSLEGVSHVVVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYPHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPIGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMAPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVSGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLRELRRALGRMVERSLRSELAALPPCVQEEHGQLLALLAELLRGPCGSFDVRKTADD", "length": 1253, "header": "tr|A0ABI0NSA6-1|A0ABI0NSA6_BOVIN Isoform 1 of ATP-dependent RNA helicase DHX30 OS=Bos taurus OX=9913 GN=DHX30 PE=3 SV=1 CANONICAL=A0ABI0NSA6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M7N2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6/entry#A0A3Q1M7N2-1", "sequence": { "sequence": "MASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHAPLRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLSTLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPVESSWISSELRLQGEDILPLGKDSGPLSDPITGKPYVPLSEAEELRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVIAGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPARGGALLFCTVGILLRKLQSNPSLEGVSHVVVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYPHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPIGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMAPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVSGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLRELRRALGRMVERSLRSELAALPPCVQEEHGQLLALLAELLRGPCGSFDVRKTADD", "length": 1154, "header": "tr|A0A3Q1M7N2-1|A0ABI0NSA6_BOVIN Computationally mapped isoform of ATP-dependent RNA helicase DHX30 OS=Bos taurus OX=9913 GN=DHX30 PE=3 SV=2 CANONICAL=A0ABI0NSA6-1" }, "locus": { "chromosome": "22", "start_pos": 51928223, "end_pos": 51910472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068918.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068918.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066402.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066402.2" } ] } }, { "isoform_ac": "A0ABI0NNL0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6/entry#A0ABI0NNL0-1", "sequence": { "sequence": "MFSLDSFRKDRAQHRQRQCKLPPPRLPPMCVNPAPGGTISRASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKDSHAPLRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLSTLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPVESSWISSELRLQGEDILPLGKDSGPLSDPITGKPYVPLSEAEELRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVIAGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPARGGALLFCTVGILLRKLQSNPSLEGVSHVVVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYPHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPIGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMAPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVSGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLRELRRALGRMVERSLRSELAALPPCVQEEHGQLLALLAELLRGPCGSFDVRKTADD", "length": 1103, "header": "tr|A0ABI0NNL0-1|A0ABI0NNL0_BOVIN Computationally mapped isoform of ATP-dependent RNA helicase DHX30 OS=Bos taurus OX=9913 GN=DHX30 PE=3 SV=1 CANONICAL=A0ABI0NSA6-1" }, "locus": { "chromosome": "22", "start_pos": 51934841, "end_pos": 51910472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148523.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148523.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107291.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107291.1" } ] } }, { "isoform_ac": "A0ABI0NSA6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6/entry#A0ABI0NSA6-1", "sequence": { "sequence": "MDLKDSSPGFQLSLLARNVQPGLIQKRSGPTQAASVQTSPTPSSTHVCQPCPWRDHLSRIPETTVLVRPFPGVDVSPLGVVVCLRGPCGFTYIAGKPVRMASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHAPLRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLSTLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPVESSWISSELRLQGEDILPLGKDSGPLSDPITGKPYVPLSEAEELRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVIAGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPARGGALLFCTVGILLRKLQSNPSLEGVSHVVVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYPHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPIGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMAPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVSGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLRELRRALGRMVERSLRSELAALPPCVQEEHGQLLALLAELLRGPCGSFDVRKTADD", "length": 1253, "header": "tr|A0ABI0NSA6-1|A0ABI0NSA6_BOVIN Isoform 1 of ATP-dependent RNA helicase DHX30 OS=Bos taurus OX=9913 GN=DHX30 PE=3 SV=1 CANONICAL=A0ABI0NSA6-1" }, "locus": { "chromosome": "22", "start_pos": 51935904, "end_pos": 51910472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145390.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145390.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106825.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106825.1" } ] } }, { "isoform_ac": "A0ABI0NWI2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6/entry#A0ABI0NWI2-1", "sequence": { "sequence": "MDLKDSSPGFQLSLLARNVQPGLIQKRSGPTQAASVQTSPTPSSTHVCQPCPWRDHLSRLNVNISNMAASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHAPLRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLSTLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPVESSWISSELRLQGEDILPLGKDSGPLSDPITGKPYVPLSEAEELRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVIAGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPARGGALLFCTVGILLRKLQSNPSLEGVSHVVVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYPHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPIGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMAPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVSGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLRELRRALGRMVERSLRSELAALPPCVQEEHGQLLALLAELLRGPCGSFDVRKTADD", "length": 1221, "header": "tr|A0ABI0NWI2-1|A0ABI0NWI2_BOVIN Computationally mapped isoform of ATP-dependent RNA helicase DHX30 OS=Bos taurus OX=9913 GN=DHX30 PE=3 SV=1 CANONICAL=A0ABI0NSA6-1" }, "locus": { "chromosome": "22", "start_pos": 51935904, "end_pos": 51910472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147022.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147022.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105332.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105332.1" } ] } }, { "isoform_ac": "A0ABI0P5V5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6/entry#A0ABI0P5V5-1", "sequence": { "sequence": "MFSLDSFRKDRAQHRQRQCKLPPPRLPPMCVNPAPGGTISRASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHAPLRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLSTLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPVESSWISSELRLQGEDILPLGKDSGPLSDPITGKPYVPLSEAEELRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVIAGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPARGGALLFCTVGILLRKLQSNPSLEGVSHVVVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYPHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPIGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMAPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVSGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLRELRRALGRMVERSLRSELAALPPCVQEEHGQLLALLAELLRGPCGSFDVRKTADD", "length": 1194, "header": "tr|A0ABI0P5V5-1|A0ABI0P5V5_BOVIN Computationally mapped isoform of ATP-dependent RNA helicase DHX30 OS=Bos taurus OX=9913 GN=DHX30 PE=3 SV=1 CANONICAL=A0ABI0NSA6-1" }, "locus": { "chromosome": "22", "start_pos": 51934841, "end_pos": 51910472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136797.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136797.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107043.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107043.1" } ] } }, { "isoform_ac": "F1N0J0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6/entry#F1N0J0-1", "sequence": { "sequence": "MATARRLMALAAGVSPRLRPLGPRAIGRQGGPRGLSTGCSRPDRTQEAAEAEAAPGEPGEGDGSVVNASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHAPLRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLSTLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPVESSWISSELRLQGEDILPLGKDSGPLSDPITGKPYVPLSEAEELRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVIAGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPARGGALLFCTVGILLRKLQSNPSLEGVSHVVVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYPHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPIGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMAPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVSGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLRELRRALGRMVERSLRSELAALPPCVQEEHGQLLALLAELLRGPCGSFDVRKTADD", "length": 1221, "header": "tr|F1N0J0-1|A0ABI0NSA6_BOVIN Computationally mapped isoform of ATP-dependent RNA helicase DHX30 OS=Bos taurus OX=9913 GN=DHX30 PE=3 SV=3 CANONICAL=A0ABI0NSA6-1" }, "locus": { "chromosome": "22", "start_pos": 51925313, "end_pos": 51910472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000030623.5", "url": "https://www.ensembl.org/id/ENSBTAT00000030623.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030598.4", "url": "https://www.ensembl.org/id/ENSBTAP00000030598.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 31, "start_aa": "Thr", "end_pos": 31, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr31", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 41, "start_aa": "Thr", "end_pos": 41, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr41", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSA6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSA6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSA6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSA6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ], "pmid": "" }, { "name": "G-quadruplex RNA binding", "id": "GO:0002151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002151", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSA6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSA6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSA6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSA6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] } ] }, { "uniprot_ac": "A5PJI5", "gene_name": "GET3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A5PJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJI5" } ] } ] }, { "uniprot_ac": "A6QLE5", "gene_name": "NLRP3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A6QLE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLE5" } ] } ] }, { "uniprot_ac": "A6QLJ0", "gene_name": "ERCC2", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A7YSY2" } ] } ] }, { "uniprot_ac": "A7Z019", "gene_name": "SMARCA4", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A7Z019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7Z019" } ] } ] }, { "uniprot_ac": "E1B7X9", "gene_name": "SMARCAD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1B7X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7X9" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B9N7", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] } ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BAN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAN8" } ] } ] }, { "uniprot_ac": "E1BAS6", "gene_name": "SETX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] } ] }, { "uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { 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{ "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { 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"evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": 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"uniprot_ac": "Q0V8B7", "gene_name": "MCM5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0V8B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8B7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q0V8B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8B7" } ] } ] }, { "uniprot_ac": "Q0V8H6", "gene_name": "MOV10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "5.6.2.5", "activity": "n ATP + n H2O + wound RNA = n ADP + n phosphate + unwound RNA.", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "5.6.2.5", "activity": "", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] } ] }, { "uniprot_ac": "Q0VCX2", "gene_name": "HSPA5", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0VCX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCX2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "Q0VCX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCX2" } ] } ] }, { "uniprot_ac": "Q0VD48", "gene_name": "VPS4B", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0VD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD48" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "Q0VD48", "database": "UniProtKB", "url": 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"url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43829:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43829:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00230", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00230", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-432047", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-432047", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29667", "url": "https://www.rhea-db.org/rhea/29667", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29675", "url": "https://www.rhea-db.org/rhea/29675", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NS97", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS97", "database": "UniProtKB", "categories": [ 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"MERVVTRDRVSPLWSLFSLWLKSRTAPDPQPPGPAVPGGASGCVCAHGRRSNRGGGKKAGALLLGSLPLPLGALGGQRLHQPLFPALVPLCLPYLLLFIPVTFHLLPSFASFTLPLFLPSFLFPPFCFFLLIPQVRSSILAIPSLPSLSLLRVSQAPYSWFRLPHLSFLHQLLIQGSSAQAVTSGGTKGNFFTVFLAGSLGIMLAIYVSGNVSGAHLNPAFSLPMCLRGHLPWARFLSYSLVQLLSAFCASGVPYNYPGGSLTVTGPKETASIFATYPAPYLSLSNGFLDQVLGTWKLMGVPAGLEPVVVGLLILADMLSMGANCGFPINPVQDLDPRLFTYVAGWGPEVFRYAGNGWWWVPVVGSLVGAMPGTATYQLLVAKHHPEDSEPSQDLECAQQEASDSGSPAATQLQESKL", "length": 418, "header": "tr|A0ABI0NS97-1|A0ABI0NS97_BOVIN Isoform 1 of Aquaporin 10 OS=Bos taurus OX=9913 GN=AQP10 PE=3 SV=1 CANONICAL=A0ABI0NS97-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NS97-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS97/entry#A0ABI0NS97-1", "sequence": { "sequence": "MERVVTRDRVSPLWSLFSLWLKSRTAPDPQPPGPAVPGGASGCVCAHGRRSNRGGGKKAGALLLGSLPLPLGALGGQRLHQPLFPALVPLCLPYLLLFIPVTFHLLPSFASFTLPLFLPSFLFPPFCFFLLIPQVRSSILAIPSLPSLSLLRVSQAPYSWFRLPHLSFLHQLLIQGSSAQAVTSGGTKGNFFTVFLAGSLGIMLAIYVSGNVSGAHLNPAFSLPMCLRGHLPWARFLSYSLVQLLSAFCASGVPYNYPGGSLTVTGPKETASIFATYPAPYLSLSNGFLDQVLGTWKLMGVPAGLEPVVVGLLILADMLSMGANCGFPINPVQDLDPRLFTYVAGWGPEVFRYAGNGWWWVPVVGSLVGAMPGTATYQLLVAKHHPEDSEPSQDLECAQQEASDSGSPAATQLQESKL", "length": 418, "header": "tr|A0ABI0NS97-1|A0ABI0NS97_BOVIN Isoform 1 of Aquaporin 10 OS=Bos taurus OX=9913 GN=AQP10 PE=3 SV=1 CANONICAL=A0ABI0NS97-1" }, "locus": { "chromosome": "3", "start_pos": 16236934, "end_pos": 16234050, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139056.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139056.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106798.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106798.1" } ] } }, { "isoform_ac": "A0ABI0NUM6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS97/entry#A0ABI0NUM6-1", "sequence": { "sequence": "MERVVTRDRVSPLWSLFSLWLKSRTAPDPQPPGPAVPGGASGCVCAHGRRSNRGGGKKAGALLLGSLPLPLGALGGQRLHQPLFPALVPLCLPYLLLFIPVTFHLLPSFASFTLPLFLPSFLFPPFCFFLLIPQVRSSILAIPSLPSLSLLRVSQAPYSWFRLPHLSFLHQLLIQGSSAQAVTSGGTKGNFFTVFLAGSLGAHLNPAFSLPMCLRGHLPWARFLSYSLVQLLSAFCASGVPYNYPGGSLTVTGPKETASIFATYPAPYLSLSNGFLDQVLGTWKLMGVPAGLEPVVVGLLILADMLSMGANCGFPINPVQDLDPRLFTYVAGWGPEVFSAGNGWWWVPVVGSLVGAMPGTATYQLLVAKHHPEDSEPSQDLECKERSSVSLFSI", "length": 394, "header": "tr|A0ABI0NUM6-1|A0ABI0NUM6_BOVIN Computationally mapped isoform of Aquaporin 10 OS=Bos taurus OX=9913 GN=AQP10 PE=3 SV=1 CANONICAL=A0ABI0NS97-1" }, "locus": { "chromosome": "3", "start_pos": 16236934, "end_pos": 16233181, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148808.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148808.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104200.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104200.1" } ] } }, { "isoform_ac": "F1MNJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS97/entry#F1MNJ1-1", "sequence": { "sequence": "RASTHAQADIRPLRIRSLLARQCLAELLAVFVLMLLIQGSSAQAVTSGGTKGNFFTVFLAGSLGIMLAIYVSGNVSGAHLNPAFSLPMCLRGHLPWARFLSYSLVQLLSAFCASGVPYHALYHDALQNYPGGSLTVTGPKETASIFATYPAPYLSLSNGFLDQVLGTWKLMGVPAGLEPVVVGLLILADMLSMGANCGFPINPVQDLDPRLFTYVAGWGPEVFSAGNGWWWVPVVGSLVGAMPGTATYQLLVAKHHPEDSEPSQDLECAQQEASDSGSPAATQLQESKL", "length": 289, "header": "tr|F1MNJ1-1|A0ABI0NS97_BOVIN Computationally mapped isoform of Aquaporin 10 OS=Bos taurus OX=9913 GN=AQP10 PE=3 SV=5 CANONICAL=A0ABI0NS97-1" }, "locus": { "chromosome": "3", "start_pos": 16237062, "end_pos": 16234050, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006790.8", "url": "https://www.ensembl.org/id/ENSBTAT00000006790.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006790.8", "url": "https://www.ensembl.org/id/ENSBTAP00000006790.8" } ] } 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], "pmid": "" }, { "name": "urea transmembrane transporter activity", "id": "GO:0015204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015204", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS97", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS97" } ], "pmid": "" }, { "name": "channel activity", "id": "GO:0015267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015267", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS97", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29667", "name": "", "equation": "H2O(in) = H2O(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29667", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29667" } ] }, { "id": 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"MLSATPLYGNVHSWMNSERVRMCGISDDRKIPVNDGDASKARLELREENPLNHNVVDATTAHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATTTLGGLGFSSERTPEMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVPTAETLGLDRPASDKQSPLNINGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYGLAQPLYSPVCTNGERFLYLPPPHYVSPHIPSSLASPMRLSTPSASPAIPPLVHCTDKSLPWKMGVSPGNPVDSHSYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPSQPTADTYSEFHKHYARISTSPSVTLSKPYMTVSSEFPAARLCSSKYPKAPEGAESAQPVPGHTRKTAGQDRKDGSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDTSKADHMKKMAPTVLVHSRAGSGLVLSGSEIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKGLPLKNKALDWALPQQRSSSCPRMGATDTVVTNVSGSVSSAGRPASASPAPNATADGSKTSRGSVDTTPSVIQHVGQPPTTPAKHSGSTGSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPYPAPEGIALSPLSLHGKGPVYPHPVLLPSGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDALGLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPSLRNRFSEILEASGTKLHPEVTTDKNLKPSPSWNQGKTVVKSDKLVYVDLLREEPDAKTEANTSKPGFTAESVGQSTEPSKPPAEPALQPHRDFVTLRDELGRINDFHDTYAFKQAPGQSVFNLSKENVPAGTNKENLAMPVSTPFLEPTPGSDGPAVTFGKTQEEPKPFCVGGAPPSVDATPTYTKDGADEAESTDGKVLKPKPSKLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQRAMMRFSELEMKEREGGHPPTKDSEVCKFSPTDWERLKGSQDKKPKSVALEEAIADHNNSERCDYSAGSKHDPFEAPDDKDVSVEKYFLDRQPVSDPSADQVTPDMPNSPTLRADRKRKVSGDSSHTETTVEELPEDPLLKAKRRRVSKDDWPEREMTNSSSNHLEDPHYSELTNLKVCIELTGLHPKKQRHLLHLRERWEQQVSAAESKPGRQGRKEVTQAAQPEVAAQGNNISEEKPGRKRAEAKGNRTWSEESLKSSDSEQGLPVFSGSPPMRSFSSTNLTGRKQSQPSCTAGSRLPAKQQKIKESQKTDVLCTDEEEDCQAASLLQRYPDNSEKPSGKRLCKTKHLIPQEPRRSLPLPGDYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQDQKPLDRLQPLLPVSQTSQLPCSSSPPEATQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRDDDDSSPNSSSNSNVSWDFYGSSVCEPDDESGYDVLANPPGPEDEDDDNDTCSDMFEFEFSESPLLPCYNVQVSVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFNPESKELLDLVEFTNELQTLLGSSMEWLHPSDTGPDDHW", "length": 1748, "header": "tr|G3X8E4-1|A0ABI0NPU5_BOVIN Computationally mapped isoform of BCL6 corepressor OS=Bos taurus OX=9913 GN=BCOR PE=3 SV=3 CANONICAL=A0ABI0NPU5-1" }, "locus": { "chromosome": "X", "start_pos": 103431701, "end_pos": 103408842, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065036.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065036.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055662.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055662.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 908, "start_aa": "Thr", "end_pos": 908, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr908", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:784529", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784529", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPU5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPU5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPU5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPU5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPU5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1079, "end_pos": 1081, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1220, "end_pos": 1222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1236, "end_pos": 1238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1269, "end_pos": 1271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1493, "end_pos": 1495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1566, "end_pos": 1568, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1572, "end_pos": 1574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1607, "end_pos": 1609, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" }, { "start_pos": 881, "end_pos": 883, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NPU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPU5" }, { "id": "PF16553", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16553" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BCL-6 corepressor PCGF1 binding", "eco_id": "ECO_0000259", "start_pos": 1611, "end_pos": 1723, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NPU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPU5" }, { "id": "PF15808", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15808" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BCL-6 corepressor non-ankyrin-repeat", "eco_id": "ECO_0000259", "start_pos": 1171, "end_pos": 1383, "start_aa": "Gly", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 908 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1079, "end_pos": 1081 }, { "start_pos": 1220, "end_pos": 1222 }, { "start_pos": 1236, "end_pos": 1238 }, { "start_pos": 1269, "end_pos": 1271 }, { "start_pos": 1493, "end_pos": 1495 }, { "start_pos": 1566, "end_pos": 1568 }, { "start_pos": 1572, "end_pos": 1574 }, { "start_pos": 1607, "end_pos": 1609 }, { "start_pos": 556, "end_pos": 558 }, { "start_pos": 575, "end_pos": 577 }, { "start_pos": 820, "end_pos": 822 }, { "start_pos": 881, "end_pos": 883 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NPZ3-1", "uniprot_ac": "A0ABI0NPZ3", "uniprot_id": "A0ABI0NPZ3_BOVIN", "mass": { "chemical_mass": 38430.0, "monoisotopic_mass": 38430.0 }, "refseq": {}, "gene_names": [ { "name": "DCPS", "type": "recommended", "evidence": [ { "id": "A0ABI0NPZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3" } ] } ], "protein_names": [ { "name": "m7GpppX diphosphatase", "type": "recommended", "evidence": [ { "id": "A0ABI0NPZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3/entry#names_and_taxonomy" } ] }, { "name": "3.6.1.59", "type": "synonym", "evidence": [ { "id": "A0ABI0NPZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3#function" }, { "database": "UniProtKB", "id": "PIRNR028973", "url": "https://www.uniprot.org/uniprotkb/PIRNR028973#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DCPS", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3", "locus": { "chromosome": "29", "start_pos": 29691817, "end_pos": 29649549, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002879", "url": "https://www.ensembl.org/id/ENSBTAG00000002879" } ] } } ], "crossref": [ { "id": "ENSBTAG00000002879", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002879", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR008594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036265", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036265", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G5E535", "url": "https://www.orthodb.org/?gene=G5E535", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12978", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12978", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12978:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12978:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-429958", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-429958", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "65388", "url": "https://www.rhea-db.org/rhea/65388", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NPZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E535", "url": "https://www.uniprot.org/uniprotkb/G5E535", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E535-1", "url": "https://www.uniprot.org/uniprotkb/G5E535-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELAHQQSKRKRELDAEEAEASSTEGEEAGVGNGTSAPVRLPFSGFRVKKVLRESARDKIIFLHGKVNEASGDGDGEDAVVILEKTPFQVDQVAQLLKGSPELQLQFSNDVYSTYHLFPPRQLSDVKTTVVYPATEKHLQKYLRQDLHLVRETGSDYRNVTLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIKSLRDLTAEHLPLLRNILREGQEAILRRYQVAADRLRVYLHYLPSYYHLHVHFTALGFEAPGAGVERAHLLAEVIDNLEQDPEHYRRRTLTFALRADDPLLALLQEAQRS", "length": 337, "header": "tr|A0ABI0NPZ3-1|A0ABI0NPZ3_BOVIN Isoform 1 of m7GpppX diphosphatase OS=Bos taurus OX=9913 GN=DCPS PE=3 SV=1 CANONICAL=A0ABI0NPZ3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NPZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3/entry#A0ABI0NPZ3-1", "sequence": { "sequence": "MAELAHQQSKRKRELDAEEAEASSTEGEEAGVGNGTSAPVRLPFSGFRVKKVLRESARDKIIFLHGKVNEASGDGDGEDAVVILEKTPFQVDQVAQLLKGSPELQLQFSNDVYSTYHLFPPRQLSDVKTTVVYPATEKHLQKYLRQDLHLVRETGSDYRNVTLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIKSLRDLTAEHLPLLRNILREGQEAILRRYQVAADRLRVYLHYLPSYYHLHVHFTALGFEAPGAGVERAHLLAEVIDNLEQDPEHYRRRTLTFALRADDPLLALLQEAQRS", "length": 337, "header": "tr|A0ABI0NPZ3-1|A0ABI0NPZ3_BOVIN Isoform 1 of m7GpppX diphosphatase OS=Bos taurus OX=9913 GN=DCPS PE=3 SV=1 CANONICAL=A0ABI0NPZ3-1" }, "locus": { "chromosome": "29", "start_pos": 29689605, "end_pos": 29649035, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147106.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147106.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104158.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104158.1" } ] } }, { "isoform_ac": "G5E535-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3/entry#G5E535-1", "sequence": { "sequence": "MLVKVKVLVVQPCPTLCDPMGCIPLGSSLQGVLQARILEWVAIPFSRDGTHLSYIAGGFFTVNEASGDGDGEDAVVILEKTPFQVDQVAQLLKGSPELQLQFSNDVYSTYHLFPPRQLSDVKTTVVYPATEKHLQKYLRQDLHLVRETGSDYRNVTLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIKSLRDLTAEHLPLLRNILREGQEAILRRYQVAADRLRVYLHYLPSYYHLHVHFTALGFEAPGAGVERAHLLAEVIDNLEQDPEHYRRRTLTFALRADDPLLALLQEAQRS", "length": 331, "header": "tr|G5E535-1|A0ABI0NPZ3_BOVIN Computationally mapped isoform of m7GpppX diphosphatase OS=Bos taurus OX=9913 GN=DCPS PE=3 SV=2 CANONICAL=A0ABI0NPZ3-1" }, "locus": { "chromosome": "29", "start_pos": 29689605, "end_pos": 29649571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003732.8", "url": "https://www.ensembl.org/id/ENSBTAT00000003732.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003732.7", "url": "https://www.ensembl.org/id/ENSBTAP00000003732.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-429958", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-429958", "resource": "Reactome", "description": "mRNA decay by 3' to 5' exoribonuclease" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "deadenylation-dependent decapping of nuclear-transcribed mRNA", "id": "GO:0000290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000290", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA 7-methylguanosine cap binding", "id": "GO:0000340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000340", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3" } ], "pmid": "" }, { "name": "5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity", "id": "GO:0140932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140932", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "65388", "name": "", "equation": "a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + N(7)-methyl-GMP + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A2VE79-1", "Q8MJJ7-1", "A0ABI0NPZ3-1" ], "evidence": [ { "id": "65388", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/65388" } ] }, { "id": "R-BTA-429961", "name": "DCPS scavenges the 7-methylguanosine cap of mRNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-429926" ], "output_participant_list": [ "R-ALL-429925", "R-ALL-430042" ], "enzyme_list": [ "A0ABI0NPZ3-1" ], "evidence": [ { "id": "R-BTA-429961", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-429961" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-429925", "participant_name": "oligoribonucleotide with a 5'-diphosphate [cytosol]", "crossref": [ { "id": "33697", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-429926", "participant_name": "capped oligoribonucleotide [cytosol]", "crossref": [ { "id": "33699", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-430042", "participant_name": "7MGMP [cytosol]", "crossref": [ { "id": "17825", "database": "ChEBI", "url": "" }, { "id": "ZINC000004096273", "database": "ZINC", "url": "" }, { "id": "HMDB0059612", "database": "HMDB Metabolite", "url": "" }, { "id": "C03998", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0ABI0NPZ3", "gene_name": "DCPS", "activity": [ { "ec_number": "3.6.1.59", "activity": "a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = N(7)-methyl-GMP + a 5'-end diphospho-ribonucleoside in mRNA + 2 H(+).", "evidence": [ { "id": "A0ABI0NPZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3" } ] }, { "ec_number": "3.6.1.59", "activity": "", "evidence": [ { "id": "A0ABI0NPZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ3" } ] } ] }, { "uniprot_ac": "A2VE79", "gene_name": "NUDT3", "activity": [ { "ec_number": "3.6.1.59", "activity": "a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = N(7)-methyl-GMP + a 5'-end diphospho-ribonucleoside in mRNA + 2 H(+).", "evidence": [ { "id": "A2VE79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VE79" } ] }, { "ec_number": "3.6.1.52", "activity": "6-diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+).", "evidence": [ { "id": "A2VE79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VE79" } ] }, { "ec_number": "3.6.1.62", "activity": "a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = N(7)-methyl-GDP + a 5'-end phospho-ribonucleoside in mRNA + 2 H(+).", "evidence": [ { "id": "A2VE79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VE79" } ] }, { "ec_number": "3.6.1.10", "activity": "[phosphate](n+1) + n H2O = (n+1) phosphate + n H(+).", "evidence": [ { "id": "A2VE79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VE79" } ] }, { "ec_number": "3.6.1.61", "activity": "P(1),P(6)-bis(5'-adenosyl) hexaphosphate + H2O = 2 ATP + 2 H(+).", "evidence": [ { "id": "A2VE79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VE79" } ] }, { "ec_number": "3.6.1.52", "activity": "", "evidence": [ { "id": "A2VE79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VE79" } ] } ] }, { "uniprot_ac": "Q8MJJ7", "gene_name": "DCPS", "activity": [ { "ec_number": "3.6.1.59", "activity": "a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = N(7)-methyl-GMP + a 5'-end diphospho-ribonucleoside in mRNA + 2 H(+).", "evidence": [ { "id": "Q8MJJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MJJ7" } ] }, { "ec_number": "3.6.1.59", "activity": "", "evidence": [ { "id": "Q8MJJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MJJ7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.1.59", "ec_name": "a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = N(7)-methyl-GMP + a 5'-end diphospho-ribonucleoside in mRNA + 2 H(+).", "evidence": [ { "id": "3.6.1.59", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.59" }, { "id": "3.6.1.59", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.1.59" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 34, "end_pos": 36 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NPN8-1", "uniprot_ac": "A0ABI0NPN8", "uniprot_id": "A0ABI0NPN8_BOVIN", "mass": { "chemical_mass": 69229.0, "monoisotopic_mass": 69229.0 }, "refseq": {}, "gene_names": [ { "name": "RELB", "type": "recommended", "evidence": [ { "id": "A0ABI0NPN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ] } ], "protein_names": [ { "name": "Transcription factor RelB", "type": "recommended", "evidence": [ { "id": "A0ABI0NPN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RELB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8", "locus": { "chromosome": "18", "start_pos": 52724621, "end_pos": 52695683, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038428", "url": "https://www.ensembl.org/id/ENSBTAG00000038428" } ] } } ], "crossref": [ { "id": "ENSBTAG00000038428", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038428", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01177", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01177", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07886", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07886", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "522670", "url": "https://www.ncbi.nlm.nih.gov/gene/522670", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032399", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032399", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:522670", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522670", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1MBB0", "url": "https://www.orthodb.org/?gene=F1MBB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24169", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24169", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24169:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24169:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00554", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00554", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16180", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16180", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5607761", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5607761", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5621575", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5621575", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5676590", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5676590", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SU85", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SU85-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYG3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYG3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPN8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MBB0", "url": "https://www.uniprot.org/uniprotkb/F1MBB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MBB0-1", "url": "https://www.uniprot.org/uniprotkb/F1MBB0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNAQAGGAGEFRRPAPARRPPGPARRPPQPRAPRVQPGLRPQPLRRSPDPRSSARPCHLAALPARVCVFWSGLASGPSVPTGWAMPSRRVARSSAAPELGPLGSADLSSLSLAVSRTTEIIDEYIKENGFGLEGAQPGPEGLPRLVSRGAASLSTVTLGPAAPPPPATPPPWGCTLGRLVPPAAGAGPRPHLVITEQPKQRGMRFRYECEGRSAGSILGESSTEASKTLPAIELRDCGGLREVEVTACLVWKDWPHRVHPHSLVGKDCTDGVCRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAGSLKNHQEVDMNVVRICFQASYRDQQGQMRRMDPVLSEPVYDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKEDISVVFSRASWEGRADFSQADVHRQIAIVFKTPPYEDLEIVEPVTVNVFLQRLTDGVCSEPLPFTYLPRDHDSYGVDKKRKRGLPDVLGELNSSDPHGIESKRRRKKPVFLDQFLPSHGSGPYLPPSVLLPDTDFYPGTVSLPSLEPPGGPDLLDDSFPYDPAAPTLLTMLDMLPPAPPLTSAVAGNGGAGAAVGEPPGPEPLTLDSYQAPGPGDGGTASLVGSNMFPNQYREAGFGGGLLSPGPEAT", "length": 644, "header": "tr|A0ABI0NPN8-1|A0ABI0NPN8_BOVIN Isoform 1 of Transcription factor RelB OS=Bos taurus OX=9913 GN=RELB PE=4 SV=1 CANONICAL=A0ABI0NPN8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SU85-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8/entry#A0AAA9SU85-1", "sequence": { "sequence": "MVQIGGPGRWRNQYNTPKRAGLEIIDEYIKENGFGLEGAQPGPEGLPRLVSRGAASLSTVTLGPAAPPPPATPPPWGCTLGRLVPPAAGAGPRPHLVITEQPKQRGMRFRYECEGRSAGSILGESSTEASKTLPAIELRDCGGLREVEVTACLVWKDWPHRVHPHSLVGKDCTDGVCRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAGSLKNHQEVDMNVVRICFQASYRDQQGQMRRMDPVLSEPVYDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKEDISVVFSRASWEGRADFSQADVHRQIAIVFKTPPYEDLEIVEPVTVNVFLQRLTDGVCSEPLPFTYLPRDHDSYGVDKKRKRGLPDVLGELNSSDPHGIESKRRRKKPVFLDQFLPSHGSGPYLPPSVLLPDTDFYPGTVSLPSLEPPGGPDLLDDSFPYDPAAPTLLTMLDMLPPAPPLTSAVAGNGGAGAAVGEPPGPEPLTLDSYQAPGPGDGGTASLVGSNMFPNQYREAGFGGGLLSPGPEAT", "length": 548, "header": "tr|A0AAA9SU85-1|A0ABI0NPN8_BOVIN Computationally mapped isoform of Transcription factor RelB OS=Bos taurus OX=9913 GN=RELB PE=4 SV=1 CANONICAL=A0ABI0NPN8-1" }, "locus": { "chromosome": "18", "start_pos": 52723742, "end_pos": 52701495, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114322.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114322.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088895.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088895.1" } ] } }, { "isoform_ac": "A0AAA9SYG3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8/entry#A0AAA9SYG3-1", "sequence": { "sequence": "MPSRRVARSSAAPELGPLGSADLSSLSLAVSRTTDELEIIDEYIKENGFGLEGAQPGPEGLPRLVSRGAASLSTVTLGPAAPPPPATPPPWGCTLGRLVPPAAGAGPRPHLVITEQPKQRGMRFRYECEGRSAGSILGESSTEASKTLPAIELRDCGGLREVEVTACLVWKDWPHRVHPHSLVGKDCTDGVCRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAGSLKNHQEVDMNVVRICFQASYRDQQGQMRRMDPVLSEPVYDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKEDISVVFSRASWEGRADFSQADVHRQIAIVFKTPPYEDLEIVEPVTVNVFLQRLTDGVCSEPLPFTYLPRDHDSYGVDKKRKRGLPDVLGELNSSDPHGIESKRRRKKPVFLDQFLPSHGSGPYLPPSVLLPDTDFYPGTVSLPSLEPPGGPDLLDDSFPYDPAAPTLLTMLDMLPPAPPLTSAVAGNGGAGAAVGEPPGPEPLTLDSYQAPGPGDGGTASLVGSNMFPNQYREAGFGGGLLSPGPEAT", "length": 563, "header": "tr|A0AAA9SYG3-1|A0ABI0NPN8_BOVIN Computationally mapped isoform of Transcription factor RelB OS=Bos taurus OX=9913 GN=RELB PE=4 SV=2 CANONICAL=A0ABI0NPN8-1" }, "locus": { "chromosome": "18", "start_pos": 52723742, "end_pos": 52695941, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106554.2", "url": "https://www.ensembl.org/id/ENSBTAT00000106554.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089291.2", "url": "https://www.ensembl.org/id/ENSBTAP00000089291.2" } ] } }, { "isoform_ac": "A0ABI0NPN8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8/entry#A0ABI0NPN8-1", "sequence": { "sequence": "MNAQAGGAGEFRRPAPARRPPGPARRPPQPRAPRVQPGLRPQPLRRSPDPRSSARPCHLAALPARVCVFWSGLASGPSVPTGWAMPSRRVARSSAAPELGPLGSADLSSLSLAVSRTTEIIDEYIKENGFGLEGAQPGPEGLPRLVSRGAASLSTVTLGPAAPPPPATPPPWGCTLGRLVPPAAGAGPRPHLVITEQPKQRGMRFRYECEGRSAGSILGESSTEASKTLPAIELRDCGGLREVEVTACLVWKDWPHRVHPHSLVGKDCTDGVCRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAGSLKNHQEVDMNVVRICFQASYRDQQGQMRRMDPVLSEPVYDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKEDISVVFSRASWEGRADFSQADVHRQIAIVFKTPPYEDLEIVEPVTVNVFLQRLTDGVCSEPLPFTYLPRDHDSYGVDKKRKRGLPDVLGELNSSDPHGIESKRRRKKPVFLDQFLPSHGSGPYLPPSVLLPDTDFYPGTVSLPSLEPPGGPDLLDDSFPYDPAAPTLLTMLDMLPPAPPLTSAVAGNGGAGAAVGEPPGPEPLTLDSYQAPGPGDGGTASLVGSNMFPNQYREAGFGGGLLSPGPEAT", "length": 644, "header": "tr|A0ABI0NPN8-1|A0ABI0NPN8_BOVIN Isoform 1 of Transcription factor RelB OS=Bos taurus OX=9913 GN=RELB PE=4 SV=1 CANONICAL=A0ABI0NPN8-1" }, "locus": { "chromosome": "18", "start_pos": 52723742, "end_pos": 52695689, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148731.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148731.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105080.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105080.1" } ] } }, { "isoform_ac": "F1MBB0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8/entry#F1MBB0-1", "sequence": { "sequence": "MNAQAGGAGEFRRPAPARRPPGPARRPPQPRAPRVQPGLRPQPLRRSPDPRSSARPCHLAALPARVCVFWSGLASGPSVPTGWAMPSRRVARSSAAPELGPLEIIDEYIKENGFGLEGAQPGPEGLPRLVSRGAASLSTVTLGPAAPPPPATPPPWGCTLGRLVPPAAGAGPRPHLVITEQPKQRGMRFRYECEGRSAGSILGESSTEASKTLPAIELRDCGGLREVEVTACLVWKDWPHRVHPHSLVGKDCTDGVCRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIERKIQLGIDPYNAGSLKNHQEVDMNVVRICFQASYRDQQGQMRRMDPVLSEPVYDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKEDISVVFSRASWEGRADFSQADVHRQIAIVFKTPPYEDLEIVEPVTVNVFLQRLTDGVCSEPLPFTYLPRDHDSYGVDKKRKRGLPDVLGELNSSDPHGIESKRRRKKPVFLDQFLPSHGSGPYLPPSVLLPDTDFYPGTVSLPSLEPPGGPDLLDDSFPYDPAAPTLLTMLDMLPPAPPLTSAVAGNGGAGAAVGEPPGPEPLTLDSYQAPGPGDGGTASLVGSNMFPNQYREAGFGGGLLSPGPEAT", "length": 628, "header": "tr|F1MBB0-1|A0ABI0NPN8_BOVIN Computationally mapped isoform of Transcription factor RelB OS=Bos taurus OX=9913 GN=RELB PE=4 SV=4 CANONICAL=A0ABI0NPN8-1" }, "locus": { "chromosome": "18", "start_pos": 52723742, "end_pos": 52695689, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055496.5", "url": "https://www.ensembl.org/id/ENSBTAT00000055496.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049624.4", "url": "https://www.ensembl.org/id/ENSBTAP00000049624.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 168, "start_aa": "Thr", "end_pos": 168, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr168", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:522670", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522670", "resource": "KEGG Pathway" }, { "id": "R-BTA-5607761", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5607761", "resource": "Reactome", "description": "Dectin-1 mediated noncanonical NF-kB signaling" }, { "id": "R-BTA-5621575", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5621575", "resource": "Reactome", "description": "CD209 (DC-SIGN) signaling" }, { "id": "R-BTA-5676590", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5676590", "resource": "Reactome", "description": "NIK-->noncanonical NF-kB signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" }, { "name": "lymphocyte differentiation", "id": "GO:0030098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030098", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" }, { "name": "response to cytokine", "id": "GO:0034097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034097", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" }, { "name": "canonical NF-kappaB signal transduction", "id": "GO:0007249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007249", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" }, { "name": "non-canonical NF-kappaB signal transduction", "id": "GO:0038061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038061", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPN8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NPN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPN8" }, { "id": "PS50254", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50254" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RHD", "eco_id": "ECO_0000259", "start_pos": 187, "end_pos": 364, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 168 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 364, "end_pos": 366 }, { "start_pos": 488, "end_pos": 490 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NND2-1", "uniprot_ac": "A0ABI0NND2", "uniprot_id": "A0ABI0NND2_BOVIN", "mass": { "chemical_mass": 160012.0, "monoisotopic_mass": 160012.0 }, "refseq": { "ac": "XP_005217296", "name": "ras GTPase-activating protein nGAP isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217296" }, "gene_names": [ { "name": "RASAL2", "type": "recommended", "evidence": [ { "id": "A0ABI0NND2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2" } ] }, { "name": "RASAL2", "type": "synonym", "evidence": [ { "id": "XP_005217296", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217296" } ] } ], "protein_names": [ { "name": "RAS protein activator like 2", "type": "synonym", "evidence": [ { "id": "A0ABI0NND2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2/entry#names_and_taxonomy" } ] }, { "name": "ras GTPase-activating protein nGAP isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005217296", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217296" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NND2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RASAL2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2", "locus": { "chromosome": "16", "start_pos": 59879926, "end_pos": 59736218, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015537", "url": "https://www.ensembl.org/id/ENSBTAG00000015537" } ] } } ], "crossref": [ { "id": "cd04013", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04013", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05136", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05136", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540692", "url": "https://www.ncbi.nlm.nih.gov/gene/540692", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540692", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540692", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LXQ3", "url": "https://www.orthodb.org/?gene=A0A3Q1LXQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M8V3", "url": "https://www.orthodb.org/?gene=A0A3Q1M8V3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1B800", "url": "https://www.orthodb.org/?gene=E1B800", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10194", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10194", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10194:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10194:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00616", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00616", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25321", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25321", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9696273", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696273", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005217296", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217296", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LXQ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LXQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M8V3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8V3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M8V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8V3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0C3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0C3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0C3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0C3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NND2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NND2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NV16", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NV16-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZJ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B800", "url": "https://www.uniprot.org/uniprotkb/E1B800", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B800-1", "url": "https://www.uniprot.org/uniprotkb/E1B800-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESWKMSIFKRQTSPCPPSYRRSLSEPAYTHSEIGTSLKSYPWRGPVKSKRKKNEQAVSSLGKPLGAYRWQTHHSLRLKGDKKEQLENNKGDLDEPPQQAVLPKMVGDNISSSGNEVLGTSMEKQNLVNTQSLRVPFSRSLSEPEPGSSVRFVRRWPTSVGSVESDQQGYFIRGIFSTLSNGFSRMLSLKGGSTSEPVREDVKGPPTHRLSCGQSPYTDTTTWERKYCILTDSQLVLLNKEKEIPVDGGQEQQADSTKGRCLRRTVSVPSEGQFPEYPPEGATKLEVPAERSPRRRSISGTTTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRNTDDRSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELLDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDEKESSLPNGRSISLMDLQETHAAQAEHPSVILDVPMRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGSLQPLSFQNPVYHLSNPIPAMPKASVDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTMPDRHIPLALPRQNSTGQTQLRKMDPAGLGARAKAPPSLPHSASLRSTGSMSVASAALVAEPLQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNQDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNGISPTNPTKLSITENGEFKNSSC", "length": 1420, "header": "tr|A0ABI0NND2-1|A0ABI0NND2_BOVIN Isoform 1 of RAS protein activator like 2 OS=Bos taurus OX=9913 GN=RASAL2 PE=4 SV=1 CANONICAL=A0ABI0NND2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LXQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2/entry#A0A3Q1LXQ3-1", "sequence": { "sequence": "MGSSCDKEVPAERSPRRRSISGTTTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRNTDDRSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELLDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDEKESSLPNGRSISLMDLQETHAAQAEHPSVILDVPMRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGSLQPLSFQNPVYHLSNPIPAMPKASVDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTMPDRHIPLALPRQNSTGQTQLRKMDPAGLGARAKAPPSLPHSASLRSTGSMSVASAALVAEPLQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNQDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQVINGDEIMQTGKTDRVAGFGQHQTDECADPGEGTVQHAGPKWHLPHQPHQAFHHGEW", "length": 1138, "header": "tr|A0A3Q1LXQ3-1|A0ABI0NND2_BOVIN Computationally mapped isoform of RAS protein activator like 2 OS=Bos taurus OX=9913 GN=RASAL2 PE=4 SV=2 CANONICAL=A0ABI0NND2-1" }, "locus": { "chromosome": "16", "start_pos": 59878900, "end_pos": 59781564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086983.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086983.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062288.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062288.2" } ] } }, { "isoform_ac": "A0A3Q1M8V3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2/entry#A0A3Q1M8V3-1", "sequence": { "sequence": "MELSLSSGGAAEALSWPEMFPGLESDSPLPPEELDAVVPVSGAMAGGMLDRILLESVCQQQSWVRVYDVKGPPTHRLSCGQSPYTDTTTWERKYCILTDSQLVLLNKEKEIPVDGGQEQQADSTKGRCLRRTVSVPSEGQFPEYPPEGATKLEVPAERSPRRRSISGTTTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRNTDDRSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELLDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDEKESSLPNGRSISLMDLQETHAAQAEHPSVILDVPMRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGSLQPLSFQNPVYHLSNPIPAMPKASVDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTMPDRHIPLALPRQNSTGQTQLRKMDPAGLGARAKAPPSLPHSASLRSTGSMSVASAALVAEPLQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNQDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQENTQITKIQMKQFIPLIKRDWFYMDS", "length": 1279, "header": "tr|A0A3Q1M8V3-1|A0ABI0NND2_BOVIN Computationally mapped isoform of RAS protein activator like 2 OS=Bos taurus OX=9913 GN=RASAL2 PE=4 SV=3 CANONICAL=A0ABI0NND2-1" }, "locus": { "chromosome": "16", "start_pos": 59879551, "end_pos": 59487477, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079900.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079900.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070371.3", "url": "https://www.ensembl.org/id/ENSBTAP00000070371.3" } ] } }, { "isoform_ac": "A0AAA9S0C3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2/entry#A0AAA9S0C3-1", "sequence": { "sequence": "MLATPRNFTECRPQRCQQKGPHADGVSQGPLHLRNPTLWTLRIPHPSKYQSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELLDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDEKESSLPNGRSISLMDLQETHAAQAEHPSVILDVPMRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGSLQPLSFQNPVYHLSNPIPAMPKASVDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTMPDRHIPLALPRQNSTGQTQLRKMDPAGLGARAKAPPSLPHSASLRSTGSMSVASAALVAEPLQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNQDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNGISPTNPTKLSITENGEFKNSSC", "length": 1105, "header": "tr|A0AAA9S0C3-1|A0ABI0NND2_BOVIN Computationally mapped isoform of RAS protein activator like 2 OS=Bos taurus OX=9913 GN=RASAL2 PE=4 SV=1 CANONICAL=A0ABI0NND2-1" }, "locus": { "chromosome": "16", "start_pos": 59878922, "end_pos": 59736335, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088619.2", "url": "https://www.ensembl.org/id/ENSBTAT00000088619.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079289.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079289.1" } ] } }, { "isoform_ac": "A0ABI0NND2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2/entry#A0ABI0NND2-1", "sequence": { "sequence": "MESWKMSIFKRQTSPCPPSYRRSLSEPAYTHSEIGTSLKSYPWRGPVKSKRKKNEQAVSSLGKPLGAYRWQTHHSLRLKGDKKEQLENNKGDLDEPPQQAVLPKMVGDNISSSGNEVLGTSMEKQNLVNTQSLRVPFSRSLSEPEPGSSVRFVRRWPTSVGSVESDQQGYFIRGIFSTLSNGFSRMLSLKGGSTSEPVREDVKGPPTHRLSCGQSPYTDTTTWERKYCILTDSQLVLLNKEKEIPVDGGQEQQADSTKGRCLRRTVSVPSEGQFPEYPPEGATKLEVPAERSPRRRSISGTTTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRNTDDRSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELLDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDEKESSLPNGRSISLMDLQETHAAQAEHPSVILDVPMRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGSLQPLSFQNPVYHLSNPIPAMPKASVDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTMPDRHIPLALPRQNSTGQTQLRKMDPAGLGARAKAPPSLPHSASLRSTGSMSVASAALVAEPLQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNQDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNGISPTNPTKLSITENGEFKNSSC", "length": 1420, "header": "tr|A0ABI0NND2-1|A0ABI0NND2_BOVIN Isoform 1 of RAS protein activator like 2 OS=Bos taurus OX=9913 GN=RASAL2 PE=4 SV=1 CANONICAL=A0ABI0NND2-1" }, "locus": { "chromosome": "16", "start_pos": 59878922, "end_pos": 59630147, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147480.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147480.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107275.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107275.1" } ] } }, { "isoform_ac": "A0ABI0NV16-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2/entry#A0ABI0NV16-1", "sequence": { "sequence": "MDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRNTDDSSGGCEVQDEGPGRFSVWSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELLDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDEKESSLPNGRSISLMDLQETHAAQAEHPSVILDVPMRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGSLQPLSFQNPVYHLSNPIPAMPKASVDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTMPDRHIPLALPRQNSTGQTQLRKMDPAGLGARAKAPPSLPHSASLRSTGSMSVASAALVAEPLQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNQDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNGISPTNPTKLSITENGEFKNSSC", "length": 1128, "header": "tr|A0ABI0NV16-1|A0ABI0NV16_BOVIN Computationally mapped isoform of RAS protein activator like 2 OS=Bos taurus OX=9913 GN=RASAL2 PE=4 SV=1 CANONICAL=A0ABI0NND2-1" }, "locus": { "chromosome": "16", "start_pos": 59878922, "end_pos": 59782449, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140620.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140620.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107728.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107728.1" } ] } }, { "isoform_ac": "A0ABI0NZJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2/entry#A0ABI0NZJ1-1", "sequence": { "sequence": "MELSLSSGGAAEALSWPEMFPGLESDSPLPPEELDAVVPVSGAMAGGMLDRILLESVCQQQSWVRVYDVKGPPTHRLSCGQSPYTDTTTWERKYCILTDSQLVLLNKEKEIPVDGGQEQQADSTKGRCLRRTVSVPSEGQFPEYPPEGATKLEVPAERSPRRRSISGTTTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRNTDDRSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELLDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDEKESSLPNGRSISLMDLQETHAAQAEHPSVILDVPMRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGSLQPLSFQNPVYHLSNPIPAMPKASVDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTMPDRHIPLALPRQNSTGQTQLRKMDPAGLGARAKAPPSLPHSASLRSTGSMSVASAALVAEPLQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNQDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNGISPTNPTKLSITENGEFKNSSC", "length": 1287, "header": "tr|A0ABI0NZJ1-1|A0ABI0NZJ1_BOVIN Computationally mapped isoform of RAS protein activator like 2 OS=Bos taurus OX=9913 GN=RASAL2 PE=4 SV=1 CANONICAL=A0ABI0NND2-1" }, "locus": { "chromosome": "16", "start_pos": 59878922, "end_pos": 59487477, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141024.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141024.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106666.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106666.1" } ] } }, { "isoform_ac": "E1B800-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2/entry#E1B800-1", "sequence": { "sequence": "MELSLSSGGAAEALSWPEMFPGLESDSPLPPEELDAVVPVSGAMAGGMLDRILLESVCQQQSWVRVYDVKGPPTHRLSCGQSPYTDTTTWERKYCILTDSQLVLLNKEKEIPVDGGQEQQADSTKGRCLRRTVSVPSEGQFPEYPPEGATKLEVPAERSPRRRSISGTTTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRNTDDRSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELLDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDEKESSLPNGRSISLMDLQETHAAQAEHPSVILDVPMRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGSLQPLSFQNPVYHLSNPIPAMPKASVDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTMPDRHIPLALPRQNSTGQTQLRKMDPAGLGARAKAPPSLPHSASLRSTGSMSVASAALVAEPLQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNQDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQVINGDEIMQTGKTDRVAGFGQHQTDECADPGEGTVQHAGPKWHLPHQPHQAFHHGEW", "length": 1290, "header": "tr|E1B800-1|A0ABI0NND2_BOVIN Computationally mapped isoform of RAS protein activator like 2 OS=Bos taurus OX=9913 GN=RASAL2 PE=4 SV=5 CANONICAL=A0ABI0NND2-1" }, "locus": { "chromosome": "16", "start_pos": 59878900, "end_pos": 59487477, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020658.8", "url": "https://www.ensembl.org/id/ENSBTAT00000020658.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020658.8", "url": "https://www.ensembl.org/id/ENSBTAP00000020658.8" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540692", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540692", "resource": "KEGG Pathway" }, { "id": "R-BTA-9696264", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696264", "resource": "Reactome", "description": "RND3 GTPase cycle" }, { "id": "R-BTA-9696273", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696273", "resource": "Reactome", "description": "RND1 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NND2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NND2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1087, "end_pos": 1089, "annotation": "n_glycosylation_sequon" }, { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1109, "end_pos": 1111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1144, "end_pos": 1146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1195, "end_pos": 1197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1417, "end_pos": 1419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 914, "end_pos": 916, "annotation": "n_glycosylation_sequon" }, { "start_pos": 918, "end_pos": 920, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NND2", "database": "UniProtKB", "url": 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"UniProtKB", "id": "A0ABI0NT36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT36" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT36" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT36" } ], "pmid": "" }, { "name": "epidermal growth factor receptor signaling pathway", "id": "GO:0007173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007173", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT36" } ], "pmid": "" }, { "name": "positive regulation of cell 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", 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"evidence": [ { "id": "A0ABI0NQB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQB8/entry#names_and_taxonomy" } ] }, { "name": "transmembrane channel-like protein 6 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024835537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024835537" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQB8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQB8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMC6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQB8", "locus": { "chromosome": "19", "start_pos": 54048552, "end_pos": 54025415, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018661", "url": "https://www.ensembl.org/id/ENSBTAG00000018661" } ] } } ], "crossref": [ { "id": "ENSBTAG00000018661", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018661", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "505575", "url": "https://www.ncbi.nlm.nih.gov/gene/505575", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MA74", "url": "https://www.orthodb.org/?gene=A0A3Q1MA74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MFD8", "url": "https://www.orthodb.org/?gene=A0A3Q1MFD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23302:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024835537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024835537", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MA74", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MA74-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MFD8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MFD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQB8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQB8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQSPAFVLNVLETPEDPEGSQEPSPYDESEVHDSFHQLIQEQSRWVAEEGLELQQRQPETGALGASGSDHETMLGPEGAPVYSMATLRILASMPSRTIGRSRGAIISQYYSRTVKLRRRAGRPQLRDMGRSARPSLRLYDLELDSAVLEEEEKRGLLVKELQGLTAAQRDHMLRGMPLSLAEKRGLREESRPPRGKHRAQWHRGLLSCCDQLRDSCVLASHNLGLALLSGLQALMPWHYALKRIGGRFGSSVLSYFLFLKTLLAFNTLLLPPLLAFIVGVQAAFPPAPTGPVPAFTGLELLTGGGYFTHSVMYYGYYSNATLNQPCASPLDGSQCTPEAGSLPYSMPLAYLFTLGAAFFITCITLVYSMSRSFGESYRVGSTSGVHAITVFCSWDYKVTQRWATRLQHDNIRTQLKELLAEWQSRQHRRSACGQLRRVAVLGLVWLLCLGTTLGCTLAVYTFSELMIKSPVSAEREAVLLLLPLVVCLLNLGGPYLFRILAALERHDSPVLEVYVAICRNLILKMVTLGILCYHWLGRRVGTLKDQCWENFVGQELYRLMVMDFIFTLLDTLLGELVWRLFSEKQLKRKGKPEFDIAGNVLELIYGQTLTWLGVLFSPLLPAMQIIKLLLLFYIKKASLMANCQAPRRPWKASHMSTVFISLLCFPSFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGKVWVRRLEKAGPRVSWLPWIHRYLVEDTFPIYLVSALLLAVIYLNIQVVKGQRKVICLLKEQISNEGEDKIFLINKLQRVYERKERSRSSREAGQSQELSVLTSGANLGPVFSVKCGRGP", "length": 822, "header": "tr|A0ABI0NQB8-1|A0ABI0NQB8_BOVIN Isoform 1 of Transmembrane channel-like protein OS=Bos taurus OX=9913 GN=TMC6 PE=3 SV=1 CANONICAL=A0ABI0NQB8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MA74-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQB8/entry#A0A3Q1MA74-1", "sequence": { "sequence": "MSQSPAFVLNVLETPEDPEGQEPSPYDESEVHDSFHQLIQEQSRWVAEEGLELQQRQPETGALGASGSDHETMLGPEGAPVYSMATLRILASMPSRTIGRSRGAIISQYYSRTVKLRRRAGRPQLRDMGRSARPSLRLYDLELDSAVLEEEEKRGLLVKELQGLTAAQRDHMLRGMPLSLAEKRGLREESRPPRGKHRAQWHRGLLSCCDQLRDSCVLASHNLGLALLSGLQALMPWHYALKRIGGRFGSSVLSYFLFLKTLLAFNTLLLPPLLAFIVGVQAAFPPAPTGPVPAFTGLELLTGGGYFTHSVMYYGYYSNATLNQPCASPLDGSQCTPEAGSLPYSMPLAYLFTLGAAFFITCITLVYSMSRSFGESYRVGSTSGVHAITVFCSWDYKVTQRWATRLQHDNIRTQLKELLAEWQSRQHRRSACGQLRRVAVLGLVWLLCLGTTLGCTLAVYTFSELMIKSPVSAEREAVLLLLPLVVCLLNLGGPYLFRILAALERHDSPVLEVYVAICRNLILKMVTLGILCYHWLGRRVGTLKDQCWENFVGQELYRLMVMDFIFTLLDTLLGELVWRLFSEKQLKRKGKPEFDIAGNVLELIYGQTLTWLGVLFSPLLPAMQIIKLLLLFYIKKASLMANCQAPRRPWKASHMSTVFISLLCFPSFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGKVWVRRLEKAGPRVSWLPWIHRYLVEDTFPIYLVSALLLAVIYLNIQVVKGQRKVICLLKEQISNEGEDKIFLINKLQRVYERKERSRSSREAGQSQELSVLTSGANLGPVFSVKCGRGP", "length": 821, "header": "tr|A0A3Q1MA74-1|A0ABI0NQB8_BOVIN Computationally mapped isoform of Transmembrane channel-like protein OS=Bos taurus OX=9913 GN=TMC6 PE=3 SV=2 CANONICAL=A0ABI0NQB8-1" }, "locus": { "chromosome": "19", "start_pos": 54047548, "end_pos": 54028383, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074476.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074476.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070902.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070902.2" } ] } }, { "isoform_ac": "A0A3Q1MFD8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQB8/entry#A0A3Q1MFD8-1", "sequence": { "sequence": "MSQSPAFVLNVLETPEDPEGQEPSPYDESEVHDSFHQLIQEQSRWVAEEGLELQQRQPETGALGASGSDHETMLGPEGAPVYSMATLRILASMPSRTIGRSRGAIISQYYSRTVKLRRRAGRPQLRDMGRSARPSLRLYDLELDSAVLEEEEKRGLLVKELQGLTAAQRDHMLRGMPLSLAEKRGLREESRPPRGKHRAQWHRGLLSCCDQLRDSCVLASHNLGLALLSGLQALMPWHYALKRIGGRFGSSVLSYFLFLKTLLAFNTLLLPPLLAFIVGVQAAFPPAPTGPVPAFTGLELLTGGGYFTHSVMYYGYYSNATLNQPCASPLDGSQCTPEAGSLPYSMPLAYLFTLGAAFFITCITLVYSMSRSFGESYRVGSTSGVHAITVFCSWDYKVTQRWATRLQHDNIRTQLKELLAEWQSRQHRRSACGQLRRVAVLGLVWLLCLGTTLGCTLAVYTFSELMIKSPVSAEREAVLLLLPLVVCLLNLGGPYLFRILAALERHDSPVLEVYVAICRNLILKMVTLGILCYHWLGRRVGTLKDQCWENFVGQELYRLMVMDFIFTLLDTLLGELVWRLFSEKQLKRKGKPEFDIAGNVLELIYGQTLTWLGVLFSPLLPAMQIIKLLLLFYIKKASLMANCQAPRRPWKASHMSTVFISLLCFPSFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGKVWVRRLEKAGPRVSWLPWIHRYLVEDTFPIYLVSALLLAVIYLNIQVVKGQRKVICLLKEQISNEGEDKIFLINKLQRVYERKERSRAGRTEEAVTPPALLTDGWDAQ", "length": 810, "header": "tr|A0A3Q1MFD8-1|A0ABI0NQB8_BOVIN Computationally mapped isoform of Transmembrane channel-like protein OS=Bos taurus OX=9913 GN=TMC6 PE=3 SV=2 CANONICAL=A0ABI0NQB8-1" }, "locus": { "chromosome": "19", "start_pos": 54043203, "end_pos": 54028383, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075955.3", "url": "https://www.ensembl.org/id/ENSBTAT00000075955.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069241.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069241.2" } ] } }, { "isoform_ac": "A0ABI0NQB8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQB8/entry#A0ABI0NQB8-1", "sequence": { "sequence": "MSQSPAFVLNVLETPEDPEGSQEPSPYDESEVHDSFHQLIQEQSRWVAEEGLELQQRQPETGALGASGSDHETMLGPEGAPVYSMATLRILASMPSRTIGRSRGAIISQYYSRTVKLRRRAGRPQLRDMGRSARPSLRLYDLELDSAVLEEEEKRGLLVKELQGLTAAQRDHMLRGMPLSLAEKRGLREESRPPRGKHRAQWHRGLLSCCDQLRDSCVLASHNLGLALLSGLQALMPWHYALKRIGGRFGSSVLSYFLFLKTLLAFNTLLLPPLLAFIVGVQAAFPPAPTGPVPAFTGLELLTGGGYFTHSVMYYGYYSNATLNQPCASPLDGSQCTPEAGSLPYSMPLAYLFTLGAAFFITCITLVYSMSRSFGESYRVGSTSGVHAITVFCSWDYKVTQRWATRLQHDNIRTQLKELLAEWQSRQHRRSACGQLRRVAVLGLVWLLCLGTTLGCTLAVYTFSELMIKSPVSAEREAVLLLLPLVVCLLNLGGPYLFRILAALERHDSPVLEVYVAICRNLILKMVTLGILCYHWLGRRVGTLKDQCWENFVGQELYRLMVMDFIFTLLDTLLGELVWRLFSEKQLKRKGKPEFDIAGNVLELIYGQTLTWLGVLFSPLLPAMQIIKLLLLFYIKKASLMANCQAPRRPWKASHMSTVFISLLCFPSFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGKVWVRRLEKAGPRVSWLPWIHRYLVEDTFPIYLVSALLLAVIYLNIQVVKGQRKVICLLKEQISNEGEDKIFLINKLQRVYERKERSRSSREAGQSQELSVLTSGANLGPVFSVKCGRGP", "length": 822, "header": "tr|A0ABI0NQB8-1|A0ABI0NQB8_BOVIN Isoform 1 of Transmembrane channel-like protein OS=Bos taurus OX=9913 GN=TMC6 PE=3 SV=1 CANONICAL=A0ABI0NQB8-1" }, "locus": { "chromosome": "19", "start_pos": 54047548, "end_pos": 54028383, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136926.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136926.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104398.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104398.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 290, "start_aa": "Thr", "end_pos": 290, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr290", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQB8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NQB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQB8" }, { "id": "PF07810", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07810" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TMC", "eco_id": "ECO_0000259", "start_pos": 548, "end_pos": 654, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 290 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 320, "end_pos": 322 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NRI4-1", "uniprot_ac": "A0ABI0NRI4", "uniprot_id": "A0ABI0NRI4_BOVIN", "mass": { "chemical_mass": 85441.0, "monoisotopic_mass": 85441.0 }, "refseq": { "ac": "XP_005219895", "name": "tigger transposable element-derived protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219895" }, "gene_names": [ { "name": "LOC101903649", "type": "recommended", "evidence": [ { "id": "A0ABI0NRI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI4" } ] }, { "name": "LOC101903649", "type": "synonym", "evidence": [ { "id": "XP_005219895", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219895" } ] } ], "protein_names": [ { "name": "Tigger transposable element-derived protein 1-like", "type": "recommended", "evidence": [ { "id": "A0ABI0NRI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI4/entry#names_and_taxonomy" } ] }, { "name": "tigger transposable element-derived protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005219895", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219895" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRI4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC101903649", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI4", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000049866", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000049866", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101903649", "url": "https://www.ncbi.nlm.nih.gov/gene/101903649", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ARTYIAK", "url": "https://omabrowser.org/oma/group/ARTYIAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR19303", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19303", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19303:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19303:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03221", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03221", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04218", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04218", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005219895", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219895", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MBS2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MBS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRI4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRI4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0R2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0R2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0R2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0R2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAADPAPFGQEELVIIKVEEDEDVPWDPEPFSEPQPHTPLPALGWDPRLCFRSFRYEEAAGPREALVQLRELCRQWLRPEVHSKEQMLELLVLEQFLGVLPPDTRVWVESQCPESGEEAVALVADLAQMFQETALVQAPPEDQQPGDLAEPAKPFSDGAQYLYFKPRMSGSKRKSSGDVAGTAKKRHAITMETKVKIIERVERGEKMTDVARSFNLNRSTIGTIVKNKDKILEHVKSAVSMMSTIISKRRGKAMEEMEKLLSVWLQDQHQRRAPLNIMLIQEKAKSLYEDLKKKYGEESDGPSFNASCGWFYRFKARANLHSVKVSDEAVSADVAAAREFPEILREIIDEGAYLPEQVFNVDETGLYWKRMPDRSYISKEEKLMPGYKAAKDRLTLLFGGNASGDMKLKPLLVYHSESPKALRNIAKGSLPVVWKSNPKAWVTQAIFQDWFFHHFIPEVEIYCLEKDIPFNILLLLDSAPGHPLFMDDFHPNVKVVRLPPDTAPLIQPMDQGVISTFKKYYLRHTFRQAVKASEESGTTLRQFWKDYNIYKAIKNIDFAWREVTAGTMNGVWKNLCPQFVHDFREFEKVDEESREVFSNLVTLSEKLELDLQEDDFIELLAMQHEELTNEDLMELEAQRKDEERQEEEERGEELKRFTMQDMARGFALFEEALFVFEAQDPNVERYTKVEAAVQNAIQCYRVVYDEKKRATAQTSLDRLLKREMELNPARSQNLCLEVRPE", "length": 741, "header": "tr|A0ABI0NRI4-1|A0ABI0NRI4_BOVIN Isoform 1 of Tigger transposable element-derived protein 1-like OS=Bos taurus OX=9913 GN=LOC101903649 PE=4 SV=1 CANONICAL=A0ABI0NRI4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MBS2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI4/entry#A0A3Q1MBS2-1", "sequence": { "sequence": "MCLHVPSRKLVHVSGVHCHMCAASTWGCVFCVLHSTVVQYLYFKPRMSGSKRKSSGDVAGTAKKRHAITMETKVKIIERVERGEKMTDVARSFNLNRSTIGTIVKNKDKILEHVKSAVSMMSTIISKRRGKAMEEMEKLLSVWLQDQHQRRAPLNIMLIQEKAKSLYEDLKKKYGEESDGPSFNASCGWFYRFKARANLHSVKVSDEAVSADVAAAREFPEILREIIDEGAYLPEQVFNVDETGLYWKRMPDRSYISKEEKLMPGYKAAKDRLTLLFGGNASGDMKLKPLLVYHSESPKALRNIAKGSLPVVWKSNPKAWVTQAIFQDWFFHHFIPEVEIYCLEKDIPFNILLLLDSAPGHPLFMDDFHPNVKVVRLPPDTAPLIQPMDQGVISTFKKYYLRHTFRQAVKASEESGTTLRQFWKDYNIYKAIKNIDFAWREVTAGTMNGVWKNLCPQFVHDFREFEKVDEESREVFSNLVTLSEKLELDLQEDDFIELLAMQHEELTNEDLMELEAQRKDEERQEEEERGEELKRFTMQDMARGFALFEEALFVFEAQDPNVERYTKVEAAVQNAIQCYRVVYDEKKRATAQTSLDRLLKREMELNPARSQNLCLEVRPE", "length": 620, "header": "tr|A0A3Q1MBS2-1|A0ABI0NRI4_BOVIN Computationally mapped isoform of Tigger transposable element-derived protein 1-like OS=Bos taurus OX=9913 GN=LOC101903649 PE=4 SV=1 CANONICAL=A0ABI0NRI4-1" }, "locus": { "chromosome": "18", "start_pos": 65813820, "end_pos": 65811961, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098438.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098438.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101516.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101516.1" } ] } }, { "isoform_ac": "A0ABI0NRI4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI4/entry#A0ABI0NRI4-1", "sequence": { "sequence": "MAADPAPFGQEELVIIKVEEDEDVPWDPEPFSEPQPHTPLPALGWDPRLCFRSFRYEEAAGPREALVQLRELCRQWLRPEVHSKEQMLELLVLEQFLGVLPPDTRVWVESQCPESGEEAVALVADLAQMFQETALVQAPPEDQQPGDLAEPAKPFSDGAQYLYFKPRMSGSKRKSSGDVAGTAKKRHAITMETKVKIIERVERGEKMTDVARSFNLNRSTIGTIVKNKDKILEHVKSAVSMMSTIISKRRGKAMEEMEKLLSVWLQDQHQRRAPLNIMLIQEKAKSLYEDLKKKYGEESDGPSFNASCGWFYRFKARANLHSVKVSDEAVSADVAAAREFPEILREIIDEGAYLPEQVFNVDETGLYWKRMPDRSYISKEEKLMPGYKAAKDRLTLLFGGNASGDMKLKPLLVYHSESPKALRNIAKGSLPVVWKSNPKAWVTQAIFQDWFFHHFIPEVEIYCLEKDIPFNILLLLDSAPGHPLFMDDFHPNVKVVRLPPDTAPLIQPMDQGVISTFKKYYLRHTFRQAVKASEESGTTLRQFWKDYNIYKAIKNIDFAWREVTAGTMNGVWKNLCPQFVHDFREFEKVDEESREVFSNLVTLSEKLELDLQEDDFIELLAMQHEELTNEDLMELEAQRKDEERQEEEERGEELKRFTMQDMARGFALFEEALFVFEAQDPNVERYTKVEAAVQNAIQCYRVVYDEKKRATAQTSLDRLLKREMELNPARSQNLCLEVRPE", "length": 741, "header": "tr|A0ABI0NRI4-1|A0ABI0NRI4_BOVIN Isoform 1 of Tigger transposable element-derived protein 1-like OS=Bos taurus OX=9913 GN=LOC101903649 PE=4 SV=1 CANONICAL=A0ABI0NRI4-1" }, "locus": { "chromosome": "18", "start_pos": 65813820, "end_pos": 65809431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147851.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147851.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105183.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105183.1" } ] } }, { "isoform_ac": "A0ABI0P0R2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI4/entry#A0ABI0P0R2-1", "sequence": { "sequence": "MAADPAPFGQEELVIIKVEEDEDVPWDPEPFSEPQPHTPLPALGWDPRLCFRSFRYEEAAGPREALVQLRELCRQWLRPEVHSKEQMLELLVLEQFLGVLPPDTRVWVESQCPESGEEAVALVADLAQMFQETALVQAPPEDQQPGDLAEPAKPFSDGAQPRMSGSKRKSSGDVAGTAKKRHAITMETKVKIIERVERGEKMTDVARSFNLNRSTIGTIVKNKDKILEHVKSAVSMMSTIISKRRGKAMEEMEKLLSVWLQDQHQRRAPLNIMLIQEKAKSLYEDLKKKYGEESDGPSFNASCGWFYRFKARANLHSVKVSDEAVSADVAAAREFPEILREIIDEGAYLPEQVFNVDETGLYWKRMPDRSYISKEEKLMPGYKAAKDRLTLLFGGNASGDMKLKPLLVYHSESPKALRNIAKGSLPVVWKSNPKAWVTQAIFQDWFFHHFIPEVEIYCLEKDIPFNILLLLDSAPGHPLFMDDFHPNVKVVRLPPDTAPLIQPMDQGVISTFKKYYLRHTFRQAVKASEESGTTLRQFWKDYNIYKAIKNIDFAWREVTAGTMNGVWKNLCPQFVHDFREFEKVDEESREVFSNLVTLSEKLELDLQEDDFIELLAMQHEELTNEDLMELEAQRKDEERQEEEERGEELKRFTMQDMARGFALFEEALFVFEAQDPNVERYTKVEAAVQNAIQCYRVVYDEKKRATAQTSLDRLLKREMELNPARSQNLCLEVRPE", "length": 736, "header": "tr|A0ABI0P0R2-1|A0ABI0P0R2_BOVIN Computationally mapped isoform of Tigger transposable element-derived protein 1-like OS=Bos taurus OX=9913 GN=LOC101903649 PE=4 SV=1 CANONICAL=A0ABI0NRI4-1" }, "locus": { "chromosome": "18", 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"A0ABI0NRI4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NRI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRI4" }, { "id": "PRU00320", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00320" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "H-T-H motif", "eco_id": "ECO_0000256", "start_pos": 207, "end_pos": 227, "start_aa": "Met", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": 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"url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 127, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 434, "end_pos": 436 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NNY0-1", "uniprot_ac": "A0ABI0NNY0", "uniprot_id": "A0ABI0NNY0_BOVIN", "mass": { "chemical_mass": 252914.0, "monoisotopic_mass": 252914.0 }, "refseq": { "ac": "NP_001178965", "name": "protein ELYS", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178965" }, "gene_names": [ { "name": "AHCTF1", "type": "recommended", "evidence": [ { "id": "A0ABI0NNY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNY0" } ] }, { "name": "AHCTF1", "type": "synonym", "evidence": [ { "id": "NP_001178965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178965" } ] } ], "protein_names": [ { "name": "AT-hook containing transcription factor 1", "type": "synonym", "evidence": [ { "id": "A0ABI0NNY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNY0/entry#names_and_taxonomy" } ] }, { "name": "protein ELYS", "type": "synonym", "evidence": [ { "id": "NP_001178965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178965" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNY0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNY0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AHCTF1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNY0", "locus": { "chromosome": "16", "start_pos": 30506647, "end_pos": 30410579, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013949", "url": "https://www.ensembl.org/id/ENSBTAG00000013949" } ] } } ], "crossref": [ { "id": "ENSBTAG00000013949", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013949", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "504716", "url": "https://www.ncbi.nlm.nih.gov/gene/504716", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:504716", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504716", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR21583", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21583", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21583:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21583:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13934", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13934", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16687", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16687", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9615933", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9615933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001178965", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178965", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMV9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNY0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNY0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZI5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZI5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZI5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRDLTAQVTSGLLQFPEVTIQALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPIVLAVKEFSWQKRTGLLIGLEEVEGSVLCLYDLGLSRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSCSQNEVEASDLEVITGIPAEVPRIRENVMREGRHLCFQLVSPSGTAVSTLSYINRTNQLAVGFSDGYLALWNMKSMKKEYYTQLEGGRVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLTGGMFPLRGQTGNTKLLGCQSIEKFRSHGDREESMNEALSPDTSVSVFTWQVNIYGQGKPSIYLGLFDINRWYHAQMPDSLRSGEYLHNCSYFALWSLDAVVSRTSPHYILDILVHERSLSRGVPPSYPPPEQFFNPSTYNFDATCLLNSGVVHITCTGFQKETLTFLKKSGPSLNEVIPDGYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGCIKRWITEEQPNSAANLRFVLEWSWNKVVFTKEEFDRLCTPLFDGSCRFIDPQTIQSLQQCHLLLSNLSTVLSCFAAEAHDITERGLTDLSNKYMVTQLICQYAQVVLWFSHSGLLPEGLDDAVQLSRLCYNYPVIQNYYTSRRQKCERSSRGKWNPDCLMIDGMVSQLGDRVEKLWKRDEGGTGKYPPTSLHALLDIYLLDNITEASKHSVTIYLLLDIMYSFPNKTDTSIESFPTAFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPVSWQHSKIIEAFMSQGEHRQALRYIQTMKPTVSSGRDVILHLTVLLFNRCMVEAWTLLRQHSNRLNIEELLKHTYEVCQEMGLMEDLLKLPFTDTEQECLVRFLQSSASVQNHEFLLVHHLQRANYISALKLNQTLKINLMNDRDPRLRERSVTRNSIIDQYGKILPRVQRKLAIERAKPYHLSASSVFREVSRPKPLSAVPKQAVTGTVLTRSTFINNVLSKIGEVWASNEPENSISVYNSPKVEEPSPVAYSLPDPELPEAFVGTPITKASQRISRLLDLVVHPVPQPSQCLELIQQSPTRSPWSLASSSLPVSSQLKGSRQNASRASELHLLETPLVVKKAKTLAMSVTSSGFAEFTPQSILRSGLRTTPLASPSLSPGRSLSPPLRLKETRISFMEEGVTTKWTAATVDDSKAKTFITASLHKCGAPAETEWLKNKDKTTSFPLDSPEEEHQEMDVRSQDTTSQSLEKLDVSVENSNTSTRSDQTTLEYQDAPLPEDFEDILIASKSVSSSTELVANLTEQTEKNSDKDTFEPGVTPPEPEKQMGTLEDAEAKDGLVVEGVLSELNHLSPIQGVEASLCVPSVREEELLSLKSTVPVLDEGLVSVEAYTSAVTAGNNKSTPEVPGDSGRSGPVTSESPVVSEHRLDQEVELNLKEDHEIEVDVLKASVDLPEEKTPISDDPPDTQEIHVIEHEKLEGQDSGQEARNLSFNELYPSGTLKLQYNFDTIEQQFCDLPDNKDSAECDIAEVDGEHFVAQSNFTLILEGEEGEVETDDSAASDVLAKAANAATEEKHVCSEESENHRHVADLPSVIMSDQKSQRVETLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIQENIPLISQKVKCSTKLANFTTKTVQETSTETINVSEVNDMISSRTRKRGRVQNLNVKSAQQEEPAAVATPEMLGLSVTKKTRKTKEIAGALESASSDDKGVSHNQQIPQNAITPRRGRRKKDVNQDTLENANSVEQELQVTPGRELRRLKSSQLLEAATEESSFRKEVKLSSATKRTPRRTKSVENRESVEVINDLKVSKVAGPSRSTRKLRSTHLEASESVGYKQEGESAEQQLPIQRGKRVKKKEVSALDVTEDSKLDSSQLTIQADFGTPATPRKRGRPRKINPSEDVESKAVTEAGSLKKREGLSIQRRSTRNTPAKSENTDVGKPTLEESVFMPNEEVAAVMSSKKQLTKRTENQSQKRSLRSIPEKCIDEETAHTEPDAQEERLLATVALTKSSRSTRTRSTKAILLPDLSEPKNESLLFSPPVSKIPRKEKAKKIEAPAQLQELVSDLPSQFVSSPPALRTRRKNPLNTSKHTDGLEDDGQTTETVGKQQVKRIRTAKTKQASKNTEKESWSPPPVEIKLISPLASPVDGVKSKPRKTAEVTGKTVGRSRKKLSSFPKQVLRRKML", "length": 2276, "header": "tr|A0ABI0NNY0-1|A0ABI0NNY0_BOVIN Isoform 1 of AT-hook containing transcription factor 1 OS=Bos taurus OX=9913 GN=AHCTF1 PE=4 SV=1 CANONICAL=A0ABI0NNY0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MMV9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNY0/entry#A0A3Q1MMV9-1", "sequence": { "sequence": "MAAERRSGSMRDLTAQVTSGLLQFPEVTIQALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPIVLAVKEFSWQKRTGLLIGLEEVEGSVLCLYDLGLSRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSCSQNEVEASDLEVITGIPAEVPRIRENVMREGRHLCFQLVSPSGTAVSTLSYINRTNQLAVGFSDGYLALWNMKSMKKEYYTQLEGGRVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLTGGMFPLRGQTGNTKLLGCQSIEKFRSHGDREESMNEALSPDTSVSVFTWQVNIYGQGKPSIYLGLFDINRWYHAQMPDSLRSGEYLHNCSYFALWSLDAVVSRTSPHYILDILVHERSLSRGVPPSYPPPEQFFNPSTYNFDATCLLNSGVVHITCTGFQKETLTFLKKSGPSLNEVIPDGYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGCIKRWITEEQPNSAANLRFVLEWSWNKVVFTKEEFDRLCTPLFDGSCRFIDPQTIQSLQQCHLLLSNLSTVLSCFAAEAHDITERGLTDLSNKYMVTQLICQYAQVVLWFSHSGLLPEGLDDAVQLSRLCYNYPVIQNYYTSRRQKCERSSRGKWNPDCLMIDGMVSQLGDRVEKLWKRDEGGTGKYPPTSLHALLDIYLLDNITEASKHSVTIYLLLDIMYSFPNKTDTSIESFPTAFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPVSWQHSKIIEAFMSQGEHRQALRYIQTMKPTVSSGRDVILHLTVLLFNRCMVEAWTLLRQHSNRLNIEELLKHTYEVCQEMGLMEDLLKLPFTDTEQECLVRFLQSSASVQNHEFLLVHHLQRANYISALKLNQTLKINLMNDRDPRLRERSVTRNSIIDQYGKILPRVQRKLAIERAKPYHLSASSVFREVSRPKPLSAVPKQAVTGTVLTRSTFINNVLSKIGEVWASNEPENSISVYNSPKVEEPSPVAYSLPDPELPEAFVGTPITKASQRISRLLDLVVHPVPQPSQCLELIQQSPTRSPWSLASSSLPVSSQLKGSRQNASRASELHLLETPLVVKKAKTLAMSVTSSGFAEFTPQSILRSGLRTTPLASPSLSPGRSLSPPLRLKETRISFMEEGVTTKWTAATVDDSKAKTFITASLHKCGAPAETEWLKNKDKTTSFPLDSPEEEHQEMDVRSQDTTSQSLEKLDVSVENSNTSTRSDQTTLEYQDAPLPEDFEDILIASKSVSSSTELVANLTEQTEKNSDKDTFEPGVTPPEPEKQMGTLEDAEAKDGLVVEGVLSELNHLSPIQGVEASLCVPSVREEELLSLKSTVPVLDEGLVSVEAYTSAVTAGNNKSTPEVPGDSGRSGPVTSESPVVSEHRLDQEVELNLKEDHEIEVDVLKASVDLPEEKTPISDDPPDTQEIHVIEHEKLEGQDSGQEARNLSFNELYPSGTLKLQYNFDTIEQQFCDLPDNKDSAECDIAEVDGEHFVAQSNFTLILEGEEGEVETDDSAASDVLAKAANAATEEKHVCSEESENHRHVADLPSVIMSDQKSQRVETLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIQENIPLISQKVKCSTKLANFTTKTVQETSTETINVSEVNDMISSRTRKRGRVQNLNVKSAQQEEPAAVATPEMLGLSVTKKTRKTKEIAGALESASSDDKGVSHNQQIPQNAITPRRGRRKKDVNQDTLENANSVEQELQVTPGRELRRLKSSQLLEAATEESSFRKEVKLSSATKRTPRRTKSVENRESVEVINDLKVSKVAGPSRSTRKLRSTHLEASESVGYKQEGESAEQQLPIQRGKRVKKKEVSALDVTEDSKLDSSQLTIQADFGTPATPRKRGRPRKINPSEDVESKAVTEAGSLKKREGLSIQRRSTRNTPAKSENTDVGKPTLEESVFMPNEEVAAVMSSKKQLTKRTENQSQKRSLRSIPEKCIDEETAHTEPDAQEERLLATVALTKSSRSTRTRSTKAILLPDLSEPKNESLLFSPPVSKIPRKEKAKKIEAPAQLQELVSDLPSQFVSSPPALRTRRKNPLNTSKHTDGLEDDGQTTETVGKQQVKRIRTAKTKQASKNTEKESWSPPPVEIKLISPLASPVDGVKSKPRKTAEVTGKTVGRSRKKLSSFPKQVLRRKML", "length": 2285, "header": "tr|A0A3Q1MMV9-1|A0ABI0NNY0_BOVIN Computationally mapped isoform of AT-hook containing transcription factor 1 OS=Bos taurus OX=9913 GN=AHCTF1 PE=4 SV=3 CANONICAL=A0ABI0NNY0-1" }, "locus": { "chromosome": "16", "start_pos": 30505118, "end_pos": 30411047, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077376.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077376.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073178.3", "url": "https://www.ensembl.org/id/ENSBTAP00000073178.3" } ] } }, { "isoform_ac": "A0ABI0NNY0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNY0/entry#A0ABI0NNY0-1", "sequence": { "sequence": "MRDLTAQVTSGLLQFPEVTIQALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPIVLAVKEFSWQKRTGLLIGLEEVEGSVLCLYDLGLSRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSCSQNEVEASDLEVITGIPAEVPRIRENVMREGRHLCFQLVSPSGTAVSTLSYINRTNQLAVGFSDGYLALWNMKSMKKEYYTQLEGGRVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLTGGMFPLRGQTGNTKLLGCQSIEKFRSHGDREESMNEALSPDTSVSVFTWQVNIYGQGKPSIYLGLFDINRWYHAQMPDSLRSGEYLHNCSYFALWSLDAVVSRTSPHYILDILVHERSLSRGVPPSYPPPEQFFNPSTYNFDATCLLNSGVVHITCTGFQKETLTFLKKSGPSLNEVIPDGYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGCIKRWITEEQPNSAANLRFVLEWSWNKVVFTKEEFDRLCTPLFDGSCRFIDPQTIQSLQQCHLLLSNLSTVLSCFAAEAHDITERGLTDLSNKYMVTQLICQYAQVVLWFSHSGLLPEGLDDAVQLSRLCYNYPVIQNYYTSRRQKCERSSRGKWNPDCLMIDGMVSQLGDRVEKLWKRDEGGTGKYPPTSLHALLDIYLLDNITEASKHSVTIYLLLDIMYSFPNKTDTSIESFPTAFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPVSWQHSKIIEAFMSQGEHRQALRYIQTMKPTVSSGRDVILHLTVLLFNRCMVEAWTLLRQHSNRLNIEELLKHTYEVCQEMGLMEDLLKLPFTDTEQECLVRFLQSSASVQNHEFLLVHHLQRANYISALKLNQTLKINLMNDRDPRLRERSVTRNSIIDQYGKILPRVQRKLAIERAKPYHLSASSVFREVSRPKPLSAVPKQAVTGTVLTRSTFINNVLSKIGEVWASNEPENSISVYNSPKVEEPSPVAYSLPDPELPEAFVGTPITKASQRISRLLDLVVHPVPQPSQCLELIQQSPTRSPWSLASSSLPVSSQLKGSRQNASRASELHLLETPLVVKKAKTLAMSVTSSGFAEFTPQSILRSGLRTTPLASPSLSPGRSLSPPLRLKETRISFMEEGVTTKWTAATVDDSKAKTFITASLHKCGAPAETEWLKNKDKTTSFPLDSPEEEHQEMDVRSQDTTSQSLEKLDVSVENSNTSTRSDQTTLEYQDAPLPEDFEDILIASKSVSSSTELVANLTEQTEKNSDKDTFEPGVTPPEPEKQMGTLEDAEAKDGLVVEGVLSELNHLSPIQGVEASLCVPSVREEELLSLKSTVPVLDEGLVSVEAYTSAVTAGNNKSTPEVPGDSGRSGPVTSESPVVSEHRLDQEVELNLKEDHEIEVDVLKASVDLPEEKTPISDDPPDTQEIHVIEHEKLEGQDSGQEARNLSFNELYPSGTLKLQYNFDTIEQQFCDLPDNKDSAECDIAEVDGEHFVAQSNFTLILEGEEGEVETDDSAASDVLAKAANAATEEKHVCSEESENHRHVADLPSVIMSDQKSQRVETLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIQENIPLISQKVKCSTKLANFTTKTVQETSTETINVSEVNDMISSRTRKRGRVQNLNVKSAQQEEPAAVATPEMLGLSVTKKTRKTKEIAGALESASSDDKGVSHNQQIPQNAITPRRGRRKKDVNQDTLENANSVEQELQVTPGRELRRLKSSQLLEAATEESSFRKEVKLSSATKRTPRRTKSVENRESVEVINDLKVSKVAGPSRSTRKLRSTHLEASESVGYKQEGESAEQQLPIQRGKRVKKKEVSALDVTEDSKLDSSQLTIQADFGTPATPRKRGRPRKINPSEDVESKAVTEAGSLKKREGLSIQRRSTRNTPAKSENTDVGKPTLEESVFMPNEEVAAVMSSKKQLTKRTENQSQKRSLRSIPEKCIDEETAHTEPDAQEERLLATVALTKSSRSTRTRSTKAILLPDLSEPKNESLLFSPPVSKIPRKEKAKKIEAPAQLQELVSDLPSQFVSSPPALRTRRKNPLNTSKHTDGLEDDGQTTETVGKQQVKRIRTAKTKQASKNTEKESWSPPPVEIKLISPLASPVDGVKSKPRKTAEVTGKTVGRSRKKLSSFPKQVLRRKML", 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"VETLASFSPGHPAGTLDLCSVDGCSACCRAWLCGSMRDLTAQVTSGLLQFPEVTIQALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPIVLAVKEFSWQKRTGLLIGLEEVEGSVLCLYDLGLSRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSCSQNEVEASDLEVITGIPAEVPRIRENVMREGRHLCFQLVSPSGTAVSTLSYINRTNQLAVGFSDGYLALWNMKSMKKEYYTQLEGGRVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLTGGMFPLRGQTGNTKLLGCQSIEKFRSHGDREESMNEALSPDTSVSVFTWQVNIYGQGKPSIYLGLFDINRWYHAQMPDSLRSGEYLHNCSYFALWSLDAVVSRTSPHYILDILVHERSLSRGVPPSYPPPEQFFNPSTYNFDATCLLNSGVVHITCTGFQKETLTFLKKSGPSLNEVIPDGYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGCIKRWITEEQPNSAANLRFVLEWSWNKVVFTKEEFDRLCTPLFDGSCRFIDPQTIQSLQQCHLLLSNLSTVLSCFAAEAHDITERGLTDLSNKYMVTQLICQYAQVVLWFSHSGLLPEGLDDAVQLSRLCYNYPVIQNYYTSRRQKCERSSRGKWNPDCLMIDGMVSQLGDRVEKLWKRDEGGTGKYPPTSLHALLDIYLLDNITEASKHSVTIYLLLDIMYSFPNKTDTSIESFPTAFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPVSWQHSKIIEAFMSQGEHRQALRYIQTMKPTVSSGRDVILHLTVLLFNRCMVEAWTLLRQHSNRLNIEELLKHTYEVCQEMGLMEDLLKLPFTDTEQECLVRFLQSSASVQNHEFLLVHHLQRANYISALKLNQTLKINLMNDRDPRLRERSVTRNSIIDQYGKILPRVQRKLAIERAKPYHLSASSVFREVSRPKPLSAVPKQAVTGTVLTRSTFINNVLSKIGEVWASNEPENSISVYNSPKVEEPSPVAYSLPDPELPEAFVGTPITKASQRISRLLDLVVHPVPQPSQCLELIQQSPTRSPWSLASSSLPVSSQLKGSRQNASRASELHLLETPLVVKKAKTLAMSVTSSGFAEFTPQSILRSGLRTTPLASPSLSPGRSLSPPLRLKETRISFMEEGVTTKWTAATVDDSKAKTFITASLHKCGAPAETEWLKNKDKTTSFPLDSPEEEHQEMDVRSQDTTSQSLEKLDVSVENSNTSTRSDQTTLEYQDAPLPEDFEDILIASKSVSSSTELVANLTEQTEKNSDKDTFEPGVTPPEPEKQMGTLEDAEAKDGLVVEGVLSELNHLSPIQGVEASLCVPSVREEELLSLKSTVPVLDEGLVSVEAYTSAVTAGNNKSTPEVPGDSGRSGPVTSESPVVSEHRLDQEVELNLKEDHEIEVDVLKASVDLPEEKTPISDDPPDTQEIHVIEHEKLEGQDSGQEARNLSFNELYPSGTLKLQYNFDTIEQQFCDLPDNKDSAECDIAEVDGEHFVAQSNFTLILEGEEGEVETDDSAASDVLAKAANAATEEKHVCSEESENHRHVADLPSVIMSDQKSQRVETLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIQENIPLISQKVKCSTKLANFTTKTVQETSTETINVSEVNDMISSRTRKRGRVQNLNVKSAQQEEPAAVATPEMLGLSVTKKTRKTKEIAGALESASSDDKGVSHNQQIPQNAITPRRGRRKKDVNQDTLENANSVEQELQVTPGRELRRLKSSQLLEAATEESSFRKEVKLSSATKRTPRRTKSVENRESVEVINDLKVSKVAGPSRSTRKLRSTHLEASESVGYKQEGESAEQQLPIQRGKRVKKKEVSALDVTEDSKLDSSQLTIQADFGTPATPRKRGRPRKINPSEDVESKAVTEAGSLKKREGLSIQRRSTRNTPAKSENTDVGKPTLEESVFMPNEEVAAVMSSKKQLTKRTENQSQKRSLRSIPEKCIDEETAHTEPDAQEERLLATVALTKSSRSTRTRSTKAILLPDLSEPKNESLLFSPPVSKIPRKEKAKKIEAPAQLQELVSDLPSQFVSSPPALRTRRKNPLNTSKHTDGLEDDGQTTETVGKQQVKRIRTAKTKQASKNTEKESWSPPPVEIKLISPLASPVDGVKSKPRKTAEVTGKTVGRSRKKLSSFPKQVLRRKML", "length": 2311, "header": "tr|A0ABI0NZI5-1|A0ABI0NZI5_BOVIN Computationally mapped isoform of AT-hook containing transcription factor 1 OS=Bos taurus OX=9913 GN=AHCTF1 PE=4 SV=1 CANONICAL=A0ABI0NNY0-1" }, "locus": { "chromosome": "16", "start_pos": 30505118, "end_pos": 30411167, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148789.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148789.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107105.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107105.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:504716", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504716", "resource": "KEGG Pathway" }, { "id": "R-BTA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-BTA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-BTA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-BTA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-BTA-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-BTA-9615933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9615933", "resource": "Reactome", "description": "Postmitotic nuclear pore complex (NPC) reformation" }, { "id": "R-BTA-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNY0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1163, "end_pos": 1165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1319, "end_pos": 1321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1359, "end_pos": 1361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1459, "end_pos": 1461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1548, "end_pos": 1550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1600, "end_pos": 1602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1721, "end_pos": 1723, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1736, "end_pos": 1738, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2062, "end_pos": 2064, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2124, "end_pos": 2126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2178, "end_pos": 2180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" }, { "start_pos": 971, "end_pos": 973, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NMW2-1", "uniprot_ac": "A0ABI0NMW2", "uniprot_id": "A0ABI0NMW2_BOVIN", "mass": { "chemical_mass": 271415.0, "monoisotopic_mass": 271415.0 }, "refseq": { "ac": "NP_001422124", "name": "NAC-alpha domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422124" }, "gene_names": [ { "name": "NACAD", "type": "recommended", "evidence": [ { "id": "A0ABI0NMW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW2" } ] }, { "name": "NACAD", "type": "synonym", "evidence": [ { "id": "NP_001422124", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422124" } ] } ], "protein_names": [ { "name": "NAC alpha domain containing", "type": "synonym", "evidence": [ { "id": "A0ABI0NMW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW2/entry#names_and_taxonomy" } ] }, { "name": "NAC-alpha domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001422124", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422124" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NACAD", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW2", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000051248", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000051248", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14416", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14416", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "531208", "url": "https://www.ncbi.nlm.nih.gov/gene/531208", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LT39", "url": "https://www.orthodb.org/?gene=A0A3Q1LT39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MNH6", "url": "https://www.orthodb.org/?gene=A0A3Q1MNH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21713", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21713", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01849", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01849", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001422124", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422124", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LT39", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LT39-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJ87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJ87-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMW2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMW2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXZ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGEAARAELLLPEAGGPGPRTDLSCDAAEATTPKGDRLEHCALTSGPSTLALTFLHGKPGARPPPEGASWDAGPGRAPSAWTVQAEGGPSPGPAEVRPTEGPLPASLEPRIVMGEETCQAAPLPRATMPELRDWEGGHANLNPPPEFCSQGDPPVPFPAPDSDSYFTPPSTPTKTASTLLPGPGPHRDAQDAQAELGDSPPASPTGSYITADGDSWASSPSCSLSLQALAEGLDVPSGWGFSPSGSVVDERELPPAGTPDSSSPESSLSADSSSSWGQEGHFFELDFLANDPMIPAYLLPFQGSLIFQVEAVEVTPLPHEEEEVEEEEQEEEQEVPLPRGDLAGEGEDDSTFASSLQSLSDLSITEGVDEAFAFRDDTSAASSDPDSASYTGADDERLYSGEPHAQPATLLQDSPGEAASWGPELALGVSKGEAGQAAKNQEPISEIMRVGPAAAQVSSAMAPHIPQESLDLTGVSPQAQGEEPGSTMGPVPVAPIMSQPLQEGDTATLGPEPWILKREADLNSLQTLKEDTGQGFAAATSPEPQPEVDPAAFPPFQDAGIPWVQESASETSPEPQLEEEELTASSHLLPLVQGSASEASPEPQSEEDLTASLPLKDEGLPLVQGSASEASPELQSEEEDLTASSTPQDAGLPLVQGSASEASPELQSEEKDLTASSTPQDAGLPLVQGSASEASPESQSEEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQESASEVSPEPQSEEDLTASLPLKDESLPLVQGSASKASPEPQSEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQESASEVSPEPQSEEDLTASLPLKDESLPLVQGSASEASPEPQSEDLTASLPLKDEGLPLVQGSASEASPEPQSEEDLTASPPLQDTDLPLVQGSVSEASPEPQSEEDLTASPPLQDAGLPLVQGSASDASPESQSEDLRASLHLQDAGLRLVQGSVSEVSPEPQSEEEDLTASPPLQDAGLPLVQGSASEASPDHQSDLKASPPLQDAGLPLVHGPASEASPEPQSEEEELTASLPLQDTGLHLVQGSAFKASPELQSEEEVTASSPLQDTGLHLVQGSASKASPEPQSEEEELTASPPLQDTGLPLVHGSASEASPELQSEEVTASPPLQDTGLPLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVQGSVSEASTEPQSEEEELTASLHLQDTGFSLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVHGSASEASPELQSEEVTASPPLQDTGLPLVQGSASDASSEPQSEEELTASPPLQDAGLPLVQGSASKVSPEPQSEEEDLTASPPVKDAGLPLVQGSASDASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPLVQGSASDASSEPQSEEEELTASPPLQDAGLPLVQGSASEASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPFVQGSASEASSEPQSEEELTASPPLQDAGLPLVQGSASEASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPFVQGSASEASSEPQSEEELTASPTLQDAGLPLVQGSASKASPELQSEVTASPPLQVAGLPLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVQGSASEASPESQSEEDLTASSPLKDAGLPLVQGSAFEASLEPHSEEEDLTASPPLQDTGLPLVQGSAFKASPEPHSEEEDLTASLPLQDAGLPFVQGSASEASSEPQSEEELTALPTLQDAGLPLVQGSASKASPEPQSEDLTASPPLQDAGLPFVQGSASETSPEPHSEEELTASPPLQDTGLPLVQGSASEASLEPHSEEELTASSPLQDAGLPLVQGSASEASPEPHSEEEELIAFPPQQDAGLPSSQVSATSASPQALMTDTGCTQKTEPTTTAAHRKGRKTLGLRPAPEERDPDHTGGSDSLALDQIHLGGPDLPADARTPLEGDAGPSKPATEIPDTPKPFTAAQGPPKPDSSGEEVAEGILAPEQEACHDICAHGGDGAESSSPPKVALGVEHQGHEALKPVVHGPGVCPTASLEVGQLGPPSPVEEGRATLGHRLPMAVGSEAGLGSCSQSPSRAVPRLGGHCAKDPAPTSPLPLRQPKPVLGPGKGERAQAALGVLGPSPLQPPESPIGGLPSAPQDRIQGPEPPAPGILMEAVPTPLASPAPCPCRGPREDLVEGAEPLGSPSHPPPRPRAQRAVAASSGITNPPGAGQVSLPPHPTLLSPKAAPKRGTHAKDPASRLSPPRQVPPGSGPRSPAGPRGLPATEQQDDGDSLEEDSPRALGSGQHSDSHGESSAELEEQDLPGPQTAQCPAQAPAGSGSEETVAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHRAAAEKFKVPSEPSALVPESAPGPRVRPECEEEEEEEDEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNQSDIVNAIMELTM", "length": 2647, "header": "tr|A0ABI0NMW2-1|A0ABI0NMW2_BOVIN Isoform 1 of NAC alpha domain containing OS=Bos taurus OX=9913 GN=NACAD PE=4 SV=1 CANONICAL=A0ABI0NMW2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LT39-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW2/entry#A0A3Q1LT39-1", "sequence": { "sequence": "MPGEAARAELLLPEAGGPGPRTDLSCDAAEATTPKGDRLEHCALTSGPSTLALTFLHGKPGARPPPEGASWDAGPGRAPSAWTVQAEGGPSPGPAEVRPTEGPLPASLEPRIVMGEETCQAAPLPRATMPELRDWEGGHANLNPPPEFCSQGDPPVPFPAPDSDSYFTPPSTPTKTASTLLPGPGPHRDAQDAQAELGDSPPASPTGSYITADGDSWASSPSCSLSLQALAEGLDVPSGWGFSPSGSVVDERELPPAGTPDSSSPESSLSADSSSSWGQEGHFFELDFLANDPMIPAYLLPFQGSLIFQVEAVEVTPLPHEEEEVEEEEQEEEQEVPLPRGDLAGEGEDDSTFASSLQSLSDLSITEGVDEAFAFRDDTSAASSDPDSASYTGADDERLYSGEPHAQPATLLQDSPGEAASWGPELALGVSKGEAGQAAKNQEPISEIMRVGPAAAQVSSAMAPHIPQESLDLTGVSPQAQGEEPGSTMGPVPVAPIMSQPLQEGDTATLGPEPWILKREADLNSLQTLKEDTGQGFAAATSPEPQPEVDPAAFPPFQDAGIPWVQESASETSPEPQLEEEELTASSHLLPLVQGSASEASPEPQSEEDLTASLPLKDEGLPLVQGSASEASPELQSEEEDLTASSTPQDAGLPLVQGSASEASPELQSEEKDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQESASEVSPEPQSEEDLTASLPLKDESLPLVQGSASKASPEPQSEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQESASEVSPEPQSEEDLTASLPLKDESLPLVQGSASEASPEPQSEEDLTASPPLQDTDLPLVQGSVSEASPEPQSEEDLTASPPLQDAGLPLVQGSASDASPESQSEDLRASLHLQDAGLRLVQGSVSEVSPEPQSEEEDLTASPPLQDAGLPLVQGSASEASPDHQSDLKASPPLQDAGLPLVHGPASEASPEPQSEEEELTASLPLQDTGLHLVQGSAFKASPELQSEEEVTASSPLQDTGLHLVQGSASKASPEPQSEEEELTASPPLQDTGLPLVHGSASEASPELQSEEVTASPPLQDTGLPLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVQGSVSEASTEPQSEEEELTASLHLQDTGFSLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVHGSASEASPELQSEEVTASPPLQDTGLPLVQGSASDASSEPQSEEELTASPPLQDAGLPLVQGSASKVSPEPQSEEEDLTASPPVKDAGLPLVQGSASDASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPLVQGSASDASSEPQSEEEELTASPPLQDAGLPLVQGSASEASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPFVQGSASEASSEPQSEEELTASPPLQDAGLPLVQGSASEASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPFVQGSASEASSEPQSEEELTASPTLQDAGLPLVQGSASKASPELQSEVTASPPLQVAGLPLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVQGSASEASPESQSEEDLTASSPLKDAGLPLVQGSAFEASLEPHSEEEDLTASPPLQDTGLPLVQGSAFKASPEPHSEEEDLTASLPLQDAGLPFVQGSASEASSEPQSEEELTALPTLQDAGLPLVQGSASKASPEPQSEDLTASPPLQDAGLPFVQGSASETSPEPHSEEELTASPPLQDTGLPLVQGSASEASLEPHSEEELTASSPLQDAGLPLVQGSASEASPEPHSEEEELIAFPPQQDAGLPSSQVSATSASPQALMTDTGCTQKTEPTTTAAHRKGRKTLGLRPAPEERDPDHTGGSDSLALDQIHLGGPDLPADARTPLEGDAGPSKPATEIPDTPKPFTAAQGPPKPDSSGEEVAEGILAPEQEACHDICAHGGDGAESSSPPKVALGVEHQGHEALKPVVHGPGVCPTASLEVGQLGPPSPVEEGRATLGHRLPMAVGSEAGLGSCSQSPSRAVPRLGGHCAKDPAPTSPLPLRQPKPVLGPGKGERAQAALGVLGPSPLQPPESPIGGLPSAPQDRIQGPEPPAPGILMEAVPTPLASPAPCPCRGPREDLVEGAEPLGSPSHPPPRPRAQRAVAASSGITNPPGAGQVSLPPHPTLLSPKAAPKRGTHAKDPASRLSPPRQVPPGSGPRSPAGPRGLPATEQQDDGDSLEEDSPRALGSGQHSDSHGESSAELEEQDLPGPQTAQCPAQAPAGSGSEETVAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHRAAAEKFKVPSEPSALVPESAPGPRVRPECEEEEEEEDEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNQSDIVNAIMELTM", "length": 2554, "header": "tr|A0A3Q1LT39-1|A0ABI0NMW2_BOVIN Computationally mapped isoform of NAC alpha domain containing OS=Bos taurus OX=9913 GN=NACAD PE=4 SV=2 CANONICAL=A0ABI0NMW2-1" }, "locus": { "chromosome": "4", "start_pos": 76548689, "end_pos": 76537740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079886.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079886.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060471.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060471.2" } ] } }, { "isoform_ac": "A0A3Q1MNH6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW2/entry#A0A3Q1MNH6-1", "sequence": { "sequence": "MPGEAARAELLLPEAGGPGPRTDLSCDAAEATTPKGDRLEHCALTSGPSTLALTFLHGKPGARPPPEGASWDAGPGRAPSAWTVQAEGGPSPGPAEVRPTEGPLPASLEPRIVMGEETCQAAPLPRATMPELRDWEGGHANLNPPPEFCSQGDPPVPFPAPDSDSYFTPPSTPTKTASTLLPGPGPHRDAQDAQAELGDSPPASPTGSYITADGDSWASSPSCSLSLQALAEGLDVPSGWGFSPSGSVVDERELPPAGTPDSSSPESSLSADSSSSWGQEGHFFELDFLANDPMIPAYLLPFQGSLIFQVEAVEVTPLPHEEEEVEEEEQEEEQEVPLPRGDLAGEGEDDSTFASSLQSLSDLSITEGVDEAFAFRDDTSAASSDPDSASYTGADDERLYSGEPHAQPATLLQDSPGEAASWGPELALGVSKGEAGQAAKNQEPISEIMRVGPAAAQVSSAMAPHIPQESLDLTGVSPQAQGEEPGSTMGPVPVAPIMSQPLQEGDTATLGPEPWILKREADLNSLQTLKEDTGQGFAAATSPEPQPEVDPAAFPPFQDAGIPWVQESASETSPEPQLEEEELTASSHLLPLVQGSASEASPEPQSEEDLTASLPLKDEGLPLVQGSASEASPELQSEEEDLTASSTPQDAGLPLVQGSASEASPELQSEEKDLTASSTPQDAGLPLVQGSASEASPESQSEEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQESASEVSPEPQSEEDLTASLPLKDESLPLVQGSASKASPEPQSEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQESASEVSPEPQSEEDLTASLPLKDESLPLVQGSASEASPEPQSEDLTASLPLKDEGLPLVQGSASEASPEPQSEEDLTASPPLQDTDLPLVQGSVSEASPEPQSEEDLTASPPLQDAGLPLVQGSASDASPESQSEDLRASLHLQDAGLRLVQGSVSEVSPEPQSEEEDLTASPPLQDAGLPLVQGSASEASPDHQSDLKASPPLQDAGLPLVHGPASEASPEPQSEEEELTASLPLQDTGLHLVQGSASKASPEPQSEEEELTASPPLQDTGLPLVHGSASEASPELQSEEVTASPPLQDTGLPLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVQGSVSEASTEPQSEEEELTASLHLQDTGFSLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVHGSASEASPELQSEEVTASPPLQDTGLPLVQGSASDASSEPQSEEELTASPPLQDAGLPLVQGSASKVSPEPQSEEEDLTASPPVKDAGLPLVQGSASDASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPLVQGSASDASSEPQSEEEELTASPPLQDAGLPLVQGSASEASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPFVQGSASEASSEPQSEEELTASPPLQDAGLPLVQGSASEASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPFVQGSASEASSEPQSEEELTASPTLQDAGLPLVQGSASKASPELQSEVTASPPLQVAGLPLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVQGSASEASPESQSEEDLTASSPLKDAGLPLVQGSAFEASLEPHSEEEDLTASPPLQDTGLPLVQGSAFKASPEPHSEEEDLTASLPLQDAGLPFVQGSASEASSEPQSEEELTALPTLQDAGLPLVQGSASKASPEPQSEDLTASPPLQDAGLPFVQGSASETSPEPHSEEELTASPPLQDTGLPLVQGSASEASLEPHSEEELTASSPLQDAGLPLVQGSASEASPEPHSEEEELIAFPPQQDAGLPSSQVSATSASPQALMTDTGCTQKTEPTTTAAHRKGRKTLGLRPAPEERDPDHTGGSDSLALDQIHLGGPDLPADARTPLEGDAGPSKPATEIPDTPKPFTAAQGPPKPDSSGEEVAEGILAPEQEACHDICAHGGDGAESSSPPKVALGVEHQGHEALKPVVHGPGVCPTASLEVGQLGPPSPVEEGRATLGHRLPMAVGSEAGLGSCSQSPSRAVPRLGGHCAKDPAPTSPLPLRQPKPVLGPGKGERAQAALGVLGPSPLQPPESPIGGLPSAPQDRIQGPEPPAPGILMEAVPTPLASPAPCPCRGPREDLVEGAEPLGSPSHPPPRPRAQRAVAASSGITNPPGAGQVSLPPHPTLLSPKAAPKRGTHAKDPASRLSPPRQVPPGSGPRSPAGPRGLPATEQQDDGDSLEEDSPRALGSGQHSDSHGESSAELEEQDLPGPQTAQCPAQAPAGSGSEETVAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHRAAAEKFKVPSEPSALVPESAPGPRVRPECEEEEEEEDEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNQSDIVNAIMELTM", "length": 2616, "header": "tr|A0A3Q1MNH6-1|A0ABI0NMW2_BOVIN Computationally mapped isoform of NAC alpha domain containing OS=Bos taurus OX=9913 GN=NACAD PE=4 SV=3 CANONICAL=A0ABI0NMW2-1" }, "locus": { "chromosome": "4", "start_pos": 76548689, "end_pos": 76537740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086415.3", "url": "https://www.ensembl.org/id/ENSBTAT00000086415.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071083.3", "url": "https://www.ensembl.org/id/ENSBTAP00000071083.3" } ] } }, { "isoform_ac": "A0AAA9SJ87-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW2/entry#A0AAA9SJ87-1", "sequence": { "sequence": "MPGEAARAELLLPEAGGPGPRTDLSCDAAEATTPKGDRLEHCALTSGPSTLALTFLHGKPGARPPPEGASWDAGPGRAPSAWTVQAEGGPSPGPAEVRPTEGPLPASLEPRIVMGEETCQAAPLPRATMPELRDWEGGHANLNPPPEFCSQGDPPVPFPAPDSDSYFTPPSTPTKTASTLLPGPGPHRDAQDAQAELGDSPPASPTGSYITADGDSWASSPSCSLSLQALAEGLDVPSGWGFSPSGSVVDERELPPAGTPDSSSPESSLSADSSSSWGQEGHFFELDFLANDPMIPAYLLPFQGSLIFQVEAVEVTPLPHEEEEVEEEEQEEEQEVPLPRGDLAGEGEDDSTFASSLQSLSDLSITEGVDEAFAFRDDTSAASSDPDSASYTGADDERLYSGEPHAQPATLLQDSPGEAASWGPELALGVSKGEAGQAAKNQEPISEIMRVGPAAAQVSSAMAPHIPQESLDLTGVSPQAQGEEPGSTMGPVPVAPIMSQPLQEGDTATLGPEPWILKREADLNSLQTLKEDTGQGFAAATSPEPQPEVDPAAFPPFQDAGIPWVQESASETSPEPQLEEEELTASSHLLPLVQGSASEASPEPQSEEDLTASLPLKDEGLPLVQGSASEASPESQSEEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQESASEVSPEPQSEEDLTASLPLKDESLPLVQGSASEASPEPQSEDLTASLPLKDEGLPLVQGSASEASPEPQSEEDLTASPPLQDTDLPLVQGSVSEASPEPQSEEDLTASPPLQDAGLPLVQGSASDASPESQSEDLRASLHLQDAGLRLVQGSVSEVSPEPQSEEEDLTASPPLQDAGLPLVQGSASEASPDHQSDLKASPPLQDAGLPLVHGPASEASPEPQSEEEELTASLPLQDTGLHLVQGSASKASPEPQSEEEELTASPPLQDTGLPLVHGSASEASPELQSEEVTASPPLQDTGLPLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVQGSVSEASTEPQSEEEELTASLHLQDTGFSLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVHGSASEASPELQSEEVTASPPLQDTGLPLVQGSASDASSEPQSEEELTASPPLQDAGLPLVQGSASKVSPEPQSEEEDLTASPPVKDAGLPLVQGSASDASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPLVQGSASDASSEPQSEEEELTASPPLQDAGLPLVQGSASEASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPFVQGSASEASSEPQSEEELTASPPLQDAGLPLVQGSASEASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPFVQGSASEASSEPQSEEELTASPTLQDAGLPLVQGSASKASPELQSEVTASPPLQVAGLPLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVQGSASEASPESQSEEDLTASSPLKDAGLPLVQGSAFEASLEPHSEEEDLTASPPLQDTGLPLVQGSAFKASPEPHSEEEDLTASLPLQDAGLPFVQGSASEASSEPQSEEELTALPTLQDAGLPLVQGSASKASPEPQSEDLTASPPLQDAGLPFVQGSASETSPEPHSEEELTASPPLQDTGLPLVQGSASEASLEPHSEEELTASSPLQDAGLPLVQGSASEASPEPHSEEEELIAFPPQQDAGLPSSQVSATSASPQALMTDTGCTQKTEPTTTAAHRKGRKTLGLRPAPEERDPDHTGGSDSLALDQIHLGGPDLPADARTPLEGDAGPSKPATEIPDTPKPFTAAQGPPKPDSSGEEVAEGILAPEQEACHDICAHGGDGAESSSPPKVALGVEHQGHEALKPVVHGPGVCPTASLEVGQLGPPSPVEEGRATLGHRLPMAVGSEAGLGSCSQSPSRAVPRLGGHCAKDPAPTSPLPLRQPKPVLGPGKGERAQAALGVLGPSPLQPPESPIGGLPSAPQDRIQGPEPPAPGILMEAVPTPLASPAPCPCRGPREDLVEGAEPLGSPSHPPPRPRAQRAVAASSGITNPPGAGQVSLPPHPTLLSPKAAPKRGTHAKDPASRLSPPRQVPPGSGPRSPAGPRGLPATEQQDDGDSLEEDSPRALGSGQHSDSHGESSAELEEQDLPGPQTAQCPAQAPAGSGSEETVAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHRAAAEKFKVPSEPSALVPESAPGPRVRPECEEEEEEEDEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNQSDIVNAIMELTM", "length": 2491, "header": "tr|A0AAA9SJ87-1|A0ABI0NMW2_BOVIN Computationally mapped isoform of NAC alpha domain containing OS=Bos taurus OX=9913 GN=NACAD PE=4 SV=2 CANONICAL=A0ABI0NMW2-1" }, "locus": { "chromosome": "4", "start_pos": 76548689, "end_pos": 76537740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088550.2", "url": "https://www.ensembl.org/id/ENSBTAT00000088550.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083872.2", "url": "https://www.ensembl.org/id/ENSBTAP00000083872.2" } ] } }, { "isoform_ac": "A0ABI0NMW2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW2/entry#A0ABI0NMW2-1", "sequence": { "sequence": "MPGEAARAELLLPEAGGPGPRTDLSCDAAEATTPKGDRLEHCALTSGPSTLALTFLHGKPGARPPPEGASWDAGPGRAPSAWTVQAEGGPSPGPAEVRPTEGPLPASLEPRIVMGEETCQAAPLPRATMPELRDWEGGHANLNPPPEFCSQGDPPVPFPAPDSDSYFTPPSTPTKTASTLLPGPGPHRDAQDAQAELGDSPPASPTGSYITADGDSWASSPSCSLSLQALAEGLDVPSGWGFSPSGSVVDERELPPAGTPDSSSPESSLSADSSSSWGQEGHFFELDFLANDPMIPAYLLPFQGSLIFQVEAVEVTPLPHEEEEVEEEEQEEEQEVPLPRGDLAGEGEDDSTFASSLQSLSDLSITEGVDEAFAFRDDTSAASSDPDSASYTGADDERLYSGEPHAQPATLLQDSPGEAASWGPELALGVSKGEAGQAAKNQEPISEIMRVGPAAAQVSSAMAPHIPQESLDLTGVSPQAQGEEPGSTMGPVPVAPIMSQPLQEGDTATLGPEPWILKREADLNSLQTLKEDTGQGFAAATSPEPQPEVDPAAFPPFQDAGIPWVQESASETSPEPQLEEEELTASSHLLPLVQGSASEASPEPQSEEDLTASLPLKDEGLPLVQGSASEASPELQSEEEDLTASSTPQDAGLPLVQGSASEASPELQSEEKDLTASSTPQDAGLPLVQGSASEASPESQSEEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQESASEVSPEPQSEEDLTASLPLKDESLPLVQGSASKASPEPQSEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQESASEVSPEPQSEEDLTASLPLKDESLPLVQGSASEASPEPQSEDLTASLPLKDEGLPLVQGSASEASPEPQSEEDLTASPPLQDTDLPLVQGSVSEASPEPQSEEDLTASPPLQDAGLPLVQGSASDASPESQSEDLRASLHLQDAGLRLVQGSVSEVSPEPQSEEEDLTASPPLQDAGLPLVQGSASEASPDHQSDLKASPPLQDAGLPLVHGPASEASPEPQSEEEELTASLPLQDTGLHLVQGSAFKASPELQSEEEVTASSPLQDTGLHLVQGSASKASPEPQSEEEELTASPPLQDTGLPLVHGSASEASPELQSEEVTASPPLQDTGLPLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVQGSVSEASTEPQSEEEELTASLHLQDTGFSLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVHGSASEASPELQSEEVTASPPLQDTGLPLVQGSASDASSEPQSEEELTASPPLQDAGLPLVQGSASKVSPEPQSEEEDLTASPPVKDAGLPLVQGSASDASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPLVQGSASDASSEPQSEEEELTASPPLQDAGLPLVQGSASEASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPFVQGSASEASSEPQSEEELTASPPLQDAGLPLVQGSASEASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPFVQGSASEASSEPQSEEELTASPTLQDAGLPLVQGSASKASPELQSEVTASPPLQVAGLPLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVQGSASEASPESQSEEDLTASSPLKDAGLPLVQGSAFEASLEPHSEEEDLTASPPLQDTGLPLVQGSAFKASPEPHSEEEDLTASLPLQDAGLPFVQGSASEASSEPQSEEELTALPTLQDAGLPLVQGSASKASPEPQSEDLTASPPLQDAGLPFVQGSASETSPEPHSEEELTASPPLQDTGLPLVQGSASEASLEPHSEEELTASSPLQDAGLPLVQGSASEASPEPHSEEEELIAFPPQQDAGLPSSQVSATSASPQALMTDTGCTQKTEPTTTAAHRKGRKTLGLRPAPEERDPDHTGGSDSLALDQIHLGGPDLPADARTPLEGDAGPSKPATEIPDTPKPFTAAQGPPKPDSSGEEVAEGILAPEQEACHDICAHGGDGAESSSPPKVALGVEHQGHEALKPVVHGPGVCPTASLEVGQLGPPSPVEEGRATLGHRLPMAVGSEAGLGSCSQSPSRAVPRLGGHCAKDPAPTSPLPLRQPKPVLGPGKGERAQAALGVLGPSPLQPPESPIGGLPSAPQDRIQGPEPPAPGILMEAVPTPLASPAPCPCRGPREDLVEGAEPLGSPSHPPPRPRAQRAVAASSGITNPPGAGQVSLPPHPTLLSPKAAPKRGTHAKDPASRLSPPRQVPPGSGPRSPAGPRGLPATEQQDDGDSLEEDSPRALGSGQHSDSHGESSAELEEQDLPGPQTAQCPAQAPAGSGSEETVAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHRAAAEKFKVPSEPSALVPESAPGPRVRPECEEEEEEEDEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNQSDIVNAIMELTM", "length": 2647, "header": "tr|A0ABI0NMW2-1|A0ABI0NMW2_BOVIN Isoform 1 of NAC alpha domain containing OS=Bos taurus OX=9913 GN=NACAD PE=4 SV=1 CANONICAL=A0ABI0NMW2-1" }, "locus": { "chromosome": "4", "start_pos": 76548689, "end_pos": 76537740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145270.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145270.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104045.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104045.1" } ] } }, { "isoform_ac": "A0ABI0NXZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW2/entry#A0ABI0NXZ0-1", "sequence": { "sequence": "MPGEAARAELLLPEAGGPGPRTDLSCDAAEATTPKGDRLEHCALTSGPSTLALTFLHGKPGARPPPEGASWDAGPGRAPSAWTVQAEGGPSPGPAEVRPTEGPLPASLEPRIVMGEETCQAAPLPRATMPELRDWEGGHANLNPPPEFCSQGDPPVPFPAPDSDSYFTPPSTPTKTASTLLPGPGPHRDAQDAQAELGDSPPASPTGSYITADGDSWASSPSCSLSLQALAEGLDVPSGWGFSPSGSVVDERELPPAGTPDSSSPESSLSADSSSSWGQEGHFFELDFLANDPMIPAYLLPFQGSLIFQVEAVEVTPLPHEEEEVEEEEQEEEQEVPLPRGDLAGEGEDDSTFASSLQSLSDLSITEGVDEAFAFRDDTSAASSDPDSASYTGADDERLYSGEPHAQPATLLQDSPGEAASWGPELALGVSKGEAGQAAKNQEPISEIMRVGPAAAQVSSAMAPHIPQESLDLTGVSPQAQGEEPGSTMGPVPVAPIMSQPLQEGDTATLGPEPWILKREADLNSLQTLKEDTGQGFAAATSPEPQPEVDPAAFPPFQDAGIPWVQESASETSPEPQLEEEELTASSHLLPLVQGSASEASPEPQSEEDLTASLPLKDEGLPLVQGSASEASPELQSEEEDLTASSTPQDAGLPLVQGSASEASPELQSEEKDLTASSTPQDAGLPLVQGSASEASPESQSEEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQESASEVSPEPQSEEDLTASLPLKDESLPLVQGSASKASPEPQSEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQGSASEASPESQSEEDLTASSTPQDAGLPLVQESASEVSPEPQSEEDLTASLPLKDESLPLVQGSASEASPEPQSEDLTASLPLKDEGLPLVQGSASEASPEPQSEEDLTASPPLQDTDLPLVQGSVSEASPEPQSEEDLTASPPLQDAGLPLVQGSASDASPESQSEDLRASLHLQDAGLRLVQGSVSEVSPEPQSEEEDLTASPPLQDAGLPLVQGSASEASPDHQSDLKASPPLQDAGLPLVHGPASEASPEPQSEEEELTASLPLQDTGLHLVQGSAFKASPELQSEEEVTASSPLQDTGLHLVQGSASKASPEPQSEEEELTASPPLQDTGLPLVHGSASEASPELQSEEVTASPPLQDTGLPLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVQGSVSEASTEPQSEEEELTASLHLQDTGFSLVQGSASDASSEPQSEEEELTASSHLQDAGLPLVHGSASEASPELQSEEVTASPPLQDTGLPLVQGSASDASSEPQSEEELTASPPLQDAGLPLVQGSASKVSPEPQSEEEDLTASPPVKDAGLPLVQGSASDASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPFVQGSASEASSEPQSEEELTASPPLQDAGLPLVQGSASEASSEPQSEEEELTASPTLQDAGLPLVQGSASEASSEPHSEEELTASPPLQDAGLPFVQGSASEASSEPQSEEELTASPTLQDAGLPLVQGSASEASPESQSEEDLTASSPLKDAGLPLVQGSAFEASLEPHSEEEDLTASPPLQDTGLPLVQGSAFKASPEPHSEEEDLTASLPLQDAGLPFVQGSASEASSEPQSEEELTALPTLQDAGLPLVQGSASKASPEPQSEDLTASPPLQDAGLPFVQGSASETSPEPHSEEELTASPPLQDTGLPLVQGSASEASLEPHSEEELTASSPLQDAGLPLVQGSASEASPEPHSEEEELIAFPPQQDAGLPSSQVSATSASPQALMTDTGCTQKTEPTTTAAHRKGRKTLGLRPAPEERDPDHTGGSDSLALDQIHLGGPDLPADARTPLEGDAGPSKPATEIPDTPKPFTAAQGPPKPDSSGEEVAEGILAPEQEACHDICAHGGDGAESSSPPKVALGVEHQGHEALKPVVHGPGVCPTASLEVGQLGPPSPVEEGRATLGHRLPMAVGSEAGLGSCSQSPSRAVPRLGGHCAKDPAPTSPLPLRQPKPVLGPGKGERAQAALGVLGPSPLQPPESPIGGLPSAPQDRIQGPEPPAPGILMEAVPTPLASPAPCPCRGPREDLVEGAEPLGSPSHPPPRPRAQRAVAASSGITNPPGAGQVSLPPHPTLLSPKAAPKRGTHAKDPASRLSPPRQVPPGSGPRSPAGPRGLPATEQQDDGDSLEEDSPRALGSGQHSDSHGESSAELEEQDLPGPQTAQCPAQAPAGSGSEETVAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHRAAAEKFKVPSEPSALVPESAPGPRVRPECEEEEEEEDEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNQSDIVNAIMELTM", "length": 2491, "header": "tr|A0ABI0NXZ0-1|A0ABI0NXZ0_BOVIN Computationally mapped isoform of NAC alpha domain containing OS=Bos taurus OX=9913 GN=NACAD PE=4 SV=1 CANONICAL=A0ABI0NMW2-1" }, "locus": { "chromosome": "4", "start_pos": 76548689, "end_pos": 76537740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147807.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147807.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105791.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105791.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2195, "start_aa": "Thr", "end_pos": 2195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2195", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2255, "start_aa": "Thr", "end_pos": 2255, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2255", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 259, "start_aa": "Thr", "end_pos": 259, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr259", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nascent polypeptide-associated complex", "id": "GO:0005854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005854", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 2621, "end_pos": 2623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2634, "end_pos": 2636, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NMW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW2" }, { "id": "PS51151", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51151" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NAC-A/B", "eco_id": "ECO_0000259", "start_pos": 2495, "end_pos": 2560, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 259, 2195, 2255 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 2621, "end_pos": 2623 }, { "start_pos": 2634, "end_pos": 2636 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NTP5-1", "uniprot_ac": "A0ABI0NTP5", "uniprot_id": "A0ABI0NTP5_BOVIN", "mass": { "chemical_mass": 75581.0, "monoisotopic_mass": 75581.0 }, "refseq": {}, "gene_names": [ { "name": "DYNC1I1", "type": "recommended", "evidence": [ { "id": "A0ABI0NTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5" } ] } ], "protein_names": [ { "name": "Dynein cytoplasmic 1 intermediate chain 1", "type": "synonym", "evidence": [ { "id": "A0ABI0NTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ22", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ22#function" }, { "database": "UniProtKB", "id": "ARBA00054949", "url": "https://www.uniprot.org/uniprotkb/ARBA00054949#function" }, { "database": "UniProtKB", "id": "A0ABI0P0Q8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Q8#function" }, { "database": "UniProtKB", "id": "A0ABI0P7J3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7J3#function" }, { "database": "UniProtKB", "id": "A0AAF6Z1Q0", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z1Q0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTP5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DYNC1I1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5", "locus": { "chromosome": "4", "start_pos": 13440805, "end_pos": 13141121, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000027134", "url": "https://www.ensembl.org/id/ENSBTAG00000027134" } ] } } ], "crossref": [ { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12442", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12442", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12442:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12442:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11540", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11540", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAF6Z1Q0", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z1Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z1Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z1Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ22", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ22-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTP5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTP5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0Q8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P7J3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P7J3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7J3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVPDDSDLDRKRRETEALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKITQVDFLPREVVSYSKETQTPLATHQSEEDEDDEEMVEPKGDQDSEQENEDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKPTRFLCPWDSPGKNTAVGCHAFLQGIFLTQESIPHVLCLLCWQHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQGGKEVAVGDSEGRIWIYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGAVELSA", "length": 671, "header": "tr|A0ABI0NTP5-1|A0ABI0NTP5_BOVIN Isoform 1 of Dynein cytoplasmic 1 intermediate chain 1 OS=Bos taurus OX=9913 GN=DYNC1I1 PE=3 SV=1 CANONICAL=A0ABI0NTP5-1" }, "isoforms": [ { "isoform_ac": "A0AAF6Z1Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5/entry#A0AAF6Z1Q0-1", "sequence": { "sequence": "MSNSVRPRRRQPPRLSRPWDSPGKNTGVGCHFLLQCMKVKSLSRVRFLATPWTAAYQAPPSMGFSRRRLHKLGVSKITQVDFLPREVVSYSKETQTPLATHQSEEDEDDEEMVEPKGDQDSEQENEDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQGGKEVAVGDSEGRIWIYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGAVELSA", "length": 569, "header": "tr|A0AAF6Z1Q0-1|A0ABI0NTP5_BOVIN Computationally mapped isoform of Dynein cytoplasmic 1 intermediate chain 1 OS=Bos taurus OX=9913 GN=DYNC1I1 PE=3 SV=1 CANONICAL=A0ABI0NTP5-1" }, "locus": { "chromosome": "4", "start_pos": 13440248, "end_pos": 13141134, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020774.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020774.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020774.5", "url": "https://www.ensembl.org/id/ENSBTAP00000020774.5" } ] } }, { "isoform_ac": "A0ABI0NQ22-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5/entry#A0ABI0NQ22-1", "sequence": { "sequence": "MLQVYYAVISQCLKETNMSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVPDDSDLDRKRRETEALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKITQVDFLPREVVSYSKETQTPLATHQSEEDEDDEEMVEPKGDQDSEQENEDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQGGKEVAVGDSEGRIWIYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGAVELSA", "length": 645, "header": "tr|A0ABI0NQ22-1|A0ABI0NQ22_BOVIN Computationally mapped isoform of Cytoplasmic dynein 1 intermediate chain 1 OS=Bos taurus OX=9913 GN=DYNC1I1 PE=3 SV=1 CANONICAL=A0ABI0NTP5-1" }, "locus": { "chromosome": "4", "start_pos": 13440248, "end_pos": 13061474, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146301.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146301.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105353.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105353.1" } ] } }, { "isoform_ac": "A0ABI0NTP5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5/entry#A0ABI0NTP5-1", "sequence": { "sequence": "MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVPDDSDLDRKRRETEALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKITQVDFLPREVVSYSKETQTPLATHQSEEDEDDEEMVEPKGDQDSEQENEDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKPTRFLCPWDSPGKNTAVGCHAFLQGIFLTQESIPHVLCLLCWQHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQGGKEVAVGDSEGRIWIYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGAVELSA", "length": 671, "header": "tr|A0ABI0NTP5-1|A0ABI0NTP5_BOVIN Isoform 1 of Dynein cytoplasmic 1 intermediate chain 1 OS=Bos taurus OX=9913 GN=DYNC1I1 PE=3 SV=1 CANONICAL=A0ABI0NTP5-1" }, "locus": { "chromosome": "4", "start_pos": 13440248, "end_pos": 13106276, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141521.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141521.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104216.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104216.1" } ] } }, { "isoform_ac": "A0ABI0P0Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5/entry#A0ABI0P0Q8-1", "sequence": { "sequence": "MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVPDDSDLDRKRRETEALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKITQVDFLPREVVSYSKETQTPLATHQSEEDEDDEEMVEPKGDQDSEQENEDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQGGKEVAVGDSEGRIWIYDVGEDPLIKDQATF", "length": 582, "header": "tr|A0ABI0P0Q8-1|A0ABI0P0Q8_BOVIN Computationally mapped isoform of Cytoplasmic dynein 1 intermediate chain 1 OS=Bos taurus OX=9913 GN=DYNC1I1 PE=3 SV=1 CANONICAL=A0ABI0NTP5-1" }, "locus": { "chromosome": "4", "start_pos": 13421715, "end_pos": 13106276, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145091.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145091.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107399.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107399.1" } ] } }, { "isoform_ac": "A0ABI0P7J3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5/entry#A0ABI0P7J3-1", "sequence": { "sequence": "MIVFQMWGKCLVLSSNCVLKRKETRADMQQKKEPVPDDSDLDRKRRETEALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKITQVDFLPREVVSYSKETQTPLATHQSEEDEDDEEMVEPKGDQDSEQENEDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQGGKEVAVGDSEGRIWIYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGAVELSA", "length": 597, "header": "tr|A0ABI0P7J3-1|A0ABI0P7J3_BOVIN Computationally mapped isoform of Cytoplasmic dynein 1 intermediate chain 1 OS=Bos taurus OX=9913 GN=DYNC1I1 PE=3 SV=1 CANONICAL=A0ABI0NTP5-1" }, "locus": { "chromosome": "4", "start_pos": 13440248, "end_pos": 13114669, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154376.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154376.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107538.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107538.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 77, "start_aa": "Thr", "end_pos": 77, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr77", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTP5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTP5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTP5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5" } ], "pmid": "" }, { "name": "cytoplasmic dynein complex", "id": "GO:0005868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005868", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTP5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule-based 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"https://www.uniprot.org/uniprotkb/A0ABI0NQM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3L7", "url": "https://www.uniprot.org/uniprotkb/F1N3L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3L7-1", "url": "https://www.uniprot.org/uniprotkb/F1N3L7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVDPVDLEDYLLTHPLAVDSGPLRDLVEFPPDDIEVVYSPRDCRTLVSAVPEESEMDPHVRDCIRSYTEDWAIVIRKYHKLGTGFNPNTLDKQKERQKGLPKQVFESDEAPDGNNYQDEQDDLKRRSMSIDDTPRGSWACSIFDLKNSLPDALLPNLLDRTPNEEIDRQNDDQRKSNRHKELFALHPSPDEEEPIERLSVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFASLALYDVKEKKKISENFYFDLNSEQMKGLLRPHVPPAAITTLARSAIFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSSAGSLERDSTEVEISTGERKGSWSERRNSSIVGRRSLERTTSGDDACNLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPLYCLTPELLQVKPYPDSRVRPTREILEFPARDVYVPNTTYRNLLYIYPQSLNFANRQGSARNITVKVQFMYGEDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPPQAYSVLSPEVPLPGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHMFPVRIGDMRIMENNLENELKSSISALNSSQLEPVVRFLHLLLDKLILLVVRPPVIAGQIVNLGQASFEAMASIINRLHKNLEGNHDQHGRNCLLASYIYYVFRLPNTYPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIISSKGLDRSNSWVNTGGPKAAPWGSNPSPSAESTQAMDRSCNRMSSHTETSSFLQTLTGRLPTKKLFHEELALQWVVCSGSVRESALQQAWFFFELMVKSMVHHLYFNDKLDAPRKTRFPERFMDDIAALVSTIASDIVSRFQKDTEMVERLNTSLAFFLNDLLSVMDRGFVFSLIKTCYKQVSSKLYSLPSPSVLVSLRLDFLRIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTNVQDQKIANMFELSVPFRQQHYLAGLVLTELAVILDPDAEGLFGLHKKVINMVHNLLSSHDSDPRYSDPQTKARVAMLYLPLIGIVMETVPQLYDFTETHNQRGRPICIATDDYESESGSMISQTVAMAIAGTSVPQLTRPGSFLLTSTSGRQHTTFSAESSRSLLICLLWVLKNADETVLQKWFTDLSVLQLNRLLDLLYLCVSCFEYKGKKVFERMNSLTFKKSKDMRAKLEEAILGSIGARQEMVRRSRGQLGTYTMSSPSERSPSGSAFGSQENLRWRKDMTHWRQNTEKLDKSRAEIEHEALIDGNLATEANLIILDTLEIVVQTVSVTESKESILGGVLKVLLHSMACNQSAVYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRHCSSSISTIRSHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTESGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLSTIHGKLQEAFSKIVHQSTGWERMFGTYFRVGFYGTKFGDLDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVVEVIKDSNPVDKCKLDPNKAYIQITYVEPYFDTYEMKDRITYFDKNYNLRRFMYCTPFTLDGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKAVLPVTCHRDSFSRMSLRKMDL", "length": 2140, "header": "tr|A0ABI0NQM2-1|A0ABI0NQM2_BOVIN Isoform 1 of Dedicator of cytokinesis 7 OS=Bos taurus OX=9913 GN=DOCK7 PE=3 SV=1 CANONICAL=A0ABI0NQM2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SHL0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQM2/entry#A0AAA9SHL0-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVDPVDLEDYLLTHPLAVDSGPLRDLVEFPPDDIEVVYSPRDCRTLVSAVPEESEMDPHVRDCIRSYTEDWAIVIRKYHKLGTGFNPNTLDKQKERQKGLPKQVFESDEAPDGNNYQDEQDDLKRRSMSIDDTPRGSWACSIFDLKNSLPDALLPNLLDRTPNEEIDRQNDDQRKSNRHKELFALHPSPDEEEPIERLSVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFASLALYDVKEKKKISENFYFDLNSEQMKGLLRPHVPPAAITTLARSAIFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSSAGSLERDSTEVEISTGERKGSWSERRNSSIVGRRSLERTTSGDDACNLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPLYCLTPELLQVKPYPDSRVRPTREILEFPARDVYVPNTTYRNLLYIYPQSLNFANRQGSARNITVKVQFMYGEDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPPQAYSVLSPEVPLPGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHMFPVRIGDMRIMENNLENELKSSISALNSSQLEPVVRFLHLLLDKLILLVVRPPVIAGQIVNLGQASFEAMASIINRLHKNLEGNHDQHGRNCLLASYIYYVFRLPNTYPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIISSKAMDRSCNRMSSHTETSSFLQTLTGRLPTKKLFHEELALQWVVCSGSVRESALQQAWFFFELMVKSMVHHLYFNDKLDAPRKTRFPERFMDDIAALVSTIASDIVSRFQKDTEMVERLNTSLAFFLNDLLSVMDRGFVFSLIKTCYKQVSSKLYSLPSPSVLVSLRLDFLRIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTNVQDQKIANMFELSVPFRQQHYLAGLVLTELAVILDPDAEGLFGLHKKVINMVHNLLSSHDSDPRYSDPQTKARVAMLYLPLIGIVMETVPQLYDFTETHNQRGRPICIATDDYESESGSMISQTVAMAIAGTSVPQLTRPGSFLLTSTSGRQHTTFSAESSRSLLICLLWVLKNADETVLQKWFTDLSVLQLNRLLDLLYLCVSCFEYKGKKVFERMNSLTFKKSKDMRAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQNTEKLDKSRAEIEHEALIDGNLATEANLIILDTLEIVVQTVSVTESKESILGGVLKVLLHSMACNQSAVYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRHCSSSISTIRSHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTESGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLSTIHGKLQEAFSKIVHQDGKRMFGTYFRVGFYGTKFGDLDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVVEVIKDSNPVDKCKLDPNKAYIQITYVEPYFDTYEMKDRITYFDKNYNLRRFMYCTPFTLDGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKAVLPVTCHRYACFFLLFCIFRKMKST", "length": 2102, "header": "tr|A0AAA9SHL0-1|A0ABI0NQM2_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 7 OS=Bos taurus OX=9913 GN=DOCK7 PE=3 SV=1 CANONICAL=A0ABI0NQM2-1" }, "locus": { "chromosome": "3", "start_pos": 83111673, "end_pos": 82924988, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126665.2", "url": "https://www.ensembl.org/id/ENSBTAT00000126665.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085689.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085689.1" } ] } }, { "isoform_ac": "A0ABI0NQM2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQM2/entry#A0ABI0NQM2-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVDPVDLEDYLLTHPLAVDSGPLRDLVEFPPDDIEVVYSPRDCRTLVSAVPEESEMDPHVRDCIRSYTEDWAIVIRKYHKLGTGFNPNTLDKQKERQKGLPKQVFESDEAPDGNNYQDEQDDLKRRSMSIDDTPRGSWACSIFDLKNSLPDALLPNLLDRTPNEEIDRQNDDQRKSNRHKELFALHPSPDEEEPIERLSVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFASLALYDVKEKKKISENFYFDLNSEQMKGLLRPHVPPAAITTLARSAIFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSSAGSLERDSTEVEISTGERKGSWSERRNSSIVGRRSLERTTSGDDACNLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPLYCLTPELLQVKPYPDSRVRPTREILEFPARDVYVPNTTYRNLLYIYPQSLNFANRQGSARNITVKVQFMYGEDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPPQAYSVLSPEVPLPGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHMFPVRIGDMRIMENNLENELKSSISALNSSQLEPVVRFLHLLLDKLILLVVRPPVIAGQIVNLGQASFEAMASIINRLHKNLEGNHDQHGRNCLLASYIYYVFRLPNTYPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIISSKGLDRSNSWVNTGGPKAAPWGSNPSPSAESTQAMDRSCNRMSSHTETSSFLQTLTGRLPTKKLFHEELALQWVVCSGSVRESALQQAWFFFELMVKSMVHHLYFNDKLDAPRKTRFPERFMDDIAALVSTIASDIVSRFQKDTEMVERLNTSLAFFLNDLLSVMDRGFVFSLIKTCYKQVSSKLYSLPSPSVLVSLRLDFLRIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTNVQDQKIANMFELSVPFRQQHYLAGLVLTELAVILDPDAEGLFGLHKKVINMVHNLLSSHDSDPRYSDPQTKARVAMLYLPLIGIVMETVPQLYDFTETHNQRGRPICIATDDYESESGSMISQTVAMAIAGTSVPQLTRPGSFLLTSTSGRQHTTFSAESSRSLLICLLWVLKNADETVLQKWFTDLSVLQLNRLLDLLYLCVSCFEYKGKKVFERMNSLTFKKSKDMRAKLEEAILGSIGARQEMVRRSRGQLGTYTMSSPSERSPSGSAFGSQENLRWRKDMTHWRQNTEKLDKSRAEIEHEALIDGNLATEANLIILDTLEIVVQTVSVTESKESILGGVLKVLLHSMACNQSAVYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRHCSSSISTIRSHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTESGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLSTIHGKLQEAFSKIVHQSTGWERMFGTYFRVGFYGTKFGDLDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVVEVIKDSNPVDKCKLDPNKAYIQITYVEPYFDTYEMKDRITYFDKNYNLRRFMYCTPFTLDGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKAVLPVTCHRDSFSRMSLRKMDL", "length": 2140, "header": "tr|A0ABI0NQM2-1|A0ABI0NQM2_BOVIN Isoform 1 of Dedicator of cytokinesis 7 OS=Bos taurus OX=9913 GN=DOCK7 PE=3 SV=1 CANONICAL=A0ABI0NQM2-1" }, "locus": { "chromosome": "3", "start_pos": 83114905, "end_pos": 82924988, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145168.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145168.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105678.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105678.1" } ] } }, { "isoform_ac": "F1N3L7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQM2/entry#F1N3L7-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVDPVDLEDYLLTHPLAVDSGPLRDLVEFPPDDIEVVYSPRDCRTLVSAVPEESEMDPHVRDCIRSYTEDWAIVIRKYHKLGTGFNPNTLDKQKERQKGLPKQVFESDEAPDGNNYQDEQDDLKRRSMSIDDTPRGSWACSIFDLKNSLPDALLPNLLDRTPNEEIDRQNDDQRKSNRHKELFALHPSPDEEEPIERLSVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFASLALYDVKEKKKISENFYFDLNSEQMKGLLRPHVPPAAITTLARSAIFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSSAGSLERDSTEVEISTGERKGSWSERRNSSIVGRRSLERTTSGDDACNLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPLYCLTPELLQVKPYPDSRVRPTREILEFPARDVYVPNTTYRNLLYIYPQSLNFANRQGSARNITVKVQFMYGEDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPPQAYSVLSPEVPLPGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHMFPVRIGDMRIMENNLENELKSSISALNSSQLEPVVRFLHLLLDKLILLVVRPPVIAGQIVNLGQASFEAMASIINRLHKNLEGNHDQHGRNCLLASYIYYVFRLPNTYPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIISSKGLDRSNSWVNTGGPKAAPWGSNPSPSAESTQAMDRSCNRMSSHTETSSFLQTLTGRLPTKKLFHEELALQWVVCSGSVRESALQQAWFFFELMVKSMVHHLYFNDKLDAPRKTRFPERFMDDIAALVSTIASDIVSRFQKDTEMVERLNTSLAFFLNDLLSVMDRGFVFSLIKTCYKQVSSKLYSLPSPSVLVSLRLDFLRIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTNVQDQKIANMFELSVPFRQQHYLAGLVLTELAVILDPDAEGLFGLHKKVINMVHNLLSSHDSDPRYSDPQTKARVAMLYLPLIGIVMETVPQLYDFTETHNQRGRPICIATDDYESESGSMISQTVAMAIAGTSVPQLTRPGSFLLTSTSGRQHTTFSAESSRSLLICLLWVLKNADETVLQKWFTDLSVLQLNRLLDLLYLCVSCFEYKGKKVFERMNSLTFKKSKDMRAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQNTEKLDKSRAEIEHEALIDGNLATEANLIILDTLEIVVQTVSVTESKESILGGVLKVLLHSMACNQSAVYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRHCSSSISTIRSHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTESGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLSTIHGKLQEAFSKIVHQDGKRMFGTYFRVGFYGTKFGDLDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVVEVIKDSNPVDKCKLDPNKAYIQITYVEPYFDTYEMKDRITYFDKNYNLRRFMYCTPFTLDGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKAVLPVTCHRDSFSRMSLRKMDL", "length": 2129, "header": "tr|F1N3L7-1|A0ABI0NQM2_BOVIN Computationally mapped isoform of Dedicator of cytokinesis 7 OS=Bos taurus OX=9913 GN=DOCK7 PE=3 SV=5 CANONICAL=A0ABI0NQM2-1" }, "locus": { "chromosome": "3", "start_pos": 83114905, "end_pos": 82924988, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026487.8", "url": "https://www.ensembl.org/id/ENSBTAT00000026487.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026487.8", "url": "https://www.ensembl.org/id/ENSBTAP00000026487.8" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-8875555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8875555", "resource": "Reactome", "description": "MET activates RAP1 and RAC1" }, { "id": "R-BTA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-BTA-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQM2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQM2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQM2" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": 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] }, { "id": "A0A3Q1LLV5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSF2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSF2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALVASFNMTNPQPATERGLSEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTAGSQLLSNLDEDYQREGSTWLKPCCGKRAAVWQVFLLSASVNGFLVTCVILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLAILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMFRIWRVKRVIDGTTPATALLDLLGTTPGPEPAASWTLGLALPLPALPLPSSSWGCLCLAAYVLPVKVEMEMVIQQYEKAKAIQDEQLERLTQICQEQGFEIRQLRAHLAQQDLDLAAEREAALQAPHVLSQPRSRYKVVEAGTWAEETAAESVVEELQPAQEATVKDDMNSYISQYYNGPSSDSGVPEPAVCVVTTAAIDIHQPNVSSDLFSVDVPLKLGSEGTGASASSESATRSTRSSGTRAQSDSSQTLGSSTDCSAAREEPSPRPSPSALPLPPPPSQQHMAEATVQDLLSPLSEDPCPSRRALDSAPLAQPSPEGSAQPSPELEHRVSLFNQKNREGFTVFQIKPVIHFQPAAPVLEEKFRSLESKEQKLHRVPEA", "length": 587, "header": "tr|A0ABI0NSF2-1|A0ABI0NSF2_BOVIN Isoform 1 of Transmembrane protein 266 OS=Bos taurus OX=9913 GN=TMEM266 PE=4 SV=1 CANONICAL=A0ABI0NSF2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLV5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF2/entry#A0A3Q1LLV5-1", "sequence": { "sequence": "MWFCSHFKDEETGAQGDAVSSLGQPVNEAASLSEMFPVFVLLPSAREEGAEPGRSTWLKPCCGKRAAVWQVFLLSASVNGFLVTCVILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLAILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMFRIWRVKRVIDAYVLPVKVEMEMVIQQYEKAKAIQDEQLERLTQICQEQGFEIRQLRAHLAQQDLDLAAEREAALQAPHVLSQPRSRYKVVEAGTWAEETAAESVVEELQPAQEATVKDDMNSYISQYYNGPSSDSGVPEPAVCVVTTAAIDIHQPNVSSDLFSVDVPLKLGSEGTGASASSESATRSTRSSGTRAQSDSSQTLGSSTDCSAAREEPSPRPSPSALPLPPPPSQQHMAEATVQDLLSPLSEDPCPSRRALDSAPLAQPSPEGSAQPSPELEHRVSLFNQKNREGFTVFQIKPVIHFQPAAPVLEEKFRSLESKEQKLHRVPEA", "length": 517, "header": "tr|A0A3Q1LLV5-1|A0ABI0NSF2_BOVIN Computationally mapped isoform of Transmembrane protein 266 OS=Bos taurus OX=9913 GN=TMEM266 PE=4 SV=2 CANONICAL=A0ABI0NSF2-1" }, "locus": { "chromosome": "21", "start_pos": 31460425, "end_pos": 31413287, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078090.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078090.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057596.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057596.2" } ] } }, { "isoform_ac": "A0ABI0NSF2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF2/entry#A0ABI0NSF2-1", "sequence": { "sequence": "MALVASFNMTNPQPATERGLSEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTAGSQLLSNLDEDYQREGSTWLKPCCGKRAAVWQVFLLSASVNGFLVTCVILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLAILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMFRIWRVKRVIDGTTPATALLDLLGTTPGPEPAASWTLGLALPLPALPLPSSSWGCLCLAAYVLPVKVEMEMVIQQYEKAKAIQDEQLERLTQICQEQGFEIRQLRAHLAQQDLDLAAEREAALQAPHVLSQPRSRYKVVEAGTWAEETAAESVVEELQPAQEATVKDDMNSYISQYYNGPSSDSGVPEPAVCVVTTAAIDIHQPNVSSDLFSVDVPLKLGSEGTGASASSESATRSTRSSGTRAQSDSSQTLGSSTDCSAAREEPSPRPSPSALPLPPPPSQQHMAEATVQDLLSPLSEDPCPSRRALDSAPLAQPSPEGSAQPSPELEHRVSLFNQKNREGFTVFQIKPVIHFQPAAPVLEEKFRSLESKEQKLHRVPEA", "length": 587, "header": "tr|A0ABI0NSF2-1|A0ABI0NSF2_BOVIN Isoform 1 of Transmembrane protein 266 OS=Bos taurus OX=9913 GN=TMEM266 PE=4 SV=1 CANONICAL=A0ABI0NSF2-1" }, "locus": { "chromosome": "21", "start_pos": 31460425, "end_pos": 31392909, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154373.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154373.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105885.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105885.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSF2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF2" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSF2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF2" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSF2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "voltage-gated channel activity", "id": "GO:0022832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022832", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSF2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 411, "end_pos": 413 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NME6-1", "uniprot_ac": "A0ABI0NME6", "uniprot_id": "A0ABI0NME6_BOVIN", "mass": { "chemical_mass": 72093.0, "monoisotopic_mass": 72093.0 }, "refseq": {}, "gene_names": [ { "name": "SLC8B1", "type": "recommended", "evidence": [ { "id": "A0ABI0NME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6" } ] } ], "protein_names": [ { "name": "Mitochondrial sodium/calcium exchanger protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6/entry#names_and_taxonomy" } ] }, { "name": "Na(+)/K(+)/Ca(2+)-exchange protein 6", "type": "synonym", "evidence": [ { "id": "A0ABI0NME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6/entry#names_and_taxonomy" } ] }, { "name": "Sodium/calcium exchanger protein, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0ABI0NME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6/entry#names_and_taxonomy" } ] }, { "name": "Sodium/potassium/calcium exchanger 6", "type": "synonym", "evidence": [ { "id": "A0ABI0NME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 24 member 6", "type": "synonym", "evidence": [ { "id": "A0ABI0NME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 8 member B1", "type": "synonym", "evidence": [ { "id": "A0ABI0NME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NME6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC8B1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6", "locus": { "chromosome": "17", "start_pos": 61286705, "end_pos": 61316686, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011103", "url": "https://www.ensembl.org/id/ENSBTAG00000011103" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011103", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011103", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LSB1", "url": "https://www.orthodb.org/?gene=A0A3Q1LSB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MSI3", "url": "https://www.orthodb.org/?gene=F1MSI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12266", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12266", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12266:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12266:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-425561", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-425561", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8949215", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8949215", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "69955", "url": "https://www.rhea-db.org/rhea/69955", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72631", "url": "https://www.rhea-db.org/rhea/72631", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LSB1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TM44", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TM44-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NME6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NME6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MSI3", "url": "https://www.uniprot.org/uniprotkb/F1MSI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MSI3-1", "url": "https://www.uniprot.org/uniprotkb/F1MSI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGLLNVSWVLSLLCVLQMVETVSGARAPSAGAHISSQFPAAGVSQTSVVDCREVCGLNASDRCAFVRTNPDCRSDGGYLDYLEGIFCHFPARLLPLAITLYAFWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAVSFWSSSGTLEGGPEGVRGWETGDASWPGQPGAPALRPLDTSPHGVTFLAFGNGAPDIFSALVAFSDPRTAGLAFGALFGAGVLVTTVVAGGIAILRPFTAASRPFLRDIIFYMAAVLLIFTALYCGRVTLAWALGYLGFYAFYVVTVVLCTWIYQRQRRRSLVCSMPATPEILSDSEEERMSSNTNSYDYGEEYRPLLLYPETTAQILVQALNPLDYRKWRTKPMYWRVLKVFKLPVEFLLLLTVPVMDPDKEDRNWKRPLNCLHLVISPLFLTLTLQSGAYGVYEIGGLFPVWAAVVIAGTALAAVTFFATSNSEPPRFHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDVFSDFTLARQGYPRMAFSACFGGIIFNMLVGVGLGCLLQISRSHMEVKLEPDGLLVWILAGTLGLSLVCSLVLVPLQCFQLSRVYGCCLLLLYLTFLVVALLTEFGVIHLKTVEEPGDPNPEGGSSQWRGQDQGHVRNLLVRKTR", "length": 660, "header": "tr|A0ABI0NME6-1|A0ABI0NME6_BOVIN Isoform 1 of Mitochondrial sodium/calcium exchanger protein OS=Bos taurus OX=9913 GN=SLC8B1 PE=3 SV=1 CANONICAL=A0ABI0NME6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LSB1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6/entry#A0A3Q1LSB1-1", "sequence": { "sequence": "MAGGLLNVSWVLSLLCVLQMVETVSGARAPSAGAHISSQFPAAGVSQTSVVDCREVCGLNASDRCAFVRTNPDCRSDGGYLDYLEGIFCHFPARLLPLAITLYAFWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAVSFWSSSGTLEGGPEGVRGWETGDASWPGQPGAPALRPLDTSPHGVTFLAFGNGAPDIFSALVAFSDPRTAGLAFGALFGAGVLVTTVVAGGIAILRPFTAASRPFLRDIIFYMAAVLLIFTALYCGRVTLAWALGYLGFYAFYVVTVVLCTWIYQRQRRRSLVCSMPATPEILSDSEEERMSSNTNSYDYGEEYRPLLLYPETTAQILVQALNPLDYRKWRTKPMYWRVLKVFKLPVEFLLLLTVPVMDPDKEDRNWKRPLNCLHLVISPLFLTLTLQSGASLCFPGLPDQRPVDQRGCHRGGEHPAVPGRGIPAEQYCPGAHAAGLGEQHWRCLLRFHAGPSGLPKDGVLGLLRWHHLQYAGGSGAGLPAPDLQEPHGGEAGAGRTVGVDLGGHPGPQPRLFPGFGPTAVLPAEPSLRLLPAPPLPDLPRGGPAH", "length": 577, "header": "tr|A0A3Q1LSB1-1|A0ABI0NME6_BOVIN Computationally mapped isoform of Mitochondrial sodium/calcium exchanger protein OS=Bos taurus OX=9913 GN=SLC8B1 PE=3 SV=2 CANONICAL=A0ABI0NME6-1" }, "locus": { "chromosome": "17", "start_pos": 61315300, "end_pos": 61287708, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070502.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070502.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063230.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063230.2" } ] } }, { "isoform_ac": "A0AAA9TM44-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6/entry#A0AAA9TM44-1", "sequence": { "sequence": "MTVGKNEGTGDQQGPGKSRTAQGLSCFHTDVFSDFTLARQGYPRMAFSACFGGIIFNMLVGVGLGCLLQISRSHMEVKLEPDGLLVWILAGTLGLSLVCSLVLVPLQCFQLSRVYGCCLLLLYLTFLVVALLTEFGVIHLKTV", "length": 143, "header": "tr|A0AAA9TM44-1|A0ABI0NME6_BOVIN Computationally mapped isoform of Mitochondrial sodium/calcium exchanger protein OS=Bos taurus OX=9913 GN=SLC8B1 PE=3 SV=1 CANONICAL=A0ABI0NME6-1" }, "locus": { "chromosome": "17", "start_pos": 61292395, "end_pos": 61287677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097633.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097633.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098056.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098056.1" } ] } }, { "isoform_ac": "A0ABI0NME6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6/entry#A0ABI0NME6-1", "sequence": { "sequence": "MAGGLLNVSWVLSLLCVLQMVETVSGARAPSAGAHISSQFPAAGVSQTSVVDCREVCGLNASDRCAFVRTNPDCRSDGGYLDYLEGIFCHFPARLLPLAITLYAFWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAVSFWSSSGTLEGGPEGVRGWETGDASWPGQPGAPALRPLDTSPHGVTFLAFGNGAPDIFSALVAFSDPRTAGLAFGALFGAGVLVTTVVAGGIAILRPFTAASRPFLRDIIFYMAAVLLIFTALYCGRVTLAWALGYLGFYAFYVVTVVLCTWIYQRQRRRSLVCSMPATPEILSDSEEERMSSNTNSYDYGEEYRPLLLYPETTAQILVQALNPLDYRKWRTKPMYWRVLKVFKLPVEFLLLLTVPVMDPDKEDRNWKRPLNCLHLVISPLFLTLTLQSGAYGVYEIGGLFPVWAAVVIAGTALAAVTFFATSNSEPPRFHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDVFSDFTLARQGYPRMAFSACFGGIIFNMLVGVGLGCLLQISRSHMEVKLEPDGLLVWILAGTLGLSLVCSLVLVPLQCFQLSRVYGCCLLLLYLTFLVVALLTEFGVIHLKTVEEPGDPNPEGGSSQWRGQDQGHVRNLLVRKTR", "length": 660, "header": "tr|A0ABI0NME6-1|A0ABI0NME6_BOVIN Isoform 1 of Mitochondrial sodium/calcium exchanger protein OS=Bos taurus OX=9913 GN=SLC8B1 PE=3 SV=1 CANONICAL=A0ABI0NME6-1" }, "locus": { "chromosome": "17", "start_pos": 61315300, "end_pos": 61275071, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137699.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137699.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106282.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106282.1" } ] } }, { "isoform_ac": "F1MSI3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6/entry#F1MSI3-1", "sequence": { "sequence": "MAGGLLNVSWVLSLLCVLQMVETVSGARAPSAGAHISSQFPAAGVSQTSVVDCREVCGLNASDRCAFVRTNPDCRSDGGYLDYLEGIFCHFPARLLPLAITLYAFWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAVSFWSSSGTLEGGPEGVRGWETGDASWPGQPGAPALRPLDTSPHGVTFLAFGNGAPDIFSALVAFSDPRTAGLAFGALFGAGVLVTTVVAGGIAILRPFTAASRPFLRDIIFYMAAVLLIFTALYCGRVTLAWALGYLGFYAFYVVTVVLCTWIYQRQRRRSLVCSMPATPEILSDSEEERMSSNTNSYDYGEEYRPLLLYPETTAQILVQALNPLDYRKWRTKPMYWRVLKVFKLPVEFLLLLTVPVMDPDKEDRNWKRPLNCLHLVISPLFLTLTLQSGAYGVYEIGGLFPVWAAVVIAGTALAAVTFFATSNSEPPRFHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDVFSDFTLARQGYPRMAFSACFGGIIFNMLVGVGLGCLLQISRSHMEVKLEPDGLLVWILAGTLGLSLVCSLVLVPLQCFQLSRVYGCCLLLLYLTFLVVALLTEFGVIHLKTV", "length": 628, "header": "tr|F1MSI3-1|A0ABI0NME6_BOVIN Computationally mapped isoform of Mitochondrial sodium/calcium exchanger protein OS=Bos taurus OX=9913 GN=SLC8B1 PE=3 SV=3 CANONICAL=A0ABI0NME6-1" }, "locus": { "chromosome": "17", "start_pos": 61315300, "end_pos": 61287677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029532.6", "url": "https://www.ensembl.org/id/ENSBTAT00000029532.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029531.6", "url": "https://www.ensembl.org/id/ENSBTAP00000029531.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-425561", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-425561", "resource": "Reactome", "description": "Sodium/Calcium exchangers" }, { "id": "R-BTA-8949215", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8949215", "resource": "Reactome", "description": "Mitochondrial calcium ion transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NME6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NME6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NME6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6" } ], "pmid": "" }, { "name": "calcium export from the mitochondrion", "id": "GO:0099093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099093", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NME6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6" } ], "pmid": "" }, { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NME6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NME6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium:sodium antiporter activity", "id": "GO:0005432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005432", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NME6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NME6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NME6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "69955", "name": "", "equation": "Ca(2+)(in) + 3 Na(+)(out) = Ca(2+)(out) + 3 Na(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "69955", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69955" } ] }, { "id": "72631", "name": "", "equation": "3 Li(+)(out) + Ca(2+)(in) = 3 Li(+)(in) + Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72631", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72631" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NME6" }, { "id": "PF01699", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01699" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sodium/calcium exchanger membrane region", "eco_id": "ECO_0000259", "start_pos": 182, "end_pos": 289, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"MEEGGKRSDRSSRTSPVHHFRFLPGKAGPSAPTPTRSLRRSQRKSGSDLPNTLPEVCPKAPQEAPVRKPIVLKKIVAHTVEVRAERGVVGGEPGSGVGCVINSSPQIPSINSPRRSPRIASLLEKENNPPSKKLTKEDLFHTCSVPVTAPSTPVLCPVNAESNSWKGDLDARDLEMSKKVRRSYSRLETLGSASTSTPGRQSCFGFEGLLAAEDLAGVSPVVDSKLAEVPRVSVKPWAPDTTLPGISPLVVKEKRKKKKVPEILCPWDGQTAHSEPEEKPAPPPAAEQKSEDTQISGEPDTEPSFSDSSEQQLGQEQEASTTFLFTLLTATEPASDPAEDLDLQESQFLDKEDWGPQRTSKEMSHLQNVCLRLRESLSTIQADNLALGEKLRDLPDSLYKSLKEEAKAILEGEKVIQEEGKAIQEGAQAVQEGALFQVPGTPPSSGWGETTSLPSATQLVPRCLQQPSSQMAGLVILQPDRALNSRNTCQP", "length": 491, "header": "tr|A0ABI0NNS0-1|A0ABI0NNS0_BOVIN Isoform 1 of Cell division cycle associated 5 OS=Bos taurus OX=9913 GN=CDCA5 PE=4 SV=1 CANONICAL=A0ABI0NNS0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TJE4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNS0/entry#A0AAA9TJE4-1", "sequence": { "sequence": "MSERRTRSGGAVQCPGPSAPTPTRSLRRSQRKSGSDLPNTLPEVCPKAPQEAPVRKPIVLKKIVAHTVEIPSINSPRRSPRIASLLEKENNPPSKKLTKEDLFHTCSVPVTAPSTPVLCPVNAESNSWKGDLDARDLEMSKKVRRSYSRLETLGSASTSTPGRQSCFGFEGLLAAEDLAGVSPVVDSKLAEVPRVSVKPWAPDTTLPGISPLVVKEKRKKKKVPEILKSELDEWAAAMNAEFEAAERFDLLVE", "length": 253, "header": "tr|A0AAA9TJE4-1|A0ABI0NNS0_BOVIN Computationally mapped isoform of Cell division cycle associated 5 OS=Bos taurus OX=9913 GN=CDCA5 PE=4 SV=1 CANONICAL=A0ABI0NNS0-1" }, "locus": { "chromosome": "29", "start_pos": 43297147, "end_pos": 43293399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098082.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098082.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098450.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098450.1" } ] } }, { "isoform_ac": "A0ABI0NNS0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNS0/entry#A0ABI0NNS0-1", "sequence": { "sequence": "MEEGGKRSDRSSRTSPVHHFRFLPGKAGPSAPTPTRSLRRSQRKSGSDLPNTLPEVCPKAPQEAPVRKPIVLKKIVAHTVEVRAERGVVGGEPGSGVGCVINSSPQIPSINSPRRSPRIASLLEKENNPPSKKLTKEDLFHTCSVPVTAPSTPVLCPVNAESNSWKGDLDARDLEMSKKVRRSYSRLETLGSASTSTPGRQSCFGFEGLLAAEDLAGVSPVVDSKLAEVPRVSVKPWAPDTTLPGISPLVVKEKRKKKKVPEILCPWDGQTAHSEPEEKPAPPPAAEQKSEDTQISGEPDTEPSFSDSSEQQLGQEQEASTTFLFTLLTATEPASDPAEDLDLQESQFLDKEDWGPQRTSKEMSHLQNVCLRLRESLSTIQADNLALGEKLRDLPDSLYKSLKEEAKAILEGEKVIQEEGKAIQEGAQAVQEGALFQVPGTPPSSGWGETTSLPSATQLVPRCLQQPSSQMAGLVILQPDRALNSRNTCQP", "length": 491, "header": "tr|A0ABI0NNS0-1|A0ABI0NNS0_BOVIN Isoform 1 of Cell division cycle associated 5 OS=Bos taurus OX=9913 GN=CDCA5 PE=4 SV=1 CANONICAL=A0ABI0NNS0-1" }, "locus": { "chromosome": "29", "start_pos": 43297312, "end_pos": 43280550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142141.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142141.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107396.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107396.1" } ] } }, { "isoform_ac": "A0ABI0P224-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNS0/entry#A0ABI0P224-1", "sequence": { "sequence": "MSERRTRSGGAVQCPGPSAPTPTRSLRRSQRKSGSDLPNTLPEVCPKAPQEAPVRKPIVLKKIVAHTVEVRAERGVVGGEPGSGVGCVINSSPQIPSINSPRRSPRIASLLEKENNPPSKKLTKEDLFHTCSVPVTAPSTPVLCPVNAESNSWKGDLDARDLEMSKKVRRSYSRLETLGSASTSTPGRQSCFGFEGLLAAEDLAGVSPVVDSKLAEVPRVSVKPWAPDTTLPGISPLVVKEKRKKKKVPEILCPWDGQTAHSEPEEKPAPPPAAEQKSEDTQISGEPDTEPSFSDSSEQQLGQEQEASTTFLFTLLTATEPASDPAEDLDLQESQFLDKEDWGPQRTSKEMSHLQNVCLRLRESLSTIQADNLALGEKLRDLPDSLYKSLKEEAKAILEGEKVIQEEGKAIQEGAQAVQEGALFQVPGTPPSSGWGETTSLPSATQLVPRCLQQPSSQMAGLVILQPDRALNSRNTCQP", "length": 479, "header": "tr|A0ABI0P224-1|A0ABI0P224_BOVIN Computationally mapped isoform of Cell division cycle associated 5 OS=Bos taurus OX=9913 GN=CDCA5 PE=4 SV=1 CANONICAL=A0ABI0NNS0-1" }, "locus": { "chromosome": "29", "start_pos": 43297147, "end_pos": 43280550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140273.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140273.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104821.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104821.1" } ] } }, { "isoform_ac": "A0ABI0P2R7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNS0/entry#A0ABI0P2R7-1", "sequence": { "sequence": "MSERRTRSGGAVQCPGPSAPTPTRSLRRSQRKSGSDLPNTLPEVCPKAPQEAPVRKPIVLKKIVAHTVEVRAERGVVGGEPGSGVGCVINSSPQIPSINSPRRSPRIASLLEKENNPPSKKLTKEDLFHTCSVPVTAPSTPVLCPVNAESNSWKGDLDARDLEMSKKVRRSYSRLETLGSASTSTPGRQSCFGFEGLLAAEDLAGVSPVVDSKLAEVPRVSVKPWAPDTTLPGISPLVVKEKRKKKKVPEILCPWDGQTAHSEPEEKPAPPPAAEQKSEDTQISGEPDTEPSFSDSSEQQLGQEQEASTTFLFTLLTATEPASDPAEDLDLQESQFLDKEDWGPQRTSKEMSHLQNVCLRLRESLSTIQADNLALGEKLRDLPDSLYKSLKEEAKAILEGEKVIQEEATQLPDGRTGHPAA", "length": 421, "header": "tr|A0ABI0P2R7-1|A0ABI0P2R7_BOVIN Computationally mapped isoform of Cell division cycle associated 5 OS=Bos taurus OX=9913 GN=CDCA5 PE=4 SV=1 CANONICAL=A0ABI0NNS0-1" }, "locus": { "chromosome": "29", "start_pos": 43297147, "end_pos": 43280587, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153003.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153003.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105379.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105379.1" } ] } }, { "isoform_ac": "F1MWW9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNS0/entry#F1MWW9-1", "sequence": { "sequence": "MEEGGKRSDRSSRTSPVHHFRFLPGKAGPSAPTPTRSLRRSQRKSGSDLPNTLPEVCPKAPQEAPVRKPIVLKKIVAHTVEVRAERGVVGGEPGSGVGCVINSSPQIPSINSPRRSPRIASLLEKENNPPSKKLTKEDLFHTCSVPVTAPSTPVLCPVNAESNSWKGDLDARDLEMSKKVRRSYSRLETLGSASTSTPGRQSCFGFEGLLAAEDLAGVSPVVDSKLAEVPRVSVKPWAPDTTLPGISPLVVKEKRKKKKVPEILKSELDEWAAAMNAEFEAAERFDLLVE", "length": 290, "header": "tr|F1MWW9-1|A0ABI0NNS0_BOVIN Computationally mapped isoform of Cell division cycle associated 5 OS=Bos taurus OX=9913 GN=CDCA5 PE=4 SV=4 CANONICAL=A0ABI0NNS0-1" }, "locus": { "chromosome": "29", "start_pos": 43297312, "end_pos": 43293399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045602.4", "url": "https://www.ensembl.org/id/ENSBTAT00000045602.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042980.4", "url": "https://www.ensembl.org/id/ENSBTAP00000042980.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 197, "start_aa": "Thr", "end_pos": 197, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr197", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 33, "start_aa": "Thr", "end_pos": 33, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr33", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-BTA-2468052", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2468052", "resource": "Reactome", "description": "Establishment of Sister Chromatid Cohesion" }, { "id": "R-BTA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNS0" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNS0" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNS0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNS0" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNS0" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NNS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNS0" }, { "id": "PF09666", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09666" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sororin-like middle region", "eco_id": "ECO_0000259", "start_pos": 126, "end_pos": 253, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 33, 197 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": 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"count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { 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"reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SULT1C2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTS0", "locus": { "chromosome": "11", "start_pos": 44885143, "end_pos": 44905259, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038369", "url": "https://www.ensembl.org/id/ENSBTAG00000038369" } ] } } ], "crossref": [ { "id": "ENSBTAG00000038369", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038369", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "523898", "url": "https://www.ncbi.nlm.nih.gov/gene/523898", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523898", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523898", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1MBP4", "url": "https://www.orthodb.org/?gene=F1MBP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11783", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11783", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-156584", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156584", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005212788", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212788", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "70607", "url": "https://www.rhea-db.org/rhea/70607", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NTS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTS0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NY70", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NY70-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MBP4", "url": "https://www.uniprot.org/uniprotkb/F1MBP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MBP4-1", "url": "https://www.uniprot.org/uniprotkb/F1MBP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGGQSLDKEAVSGPGGSSAEHEPTCLEERPKVTGPPAARPQLSSDGLRHAQVSLCQTRTQSPVCSPGDANWTAISSPDPMALTTAGTQPSLGEVAGIPLPATTVDNWHQIQGFEAQPDDLLICTYPKSGTTWIQEIVDLIEHSGDVDKCQRAAIQHRHPFLEWARPPQPSGVEKARAMPRPRVLRTHFPAQLLPPSFWESNCKFLYVARNAKDCLVSYYHFQRMNRTLPDPGTWDQYFETFISGKVAWGSWFEHVRGWWELRDNVQMLFLFYEDIKRDPKQEIQKVMKFMEKNLDGAVLDTIVQETTFEKMKANPMTNRSTAPKTILDQSISPFMRKGIVGDWKNHFTVAQNERFDEIYRQKMKGTSINFCTEL", "length": 375, "header": "tr|A0ABI0NTS0-1|A0ABI0NTS0_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=SULT1C2 PE=3 SV=1 CANONICAL=A0ABI0NTS0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NTS0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTS0/entry#A0ABI0NTS0-1", "sequence": { "sequence": "MRGGQSLDKEAVSGPGGSSAEHEPTCLEERPKVTGPPAARPQLSSDGLRHAQVSLCQTRTQSPVCSPGDANWTAISSPDPMALTTAGTQPSLGEVAGIPLPATTVDNWHQIQGFEAQPDDLLICTYPKSGTTWIQEIVDLIEHSGDVDKCQRAAIQHRHPFLEWARPPQPSGVEKARAMPRPRVLRTHFPAQLLPPSFWESNCKFLYVARNAKDCLVSYYHFQRMNRTLPDPGTWDQYFETFISGKVAWGSWFEHVRGWWELRDNVQMLFLFYEDIKRDPKQEIQKVMKFMEKNLDGAVLDTIVQETTFEKMKANPMTNRSTAPKTILDQSISPFMRKGIVGDWKNHFTVAQNERFDEIYRQKMKGTSINFCTEL", "length": 375, "header": "tr|A0ABI0NTS0-1|A0ABI0NTS0_BOVIN Isoform 1 of Sulfotransferase OS=Bos taurus OX=9913 GN=SULT1C2 PE=3 SV=1 CANONICAL=A0ABI0NTS0-1" }, "locus": { "chromosome": "11", "start_pos": 44899476, "end_pos": 44885320, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146690.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146690.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106832.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106832.1" } ] } }, { "isoform_ac": "A0ABI0NY70-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTS0/entry#A0ABI0NY70-1", "sequence": { "sequence": "MRGGQSLDKEAVSGPGGSSAEHEPTCLEERPKVTGPPAARPQLSSDGLRHAQVSLCQTRTQSPVCSPGDANWTAISSPDPMALTTAGTQPSLGEVAGIPLPATTVDNWHQIQGFEAQPDDLLICTYPKSGTTWIQEIVDLIEHSGDVDKCQRAAIQHRHPFLEWARPPQPSGVEKARAMPRPRVLRTHFPAQLLPPSFWESNCKFLYVARNAKDCLVSYYHFQRMNRTLPDPGTWDQYFETFISGKVAWGSWFEHVRGWWELRDNVQMLFLFYEDIKRDPKQEIQKVMKFMEKNLDGAVLDTIVQETTFEKMKANPMTNRSTAPKTILDQSISPFMRKVYNSFPVTETSQANPLLSLGSLRNRGGLEKPLHGGSE", "length": 375, "header": "tr|A0ABI0NY70-1|A0ABI0NY70_BOVIN Computationally mapped isoform of Sulfotransferase OS=Bos taurus OX=9913 GN=SULT1C2 PE=3 SV=1 CANONICAL=A0ABI0NTS0-1" }, "locus": { "chromosome": "11", "start_pos": 44899476, "end_pos": 44885387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151018.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151018.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105925.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105925.1" } ] } }, { "isoform_ac": "F1MBP4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTS0/entry#F1MBP4-1", "sequence": { "sequence": "MSDSLQPHGLHSTRLLSPWDFPGTAISSPDPMALTTAGTQPSLGEVAGIPLPATTVDNWHQIQGFEAQPDDLLICTYPKSGTTWIQEIVDLIEHSGDVDKCQRAAIQHRHPFLEWARPPQPSGVEKARAMPRPRVLRTHFPAQLLPPSFWESNCKRMNRTLPDPGTWDQYFETFISGKVAWGSWFEHVRGWWELRDNVQMLFLFYEDIKRDPKQEIQKVMKFMEKNLDGAVLDTIVQETTFEKMKANPMTNRSTAPKTILDQSISPFMRKGIVGDWKNHFTVAQNERFDEIYRQKMKGTSINFCTEL", "length": 307, "header": "tr|F1MBP4-1|A0ABI0NTS0_BOVIN Computationally mapped isoform of Sulfotransferase OS=Bos taurus OX=9913 GN=SULT1C2 PE=3 SV=3 CANONICAL=A0ABI0NTS0-1" }, "locus": { "chromosome": "11", "start_pos": 44905216, "end_pos": 44885320, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003629.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003629.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003629.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003629.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:523898", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523898", "resource": "KEGG Pathway" }, { "id": "R-BTA-156584", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156584", "resource": "Reactome", "description": "Cytosolic sulfonation of small molecules" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sulfation", "id": "GO:0051923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051923", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTS0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "aryl sulfotransferase activity", "id": "GO:0004062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004062", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTS0" } ], "pmid": "" }, { "name": "sulfotransferase activity", "id": "GO:0008146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008146", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTS0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "70607", "name": "", "equation": "4-ethylphenol + 3'-phosphoadenylyl sulfate = 4-ethylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3T0Y3-1", "P50227-1", "P19217-1", "A0AAA9RW31-1", "A0A3Q1N4J6-1", "F1MZX9-1", "E1BG19-1", "E1BAC7-1", "E1BIS9-1", "A0ABI0NTS0-1", "A0AAA9SGU9-1", "A0ABI0P531-1", "E1BJ78-1" ], "evidence": [ { "id": "70607", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70607" } ] }, { "id": "R-BTA-176474", "name": "3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-176486" ], "output_participant_list": [ "R-ALL-176519" ], "enzyme_list": [ "Q3T0Y3-1", "P50227-1", "F1MZX9-1", "E1BG19-1", "A0ABI0NTS0-1" ], "evidence": [ { "id": "R-BTA-176474", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176474" } ] }, { "id": "R-BTA-176585", "name": "3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-176667" ], "output_participant_list": [ "R-ALL-176564" ], "enzyme_list": [ "Q3T0Y3-1", "P50227-1", "F1MZX9-1", "E1BG19-1", "A0ABI0NTS0-1" ], "evidence": [ { "id": "R-BTA-176585", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176585" } ] }, { "id": "R-BTA-176669", "name": "N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-176566" ], "output_participant_list": [ "R-ALL-176500" ], "enzyme_list": [ "P50227-1", "A0AAA9RW31-1", "A0ABI0NTS0-1" ], "evidence": [ { "id": "R-BTA-176669", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176669" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-176486", "participant_name": "3,3'-diiodothyronine [cytosol]", "crossref": [ { "id": "35430", "database": "ChEBI", "url": "" }, { "id": "11533682", "database": "PubChem Substance", "url": "" }, { "id": "ZINC000016051523", "database": "ZINC", "url": "" }, { "id": "ZINC000045331653", "database": "ZINC", "url": "" }, { "id": "HMDB0005869", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-176500", "participant_name": "AAF-N-S [cytosol]", "crossref": [ { "id": "11533684", "database": "PubChem Substance", "url": "" }, { "id": "ZINC000002018271", "database": "ZINC", "url": "" }, { "id": "35424", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-176519", "participant_name": "3,3'-diiodothyronine 4-sulfate [cytosol]", "crossref": [ { "id": "35431", "database": "ChEBI", "url": "" }, { "id": "ZINC000031706818", "database": "ZINC", "url": "" }, { "id": "11533681", "database": "PubChem Substance", "url": "" } ] }, { "participant_id": "R-ALL-176564", "participant_name": "3,5,3'-triiodothyronine 4-sulfate [cytosol]", "crossref": [ { "id": "ZINC000085552312", "database": "ZINC", "url": "" }, { "id": "35432", "database": "ChEBI", "url": "" }, { "id": "HMDB0003036", "database": "HMDB Metabolite", "url": "" }, { "id": "11533680", "database": "PubChem Substance", "url": "" } ] }, { "participant_id": "R-ALL-176566", "participant_name": "N-hydroxy-2-acetylaminofluorene [cytosol]", "crossref": [ { "id": "17931", "database": "ChEBI", "url": "" }, { "id": "8145202", "database": "PubChem Substance", "url": "" }, { "id": "ZINC000005196784", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-176667", "participant_name": "T3 [cytosol]", "crossref": [ { "id": "533015", "database": "ChEBI", "url": "" }, { "id": "ZINC000003830999", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1N4J6", "gene_name": "", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A3Q1N4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4J6" } ] } ] }, { "uniprot_ac": "A0AAA9RW31", "gene_name": "LOC100300896", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0AAA9RW31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW31" } ] } ] }, { "uniprot_ac": "A0AAA9SGU9", "gene_name": "LOC514658", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0AAA9SGU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGU9" } ] } ] }, { "uniprot_ac": "A0ABI0NTS0", "gene_name": "SULT1C2", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0ABI0NTS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTS0" } ] } ] }, { "uniprot_ac": "A0ABI0P531", "gene_name": "LOC112446736", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0ABI0P531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P531" } ] } ] }, { "uniprot_ac": "E1BAC7", "gene_name": "SULT1D1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BAC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAC7" } ] } ] }, { "uniprot_ac": "E1BG19", "gene_name": "SULT2A1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BG19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG19" } ] } ] }, { "uniprot_ac": "E1BIS9", "gene_name": "SULT1C3", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIS9" } ] } ] }, { "uniprot_ac": "E1BJ78", "gene_name": "LOC783020", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "E1BJ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ78" } ] } ] }, { "uniprot_ac": "F1MZX9", "gene_name": "SULT6B1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "F1MZX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MZX9" } ] } ] }, { "uniprot_ac": "P19217", "gene_name": "SULT1E1", "activity": [ { "ec_number": "2.8.2.4", "activity": "estrone + 3'-phosphoadenylyl sulfate = estrone 3-sulfate + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "P19217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19217" } ] }, { "ec_number": "2.8.2.4", "activity": "", "evidence": [ { "id": "P19217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19217" } ] } ] }, { "uniprot_ac": "P50227", "gene_name": "SULT1A1", "activity": [ { "ec_number": "2.8.2.1", "activity": "a phenol + 3'-phosphoadenylyl sulfate = an aryl sulfate + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "P50227", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50227" } ] }, { "ec_number": "2.8.2.1", "activity": "", "evidence": [ { "id": "P50227", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50227" } ] } ] }, { "uniprot_ac": "Q3T0Y3", "gene_name": "SULT1B1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "Q3T0Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0Y3" } ] }, { "ec_number": "2.8.2.1", "activity": "a phenol + 3'-phosphoadenylyl sulfate = an aryl sulfate + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "Q3T0Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0Y3" } ] }, { "ec_number": "2.8.2.1", "activity": "", "evidence": [ { "id": "Q3T0Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0Y3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NTS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTS0" }, { "id": "PF00685", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfotransferase", "eco_id": "ECO_0000259", "start_pos": 118, "end_pos": 367, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 226, "end_pos": 228 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NTX6-1", "uniprot_ac": "A0ABI0NTX6", "uniprot_id": "A0ABI0NTX6_BOVIN", "mass": { "chemical_mass": 260448.0, "monoisotopic_mass": 260448.0 }, "refseq": {}, "gene_names": [ { "name": "NAV2", "type": "recommended", "evidence": [ { "id": "A0ABI0NTX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6" } ] } ], "protein_names": [ { "name": "Neuron navigator 2", "type": "recommended", "evidence": [ { "id": "A0ABI0NTX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Possesses 3' to 5' helicase activity and exonuclease activity. Involved in cytoskeleton organization. Required for neurite outgrowth in response to stimulation by all-trans retinoic acid (atRA). Involved in neuronal development, specifically in the development of different sensory organs. Important for brain and cerebellar development. Involved in the differentiation, migration and axonal extension of granule cells in the developing cerebellum. Involved in the development of the glossopharyngeal cranial nerve IX and the vagus cranial nerve X, possibly by influencing neuronal cell elongation or survival; influencing the efficiency of the baroreceptor reflex response to changes in blood pressure.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NN43", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN43#function" }, { "database": "UniProtKB", "id": "ARBA00094132", "url": "https://www.uniprot.org/uniprotkb/ARBA00094132#function" }, { "database": "UniProtKB", "id": "A0ABI0NN88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN88#function" }, { "database": "UniProtKB", "id": "A0ABI0NTX6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6#function" }, { "database": "UniProtKB", "id": "A0ABI0P087", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P087#function" }, { "database": "UniProtKB", "id": "A0ABI0P3W1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3W1#function" }, { "database": "UniProtKB", "id": "A0ABI0P6R1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6R1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTX6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NAV2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6", "locus": { "chromosome": "29", "start_pos": 24803309, "end_pos": 24891528, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018431", "url": "https://www.ensembl.org/id/ENSBTAG00000018431" } ] } } ], "crossref": [ { "id": "ENSBTAG00000018431", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018431", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21285", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21285", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100139508", "url": "https://www.ncbi.nlm.nih.gov/gene/100139508", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100139508", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100139508", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1MHF3", "url": "https://www.orthodb.org/?gene=F1MHF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12784", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12784", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12784:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12784:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25408", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25408", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NN43", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NN43-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NN88", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NN88-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTX6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTX6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P087", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P087", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P087-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P087-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3W1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3W1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3W1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6R1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6R1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MHF3", "url": "https://www.uniprot.org/uniprotkb/F1MHF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MHF3-1", "url": "https://www.uniprot.org/uniprotkb/F1MHF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTAYPSQIPLKSQGLQEPAGEGLPLRMSGSVENGFDTQIYTDWANHYLAKSGHKRLIKDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQQPPPPQKPHLPSPLPPPGSQVAGAPSQCQAGPPQQQVPATPQAPCQPHQPAPHQPSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSATANNRRSQSFNNYDKSKPVTSPPPPSSSHEKEPLASPASSHPAMSEDAPAALEGGGGCGPASCGASSAIPQPGSASKPWRSKSVSVKHSAAAAALSVKPPTPEPPRPAPEALKPAPNNQRSMLEKLKLFNSKGASKAGEGPGSRDTSCERLEILPSFEESEEMEAGGRPLSAAGPPSNSPKIALKGIAQRTFSRALTNKKSSPKGSEKEKEKQQREKEKSKDLTKRASVTERPDLREGPREDPSGAALTEMPKKSSKIASFIPKGGKLNSAKKEAPAPSHSGIPKPGMKSVPGKSPSAPTPSKDGERARGGKPSSGLPQQKPPLDGRHSSSSSSLASSEGKGPGGTGLNHSISSQTVSASVGTTQTTGSNTVSVQLPQPQQQYSHPNTATVAPFLYRSQTDTEGNVTAESSSGGVTMEPSHYTKSGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEISGRSILSLTGRPTPLAWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEAISMDAPGYMSDGDVLSKNMRADDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERSSLWSSEDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPAAPTGTLKTPGTGKTDDAKVSEKGRLSPKAAQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGATVTSRSATLGKIPKSSALVGRSTGRKTSMDGAQNQDDGYLSLSSRTNLQYRSLPRPSKSTSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAPQPVSSVAQATLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATLSQQGNLESPSGSGVLSSGSSSPLYSKNVDSTQSPLASSPSSAHSGPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGALSHNSSTGLIAASKDDALTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTTANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDTRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSIYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGSSQATDLRIRRQHSSDSVSSINSATSHSSVGSNIETDSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSLSASPRQSLGLSQHSLNLAESSSLDMLLDDAGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHIDPVSQLGLNSDSVLGYSIGDVKRSNTSETPELLPCGYLVGENTTISVAVKGLAENSLDSLVFESLIPKPILQRYVSLLVEHRRIILSGPSGTGKTYLANRLSEYLVLREGRELTDGVVATFNVDHKSSKELRQYLSNLADQCASENNAMDMPLVIILDNLHHVSSLGEIFNGLLNCKDHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRMRNVELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSAAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSTSHQDDILDSSLESTL", "length": 2431, "header": "tr|A0ABI0NTX6-1|A0ABI0NTX6_BOVIN Isoform 1 of Neuron navigator 2 OS=Bos taurus OX=9913 GN=NAV2 PE=3 SV=1 CANONICAL=A0ABI0NTX6-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NN43-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6/entry#A0ABI0NN43-1", "sequence": { "sequence": "MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTAYPSQIPLKSQGLQEPAGEGLPLRMSGSVENGFDTQIYTDWANHYLAKSGHKRLIKDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQQPPPPQKPHLPSPLPPPGSQVAGAPSQCQAGPPQQQVPATPQAPCQPHQPAPHQPSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSATANNRRSQSFNNYDKSKPVTSPPPPSSSHEKEPLASPASSHPAMSEDAPAALEGGGGCGPASCGASSAIPQPGSASKPWRSKSVSVKHSAAAAALSVKPPTPEPPRPAPEALKPAPNNQRSMLEKLKLFNSKGASKAGEGPGSRDTSCERLEILPSFEESEEMEAGGRPLSAAGPPSNSPKIALKGIAQRTFSRALTNKKSSPKGSEKEKEKQQREKEKSKDLTKRASVTERPDLREGPREDPSGAALTEMPKKSSKIASFIPKGGKLNSAKKEAPAPSHSGIPKPGMKSVPGKSPSAPTPSKDGERARGGKPSSGLPQQKPPLDGRHSSSSSSLASSEGKGPGGTGLNHSISSQTVSASVGTTQTTGSNTVSVQLPQPQQQYSHPNTATVAPFLYRSQTDTEGNVTAESSSGGVTMEPSHYTKSGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEISGRSILSLTGRPTPLAWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEAISMDAPGYMSDGDVLSKNMRADDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERSSLWSSEDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPAAPTGTLKTPGTGKTDDAKVSEKGRLSPKAAQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGATVTSRSATLGKIPKSSALVGRSTGRKTSMDGAQNQDDGYLSLSSRTNLQYRSLPRPSKSTSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAPQPVSSVAQATLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATLSQQGNLESPSGSGVLSSGSSSPLYSKNVDSTQSPLASSPSSAHSGPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGALSHNSSTGLIAASKDDALTPFVRTNSVKTTLSERYTPTSQLRTQEDAKEWLRSHSAGGLQDTTANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDTRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSIYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGSSQATDLRIRRQHSSDSVSSINSATSHSSVGSNIETDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSLSASPRQSLGLSQHSLNLAESSSLDMLLDDAGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHIDPVSQLGLNSDSVLGYSIGDVKRSNTSETPELLPCGYLVGENTTISVAVKGLAENSLDSLVFESLIPKPILQRYVSLLVEHRRIILSGPSGTGKTYLANRLSEYLVLREGRELTDGVVATFNVDHKSSKELRQYLSNLADQCASENNAMDMPLVIILDNLHHVSSLGEIFNGLLNCKDHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRMRNVELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSAAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSTSHQDDILDSSLESTL", "length": 2391, "header": "tr|A0ABI0NN43-1|A0ABI0NN43_BOVIN Computationally mapped isoform of Neuron navigator 2 OS=Bos taurus OX=9913 GN=NAV2 PE=3 SV=1 CANONICAL=A0ABI0NTX6-1" }, "locus": { "chromosome": "29", "start_pos": 25224098, "end_pos": 24804313, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139598.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139598.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107019.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107019.1" } ] } }, { "isoform_ac": "A0ABI0NN88-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6/entry#A0ABI0NN88-1", "sequence": { "sequence": "MESVSESSQQQKRKLVTHGLEDQKRIYTDWANHYLAKSGHKRLIKDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQQPPPPQKPHLPSPLPPPGSQVAGAPSQCQAGPPQQQVPATPQAPCQPHQPAPHQPSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSATANNRRSQSFNNYDKSKPVTSPPPPSSSHEKEPLASPASSHPAMSEDAPAALEGGGGCGPASCGASSAIPQPGSASKPWRSKSVSVKHSAAAAALSVKPPTPEPPRPAPEALKPAPNNQRSMLEKLKLFNSKGASKAGEGPGSRDTSCERLEILPSFEESEEMEAGGRPLSAAGPPSNSPKIALKGIAQRTFSRALTNKKSSPKGSEKEKEKQQREKEKSKDLTKRASVTERPDLREGPREDPSGAALTEMPKKSSKIASFIPKGGKLNSAKKEAPAPSHSGIPKPGMKSVPGKSPSAPTPSKDGERARGGKPSSGLPQQKPPLDGRHSSSSSSLASSEGKGPGGTGLNHSISSQTVSASVGTTQTTGSNTVSVQLPQPQQQYSHPNTATVAPFLYRSQTDTEGNVTAESSSGGVTMEPSHYTKSGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEISGRSILSLTGRPTPLAWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEAISMDAPGYMSDGDVLSKNMRADDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERSSLWSSEDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPAAPTGTLKTPGTGKTDDAKVSEKGRLSPKAAQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGATVTSRSATLGKIPKSSALVGRSTGRKTSMDGAQNQDDGYLSLSSRTNLQYRSLPRPSKSTSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAPQPVSSVAQATLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATLSQQGNLESPSGSGVLSSGSSSPLYSKNVDSTQSPLASSPSSAHSGPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGALSHNSSTGLIAASKDDALTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTTANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDTRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSIYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGSSQATDLRIRRQHSSDSVSSINSATSHSSVGSNIETDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSLSASPRQSLGLSQHSLNLAESSSLDMLLDDAGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHIDPVSQLGLNSDSVLGYSIGDVKRSNTSETPELLPCGYLVGENTTISVAVKGLAENSLDSLVFESLIPKPILQRYVSLLVEHRRIILSGPSGTGKTYLANRLSEYLVLREGRELTDGVVATFNVDHKSSKELRQYLSNLADQCASENNAMDMPLVIILDNLHHVSSLGEIFNGLLNCKDHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRMRNVELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSAAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSTSHQDDILDSSLESTL", "length": 2367, "header": "tr|A0ABI0NN88-1|A0ABI0NN88_BOVIN Computationally mapped isoform of Neuron navigator 2 OS=Bos taurus OX=9913 GN=NAV2 PE=3 SV=1 CANONICAL=A0ABI0NTX6-1" }, "locus": { "chromosome": "29", "start_pos": 25591514, "end_pos": 24804313, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150137.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150137.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106758.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106758.1" } ] } }, { "isoform_ac": "A0ABI0NTX6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6/entry#A0ABI0NTX6-1", "sequence": { "sequence": "MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTAYPSQIPLKSQGLQEPAGEGLPLRMSGSVENGFDTQIYTDWANHYLAKSGHKRLIKDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQQPPPPQKPHLPSPLPPPGSQVAGAPSQCQAGPPQQQVPATPQAPCQPHQPAPHQPSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSATANNRRSQSFNNYDKSKPVTSPPPPSSSHEKEPLASPASSHPAMSEDAPAALEGGGGCGPASCGASSAIPQPGSASKPWRSKSVSVKHSAAAAALSVKPPTPEPPRPAPEALKPAPNNQRSMLEKLKLFNSKGASKAGEGPGSRDTSCERLEILPSFEESEEMEAGGRPLSAAGPPSNSPKIALKGIAQRTFSRALTNKKSSPKGSEKEKEKQQREKEKSKDLTKRASVTERPDLREGPREDPSGAALTEMPKKSSKIASFIPKGGKLNSAKKEAPAPSHSGIPKPGMKSVPGKSPSAPTPSKDGERARGGKPSSGLPQQKPPLDGRHSSSSSSLASSEGKGPGGTGLNHSISSQTVSASVGTTQTTGSNTVSVQLPQPQQQYSHPNTATVAPFLYRSQTDTEGNVTAESSSGGVTMEPSHYTKSGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEISGRSILSLTGRPTPLAWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEAISMDAPGYMSDGDVLSKNMRADDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERSSLWSSEDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPAAPTGTLKTPGTGKTDDAKVSEKGRLSPKAAQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGATVTSRSATLGKIPKSSALVGRSTGRKTSMDGAQNQDDGYLSLSSRTNLQYRSLPRPSKSTSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAPQPVSSVAQATLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATLSQQGNLESPSGSGVLSSGSSSPLYSKNVDSTQSPLASSPSSAHSGPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGALSHNSSTGLIAASKDDALTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTTANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDTRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSIYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGSSQATDLRIRRQHSSDSVSSINSATSHSSVGSNIETDSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSLSASPRQSLGLSQHSLNLAESSSLDMLLDDAGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHIDPVSQLGLNSDSVLGYSIGDVKRSNTSETPELLPCGYLVGENTTISVAVKGLAENSLDSLVFESLIPKPILQRYVSLLVEHRRIILSGPSGTGKTYLANRLSEYLVLREGRELTDGVVATFNVDHKSSKELRQYLSNLADQCASENNAMDMPLVIILDNLHHVSSLGEIFNGLLNCKDHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRMRNVELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSAAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSTSHQDDILDSSLESTL", "length": 2431, "header": "tr|A0ABI0NTX6-1|A0ABI0NTX6_BOVIN Isoform 1 of Neuron navigator 2 OS=Bos taurus OX=9913 GN=NAV2 PE=3 SV=1 CANONICAL=A0ABI0NTX6-1" }, "locus": { "chromosome": "29", "start_pos": 25224098, "end_pos": 24804313, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145794.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145794.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107116.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107116.1" } ] } }, { "isoform_ac": "A0ABI0P087-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6/entry#A0ABI0P087-1", "sequence": { "sequence": "MSVMLWRWDQNNTTMKLIYTDWANHYLAKSGHKRLIKDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQQPPPPQKPHLPSPLPPPGSQVAGAPSQCQAGPPQQQVPATPQAPCQPHQPAPHQPSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSATANNRRSQSFNNYDKSKPVTSPPPPSSSHEKEPLASPASSHPAMSEDAPAALEGGGGCGPASCGASSAIPQPGSASKPWRSKSVSVKHSAAAAALSVKPPTPEPPRPAPEALKPAPNNQRSMLEKLKLFNSKGASKAGEGPGSRDTSCERLEILPSFEESEEMEAGGRPLSAAGPPSNSPKIALKGIAQRTFSRALTNKKSSPKGSEKEKEKQQREKEKSKDLTKRASVTERPDLREGPREDPSGAALTEMPKKSSKIASFIPKGGKLNSAKKEAPAPSHSGIPKPGMKSVPGKSPSAPTPSKDGERARGGKPSSGLPQQKPPLDGRHSSSSSSLASSEGKGPGGTGLNHSISSQTVSASVGTTQTTGSNTVSVQLPQPQQQYSHPNTATVAPFLYRSQTDTEGNVTAESSSGGVTMEPSHYTKSGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEISGRSILSLTGRPTPLAWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEAISMDAPGYMSDGDVLSKNMRADDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERSSLWSSEDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPAAPTGTLKTPGTGKTDDAKVSEKGRLSPKAAQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGATVTSRSATLGKIPKSSALVGRSTGRKTSMDGAQNQDDGYLSLSSRTNLQYRSLPRPSKSTSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAPQPVSSVAQATLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATLSQQGNLESPSGSGVLSSGSSSPLYSKNVDSTQSPLASSPSSAHSGPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGALSHNSSTGLIAASKDDALTPFVRTNSVKTTLSERYTPTSQLRTQEDAKEWLRSHSAGGLQDTTANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDTRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSIYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGSSQATDLRIRRQHSSDSVSSINSATSHSSVGSNIETDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSLSASPRQSLGLSQHSLNLAESSSLDMLLDDAGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHIDPVSQLGLNSDSVLGYSIGDVKRSNTSETPELLPCGYLVGENTTISVAVKGLAENSLDSLVFESLIPKPILQRYVSLLVEHRRIILSGPSGTGKTYLANRLSEYLVLREGRELTDGVVATFNVDHKSSKELRQYLSNLADQCASENNAMDMPLVIILDNLHHVSSLGEIFNGLLNCKDHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRMRNVELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSAAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSTSHQDDILDSSLESTL", "length": 2322, "header": "tr|A0ABI0P087-1|A0ABI0P087_BOVIN Computationally mapped isoform of Neuron navigator 2 OS=Bos taurus OX=9913 GN=NAV2 PE=3 SV=1 CANONICAL=A0ABI0NTX6-1" }, "locus": { "chromosome": "29", "start_pos": 25152644, "end_pos": 24804313, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153593.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153593.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104167.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104167.1" } ] } }, { "isoform_ac": "A0ABI0P3W1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6/entry#A0ABI0P3W1-1", "sequence": { "sequence": "MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTAYPSQIPLKSQGLQEPAGEGLPLRMSGSVENGFDTQIYTDWANHYLAKSGHKRLIKDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQQPPPPQKPHLPSPLPPPGSQVAGAPSQCQAGPPQQQVPATPQAPCQPHQPAPHQPSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSATANNRRSQSFNNYDKSKPVTSPPPPSSSHEKEPLASPASSHPAMSEDAPAALEGGGGCGPASCGASSAIPQPGSASKPWRSKSVSVKHSAAAAALSVKPPTPEPPRPAPEALKPAPNNQRSMLEKLKLFNSKGASKAGEGPGSRDTSCERLEILPSFEESEEMEAGGRPLSAAGPPSNSPKIALKGIAQRTFSRALTNKKSSPKGSEKEKEKQQREKEKSKDLTKRASVTERPDLREGPREDPSGAALTEMPKKSSKIASFIPKGGKLNSAKKEAPAPSHSGIPKPGMKSVPGKSPSAPTPSKDGERARGGKPSSGLPQQKPPLDGRHSSSSSSLASSEGKGPGGTGLNHSISSQTVSASVGTTQTTGSNTVSVQLPQPQQQYSHPNTATVAPFLYRSQTDTEGNVTAESSSGGVTMEPSHYTKSGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEISGRSILSLTGRPTPLAWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEAISMDAPGYMSDGDVLSKNMRADDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERSSLWSSEDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPAAPTGTLKTPGTGKTDDAKVSEKGRLSPKAAQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGATVTSRSATLGKIPKSSALVGRSTGRKTSMDGAQNQDDGYLSLSSRTNLQYRSLPRPSKSTSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAPQPVSSVAQATLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATLSQQGNLESPSGSGVLSSGSSSPLYSKNVDSTQSPLASSPSSAHSGPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGALSHNSSTGLIAASKDDALTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTTANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDTRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSIYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGSSQATDLRIRRQHSSDSVSSINSATSHSSVGSNIETDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSLSASPRQSLGLSQHSLNLAESSSLDMLLDDAGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHIDPVSQLGLNSDSVLGYSIGDVKRSNTSETPELLPCGYLVGENTTISVAVKGLAENSLDSLVFESLIPKPILQRYVSLLVEHRRIILSGPSGTGKTYLANRLSEYLVLREGRELTDGVVATFNVDHKSSKELRQYLSNLADQCASENNAMDMPLVIILDNLHHVSSLGEIFNGLLNCKDHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRMRNVELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSAAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSTSHQDDILDSSLESTL", "length": 2406, "header": "tr|A0ABI0P3W1-1|A0ABI0P3W1_BOVIN Computationally mapped isoform of Neuron navigator 2 OS=Bos taurus OX=9913 GN=NAV2 PE=3 SV=1 CANONICAL=A0ABI0NTX6-1" }, "locus": { "chromosome": "29", "start_pos": 25224098, "end_pos": 24804313, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138995.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138995.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107721.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107721.1" } ] } }, { "isoform_ac": "A0ABI0P6R1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6/entry#A0ABI0P6R1-1", "sequence": { "sequence": "MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTAYPSQIPLKSQGLQEPAGEGLPLRMSGSVENGFDTQIYTDWANHYLAKSGHKRLIKDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQQPPPPQKPHLPSPLPPPGSQVAGAPSQCQAGPPQQQVPATPQAPCQPHQPAPHQPSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSATANNRRSQSFNNYDKSKPVTSPPPPSSSHEKEPLASPASSHPAMSEDAPAALEGGGGCGPASCGASSAIPQPGSASKPWRSKSVSVKHSAAAAALSVKPPTPEPPRPAPEALKPAPNNQRSMLEKLKLFNSKGASKAGEGPGSRDTSCERLEILPSFEESEEMEAGGRPLSAAGPPSNSPKIALKGIAQRTFSRALTNKKSSPKGSEKEKEKQQREKEKSKDLTKRASVTERPDLREGPREDPSGAALTEMPKKSSKIASFIPKGGKLNSAKKEAPAPSHSGIPKPGMKSVPGKSPSAPTPSKDGERARGGKPSSGLPQQKPPLDGRHSSSSSSLASSEGKGPGGTGLNHSISSQTVSASVGTTQTTGSNTVSVQLPQPQQQYSHPNTATVAPFLYRSQTDTEGNVTAESSSGGVTMEPSHYTKSGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEISGRSILSLTGRPTPLAWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEAISMDAPGYMSDGDVLSKNMRADDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERSSLWSSEDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPAAPTGTLKTPGTGKTDDAKVSEKGRLSPKAAQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGATVTSRSATLGKIPKSSALVGRSTGRKTSMDGAQNQDDGYLSLSSRTNLQYRSLPRPSKSTSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAPQPVSSVAQATLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATLSQQGNLESPSGSGVLSSGSSSPLYSKNVDSTQSPLASSPSSAHSGPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGALSHNSSTGLIAASKDDALTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTTANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDTRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSIYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGSSQATDLRIRRQHSSDSVSSINSATSHSSVGSNIETDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSLSASPRQSLGLSQHSLNLAESSSLDMLLDDAGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHIDPVSQLGLNSDSVLGYSIGDVKRSNTSETPELLPCGYLVGENTTISVAVKGLAENSLDSLVFESLIPKPILQRYVSLLVEHRRIILSGPSGTGKTYLANRLSEYLVLREGRELTDGVVATFNVDHKSSKELRQYLSNLADQCASENNAMDMPLVIILDNLHHVSSLGEIFNGLLNCKDHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRMRNVELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSAAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSTSHQDDILDSSLESTL", "length": 2428, "header": "tr|A0ABI0P6R1-1|A0ABI0P6R1_BOVIN Computationally mapped isoform of Neuron navigator 2 OS=Bos taurus OX=9913 GN=NAV2 PE=3 SV=1 CANONICAL=A0ABI0NTX6-1" }, "locus": { "chromosome": "29", "start_pos": 25224098, "end_pos": 24804313, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143075.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143075.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107255.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107255.1" } ] } }, { "isoform_ac": "F1MHF3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6/entry#F1MHF3-1", "sequence": { "sequence": "MLWPRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERSSLWSSEDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPAAPTGTLKTPGTGKTDDAKVSEKGRLSPKAAQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGATVTSRSATLGKIPKSSALVGRSTGRKTSMDGAQNQDDGYLSLSSRTNLQYRSLPRPSKSTSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAPQPVSSVAQATLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATLSQQGNLESPSGSGVLSSGSSSPLYSKNVDSTQSPLASSPSSAHSGPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGALSHNSSTGLIAASKDDALTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTTANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDTRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSIYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGSSQATDLRIRRQHSSDSVSSINSATSHSSVGSNIETDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSLSASPRQSLGLSQHSLNLAESSSLDMLLDDAGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHIDPVSQLGLNSDSVLGYSIGDVKRSNTSETPELLPCGYLVGENTTISVAVKGLAENSLDSLVFESLIPKPILQRYVSLLVEHRRIILSGPSGTGKTYLANRLSEYLVLREGRELTDGVVATFNVDHKSSKELRQYLSNLADQCASENNAMDMPLVIILDNLHHVSSLGEIFNGLLNCKDHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRMRNVELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSAAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSTSHQDDILDSSLESTL", "length": 1493, "header": "tr|F1MHF3-1|A0ABI0NTX6_BOVIN Computationally mapped isoform of Neuron navigator 2 OS=Bos taurus OX=9913 GN=NAV2 PE=3 SV=4 CANONICAL=A0ABI0NTX6-1" }, "locus": { "chromosome": "29", "start_pos": 24891329, "end_pos": 24804313, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024536.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024536.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024536.7", "url": "https://www.ensembl.org/id/ENSBTAP00000024536.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 580, "start_aa": "Thr", "end_pos": 580, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr580", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100139508", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100139508", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTX6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTX6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTX6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1206, "end_pos": 1208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1216, "end_pos": 1218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1246, "end_pos": 1248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1258, "end_pos": 1260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1386, "end_pos": 1388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1426, "end_pos": 1428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1542, "end_pos": 1544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1585, "end_pos": 1587, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1673, "end_pos": 1675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1727, "end_pos": 1729, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1818, "end_pos": 1820, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2037, "end_pos": 2039, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2054, "end_pos": 2056, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2223, "end_pos": 2225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2306, "end_pos": 2308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2402, "end_pos": 2404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2414, "end_pos": 2416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 629, "end_pos": 631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" }, { "start_pos": 760, "end_pos": 762, "annotation": "n_glycosylation_sequon" }, { "start_pos": 808, "end_pos": 810, "annotation": "n_glycosylation_sequon" }, { "start_pos": 912, "end_pos": 914, "annotation": "n_glycosylation_sequon" }, { "start_pos": 939, "end_pos": 941, "annotation": "n_glycosylation_sequon" }, { "start_pos": 946, "end_pos": 948, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", "F1N2W9-1", "E1BB03-1", "E1BMP7-1", "A0JND9-1", "E1BAS6-1", "A0AAA9RXM7-1", "Q59HJ6-1", "Q2KJ94-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "A0AAF6Z0E4-1", "G3MZH7-1", "F1MKC7-1", "A0AAA9S7V9-1", "A0AAF6YME1-1", "F1MFR1-1", "Q3T084-1", "E1B7X9-1", "A0ABI0P204-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LG16", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] } ] }, { "uniprot_ac": "A0A3Q1LQC3", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": 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"evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1LXD0", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] } ] }, { "uniprot_ac": "A0A3Q1M0A4", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A3Q1M0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0A4" } ] } ] }, { "uniprot_ac": "A0A3Q1M155", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] } ] }, { "uniprot_ac": "A0A3Q1M493", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] } ] }, { "uniprot_ac": "A0A3Q1M7R9", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1M7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R9" } ] } ] }, { "uniprot_ac": "A0A3Q1MDD8", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A3Q1MDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDD8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDD8" } ] } ] }, { "uniprot_ac": "A0A3Q1MR04", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MR04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR04" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A3Q1MR04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR04" } ] } ] }, { "uniprot_ac": "A0A3Q1MR43", "gene_name": "DDX46", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", 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"ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1MU57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU57" } ] } ] }, { "uniprot_ac": "A0A3Q1NMG4", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] } ] }, { "uniprot_ac": "A0AAA9RRF7", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RRF7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RRF7" } ] } ] }, { "uniprot_ac": "A0AAA9RUK3", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RUK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUK3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0AAA9RUK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUK3" } ] } ] }, { "uniprot_ac": "A0AAA9RXI8", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] } ] }, { "uniprot_ac": "A0AAA9RXM7", "gene_name": "HLTF", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXM7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXM7" } ] } ] }, { "uniprot_ac": "A0AAA9S5G9", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S5G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5G9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0AAA9S5G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5G9" } ] } ] }, { "uniprot_ac": "A0AAA9S7V9", "gene_name": "RECQL4", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0AAA9S7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V9" } ] } ] }, { "uniprot_ac": "A0AAA9SPF3", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SPF3", "database": "UniProtKB", "url": 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} ] } ] }, { "uniprot_ac": "A0AAA9T674", "gene_name": "DDX56", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9T674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T674" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9T674", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T674" } ] } ] }, { "uniprot_ac": "A0AAA9T8W7", "gene_name": "PIF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0AAA9T8W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8W7" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0AAA9T8W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8W7" } ] } ] }, { "uniprot_ac": "A0AAA9TGZ3", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9TGZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGZ3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9TGZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGZ3" } ] } ] }, { "uniprot_ac": "A0AAA9TT27", "gene_name": "ATRX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9TT27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT27" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0AAA9TT27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT27" } ] } ] }, { "uniprot_ac": "A0AAA9TT64", "gene_name": "DNA2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9TT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT64" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0AAA9TT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT64" } ] } ] }, { "uniprot_ac": "A0AAA9U2H6", "gene_name": "IGHMBP2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9U2H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U2H6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9U2H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U2H6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9U2H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U2H6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0AAA9U2H6", "database": 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"RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0AAF6YME1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YME1" } ] } ] }, { "uniprot_ac": "A0AAF6YVB0", "gene_name": "MCM3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAF6YVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YVB0" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0AAF6YVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YVB0" } ] } ] }, { "uniprot_ac": "A0AAF6Z0E4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAF6Z0E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0E4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0AAF6Z0E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0E4" } ] } ] }, { "uniprot_ac": "A0AAF6Z0U5", "gene_name": "EIF4A2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAF6Z0U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0U5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAF6Z0U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0U5" } ] } ] }, { "uniprot_ac": "A0AAF6Z733", "gene_name": "DHX9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAF6Z733", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z733" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAF6Z733", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z733" } ] } ] }, { "uniprot_ac": "A0ABI0NSA6", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0NSA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0NSA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ] } ] }, { "uniprot_ac": "A0ABI0NX25", "gene_name": "RIGI", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0NX25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0NX25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ] } ] }, { "uniprot_ac": "A0ABI0NXS3", "gene_name": "DDX42", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0NXS3", "database": 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"evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] } ] }, { "uniprot_ac": "A0ABI0P467", "gene_name": "SKIC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] } ] }, { "uniprot_ac": "A0JND9", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": 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{ "id": "A4K436", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4K436" } ] } ] }, { "uniprot_ac": "A5D7C1", "gene_name": "DDX52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] } ] }, { "uniprot_ac": "A5PJA1", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] } ] }, { "uniprot_ac": "A5PJI5", "gene_name": "GET3", "activity": [ { "ec_number": "3.6.4.-", 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} ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BAN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAN8" } ] } ] }, { "uniprot_ac": "E1BAS6", "gene_name": "SETX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] } ] }, { "uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", 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"ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] } ] }, { "uniprot_ac": "Q0IIK5", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0IIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIK5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q0IIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIK5" } ] } ] }, { "uniprot_ac": "Q0V8B7", "gene_name": "MCM5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0V8B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8B7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q0V8B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8B7" } ] } ] }, { 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{ "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q28141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28141" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q28141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28141" } ] } ] }, { "uniprot_ac": "Q29S22", "gene_name": "DDX47", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q29S22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29S22" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q29S22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29S22" } ] } ] }, { "uniprot_ac": "Q2HJF8", "gene_name": "RHOT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q2HJF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF8" } ] } ] }, { "uniprot_ac": "Q2KIZ8", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] } ] }, { "uniprot_ac": "Q2KJ94", "gene_name": "RAD51", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q2KJ94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ94" } ] } ] }, { "uniprot_ac": "Q2KJI7", "gene_name": "AFG3L2", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKZ1" } ] } ] }, { "uniprot_ac": "Q2NL08", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL08" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2NL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL08" } ] } ] }, { "uniprot_ac": "Q2NL22", "gene_name": "EIF4A3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NL22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL22" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2NL22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL22" } ] } ] }, { "uniprot_ac": "Q2T9X2", "gene_name": "CCT4", "activity": [ { "ec_number": 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"MSQTSLKQKKKNETGSRYSKDSLEGDKSRKDSEKSVRLTTQMRRAVIPNHSLRCCSMRGHPSCRRCLCAAEGKVLLSPCRTIRIYIHMCLLWEQGRQITMIRGSQELTLPKSDSRGYVVRNQWSRTSRSPSTRPPSAEESRSKNTSLKLPSSSTTSRTSSTSPSHQESPKQLSAQPSPTTQNMPLDSRNSMSPEAQLQTTSRRTTKSENPDTWSHSTGREMREGREKRESRDTRDMSRSRDSHDSRDTHQREYSRTPPSEWKSYTQRRMLYPSQMDHDCVSELARKREEEEDEDEAYWASVRTLYEKTPNCSRPRPPKPKHAITVAVSSGALFNMMDSRKIYDEEGLEKYMEYQLTNENVVLTPGPAFRFVKALQHVNCRLRELYPDEQDLFDIVLMTNNHAQVGVRLINSVNHYGLLIDRFCLTGGKSPIGYLKAYLTNLYVSADSDKVLEAIQEGIASATMYEGAKDMSYCDTQLRVVFDGDAVLFCEEPEHSTKDHGLDKCFQHEALADNKPLGQGPLKGFMEDLGRLQKKFYAKDERLCCPIRTYLVTARSAASSGARVLKTLRRWGLEIDEALFLAGAPKGPILAKIRPHLFFDDHMFHIEGAQKYGTTTAHVPYGISQK", "length": 625, "header": "tr|A0ABI0NPF8-1|A0ABI0NPF8_BOVIN Isoform 1 of 5'-nucleotidase, cytosolic IB OS=Bos taurus OX=9913 GN=NT5C1B PE=4 SV=1 CANONICAL=A0ABI0NPF8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NPF8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPF8/entry#A0ABI0NPF8-1", "sequence": { "sequence": "MSQTSLKQKKKNETGSRYSKDSLEGDKSRKDSEKSVRLTTQMRRAVIPNHSLRCCSMRGHPSCRRCLCAAEGKVLLSPCRTIRIYIHMCLLWEQGRQITMIRGSQELTLPKSDSRGYVVRNQWSRTSRSPSTRPPSAEESRSKNTSLKLPSSSTTSRTSSTSPSHQESPKQLSAQPSPTTQNMPLDSRNSMSPEAQLQTTSRRTTKSENPDTWSHSTGREMREGREKRESRDTRDMSRSRDSHDSRDTHQREYSRTPPSEWKSYTQRRMLYPSQMDHDCVSELARKREEEEDEDEAYWASVRTLYEKTPNCSRPRPPKPKHAITVAVSSGALFNMMDSRKIYDEEGLEKYMEYQLTNENVVLTPGPAFRFVKALQHVNCRLRELYPDEQDLFDIVLMTNNHAQVGVRLINSVNHYGLLIDRFCLTGGKSPIGYLKAYLTNLYVSADSDKVLEAIQEGIASATMYEGAKDMSYCDTQLRVVFDGDAVLFCEEPEHSTKDHGLDKCFQHEALADNKPLGQGPLKGFMEDLGRLQKKFYAKDERLCCPIRTYLVTARSAASSGARVLKTLRRWGLEIDEALFLAGAPKGPILAKIRPHLFFDDHMFHIEGAQKYGTTTAHVPYGISQK", "length": 625, "header": "tr|A0ABI0NPF8-1|A0ABI0NPF8_BOVIN Isoform 1 of 5'-nucleotidase, cytosolic IB OS=Bos taurus OX=9913 GN=NT5C1B PE=4 SV=1 CANONICAL=A0ABI0NPF8-1" }, "locus": { "chromosome": "11", "start_pos": 80157689, "end_pos": 80143790, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154473.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154473.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104922.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104922.1" } ] } }, { "isoform_ac": "F1ML59-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPF8/entry#F1ML59-1", "sequence": { "sequence": "MSQTSLKQKKKNETGSRYSKDSLEGDKSRKDSEKSVRLTTQGSQELTLPKSDSRGYVVRNQWSRTSRSPSTRPPSAEESRSKNTSLKLPSSSTTSRTSSTSPSHQESPKQLSAQPSPTTQNMPLDSRNSMSPEAQLQTTSRRTTKSENPDTWSHSTGREMREGREKRESRDTRDMSRSRDSHDSRDTHQREYSRTPPSEWKSYTQRRMLYPSQMDHDCVSELARKREEEEDEDEAYWASVRTLYEKTPNCSRPRPPKPKHAITVAVSSGALFNMMDSRKIYDEEGLEKYMEYQLTNENVVLTPGPAFRFVKALQHVNCRLRELYPDEQDLFDIVLMTNNHAQVGVRLINSVNHYGLLIDRFCLTGGKSPIGYLKAYLTNLYVSADSDKVLEAIQEGIASATMYEGAKDMSYCDTQLRVVFDGDAVLFCEEPEHSTKDHGLDKCFQHEALADNKPLGQGPLKGFMEDLGRLQKKFYAKDERLCCPIRTYLVTARSAASSGARVLKTLRRWGLEIDEALFLAGAPKGPILAKIRPHLFFDDHMFHIEGAQKYGTTTAHVPYGISQK", "length": 564, "header": "tr|F1ML59-1|A0ABI0NPF8_BOVIN Computationally mapped isoform of 5'-nucleotidase, cytosolic IB OS=Bos taurus OX=9913 GN=NT5C1B PE=4 SV=1 CANONICAL=A0ABI0NPF8-1" }, "locus": { "chromosome": "11", "start_pos": 80157689, "end_pos": 80143790, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006950.5", "url": "https://www.ensembl.org/id/ENSBTAT00000006950.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006950.3", "url": "https://www.ensembl.org/id/ENSBTAP00000006950.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-74259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-74259", "resource": "Reactome", "description": "Purine catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JX78-1", "protein_name": "5'-nucleotidase, cytosolic IB", "gene_name": "Nt5c1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQTSLKTKKKNEPGMRYSKESLDAEKRKDSDKSGARLSTQMRRVGYPNHSLRCCPMRYHHFCRRCLCAAEGTSPCRTIRIYIHMCLFWEQGRQITMIRGSQEIPVPNTDSRGYVVRNQWSRTSRSPSTRAPSVDENRSRNTVVKQAPNSSANSRTSSASASQHETSTSPPPQVSEKSPVQQPSPQTRTITPLDSQPPTPPETEPDSRRTSKMYTATDPWAHRDNREPRDLQLREYAHSCDSREGIPKTREYPRTPPTEWKSYVQRRLQYGSSVDMDPDCLPDGQHHRQKQQIEEDEVDEAYWSSVSMLYEKIPSCTRPRPPKPKHAITIAVSSRALFNMVDDRKIYEEEGLEKYMEYQLTNENVILTPGPAFRFVKALQHVNSRLRDLYPDEQDLFDIVLMTNNHAQVGVRLINSVNHYGLLIDRFCLTGGKSPIGYLKAYLTNLYLSADSEKVQEAIKEGIASATMFAGAKDMAYCDTQLRVAFDGDAVLFSDESEHIAKDHGLDKFFQHETLFENKPLAQGPLKGFLEDLGKLQKKFYAKDERLLCPIRTYLVTARSAASSGARVLKTLRRWGLEIDEALFLAGAPKGPILVKIRPHIFFDDQMFHIEAAQKFGTITAHVPYGIAQKRN", "length": 632 }, "evidence": [ { "id": "A0ABI0NPF8", "url": "https://omabrowser.org/oma/group/A0ABI0NPF8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91YE9-1", "protein_name": "Cytosolic 5'-nucleotidase 1B", "gene_name": "Nt5c1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQTSLKHKKKNEPGMRYSKESLDAEKRKDSDKTGARLSTQGSQELPLHNTDSRGYVVRNQWSRTSRSPSTGAPSVDEPRSRNTAIKVEAPNSSTTSRTSSASPSQHETSPPPQTSEKSSIQQTPQNRPITQLESQPPTPPETEPNSRRTSAKMYTGSDPWAHRENREPRDLQLRDYAYSCDSREGMPKTREYPRTPPTEWKPYAQRRLQYGTSVDMEPEYISDGPQQRQRQQTEEDEVDEAYWTSVSMLYEKIPSCARPRPPKPKHAITIAVSSRALFNMVDDRKIYEEEGLEKYMEYQLTNENVILTPGPAFRFVKALQHVNSRLRDLYPDEQDLFDIVLMTNNHAQVGVRLINSVNHYGLLIDRFCLTGGKSPIGYLKAYLTNLYLSADSEKVQEAIKEGIASATMYAGAKDMAYCDTQLRVAFDGDAVLFSDESEHIAKDHGLDKFFQHETLFENKPLAQGPLKSFLEDLGKLQKKFYAKDERLLCPIRTYLVTARSAASSGARVLKTLRRWGLEIDEALFLAGAPKGPILVKIRPHIFFDDQMFHIESAQKFGTITAHVPYGIAQKRN", "length": 573 }, "evidence": [ { "id": "A0ABI0NPF8", "url": "https://omabrowser.org/oma/group/A0ABI0NPF8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96P26-1", "protein_name": "Cytosolic 5'-nucleotidase 1B", "gene_name": "NT5C1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQTSLKQKKNEPGMRSSKESLEAEKRKESDKTGVRLSNQMRRAVNPNHSLRCCPFQGHSSCRRCLCAAEGTALGPCHTIRIYIHMCLLWEQGQQITMMRGSQESSLRKTDSRGYLVRSQWSRISRSPSTKAPSIDEPRSRNTSAKLPSSSTSSRTPSTSPSLHDSSPPPLSGQPSLQPPASPQLPRSLDSRPPTPPEPDPGSRRSTKMQENPEAWAQGIVREIRQTRDSQPLEYSRTSPTEWKSSSQRRGIYPASTQLDRNSLSEQQQQQREDEDDYEAAYWASMRSFYEKNPSCSRPWPPKPKNAITIALSSCALFNMVDGRKIYEQEGLEKYMEYQLTNENVILTPGPAFRFVKALQYVNARLRDLYPDEQDLFDIVLMTNNHAQVGVRLINSVNHYGLLIDRFCLTGGKDPIGYLKAYLTNLYIAADSEKVQEAIQEGIASATMFDGAKDMAYCDTQLRVAFDGDAVLFSDESEHFTKEHGLDKFFQYDTLCESKPLAQGPLKGFLEDLGRLQKKFYAKNERLLCPIRTYLVTARSAASSGARVLKTLRRWGLEIDEALFLAGAPKSPILVKIRPHIFFDDHMFHIEGAQRLGSIAAYGFNKKFSS", "length": 610 }, "evidence": [ { "id": "A0ABI0NPF8", "url": "https://omabrowser.org/oma/group/A0ABI0NPF8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPF8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPF8" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPF8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPF8" } ], "pmid": "" }, { "name": "5'-nucleotidase activity", "id": "GO:0008253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008253", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPF8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPF8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPF8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPF8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPF8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPF8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nucleotide metabolic process", "id": "GO:0009117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009117", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPF8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPF8" } ], "pmid": "" }, { "name": "adenosine metabolic process", "id": "GO:0046085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046085", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPF8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 }, { "start_pos": 144, "end_pos": 146 }, { "start_pos": 310, "end_pos": 312 }, { "start_pos": 49, "end_pos": 51 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NMY1-1", "uniprot_ac": "A0ABI0NMY1", "uniprot_id": "A0ABI0NMY1_BOVIN", "mass": { "chemical_mass": 78330.0, "monoisotopic_mass": 78330.0 }, "refseq": {}, "gene_names": [ { "name": "MPHOSPH10", "type": "recommended", "evidence": [ { "id": "A0ABI0NMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMY1" } ] } ], "protein_names": [ { "name": "U3 small nucleolar ribonucleoprotein protein MPP10", "type": "recommended", "evidence": [ { "id": "A0ABI0NMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMY1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.", "evidence": [ { "database": "UniProtKB", "id": "F1MQV1", "url": "https://www.uniprot.org/uniprotkb/F1MQV1#function" }, { "database": "UniProtKB", "id": "PIRNR017300", "url": "https://www.uniprot.org/uniprotkb/PIRNR017300#function" }, { "database": "UniProtKB", "id": "A0ABI0NMY1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMY1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMY1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMY1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MPHOSPH10", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMY1", "locus": { "chromosome": "21", "start_pos": 27409258, "end_pos": 27396948, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009854", "url": "https://www.ensembl.org/id/ENSBTAG00000009854" } ] } } ], "crossref": [ { "id": "ENSBTAG00000009854", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009854", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR012173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MQV1", "url": "https://www.orthodb.org/?gene=F1MQV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17039", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17039", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17039:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17039:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04006", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04006", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NMY1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMY1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MQV1", "url": "https://www.uniprot.org/uniprotkb/F1MQV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MQV1-1", "url": "https://www.uniprot.org/uniprotkb/F1MQV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARPAWRRRTLERCLREVGKATDSPECFLTIQDELASKFTSLTKVLYDFNKVLENDRKHGSPLKKLMINNFDDEQIWQQLELQNEPILQHFQSAVSETIEDEDISLLPESEEQECEEDVMELEAAGQEDLEQDLEEEEVSDLSADDPEADERAKNSSKLDLRKSPDFSDEDSDLDFDISKLERQSKVQSRVPRKPTEKSIVDDKFFKLSEMETFLENMEKEEEQRDDQEEDDIDFFEDVDSDEDEGGLFGGQDLKSGKSSRNLKYKDFFDPVESDEDVASVQDDGNELASNEEEEIAEGEESISETDEDDDLEESGDSKQHKETLKRVTFALPNDEDTEDTNILNVQKDSDEVKSSFEKRQEKMNEKIASLEKELLEKKPWQLQGEVTAQKRPENSLLEETLHFDHAVRMAPVITEETTLQLEDIIKQRIKDQAWDDVVRKEKPKEDAFEYKKRLTLDHEKSKLSLAEIYEQEYIKLNQQKTAEEENPEHVEIQKMMDSLFLKLDALSNFHFIPKPPVPEIKVVSNLPAVTMEEVAPVSVSDAALLAPEEVKEKNKAGDIKTAAEKTATDKKRERRKKKYQKHLKIKEKEKRRRLLEKNNPDQAGRYTKAVASEKLKQLTKTGKASLLKDEGKDKALKSSQAFFSKLQDQVKMQISNAKKTEKKKKKNQDISVHKLKL", "length": 678, "header": "tr|A0ABI0NMY1-1|A0ABI0NMY1_BOVIN Isoform 1 of U3 small nucleolar ribonucleoprotein protein MPP10 OS=Bos taurus OX=9913 GN=MPHOSPH10 PE=3 SV=1 CANONICAL=A0ABI0NMY1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NMY1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMY1/entry#A0ABI0NMY1-1", "sequence": { "sequence": "MARPAWRRRTLERCLREVGKATDSPECFLTIQDELASKFTSLTKVLYDFNKVLENDRKHGSPLKKLMINNFDDEQIWQQLELQNEPILQHFQSAVSETIEDEDISLLPESEEQECEEDVMELEAAGQEDLEQDLEEEEVSDLSADDPEADERAKNSSKLDLRKSPDFSDEDSDLDFDISKLERQSKVQSRVPRKPTEKSIVDDKFFKLSEMETFLENMEKEEEQRDDQEEDDIDFFEDVDSDEDEGGLFGGQDLKSGKSSRNLKYKDFFDPVESDEDVASVQDDGNELASNEEEEIAEGEESISETDEDDDLEESGDSKQHKETLKRVTFALPNDEDTEDTNILNVQKDSDEVKSSFEKRQEKMNEKIASLEKELLEKKPWQLQGEVTAQKRPENSLLEETLHFDHAVRMAPVITEETTLQLEDIIKQRIKDQAWDDVVRKEKPKEDAFEYKKRLTLDHEKSKLSLAEIYEQEYIKLNQQKTAEEENPEHVEIQKMMDSLFLKLDALSNFHFIPKPPVPEIKVVSNLPAVTMEEVAPVSVSDAALLAPEEVKEKNKAGDIKTAAEKTATDKKRERRKKKYQKHLKIKEKEKRRRLLEKNNPDQAGRYTKAVASEKLKQLTKTGKASLLKDEGKDKALKSSQAFFSKLQDQVKMQISNAKKTEKKKKKNQDISVHKLKL", "length": 678, "header": "tr|A0ABI0NMY1-1|A0ABI0NMY1_BOVIN Isoform 1 of U3 small nucleolar ribonucleoprotein protein MPP10 OS=Bos taurus OX=9913 GN=MPHOSPH10 PE=3 SV=1 CANONICAL=A0ABI0NMY1-1" }, "locus": { "chromosome": "21", "start_pos": 27409160, "end_pos": 27396980, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147153.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147153.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106911.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106911.1" } ] } }, { "isoform_ac": "F1MQV1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMY1/entry#F1MQV1-1", "sequence": { "sequence": "MARPAWRRRTLERCLREVGKATDSPECFLTIQDELASKFTSLTKVLYDFNKVLENDRKHGSPLKKLMINNFDDEQIWQQLELQNEPILQHFQSAVSETIEDEDISLLPESEEQECEEDVMELEAAGQEDLEQDLEEEEVEEAEEVEVSDLSADDPEADERAKNSSKLDLRKSPDFSDEDSDLDFDISKLERQSKVQSRVPRKPTEKSIVDDKFFKLSEMETFLENMEKEEEQRDDQEEDDIDFFEDVDSDEDEGGLFGGQDLKSGKSSRNLKYKDFFDPVESDEDVASVQDDGNELASNEEEEIAEGEESISETDEDDDLEESGDSKQHKETLKRVTFALPNDEDTEDTNILNVQKDSDEVKSSFEKRQEKMNEKIASLEKELLEKKPWQLQGEVTAQKRPENSLLEETLHFDHAVRMVHVLYPLAPVITEETTLQLEDIIKQRIKDQAWDDVVRKEKPKEDAFEYKKRLTLDHEKSKLSLAEIYEQEYIKLNQQKTAEEENPEHVEIQKMMDSLFLKLDALSNFHFIPKPPVPEIKVVSNLPAVTMEEVAPVSVSDAALLAPEEVKEKNKAGDIKTAAEKTATDKKRERRKKKYQKHLKIKEKEKRRRLLEKNNPDQAGRYTKAVASEKLKQLTKTGKASLLKDEGKDKALKSSQAFFSKLQDQVKMQISNAKKTEKKKKKNQDISVHKLKL", "length": 693, "header": "tr|F1MQV1-1|A0ABI0NMY1_BOVIN Computationally mapped isoform of U3 small nucleolar ribonucleoprotein protein MPP10 OS=Bos taurus OX=9913 GN=MPHOSPH10 PE=3 SV=2 CANONICAL=A0ABI0NMY1-1" }, "locus": { "chromosome": "21", "start_pos": 27409160, "end_pos": 27396980, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012993.6", "url": "https://www.ensembl.org/id/ENSBTAT00000012993.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012993.4", "url": "https://www.ensembl.org/id/ENSBTAP00000012993.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMY1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMY1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "sno(s)RNA-containing ribonucleoprotein complex", "id": "GO:0005732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005732", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMY1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMY1" } ], "pmid": "" }, { "name": "Mpp10 complex", "id": "GO:0034457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034457", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMY1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMY1" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMY1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NT64-1", "uniprot_ac": "A0ABI0NT64", "uniprot_id": "A0ABI0NT64_BOVIN", "mass": { "chemical_mass": 275578.0, "monoisotopic_mass": 275578.0 }, "refseq": {}, "gene_names": [ { "name": "FASN", "type": "recommended", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] } ], "protein_names": [ { "name": "Fatty acid synthase", "type": "recommended", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.100", "type": "synonym", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64/entry#names_and_taxonomy" } ] }, { "name": "1.3.1.39", "type": "synonym", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.38", "type": "synonym", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.39", "type": "synonym", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.41", "type": "synonym", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.85", "type": "synonym", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64/entry#names_and_taxonomy" } ] }, { "name": "3.1.2.14", "type": "synonym", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64/entry#names_and_taxonomy" } ] }, { "name": "4.2.1.59", "type": "synonym", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LVA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVA9#function" }, { "database": "UniProtKB", "id": "ARBA00023442", "url": "https://www.uniprot.org/uniprotkb/ARBA00023442#function" }, { "database": "UniProtKB", "id": "A0A3Q1MPB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPB3#function" }, { "database": "UniProtKB", "id": "F1N647", "url": "https://www.uniprot.org/uniprotkb/F1N647#function" }, { "database": "UniProtKB", "id": "A0ABI0NT64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FASN", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64", "locus": { "chromosome": "19", "start_pos": 50794939, "end_pos": 50776247, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015980", "url": "https://www.ensembl.org/id/ENSBTAG00000015980" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015980", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015980", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00833", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00833", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05195", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05195", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08954", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08954", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020807", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020807", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049391", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049391", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049552", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049552", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KMRGGEF", "url": "https://omabrowser.org/oma/group/KMRGGEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N647", "url": "https://www.orthodb.org/?gene=F1N647", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43775", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43775", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43775:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43775:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00109", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00109", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00550", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00550", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00975", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00975", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02801", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02801", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08242", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08242", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08659", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08659", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16197", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16197", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21149", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21149", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-199220", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-199220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-75105", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "13097", "url": "https://www.rhea-db.org/rhea/13097", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "17397", "url": "https://www.rhea-db.org/rhea/17397", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "22564", "url": "https://www.rhea-db.org/rhea/22564", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "22836", "url": "https://www.rhea-db.org/rhea/22836", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "30123", "url": "https://www.rhea-db.org/rhea/30123", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41788", "url": "https://www.rhea-db.org/rhea/41788", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41792", "url": "https://www.rhea-db.org/rhea/41792", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41800", "url": "https://www.rhea-db.org/rhea/41800", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41804", "url": "https://www.rhea-db.org/rhea/41804", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41808", "url": "https://www.rhea-db.org/rhea/41808", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41812", "url": "https://www.rhea-db.org/rhea/41812", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41820", "url": "https://www.rhea-db.org/rhea/41820", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41824", "url": "https://www.rhea-db.org/rhea/41824", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41828", "url": "https://www.rhea-db.org/rhea/41828", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41832", "url": "https://www.rhea-db.org/rhea/41832", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41836", "url": "https://www.rhea-db.org/rhea/41836", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41840", "url": "https://www.rhea-db.org/rhea/41840", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41844", "url": "https://www.rhea-db.org/rhea/41844", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41848", "url": "https://www.rhea-db.org/rhea/41848", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41852", "url": "https://www.rhea-db.org/rhea/41852", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41856", "url": "https://www.rhea-db.org/rhea/41856", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41860", "url": "https://www.rhea-db.org/rhea/41860", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41864", "url": "https://www.rhea-db.org/rhea/41864", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41868", "url": "https://www.rhea-db.org/rhea/41868", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41872", "url": "https://www.rhea-db.org/rhea/41872", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41876", "url": "https://www.rhea-db.org/rhea/41876", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41880", "url": "https://www.rhea-db.org/rhea/41880", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41884", "url": "https://www.rhea-db.org/rhea/41884", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41888", "url": "https://www.rhea-db.org/rhea/41888", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41892", "url": "https://www.rhea-db.org/rhea/41892", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41896", "url": "https://www.rhea-db.org/rhea/41896", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41900", "url": "https://www.rhea-db.org/rhea/41900", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41904", "url": "https://www.rhea-db.org/rhea/41904", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41908", "url": "https://www.rhea-db.org/rhea/41908", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41912", "url": "https://www.rhea-db.org/rhea/41912", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41916", "url": "https://www.rhea-db.org/rhea/41916", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41920", "url": "https://www.rhea-db.org/rhea/41920", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41924", "url": "https://www.rhea-db.org/rhea/41924", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41928", "url": "https://www.rhea-db.org/rhea/41928", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41932", "url": "https://www.rhea-db.org/rhea/41932", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LVA9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT64-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N647", "url": "https://www.uniprot.org/uniprotkb/F1N647", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N647-1", "url": "https://www.uniprot.org/uniprotkb/F1N647-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKPSEAERAAMEEVVITGMSGKLPESENLEEFWANLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRFDASFFGVHPKQAHNMDPQLRLLLEVTYEAIVDAGINPASIRGTNTGVWVGVSGSEASEALSRDPETLVGYSMVGCQRAMLANRLSFFFDFKGPSITLDTACSSSLLALQRAYQAIQRGECAMAIVGGVNILLKPNTSVQFMKLGMLSPEGTCKSFDASGNGYCRAEAVMAILLTKKSLARRVYATILNAGTNTDGCKEKGVTFPSGEAQEQLISSLYKPAGLDPETLEYVEAHGTGTKVGDPQELNGIVQALCGTRQSPLRIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHNPNPKIPALQDGRLQVVDRPLPVLGGNVGINSFGFGGSNVHVILQPNSQPLPPPAPHAALPRLLRASGRTLEGVQGLLELGLQHSQNLAFVSMLNDIAAPSPAAMPFRGYAVLGSQGGSQEVQQVLAGKRPLWFICSGMGTQWRGMGLSLMRLSRFRDSILRSDEAVKPLGLQVSQLLLSTDEAIFDDMVISFVSLTAIQIALIDLLTSMGLQPDGIIGHSLGEVACGYADGCISQEEAILSAYWRGQCIKEANIPPGAMAAVGLTWEECKQRCPPGIVPACHNCIDTVTISGPQASMLEFVQQLKQEGVFAKEVRTGGMAFHSYFMDAIAPMLLQQLKKVIREPQPRSPRWLSTSIPETQWQESLARTFSAEYNVNNLVSPVLFQEALWRVPEDAVVLEIAPHALLQAVLKRGLKSSCTIIPLMKKDHRDNLEFFLSNVGQLYLTGIDVNPNGLFPPVEFPAPRGTPLISPHIKWDHSQTWDVPTAEDFPSGSSSSSATIYKIDINPESPDHYLVDHCIDGRIIFPGTGYLCLVWKTLARALDQNMEHTPVVFEDVTLHQAVILPKTGIVLLEVRLLEASCTFEVSENGNLIASGKVYQWEDPNPKLFDNRYGPDPATPVDPTTAIHLCRGDVYKELQLQGFNYGPYFQGILEASSEGNTGQLLWKDNWVTFMDTMLQMSILAPSKRSLRLPTRITAIYIHPATHQQKLYTLQDKTQVADVVINRCLDTTVAGGIYISRIHTSVAPRHQQEQLVPILEKFCFTPHVETGCLAGNLALQEELQLCVGLAQALQTRVAQQGIKMVVPGLDGAQAPQEAPQQGLPRLLATACQLQLNGNLQMEMGQILAQERALLCDDPLLSGLLNSPALKACVDTALENMTSLKMKVVEVLAGDGQLYSRIPTLLNTQPLLELDYTATDRHPQALEAAQAKLQQLDITQGQWDPSDPAPSNLGGANLVVCNYALASLGDPATAVGNMVAALKEGGFLLLHTLLRGHPLGETVTFLTCPEPQQGQRHLLSQDEWERLFAGASLYLVALKKSFYGSVLFLCRRLAPLDSPIFLPVEDTSFQWVDSLKNILADSSSRPVWLMAVGCTTSGVVGLVNCLRKEPDGHRIRCVLVSNLNSTSPIPETDPKSLELQKVLQSDLVMNVYRDGAWGAFRHFPLEQDKPEEQTEHAFINVLTRGDLSSIRWVCSPLRHSQPTAPGFQLCTIYYASLNFRDIMLATGKLSPDAIPGNWASRNCLLGMEFSGRDASGKRVMGLVPAEGLATSTLVPQSFLWDVPSNWTLEEAASVPVVYSTAYYALMVRGRMQPGETVLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQSRFPQLNETSFANSRDTSFEQHVLWHTAGKGADLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSKNHPLGMAIFLKNVTFHGILLDSLFEENNTMWQEVSTLLKAGIREGVVQPLKRTVFPRTQAEDAFRYMAQGKHIGKVVLQVREEEQEAVLHGTKPTQMVALCKTFCPAHKSYIITGGLGGFGLELAHWLVERGAQKLVLTSRSGIRTGYQARQVHEWRRQGVQVLVSTSDVSALDGTRSLITEAAQLGPVGGIFNLAVVLRDAMLDNQTPEFFQDVNKPKYNGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQTNYGFANSTMERICEKRRHDGLPGLAVQWGAIADVGLLMELKGTKDKAIGGTLPQRITSCMEVLDLFLNQPHPVLSSFVLAEKATSRGPSGSHQDLVKAVTHILGIRDLATVNLDSSLSDLGLDSLMGVEVRQMLEREHNLLLSMREIRQLTIHKLQEISAQAGTADELTDSTPKFGSPAQSQTQLNLSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSTTVFHSLATKLSIPTYGLQCTGAAPLDSIQSLATYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAQQNAGPTNNSLFLFDGSHTFVMAYTQSYRAKLNPGCEAEAEAEAMCFFMQQFTEAEHSRVLEALLPLGDLEARVAATVELIVQSHAGLDRHALSFAARSFYHKLRAAEEYTPRATYHGNVTLLRAKMGSAYQEGLGADYNLSQVCDGKVSVHIIEGDHRTLLEGSGLESILSIIHSSLAEPRVSVREG", "length": 2526, "header": "tr|A0ABI0NT64-1|A0ABI0NT64_BOVIN Isoform 1 of Fatty acid synthase OS=Bos taurus OX=9913 GN=FASN PE=1 SV=1 CANONICAL=A0ABI0NT64-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVA9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64/entry#A0A3Q1LVA9-1", "sequence": { "sequence": "MEEVVITGMSGKLPESENLEEFWANLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRFDASFFGVHPKQAHNMDPQLRLLLEVTYEAIVDAGINPASIRGTNTGVWVGVSGSEASEALSRDPETLVGYSMVGCQRAMLANRLSFFFDFKGPSITLDTACSSSLLALQRAYQAIQRGECAMAIVGGVNILLKPNTSVQFMKLGMLSPEGTCKSFDASGNGYCRAEAVMAILLTKKSLARRVYATILNAGTNTDGCKEKGVTFPSGEAQEQLISSLYKPAGLDPETLEYVEAHGTGTKVGDPQELNGIVQALCGTRQSPLRIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHNPNPKIPALQDGRLQVVDRPLPVLGGNVGINSFGFGGSNVHVILQPNSQPLPPPAPHAALPRLLRASGRTLEGVQGLLELGLQHSQNLAFVSMLNDIAAPSPAAMPFRGYAVLGSQGGSQEVQQVLAGKRPLWFICSGMGTQWRGMGLSLMRLSRFRDSILRSDEAVKPLGLQVSQLLLSTDEAIFDDMVISFVSLTAIQIALIDLLTSMGLQPDGIIGHSLGEVACGYADGCISQEEAILSAYWRGQCIKEANIPPGAMAAVGLTWEECKQRCPPGIVPACHNCIDTVTISGPQASMLEFVQQLKQEGVFAKEVRTGGMAFHSYFMDAIAPMLLQQLKKVIREPQPRSPRWLSTSIPETQWQESLARTFSAEYNVNNLVSPVLFQEALWRVPEDAVVLEIAPHALLQAVLKRGLKSSCTIIPLMKKDHRDNLEFFLSNVGQLYLTGIDVNPNGLFPPVEFPAPRGTPLISPHIKWDHSQTWDVPTAEDFPSGSSSSSATIYKIDINPESPDHYLVDHCIDGRIIFPGTGYLCLVWKTLARALDQNMEHTPVVFEDVTLHQAVILPKTGIVLLEVRLLEASCTFEVSENGNLIASGKVYQWEDPNPKLFDNRYGPDPATPVDPTTAIHLCRGDVYKELQLQGFNYGPYFQGILEASSEGNTGQLLWKDNWVTFMDTMLQMSILAPSKRSLRLPTRITAIYIHPATHQQKLYTLQDKTQVADVVINRCLDTTVAGGIYISRIHTSVAPRHQQEQLVPILEKFCFTPHVETGCLAGNLALQEELQLCVGLAQALQTRVAQQGIKMVVPGLDGAQAPQEAPQQGLPRLLATACQLQLNGNLQMEMGQILAQERALLCDDPLLSGLLNSPALKACVDTALENMTSLKMKVVEVLAGDGQLYSRIPTLLNTQPLLELDYTATDRHPQALEAAQAKLQQLDITQGQWDPSDPAPSNLGGANLVVCNYALASLGDPATAVGNMVAALKEGGFLLLHTLLRGHPLGETVTFLTCPEPQQGQRHLLSQDEWERLFAGASLYLVALKKSFYGSVLFLCRRLAPLDSPIFLPVEDTSFQWVDSLKNILADSSSRPVWLMAVGCTTSGVVGLVNCLRKEPDGHRIRCVLVSNLNSTSPIPETDPKSLELQKVLQSDLVMNVYRDGAWGAFRHFPLEQDKPEEQTEHAFINVLTRGDLSSIRWVCSPLRHSQPTAPGFQLCTIYYASLNFRDIMLATGKLSPDAIPGNWASRNCLLGMEFSGRDASGKRVMGLVPAEGLATSTLVPQSFLWDVPSNWTLEEAASVPVVYSTAYYALMVRGRMQPGETVLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQSRFPQLNETSFANSRDTSFEQHVLWHTAGKGMAIFLKNVTFHGILLDSLFEENNTMWQEVSTLLKAGIREGVVQPLKRTVFPRTQAEDAFRYMAQGKHIGKVVLQVREEEQEAVLHGTKPTQMVALCKTFCPAHKSYIITGGLGGFGLELAHWLVERGAQKLVLTSRSGIRTGYQARQVHEWRRQGVQVLVSTSDVSALDGTRSLITEAAQLGPVGGIFNLAVVLRDAMLDNQTPEFFQDVNKPKYNGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQTNYGFANSTMERICEKRRHDGLPGLAVQWGAIADVGLLMELKGTKDKAIGGTLPQRITSCMEVLDLFLNQPHPVLSSFVLAEKATSRGPSGSHQDLVKAVTHILGIRDLATVNLDSSLSDLGLDSLMGVEVRQMLEREHNLLLSMREIRQLTIHKLQEISAQAGTADELTDSTPKFGSPAQSQTQLNLSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSTTVFHSLATKLSIPTYGLQCTGAAPLDSIQSLATYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAQQNAGPTNNSLFLFDGSHTFVMAYTQSYRAKLNPGCEAEAEAEAMCFFMQQFTEAEHSRVLEALLPLGDLEARVAATVELIVQSHAGLDRHALSFAARSFYHKLRAAEEYTPRATYHGNVTLLRAKMGSAYQEGLGADYNLSQVCDGKVSVHIIEGDHRTLLEGSGLESILSIIHSSLAEPRVSVREG", "length": 2474, "header": "tr|A0A3Q1LVA9-1|A0ABI0NT64_BOVIN Computationally mapped isoform of Fatty acid synthase OS=Bos taurus OX=9913 GN=FASN PE=1 SV=1 CANONICAL=A0ABI0NT64-1" }, "locus": { "chromosome": "19", "start_pos": 50794360, "end_pos": 50778202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076819.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076819.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061132.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061132.1" } ] } }, { "isoform_ac": "A0A3Q1MPB3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64/entry#A0A3Q1MPB3-1", "sequence": { "sequence": "MPKPSEAERAAMEEVVITGMSGKLPESENLEEFWANLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRFDASFFGVHPKQAHNMDPQLRLLLEVTYEAIVDAGINPASIRGTNTGVWVGVSGSEASEALSRDPETLVGYSMVGCQRAMLANRLSFFFDFKGPSITLDTACSSSLLALQRAYQAIQRGECAMAIVGGVNILLKPNTSVQFMKLGMLSPEGTCKSFDASGNGYCRAEAVMAILLTKKSLARRVYATILNAGTNTDGCKEKGVTFPSGEAQEQLISSLYKPAGLDPETLEYVEAHGTGTKVLLSLEHGLWAPNLHFHNPNPKIPALQDGRLQVVDRPLPVLGGNVGINSFGFGGSNVHVILQPNSQPLPPPAPHAALPRLLRASGRTLEGVQGLLELGLQHSQNLAFVSMLNDIAAPSPAAMPFRGYAVLGSQGGSQEVQQVLAGKRPLWFICSGMGTQWRGMGLSLMRLSRFRDSILRSDEAVKPLGLQVSQLLLSTDEAIFDDMVISFVSLTAIQIALIDLLTSMGLQPDGIIGHSLGEVACGYADGCISQEEAILSAYWRGQCIKEANIPPGAMAAVGLTWEECKQRCPPGIVPACHNCIDTVTISGPQASMLEFVQQLKQEGVFAKEVRTGGMAFHSYFMDAIAPMLLQQLKKVIREPQPRSPRWLSTSIPETQWQESLARTFSAEYNVNNLVSPVLFQEALWRVPEDAVVLEIAPHALLQAVLKRGLKSSCTIIPLMKKDHRDNLEFFLSNVGQLYLTGIDVNPNGLFPPVEFPAPRGTPLISPHIKWDHSQTWDVPTAEDFPSGSSSSSATIYKIDINPESPDHYLVDHCIDGRIIFPGTGYLCLVWKTLARALDQNMEHTPVVFEDVTLHQAVILPKTGIVLLEVRLLEASCTFEVSENGNLIASGKVYQWEDPNPKLFDNRYGPDPATPVDPTTAIHLCRGDVYKELQLQGFNYGPYFQGILEASSEGNTGQLLWKDNWVTFMDTMLQMSILAPSKRSLRLPTRITAIYIHPATHQQKLYTLQDKTQVADVVINRCLDTTVAGGIYISRIHTSVAPRHQQEQLVPILEKFCFTPHVETGCLAGNLALQEELQLCVGLAQALQTRVAQQGIKMVVPGLDGAQAPQEAPQQGLPRLLATACQLQLNGNLQMEMGQILAQERALLCDDPLLSGLLNSPALKACVDTALENMTSLKMKVVEVLAGDGQLYSRIPTLLNTQPLLELDYTATDRHPQALEAAQAKLQQLDITQGQWDPSDPAPSNLGGANLVVCNYALASLGDPATAVGNMVAALKEGGFLLLHTLLRGHPLGETVTFLTCPEPQQGQRHLLSQDEWERLFAGASLYLVALKKSFYGSVLFLCRRLAPLDSPIFLPVEDTSFQWVDSLKNILADSSSRPVWLMAVGCTTSGVVGLVNCLRKEPDGHRIRCVLVSNLNSTSPIPETDPKSLELQKVLQSDLVMNVYRDGAWGAFRHFPLEQDKPEEQTEHAFINVLTRGDLSSIRWVCSPLRHSQPTAPGFQLCTIYYASLNFRDIMLATGKLSPDAIPGNWASRNCLLGMEFSGRDASGKRVMGLVPAEGLATSTLVPQSFLWDVPSNWTLEEAASVPVVYSTAYYALMVRGRMQPGETVLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQSRFPQLNETSFANSRDTSFEQHVLWHTAGKGADLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSKNHPLGMAIFLKNVTFHGILLDSLFEENNTMWQEVSTLLKAGIREGVVQPLKRTVFPRTQAEDAFRYMAQGKHIGKVVLQVREEEQEAVLHGTKPTQMVALCKTFCPAHKSYIITGGLGGFGLELAHWLVERGAQKLVLTSRSGIRTGYQARQVHEWRRQGVQVLVSTSDVSALDGTRSLITEAAQLGPVGGIFNLAVVLRDAMLDNQTPEFFQDVNKPKYNGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQTNYGFANSTMERICEKRRHDGLPGLAVQWGAIADVGLLMELKGTKDKAIGGTLPQRITSCMEVLDLFLNQPHPVLSSFVLAEKATSRGPSGSHQDLVKAVTHILGIRDLATVNLDSSLSDLGLDSLMGVEVRQMLEREHNLLLSMREIRQLTIHKLQEISAQAGTADELTDSTPKFGSPAQSQTQLNLSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSTTVFHSLATKLSIPTYGLQCTGAAPLDSIQSLATYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAQQNAGPTNNSLFLFDGSHTFVMAYTQSYRAKLNPGCEAEAEAEAMCFFMQQFTEAEHSRVLEALLPLGDLEARVAATVELIVQSHAGLDRHALSFAARSFYHKLRAAEEYTPRATYHGNVTLLRAKMGSAYQEGLGADYNLSQVCDGKVSVHIIEGDHRTLLEGSGLESILSIIHSSLAEPRVSVREG", "length": 2481, "header": "tr|A0A3Q1MPB3-1|A0ABI0NT64_BOVIN Computationally mapped isoform of Fatty acid synthase OS=Bos taurus OX=9913 GN=FASN PE=1 SV=2 CANONICAL=A0ABI0NT64-1" }, "locus": { "chromosome": "19", "start_pos": 50794360, "end_pos": 50776602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068989.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068989.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071483.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071483.2" } ] } }, { "isoform_ac": "A0ABI0NT64-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64/entry#A0ABI0NT64-1", "sequence": { "sequence": "MPKPSEAERAAMEEVVITGMSGKLPESENLEEFWANLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRFDASFFGVHPKQAHNMDPQLRLLLEVTYEAIVDAGINPASIRGTNTGVWVGVSGSEASEALSRDPETLVGYSMVGCQRAMLANRLSFFFDFKGPSITLDTACSSSLLALQRAYQAIQRGECAMAIVGGVNILLKPNTSVQFMKLGMLSPEGTCKSFDASGNGYCRAEAVMAILLTKKSLARRVYATILNAGTNTDGCKEKGVTFPSGEAQEQLISSLYKPAGLDPETLEYVEAHGTGTKVGDPQELNGIVQALCGTRQSPLRIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHNPNPKIPALQDGRLQVVDRPLPVLGGNVGINSFGFGGSNVHVILQPNSQPLPPPAPHAALPRLLRASGRTLEGVQGLLELGLQHSQNLAFVSMLNDIAAPSPAAMPFRGYAVLGSQGGSQEVQQVLAGKRPLWFICSGMGTQWRGMGLSLMRLSRFRDSILRSDEAVKPLGLQVSQLLLSTDEAIFDDMVISFVSLTAIQIALIDLLTSMGLQPDGIIGHSLGEVACGYADGCISQEEAILSAYWRGQCIKEANIPPGAMAAVGLTWEECKQRCPPGIVPACHNCIDTVTISGPQASMLEFVQQLKQEGVFAKEVRTGGMAFHSYFMDAIAPMLLQQLKKVIREPQPRSPRWLSTSIPETQWQESLARTFSAEYNVNNLVSPVLFQEALWRVPEDAVVLEIAPHALLQAVLKRGLKSSCTIIPLMKKDHRDNLEFFLSNVGQLYLTGIDVNPNGLFPPVEFPAPRGTPLISPHIKWDHSQTWDVPTAEDFPSGSSSSSATIYKIDINPESPDHYLVDHCIDGRIIFPGTGYLCLVWKTLARALDQNMEHTPVVFEDVTLHQAVILPKTGIVLLEVRLLEASCTFEVSENGNLIASGKVYQWEDPNPKLFDNRYGPDPATPVDPTTAIHLCRGDVYKELQLQGFNYGPYFQGILEASSEGNTGQLLWKDNWVTFMDTMLQMSILAPSKRSLRLPTRITAIYIHPATHQQKLYTLQDKTQVADVVINRCLDTTVAGGIYISRIHTSVAPRHQQEQLVPILEKFCFTPHVETGCLAGNLALQEELQLCVGLAQALQTRVAQQGIKMVVPGLDGAQAPQEAPQQGLPRLLATACQLQLNGNLQMEMGQILAQERALLCDDPLLSGLLNSPALKACVDTALENMTSLKMKVVEVLAGDGQLYSRIPTLLNTQPLLELDYTATDRHPQALEAAQAKLQQLDITQGQWDPSDPAPSNLGGANLVVCNYALASLGDPATAVGNMVAALKEGGFLLLHTLLRGHPLGETVTFLTCPEPQQGQRHLLSQDEWERLFAGASLYLVALKKSFYGSVLFLCRRLAPLDSPIFLPVEDTSFQWVDSLKNILADSSSRPVWLMAVGCTTSGVVGLVNCLRKEPDGHRIRCVLVSNLNSTSPIPETDPKSLELQKVLQSDLVMNVYRDGAWGAFRHFPLEQDKPEEQTEHAFINVLTRGDLSSIRWVCSPLRHSQPTAPGFQLCTIYYASLNFRDIMLATGKLSPDAIPGNWASRNCLLGMEFSGRDASGKRVMGLVPAEGLATSTLVPQSFLWDVPSNWTLEEAASVPVVYSTAYYALMVRGRMQPGETVLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQSRFPQLNETSFANSRDTSFEQHVLWHTAGKGADLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSKNHPLGMAIFLKNVTFHGILLDSLFEENNTMWQEVSTLLKAGIREGVVQPLKRTVFPRTQAEDAFRYMAQGKHIGKVVLQVREEEQEAVLHGTKPTQMVALCKTFCPAHKSYIITGGLGGFGLELAHWLVERGAQKLVLTSRSGIRTGYQARQVHEWRRQGVQVLVSTSDVSALDGTRSLITEAAQLGPVGGIFNLAVVLRDAMLDNQTPEFFQDVNKPKYNGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQTNYGFANSTMERICEKRRHDGLPGLAVQWGAIADVGLLMELKGTKDKAIGGTLPQRITSCMEVLDLFLNQPHPVLSSFVLAEKATSRGPSGSHQDLVKAVTHILGIRDLATVNLDSSLSDLGLDSLMGVEVRQMLEREHNLLLSMREIRQLTIHKLQEISAQAGTADELTDSTPKFGSPAQSQTQLNLSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSTTVFHSLATKLSIPTYGLQCTGAAPLDSIQSLATYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAQQNAGPTNNSLFLFDGSHTFVMAYTQSYRAKLNPGCEAEAEAEAMCFFMQQFTEAEHSRVLEALLPLGDLEARVAATVELIVQSHAGLDRHALSFAARSFYHKLRAAEEYTPRATYHGNVTLLRAKMGSAYQEGLGADYNLSQVCDGKVSVHIIEGDHRTLLEGSGLESILSIIHSSLAEPRVSVREG", "length": 2526, "header": "tr|A0ABI0NT64-1|A0ABI0NT64_BOVIN Isoform 1 of Fatty acid synthase OS=Bos taurus OX=9913 GN=FASN PE=1 SV=1 CANONICAL=A0ABI0NT64-1" }, "locus": { "chromosome": "19", "start_pos": 50794360, "end_pos": 50776602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146519.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146519.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106548.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106548.1" } ] } }, { "isoform_ac": "F1N647-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64/entry#F1N647-1", "sequence": { "sequence": "MEEVVITGMSGKLPESENLEEFWANLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRFDASFFGVHPKQAHNMDPQLRLLLEVTYEAIVDAGPSITLDTACSSSLLALQRAYQAIQRGECAMAIVGGVNILLKPNTSVQFMKLGMLSPEGTCKSFDASGNGYCRAEAVMAILLTKKSLARRVYATILNAGTNTDGCKEKGVTFPSGEAQEQLISSLYKPAGLDPETLEYVEAHGTGTKVGDPQELNGIVQALCGTRQSPLRIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHNPNPKIPALQDGRLQVVDRPLPVLGGNVGINSFGFGGSNVHVILQPNSQPLPPPAPHAALPRLLRASGRTLEGVQGLLELGLQHSQNLAFVSMLNDIAAPSPAAMPFRGYAVLGSQGGSQEVQQVLAGKRPLWFICSGMGTQWRGMGLSLMRLSRFRDSILRSDEAVKPLGLQVSQLLLSTDEAIFDDMVISFVSLTAIQIALIDLLTSMGLQPDGIIGHSLGEVACGYADGCISQEEAILSAYWRGQCIKEANIPPGAMAAVGLTWEECKQRCPPGIVPACHNCIDTVTISGPQASMLEFVQQLKQEGVFAKEVRTGGMAFHSYFMDAIAPMLLQQLKKVIREPQPRSPRWLSTSIPETQWQESLARTFSAEYNVNNLVSPVLFQEALWRVPEDAVVLEIAPHALLQAVLKRGLKSSCTIIPLMKKDHRDNLEFFLSNVGQLYLTGIDVNPNGLFPPVEFPAPRGTPLISPHIKWDHSQTWDVPTAEDFPSGSSSSSATIYKIDINPESPDHYLVDHCIDGRIIFPGTGYLCLVWKTLARALDQNMEHTPVVFEDVTLHQAVILPKTGIVLLEVRLLEASCTFEVSENGNLIASGKVYQWEDPNPKLFDNRYGPDPATPVDPTTAIHLCRGDVYKELQLQGFNYGPYFQGILEASSEGNTGQLLWKDNWVTFMDTMLQMSILAPSKRSLRLPTRITAIYIHPATHQQKLYTLQDKTQVADVVINRCLDTTVAGGIYISRIHTSVAPRHQQEQLVPILEKFCFTPHVETGCLAGNLALQEELQLCVGLAQALQTRVAQQGIKMVVPGLDGAQAPQEAPQQGLPRLLATACQLQLNGNLQMEMGQILAQERALLCDDPLLSGLLNSPALKACVDTALENMTSLKMKVVEVLAGDGQLYSRIPTLLNTQPLLELDYTATDRHPQALEAAQAKLQQLDITQGQWDPSDPAPSNLGGANLVVCNYALASLGDPATAVGNMVAALKEGGFLLLHTLLRGHPLGETVTFLTCPEPQQGQRHLLSQDEWERLFAGASLYLVALKKSFYGSVLFLCRRLAPLDSPIFLPVEDTSFQWVDSLKNILADSSSRPVWLMAVGCTTSGVVGLVNCLRKEPDGHRIRCVLVSNLNSTSPIPETDPKSLELQKVLQSDLVMNVYRDGAWGAFRHFPLEQDKPEEQTEHAFINVLTRGDLSSIRWVCSPLRHSQPTAPGFQLCTIYYASLNFRDIMLATGKLSPDAIPGNWASRNCLLGMEFSGRDASGKRVMGLVPAEGLATSTLVPQSFLWDVPSNWTLEEAASVPVVYSTAYYALMVRGRMQPGETVLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQSRFPQLNETSFANSRDTSFEQHVLWHTAGKGADLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSKNHPLGMAIFLKNVTFHGILLDSLFEENNTMWQEVSTLLKAGIREGVVQPLKRTVFPRTQAEDAFRYMAQGKHIGKVVLQVREEEQEAVLHGTKPTQMVALCKTFCPAHKSYIITGGLGGFGLELAHWLVERGAQKLVLTSRSGIRTGYQARQVHEWRRQGVQVLVSTSDVSALDGTRSLITEAAQLGPVGGIFNLAVVLRDAMLDNQTPEFFQDVNKPKYNGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQTNYGFANSTMERICEKRRHDGLPGLAVQWGAIADVGLLMELKGTKDKAIGGTLPQRITSCMEVLDLFLNQPHPVLSSFVLAEKATSRGPSGSHQDLVKAVTHILGIRDLATVNLDSSLSDLGLDSLMGVEVRQMLEREHNLLLSMREIRQLTIHKLQEISAQAGTADELTDSTPKFGSPAQSQTQLNLSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSTTVFHSLATKLSIPTYGLQCTGAAPLDSIQSLATYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAQQNAGPTNNSLFLFDGSHTFVMAYTQSYRAKLNPGCEAEAEAEAMCFFMQQFTEAEHSRVLEALLPLGDLEARVAATVELIVQSHAGLDRHALSFAARSFYHKLRAAEEYTPRATYHGNVTLLRAKMGSAYQEGLGADYNLSQVCDGKVSVHIIEGDHRTLLEGSGLESILSIIHSSLAEPRVSVREG", "length": 2457, "header": "tr|F1N647-1|A0ABI0NT64_BOVIN Computationally mapped isoform of Fatty acid synthase OS=Bos taurus OX=9913 GN=FASN PE=1 SV=4 CANONICAL=A0ABI0NT64-1" }, "locus": { "chromosome": "19", "start_pos": 50794360, "end_pos": 50778202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021260.7", "url": "https://www.ensembl.org/id/ENSBTAT00000021260.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021260.6", "url": "https://www.ensembl.org/id/ENSBTAP00000021260.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 995, "start_aa": "Thr", "end_pos": 995, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr995", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-199220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-199220", "resource": "Reactome", "description": "Vitamin B5 (pantothenate) metabolism" }, { "id": "R-BTA-75105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75105", "resource": "Reactome", "description": "Fatty acyl-CoA biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "B7Z001-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPLQLNLLQAVDQPHPVAFKPNNCSTHQPQHSPSTQNNGKSARANRRRRRRRNKQQQNSQQPDAFRDTDAQLTPSTSSSTPHSAPNDRQDHLNSQFNPESINMPARFAEEVITAEPAQRAAPQLDLGGGHYVPRQQHLNDEIAITGFSGRLPESSTIEEFKQNLFDGVDMVNDDPRRWERGLYGLPDRIGKLKDSDLENFDQQFFGVHQKQAECMDPLLRMLLELTHEAIIDAGLNPSDLRGSRTGVYIGVSNSETEQHWCSDADRVNGYGLTGCARAMFANRISFTFDFKGPSYSIDTACSSSLYALEQAFSDMREGKVDNALVAGAGLILKPTMSLQFKRLNMLSPDGSCKAFDESGNGYVRSDGCVVLLLQRTSAARRVYASILNVRTNTDGFKEQGITYPIGKMQNRLIRETYEEIGLNPADVVYVEAHGTGTKVGDPQEVNSITDFFCKDRTTPLLIGSVKSNMGHSEPASGVCSVAKILIAMEEGVIPGNLHYNKPNPDLYGLVDGRLKVVDRNLPWNGGIIGLNSFGFGGANAHVILKSNPKPKALTPKDGALKVVLASGRTFEAVEQLLESASTNADDDEYLQLINEIHSKAIPNHFFRGYGVVSSKGTHQREVIESNDDKRPIWYIYSGMGSQWASMAKDLMKIEAFAKTIQRCADVLKPEGVDLIDVLTRSTDKSFENILNSFISIAAMQVALTDLLSSLGIHPDGIVGHSVGELGCAYADGCFTPEQTVLAAYWRGKSILDTQLAKGKMAAVGLSWEDAHSRVPSDCFPVCHNSEDNCTISGPEASIEALVAKLNAEGVFAKAVNSSGYAFHSKYIAEAGPKLRKSLEKIIPNAKNRTARWISTSIPESAWNTPVAKQSSAAYHVNNLLSPVLFHEALQHVPKNAISVEIAPHGLLQAILKRALGPDATNLSLVKRGHENNVEFFLTNVGKLFAAGAQPQVLTLVRPISYPVGRGTPMLNSKVGWDHTQKWLVAKFGKETSSGETIVEVDLSKEDDAFLAGHTIDGRILFPATGYMTLAWQTFAKMQGSEFHKTPVVMENLVFHRATILNKNAVVKFGINFFDGTGAFEICESGSLAVSGKITIPESIDNEELPLEEQTPSAVAKELGTNDVYKELRLRGYDYGGIFRGIVRSDTVASTGKLQWVDNWISFMDTMLQFSILSKNLRELYLPTRIERAVINPAKHFELLSALTKEEQVETGLPVQWYSDINVIKSAGVELRGLKANLAQRRPGTQAPPTLERYQFVPNINTTDLNENSEKARLHALDVAIQVIIENSSGAVKLKGVELANGRNPDVLVANRLLQIIEGEPVLTGDVAVVTSNNNEETITAALGDSGVRVVSKDVLKEPVEQNCHFVFGIDVLSRPDTKTLENSIASIRENGFLILEETLPTYTKTGRALLTKFGFVAVQEQSLGATRVLVLARKAVDLKTRKSVVVVATEQNFNWVDDLKAALATAATEEQYVYVVCQGEELFGAVGLMTCIKNENGGKLARLVFVQDAKAEKFSLTSTLYRQQLEKDLISNVLKNGAWGTFRHLKLETQQATLQVEHAYVNALVKGDLASLKWIEAAQADTAATVDKNLETCTVYYAPINFRDVMLTSGKLAADALPGDLAEQDCVLGLEFAGRDTQGRRVMAMVPAKSLATTCVASKRMMWQIPEKWTMEEASTVPCVYSTVYYALVVRGQMKKGEKILIHAGSGGVGQAAISVALAHGLTVFTTVGSKEKREFLLKRFPKLQERNIGNSRDTSFEQLVLRETKGRGVDLVLNSLSEEKLQASIRCLGLNGRFLEIGKFDLSNNSPLGMSVFLKNTSFHGILLDSVMEGEEEMQNQVVSLVAEGIKTGAVVPLPTSVFNDQQVEQAFRFMASGKHIGKVVIKVRDEEAGKKALQPKPRLINAIPRTYMHPEKSYILVGGLGGFGLELTNWLVTRGARYIVLTSRSGVKTGYQGLMIRRWQERGVKVVIDTSDVTTAAGAKKLLENSNKLALVGGIFNLAAVLRDALIEDQTAKDFKTVADPKVTATKYLDQFSRDICTELDYFICFSSVSCGRGNIGQTNYGLANSAMERICEQRQVSGFPGTAIQWGAIGDTGLVLENLGDNDTVIGGTLPQRMPSCLQTIDLFLQQPHPVVASMVVAEKRKSDQSAGVSLIATIANILGLRDTKNIQDGASLADLGMDSLMSAEIKQTLERNFDIVLSAQEIRQLTFGALKAMDGGADVKPAAAAPAAAAGVPEANITSGGSSRTASPMGDGTQVVFTTSLIPTEAIVQLDTKAPANSKQSPIFFISPIEGFASALEPLAKRLEVPAYGLQYTEAVPSDSLESAAKFFIKQLRTVQPKGPYKLAGYSFGCLLTYVMAGILEETNEVANVIMLDGAPSYVNWYTSSFKQRYTDGTNADNDNQSYGLAYFGIVLANIDYKALVRLLIVIPTWEEKLERFAELMSNEITQPVETIKKSATLFYKKLELADGYQPTLKLKTNVTLVKPTDNSAKLDEDYRLKEVCTKPVEVHTVEGNHRTFLIEDQSLKTIQSILKRLFN", "length": 2540 }, "evidence": [ { "id": "A0ABI0NT64", "url": "https://omabrowser.org/oma/group/A0ABI0NT64/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "G3GXD7-1", "protein_name": "Fatty acid synthase", "gene_name": "Fasn", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLKDLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALSRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDSACSSSLLALQSAYQAIRNGECPAALVGGINVLLKPNTSVQFMKLGMLSPEGTCKSFDDSGNGYCRSEAVVAVLLTKKSLARRVYATILNAGTNTDGCKEQGVTFPSGEAQEQLIQSLYRPAGLAPESLEYIEAHGTGTKVGDPQELNGIVRSLCASRQGPLLIGSTKSNMGHPEPASGLAALTKVLLSLENGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGNVGINSFGFGGANVHVILQPNTQQAPAPAPHAALPHLLHASGRTAEAVQGLLEQGRKHSQDMAFVSMLNDIAATPTAAMPFRGYTVLGVEGDVQEVQQVPASKRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEAVKPLGIKVSDLLLSTDESTFDDIVHAFVGLTAIQIALIDLLTSVGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDAHLPPGSMAAVGLSWEECKQRCPSGVVPACHNSEDTVTISGPQAAVSEFVEQLKQEGVFAKEVRTGGLAFHSYFMEGIAPMLLQALKKVIREPRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVLLEIAPHALLQAVLKRGVKSSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGIDVNPNALFPPVDFPAPRGTPLISPHIKWDHSQTWDVPAAEDFPNGSCSSSATVYSIDASPESPDHYLVDHCIDGRVLFPATGYLYLVWKTLARNLSLSLEETPVVFEDVTIHQATILPKTGTVPLEVRLLEASRAFEVSENGNLIVSGKVYQWEDPDSKLFDHPHVLNPPESTPVSRLTQTEVYKELRLRGYDYGPHFQGIVEASLEGEQGKLLWKGNWVTFLDTMLQVSILGVSQQSLRLPVRVTAIHIDPATHLQKVYTLEGENQVADVTTSLCLDSTVSGGVRISRLHTTAAPRRQQEQLVPTLEKFIFTPHVEDGCLSENTTLQRELQLCKDLAQALQTKATQQGLKMTVPGLEGPPQHGLSRLLAAACQLQLNGNLQLELGEALAQERVLLPEDPLISGLLNSQALKACVDTALENLPSLKMKVVEVLSGEGRLYSRIPSLLNTQPMLQLEYTATDLHPEALKDVQAKLQQHDIAQGQWNPEDPAPSNLGALDLVVCSCAVATLGNPALALSNMVAALKEGGFLLMHTVLRGHSLGETLACLPSAVQPGPSLSQEEWESLFSKKGLHLVGLKKSFYGTALFLCRRATLQDNPLFLPVEDTSYQWVDSLKRILAESSSQPVWLTATDCPTSGVVGLVNCLRKEPGGHRIRCILLSNLSTSSHTPKMGPGSSELQKVLKNDLVMNVYRDGAWGAFRHFLLEQDKPEEQTAHAFVNVLTRGDLASIRWVCSPLKHAQPTSPGTQLCTVYYASLNFRDIMLATGKLPPDAIPGKWASRDCMLGMEFSGRDKCGRRVMGLVPAEGLATSVLLSPDFLWEVPSSWTLEEAASVPVVYTTAYYSLVVRGRVQRGETVLIHSGSGGVGQAAISIALSLGCRVFTTVGSAEKRAYLQARFPQLDDTSFANSRDTSFEQHVLLHTGGKGVNLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHPLGMAIFLKNVTFHGILLDALFEEANDSWREVAALLQAGIRDGVVKPLKCTVFPKDQVEDAFRFMAQGKHIGKVLVQVREEEPEAVLPGAQPTLIPAISKTFCPAHKSYIITGGLGGFGLELARWLVLRGAQRLVLTSRSGIRTGYQAKQVQEWRRQGIHVLVSTSNASSLEGARALITEATKLGPVGGVFNLAMVLRDAMLENQTPELFQDVNKPKYNGTLNLDRTTREACPELDYFVAFSSVSCGRGNAGQTNYGFANSAMERICEQRRHDGLPGLAVQWGAIGDVGIVLEAMGTNDTVIGGTLPQRIASCMEVLDLFLNQPYAVLSSFVLAEKKAVAQGDGEAQRDLVKAVAHILGIRDLAGVNLDSSLADLGLDSLMGVEVRQILEHEHDLVLPMREVRQLTLRKLEELSSKAGSASETTAPKSKNDTALKQTQLNLSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSTTVFHSLAAKLSVPTYGLQCTQAAPLDSIPDLAAYYIDCIKQVQPEGPYRVAGYSFGACVAFEMCSQLQAQQGPTPTHNSLFLFDGSHTYVLAYTQSYRARMTPGCEAEAEAEAICYFIKQFTDAEHNKVLEALLSLKSLEDRVTAAVDLITKSHHSLDRRELSFAALSFYQKLRAADQYKPKAKYHGNVTLLRAKTGGTYGEDLGADYNLSQVCDGKVSVHIIEGDHRTLLEGSGLESIINIIHSSLAEPRVSVREG", "length": 2503 }, "evidence": [ { "id": "A0ABI0NT64", "url": "https://omabrowser.org/oma/group/A0ABI0NT64/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LCW1-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEEVVIAGMSGKLPESENLEEFWANLIGGVDMVTADDRRWKAGLYGLPRRMGKLKDLSRFDASFFGVHSKQANTMDPQLRMLLEVTYEAIVDGGINPASLRGTSTGVWVGVSSSDASEALSRDPETLVGYSMIGCQRAMMANRVSFFFDFKGPSITIDTACSSSLLALQSAYQAIRGGECSAAVVGGLNVLLKPNSSLQFMKLGMLSQDGTCRSFDAEGTGYCRAEAVVAVLLTKKSLARRVYATILNAGTNTDGSKEQGVTFPSGDVQEQLIRSLYAPAGPDPESLEYIEAHGTGTKVGDPQELNGIVNALCATRREPLLIGSTKSNMGHPEPASGVAALIKVLLSLEHGVWAPNLHYHTPNPEIPALQDGRLQVVDRPLPIRGGNVGINSFGFGGSNVHVILQPNSRPAPPPAQHAALPRLLQASGRTLEAVQTLLEQGLRHSRDLAFVGMLNEIAAVSPVAMPFRGYAVLGGEAGSQEVQQVPGSKRPVWFICSGMGAQWQGMGLSLMRLDRFRDSILRSDQALKPLGLRVSDLLLSTDEAVLDDIVSSFVSLTSIQIALIDLLTSLGLQPDGIIGHSLGEVACGYADGCLTQEEAVLSSYWRGYCIKEANVLPGAMAAVGLSWEECKQRCPPGIVPACHNSKDTVTISGPQAAMSEFLQQLKREDVFVKEVRTGGIAFHSYFMESIAPTLLRQLRKVILDPKPRSKRWLSTSIPEAQWQGSLARTFSAEYSVNNLVSPVLFQEALQHVPAHAVVVEIAPHALLQAVLKRSLESSCTIIPLMKKDHRDNLEFFLSNVGRLHLAGVSVNPNGLFPPVEFPAPRTPLISPHIKWDHSQAWDVPSAADFPSGSSCSSVAVYKFDVSPESPDHYLVDHCIDGRVLFPGTGYLWLTWKTLARALSQNLEETPVVFEDVTLHQATILPKTGTVSLEVRLLEASHAFEVSDSNGSLIASGKVYQWESPDPKLFDTRAAVDPADSTAEFRLSQGDVYKDLRLRGYDYGPFFQLVLESDLEGNRGRLQWNDSWVSFLDAMLHMSILAPGQLGLYLPTRFTSIRIDPVTHRQKLYTLQDTTQAADVVVDRNLNTVVAGGALFLGAHSSVAPRRPQEHLKPILEKFCFTPHVESGCLAGNTALQEELQLCRGLAQALQTKVAQQGLKMVVPGLDGAQAPREAPQQSLPRLLAAACQLQLNGNLQLELGQVLAQERPLLCDDPLLSGLLDAPALKACVDTALENMASPKMKVVEVLAGDGQLYSRIPALLNTQPVMDLDYTATDRNPQALEAAQAKLEQLHVTQGQWDPANPAPGSLGKADLLVCNCALATLGDPAVAVGNMAATLKEGFLLLHTLLAGHPLGEMVGFLTSPEQGGRHLLSQDQWESLFAGASLHLVALKRSFYGSVLFLCRQQTPQDSPVFLSVEDTSFRWVNSLKDILADASSRPVWLMAVGCSTSGVVGMVNCLRKEPGGHRIRCVLVSNLSSTSPAPEMHPSSSELQKVLQGDLVMNVYRDGAWGAFRHFPLEQDRPEKQTEHAFVNVLSRGDLSSIRWVCSPLHYALPASCQDRLCSVYYTSLNFRDVMLATGKLSPDSIPGKWLTRDCMLGMEFSGRDASGRRVMGMVPAGGLATSVLLLPHATWEVPSTWTLEEAASVPIVYTTAYYSLVVRGRMQPGESVLIHSGSGGVGQAAIAIALSRGCRVFTTVGSAEKRAYLQARFPQLDETCFANSRDTSFEQHVLRHTAGKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHALGMAVFLKNVTFHGILLDSLFEEGGATWQEVSELLKAGIQEGVVQPLKCTVFPRTKVEAAFRYMAQGKHIGKVVIQVREEEQGPAPRGLPPIALTGLSKTFCPPHKSYVITGGLGGFGLQLAQWLRLRGAQKLVLTSRSGIRTGYQARQVREWRRQGVQVLVSTSNASSLDGARSLITEATQLGPVGGVFNLAMVLRDAVLENQTPEFFQDVSKPKYSGTANLDRVTREACPELDYFVIFSSVSCGRGNAGQANYGFANSAMERICEKRRHDGLPGLAVQWGAIGDVGVVLETMGTNDTVIGGTLPQRIASCLEVLDLFLSQPHPVLSSFVLAEKKAAAPRDGSSQKDLVKAVAHILGIRDVASINPDSTLVDLGLDSLMGVEVRQILEREHDLVLSMREVRQLSLRKLQELSSKTSTDADPATPTSHEDSPVRQQATLNLSTLLVNPEGPTLTRLNSVQSAERPLFLVHPIEGSITVFHGLAAKLSIPTYGLQCTGAAPLDSIQSLASYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAQQSATPGNHSLFLFDGSHTFVLAYTQSVRAKMTPGCEAEAEAKAMYFFVQQFTDMEQGKVLEALIPLQGLEARVAATVDLITQSHAGLDRHALSFAARSFYQKLRAAENYWPQATYHGNVTLLRAKTGGAYGEDLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESILSIIHSCLAEPRVSVREG", "length": 2510 }, "evidence": [ { "id": "A0ABI0NT64", "url": "https://omabrowser.org/oma/group/A0ABI0NT64/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P19096-1", "protein_name": "Fatty acid synthase", "gene_name": "Fasn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEVVIAGMSGKLPESENLQEFWANLIGGVDMVTDDDRRWKAGLYGLPKRSGKLKDLSKFDASFFGVHPKQAHTMDPQLRLLLEVSYEAIVDGGINPASLRGTNTGVWVGVSGSEASEALSRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGECPAALVGGINLLLKPNTSVQFMKLGMLSPDGTCRSFDDSGSGYCRSEAVVAVLLTKKSLARRVYATILNAGTNTDGSKEQGVTFPSGEVQEQLICSLYQPAGLAPESLEYIEAHGTGTKVGDPQELNGITRSLCAFRQAPLLIGSTKSNMGHPEPASGLAALTKVLLSLEHGVWAPNLHFHNPNPEIPALLDGRLQVVDRPLPVRGGNVGINSFGFGGSNVHVILQPNTRQAPAPTAHAALPHLLHASGRTLEAVQDLLEQGRQHSQDLAFVSMLNDIAATPTAAMPFRGYTVLGVEGRVQEVQQVSTNKRPLWFICSGMGTQWRGMGLSLMRLDSFRESILRSDEAVKPLGVKVSDLLLSTDERTFDDIVHAFVSLTAIQIALIDLLTSVGLKPDGIIGHSLGEVACGYADGCLSQREAVLAAYWRGQCIKDAHLPPGSMAAVGLSWEECKQRCPAGVVPACHNSEDTVTISGPQAAVNEFVEQLKQEGVFAKEVRTGGLAFHSYFMEGIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQSSLARTSSAEYNVNNLVSPVLFQEALWHIPEHAVVLEIAPHALLQAVLKRGVKSSCTIIPLMKRDHKDNLEFFLTNLGKVHLTGINVNPNALFPPVEFPAPRGTPLISPHIKWDHSQTWDVPVAEDFPNGSSSSSATVYSIDASPESPDHYLVDHCIDGRVIFPGTGYLCLVWKTLARSLGLSLEETPVVFENVSFHQATILPKTGTVALEVRLLEASHAFEVSDTGNLIVSGKVYLWEDPNSKLFDHPEVPTPPESASVSRLTQGEVYKELRLRGYDYGPQFQGICEATLEGEQGKLLWKDNWVTFMDTMLQVSILGSSQQSLQLPTRVTAIYIDPATHRQKVYRLKEDTQVADVTTSRCLGITVSGGIHISRLQTTATSRRQQEQLVPTLEKFVFTPHMEAECLSESTALQKELQLCKGLARALQTKATQQGLKAAMLGQEDPPQHGLPRLLAAACQLQLNGNLQLELGEALAQERLLLPEDPLISGLLNSQALKACVDTALENLSTLKMKVAEVLAGEGHLYSRIPALLNTQPMLQLEYTATDRHPQALKDVQTKLQQHDVAQGQWNPSDPAPSSLGALDLLVCNCALATLGDPALALDNMVAALKEGGFLLVHTVLKGHALGETLACLPSEVQPAPSLLSQEEWESLFSRKALHLVGLKRSFYGTALFLCRRAIPQEKPIFLSVEDTSFQWVDSLKSTLATSSSQPVWLTAMDCPTSGVVGLVNCLRKEPGGHRIRCILLSNLSNTSHAPKLDPGSPELQQVLKHDLVMNVYRDGAWGAFRHFQLEQDKPKEQTAHAFVNVLTRGDLASIRWVSSPLKHTQPSSSGAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWASRDCMLGMEFSGRDRCGRRVMGLVPAEGLATSVLLSSDFLWDVPSSWTLEEAASVPVVYTTAYYSLVVRGRIQRGETVLIHSGSGGVGQAAISIALSLGCRVFTTVGSAEKRAYLQARFPQLDDTSFANSRDTSFEQHVLLHTGGKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHPLGMAIFLKNVTFHGILLDALFEEANDSWREVAALLKAGIRDGVVKPLKCTVFPKAQVEDAFRYMAQGKHIGKVLVQVREEEPEAVLPGAQPTLISAISKTFCPAHKSYIITGGLGGFGLELARWLVLRGAQRLVLTSRSGIRTGYQAKHIREWRRQGIQVLVSTSNVSSLEGARALIAEATKLGPVGGVFNLAMVLRDAMLENQTPELFQDVNKPKYNGTLNLDRATREACPELDYFVAFSSVSCGRGNAGQTNYGFANSTMERICEQRRHDGLPGLAVQWGAIGDVGIVLEAMGTNDTVIGGTLPQRISSCMEVLDLFLNQPHAVLSSFVLAEKKAVAHGDGDTQRDLVKAVAHILGIRDLAGINLDSTLADLGLDSLMGVEVRQILEREHDLVLPMREVRQLTLRKLQEMSSKTDSATDTTAPKSRSDTSLKQNQLNLSTLLVNPEGPTLTQLNSVQSSERPLFLVHPIEGSTTVFHSLAAKLSVPTYGLQCTQAAPLDSIPNLAAYYIDCIKQVQPEGPYRIAGYSFGACVAFEMCSQLQAQQGPAPTHNNLFLFDGSHTYVLAYTQSYRAKMTPGCEAEAEAEALCFFIKQFLDVEHSKVLEALLPLKSLEDRVAASVDLITKSHHSLDRRELSFAAVSFYHKLRAADQYKPKAKYHGNVTLLRAKTGGTYGEDLGADYNLSQVCDGKVSVHIIEGDHRTLLEGSGLESIINIIHSSLAEPRVSVREG", "length": 2504 }, "evidence": [ { "id": "A0ABI0NT64", "url": "https://omabrowser.org/oma/group/A0ABI0NT64/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRFDASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEALSRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQCPAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLARRVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVGDPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHSPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNTQPPPAPAPHATLPRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGPEVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLSTDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAVLAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFEFVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPEAQWHSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCTIIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSLAWDVPAAEDFPNGSGSPSAAIYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLARALGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQWDDPDPRLFDHPESPTPNPTEPLFLAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRLLWKDNWVSFMDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQVADVVVSRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHTEEGCLSERAALQEELQLCKGLVQALQTKVTQQGLKMVVPGLDGAQIPRDPSQQELPRLLSAACRLQLNGNLQLELAQVLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLLSPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVAALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESLFSRVSLRLVGLKKSFYGSTLFLCRRPTPQDSPIFLPVDDTSFRWVESLKGILADEDSSRPVWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGDLVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPGAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFFNESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEEPEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGIRTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDGLLENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSAMERICEKRRHEGLPGLAVQWGAIGDVGILVETMSTNDTIVSGTLPQRMASCLEVLDLFLNQPHMVLSSFVLAEKAAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSVEVRQTLERELNLVLSVREVRQLTLRKLQELSSKADEASELACPTPKEDGLAQQQTQLNLRSLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLDSIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGSPTYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAAVDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG", "length": 2511 }, "evidence": [ { "id": "A0ABI0NT64", "url": "https://omabrowser.org/oma/group/A0ABI0NT64/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54FI3-1", "protein_name": "Polyketide synthase 37", "gene_name": "StlB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNKSINDLSGNSNNNIANSNINNYNNLIKKEPIAIIGIGCRFPGNVSNYSDFVNIIKNGSDCLTKIPDDRWNADIISRKQWKLNNRIGGYLKNIDQFDNQFFGISPKEAQHIDPQQRLLLHLAIETLEDGKISLDEIKGKKVGVFIGSSSGDYLRGFDSSEINQFTTPGTNSSFLSNRLSYFLDVNGPSMTVNTACSASMVAIHLGLQSLWNGESELSMVGGVNIISSPLQSLDFGKAGLLNQETDGRCYSFDPRASGYVRSEGGGILLLKPLSAALRDNDEIYSLLLNSANNSNGKTPTGITSPRSLCQEKLIQQLLRESSDQFSIDDIGYFECHGTGTQMGDLNEITAIGKSIGMLKSHDDPLIIGSVKASIGHLEGASGICGVIKSIICLKEKILPQQCKFSSYNPKIPFETLNLKVLTKTQPWNNSKRICGVNSFGVGGSNSSLFLSSFDKSTTITEPTTTTTIESLPSSSSSFDNLSVSSSISTNNDNDKVSNIVNNRYGSSIDVITLSVTSPDKEDLKIRANDVLESIKTLDDNFKIRDISNLTNIRTSHFSNRVAIIGDSIDSIKLNLQSFIKGENNNNKSIILPLINNGNNNNNNNNNSSGSSSSSSNNNNICFIFSGQGQQWNKMIFDLYENNKTFKNEMNNFSKQFEMISGWSIIDKLYNSGGGGNEELINETWLAQPSIVAVQYSLIKLFSKDIGIEGSIVLGHSLGELMAAYYCGIINDFNDLLKLLYIRSTLQNKTNGSGRMHVCLSSKAEIEQLISQLGFNGRIVICGNNTMKSCTISGDNESMNQFTKLISSQQYGSVVHKEVRTNSAFHSHQMDIIKDEFFKLFNQYFPTNQISTNQIYDGKSFYSTCYGKYLTPIECKQLLSSPNYWWKNIRESVLFKESIEQILQNHQQSLTFIEITCHPILNYFLSQLLKSSSKSNTLLLSTLSKNSNSIDQLLILCSKLYVNNLSSIKWNWFYDKQQQQQSESLVSSNFKLPGRRWKLEKYWIENCQRQMDRIKPPMFISLDRKLFSVTPSFEVRLNQDRFQYLNDHQIQDIPLVPFSFYIELVYASIFNSISTTTTNTTASTMFEIENFTIDSSIIIDQKKSTLIGINFNSDLTKFEIGSINSIGSGSSSNNNFIENKWKIHSNGIIKYGTNYLKSNSKSNSFNESTTTTTTTTTTTKCFKSFNSNEFYNEIIKYNYNYKSTFQCVKEFKQFDKQGTFYYSEIQFKKNDKQVIDQLLSKQLPSDFRCIHPCLLDAVLQSAIIPATNKTNCSWIPIKIGKLSVNIPSNSYFNFKDQLLYCLIKPSTSTSTSPSTYFSSDIQVFDKKNNNLICELTNLEFKGINSSSSSSSSSSTINSNVEANYESKIEETNHDEDEDEELPLVSEYVWCKEELINQSIKFTDNYQTVIFCSTNLNGNDLLDSIITSALENGHDENKIFIVSPPPVESDQYNNRIIINYTNNESDFDALFAIINSTTSISGKSGLFSTRFIILPNFNSITFSSGNSTPLITNVNGNGNGKSCGGGGGSTNNTISNSSSSISSIDNGNNEDEEMVLKSFNDSNLSLFHLQKSIIKNNIKGRLFLITNGGQSISSSTPTSTYNDQSYVNLSQYQLIGQIRVFSNEYPIMECSMIDIQDSTRIDLITDQLNSTKLSKLEIAFRDNIGYSYKLLKPSIFDNSSLPSSSSEIETTATTKDEEKNNSINYNNNYYRVELSDNGIISDLKIKQFRQMKCGVGQVLVRVEMCTLNFRDILKSLGRDYDPIHLNSMGDEFSGKVIEIGEGVNNLSVGQYVFGINMSKSMGSFVCCNSDLVFPIPIPTPSSSSSSNENIDDQEIISKLLNQYCTIPIVFLTSWYSIVIQGRLKKGEKILIHSGCGGVGLATIQISMMIGAEIHVTVGSNEKKQYLIKEFGIDEKRIYSSRSLQFYNDLMVNTDGQGVDMVLNSLSGEYLEKSIQCLSQYGRFIEIGKKDIYSNSSIHLEPFKNNLSFFAVDIAQMTENRRDYLREIMIDQLLPCFKNGSLKPLNQHCFNSPCDLVKAIRFMSSGNHIGKILINWSNLNNDKQFINHHSVVHLPIQSFSNRSTYIFTGFGGLTQTLLKYFSTESDLTNVIIVSKNGLDDNSGSGSGNNEKLKLINQLKESGLNVLVEKCDLSSIKQVYKLFNKIFDNDASGSDSGDFSDIKGIFHFASLINDKRILKHNLESFNYVYNSKATSAWNLHQVSLKYNLNLDHFQTIGSVITILGNIGQSNYTCANRFVEGLTHLRIGMGLKSSCIHLASIPDVGMASNDNVLNDLNSMGFVPFQSLNEMNLGFKKLLSSPNPIVVLGEINVDRFIEATPNFRAKDNFIITSLFNRIDPLLLVNESQDFIINNNINNNGGGGDGSFDDLNQLEDEGQQGFGNGDGYVDDNIDSVSMLSGTSSIFDNDFYTKSIRGMLCDILELKDKDLNNTVSFSDYGLDSLLSSELSNTIQKNFSILIPSLTLVDNSTINSTVELIKNKLKNSTTSSISSSVSKKVSFKKNTQPLIIPTTAPISIIKTQSYIKSEIIESLPISSSTTIKPLVFDNLVYSSSSSNNSNSKNELTSPPPSAKRESVLPIISEDNNSDNDSSMATVIYEISPIAAPYHRYQTDVLKEITQLTPHKEFIDNIYKKSKIRSRYCFNDFSEKSMADINKLDAGERVALFREQTYQTVINAGKTVIERAGIDPMLISHVVGVTSTGIMAPSFDVVLIDKLGLSINTSRTMINFMGCGAAVNSMRAATAYAKLKPGTFVLVVAVEASATCMKFNFDSRSDLLSQAIFTDGCVATLVTCQPKSSLVGKLEIIDDLSYLMPDSRDALNLFIGPTGIDLDLRPELPIAINRHINSAITSWLKKNSLQKSDIEFFATHPGGAKIISAVHEGLGLSPEDLSDSYEVMKRYGNMIGVSTYYVLRRILDKNQTLLQEGSLGYNYGMAMAFSPGASIEAILFKLIK", "length": 2968 }, "evidence": [ { "id": "A0ABI0NT64", "url": "https://omabrowser.org/oma/group/A0ABI0NT64/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "phosphopantetheine binding", "id": "GO:0031177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031177", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ], "pmid": "" }, { "name": "fatty acid synthase activity", "id": "GO:0004312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004312", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ], "pmid": "" }, { "name": "[acyl-carrier-protein] S-acetyltransferase activity", "id": "GO:0004313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004313", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ], "pmid": "" }, { "name": "[acyl-carrier-protein] S-malonyltransferase activity", "id": "GO:0004314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004314", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ], "pmid": "" }, { "name": "3-oxoacyl-[acyl-carrier-protein] synthase activity", "id": "GO:0004315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004315", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ], "pmid": "" }, { "name": "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity", "id": "GO:0004316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004316", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ], "pmid": "" }, { "name": "fatty acyl-[ACP] hydrolase activity", "id": "GO:0016297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016297", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ], "pmid": "" }, { "name": "(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity", "id": "GO:0019171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019171", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ], "pmid": "" }, { "name": "enoyl-[acyl-carrier-protein] reductase (NADPH) activity", "id": "GO:0141148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141148", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT64", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1249, "end_pos": 1251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1493, "end_pos": 1495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1654, "end_pos": 1656, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1731, "end_pos": 1733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1803, "end_pos": 1805, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1818, "end_pos": 1820, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1997, "end_pos": 1999, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2012, "end_pos": 2014, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2053, "end_pos": 2055, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2233, "end_pos": 2235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2346, "end_pos": 2348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2457, "end_pos": 2459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2478, "end_pos": 2480, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13097", "name": "", "equation": "a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "13097", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13097" } ] }, { "id": "17397", "name": "", "equation": "a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "A4IFA7-1", "Q71SP7-1" ], "evidence": [ { "id": "17397", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17397" } ] }, { "id": "22564", "name": "", "equation": "a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "22564", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22564" } ] }, { "id": "22836", "name": "", "equation": "a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q0VCA7-1", "F1MXW5-1" ], "evidence": [ { "id": "22836", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22836" } ] }, { "id": "30123", "name": "", "equation": "tetradecanoyl-[ACP] + H2O = tetradecanoate + holo-[ACP] + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "30123", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30123" } ] }, { "id": "41788", "name": "", "equation": "holo-[ACP] + acetyl-CoA = acetyl-[ACP] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41788", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41788" } ] }, { "id": "41792", "name": "", "equation": "holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BPG0-1", "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41792", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41792" } ] }, { "id": "41800", "name": "", "equation": "acetyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxobutanoyl-[ACP] + holo-[ACP] + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41800", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41800" } ] }, { "id": "41804", "name": "", "equation": "3-oxobutanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxybutanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41804", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41804" } ] }, { "id": "41808", "name": "", "equation": "(3R)-hydroxybutanoyl-[ACP] = (2E)-butenoyl-[ACP] + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41808", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41808" } ] }, { "id": "41812", "name": "", "equation": "(2E)-butenoyl-[ACP] + NADPH + H(+) = butanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "41812", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41812" } ] }, { "id": "41820", "name": "", "equation": "butanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxohexanoyl-[ACP] + holo-[ACP] + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q0VCA7-1", "F1MXW5-1" ], "evidence": [ { "id": "41820", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41820" } ] }, { "id": "41824", "name": "", "equation": "3-oxohexanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyhexanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41824", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41824" } ] }, { "id": "41828", "name": "", "equation": "(3R)-hydroxyhexanoyl-[ACP] = (2E)-hexenoyl-[ACP] + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41828", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41828" } ] }, { "id": "41832", "name": "", "equation": "(2E)-hexenoyl-[ACP] + NADPH + H(+) = hexanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "41832", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41832" } ] }, { "id": "41836", "name": "", "equation": "hexanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxooctanoyl-[ACP] + holo-[ACP] + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q0VCA7-1", "F1MXW5-1" ], "evidence": [ { "id": "41836", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41836" } ] }, { "id": "41840", "name": "", "equation": "3-oxooctanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyoctanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41840", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41840" } ] }, { "id": "41844", "name": "", "equation": "(3R)-hydroxyoctanoyl-[ACP] = (2E)-octenoyl-[ACP] + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41844", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41844" } ] }, { "id": "41848", "name": "", "equation": "(2E)-octenoyl-[ACP] + NADPH + H(+) = octanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "41848", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41848" } ] }, { "id": "41852", "name": "", "equation": "octanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxodecanoyl-[ACP] + holo-[ACP] + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q0VCA7-1", "F1MXW5-1" ], "evidence": [ { "id": "41852", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41852" } ] }, { "id": "41856", "name": "", "equation": "3-oxodecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxydecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41856", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41856" } ] }, { "id": "41860", "name": "", "equation": "(3R)-hydroxydecanoyl-[ACP] = (2E)-decenoyl-[ACP] + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41860", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41860" } ] }, { "id": "41864", "name": "", "equation": "(2E)-decenoyl-[ACP] + NADPH + H(+) = decanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "41864", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41864" } ] }, { "id": "41868", "name": "", "equation": "decanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxododecanoyl-[ACP] + holo-[ACP] + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q0VCA7-1", "F1MXW5-1" ], "evidence": [ { "id": "41868", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41868" } ] }, { "id": "41872", "name": "", "equation": "3-oxododecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxydodecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41872", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41872" } ] }, { "id": "41876", "name": "", "equation": "(3R)-hydroxydodecanoyl-[ACP] = (2E)-dodecenoyl-[ACP] + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41876", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41876" } ] }, { "id": "41880", "name": "", "equation": "(2E)-dodecenoyl-[ACP] + NADPH + H(+) = dodecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "41880", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41880" } ] }, { "id": "41884", "name": "", "equation": "dodecanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxotetradecanoyl-[ACP] + holo-[ACP] + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q0VCA7-1", "F1MXW5-1" ], "evidence": [ { "id": "41884", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41884" } ] }, { "id": "41888", "name": "", "equation": "3-oxotetradecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxytetradecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41888", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41888" } ] }, { "id": "41892", "name": "", "equation": "(3R)-hydroxytetradecanoyl-[ACP] = (2E)-tetradecenoyl-[ACP] + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41892", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41892" } ] }, { "id": "41896", "name": "", "equation": "(2E)-tetradecenoyl-[ACP] + NADPH + H(+) = tetradecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "41896", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41896" } ] }, { "id": "41900", "name": "", "equation": "tetradecanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxohexadecanoyl-[ACP] + holo-[ACP] + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q0VCA7-1", "F1MXW5-1" ], "evidence": [ { "id": "41900", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41900" } ] }, { "id": "41904", "name": "", "equation": "3-oxohexadecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyhexadecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41904", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41904" } ] }, { "id": "41908", "name": "", "equation": "(3R)-hydroxyhexadecanoyl-[ACP] = (2E)-hexadecenoyl-[ACP] + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41908", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41908" } ] }, { "id": "41912", "name": "", "equation": "(2E)-hexadecenoyl-[ACP] + NADPH + H(+) = hexadecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "41912", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41912" } ] }, { "id": "41916", "name": "", "equation": "hexadecanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxooctadecanoyl-[ACP] + holo-[ACP] + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41916", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41916" } ] }, { "id": "41920", "name": "", "equation": "3-oxooctadecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyoctadecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41920", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41920" } ] }, { "id": "41924", "name": "", "equation": "(3R)-hydroxyoctadecanoyl-[ACP] = (2E)-octadecenoyl-[ACP] + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41924", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41924" } ] }, { "id": "41928", "name": "", "equation": "(2E)-octadecenoyl-[ACP] + NADPH + H(+) = octadecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41928", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41928" } ] }, { "id": "41932", "name": "", "equation": "hexadecanoyl-[ACP] + H2O = hexadecanoate + holo-[ACP] + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1" ], "evidence": [ { "id": "41932", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41932" } ] }, { "id": "R-BTA-163756", "name": "Formation of fatty acid synthase (FAS) dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1" ], "evidence": [ { "id": "R-BTA-163756", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163756" } ] }, { "id": "R-BTA-199202", "name": "Phosphopantetheine conjugation of the ACP domain of FAS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-BTA-199233" ], "output_participant_list": [ "R-BTA-54659" ], "enzyme_list": [ "A0A3Q1LL63-1", "A0ABI0NT64-1" ], "evidence": [ { "id": "R-BTA-199202", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-199202" } ] }, { "id": "R-BTA-75872", "name": "Conversion of malonyl-CoA and acetyl-CoA to palmitate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-29508", "R-ALL-76183" ], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1" ], "evidence": [ { "id": "R-BTA-75872", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75872" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-29508", "participant_name": "Mal-CoA [cytosol]", "crossref": [ { "id": "57384", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551112", "database": "ZINC", "url": "" }, { "id": "C00083", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-76183", "participant_name": "Ac-CoA [cytosol]", "crossref": [ { "id": "57288", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551095", "database": "ZINC", "url": "" }, { "id": "C00024", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-BTA-199233", "participant_name": "FASN [cytosol]", "crossref": [ { "id": "F1N647", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000015980", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000021260", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000021260", "database": "ENSEMBL", "url": "" }, { "id": "28871", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-54659", "participant_name": "phospho-FASN [cytosol]", "crossref": [ { "id": "ENSBTAG00000015980", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000021260", "database": "ENSEMBL", "url": "" }, { "id": "28871", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000021260", "database": "ENSEMBL", "url": "" }, { "id": "F1N647", "database": "UniProt", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LL63", "gene_name": "AASDHPPT", "activity": [ { "ec_number": "2.7.8.7", "activity": "apo-[ACP] + CoA = holo-[ACP] + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "A0A3Q1LL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL63" } ] }, { "ec_number": "2.7.8.7", "activity": "", "evidence": [ { "id": "A0A3Q1LL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL63" } ] } ] }, { "uniprot_ac": "A0ABI0NT64", "gene_name": "FASN", "activity": [ { "ec_number": "1.1.1.100", "activity": "a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+).", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "1.3.1.39", "activity": "a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+).", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.38", "activity": "holo-[ACP] + acetyl-CoA = acetyl-[ACP] + CoA.", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.39", "activity": "holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA.", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.41", "activity": "a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2.", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.85", "activity": "acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H(+) = a long-chain fatty acid + (n+1) CoA + n CO2 + 2n NADP(+).", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "3.1.2.14", "activity": "hexadecanoyl-[ACP] + H2O = hexadecanoate + holo-[ACP] + H(+).", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "4.2.1.59", "activity": "a (3R)-hydroxyacyl-[ACP] = a 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(PI3K)" }, { "id": "R-BTA-9927354", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9927354", "resource": "Reactome", "description": "Co-stimulation by ICOS" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "phosphatidylinositol-3-phosphate biosynthetic process", "id": "GO:0036092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036092", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ], "pmid": "" }, { "name": "regulation of locomotion", "id": "GO:0040012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040012", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ], "pmid": "" }, { "name": "phosphatidylinositol-mediated signaling", "id": "GO:0048015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048015", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0043491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043491", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-3-kinase activity", "id": "GO:0016303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016303", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity", "id": "GO:0046934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046934", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-4-phosphate 3-kinase activity", "id": "GO:0035005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035005", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase complex, class IB", "id": "GO:0005944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005944", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase complex, class IA", "id": "GO:0005943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005943", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 825, "end_pos": 827, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12709", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9THJ4-1", "F1MTL5-1", "P32871-1", "E1BE68-1", "E1BE66-1", "A0ABI0NMT8-1" ], "evidence": [ { "id": "12709", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12709" } ] }, { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "18373", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9THJ4-1", "E1BE68-1", "A0ABI0NMT8-1" ], "evidence": [ { "id": "18373", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18373" } ] }, { "id": "21292", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MYM3-1", "P32871-1", "A0ABI0NMT8-1", "E1BE66-1", "E1BE68-1" ], "evidence": [ { "id": "21292", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21292" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LU59", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] } ] }, { "uniprot_ac": "A0A3Q1LW88", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] } ] }, { "uniprot_ac": "A0A3Q1LWT7", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] } ] }, { "uniprot_ac": "A0A3Q1LYH3", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LYH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LYH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYH3" } ] } ] }, { "uniprot_ac": "A0A3Q1M1Z0", "gene_name": "ULK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Z0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M1Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Z0" } ] } ] }, { "uniprot_ac": "A0A3Q1M2U5", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2U5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2U5" } ] } ] }, { "uniprot_ac": "A0A3Q1M334", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M334" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M334" } ] } ] }, { "uniprot_ac": "A0A3Q1M4N6", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4N6" } ] } ] }, { "uniprot_ac": "A0A3Q1M4X3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4X3" } ] } ] }, { "uniprot_ac": "A0A3Q1M5T5", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M5T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5T5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1M5T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5T5" } ] } ] }, { "uniprot_ac": "A0A3Q1M614", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M614" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M614" } ] } ] }, { "uniprot_ac": "A0A3Q1M6N5", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M6N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6N5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M6N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6N5" } ] } ] }, { "uniprot_ac": "A0A3Q1M9F0", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M9F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M9F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9F0" } ] } ] }, { "uniprot_ac": "A0A3Q1M9L7", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M9L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9L7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M9L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9L7" } ] } ] }, { "uniprot_ac": "A0A3Q1MA37", "gene_name": "CDC42BPG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MA37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MA37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA37" } ] } ] }, { "uniprot_ac": "A0A3Q1MD82", "gene_name": "CDK16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD82" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1MD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD82" } ] } ] }, { "uniprot_ac": "A0A3Q1MEZ6", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MHH5", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] } ] }, { "uniprot_ac": "A0A3Q1MHL3", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] } ] }, { "uniprot_ac": "A0A3Q1MHM3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] } ] }, { "uniprot_ac": "A0A3Q1MI36", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] } ] }, { "uniprot_ac": "A0A3Q1MKC7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9THJ4", "gene_name": "PIK3C2G", "activity": [ { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9THJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THJ4" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9THJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THJ4" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0AAA9THJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THJ4" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0AAA9THJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THJ4" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BE66", "gene_name": "PIK3CD", "activity": [ { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1BE66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE66" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1BE66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE66" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1BE66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE66" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1BE66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE66" } ] } ] }, { "uniprot_ac": "E1BE68", "gene_name": "PIK3C2A", "activity": [ { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1BE68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE68" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1BE68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE68" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1BE68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE68" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1BE68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE68" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1BE68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE68" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1BE68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE68" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MTL5", "gene_name": "PIK3C3", "activity": [ { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "F1MTL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTL5" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "F1MTL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTL5" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF02376", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024840234", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840234", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7Z3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT67", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT67-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGGPGHEPELLASPSPHHAGRGAAGSLRGPPPPPPPPPPPTAHQELGTAAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHHQQRLSGNVSGSFTLLRDERGLPTMNNLYSPYKEMPGMGQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGPDKMLSPNFDAHHTAMLTRGDQHLSRGLGTPPAAMMSHLNGLHHPGHAQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPSKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLSAGGASSTSGTCTKA", "length": 514, "header": "tr|A0ABI0NT67-1|A0ABI0NT67_BOVIN Isoform 1 of One cut domain family member OS=Bos taurus OX=9913 GN=ONECUT2 PE=3 SV=1 CANONICAL=A0ABI0NT67-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M7Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT67/entry#A0A3Q1M7Z3-1", "sequence": { "sequence": "MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGGPGHEPELLASPSPHHAGRGAAGSLRGPPPPPPPPPPPTAHQELGTAAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHHQQRLSGNVSGSFTLLRDERGLPTMNNLYSPYKEMPGMGQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGPDKMLSPNFDAHHTAMLTRGDQHLSRGLGTPPAAMMSHLNGLHHPGHAQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAGASPAGSDGVWLQLHPRPRPVDAPRSGPLEGVQRSRGAELPVGACKRKEQEPSKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLSAGGASSTSGTCTKA", "length": 557, "header": "tr|A0A3Q1M7Z3-1|A0ABI0NT67_BOVIN Computationally mapped isoform of One cut domain family member OS=Bos taurus OX=9913 GN=ONECUT2 PE=3 SV=1 CANONICAL=A0ABI0NT67-1" }, "locus": { "chromosome": "24", "start_pos": 56728114, "end_pos": 56682519, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080397.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080397.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064513.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064513.1" } ] } }, { "isoform_ac": "A0ABI0NT67-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT67/entry#A0ABI0NT67-1", "sequence": { "sequence": "MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGGPGHEPELLASPSPHHAGRGAAGSLRGPPPPPPPPPPPTAHQELGTAAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHHQQRLSGNVSGSFTLLRDERGLPTMNNLYSPYKEMPGMGQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGPDKMLSPNFDAHHTAMLTRGDQHLSRGLGTPPAAMMSHLNGLHHPGHAQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPSKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLSAGGASSTSGTCTKA", "length": 514, "header": "tr|A0ABI0NT67-1|A0ABI0NT67_BOVIN Isoform 1 of One cut domain family member OS=Bos taurus OX=9913 GN=ONECUT2 PE=3 SV=1 CANONICAL=A0ABI0NT67-1" }, "locus": { "chromosome": "24", "start_pos": 56728114, "end_pos": 56682519, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142466.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142466.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107620.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107620.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KA21-1", "protein_name": "One cut homeobox 2", "gene_name": "Onecut2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPVGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGSDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHHHQRLSGNVSGSFTLMRDERGLPSMNNLYSPYKEMPSMSQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPGHTQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAGQVYQSPRKAGPSSQPMNLPSLSTVKLGYTAKTTPPDQVSEVRIVPK", "length": 457 }, "evidence": [ { "id": "A0ABI0NT67", "url": "https://omabrowser.org/oma/group/A0ABI0NT67/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95948-1", "protein_name": "One cut domain family member 2", "gene_name": "ONECUT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHQRLSGNVSGSFTLMRDERGLPAMNNLYSPYKEMPGMSQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPGHTQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLSTGGSSSTSSTCTKA", "length": 504 }, "evidence": [ { "id": "A0ABI0NT67", "url": "https://omabrowser.org/oma/group/A0ABI0NT67/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6XBJ3-1", "protein_name": "One cut domain family member 2", "gene_name": "Onecut2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPVGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGSDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHHHQRLSGNVSGSFTLMRDERGLPSMNNLYSPYKEMPSMSQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPGHTQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLGTGGSSSTSSTCTKA", "length": 505 }, "evidence": [ { "id": "A0ABI0NT67", "url": "https://omabrowser.org/oma/group/A0ABI0NT67/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT67", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT67" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT67", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT67" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT67", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT67" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT67", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT67" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT67", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT67" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT67", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT67" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT67", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT67" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT67", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NT67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT67" }, { "id": "PS51042", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51042" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUT", "eco_id": "ECO_0000259", "start_pos": 334, "end_pos": 420, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NT67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT67" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 434, "end_pos": 494, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 433, "end_pos": 435 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQ55-1", "uniprot_ac": "A0ABI0NQ55", "uniprot_id": "A0ABI0NQ55_BOVIN", "mass": { "chemical_mass": 118405.0, "monoisotopic_mass": 118405.0 }, "refseq": { "ac": "XP_003585731", "name": "histone-lysine N-methyltransferase MECOM isoform X8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003585731" }, "gene_names": [ { "name": "MECOM", "type": "recommended", "evidence": [ { "id": "A0ABI0NQ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ55" } ] }, { "name": "MECOM", "type": "synonym", "evidence": [ { "id": "XP_003585731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003585731" } ] } ], "protein_names": [ { "name": "MDS1 and EVI1 complex locus", "type": "synonym", "evidence": [ { "id": "A0ABI0NQ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ55/entry#names_and_taxonomy" } ] }, { "name": "histone-lysine N-methyltransferase MECOM isoform X8", "type": "synonym", "evidence": [ { "id": "XP_003585731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003585731" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ55", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ55" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MECOM", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ55", "locus": { "chromosome": "1", "start_pos": 98348504, "end_pos": 97692611, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005871", "url": "https://www.ensembl.org/id/ENSBTAG00000005871" } ] } } ], "crossref": [ { "id": "ENSBTAG00000005871", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005871", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532209", "url": "https://www.ncbi.nlm.nih.gov/gene/532209", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044411", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044411", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532209", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532209", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LI16", "url": "https://www.orthodb.org/?gene=A0A3Q1LI16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LSV2", "url": "https://www.orthodb.org/?gene=A0A3Q1LSV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MGQ4", "url": "https://www.orthodb.org/?gene=A0A3Q1MGQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MWB8", "url": "https://www.orthodb.org/?gene=A0A3Q1MWB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BMZ2", "url": "https://www.orthodb.org/?gene=E1BMZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF66", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF66", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21549", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21549", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3214841", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214841", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8943724", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8943724", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003585731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003585731", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LI16", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LI16-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGQ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MWB8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MWB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLE2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLE2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ55", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ55-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMZ2", "url": "https://www.uniprot.org/uniprotkb/E1BMZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMZ2-1", "url": "https://www.uniprot.org/uniprotkb/E1BMZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSEDYSHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEDDFQQKLETENDLREIHAIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKQVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKHPPVGDNKPVELQPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDIESDKEKFKENGKMFKDKVSPLQNLASIHNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPLKMEPQSPSEVKKLQKGSSESPFDLTTKRKDEKPLTPVPAKPSATPAASQDQPLDLSMGSRSRASGTKLTEPRKNHVFGEKKGGNIEPRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQFQLPDQRTWMSAIENMAEKLENFSALKPEASELLQSVPSMFNFRAPPNALPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNAEERMNGSHFKDEKALVTNQNSDLLDDEEVEDEVLLDEEDEDNDITGKMGKEPGTSNLHEGNPEDDYEDTSTLEMSCKASPMRYKEEEYKTGLSALDHIRHFTDSLKMRKMEDNQYTEAEVSSFSASHVPEELKQPLHRKSKSQAYAMMLSLSDKESLHSSSHSSSNVWHSMARAAAESSAIQSISHV", "length": 1052, "header": "tr|A0ABI0NQ55-1|A0ABI0NQ55_BOVIN Isoform 1 of MDS1 and EVI1 complex locus OS=Bos taurus OX=9913 GN=MECOM PE=4 SV=1 CANONICAL=A0ABI0NQ55-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LI16-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ55/entry#A0A3Q1LI16-1", "sequence": { "sequence": "MPDADGVAGALSLSIQEPCSPATSSEAFTPKEGSPYKAPIYIPDDIPIPAEFELRESNMPGAGLGIWSKRKIEAGEKFGPYVGEQRSNLKDPSYGWEILDEFCNVKFCIDASQPDVGSWLKYIRFAGCYDQHNLVACQINDQIFYRVVADIAPGEELLLFMKSEDYSHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEDDFQQKLETENDLREIHAIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKQVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKHPPVGDNKPVELQPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDIESDKEKFKENGKMFKDKVSPLQNLASIHNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPLKMEPQSPSEVKKLQKGSSESPFDLTTKRKDEKPLTPVPAKPSATPAASQDQPLDLSMGSRSRASGTKLTEPRKNHVFGEKKGGNIEPRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQFQLPDQRTWMSAIENMAEKLENFSALKPEASELLQSVPSMFNFRAPPNALPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNAEERMNGSHFKDEKALVTNQNSDLLDDEEVEDEVLLDEEDEDNDITGKMGKEPGTSNLHEGNPEDDYEDTSTLEMSCKASPMRYKEEEYKTGLSALDHIRHFTDSLKMRKMEDNQYTEAEVSSFSASHVPEELKQPLHRKSKSQAYAMMLSLSDKESLHSSSHSSSNVWHSMARAAAESSAIQSISHV", "length": 1212, "header": "tr|A0A3Q1LI16-1|A0ABI0NQ55_BOVIN Computationally mapped isoform of MDS1 and EVI1 complex locus OS=Bos taurus OX=9913 GN=MECOM PE=4 SV=2 CANONICAL=A0ABI0NQ55-1" }, "locus": { "chromosome": "1", "start_pos": 98347500, "end_pos": 98022988, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078562.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078562.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058544.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058544.2" } ] } }, { "isoform_ac": "A0A3Q1LSV2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ55/entry#A0A3Q1LSV2-1", "sequence": { "sequence": "MKSEDYSHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEDDFQQKLETENDLREIHAIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKHPPVGDNKPVELQPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDIESDKEKFKENGKMFKDKVSPLQNLASIHNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPLKMEPQSPSEVKKLQKGSSESPFDLTTKRKDEKPLTPVPAKPSATPAASQDQPLDLSMGSRSRASGTKLTEPRKNHVFGEKKGGNIEPRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQMSAIENMAEKLENFSALKPEASELLQSVPSMFNFRAPPNALPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNAEERMNGSHFKDEKALVTNQNSDLLDDEEVEDEVLLDEEDEDNDITGKMGKEPGTSNLHEGNPEDDYEDTSTLEMSCKASPMRYKEEEYKTGLSALDHIRHFTDSLKMRKMEDNQYTEAEVSSFSASHVPEELKQPLHRKSKSQAYAMMLSLSDKESLHSSSHSSSNVWHSMARAAAESSAIQSISHV", "length": 1042, "header": "tr|A0A3Q1LSV2-1|A0ABI0NQ55_BOVIN Computationally mapped isoform of MDS1 and EVI1 complex locus OS=Bos taurus OX=9913 GN=MECOM PE=4 SV=3 CANONICAL=A0ABI0NQ55-1" }, "locus": { "chromosome": "1", "start_pos": 98347500, "end_pos": 98295334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070527.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070527.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058164.3", "url": "https://www.ensembl.org/id/ENSBTAP00000058164.3" } ] } }, { "isoform_ac": "A0A3Q1MGQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ55/entry#A0A3Q1MGQ4-1", "sequence": { "sequence": "MRSKGRARKLATNNECVYGSYPEIPLEEMPDADGVAGALSLSIQEPCSPATSSEAFTPKEGSPYKAPIYIPDDIPIPAEFELRESNMPGAGLGIWSKRKIEAGEKFGPYVGEQRSNLKDPSYGWEILDEFCNVKFCIDASQPDVGSWLKYIRFAGCYDQHNLVACQINDQIFYRVVADIAPGEELLLFMKSEDYSHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEDDFQQKLETENDLREIHAIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKQVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKHPPVGDNKPVELQPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDIESDKEKFKENGKMFKDKVSPLQNLASIHNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPLKMEPQSPSEVKKLQKGSSESPFDLTTKRKDEKPLTPVPAKPSATPAASQDQPLDLSMGSRSRASGTKLTEPRKNHVFGEKKGGNIEPRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQMSAIENMAEKLENFSALKPEASELLQSVPSMFNFRAPPNALPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNAEERMNGSHFKDEKALVTNQNSDLLDDEEVEDEVLLDEEDEDNDITGKMGKEPGTSNLHEGNPEDDYEDTSTLEMSCKASPMRYKEEEYKTGLSALDHIRHFTDSLKMRKMEDNQYTEAEVSSFSASHVPEELKQPLHRKSKSQAYAMMLSLSDKESLHSSSHSSSNVWHSMARAAAESSAIQSISHV", "length": 1231, "header": "tr|A0A3Q1MGQ4-1|A0ABI0NQ55_BOVIN Computationally mapped isoform of MDS1 and EVI1 complex locus OS=Bos taurus OX=9913 GN=MECOM PE=4 SV=3 CANONICAL=A0ABI0NQ55-1" }, "locus": { "chromosome": "1", "start_pos": 98347500, "end_pos": 97692810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078481.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078481.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069770.3", "url": "https://www.ensembl.org/id/ENSBTAP00000069770.3" } ] } }, { "isoform_ac": "A0A3Q1MWB8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ55/entry#A0A3Q1MWB8-1", "sequence": { "sequence": "VILDEFCNVKFCIDASQPDVGSWLKYIRFAGCYDQHNLVACQINDQIFYRVVADIAPGEELLLFMKSEDYSHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEDDFQQKLETENDLREIHAIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKQVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKHPPVGDNKPVELQPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDIESDKEKFKENGKMFKDKVSPLQNLASIHNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPLKMEPQSPSEVKKLQKGSSESPFDLTTKRKDEKPLTPVPAKPSATPAASQDQPLDLSMGSRSRASGTKLTEPRKNHVFGEKKGGNIEPRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQFQLPDQRTWMSAIENMAEKLENFSALKPEASELLQSVPSMFNFRAPPNALPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNAEERMNGSHFKDEKALVTNQNSDLLDDEEVEDEVLLDEEDEDNDITGKMGKEPGTSNLHEGNPEDDYEDTSTLEMSCKASPMRYKEEEYKTGLSALDHIRHFTDSLKMRKMEDNQYTEAEVSSFSASHVPEELKQPLHRKSKSQAYAMMLSLSDKESLHSSSHSSSNVWHSMARAAAESSAIQSISHV", "length": 1116, "header": "tr|A0A3Q1MWB8-1|A0ABI0NQ55_BOVIN Computationally mapped isoform of MDS1 and EVI1 complex locus OS=Bos taurus OX=9913 GN=MECOM PE=4 SV=2 CANONICAL=A0ABI0NQ55-1" }, "locus": { "chromosome": "1", "start_pos": 98347500, "end_pos": 98282033, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079180.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079180.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059674.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059674.2" } ] } }, { "isoform_ac": "A0ABI0NLE2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ55/entry#A0ABI0NLE2-1", "sequence": { "sequence": "MPDADGVAGALSLSIQEPCSPATSSEAFTPKEGSPYKAPIYIPDDIPIPAEFELRESNMPGAGLGIWSKRKIEAGEKFGPYVGEQRSNLKDPSYGWEILDEFCNVKFCIDASQPDVGSWLKYIRFAGCYDQHNLVACQINDQIFYRVVADIAPGEELLLFMKSEDYSHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEDDFQQKLETENDLREIHAIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKHPPVGDNKPVELQPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDIESDKEKFKENGKMFKDKVSPLQNLASIHNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPLKMEPQSPSEVKKLQKGSSESPFDLTTKRKDEKPLTPVPAKPSATPAASQDQPLDLSMGSRSRASGTKLTEPRKNHVFGEKKGGNIEPRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQMSAIENMAEKLENFSALKPEASELLQSVPSMFNFRAPPNALPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNAEERMNGSHFKDEKALVTNQNSDLLDDEEVEDEVLLDEEDEDNDITGKMGKEPGTSNLHEGNPEDDYEDTSTLEMSCKASPMRYKEEEYKTGLSALDHIRHFTDSLKMRKMEDNQYTEAEVSSFSASHVPEELKQPLHRKSKSQAYAMMLSLSDKESLHSSSHSSSNVWHSMARAAAESSAIQSISHV", "length": 1202, "header": "tr|A0ABI0NLE2-1|A0ABI0NQ55_BOVIN Computationally mapped isoform of MDS1 and EVI1 complex locus OS=Bos taurus OX=9913 GN=MECOM PE=4 SV=1 CANONICAL=A0ABI0NQ55-1" }, "locus": { "chromosome": "1", "start_pos": 98347500, "end_pos": 98022988, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146156.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146156.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105562.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105562.1" } ] } }, { "isoform_ac": "A0ABI0NQ55-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ55/entry#A0ABI0NQ55-1", "sequence": { "sequence": 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"", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 577, "start_aa": "Thr", "end_pos": 577, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr577", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:532209", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532209", "resource": "KEGG Pathway" }, { "id": "R-BTA-3214841", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214841", "resource": "Reactome", "description": "PKMTs methylate 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"url": "https://www.ncbi.nlm.nih.gov/protein/XP_010801288" }, "gene_names": [ { "name": "PGLYRP3", "type": "recommended", "evidence": [ { "id": "A0ABI0NNK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6" } ] }, { "name": "PGLYRP3", "type": "synonym", "evidence": [ { "id": "XP_010801288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010801288" } ] } ], "protein_names": [ { "name": "Peptidoglycan recognition protein 1", "type": "recommended", "evidence": [ { "id": "A0ABI0NNK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6/entry#names_and_taxonomy" } ] }, { "name": "peptidoglycan recognition protein 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_010801288", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010801288" } ] } ], "function": [ { "annotation": "Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Also binds to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.", "evidence": [ { "database": "UniProtKB", "id": "E1BJ76", "url": "https://www.uniprot.org/uniprotkb/E1BJ76#function" }, { "database": "UniProtKB", "id": "ARBA00053301", "url": "https://www.uniprot.org/uniprotkb/ARBA00053301#function" }, { "database": "UniProtKB", "id": "A0AAA9ST59", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST59#function" }, { "database": "UniProtKB", "id": "A0ABI0NZ76", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ76#function" }, { "database": "UniProtKB", "id": "A0ABI0NNK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PGLYRP3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6", "locus": { "chromosome": "3", "start_pos": 17170012, "end_pos": 17147330, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021443", "url": "https://www.ensembl.org/id/ENSBTAG00000021443" } ] } } ], "crossref": [ { "id": "ENSBTAG00000021443", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021443", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06583", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06583", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532575", "url": "https://www.ncbi.nlm.nih.gov/gene/532575", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532575", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532575", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M1U5", "url": "https://www.orthodb.org/?gene=A0A3Q1M1U5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BJ76", "url": "https://www.orthodb.org/?gene=E1BJ76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11022", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11022", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11022:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11022:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01510", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01510", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6803157", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6803157", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010801288", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010801288", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1U5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1U5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9ST59", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9ST59-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNK6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ76", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ76-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ76", "url": "https://www.uniprot.org/uniprotkb/E1BJ76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ76-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRMLLWFLVLSALDLAAWGVPTIVSRKEWGARSLTCRAQLTRPVAYVITDQITGMECEEQNACSQKLRGLQSRSVYTKGWCDVAYNFLVGNDGRVYEGVGWNIQGMHTQGYNNISLGLAFFGNNLGSSPSPTALSAAEDLIFYAIKNGHLSPRYIQPLLLKAESCLVPHQPLMPRKACPNIITRSAWEARQTHCPTMSLPAKYVVIIHTAGATCNVSMDCRIRVRDIQSYHIDAKDFCDIGYHFLVGQDGGVYEGVGWHTEGSHTYGYNDIGLGIAFIGNFVEKPPNAAALEAAQSLIHCSVVKGYLVPNYLLVGHSDVTDILSPGRALYNIIKTWPHFRQ", "length": 341, "header": "tr|A0ABI0NNK6-1|A0ABI0NNK6_BOVIN Isoform 1 of Peptidoglycan recognition protein 1 OS=Bos taurus OX=9913 GN=PGLYRP3 PE=3 SV=1 CANONICAL=A0ABI0NNK6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M1U5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6/entry#A0A3Q1M1U5-1", "sequence": { "sequence": "MRMLLWFLVLSALDLAAWGDSLELSWNETQARGLSQELLDLFVGISQLIHTGHNGVPTIVSRKEWGARSLTCRAQLTRPVAYVITDQITGMECEEQNACSQKLRGLQSRSVYTKGWCDVAYNFLVGNDGRVYEGVGWNIQGMHTQGYNNISLGLAFFGNNLGSSPSPTALSAAEDLIFYAIKNGHLSPRYIQPLLLKAESCLVPHQPLMPRKACPNIITRSAWEARQTHCPTMSLPAKYVVIIHTAGATCNVSMDCRIRVRDIQSYHIDAKDFCDIGYHFLVGQDGGVYEGVGWHTEGSHTYGYNDIGLGIAFIGNFVDYKGCESGDHAHCVHVCLLLVHSSFIASMLFLLAAR", "length": 354, "header": "tr|A0A3Q1M1U5-1|A0ABI0NNK6_BOVIN Computationally mapped isoform of Peptidoglycan recognition protein 1 OS=Bos taurus OX=9913 GN=PGLYRP3 PE=3 SV=2 CANONICAL=A0ABI0NNK6-1" }, "locus": { "chromosome": "3", "start_pos": 17169051, "end_pos": 17150108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078335.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078335.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063937.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063937.2" } ] } }, { "isoform_ac": "A0AAA9ST59-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6/entry#A0AAA9ST59-1", "sequence": { "sequence": "MRMLLWFLVLSALDLAAWGDSLELSWNETQARGLSQELLDLFVGISQLIHTGHNGVPTIVSRKEWGARSLTCRAQLTRPVAYVITDQITGMECEEQNACSQKLRGLQSRSVYTKGWCDVAYNFLVGNDGRVYEGVGWNIQGMHTQGYNNISLGLAFFGNNLGSSPSPTALSAAEDLIFYAIKNGHLSPRYIQPLLLKAESCLVPHQPLMPRKACPNIITRSAWEARQTHCPTMSLPAKYVVIIHTAGATCNVSMDCRIRVRDIQSYHIDAKDFCDIGYHFLVGQDGGVYEGVGWHTEGSHTYGYNDIGLGIAFIGNFVEKPPNAAALEAAQSLIHCSVVKGLQGLREWRSCSLRSCLSAPGA", "length": 362, "header": "tr|A0AAA9ST59-1|A0ABI0NNK6_BOVIN Computationally mapped isoform of Peptidoglycan recognition protein 1 OS=Bos taurus OX=9913 GN=PGLYRP3 PE=3 SV=1 CANONICAL=A0ABI0NNK6-1" }, "locus": { "chromosome": "3", "start_pos": 17169008, "end_pos": 17150108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108458.2", "url": "https://www.ensembl.org/id/ENSBTAT00000108458.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089605.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089605.1" } ] } }, { "isoform_ac": "A0ABI0NNK6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6/entry#A0ABI0NNK6-1", "sequence": { "sequence": "MRMLLWFLVLSALDLAAWGVPTIVSRKEWGARSLTCRAQLTRPVAYVITDQITGMECEEQNACSQKLRGLQSRSVYTKGWCDVAYNFLVGNDGRVYEGVGWNIQGMHTQGYNNISLGLAFFGNNLGSSPSPTALSAAEDLIFYAIKNGHLSPRYIQPLLLKAESCLVPHQPLMPRKACPNIITRSAWEARQTHCPTMSLPAKYVVIIHTAGATCNVSMDCRIRVRDIQSYHIDAKDFCDIGYHFLVGQDGGVYEGVGWHTEGSHTYGYNDIGLGIAFIGNFVEKPPNAAALEAAQSLIHCSVVKGYLVPNYLLVGHSDVTDILSPGRALYNIIKTWPHFRQ", "length": 341, "header": "tr|A0ABI0NNK6-1|A0ABI0NNK6_BOVIN Isoform 1 of Peptidoglycan recognition protein 1 OS=Bos taurus OX=9913 GN=PGLYRP3 PE=3 SV=1 CANONICAL=A0ABI0NNK6-1" }, "locus": { "chromosome": "3", "start_pos": 17162770, "end_pos": 17150108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143395.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143395.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107394.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107394.1" } ] } }, { "isoform_ac": "A0ABI0NZ76-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6/entry#A0ABI0NZ76-1", "sequence": { "sequence": "MRMLLWFLVLSALDLAAWGDSLELSWNETQARGLSQELLDLFVGISQLIHTGHNGVPTIVSRKEWGARSLTCRAQLTRPVAYVITDQITGMECEEQNACSQKLRGLQSRSVYTKGWCDVAYNFLVGNDGRVYEGVGWNIQGMHTQGYNNISLGLAFFGNNLGSSPSPTALSAAEDLIFYAIKNGHLSPRYIQPLLLKAESCLVPHQPLMPRKACPNIITRSAWEARQTHCPTMSLPAKYVVIIHTAGATCNVSMDCRIRVRDIQSYHIDAKDFCDIGYHFLVGQDGGVYEGVGWHTEGSHTYGYNDIGLGIAFIGNFVEKPPNAAALEAAQSLIHCSVVKGYLVPNYLLVGHSDVTDILSPGRALYNIIKTWPHFRQ", "length": 377, "header": "tr|A0ABI0NZ76-1|A0ABI0NZ76_BOVIN Computationally mapped isoform of Peptidoglycan recognition protein 1 OS=Bos taurus OX=9913 GN=PGLYRP3 PE=3 SV=1 CANONICAL=A0ABI0NNK6-1" }, "locus": { "chromosome": "3", "start_pos": 17162770, "end_pos": 17150108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144799.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144799.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106902.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106902.1" } ] } }, { "isoform_ac": "E1BJ76-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6/entry#E1BJ76-1", "sequence": { "sequence": "MFVMIVCVCVCVCALSRFSCALTLCCPMDCSLPGSSVHGILQARILEGVAVPSSRDLPDPGIEPEAPGLQGNSLFTEPSGKPICGDSLELSWNETQARGLSQELLDLFVGISQLIHTGHNGVPTIVSRKEWGARSLTCRAQLTRPVAYVITDQITGMECEEQNACSQKLRGLQSRSVYTKGWCDVAYNFLVGNDGRVYEGVGWNIQGMHTQGYNNISLGLAFFGNNLGSSPSPTALSAAEDLIFYAIKNGHLSPRYIQPLLLKAESCLVPHQPLMPRKACPNIITRSAWEARQTHCPTMSLPAKYVVIIHTAGATCNVSMDCRIRVRDIQSYHIDAKDFCDIGYHFLVGQDGGVYEGVGWHTEGSHTYGYNDIGLGIAFIGNFVEKPPNAAALEAAQSLIHCSVVKGYLVPNYLLVGHSDVTDILSPGRALYNIIKTWPHFRQ", "length": 443, "header": "tr|E1BJ76-1|A0ABI0NNK6_BOVIN Computationally mapped isoform of Peptidoglycan recognition protein 1 OS=Bos taurus OX=9913 GN=PGLYRP3 PE=3 SV=2 CANONICAL=A0ABI0NNK6-1" }, "locus": { "chromosome": "3", "start_pos": 17162770, "end_pos": 17150819, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028587.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028587.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028587.5", "url": "https://www.ensembl.org/id/ENSBTAP00000028587.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:532575", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532575", "resource": "KEGG Pathway" }, { "id": "R-BTA-6803157", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6803157", "resource": "Reactome", "description": "Antimicrobial peptides" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "N-acetylmuramoyl-L-alanine amidase activity", "id": "GO:0008745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008745", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6" } ], "pmid": "" }, { "name": "peptidoglycan binding", "id": "GO:0042834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042834", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6" } ], "pmid": "" }, { "name": "peptidoglycan immune receptor activity", "id": "GO:0016019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016019", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "innate immune 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"defense response to fungus", "id": "GO:0050832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050832", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNK6" } ], "pmid": "" }, { "name": "antimicrobial humoral immune response mediated by antimicrobial peptide", "id": "GO:0061844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061844", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNK6", "url": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NNV1-1", "uniprot_ac": "A0ABI0NNV1", "uniprot_id": "A0ABI0NNV1_BOVIN", "mass": { "chemical_mass": 121529.0, "monoisotopic_mass": 121529.0 }, "refseq": { "ac": "XP_015326555", "name": "brother of CDO isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326555" }, "gene_names": [ { "name": "BOC", "type": "recommended", "evidence": [ { "id": "A0ABI0NNV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1" } ] }, { "name": "BOC", "type": "synonym", "evidence": [ { "id": "XP_015326555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326555" } ] } ], "protein_names": [ { "name": "Brother of CDO", "type": "recommended", "evidence": [ { "id": "A0ABI0NNV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1/entry#names_and_taxonomy" } ] }, { "name": "brother of CDO isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015326555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326555" } ] } ], "function": [ { "annotation": "Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNV1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1#function" }, { "database": "UniProtKB", "id": "ARBA00057094", "url": "https://www.uniprot.org/uniprotkb/ARBA00057094#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNV1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BOC", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1", "locus": { "chromosome": "1", "start_pos": 58023212, "end_pos": 57951984, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013909", "url": "https://www.ensembl.org/id/ENSBTAG00000013909" } ] } } ], "crossref": [ { "id": "ENSBTAG00000013909", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013909", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512018", "url": "https://www.ncbi.nlm.nih.gov/gene/512018", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512018", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512018", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KQTSDMC", "url": "https://omabrowser.org/oma/group/KQTSDMC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BB93", "url": "https://www.orthodb.org/?gene=E1BB93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-525793", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-525793", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5635838", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5635838", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015326555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326555", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NNV1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNV1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BB93", "url": "https://www.uniprot.org/uniprotkb/E1BB93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BB93-1", "url": "https://www.uniprot.org/uniprotkb/E1BB93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRGMMAMQRGKQPEVTLACLLLAAAGCFADLNEVPQVTVQPSSTVQKLGGTVILGCVVEPPWMNTTWRLNGRELNGSDDSLGILITRGTLVVTALNNHTVGRYQCVARMPAGAVASVPATVTLANLQDFKLDVQHVIEVDEGNTAVIACHLPESHPKAQVRYSVKQEWLEASRDNYLIMPSGNLQIVNASQEDEGMYKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPPEAQTIVVTKGQSLILECVASGIPPPRVTWAKDGSSVASYNKTRFLLSNLLIDTTNEEDSGTYRCMADNGVGEPGAAVILYNVQVFEPPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLTSSQRLRLSHRALRVVSMGPEDEGVYQCMAENEVGSAHAVVQLKTARPGTTLRPWWDAQSATVTPPVPPSRPGGPDQMPKGHPGLLRPQASEQPASPQCPGDQGPVAPAEAPIILSSPRTSKTDSYELVWRPRHEGSSRAPVLYYVVKHRKQVTNSSDDWTISGIPASQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPKPEIVASKEQQIQRDDPGAGPQSSSQPDHGRLSPPEAPDRPTISMASETSVYVTWIPRGNGGFPIQSFRVEYKKLKKVGDWILATSAIPPSRLSVEITGLEKGTSYKFRVRALNMLGESEPSAPSRPYVVSGYSSRVYERPVAGPYITFTDAVNETTIMLKWMYIPASNNNTPIHGFYIYYRPTDSDNDSDYKKDMVEGDRYWHSISHLQPETSYDIKMQCFNEGGESEFSNVMICETKARKSSGQPGRLPPPTLAPPQPPPPETMERPVGTGAMVARSSDLPYLIVGVVLGSVVLIIVAFIPFCLWRAWSKQKHTTDLGFPRSALLSSSCQYTMVPLGGLPGHRASGQPYLSGTNGRACANGVRMNRACPVAAMGYPGVKPQQHCPGELQQQEDVNSVLRQTFLGNGYNPHSPQIPRAPRSNPDEGTFLYTLPDDSAHQLLPPHRDCHHLQEQPEATGQPGTRSVPQSPGLEAVWDPVFHPGPPCCLGLVPVEEVDSPDSCPVGRGDWCPQHPSGSYAGQELGVRLSPSPPVHVSFETPPPTI", "length": 1116, "header": "tr|A0ABI0NNV1-1|A0ABI0NNV1_BOVIN Isoform 1 of Brother of CDO OS=Bos taurus OX=9913 GN=BOC PE=4 SV=1 CANONICAL=A0ABI0NNV1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NNV1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1/entry#A0ABI0NNV1-1", "sequence": { "sequence": "MPRGMMAMQRGKQPEVTLACLLLAAAGCFADLNEVPQVTVQPSSTVQKLGGTVILGCVVEPPWMNTTWRLNGRELNGSDDSLGILITRGTLVVTALNNHTVGRYQCVARMPAGAVASVPATVTLANLQDFKLDVQHVIEVDEGNTAVIACHLPESHPKAQVRYSVKQEWLEASRDNYLIMPSGNLQIVNASQEDEGMYKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPPEAQTIVVTKGQSLILECVASGIPPPRVTWAKDGSSVASYNKTRFLLSNLLIDTTNEEDSGTYRCMADNGVGEPGAAVILYNVQVFEPPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLTSSQRLRLSHRALRVVSMGPEDEGVYQCMAENEVGSAHAVVQLKTARPGTTLRPWWDAQSATVTPPVPPSRPGGPDQMPKGHPGLLRPQASEQPASPQCPGDQGPVAPAEAPIILSSPRTSKTDSYELVWRPRHEGSSRAPVLYYVVKHRKQVTNSSDDWTISGIPASQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPKPEIVASKEQQIQRDDPGAGPQSSSQPDHGRLSPPEAPDRPTISMASETSVYVTWIPRGNGGFPIQSFRVEYKKLKKVGDWILATSAIPPSRLSVEITGLEKGTSYKFRVRALNMLGESEPSAPSRPYVVSGYSSRVYERPVAGPYITFTDAVNETTIMLKWMYIPASNNNTPIHGFYIYYRPTDSDNDSDYKKDMVEGDRYWHSISHLQPETSYDIKMQCFNEGGESEFSNVMICETKARKSSGQPGRLPPPTLAPPQPPPPETMERPVGTGAMVARSSDLPYLIVGVVLGSVVLIIVAFIPFCLWRAWSKQKHTTDLGFPRSALLSSSCQYTMVPLGGLPGHRASGQPYLSGTNGRACANGVRMNRACPVAAMGYPGVKPQQHCPGELQQQEDVNSVLRQTFLGNGYNPHSPQIPRAPRSNPDEGTFLYTLPDDSAHQLLPPHRDCHHLQEQPEATGQPGTRSVPQSPGLEAVWDPVFHPGPPCCLGLVPVEEVDSPDSCPVGRGDWCPQHPSGSYAGQELGVRLSPSPPVHVSFETPPPTI", "length": 1116, "header": "tr|A0ABI0NNV1-1|A0ABI0NNV1_BOVIN Isoform 1 of Brother of CDO OS=Bos taurus OX=9913 GN=BOC PE=4 SV=1 CANONICAL=A0ABI0NNV1-1" }, "locus": { "chromosome": "1", "start_pos": 58021138, "end_pos": 57984296, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153371.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153371.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107447.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107447.1" } ] } }, { "isoform_ac": "E1BB93-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1/entry#E1BB93-1", "sequence": { "sequence": "MNTTWRLNGRELNGSDDSLGILITRGTLVVTALNNHTVGRYQCVARMPAGAVASVPATVTLANLQDFKLDVQHVIEVDEGNTAVIACHLPESHPKAQVRYSVKQEWLEASRDNYLIMPSGNLQIVNASQEDEGMYKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPPEAQTIVVTKGQSLILECVASGIPPPRVTWAKDGSSVASYNKTRFLLSNLLIDTTNEEDSGTYRCMADNGVGEPGAAVILYNVQVFEPPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLTSSQRLRLSHRALRVVSMGPEDEGVYQCMAENEVGSAHAVVQLKTARPGTTLRPWWDAQSATVTPPVPPSRPGGPDQMPKGHPGLLRPQASEQPASPQCPGDQGPVAPAEAPIILSSPRTSKTDSYELVWRPRHEGSSRAPVLYYVVKHRKVTNSSDDWTISGIPASQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPKPEIVASKEQQIQRDDPGAGPQSSSQPDHGRLSPPEAPDRPTISMASETSVYVTWIPRGNGGFPIQSFRVEYKKLKKVGDWILATSAIPPSRLSVEITGLEKGTSYKFRVRALNMLGESEPSAPSRPYVVSGYSSRVYERPVAGPYITFTDAVNETTIMLKWMYIPASNNNTPIHGFYIYYRPTDSDNDSDYKKDMVEGDRYWHSISHLQPETSYDIKMQCFNEGGESEFSNVMICETKARKSSGQPGRLPPPTLAPPQPPPPETMERPVGTGAMVARSSDLPYLIVGVVLGSVVLIIVAFIPFCLWRAWSKQKHTTDLGFPRSALLSSSCQYTMVPLGGLPGHRASGQPYLSGTNGRACANGVRMNRACPVAAMGYPGVKPQQHCPGELQQQEDVNSVLRQTFLGNGYNPHSPQIPRAPRSNPDEGTFLYTLPDDSAHQLLPPHRDCHHLQEQPEATGQPGTRSVPQSPGLEAVWDPVFHPGPPCCLGLVPVEEVDSPDSCPVGRGDWCPQHPSGSYAGQELGVRLSPSPPVHVSFETPPPTI", "length": 1052, "header": "tr|E1BB93-1|A0ABI0NNV1_BOVIN Computationally mapped isoform of Brother of CDO OS=Bos taurus OX=9913 GN=BOC PE=4 SV=2 CANONICAL=A0ABI0NNV1-1" }, "locus": { "chromosome": "1", "start_pos": 58021138, "end_pos": 57985161, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018474.7", "url": "https://www.ensembl.org/id/ENSBTAT00000018474.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018474.5", "url": "https://www.ensembl.org/id/ENSBTAP00000018474.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:512018", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512018", "resource": "KEGG Pathway" }, { "id": "R-BTA-525793", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-525793", "resource": "Reactome", "description": "Myogenesis" }, { "id": "R-BTA-5635838", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5635838", "resource": "Reactome", "description": "Activation of SMO" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JNN3-1", "protein_name": "Brother of CDO", "gene_name": "Boc", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTTCRGKPPTVALVGLLWAAASCLADLGEVPQVTVQPMSTVQKLGGTVILGCVVEPPWVNVTWRFNGKELNGSDNALGVLVTRRTLVIASLNNHTVGRYQCVARIPAGAVASVPATVTLANLQDFKLDVQHVIEVDEGNTAVIACHLPESHPKAQVRYSVKQEWLEASRDNYLIMPSGNLQIVNASQEDEGMYKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPLEAQTVIVTKGQSLILECVASGIPPPQVTWAKDGSSIAGYNKTRFLLSNLLIDTTSEEDSGTYRCMASNGVGEPGAAVILYNVQVFEPPEVTVELSQLVIPWGESAKLTCEVRGNPPPSVLWLRNAVPLTSSQRLRLSRRALRVVSVGPEDEGVYQCMAENEVGSAHAVVQLRTARPDTTLRPGRDAKPIAATPPLPPSRPSRPDQMLQEQLGLVKPPTSIQPTSQKCLGEEQVTPAEAPIILSSPRTSKTDSYELVWRPRHEGSSQAPILYYVVKHRKQVTNASDDWTISGIPANQHHLTLTSLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPKPEIVASKEQQIQRDDPGTSPQSSSQPDHGRLSPPEAPDRPTISMASETSVYVTWIPRGNGGFPIQSFRVEYKKLKKVGDWILATSAIPPSRLSVEITGLEKGISYKFRVRALNMLGESEPSAPSRPYVVSGYSGRVYERPVAGPYITFTDAVNETTIMLKWMYIPASNNNTPIHGFYIYYRPTDSDNDSDYKKDMVEGDRYWHSISHLQPETSYDIKMQCFNEGGESEFSNVMICETKARKISGQPGRPPPLTLAPPQPPPLETMERPVGTGAMVARASDLPYLIVGVVLGSIVLIIVTFIPFCLWRAWSKQKHTTDLGFPRSAILSSSCQYTMVPLGGLPGHQANGQPYLSGINGRACASQLLGSRACSAAAVGCPGRKPQQHCLGELAQQQEDTNSPLRQTMVGNGYDPQSQQVARGPKSSSEEGSFLYTLSDDSTHQLLQTQDCCHLQKQPVTTCQTATRRAPEGPGPEASWDPPYHSGPRCCLGLVPVEEVDSFDSCQVGGEDWCPQHLAYTGQELGVQLSPSPSVHVSFETPPPTI", "length": 1108 }, "evidence": [ { "id": "A0ABI0NNV1", "url": "https://omabrowser.org/oma/group/A0ABI0NNV1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A8JUV7-1", "protein_name": "Interference hedgehog", "gene_name": "boi", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAEIRLVVVLLVLMTTCIYTLQASDSNSSVATTLGVLFERAPESAVAPKGDEVVFECELNLKPDRLEWRFRRGDSSEPYLYLRPSAGYNVTSGSDGLAWRLRIYVSAQTAGDYQCVAWYGPGALASTPARLALVSIALDVGQGSMGARSSIRWSVAPKNCLLIRCGSVISNPPAIWSFYRNGKKLPQSELLPGAAGALVLDTVTAKDAGNYSCVATNSITGDELRLPQTIELRVDYTDRTPPYFLQRPPIEYSARPGETVVLECPGVGSPRPRVIWSSPNVVEIYNNRSTILSYGLQITDVKPEDQGSYICMLDNGIAPPIDHTIKLSVLQRPTILRGPAATLTNESNPLLLDCSASGNPQPDIYWLINGEDATKDPEAVVDNRSLQLKRVQKRHAGVVQCFAKNILGETSEGNILRVNPLEITGEDDEPLGEVPVWPVHESNTGMGTSSTSGGSKNKSGRRKFKASMVPPSRPNVTRLSDESVMLRWSVPQNSGLQITFFKVQYRMLGDGKNRRKNWQTTSDNIPYGNAHGSGPGQGNSHWRARNRDREYEMGNPPKNFTSSVTGLTAGKYYRFRIVAVYSNNDNKEGNTSLKFFLQNGTSKSNLPVPELREVETLSESAVVLHWSLVSSTQNEDIDGYYAYYRPADSAAEYLKATVDGGMSRSFKIDLLRPGTPYEFKLQSFNSDAASEFSAIRQARTRKTHEQPASSSATPVPANKAVEQHQNSLYPLIAGAAGGGILLLIASLVVCLCLKRRENSQPEDENKPQLEHIQADFVTSAVLGVGGHHKSGDVRRLNGVIPRMNITPNPLAQETASDKNRNVMELRFLPPLANGNGNGNCMARDLALERSNAEEQQDEDGHEDEKGLPAVASSSCETLEACDAAIKLNLPQKHDQEQLDAPNAVLEAPSKPLPPLPKKPANGAGQNNSGLHQNGLHHAQPYHPPGTPTLMHKRLDYHQQPPPVPPHSAYYQQAPTHQPSPMMERSVRGHQQPGGFHMEEGTPTPTRIPSLRRQRRTSGNQQVHNSHSNLNIGLSHHNNNNNNLPPHHQHLHHHPGHPGGLVGIPIVPGSPRVQRSPMPSRAMIKRTRLGSHTDNISSGSLNSIEV", "length": 1105 }, "evidence": [ { "id": "A0ABI0NNV1", "url": "https://omabrowser.org/oma/group/A0ABI0NNV1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D4A0Z7-1", "protein_name": "Brother of CDO", "gene_name": "Boc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVTCRGEQPMLTLLWFLLAIAGCLADLNEVPQVTVQPMSTVQKLGGTVILGCVVEPPWVNVTWRFNGKELNGSDDALGVLITRGTLVIAALNNHTVGRYQCVARMPAGAVASVPATVTLANLQDFKLDVQHVIEVDEGNTAVIACHLPESHPKAQVRYSVKQEWLEASRDNYLIMPSGNLQIVNASQEDEGTYKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPLEAQTVIVTKGQSLILECVASGIPPPRVTWAKDGSSIAAYNKTRFLLSNLLIDTTSEEDSGTYRCMASNGVGDPGAAVILYNVQVFEPPEVTVELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLSSNQRLRLSRKALRVVSVRPEDEGVYQCMAENAVGSAHAVVQLRTARPDTTLRPGRDTKPIAATPPMPPSRPNRPDQMLREQPGLVKPPTSVQPTSLKCLGEEQVAPAEAPVILSSPRTSKTDSYELVWRPRHEGSSRAPILYYVVKHRKVTNSSDDWIISGIPANQHHLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPKPEIVASKEQQIQRDDPGASLQSSSQPDHGRLSPPEAPDRPTISTASETSVYVTWIPRGNGGFPIQSFRVEYKKLKKVGDWILATSAIPPSRLSVEITGLEKGISYKFRVRALNMLGESEPSAPSRPYVVSGYSGRVYERPVAGPYITFTDAVNETTIMLKWMYIPASNNNTPIHGFYIYYRPTDSDNDSDYKKDMVEGDRYWHSISHLQPETSYDIKMQCFNEGGESEFSNVMICETKARKFSGQPGRPPPLTLAPPQPPPLEAMERPMGTGAMVARASDLPYLIVGVVLGSIVLIIVTFIPFCLWRAWSKQKHTTDLGFPRSALLSSSCQYTMVPLGGLPGHQANGQPYLSGIGGRACVSRLHGSRGYPAATVGCPGRKLQQHCPGELAQQREDSNSLLRQPIVSNGYDLQNQQVARGTKSGSEEGSFLYTLPDDSTHQLLQPQDCCHLQKQPVTTCQTAVRRAPEGPGLEASWDPQYHSGPRCCLGLVPVEEVDSSDSCQVGGGDCCPQHPSGTYTGQELGVRLSPSPSVHVSFETPPPTI", "length": 1109 }, "evidence": [ { "id": "A0ABI0NNV1", "url": "https://omabrowser.org/oma/group/A0ABI0NNV1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AZB0-1", "protein_name": "Brother of CDO", "gene_name": "Boc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTCRRERPILTLLWILMATAGCLADLNEVPQVTVQPMSTVQKLGGTVILGCVVEPPWMNVTWRFNGKELNGSDDALGVFITRGTLVIAALNNHTVGRYQCVARMPAGAVASVPATVTLANLQDFKLDVQHVIEVDEGNTAVIACHLPESHPKAQVRYSVKQEWLEASRDNYLIMPSGNLQIVNASQEDEGMYKCAAYNPVTQEVKTSGSGDRLRVRRSTAEAARIIYPLEAQTVIVTKGQSLILECVASGIPPPRVTWAKDGSSIAAYNKTRFLLSNLLIDTTSEEDSGTYRCMASNGVGDPGAAVILYNVQVFEPPEVTVELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLTSSQRLRLSRRALRVVSVGPEDEGVYQCMAENAVGSAHAVVQLRTARPDTTLRPGRDTKPIAATPPMPPSRPSRPDQMLREQPGLVKPPTSSVQPTSLKCPGEEQVAPAEAPIILSSPRTSKTDSYELVWRPRHEGSSRTPILYYVVKHRKVTNSSDDWTISGIPANQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPKPEIVASKEQQIQRDDPGASLQSSSQPDHGRLSPPEAPDRPTISTASETSVYVTWIPRGNGGFPIQSFRVEYKKLKKVGDWILATSAIPPSRLSVEITGLEKGISYKFRVRALNMLGESEPSAPSRPYVVSGYSGRVYERPVAGPYITFTDAVNETTIMLKWMYIPASNNNTPIHGFYIYYRPTDSDNDSDYKKDMVEGDRYWHSISHLQPETSYDIKMQCFNEGGESEFSNVMICETKARKFSGQPGRPPPLTLAPPQPPPLETMERPVGTGAMVARASDLPYLIVGVVLGSIVLIIVTFIPFCLWRAWSKQKHTTDLGFPRSALLSSSCQYTMVPLEGLPGHQANGQPYLGGVSGRACVSRVHGSRGCPAATVGCPGRKPQQHCPGELAQQREDTNSQLRQPIVSNGYDLQNQQVARGPQCASGVGAFLYTLPDDSTHQLLQPQDCCHLQKQPVTTCQTAVRRTSESPGLESSWDPPYHSGPRCCLGLVPVEEVDSSDSCQVGGGDWSSQHPSGTYTGQERGMRFSPSPSVHVSFETPPPTI", "length": 1110 }, "evidence": [ { "id": "A0ABI0NNV1", "url": "https://omabrowser.org/oma/group/A0ABI0NNV1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BWV1-1", "protein_name": "Brother of CDO", "gene_name": "BOC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRGTMTAWRGMRPEVTLACLLLATAGCFADLNEVPQVTVQPASTVQKPGGTVILGCVVEPPRMNVTWRLNGKELNGSDDALGVLITHGTLVITALNNHTVGRYQCVARMPAGAVASVPATVTLANLQDFKLDVQHVIEVDEGNTAVIACHLPESHPKAQVRYSVKQEWLEASRGNYLIMPSGNLQIVNASQEDEGMYKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPRVTWAKDGSSVTGYNKTRFLLSNLLIDTTSEEDSGTYRCMADNGVGQPGAAVILYNVQVFEPPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSRRALRVLSMGPEDEGVYQCMAENEVGSAHAVVQLRTSRPSITPRLWQDAELATGTPPVSPSKLGNPEQMLRGQPALPRPPTSVGPASPQCPGEKGQGAPAEAPIILSSPRTSKTDSYELVWRPRHEGSGRAPILYYVVKHRKVTNSSDDWTISGIPANQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPKPEIMASKEQQIQRDDPGASPQSSSQPDHGRLSPPEAPDRPTISTASETSVYVTWIPRGNGGFPIQSFRVEYKKLKKVGDWILATSAIPPSRLSVEITGLEKGTSYKFRVRALNMLGESEPSAPSRPYVVSGYSGRVYERPVAGPYITFTDAVNETTIMLKWMYIPASNNNTPIHGFYIYYRPTDSDNDSDYKKDMVEGDKYWHSISHLQPETSYDIKMQCFNEGGESEFSNVMICETKARKSSGQPGRLPPPTLAPPQPPLPETIERPVGTGAMVARSSDLPYLIVGVVLGSIVLIIVTFIPFCLWRAWSKQKHTTDLGFPRSALPPSCPYTMVPLGGLPGHQASGQPYLSGISGRACANGIHMNRGCPSAAVGYPGMKPQQHCPGELQQQSDTSSLLRQTHLGNGYDPQSHQITRGPKSSPDEGSFLYTLPDDSTHQLLQPHHDCCQRQEQPAAVGQSGVRRAPDSPVLEAVWDPPFHSGPPCCLGLVPVEEVDSPDSCQVSGGDWCPQHPVGAYVGQEPGMQLSPGPLVRVSFETPPLTI", "length": 1114 }, "evidence": [ { "id": "A0ABI0NNV1", "url": "https://omabrowser.org/oma/group/A0ABI0NNV1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNV1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNV1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNV1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNV1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 726, "end_pos": 728, "annotation": "n_glycosylation_sequon" }, { "start_pos": 742, "end_pos": 744, "annotation": "n_glycosylation_sequon" }, { "start_pos": 760, "end_pos": 762, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NNV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 474, "end_pos": 572, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NNV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNV1" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 123, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 518, "end_pos": 520 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 726, "end_pos": 728 }, { "start_pos": 742, "end_pos": 744 }, { "start_pos": 760, "end_pos": 762 }, { "start_pos": 76, "end_pos": 78 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NSP8-1", "uniprot_ac": "A0ABI0NSP8", "uniprot_id": "A0ABI0NSP8_BOVIN", "mass": { "chemical_mass": 51118.0, "monoisotopic_mass": 51118.0 }, "refseq": { "ac": "NP_001193055", "name": "mitochondrial dynamics protein MIEF1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193055" }, "gene_names": [ { "name": "MIEF1", "type": "recommended", "evidence": [ { "id": "A0ABI0NSP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8" } ] }, { "name": "MIEF1", "type": "synonym", "evidence": [ { "id": "NP_001193055", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193055" } ] }, { "name": "SMCR7L", "type": "synonym", "evidence": [ { "id": "NP_001193055", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193055" } ] } ], "protein_names": [ { "name": "Mitochondrial elongation factor 1", "type": "recommended", "evidence": [ { "id": "A0ABI0NSP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8/entry#names_and_taxonomy" } ] }, { "name": "Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like", "type": "synonym", "evidence": [ { "id": "A0ABI0NSP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8/entry#names_and_taxonomy" } ] }, { "name": "Smith-Magenis syndrome chromosome region, candidate 7-like", "type": "synonym", "evidence": [ { "id": "NP_001193055", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193055" } ] }, { "name": "mitochondrial dynamics protein MIEF1", "type": "synonym", "evidence": [ { "id": "NP_001193055", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193055" } ] } ], "function": [ { "annotation": "Mitochondrial outer membrane protein which regulates mitochondrial fission/fusion dynamics. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.", "evidence": [ { "database": "UniProtKB", "id": "E1BIT2", "url": "https://www.uniprot.org/uniprotkb/E1BIT2#function" }, { "database": "UniProtKB", "id": "ARBA00055566", "url": "https://www.uniprot.org/uniprotkb/ARBA00055566#function" }, { "database": "UniProtKB", "id": "A0ABI0NSP8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSP8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MIEF1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8", "locus": { "chromosome": "5", "start_pos": 110943173, "end_pos": 110928312, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017439", "url": "https://www.ensembl.org/id/ENSBTAG00000017439" } ] } } ], "crossref": [ { "id": "ENSBTAG00000017439", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017439", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613306", "url": "https://www.ncbi.nlm.nih.gov/gene/613306", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613306", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613306", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEKEGDW", "url": "https://omabrowser.org/oma/group/CEKEGDW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIT2", "url": "https://www.orthodb.org/?gene=E1BIT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16451", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16451", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16451:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16451:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001193055", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193055", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NSP8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSP8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIT2", "url": "https://www.uniprot.org/uniprotkb/E1BIT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIT2-1", "url": "https://www.uniprot.org/uniprotkb/E1BIT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGSGERKSKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSPTRLSHSGKRSWEEPNWMGSPRLLNKDMKAGLSRSLQALPTGSSAFDTDTFCPPRPKPLARKGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEVQYERDKHLVIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCRSLCLKILKAVCKSTPALGRLTASQLTNVILHLAQEEADWSPDVLADRFLQALRGLISHLEAGILPSVLNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT", "length": 463, "header": "tr|A0ABI0NSP8-1|A0ABI0NSP8_BOVIN Isoform 1 of Mitochondrial elongation factor 1 OS=Bos taurus OX=9913 GN=MIEF1 PE=4 SV=1 CANONICAL=A0ABI0NSP8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NSP8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8/entry#A0ABI0NSP8-1", "sequence": { "sequence": "MAGSGERKSKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSPTRLSHSGKRSWEEPNWMGSPRLLNKDMKAGLSRSLQALPTGSSAFDTDTFCPPRPKPLARKGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEVQYERDKHLVIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCRSLCLKILKAVCKSTPALGRLTASQLTNVILHLAQEEADWSPDVLADRFLQALRGLISHLEAGILPSVLNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT", "length": 463, "header": "tr|A0ABI0NSP8-1|A0ABI0NSP8_BOVIN Isoform 1 of Mitochondrial elongation factor 1 OS=Bos taurus OX=9913 GN=MIEF1 PE=4 SV=1 CANONICAL=A0ABI0NSP8-1" }, "locus": { "chromosome": "5", "start_pos": 110940531, "end_pos": 110936746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142943.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142943.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106034.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106034.1" } ] } }, { "isoform_ac": "E1BIT2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8/entry#E1BIT2-1", "sequence": { "sequence": "MASLTRWTCAMAGSGERKSKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSPTRLSHSGKRSWEEPNWMGSPRLLNKDMKAGLSRSLQALPTGSSAFDTDTFCPPRPKPLARKGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEVQYERDKHLVIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCRSLCLKILKAVCKSTPALGRLTASQLTNVILHLAQEEADWSPDVLADRFLQALRGLISHLEAGILPSVLNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT", "length": 473, "header": "tr|E1BIT2-1|A0ABI0NSP8_BOVIN Computationally mapped isoform of Mitochondrial elongation factor 1 OS=Bos taurus OX=9913 GN=MIEF1 PE=4 SV=2 CANONICAL=A0ABI0NSP8-1" }, "locus": { "chromosome": "5", "start_pos": 110940531, "end_pos": 110932601, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023204.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023204.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023204.5", "url": "https://www.ensembl.org/id/ENSBTAP00000023204.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:613306", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613306", "resource": "KEGG Pathway" }, { "id": "R-BTA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ALN3-1", "protein_name": "Mitochondrial elongation factor 1", "gene_name": "MIEF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGAGERKSKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSPTRLSHSGKRSWEEPNWMGSPRLLNKDMKTGLSRSLQTLPTGSSAFDTDTFCPPRPKPLARKGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCVPGEDTIMNVPGFFLVRRENPEYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPGALTLEVQYERDKHLVIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCRSLCLKILKAICKSTPALGHLTASQLTSVILHLAQEEADWSPDMLADRFLQALRGLISYLEAGVLPSALNPKVNLFAELTPEEVDELGYTLYCSLSEPEVLLQT", "length": 463 }, "evidence": [ { "id": "A0ABI0NSP8", "url": "https://omabrowser.org/oma/group/A0ABI0NSP8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A4IG61-1", "protein_name": "Mitochondrial dynamics protein MID51", "gene_name": "mief1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGVNGDRKGKKDDNGLGTAIDFVLSNAKLVLGVGGAAMLGIATLAVKRMYDRALSAPSSPTKADPSGRRSWEEPSWLGSSPRTLNHDMKQNVSRSLQTLPTSSSSFKPDSLHRGLARGGRPAKAELQRARLRLSLQEHLWAFFHERVTIPSEEQSVARRAALDICAELRVFLHAKLPDMPLREMYLSGSLYDDLQVVTADHAQLMVPLILEKNLWSSIPGEDTIMNIPGFSLVRRENLEYFPRGSSYWDRCMVGGYLSPKSVLEVFEKLVAGSINWPAIGSVLDYVIRPVVPSETLTLEVQYETDRRLYVDFLPLLVMEDGVSLIAKPHRLAAERHENLWRQSFRVAETAKLRALDQEDAGCRSVCLKILKAVCKLNPALARLNASQLTNAILLLSEQEGDWTQEALADRFMQLLRALVGHLEAGRMPCTLNLKVNLLCELTPQEIDELGYTLYCALSDPESLLRTV", "length": 468 }, "evidence": [ { "id": "A0ABI0NSP8", "url": "https://omabrowser.org/oma/group/A0ABI0NSP8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BVG4-1", "protein_name": "Mitochondrial elongation factor 1", "gene_name": "MIEF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGAGPRKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPSSPTRLNQSGKRSWEEPNWLGSSSRLLSQDMKTNLSRSLQTLPTESSATDTDFFRPTKPKPSAKRSQVELKKSRLRLSLQEKLFAYYRRKVAIPTDEQALAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLMLEQNLWSCIPGEETIMNIPGFYLVRRENPEYFPRGSSYWDRCVVGGYLSPKAVAETFEKVVAGSINWPAIGSLLDYVIRPAAPPADLTLEVQYDPERRLFIDFLPSLTLGDIVLVAKPHRLAQNDNLWRLSLRPAETARLRALDQCDSGCRCLCLKIFKAVCKLNPALGHLTASQLTNVILHLSQEESNWSQDVLADRFLQALKGLIRYLEAGVLPSALNPKVNLFSELTPEEVDELGYTLYSSLSEPEVLLQT", "length": 464 }, "evidence": [ { "id": "A0ABI0NSP8", "url": "https://omabrowser.org/oma/group/A0ABI0NSP8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5XIS8-1", "protein_name": "Mitochondrial dynamics protein MID51", "gene_name": "Mief1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSPTRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSAFDTDTFCPPRPKPLARRGQVDLKKSRLRMSLQEKLLSYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNIPGFFLVRRENPEYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEVQYERDKHLVIDFLPSVTLGDTVLVARPHRLAQYDNLWRLSLRPAETARLRALDQADSGCRSLCLKILKAICKSTPALGHLTASQLTNVILHLSQEEADWSPDMLADRFLQALRGLISYLEAGVLPSALNPKVNLFAELTPHEIDELGYTLYCSLSEPEVLLQT", "length": 463 }, "evidence": [ { "id": "A0ABI0NSP8", "url": "https://omabrowser.org/oma/group/A0ABI0NSP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BGV8-1", "protein_name": "Mitochondrial dynamics protein MID51", "gene_name": "Mief1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSPTRLSHSGKRSWEEPNWMGSPRLLNKDMKAGLSRSLQTLPTDSSAFDTDTFCPPRPKPLARRGQVDLKKSRLRMSLQEKLLSYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEVQYEKDKHLVIDFLPSVTLGDTVLVARPHRLAQYDNLWRLSLRPAETARLRALDQADSGCRSLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLEAGVLPSALNPKVNLFAELTPQEIDELGYTLYCSLSEPEVLLQT", "length": 463 }, "evidence": [ { "id": "A0ABI0NSP8", "url": "https://omabrowser.org/oma/group/A0ABI0NSP8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQG6-1", "protein_name": "Mitochondrial dynamics protein MIEF1", "gene_name": "MIEF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSPTRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVARKGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEVQYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCRSLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLEAGVLPSALNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT", "length": 463 }, "evidence": [ { "id": "A0ABI0NSP8", "url": "https://omabrowser.org/oma/group/A0ABI0NSP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of mitochondrial fusion", "id": "GO:0010636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010636", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSP8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8" } ], "pmid": "" }, { "name": "positive regulation of protein targeting to membrane", "id": "GO:0090314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090314", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSP8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8" } ], "pmid": "" }, { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSP8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial fission", "id": "GO:0090141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090141", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSP8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSP8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSP8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSP8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8" } ], "pmid": "" }, { "name": "ADP binding", "id": "GO:0043531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043531", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSP8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8" } ], "pmid": "" }, { "name": "GDP binding", "id": "GO:0019003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019003", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSP8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NSP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8" }, { "id": "PF20266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mab-21-like HhH/H2TH-like", "eco_id": "ECO_0000259", "start_pos": 359, "end_pos": 446, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NSP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSP8" }, { "id": "PF21297", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21297" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mitochondrial dynamics protein MID51-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 153, "end_pos": 345, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQG3-1", "uniprot_ac": "A0ABI0NQG3", "uniprot_id": "A0ABI0NQG3_BOVIN", "mass": { "chemical_mass": 103211.0, "monoisotopic_mass": 103211.0 }, "refseq": {}, "gene_names": [ { "name": "UBC", "type": "recommended", "evidence": [ { "id": "A0ABI0NQG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQG3" } ] } ], "protein_names": [ { "name": "Ubiquitin C", "type": "synonym", "evidence": [ { "id": "A0ABI0NQG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQG3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQG3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQG3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UBC", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQG3", "locus": { "chromosome": "17", "start_pos": 50892468, "end_pos": 50887544, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000032436", "url": "https://www.ensembl.org/id/ENSBTAG00000032436" } ] } } ], "crossref": [ { "id": "cd01803", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01803", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NQG3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQG3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS03", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS03-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGVLSSPF", "length": 918, "header": "tr|A0ABI0NQG3-1|A0ABI0NQG3_BOVIN Isoform 1 of Ubiquitin C OS=Bos taurus OX=9913 GN=UBC PE=3 SV=1 CANONICAL=A0ABI0NQG3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NQG3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQG3/entry#A0ABI0NQG3-1", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGVLSSPF", "length": 918, "header": "tr|A0ABI0NQG3-1|A0ABI0NQG3_BOVIN Isoform 1 of Ubiquitin C OS=Bos taurus OX=9913 GN=UBC PE=3 SV=1 CANONICAL=A0ABI0NQG3-1" }, "locus": { "chromosome": "17", "start_pos": 50891977, "end_pos": 50889224, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145835.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145835.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104479.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104479.1" } ] } }, { "isoform_ac": "A0ABI0NS03-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQG3/entry#A0ABI0NS03-1", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGVLSSPF", "length": 842, "header": "tr|A0ABI0NS03-1|A0ABI0NS03_BOVIN Computationally mapped isoform of Ubiquitin C OS=Bos taurus OX=9913 GN=UBC PE=3 SV=1 CANONICAL=A0ABI0NQG3-1" }, "locus": { "chromosome": "17", "start_pos": 50891977, "end_pos": 50889452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140893.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140893.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105645.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105645.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NQG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQG3" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 76, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NRV0-1", "uniprot_ac": "A0ABI0NRV0", "uniprot_id": "A0ABI0NRV0_BOVIN", "mass": { "chemical_mass": 60219.0, "monoisotopic_mass": 60219.0 }, "refseq": {}, "gene_names": [ { "name": "RIC8A", "type": "recommended", "evidence": [ { "id": "A0ABI0NRV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRV0" } ] } ], "protein_names": [ { "name": "Synembryn", "type": "recommended", "evidence": [ { "id": "A0ABI0NRV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRV0/entry#names_and_taxonomy" } ] }, { "name": "Protein Ric-8", "type": "synonym", "evidence": [ { "id": "A0ABI0NRV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRV0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Chaperone that specifically binds and folds nascent G alpha proteins prior to G protein heterotrimer formation. Also acts as a guanine nucleotide exchange factor (GEF) for G alpha proteins by stimulating exchange of bound GDP for free GTP.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NIX4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIX4#function" }, { "database": "UniProtKB", "id": "RU369048", "url": "https://www.uniprot.org/uniprotkb/RU369048#function" }, { "database": "UniProtKB", "id": "ARBA00049572", "url": "https://www.uniprot.org/uniprotkb/ARBA00049572#function" }, { "database": "UniProtKB", "id": "A0ABI0NRV0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRV0#function" }, { "database": "UniProtKB", "id": "A0ABI0P1P8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRV0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRV0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RIC8A", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRV0", "locus": {} } ], "crossref": [ { "id": "IPR008376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019318", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019318", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12425", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12425", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12425:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12425:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10165", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10165", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NIX4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NIX4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRV0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRV0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1P8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1P8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPRAVADALETGEEDVVMEALRAYNRENSQSFTFDDAQQEDRKRLAKLLVSVLEQGLPPSRRVIWLQSIRILSRDRSCLDSFTSRRSLQALACYAGISASQGSVPEPLNMDVVLESLKCLCNLVLSSPVAQALAAEAGLVVRLAERVGLCRQSSFPHDVQFFDLRLLFLLTALRTDVRQQLFQELQGVRLLTRALELTLGMTEGERHPELLPPQETERAMEILKVLFNITFDSIKREVDEEDAALYRHLGTLLRHCVMLAAAGDRTEELHGHAVNLLGNLPVKCLDVLLTLEPHEGSLEFLGVNMDVIRVLLSFMEKRLHQTHRLKESVAPVLSVLTECARMHRPARKFLKAQRQLPPQVLPPLRDVRTRPEVGELLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVNMFDKLSRHRVIQPMGMSPRGQLTSLQDAMCETMEGQLSSDPDSDPD", "length": 536, "header": "tr|A0ABI0NRV0-1|A0ABI0NRV0_BOVIN Isoform 1 of Synembryn OS=Bos taurus OX=9913 GN=RIC8A PE=3 SV=1 CANONICAL=A0ABI0NRV0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NIX4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRV0/entry#A0ABI0NIX4-1", "sequence": { "sequence": "MEPRAVADALETGEEDVVMEALRAYNRENSQSFTFDDAQQEDRKRLAKLLVSVLEQGLPPSRRVIWLQSIRILSRDRSCLDSFTSRRSLQALACYAGISASQGSVPEPLNMDVVLESLKCLCNLVLSSPVAQALAAEAGLVLFQELQGVRLLTRALELTLGMTEGERHPELLPPQETERAMEILKVLFNITFDSIKREVDEEDAALYRHLGTLLRHCVMLAAAGDRTEELHGHAVNLLGNLPVKCLDVLLTLEPHEGSLEFLGVNMDVIRVLLSFMEKRLHQTHRLKESVAPVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGELLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVNMFDKLSRHRVIQPMGMSPRGQLTSLQDAMCETMEGQLSSDPDSDPD", "length": 490, "header": "tr|A0ABI0NIX4-1|A0ABI0NRV0_BOVIN Computationally mapped isoform of Synembryn OS=Bos taurus OX=9913 GN=RIC8A PE=3 SV=1 CANONICAL=A0ABI0NRV0-1" }, "locus": { "chromosome": "11", "start_pos": 82878210, "end_pos": 82873544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147977.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147977.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104248.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104248.1" } ] } }, { "isoform_ac": "A0ABI0NRV0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRV0/entry#A0ABI0NRV0-1", "sequence": { "sequence": "MEPRAVADALETGEEDVVMEALRAYNRENSQSFTFDDAQQEDRKRLAKLLVSVLEQGLPPSRRVIWLQSIRILSRDRSCLDSFTSRRSLQALACYAGISASQGSVPEPLNMDVVLESLKCLCNLVLSSPVAQALAAEAGLVVRLAERVGLCRQSSFPHDVQFFDLRLLFLLTALRTDVRQQLFQELQGVRLLTRALELTLGMTEGERHPELLPPQETERAMEILKVLFNITFDSIKREVDEEDAALYRHLGTLLRHCVMLAAAGDRTEELHGHAVNLLGNLPVKCLDVLLTLEPHEGSLEFLGVNMDVIRVLLSFMEKRLHQTHRLKESVAPVLSVLTECARMHRPARKFLKAQRQLPPQVLPPLRDVRTRPEVGELLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVNMFDKLSRHRVIQPMGMSPRGQLTSLQDAMCETMEGQLSSDPDSDPD", "length": 536, "header": "tr|A0ABI0NRV0-1|A0ABI0NRV0_BOVIN Isoform 1 of Synembryn OS=Bos taurus OX=9913 GN=RIC8A PE=3 SV=1 CANONICAL=A0ABI0NRV0-1" }, "locus": { "chromosome": "11", "start_pos": 82878210, "end_pos": 82873544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143233.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143233.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105423.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105423.1" } ] } }, { "isoform_ac": "A0ABI0P1P8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRV0/entry#A0ABI0P1P8-1", "sequence": { "sequence": "MEPRAVADALETGEEDVVMEALRAYNRERLAKLLVSVLEQGLPPSRRVIWLQSIRILSRDRSCLDSFTSRRSLQALACYAGISASQGSVPEPLNMDVVLESLKCLCNLVLSSPVAQALAAEAGLVVRLAERVGLCRQSSFPHDVQFFDLRLLFLLTALRTDVRQQLFQELQGVRLLTRALELTLGMTEGERHPELLPPQETERAMEILKVLFNITFDSIKREVDEEDAALYRHLGTLLRHCVMLAAAGDRTEELHGHAVNLLGNLPVKCLDVLLTLEPHEGSLEFLGVNMDVIRVLLSFMEKRLHQTHRLKESVAPVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGELLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVNMFDKLSRHRVIQPMGMSPRGQLTSLQDAMCETMEGQLSSDPDSDPD", "length": 514, "header": "tr|A0ABI0P1P8-1|A0ABI0P1P8_BOVIN Computationally mapped isoform of Synembryn OS=Bos taurus OX=9913 GN=RIC8A PE=3 SV=1 CANONICAL=A0ABI0NRV0-1" }, "locus": { "chromosome": "11", "start_pos": 82878210, "end_pos": 82873544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151926.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151926.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105180.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105180.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRV0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRV0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G-protein alpha-subunit binding", "id": "GO:0001965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001965", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRV0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRV0" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRV0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 229, "end_pos": 231 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NMV3-1", "uniprot_ac": "A0ABI0NMV3", "uniprot_id": "A0ABI0NMV3_BOVIN", "mass": { "chemical_mass": 18934.0, "monoisotopic_mass": 18934.0 }, "refseq": {}, "gene_names": [ { "name": "MMGT1", "type": "recommended", "evidence": [ { "id": "A0ABI0NMV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3" } ] } ], "protein_names": [ { "name": "Membrane magnesium transporter", "type": "recommended", "evidence": [ { "id": "A0ABI0NMV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJ41", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ41#function" }, { "database": "UniProtKB", "id": "RU367002", "url": "https://www.uniprot.org/uniprotkb/RU367002#function" }, { "database": "UniProtKB", "id": "A0ABI0NMV3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3#function" }, { "database": "UniProtKB", "id": "A0ABI0P5L2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5L2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMV3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MMGT1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3", "locus": {} } ], "crossref": [ { "id": "617557", "url": "https://www.ncbi.nlm.nih.gov/gene/617557", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21181:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21181:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NJ41", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJ41-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMV3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMV3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P053", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P053", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P053-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P053-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5L2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5L2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5L2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPSLWKGLVGIGLFALAHAAFSAAQHYFPSSGIKWKRKCEFLQSSSFQDKIFRSMYYVYDRSYMRLTEKEDESLPIDIVLQTLLAFAVTCYGIVHIAGEFKDMDATSELKNKTFDTLRNHPSFYVFNHRGRVLFRPSDTTNSSNQDALSSNTSLKLRKLESLRR", "length": 165, "header": "tr|A0ABI0NMV3-1|A0ABI0NMV3_BOVIN Isoform 1 of Membrane magnesium transporter OS=Bos taurus OX=9913 GN=MMGT1 PE=3 SV=1 CANONICAL=A0ABI0NMV3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NJ41-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3/entry#A0ABI0NJ41-1", "sequence": { "sequence": "MAPSLWKGLVGIGLFALAHAAFSAAQHRSYMRLTEKEDESLPIDIVLQTLLAFAVTCYGIVHIAGEFKDMDATSELKNKTFDTLRNHPSFYVFNHRGRVLFRPSDTTNSSNQDALSSNTSLKLRKLESLRR", "length": 131, "header": "tr|A0ABI0NJ41-1|A0ABI0NMV3_BOVIN Computationally mapped isoform of Membrane magnesium transporter OS=Bos taurus OX=9913 GN=MMGT1 PE=3 SV=1 CANONICAL=A0ABI0NMV3-1" }, "locus": { "chromosome": "NKLS02002208.1", "start_pos": 8934461, "end_pos": 8925722, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147926.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147926.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104380.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104380.1" } ] } }, { "isoform_ac": "A0ABI0NMV3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3/entry#A0ABI0NMV3-1", "sequence": { "sequence": "MAPSLWKGLVGIGLFALAHAAFSAAQHYFPSSGIKWKRKCEFLQSSSFQDKIFRSMYYVYDRSYMRLTEKEDESLPIDIVLQTLLAFAVTCYGIVHIAGEFKDMDATSELKNKTFDTLRNHPSFYVFNHRGRVLFRPSDTTNSSNQDALSSNTSLKLRKLESLRR", "length": 165, "header": "tr|A0ABI0NMV3-1|A0ABI0NMV3_BOVIN Isoform 1 of Membrane magnesium transporter OS=Bos taurus OX=9913 GN=MMGT1 PE=3 SV=1 CANONICAL=A0ABI0NMV3-1" }, "locus": { "chromosome": "NKLS02002208.1", "start_pos": 8934461, "end_pos": 8925722, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147810.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147810.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106855.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106855.1" } ] } }, { "isoform_ac": "A0ABI0P053-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3/entry#A0ABI0P053-1", "sequence": { "sequence": "MHWRRKWQPTPVFLPGESQGRGSLVGCCLWGRTESDTTEVTQQQQQQQWIVLQTLLAFAVTCYGIVHIAGEFKDMDATSELKNKTFDTLRNHPSFYVFNHRGRVLFRPSDTTNSSNQDALSSNTSLKLRKLESLRR", "length": 136, "header": "tr|A0ABI0P053-1|A0ABI0P053_BOVIN Computationally mapped isoform of Membrane magnesium transporter 1 OS=Bos taurus OX=9913 GN=MMGT1 PE=4 SV=1 CANONICAL=A0ABI0NMV3-1" }, "locus": { "chromosome": "NKLS02002208.1", "start_pos": 8934461, "end_pos": 8932120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154651.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154651.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104153.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104153.1" } ] } }, { "isoform_ac": "A0ABI0P5L2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3/entry#A0ABI0P5L2-1", "sequence": { "sequence": "ISFVTYRAHEDYFPSSGIKWKRKCEFLQSSSFQDKIFRSMYYVYDRSYMRLTEKEDESLPIDIVLQTLLAFAVTCYGIVHIAGEFKDMDATSELKNKTFDTLRNHPSFYVFNHRGRVLFRPSDTTNSSNQDALSSNTSLKLRKLESLRR", "length": 149, "header": "tr|A0ABI0P5L2-1|A0ABI0P5L2_BOVIN Computationally mapped isoform of Membrane magnesium transporter OS=Bos taurus OX=9913 GN=MMGT1 PE=3 SV=1 CANONICAL=A0ABI0NMV3-1" }, "locus": { "chromosome": "NKLS02002208.1", "start_pos": 8934461, "end_pos": 8926857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140326.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140326.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107278.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107278.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "EMC complex", "id": "GO:0072546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072546", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMV3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMV3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMV3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMV3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMV3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NKC6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKC6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMG0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMG0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRG0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRG0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RREGRSLSSRKLARAGPRSRPWLLGRASSQLVGPRSHRGGAQTDNLKEPRHHPPTLGTSLQRLTHRPGGPPGAPSPERSTSARGLSSAPARGPRSSDAFPNAAGRASPEPGPRGVGPRFERAIQTENPEESFGTSLVVANSTVSNARKRPWLDRAGEDRTPPIAGAGCGEGVGDAHSLCLDLTVKSQSRPGQPWCQVQGSVDTKPFLQYDSASNKVKPLGFLGKEVNDTKAWTEISQTLVEAGKELRMVLPVIKLDENETRGPPTLQVKLCCQREAEQCSGASLHFSLNGRTALLLDTMSITWTVIDPGATGIKEEWENNQELAEYFRTISTGDCSYWLREFLKHWEKMLVPEPTESLIMAADISQSASIRLDSCIILLIITQLVLIASSS", "length": 391, "header": "tr|A0ABI0NMG0-1|A0ABI0NMG0_BOVIN Isoform 1 of MHC class I-like antigen recognition-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC100848331 PE=4 SV=1 CANONICAL=A0ABI0NMG0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NKC6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMG0/entry#A0ABI0NKC6-1", "sequence": { "sequence": "MSLARTADHLLLILLLIEARKTLGNAHSLCLDLTVKSQSRPGQPWCQVQGSVDTKPFLQYDSASNKVKPLGFLGKEVNDTKAWTEISQTLVEAGKELRMVLPVIKLDENETRGPPTLQVKLCCQREAEQCSGASLHFSLNGRTALLLDTMSITWTVIDPGATGIKEEWENNQELAEYFRTISTGDCSYWLREFLKHWEKMLVPEPTESLIMAADISQSASIRLDSCIILLIITQLVLIASSS", "length": 242, "header": "tr|A0ABI0NKC6-1|A0ABI0NMG0_BOVIN Computationally mapped isoform of MHC class I-like antigen recognition-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC100848331 PE=4 SV=1 CANONICAL=A0ABI0NMG0-1" }, "locus": { "chromosome": "9", "start_pos": 87535125, "end_pos": 87532534, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154827.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154827.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104818.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104818.1" } ] } }, { "isoform_ac": "A0ABI0NMG0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMG0/entry#A0ABI0NMG0-1", "sequence": { "sequence": "RREGRSLSSRKLARAGPRSRPWLLGRASSQLVGPRSHRGGAQTDNLKEPRHHPPTLGTSLQRLTHRPGGPPGAPSPERSTSARGLSSAPARGPRSSDAFPNAAGRASPEPGPRGVGPRFERAIQTENPEESFGTSLVVANSTVSNARKRPWLDRAGEDRTPPIAGAGCGEGVGDAHSLCLDLTVKSQSRPGQPWCQVQGSVDTKPFLQYDSASNKVKPLGFLGKEVNDTKAWTEISQTLVEAGKELRMVLPVIKLDENETRGPPTLQVKLCCQREAEQCSGASLHFSLNGRTALLLDTMSITWTVIDPGATGIKEEWENNQELAEYFRTISTGDCSYWLREFLKHWEKMLVPEPTESLIMAADISQSASIRLDSCIILLIITQLVLIASSS", "length": 391, "header": "tr|A0ABI0NMG0-1|A0ABI0NMG0_BOVIN Isoform 1 of MHC class I-like antigen recognition-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC100848331 PE=4 SV=1 CANONICAL=A0ABI0NMG0-1" }, "locus": { "chromosome": "9", "start_pos": 87535125, "end_pos": 87531057, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148973.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148973.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106307.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106307.1" } ] } }, { "isoform_ac": "A0ABI0NRG0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMG0/entry#A0ABI0NRG0-1", "sequence": { "sequence": "MRESDLGWTGQARTAPRRSQEPDAEKEWAGFLSLGLKTLGGARRQRYRHTPGYLLLVTLLKLQGGMSLARTADHLLLILLLIEARKTLGNAHSLCLDLTVKSQSRPGQPWCQVQGSVDTKPFLQYDSASNKVKPLGFLGKEVNDTKAWTEISQTLVEAGKELRMVLPVIKLDENETRGPPTLQVKLCCQREAEQCSGASLHFSLNGRTALLLDTMSITWTVIDPGATGIKEEWENNQELAEYFRTISTGDCSYWLREFLKHWEKMLVPEPTESLIMAADISQSASIRLDSCIILLIITQLVLIASSS", "length": 307, "header": "tr|A0ABI0NRG0-1|A0ABI0NRG0_BOVIN Computationally mapped isoform of MHC class I-like antigen recognition-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC100848331 PE=4 SV=1 CANONICAL=A0ABI0NMG0-1" }, "locus": { "chromosome": "9", "start_pos": 87535125, "end_pos": 87531490, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153297.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153297.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105127.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105127.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "natural killer cell lectin-like receptor binding", "id": "GO:0046703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046703", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMG0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMG0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMG0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMG0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NMG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMG0" }, { "id": "PF00129", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00129" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MHC class I-like antigen recognition-like", "eco_id": "ECO_0000259", "start_pos": 175, "end_pos": 348, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 227, "end_pos": 229 }, { "start_pos": 258, "end_pos": 260 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NNF1-1", "uniprot_ac": "A0ABI0NNF1", "uniprot_id": "A0ABI0NNF1_BOVIN", "mass": { "chemical_mass": 206004.0, "monoisotopic_mass": 206004.0 }, "refseq": {}, "gene_names": [ { "name": "WDR90", "type": "recommended", "evidence": [ { "id": "A0ABI0NNF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNF1" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 90", "type": "recommended", "evidence": [ { "id": "A0ABI0NNF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNF1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Microtubule-binding protein that plays a crucial role in ensuring inner core protein localization within the centriole core, as well as in maintaining the microtubule wall integrity and the overall centriole roundness and stability. Required for efficient primary cilium formation.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKE6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKE6#function" }, { "database": "UniProtKB", "id": "ARBA00060089", "url": "https://www.uniprot.org/uniprotkb/ARBA00060089#function" }, { "database": "UniProtKB", "id": "A0ABI0NNF1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNF1#function" }, { "database": "UniProtKB", "id": "A0ABI0P1K0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1K0#function" }, { "database": "UniProtKB", "id": "A0ABI0P3M2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3M2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNF1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNF1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "WDR90", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNF1", "locus": {} } ], "crossref": [ { "id": "101902709", "url": "https://www.ncbi.nlm.nih.gov/gene/101902709", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:101902709", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101902709", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR13720", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13720", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13720:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13720:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23342", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23342", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NKE6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKE6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNF1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNF1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1K0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1K0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1K0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3M2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3M2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3M2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARVWQQPFLNVFRHFKVDEWKRSTKEGDVAAVTDKTLKCTVYRVRGSVSASNYIQLPKTSTQSLGLTGRYLYVLFRPLPTKHFVIHLDVSTEDSQVIRVSFSNLFKEFKSTATWLQFPFICEAGTPREGTVQMRHEWDTGMVWERRPVRRLRGRSGWGPRGCGRETGNRPRTQCCGLVGERVGADFGTSPAYLPGVASPGARWTCLQLDLHDILLVYLHRCYSHLKGVRLCASMLVRNLYTSDLCFNPAVTVAEARRAKLPVTPIPREMAFPVPKGESWHDRYVHIRFPSGSSHVPSKLVQKSGFPPEAVLVGHVPRLLPSPVACSKPARDSRALMVQKHDPEASRWAPSMPRPLPEVSMSCERSEVSRVAGPGGCTQEPSAWAEATDEHAAGDGLHVSAGQPTVEPAAPEDAAPHESPGRKQSLPEAALGKKRFQQRSFLPDPILRLKGVIGFGGHSTKWALWTPDGAAVVYPCHAVVVVLHVETREQRLFLGHTDKVSALALDGSGSLLASAQARPHSMLRLWDFQTGSCLALFRSPVHTICSLSFSNSGELLCGVGKDRHGRTTVLVWGVAQLGRGGEAIILAQAHSDADVQVFRVAFFDEARMASCGRGNVRLWRLRGGVLRSCAVDLGEHHALEFTDLAFGPAQDGHTLYVCSRSGHILEIDHQRMAVRHARRLLPLQTPRDPLAQKQTFSSGPGIAISSLGVSRSACAVGSEDGYLRLWPLDFSSVLLEAEHEGPVTSVCVSPGGLRVLSTTSSGHLGFLDVPSQEYHMLVRSHTAPVLALAIERSRGQLATVSQDRTVRVWDLATLQQLYDFMSPAEAPRAVAFHPTQPTFFCGFSSGAVRSFSLESAEALVEHRCHRGAITSLAASPDGRFLFSACSRGALAQYHSGAPRCRVLRVAANVVCQEACPSSSIMVVSRDSRLLAFVGPSKYTVSVVDTASLDELLKVDVSALDLAGSCLDSAVALCFGPSPPSHLLVSMSSNMITVLDARSGRVVRQLSCGHPAACASLSLSADGRFLLTAAERAVRLWDYATQAGLSCQVYIGHSEPVQAVAFTPDQQQLLSVGDAIFLWDILVPREGWSPGSVQGAPRPPLTCEAGPGAGELEGVASGARAPPRQVSVSPPALPPEPGLCAEPPEGFDGALFPSDESHGPEDLHQASGPSVLVQKEAGRADDGACGVTGGPWDLGRRPHPCGWPRACSTVGARARTLARPDSYRHFTARYKASSLAQGLSLPPAGDEWLRLKAVVGYNGNGRTNLVWSPDTGFFAYTCGCLVVVEDLHSGAQQHWLGHPEEISTLALSHDAQVLVSASSGSGTASRCQIRLWDVPRGSCRQLLSHHDSAVQALAFSPDDRLLVTLGDCGDGTLALWSTATCELLSSTRLPEPVHSMAFSPWHASELACVGRGVLTLQLLWGQAGDVSLQANREPVPEEAGGCELSSLCYGAPPLLYCGSSEGQVSVWDTRAGRCFLAWEADDGEIGVLLCSGTWLVSGSNTRRLRLWAVGAVSELWRRGSGARSSSVFLERELTLDGAVVSAVFHDSMDMGVVGTTAGTLWYVSWAEGTSTRLISGHRSKVNDVAFSPNESHCATCSDDGSVRVWCVASTELLIQFQVLSQSCLCLAWSPPSCGRPEEEHVAAGYSDGTLRVFSIARSAVELKMCPHAAALRALAFSADGQTIISGDKDGLVAVSRLRTGMTFRVLSDHRGAPICTLQSTRKECGDFGAEGTDLWLAASGDQRVSVWASDWLRDHCELVDWLSFPAPGLTEVRVPAAPWAQCPRLPPCTVPPQVPGCLPPSLAAFCPWDPAVLVCAGLGVYPEVVFYSLRQKQVVEKIPLPFFAVSMSLCPGAHLVAIGFSERMVRLLDCASGAVQDFAGHDDSVQLCRFAPSAQLLFTAAHSEILVWEVTGR", "length": 1912, "header": "tr|A0ABI0NNF1-1|A0ABI0NNF1_BOVIN Isoform 1 of WD repeat-containing protein 90 OS=Bos taurus OX=9913 GN=WDR90 PE=3 SV=1 CANONICAL=A0ABI0NNF1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NKE6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNF1/entry#A0ABI0NKE6-1", "sequence": { "sequence": "MARVWQQPFLNVFRHFKVDEWKRSTKEGDVAAVTDKTLKCTVYRVRGSVSASNYIQLPKTSTQSLGLTGRYLYVLFRPLPTKHFVIHLDVSTEDSQVIRVSFSNLFKEFKSTATWLQFPFICEAGTPREGVASPGARWTCLQLDLHDILLVYLHRCYSHLKGVRLCASMLVRNLYTSDLCFNPAVTVAEARRAKLPVTPIPREMAFPVPKGESWHDRYVHIRFPSGSSHVPSKLVQKSGFPPEAVLVGHVPRLLPSPVACSKPARDSRALMVQKHDPEASRWAPSMPRPLPEVSMSCERSEVSRVAGPGGCTQEPSAWAEATDEHAAGDGLHVSAGQPTVEPAAPEDAAPHESPGRKQSLPEAALGKKRFQQRSFLPDPILRLKGVIGFGGHSTKWALWTPDGAAVVYPCHAVVVVLHVETREQRLFLGHTDKVSALALDGSGSLLASAQARPHSMLRLWDFQTGSCLALFRSPVHTICSLSFSNSGELLCGVGKDRHGRTTVLVWGVAQLGRGGEAIILAQAHSDADVQVFRVAFFDEARMASCGRGNVRLWRLRGGVLRSCAVDLGEHHALEFTDLAFGPAQDGHTLYVCSRSGHILEIDHQRMAVRHARRLLPLQTPRDPLAQKQTFSSGPGIAISSLGVSRSACAVGSEDGYLRLWPLDFSSVLLEAEHEGPVTSVCVSPGGLRVLSTTSSGHLGFLDVPSQEYHMLVRSHTAPVLALAIERSRGQLATVSQDRTVRVWDLATLQQLYDFMSPAEAPRAVAFHPTQPTFFCGFSSGAVRSFSLESAEALVEHRCHRGAITSLAASPDGRFLFSACSRGALAQYHSGAPRCRVLRVAANVVCQEACPSSSIMVVSRDSRLLAFVGPSKYTVSVVDTASLDELLKVDVSALDLAGSCLDSAVALCFGPSPPSHLLVSMSSNMITVLDARSGRVVRQLSCGHPAACASLSLSADGRFLLTAAERAVRLWDYATQAGLSCQVYIGHSEPVQAVAFTPDQQQLLSVGDAIFLWDILVPREGWSPGSVQGAPRPPLTCEAGPGAGELEGVASGARAPPRQVSVSPPALPPEPGLCAEPPEGFDGALFPSDESHGPEDLHQASGPSVLVQKEAGRADDGACGVTGGPWDLGRRPHPCGWPRACSTVGARARTLARPDSYRHFTARYKASSLAQGLSLPPAGDEWLRLKAVVGYNGNGRTNLVWSPDTGFFAYTCGCLVVVEDLHSGAQQHWLGHPEEISTLALSHDAQVLVSASSGSGTASRCQIRLWDVPRGSCRQLLSHHDSAVQALAFSPDDRLLVTLGDCGDGTLALWSTATCELLSSTRLPEPVHSMAFSPWHASELACVGRGVLTLQLLWGQAGDVSLQANREPVPEEAGGCELSSLCYGAPPLLYCGSSEGQVSVWDTRAGRCFLAWEADDGEIGVLLCSGTWLVSGSNTRRLRLWAVGAVSELWRRGSGARSSSVFLERELTLDGAVVSAVFHDSMDMGVVGTTAGTLWYVSWAEGTSTRLISGHRSKVNDVAFSPNESHCATCSDDGSVRVWCVASTELLIQFQVLSQSCLCLAWSPPSCGRPEEEHVAAGYSDGTLRVFSIARSAVELKMCPHAAALRALAFSADGQTIISGDKDGLVAVSRLRTGMTFRVLSDHRGAPICTLQSTRKECGDFGAEGTDLWLAASGDQRVSVWASDWLRDHCELVDWLSFPAPGLTEVPGCLPPSLAAFCPWDPAVLVCAGLGVYPEVVFYSLRQKQVVEKIPLPFFAVSMSLCPGAHLVAIGFSERMVRLLDCASGAVQDFAGHDDSVQLCRFAPSAQLLFTAAHSEILVWEVTGR", "length": 1824, "header": "tr|A0ABI0NKE6-1|A0ABI0NNF1_BOVIN Computationally mapped isoform of WD repeat-containing protein 90 OS=Bos taurus OX=9913 GN=WDR90 PE=3 SV=1 CANONICAL=A0ABI0NNF1-1" }, "locus": { "chromosome": "25", "start_pos": 572992, "end_pos": 558958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137840.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137840.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105160.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105160.1" } ] } }, { "isoform_ac": "A0ABI0NNF1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNF1/entry#A0ABI0NNF1-1", "sequence": { "sequence": "MARVWQQPFLNVFRHFKVDEWKRSTKEGDVAAVTDKTLKCTVYRVRGSVSASNYIQLPKTSTQSLGLTGRYLYVLFRPLPTKHFVIHLDVSTEDSQVIRVSFSNLFKEFKSTATWLQFPFICEAGTPREGTVQMRHEWDTGMVWERRPVRRLRGRSGWGPRGCGRETGNRPRTQCCGLVGERVGADFGTSPAYLPGVASPGARWTCLQLDLHDILLVYLHRCYSHLKGVRLCASMLVRNLYTSDLCFNPAVTVAEARRAKLPVTPIPREMAFPVPKGESWHDRYVHIRFPSGSSHVPSKLVQKSGFPPEAVLVGHVPRLLPSPVACSKPARDSRALMVQKHDPEASRWAPSMPRPLPEVSMSCERSEVSRVAGPGGCTQEPSAWAEATDEHAAGDGLHVSAGQPTVEPAAPEDAAPHESPGRKQSLPEAALGKKRFQQRSFLPDPILRLKGVIGFGGHSTKWALWTPDGAAVVYPCHAVVVVLHVETREQRLFLGHTDKVSALALDGSGSLLASAQARPHSMLRLWDFQTGSCLALFRSPVHTICSLSFSNSGELLCGVGKDRHGRTTVLVWGVAQLGRGGEAIILAQAHSDADVQVFRVAFFDEARMASCGRGNVRLWRLRGGVLRSCAVDLGEHHALEFTDLAFGPAQDGHTLYVCSRSGHILEIDHQRMAVRHARRLLPLQTPRDPLAQKQTFSSGPGIAISSLGVSRSACAVGSEDGYLRLWPLDFSSVLLEAEHEGPVTSVCVSPGGLRVLSTTSSGHLGFLDVPSQEYHMLVRSHTAPVLALAIERSRGQLATVSQDRTVRVWDLATLQQLYDFMSPAEAPRAVAFHPTQPTFFCGFSSGAVRSFSLESAEALVEHRCHRGAITSLAASPDGRFLFSACSRGALAQYHSGAPRCRVLRVAANVVCQEACPSSSIMVVSRDSRLLAFVGPSKYTVSVVDTASLDELLKVDVSALDLAGSCLDSAVALCFGPSPPSHLLVSMSSNMITVLDARSGRVVRQLSCGHPAACASLSLSADGRFLLTAAERAVRLWDYATQAGLSCQVYIGHSEPVQAVAFTPDQQQLLSVGDAIFLWDILVPREGWSPGSVQGAPRPPLTCEAGPGAGELEGVASGARAPPRQVSVSPPALPPEPGLCAEPPEGFDGALFPSDESHGPEDLHQASGPSVLVQKEAGRADDGACGVTGGPWDLGRRPHPCGWPRACSTVGARARTLARPDSYRHFTARYKASSLAQGLSLPPAGDEWLRLKAVVGYNGNGRTNLVWSPDTGFFAYTCGCLVVVEDLHSGAQQHWLGHPEEISTLALSHDAQVLVSASSGSGTASRCQIRLWDVPRGSCRQLLSHHDSAVQALAFSPDDRLLVTLGDCGDGTLALWSTATCELLSSTRLPEPVHSMAFSPWHASELACVGRGVLTLQLLWGQAGDVSLQANREPVPEEAGGCELSSLCYGAPPLLYCGSSEGQVSVWDTRAGRCFLAWEADDGEIGVLLCSGTWLVSGSNTRRLRLWAVGAVSELWRRGSGARSSSVFLERELTLDGAVVSAVFHDSMDMGVVGTTAGTLWYVSWAEGTSTRLISGHRSKVNDVAFSPNESHCATCSDDGSVRVWCVASTELLIQFQVLSQSCLCLAWSPPSCGRPEEEHVAAGYSDGTLRVFSIARSAVELKMCPHAAALRALAFSADGQTIISGDKDGLVAVSRLRTGMTFRVLSDHRGAPICTLQSTRKECGDFGAEGTDLWLAASGDQRVSVWASDWLRDHCELVDWLSFPAPGLTEVRVPAAPWAQCPRLPPCTVPPQVPGCLPPSLAAFCPWDPAVLVCAGLGVYPEVVFYSLRQKQVVEKIPLPFFAVSMSLCPGAHLVAIGFSERMVRLLDCASGAVQDFAGHDDSVQLCRFAPSAQLLFTAAHSEILVWEVTGR", "length": 1912, "header": "tr|A0ABI0NNF1-1|A0ABI0NNF1_BOVIN Isoform 1 of WD repeat-containing protein 90 OS=Bos taurus OX=9913 GN=WDR90 PE=3 SV=1 CANONICAL=A0ABI0NNF1-1" }, "locus": { "chromosome": "25", "start_pos": 572992, "end_pos": 558958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150094.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150094.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104243.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104243.1" } ] } }, { "isoform_ac": "A0ABI0P1K0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNF1/entry#A0ABI0P1K0-1", "sequence": { "sequence": "MARVWQQPFLNVFRHFKVDEWKRSTKEGDVAAVTDKTLKCTVYRVRGSVSASNYIQLPKTSTQSLGLTGRYLYVLFRPLPTKHFVIHLDVSTEDSQVIRVSFSNLFKEFKSTATWLQFPFICEAGTPREGVASPGARWTCLQLDLHDILLVYLHRCYSHLKGVRLCASMLVRNLYTSDLCFNPAVTVAEARRAKLPVTPIPREMAFPVPKGESWHDRYVHIRFPSGSSHVPSKLVQKSGFPPEAVLVGHVPRLLPSPVACSKPARDSRALMVQKHDPEASRWAPSMPRPLPEVSMSCERSEVSRVAGPGGCTQEPSAWAEATDEHAAGDGLHVSAGQPTVEPAAPEDAAPHESPGRKQSLPEAALGKKRFQQRSFLPDPILRLKGVIGFGGHSTKWALWTPDGAAVVYPCHAVVVVLHVETREQRLFLGHTDKVSALALDGSGSLLASAQARPHSMLRLWDFQTGSCLALFRSPVHTICSLSFSNSGELLCGVGKDRHGRTTVLVWGVAQLGRGGEAIILAQAHSDADVQVFRVAFFDEARMASCGRGNVRLWRLRGGVLRSCAVDLGEHHALEFTDLAFGPAQDGHTLYVCSRSGHILEIDHQRMAVRHARRLLPLQTPRDPLAQKQTFSSGPGIAISSLGVSRSACAVGSEDGYLRLWPLDFSSVLLEAEHEGPVTSVCVSPGGLRVLSTTSSGHLGFLDVPSQEYHMLVRSHTAPVLALAIERSRGQLATVSQDRTVRVWDLATLQQLYDFMSPAEAPRAVAFHPTQPTFFCGFSSGAVRSFSLESAEALVEHRCHRGAITSLAASPDGRFLFSACSRGALAQYHSGAPRCRVLRVAANVVCQEACPSSSIMVVSRDSRLLAFVGPSKYTVSVVDTASLDELLKVDVSALDLAGSCLDSAVALCFGPSPPSHLLVSMSSNMITVLDARSGRVVRQLSCGHPAACASLSLSADGRFLLTAAERAVRLWDYATQAGLSCQVYIGHSEPVQAVAFTPDQQQLLSVGDAIFLWDILVPREGWSPGSVQGAPRPPLTCEAGALFPSDESHGPEDLHQASGPSVLVQKEAGRADDGACGVTGGPWDLGRRPHPCGWPRACSTVGARARTLARPDSYRHFTARYKASSLAQGLSLPPAGDEWLRLKAVVGYNGNGRTNLVWSPDTGFFAYTCGCLVVVEDLHSGAQQHWLGHPEEISTLALSHDAQVLVSASSGSGTASRCQIRLWDVPRGSCRQLLSHHDSAVQALAFSPDDRLLVTLGDCGDGTLALWSTATCELLSSTRLPEPVHSMAFSPWHASELACVGRGVLTLQLLWGQAGDVSLQANREPVPEEAGGCELSSLCYGAPPLLYCGSSEGQVSVWDTRAGRCFLAWEADDGEIGVLLCSGTWLVSGSNTRRLRLWAVGAVSELWRRGSGARSSSVFLERELTLDGAVVSAVFHDSMDMGVVGTTAGTLWYVSWAEGTSTRLISGHRSKVNDVAFSPNESHCATCSDDGSVRVWCVASTELLIQFQVLSQSCLCLAWSPPSCGRPEEEHVAAGYSDGTLRVFSIARSAVELKMCPHAAALRALAFSADGQTIISGDKDGLVAVSRLRTGMTFRVLSDHRGAPICTLQSTRKECGDFGAEGTDLWLAASGDQRVSVWASDWLRDHCELVDWLSFPAPGLTEVRVPAAPWAQCPRLPPCTVPPQVPGCLPPSLAAFCPWDPAVLVCAGLGVYPEVVFYSLRQKQVVEKIPLPFFAVSMSLCPGAHLVAIGFSERMVRLLDCASGAVQDFAGHDDSVQLCRFAPSAQLLFTAAHSEILVWEVTGR", "length": 1803, "header": "tr|A0ABI0P1K0-1|A0ABI0P1K0_BOVIN Computationally mapped isoform of WD repeat-containing protein 90 OS=Bos taurus OX=9913 GN=WDR90 PE=3 SV=1 CANONICAL=A0ABI0NNF1-1" }, "locus": { "chromosome": "25", "start_pos": 572992, "end_pos": 558958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143711.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143711.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104267.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104267.1" } ] } }, { "isoform_ac": "A0ABI0P3M2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNF1/entry#A0ABI0P3M2-1", "sequence": { "sequence": "MARVWQQPFLNVFRHFKVDEWKRSTKEGDVAAVTDKTLKCTVYRVRGSVSASNYIQLPKTSTQSLGLTGRYLYVLFRPLPTKHFVIHLDVSTEDSQVIRVSFSNLFKEFKSTATWLQFPFICEAGTPREGVASPGARWTCLQLDLHDILLVYLHRCYSHLKGVRLCASMLVRNLYTSDLCFNPAVTVAEARRAKLPVTPIPREMAFPVPKGESWHDRYVHIRFPSGSSHVPSKLVQKSGFPPEAVLVGHVPRLLPSPVACSKPARDSRALMVQKHDPEASRWAPSMPRPLPEVSMSCERSEVSRVAGPGGCTQEPSAWAEATDEHAAGDGLHVSAGQPTVEPAAPEDAAPHESPGRKQSLPEAALGKKRFQQRSFLPDPILRLKGVIGFGGHSTKWALWTPDGAAVVYPCHAVVVVLHVETREQRLFLGHTDKVSALALDGSGSLLASAQARPHSMLRLWDFQTGSCLALFRSPVHTICSLSFSNSGELLCGVGKDRHGRTTVLVWGVAQLGRGGEAIILAQAHSDADVQVFRVAFFDEARMASCGRGNVRLWRLRGGVLRSCAVDLGEHHALEFTDLAFGPAQDGHTLYVCSRSGHILEIDHQRMAVRHARRLLPLQTPRDPLAQKQTFSSGPGIAISSLGVSRSACAVGSEDGYLRLWPLDFSSVLLEAEHEGPVTSVCVSPGGLRVLSTTSSGHLGFLDVPSQEYHMLVRSHTAPVLALAIERSRGQLATVSQDRTVRVWDLATLQQLYDFMSPAEAPRAVAFHPTQPTFFCGFSSGAVRSFSLESAEALVEHRCHRGAITSLAASPDGRFLFSACSRGALAQYHSGAPRCRVLRVAANVVCQEACPSSSIMVVSRDSRLLAFVGPSKYTVSVVDTASLDELLKVDVSALDLAGSCLDSAVALCFGPSPPSHLLVSMSSNMITVLDARSGRVVRQLSCGHPAACASLSLSADGRFLLTAAERAVRLWDYATQAGLSCQVYIGHSEPVQAVAFTPDQQQLLSVGDAIFLWDILVPREGWSPGSVQGAPRPPLTCEAGPGAGELEGVASGARAPPRQVSVSPPALPPEPGLCAEPPEGFDGALFPSDESHGPEDLHQASGPSVLVQKEAGRADDGACGVTGGPWDLGRRPHPCGWPRACSTVGARARTLARPDSYRHFTARYKASSLAQGLSLPPAGDEWLRLKAVVGYNGNGRTNLVWSPDTGFFAYTCGCLVVVEDLHSGAQQHWLGHPEEISTLALSHDAQVLVSASSGSGTASRCQIRLWDVPRGSCRQLLSHHDSAVQALAFSPDDRLLVTLGDCGDGTLALWSTATCELLSSTRLPEPVHSMAFSPWHASELACVGRGVLTLQLLWGQAGDVSLQANREPVPEEAGGCELSSLCYGAPPLLYCGSSEGQVSVWDTRAGRCFLAWEADDGEIGVLLCSGTWLVSGSNTRRLRLWAVGAVSELWRRGSGARSSSVFLERELTLDGAVVSAVFHDSMDMGVVGTTAGTLWYVSWAEGTSTRLISGHRSKVNDVAFSPNESHCATCSDDGSVRVWCVASTELLIQFQVLSQSCLCLAWSPPSCGRPEEEHVAAGYSDGTLRVFSIARSAVELKMCPHAAALRALAFSADGQTIISGDKDGLVAVSRLRTGMTFRVLSDHRGAPICTLQSTRKECGDFGAEGTDLWLAASGDQRVSVWASDWLRDHCELVDWLSFPAPGLTEVRVPAAPWAQCPRLPPCTVPPQVPGCLPPSLAAFCPWDPAVLVCAGLGVYPEVVFYSLRQKQVVEKIPLPFFAVSMSLCPGAHLVAIGFSERMVRLLDCASGAVQDFAGHDDSVQLCRFAPSAQLLFTAAHSEILVWEVTGR", "length": 1846, "header": "tr|A0ABI0P3M2-1|A0ABI0P3M2_BOVIN Computationally mapped isoform of WD repeat-containing protein 90 OS=Bos taurus OX=9913 GN=WDR90 PE=3 SV=1 CANONICAL=A0ABI0NNF1-1" }, "locus": { "chromosome": "25", "start_pos": 572992, "end_pos": 558958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136462.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136462.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105360.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105360.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 252, "start_aa": "Thr", "end_pos": 252, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr252", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:101902709", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101902709", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNF1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1588, "end_pos": 1590, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NMR5-1", "uniprot_ac": "A0ABI0NMR5", "uniprot_id": "A0ABI0NMR5_BOVIN", "mass": { "chemical_mass": 36846.0, "monoisotopic_mass": 36846.0 }, "refseq": {}, "gene_names": [ { "name": "LOC132344513", "type": "recommended", "evidence": [ { "id": "A0ABI0NMR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMR5" } ] } ], "protein_names": [ { "name": "Testis-specific Y-encoded 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"PTHR11875", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11875", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00956", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00956", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NLE7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLE7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMR5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMR5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESETGPEEGGSTPGSWILVVSPGLHEGGALGPTSSVWAAEAMQAAGGAPGEEAALFWVEAVEEGAAVEEGEVAGLGQEFQLLVLDVMEEVEVVAYEEQEQVSSEEHVHDHPRPGALSDRPALEALAALQLELEPVNKKAERAHARLKHKTSQRRKVHLEHRSAIIQGIRGFWVEVFMNHPQMSVLMSKQDADMLHFMTNLEVEEFRHPTRHCKITLSFRRNRYFQNEVIVKEYLMKVTGYHASHSTPVQWHQGFEWKAYRRRHHDSSVNFFNWFFDHNFTGSDWIAEIIIRDLWPNPLQYYVRRKAAPQKVPGGREEPDPPSF", "length": 324, "header": "tr|A0ABI0NMR5-1|A0ABI0NMR5_BOVIN Isoform 1 of Testis-specific Y-encoded protein 3-like OS=Bos taurus OX=9913 GN=LOC132344513 PE=3 SV=1 CANONICAL=A0ABI0NMR5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NLE7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMR5/entry#A0ABI0NLE7-1", "sequence": { "sequence": "MESETGPEEGGSTPGSWILVVSPGLHEGGALGPTSSVWAAEAMQAAGGAPGEEAALFWVEAVEEGAAVEEGEVAGLGQEFQLLVLDVMEEVEVVAYEEQEQVSSEEHVHDHPRPGALSDRPALEALAALQLELEPVNKKAERAHARLKHKTSQRRKVHLEHRSAIIQGIRGFWVEVVSLGVVLVEEFRHPTRHCKITLSFRRNRYFQNEVIVKEYLMKVTGYHASHSTPVQWHQGFEWKAYRRRHHDSSVNFFNWFFDHNFTGSDWIAEIIIRDLWPNPLQYYVRRKAAPQKVPGGREEPDPPSF", "length": 305, "header": "tr|A0ABI0NLE7-1|A0ABI0NMR5_BOVIN Computationally mapped isoform of Testis-specific Y-encoded protein 3-like OS=Bos taurus OX=9913 GN=LOC132344513 PE=3 SV=1 CANONICAL=A0ABI0NMR5-1" }, "locus": { "chromosome": "Y", "start_pos": 19970633, "end_pos": 19967405, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143186.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143186.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105870.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105870.1" } ] } }, { "isoform_ac": "A0ABI0NMR5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMR5/entry#A0ABI0NMR5-1", "sequence": { "sequence": "MESETGPEEGGSTPGSWILVVSPGLHEGGALGPTSSVWAAEAMQAAGGAPGEEAALFWVEAVEEGAAVEEGEVAGLGQEFQLLVLDVMEEVEVVAYEEQEQVSSEEHVHDHPRPGALSDRPALEALAALQLELEPVNKKAERAHARLKHKTSQRRKVHLEHRSAIIQGIRGFWVEVFMNHPQMSVLMSKQDADMLHFMTNLEVEEFRHPTRHCKITLSFRRNRYFQNEVIVKEYLMKVTGYHASHSTPVQWHQGFEWKAYRRRHHDSSVNFFNWFFDHNFTGSDWIAEIIIRDLWPNPLQYYVRRKAAPQKVPGGREEPDPPSF", "length": 324, "header": "tr|A0ABI0NMR5-1|A0ABI0NMR5_BOVIN Isoform 1 of Testis-specific Y-encoded protein 3-like OS=Bos taurus OX=9913 GN=LOC132344513 PE=3 SV=1 CANONICAL=A0ABI0NMR5-1" }, "locus": { "chromosome": "Y", "start_pos": 19970633, "end_pos": 19967405, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150180.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150180.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106803.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106803.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMR5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMR5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 34 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 279, "end_pos": 281 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": 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"count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"https://www.uniprot.org/uniprotkb/A0ABI0P2S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2S2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAAAASASEAEAEPKAGPEAEGEQDEAKAARARRKVLSRAVAAATYKTMGPEWDQQEEGVSESDGDEEYAMASSAESSPGEYEWGYDEEEKNQLEIERLEEQLSINVYDYNCHVDLIRLLRLEGELTKVRMARQKMSEIFPLTEELWLEWLHDEISMAMDGLDREHVYDLFERAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLAIWEAYREFESAIVEAARLEKVHSLFRRQLAIPLYDMEATFAEYEEWSEDPIPESVIQSYNKALQQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSAHSRAVRNCPWTVALWSRYLLALERHGVEHRVISVTFEKALSAGFIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRSAFARALEYLKQEVEERFSESGDPSCLIMQNWARIEARLCNNMQKARELWDSIMTRGNAKFANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGTLEDWDIAVQKTETRLARVNEQRIKAAEKEAALAQQEEEKVEQRKRARAEKKALKKKKKTRGADKHRADEDDEKEWGDDEEEQPSKRRRVENSVPPAGEAEPGSEADLSGSSAPAATESPSELKEVRVGARRRDVPKVPHDSSKDGVTVFVSNLPYGLGEPAATLRPLFEACGDVVEVRPIFSNRGDFRGYCYVEFREEAAALQALQLDRQSVEGRPMFVSPCVDKSKNPDFKVFRYSTALEKHKLFVSGLPFSCTKEELEEICKAHGTVKDIRLVTNRAGKPKGLAYVEYENESQASQAVLKMDGMTIRENVIKVAISNPPQRKVPEKPEARKAPGSALLPRQVYGARGKGRTQLSLLPRALQRPSAATAQAENGPATPATTEAPKMSNADFAKLLLRKKLLCLLYK", "length": 965, "header": "tr|A0ABI0NTJ2-1|A0ABI0NTJ2_BOVIN Isoform 1 of Spliceosome associated factor 3, U4/U6 recycling protein OS=Bos taurus OX=9913 GN=SART3 PE=4 SV=1 CANONICAL=A0ABI0NTJ2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NLH5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTJ2/entry#A0ABI0NLH5-1", "sequence": { "sequence": "MATAAAASASEAEAEPKAGPEAEGEQDEAKAARARRKVLSRAVAAATYKTMGPEWDQQEEGVSESDGDEEYAMASSAESSPGEYEWGYDEEEKNQLEIERLEEQLSINVYDYNCHVDLIRLLRLEGELTKVRMARQKMSEIFPLTEELWLEWLHDEISMAMDGLDREHVYDLFERAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLAIWEAYREFESAIVEAARLEKVHSLFRRQLAIPLYDMEATFAEYEEWSEDPIPESVIQSYNKALQQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSAHSRAVRNCPWTVALWSRYLLALERHGVEHRVISDSSKELEELRSAFARALEYLKQEVEERFSESGDPSCLIMQNWARIEARLCNNMQKARELWDSIMTRGNAKFANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGTLEDWDIAVQKTETRLARVNEQRIKAAEKEAALAQQEEEKVEQRKRARAEKKALKKKKKTRGADKHRADEDDEKEWGDDEEEQPSKRRRVENSVPPAGEAEPGSEADLSGSSAPAATESPSELKEVRVGARRRDVPKVPHDSSKDGVTVFVSNLPYGLGEPAATLRPLFEACGDVVEVRPIFSNRGDFRGYCYVEFREEAAALQALQLDRQSVEGRPMFVSPCVDKSKNPDFKVFRYSTALEKHKLFVSGLPFSCTKEELEEICKAHGTVKDIRLVTNRAGKPKGLAYVEYENESQASQAVLKMDGMTIRENVIKVAISNPPQRKVPEKPEARKAPGSALLPRQVYGARGKGRTQLSLLPRALQRPSAATAQAENGPATPATTEAPKMSNADFAKLLLRK", "length": 921, "header": "tr|A0ABI0NLH5-1|A0ABI0NTJ2_BOVIN Computationally mapped isoform of Spliceosome associated factor 3, U4/U6 recycling protein OS=Bos taurus OX=9913 GN=SART3 PE=4 SV=1 CANONICAL=A0ABI0NTJ2-1" }, "locus": { "chromosome": "17", "start_pos": 64404864, "end_pos": 64364567, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137552.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137552.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105922.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105922.1" } ] } }, { "isoform_ac": "A0ABI0NTJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTJ2/entry#A0ABI0NTJ2-1", "sequence": { "sequence": "MATAAAASASEAEAEPKAGPEAEGEQDEAKAARARRKVLSRAVAAATYKTMGPEWDQQEEGVSESDGDEEYAMASSAESSPGEYEWGYDEEEKNQLEIERLEEQLSINVYDYNCHVDLIRLLRLEGELTKVRMARQKMSEIFPLTEELWLEWLHDEISMAMDGLDREHVYDLFERAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLAIWEAYREFESAIVEAARLEKVHSLFRRQLAIPLYDMEATFAEYEEWSEDPIPESVIQSYNKALQQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSAHSRAVRNCPWTVALWSRYLLALERHGVEHRVISVTFEKALSAGFIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRSAFARALEYLKQEVEERFSESGDPSCLIMQNWARIEARLCNNMQKARELWDSIMTRGNAKFANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGTLEDWDIAVQKTETRLARVNEQRIKAAEKEAALAQQEEEKVEQRKRARAEKKALKKKKKTRGADKHRADEDDEKEWGDDEEEQPSKRRRVENSVPPAGEAEPGSEADLSGSSAPAATESPSELKEVRVGARRRDVPKVPHDSSKDGVTVFVSNLPYGLGEPAATLRPLFEACGDVVEVRPIFSNRGDFRGYCYVEFREEAAALQALQLDRQSVEGRPMFVSPCVDKSKNPDFKVFRYSTALEKHKLFVSGLPFSCTKEELEEICKAHGTVKDIRLVTNRAGKPKGLAYVEYENESQASQAVLKMDGMTIRENVIKVAISNPPQRKVPEKPEARKAPGSALLPRQVYGARGKGRTQLSLLPRALQRPSAATAQAENGPATPATTEAPKMSNADFAKLLLRKKLLCLLYK", "length": 965, "header": "tr|A0ABI0NTJ2-1|A0ABI0NTJ2_BOVIN Isoform 1 of Spliceosome associated factor 3, U4/U6 recycling protein OS=Bos taurus OX=9913 GN=SART3 PE=4 SV=1 CANONICAL=A0ABI0NTJ2-1" }, "locus": { "chromosome": "17", "start_pos": 64407436, "end_pos": 64364567, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152991.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152991.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104110.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104110.1" } ] } }, { "isoform_ac": "A0ABI0NUM8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTJ2/entry#A0ABI0NUM8-1", "sequence": { "sequence": "MATAAAASASEAEAEPKAGPEAEGEQDEAKAARARRKVLSRAVAAATYKTMGPEWDQQEEGVSESDGDEEYAMASSAESSPGEYEWGYDEEEKNQLEIERLEEQLSINVYDYNCHVDLIRLLRLEGELTKVRMARQKMSEIFPLTEELWLEWLHDEISMAMDGLDREHVYDLFERAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLAIWEAYREFESAIVEAARLEKVHSLFRRQLAIPLYDMEATFAEYEEWSEDPIPESVIQSYNKALQQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSAHSRAVRNCPWTVALWSRYLLALERHGVEHRVISVTFEKALSAGFIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRSAFARALEYLKQEVEERFSESGDPSCLIMQNWARIEARLCNNMQKARELWDSIMTRGNAKFANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGTLEDWDIAVQKTETRLARVNEQRIKAAEKEAALAQQEEEKVEQRKRARAEKKALKKKKKTRGADKHRADEDDEKEWGDDEEEQPSKRRRVENSVPPAGEAEPGSEADLSGSSAPAATESPSELKEVRVGARRRDVPKVPHDSSKDGVTVFVSNLPYGLGEPAATLRPLFEACGDVVEVRPIFSNRGDFRGYCYVEFREEAAALQALQLDRQSVEGRPMFVSPCVDKSKNPDFKVFRYSTALEKHKLFVSGLPFSCTKEELEEICKAHGTVKDIRLVTNRAGKPKGLAYVEYENESQASQAVLKMDGMTIRENVIKVAISNPPQRKVPEKPEARKAPGSALLPRQVYGARGKGRTQLSLLPRALQRPSAATAQAENGPATPATTEAPKMSNADFAKLLLRK", "length": 957, "header": "tr|A0ABI0NUM8-1|A0ABI0NUM8_BOVIN Computationally mapped isoform of Spliceosome associated factor 3, U4/U6 recycling protein OS=Bos taurus OX=9913 GN=SART3 PE=4 SV=1 CANONICAL=A0ABI0NTJ2-1" }, "locus": { "chromosome": "17", "start_pos": 64404864, "end_pos": 64364567, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145408.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145408.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104931.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104931.1" } ] } }, { "isoform_ac": "A0ABI0NZR9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTJ2/entry#A0ABI0NZR9-1", "sequence": { "sequence": "MATAAAASASEAEAEPKAGPEAEGEQDEAKAARARRKVLSRAVAAATYKTMGPEWDQQEEGVSESDGDEEYAMASSAESSPGEYEWGYDEEEKNQLEIERLEEQLSINVYDYNCHVDLIRLLRLEGELTKVRMARQKMSEIFPLTEELWLEWLHDEISMAMDGLDREHVYDLFERAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLAIWEAYREFESAIVEAARLEKVHSLFRRQLAIPLYDMEATFAEYEEWSEDPIPESVIQSYNKALQQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSAHSRAVRNCPWTVALWSRYLLALERHGVEHRVISVTFEKALSAGFIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRSAFARALEYLKQEVEERFSESGDPSCLIMQNWARIEARLCNNMQKARELWDSIMTRGNAKFANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGTLEDWDIAVQKTETRLARVNEQRIKAAEKEAALAQQEEEKVEQRKRARAEKKALKKKKKTRGADKHRADEDDEKEWGDDEEEQPSKRRRVENSVPPAGEAEPGSEADLSGSSAPAATESPSELKEVRVGARRRDVPKVPHDSSKDGVTVFVSNLPYGLGEPAATLRPLFEACGDVVEVRPIFSNRGDFRGYCYVEFREEAAALQALQLDRQSVEGRPMFVSPCVDKSKNPDFKVFRYSTALEKHKLFVSGLPFSCTKEELEEICKAHGTVKDIRLVTNRAGKPKGLAYVEYENESQASQAVLKMDGMTIRENVIKVAISNPPQRKVPEKPEARKAPGSALLPRQVYGARGKGRTQLSLLPRALQRPSAATAQAENGPATPATTEAPKMSNADFAKLLLRKLFPGTA", "length": 963, "header": "tr|A0ABI0NZR9-1|A0ABI0NZR9_BOVIN Computationally mapped isoform of Spliceosome associated factor 3, U4/U6 recycling protein OS=Bos taurus OX=9913 GN=SART3 PE=4 SV=1 CANONICAL=A0ABI0NTJ2-1" }, "locus": { "chromosome": "17", "start_pos": 64409339, "end_pos": 64364567, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145303.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145303.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106008.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106008.1" } ] } }, { "isoform_ac": "A0ABI0P1P0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTJ2/entry#A0ABI0P1P0-1", "sequence": { "sequence": "MAYWANPAGSLRPRAPMDVVHTLSINVYDYNCHVDLIRLLRLEGELTKVRMARQKMSEIFPLTEELWLEWLHDEISMAMDGLDREHVYDLFERAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLAIWEAYREFESAIVEAARLEKVHSLFRRQLAIPLYDMEATFAEYEEWSEDPIPESVIQSYNKALQQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSAHSRAVRNCPWTVALWSRYLLALERHGVEHRVISVTFEKALSAGFIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRSAFARALEYLKQEVEERFSESGDPSCLIMQNWARIEARLCNNMQKARELWDSIMTRGNAKFANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGTLEDWDIAVQKTETRLARVNEQRIKAAEKEAALAQQEEEKVEQRKRARAEKKALKKKKKTRGADKHRADEDDEKEWGDDEEEQPSKRRRVENSVPPAGEAEPGSEADLSGSSAPAATESPSELKEVRVGARRRDVPKVPHDSSKDGVTVFVSNLPYGLGEPAATLRPLFEACGDVVEVRPIFSNRGDFRGYCYVEFREEAAALQALQLDRQSVEGRPMFVSPCVDKSKNPDFKVFRYSTALEKHKLFVSGLPFSCTKEELEEICKAHGTVKDIRLVTNRAGKPKGLAYVEYENESQASQAVLKMDGMTIRENVIKVAISNPPQRKVPEKPEARKAPGSALLPRQVYGARGKGRTQLSLLPRALQRPSAATAQAENGPATPATTEAPKMSNADFAKLLLRK", "length": 875, "header": "tr|A0ABI0P1P0-1|A0ABI0P1P0_BOVIN Computationally mapped isoform of Spliceosome associated factor 3, U4/U6 recycling protein OS=Bos taurus OX=9913 GN=SART3 PE=4 SV=1 CANONICAL=A0ABI0NTJ2-1" }, "locus": { "chromosome": "17", "start_pos": 64404864, "end_pos": 64366088, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139418.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139418.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105352.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105352.1" } ] } }, { "isoform_ac": "A0ABI0P2S2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTJ2/entry#A0ABI0P2S2-1", "sequence": { "sequence": "MATAAAASASEAEAEPKAGPEAEGEQDEAKAARARRKVLSRAVAAATYKTMGPEWDQQEEGVSESDGDEEYAMASSAESSPGEYEWGYDEEEKNQLEIERLEEQLSINVYDYNCHVDLIRLLRLEGELTKVRMARQKMSEIFPLTEELWLEWLHDEISMAMDGLDREHVYDLFERAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLAIWEAYREFESAIVEAARLEKVHSLFRRQLAIPLYDMEATFAEYEEWSEDPIPESVIQSYNKALQQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSAHSRAVRNCPWTVALWSRYLLALERHGVEHRVISVTFEKALSAGFIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRSAFARALEYLKQEVEERFSESGDPSCLIMQNWARIEARLCNNMQKARELWDSIMTRGNAKFANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGTLEDWDIAVQKTETRLARVNEQRIKAAEKEAALAQQEEEKVEQRKRARAEKKALKKKKKTRGADKHRADEDDEKEWGDDEEEQPSKRRRVENSVPPAGEAEPGSEADLSGSSAPAATESPSELKEVRVGARRRDVPKVPHDSSKDGVTVFVSNLPYGLGEPAATLRPLFEACGDVVEVRPIFSNRGDFRGYCYVEFREEAAALQALQLDRQSVEGRPMFVSPCVDKSKNPDFKGLAYVEYENESQASQAVLKMDGMTIRENVIKVAISNPPQRKVPEKPEARKAPGSALLPRQVYGARGKGRTQLSLLPRALQRPSAATAQAENGPATPATTEAPKMSNADFAKLLLRK", "length": 906, "header": "tr|A0ABI0P2S2-1|A0ABI0P2S2_BOVIN Computationally mapped isoform of Spliceosome associated factor 3, U4/U6 recycling protein OS=Bos taurus OX=9913 GN=SART3 PE=4 SV=1 CANONICAL=A0ABI0NTJ2-1" }, "locus": { "chromosome": "17", "start_pos": 64404864, "end_pos": 64364567, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137076.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137076.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104998.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104998.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 936, "start_aa": "Thr", "end_pos": 936, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr936", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTJ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTJ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTJ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTJ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTJ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTJ2" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTJ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 850, "end_pos": 852, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NTJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTJ2" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 704, "end_pos": 782, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 936 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 850, "end_pos": 852 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], 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"url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ8/entry#names_and_taxonomy" } ] }, { "name": "arylsulfatase D", "type": "synonym", "evidence": [ { "id": "XP_024844238", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844238" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMJ8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC516494", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ8", "locus": {} } ], "crossref": [ { "id": "cd16159", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16159", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "516494", "url": "https://www.ncbi.nlm.nih.gov/gene/516494", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR42693", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42693", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42693:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42693:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024844238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844238", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NMJ8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NX76", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NX76-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPTVQRRRAAHAARDSLNLLLIMCLLLKTCELKSANTSKPNILLIMADDLGIGDLGCYGNDTLRTPNIDRLAEEGVRLTQHLAAAPLCTPSRAAFLTGRHAFRSGMDATDRYRALQWNAGSGGLPQNETTFARILQGQGYTTGLIGKWHQGVNCASRNDHCHHPLHHGFDYFYGMPFTLVNDCHPDRPPSLDSGLRARLWLYTQIMALGVLTIVAGKACRLISISWKLVLSVATLVLLFFTSWYASFGFVRRWNCILMRNHEVTEQPMVLERAASLVLKEAVSFIARNKQGPFLLFVSLLHVHIPLVTTERFLGKSRHGLYGDNVEEMDWLVGEILNAVEEHGLKNTTLTYFTSDHGGHLQARDGHVQLGGWNGIYRGGKGMAGWEGGIRVPGIFRWPGVLPAGHVIHEPTSLMDVFPTVVQLAGGQVPQDRVIDGRSLLPLLRGDAERSAHEFLFHYCGQYLHAARWHEKDSGRLWKVHYTTPDFHPEGAGACRGSSMCPCSGAGVTHHDPPLLFDLSGDPSEARPLSPDAGPVYREVVARVGRAVREHRRSVRPVPEQLSFQNVAWKPWLQPCCGPFPFCACSRDADPGET", "length": 594, "header": "tr|A0ABI0NMJ8-1|A0ABI0NMJ8_BOVIN Isoform 1 of Sulfatase N-terminal domain-containing protein OS=Bos taurus OX=9913 GN=LOC516494 PE=3 SV=1 CANONICAL=A0ABI0NMJ8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NMJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ8/entry#A0ABI0NMJ8-1", "sequence": { "sequence": "MAPTVQRRRAAHAARDSLNLLLIMCLLLKTCELKSANTSKPNILLIMADDLGIGDLGCYGNDTLRTPNIDRLAEEGVRLTQHLAAAPLCTPSRAAFLTGRHAFRSGMDATDRYRALQWNAGSGGLPQNETTFARILQGQGYTTGLIGKWHQGVNCASRNDHCHHPLHHGFDYFYGMPFTLVNDCHPDRPPSLDSGLRARLWLYTQIMALGVLTIVAGKACRLISISWKLVLSVATLVLLFFTSWYASFGFVRRWNCILMRNHEVTEQPMVLERAASLVLKEAVSFIARNKQGPFLLFVSLLHVHIPLVTTERFLGKSRHGLYGDNVEEMDWLVGEILNAVEEHGLKNTTLTYFTSDHGGHLQARDGHVQLGGWNGIYRGGKGMAGWEGGIRVPGIFRWPGVLPAGHVIHEPTSLMDVFPTVVQLAGGQVPQDRVIDGRSLLPLLRGDAERSAHEFLFHYCGQYLHAARWHEKDSGRLWKVHYTTPDFHPEGAGACRGSSMCPCSGAGVTHHDPPLLFDLSGDPSEARPLSPDAGPVYREVVARVGRAVREHRRSVRPVPEQLSFQNVAWKPWLQPCCGPFPFCACSRDADPGET", "length": 594, "header": "tr|A0ABI0NMJ8-1|A0ABI0NMJ8_BOVIN Isoform 1 of Sulfatase N-terminal domain-containing protein OS=Bos taurus OX=9913 GN=LOC516494 PE=3 SV=1 CANONICAL=A0ABI0NMJ8-1" }, "locus": { "chromosome": "Y", "start_pos": 1435751, "end_pos": 1420835, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151080.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151080.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106753.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106753.1" } ] } }, { "isoform_ac": "A0ABI0NX76-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ8/entry#A0ABI0NX76-1", "sequence": { "sequence": "MAPTVQRRRAAHAARDSLNLLLIMCLLLKTCELKSANTSKPNILLIMADDLGIGDLGCYGNDTLRTPNIDRLAEEGVRLTQHLAAAPLCTPSRAAFLTGRHAFRSGKWHQGVNCASRNDHCHHPLHHGFDYFYGMPFTLVNDCHPDRPPSLDSGLRARLWLYTQIMALGVLTIVAGKACRLISISWKLVLSVATLVLLFFTSWYASFGFVRRWNCILMRNHEVTEQPMVLERAASLVLKEAVSFIARNKQGPFLLFVSLLHVHIPLVTTERFLGKSRHGLYGDNVEEMDWLVGEILNAVEEHGLKNTTLTYFTSDHGGHLQARDGHVQLGGWNGIYRGGKGMAGWEGGIRVPGIFRWPGVLPAGHVIHEPTSLMDVFPTVVQLAGGQVPQDRVIDGRSLLPLLRGDAERSAHEFLFHYCGQYLHAARWHEKDSGRLWKVHYTTPDFHPEGAGACRGSSMCPCSGAGVTHHDPPLLFDLSGDPSEARPLSPDAGPVYREVVARVGRAVREHRRSVRPVPEQLSFQNVAWKPWLQPCCGPFPFCACSRDADPGET", "length": 553, "header": "tr|A0ABI0NX76-1|A0ABI0NX76_BOVIN Computationally mapped isoform of Sulfatase N-terminal domain-containing protein OS=Bos taurus OX=9913 GN=LOC516494 PE=3 SV=1 CANONICAL=A0ABI0NMJ8-1" }, "locus": { "chromosome": "Y", "start_pos": 1435751, "end_pos": 1420835, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147300.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147300.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105793.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105793.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMJ8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMJ8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NMJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ8" }, { "id": "PF00884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfatase N-terminal", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 426, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NMJ9-1", "uniprot_ac": "A0ABI0NMJ9", "uniprot_id": "A0ABI0NMJ9_BOVIN", "mass": { "chemical_mass": 35290.0, "monoisotopic_mass": 35290.0 }, "refseq": { "ac": "NP_001376855", "name": "olfactory receptor family 5 subfamily M member 3", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376855" }, "gene_names": [ { "name": "OR5M3", "type": "recommended", "evidence": [ { "id": "A0ABI0NMJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ9" } ] }, { "name": "OR5M3", "type": "synonym", "evidence": [ { "id": "NP_001376855", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376855" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NMJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 5 subfamily M member 3", "type": "synonym", "evidence": [ { "id": "NP_001376855", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376855" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376855", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376855" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMJ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ9#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMJ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR5M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ9", "locus": {} } ], "crossref": [ { "id": "cd15412", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15412", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "513633", "url": "https://www.ncbi.nlm.nih.gov/gene/513633", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376855", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376855", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NMJ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLNFTDVTEFILLGLTSRREWQVLSFIIFLLVYVVTVVGNIGMILLIKVSPQLSSPMYFFLSHLSFVDVWFSSNVTPKMLENLLSETKTISYAGCLVQCFFFIALVHVEVFILAVMAFDRYMAIGDPLLYGSKMSRTVCIRLISFPYVYGFLVSLAATLWTYGLYFCGKIEINHFYCADPPLIKMACAGTFVKEYTMLILAGINFVYSLTVVILSYLFILIAIVRMNSAEGRRKAFSTCGSHLTAVVMFYGTLIFMYLRRPTEESVEQGKMVAVFYTTVIPMLNPMIYSLRNRDVKEAMNKVISRTILTK", "length": 310, "header": "tr|A0ABI0NMJ9-1|A0ABI0NMJ9_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR5M3 PE=3 SV=1 CANONICAL=A0ABI0NMJ9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NMJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMJ9/entry#A0ABI0NMJ9-1", "sequence": { "sequence": "MLNFTDVTEFILLGLTSRREWQVLSFIIFLLVYVVTVVGNIGMILLIKVSPQLSSPMYFFLSHLSFVDVWFSSNVTPKMLENLLSETKTISYAGCLVQCFFFIALVHVEVFILAVMAFDRYMAIGDPLLYGSKMSRTVCIRLISFPYVYGFLVSLAATLWTYGLYFCGKIEINHFYCADPPLIKMACAGTFVKEYTMLILAGINFVYSLTVVILSYLFILIAIVRMNSAEGRRKAFSTCGSHLTAVVMFYGTLIFMYLRRPTEESVEQGKMVAVFYTTVIPMLNPMIYSLRNRDVKEAMNKVISRTILTK", "length": 310, "header": "tr|A0ABI0NMJ9-1|A0ABI0NMJ9_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR5M3 PE=3 SV=1 CANONICAL=A0ABI0NMJ9-1" }, "locus": { "chromosome": "15", "start_pos": 79774535, "end_pos": 79773606, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056246.4", "url": "https://www.ensembl.org/id/ENSBTAT00000056246.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106741.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106741.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377269" }, "gene_names": [ { "name": "OR10AB2", "type": "recommended", "evidence": [ { "id": "A0ABI0NMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMK1" } ] }, { "name": "OR10AB2", "type": "synonym", "evidence": [ { "id": "NP_001377269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377269" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 10 subfamily AB member 2", "type": "synonym", "evidence": [ { "id": "A0ABI0NMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMK1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 10 subfamily AB member 2", "type": "synonym", "evidence": [ { "id": "NP_001377269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377269" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377269", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377269" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMK1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMK1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMK1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMK1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR10AB2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMK1", "locus": {} } ], "crossref": [ { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "782791", "url": "https://www.ncbi.nlm.nih.gov/gene/782791", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein 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the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377059" }, "gene_names": [ { "name": "OR4C1L", "type": "recommended", "evidence": [ { "id": "A0ABI0NMN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMN2" } ] }, { "name": "OR4C1L", "type": "synonym", "evidence": [ { "id": "NP_001377059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377059" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 4 subfamily C member 1L", "type": "synonym", "evidence": [ { "id": "A0ABI0NMN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMN2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 140", "type": "synonym", "evidence": [ { "id": "NP_001377059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377059" } ] }, { "name": "olfactory receptor family 4 subfamily C member 1L", "type": "synonym", "evidence": [ { "id": "NP_001377059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377059" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377059", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377059" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMN2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMN2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMN2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMN2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4C1L", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMN2", "locus": {} } ], "crossref": [ { "id": "cd15939", "url": 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PE=3 SV=1 CANONICAL=A0ABI0NMN4-1" }, "locus": { "chromosome": "18", "start_pos": 65328276, "end_pos": 65317589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137394.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137394.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106838.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106838.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMN4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMN4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", 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{ "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059740323", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740323", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NMS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMS0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"ENSBTAP00000106519.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106519.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMS0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMS0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMS0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NMS0", "database": "UniProtKB", "url": 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"categories": [ "Protein Classification" ] }, { "id": "IPR046357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46512", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46512", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46512:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46512:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00254", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00254", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": 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"phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMV7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV7" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMV7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMV7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV7" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 193, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 201, "end_pos": 203 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NMW1-1", "uniprot_ac": "A0ABI0NMW1", "uniprot_id": "A0ABI0NMW1_BOVIN", "mass": { "chemical_mass": 33089.0, "monoisotopic_mass": 33089.0 }, "refseq": {}, "gene_names": [ { "name": "OR5T1B", "type": "recommended", "evidence": [ { "id": "A0ABI0NMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW1" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR5T1B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW1", "locus": {} } ], "crossref": [ { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NMW1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMW1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "FILMGFTDDSEVQIFLFLLFLAIYLFTMIGNLGLVFLVIMDSRLHNPMYYFLAALSFLDACYSSVITPKMLINFLSENKTISFLGCATQMFLFLTCGTTECFILAAMAYDRYVAIYNPLLYLVTMSPRVYVPLIISCYVVGVLHATLHTGATFTLSFCGSNEIRHVFCDIPPLLAISCSDTRMNQLLVFYFAGSIEISTILIVLISYGFILLAILRMGSAEGRRKVFSTCGSHLTGVSIFHGTVLFMYVRPSSSYALDHDMIVSVFYTIIIPMLNPIIYSLRNKDVKDAMKKVLG", "length": 295, "header": "tr|A0ABI0NMW1-1|A0ABI0NMW1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR5T1B PE=3 SV=1 CANONICAL=A0ABI0NMW1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NMW1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW1/entry#A0ABI0NMW1-1", "sequence": { "sequence": "FILMGFTDDSEVQIFLFLLFLAIYLFTMIGNLGLVFLVIMDSRLHNPMYYFLAALSFLDACYSSVITPKMLINFLSENKTISFLGCATQMFLFLTCGTTECFILAAMAYDRYVAIYNPLLYLVTMSPRVYVPLIISCYVVGVLHATLHTGATFTLSFCGSNEIRHVFCDIPPLLAISCSDTRMNQLLVFYFAGSIEISTILIVLISYGFILLAILRMGSAEGRRKVFSTCGSHLTGVSIFHGTVLFMYVRPSSSYALDHDMIVSVFYTIIIPMLNPIIYSLRNKDVKDAMKKVLG", "length": 295, "header": "tr|A0ABI0NMW1-1|A0ABI0NMW1_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR5T1B PE=3 SV=1 CANONICAL=A0ABI0NMW1-1" }, "locus": { "chromosome": "15", "start_pos": 78627166, "end_pos": 78626282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139860.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139860.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106973.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106973.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMW1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMW1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 279, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NMW8-1", "uniprot_ac": "A0ABI0NMW8", "uniprot_id": "A0ABI0NMW8_BOVIN", "mass": { "chemical_mass": 15843.0, "monoisotopic_mass": 15843.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0ABI0NMW8", "database": 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"mass": { "chemical_mass": 50457.0, "monoisotopic_mass": 50457.0 }, "refseq": {}, "gene_names": [ { "name": "PNPLA3", "type": "recommended", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] } ], "protein_names": [ { "name": "Acylglycerol transacylase", "type": "recommended", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.51", "type": "synonym", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.3", "type": "synonym", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.4", "type": "synonym", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2/entry#names_and_taxonomy" } ] }, { "name": "Adiponutrin", "type": "synonym", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2/entry#names_and_taxonomy" } ] }, { "name": "Calcium-independent phospholipase A2-epsilon", "type": "synonym", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2/entry#names_and_taxonomy" } ] }, { "name": "Lysophosphatidic acid acyltransferase", "type": "synonym", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2/entry#names_and_taxonomy" } ] }, { "name": "Patatin-like phospholipase domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids. Does not esterify other lysophospholipids. Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA. Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides. In vitro may express hydrolytic activity against glycerolipids triacylglycerol, diacylglycerol and monoacylglycerol, with a strong preference for oleic acid as the acyl moiety. However, the triacylglycerol hydrolase activity is controversial and may be very low. Possesses phospholipase A2 activity.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMZ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2#function" }, { "database": "UniProtKB", "id": "ARBA00053171", "url": "https://www.uniprot.org/uniprotkb/ARBA00053171#function" }, { "database": "UniProtKB", "id": "A0ABI0NWK8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWK8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMZ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PNPLA3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2", "locus": {} } ], "crossref": [ { "id": "cd07221", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07221", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12406", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12406", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12406:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12406:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01734", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01734", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "12044", "url": "https://www.rhea-db.org/rhea/12044", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "19709", "url": "https://www.rhea-db.org/rhea/19709", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "37131", "url": "https://www.rhea-db.org/rhea/37131", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "37143", "url": "https://www.rhea-db.org/rhea/37143", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "37159", "url": "https://www.rhea-db.org/rhea/37159", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "37443", "url": "https://www.rhea-db.org/rhea/37443", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "38323", "url": "https://www.rhea-db.org/rhea/38323", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "38327", "url": "https://www.rhea-db.org/rhea/38327", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "38331", "url": "https://www.rhea-db.org/rhea/38331", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "38387", "url": "https://www.rhea-db.org/rhea/38387", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44432", "url": "https://www.rhea-db.org/rhea/44432", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44436", "url": "https://www.rhea-db.org/rhea/44436", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44440", "url": "https://www.rhea-db.org/rhea/44440", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NMZ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWK8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWK8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYDPESGWSLSFAGCGFLCVYYVGVTRCLSEHAPHLLRQVQKFFGASSGALYCAFFLSGIPLDQTLQILMDLTRSARSQKFGIVHPGFSLSKHTRDGLQRHLPDNVHQLVSGKMVVSLTRVSDGKNVLVSDFHSKDEVVDALCCSCYVPFICGWIPPSFRGVRYVDGGVTDIMPFVDSKKTITVSPFYGESDICPKVKSTFFLNEGFTKLNMQFCTENLYLMFRSLLMLDVKMLGELCLQGYVDALRFLEKNGIREGPHPCLSAAPAEAESEPRSLEPLLGVATWEAGPEAVELLDHLRLRVLTWDEGVLETLSPELSMALRKAVRNPDGYRNRICNFLPVKIMSYVMLPCTLPVESAIAVVQRLVTWLPDMPGDIQWLWSATSHVCSQAMARLLPASRSQIPASGQRPSSTTRTLWASLGSLLLRGPGHPPSGRPAEARADNYDVRRMTCVLSL", "length": 455, "header": "tr|A0ABI0NMZ2-1|A0ABI0NMZ2_BOVIN Isoform 1 of Acylglycerol transacylase OS=Bos taurus OX=9913 GN=PNPLA3 PE=4 SV=1 CANONICAL=A0ABI0NMZ2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NMZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2/entry#A0ABI0NMZ2-1", "sequence": { "sequence": "MYDPESGWSLSFAGCGFLCVYYVGVTRCLSEHAPHLLRQVQKFFGASSGALYCAFFLSGIPLDQTLQILMDLTRSARSQKFGIVHPGFSLSKHTRDGLQRHLPDNVHQLVSGKMVVSLTRVSDGKNVLVSDFHSKDEVVDALCCSCYVPFICGWIPPSFRGVRYVDGGVTDIMPFVDSKKTITVSPFYGESDICPKVKSTFFLNEGFTKLNMQFCTENLYLMFRSLLMLDVKMLGELCLQGYVDALRFLEKNGIREGPHPCLSAAPAEAESEPRSLEPLLGVATWEAGPEAVELLDHLRLRVLTWDEGVLETLSPELSMALRKAVRNPDGYRNRICNFLPVKIMSYVMLPCTLPVESAIAVVQRLVTWLPDMPGDIQWLWSATSHVCSQAMARLLPASRSQIPASGQRPSSTTRTLWASLGSLLLRGPGHPPSGRPAEARADNYDVRRMTCVLSL", "length": 455, "header": "tr|A0ABI0NMZ2-1|A0ABI0NMZ2_BOVIN Isoform 1 of Acylglycerol transacylase OS=Bos taurus OX=9913 GN=PNPLA3 PE=4 SV=1 CANONICAL=A0ABI0NMZ2-1" }, "locus": { "chromosome": "5", "start_pos": 114640797, "end_pos": 114619223, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151464.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151464.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106935.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106935.1" } ] } }, { "isoform_ac": "A0ABI0NWK8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2/entry#A0ABI0NWK8-1", "sequence": { "sequence": "MYDPESGWSLSFAGCGFLCVYYVGVTRCLSEHAPHLLRQVQKFFGASSGALYCAFFLSGIPLDQTLQILMDLTRSARSQKFGIVHPGFSLSKHTRDGLQRHLPDNVHQLVSGKMVVSLTRVSDGKNVLVSDFHSKDEVVDALCCSCYVPFICGWIPPSFRGVRYVDGGVTDIMPFVDSKKTITVSPFYGESDICPKVKSTFFLNEGFTKLNMQFCTENLYLMFRSLLMLDVKMLGELCLQGYVDALRFLEKNGIREGPHPCLSAAPAEAESEPRSLEPLLGVATWEAGPEAVELLDHLRLRVLTWDEGVLETLSPELSMALRKAVRNPDGYRNRICNFLPVKIMSYVMLPCTLPVESAIAVVQRLVTWLPDMPGDIQWLWSATSHVCSQAMARLLPASRSQIPASGQRPSSTTRTLWASLGSLLLRGPGHPPSGRPAEARADNYDFSRSVSNNEL", "length": 455, "header": "tr|A0ABI0NWK8-1|A0ABI0NWK8_BOVIN Computationally mapped isoform of Acylglycerol transacylase OS=Bos taurus OX=9913 GN=PNPLA3 PE=4 SV=1 CANONICAL=A0ABI0NMZ2-1" }, "locus": { "chromosome": "5", "start_pos": 114652308, "end_pos": 114619223, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152245.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152245.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105424.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105424.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "1-acylglycerol-3-phosphate O-acyltransferase activity", "id": "GO:0003841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003841", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMZ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMZ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "triglyceride catabolic process", "id": "GO:0019433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019433", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMZ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12044", "name": "", "equation": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5PK46-1", "A0A3Q1LV96-1", "A0A3Q1MLE6-1", "Q3SZ79-1", "E1BJQ9-1", "Q5EA42-1", "P11151-1", "P16386-1", "P30122-1", "Q29458-1", "Q2KI18-1", "F1MC21-1", "Q0P5B7-1", "A0A3Q1M7B8-1", "F6RA94-1", "G5E5T0-1", "A0A3Q1LR40-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "12044", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12044" } ] }, { "id": "19709", "name": "", "equation": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95JH2-1", "A0AAA9S2I6-1", "A0AAA9SAV7-1", "Q5E9R2-1", "E1B770-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "19709", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19709" } ] }, { "id": "37131", "name": "", "equation": "1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95JH2-1", "A0AAA9SAV7-1", "E1B770-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "37131", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/37131" } ] }, { "id": "37143", "name": "", "equation": "1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95JH2-1", "A0AAA9SAV7-1", "E1B770-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "37143", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/37143" } ] }, { "id": "37159", "name": "", "equation": "1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95JH2-1", "A0AAA9SAV7-1", "E1B770-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "37159", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/37159" } ] }, { "id": "37443", "name": "", "equation": "1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95JH2-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "37443", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/37443" } ] }, { "id": "38323", "name": "", "equation": "2 1-(9Z-octadecenoyl)-glycerol = 1,2-di-(9Z-octadecenoyl)-glycerol + glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KI18-1", "G5E5T0-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "38323", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38323" } ] }, { "id": "38327", "name": "", "equation": "1-(9Z-octadecenoyl)-glycerol + 1,2-di-(9Z-octadecenoyl)-glycerol = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KI18-1", "G5E5T0-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "38327", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38327" } ] }, { "id": "38331", "name": "", "equation": "1-(9Z-octadecenoyl)-glycerol + 1,3-di-(9Z-octadecenoyl)-glycerol = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KI18-1", "G5E5T0-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "38331", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38331" } ] }, { "id": "38387", "name": "", "equation": "1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = 1,3-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KI18-1", "G5E5T0-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "38387", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38387" } ] }, { "id": "44432", "name": "", "equation": "2 a 1-acylglycerol = a 1,2-diacylglycerol + glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KI18-1", "G5E5T0-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "44432", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44432" } ] }, { "id": "44436", "name": "", "equation": "a 1-acylglycerol + a 1,2-diacylglycerol = a triacylglycerol + glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KI18-1", "G5E5T0-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "44436", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44436" } ] }, { "id": "44440", "name": "", "equation": "a 1-acylglycerol + a 1,3-diacylglycerol = a triacylglycerol + glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KI18-1", "G5E5T0-1", "A0AAA9S3G3-1", "A0ABI0NMZ2-1" ], "evidence": [ { "id": "44440", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44440" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LR40", "gene_name": "LIPG", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LR40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR40" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LR40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR40" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "A0A3Q1LR40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR40" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A3Q1LR40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR40" } ] } ] }, { "uniprot_ac": "A0A3Q1LV96", "gene_name": "PLB1", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] } ] }, { "uniprot_ac": "A0A3Q1M7B8", "gene_name": "PNLIPRP1", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1M7B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7B8" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A3Q1M7B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7B8" } ] } ] }, { "uniprot_ac": "A0A3Q1MLE6", "gene_name": "LIPE", "activity": [ { "ec_number": "3.1.1.23", "activity": "Hydrolyzes glycerol monoesters of long-chain fatty acids.", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] }, { "ec_number": "3.1.1.79", "activity": "a monoacylglycerol + H2O = glycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] }, { "ec_number": "3.1.1.23", "activity": "", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] }, { "ec_number": "3.1.1.79", "activity": "", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] } ] }, { "uniprot_ac": "A0AAA9S2I6", "gene_name": "AGPAT4", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0AAA9S2I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2I6" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "A0AAA9S2I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2I6" } ] } ] }, { "uniprot_ac": "A0AAA9S3G3", "gene_name": "LOC100297709", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "A0AAA9S3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3G3" } ] } ] }, { "uniprot_ac": "A0AAA9SAV7", "gene_name": "AGPAT2", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0AAA9SAV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAV7" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "A0AAA9SAV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAV7" } ] } ] }, { "uniprot_ac": "A0ABI0NMZ2", "gene_name": "PNPLA3", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0ABI0NMZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ2" } ] } ] }, { "uniprot_ac": "A5PK46", "gene_name": "PNLIPRP2", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A5PK46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PK46" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A5PK46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PK46" } ] }, { "ec_number": "3.1.1.26", "activity": "a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 a fatty acid + 2 H(+).", "evidence": [ { "id": "A5PK46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PK46" } ] } ] }, { "uniprot_ac": "E1B770", "gene_name": "LPCAT2", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] }, { "ec_number": "2.3.1.23", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] }, { "ec_number": "2.3.1.67", "activity": "a 1-O-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] }, { "ec_number": "2.3.1.25", "activity": "a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] }, { "ec_number": "2.3.1.23", "activity": "", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] }, { "ec_number": "2.3.1.25", "activity": "", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] }, { "ec_number": "2.3.1.67", "activity": "", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] } ] }, { "uniprot_ac": "E1BJQ9", "gene_name": "PNLIP", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "E1BJQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJQ9" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "E1BJQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJQ9" } ] } ] }, { "uniprot_ac": "F1MC21", "gene_name": "PNLIPRP3", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "F1MC21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC21" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "F1MC21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC21" } ] } ] }, { "uniprot_ac": "F6RA94", "gene_name": "DAGLB", "activity": [ { "ec_number": "3.1.1.116", "activity": "a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "F6RA94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RA94" } ] }, { "ec_number": "3.1.1.116", "activity": "", "evidence": [ { "id": "F6RA94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RA94" } ] } ] }, { "uniprot_ac": "G5E5T0", "gene_name": "PNPLA2", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] } ] }, { "uniprot_ac": "P11151", "gene_name": "LPL", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "P11151", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11151" } ] }, { "ec_number": "3.1.1.34", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "P11151", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11151" } ] }, { "ec_number": "3.1.1.34", "activity": "", "evidence": [ { "id": "P11151", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11151" } ] } ] }, { "uniprot_ac": "P16386", "gene_name": "LIPE", "activity": [ { "ec_number": "3.1.1.23", "activity": "Hydrolyzes glycerol monoesters of long-chain fatty acids.", "evidence": [ { "id": "P16386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16386" } ] }, { "ec_number": "3.1.1.79", "activity": "a monoacylglycerol + H2O = glycerol + a fatty acid + H(+).", "evidence": [ { "id": "P16386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16386" } ] }, { "ec_number": "3.1.1.79", "activity": "", "evidence": [ { "id": "P16386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16386" } ] } ] }, { "uniprot_ac": "P30122", "gene_name": "CEL", "activity": [ { "ec_number": "3.1.1.13", "activity": "a cholesterol ester + H2O = cholesterol + a fatty acid + H(+).", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.6", "activity": "an acetyl ester + H2O = an aliphatic alcohol + acetate + H(+).", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.13", "activity": "", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.6", "activity": "", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "P30122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30122" } ] } ] }, { "uniprot_ac": "Q0P5B7", "gene_name": "AADAC", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "Q0P5B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5B7" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "Q0P5B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5B7" } ] } ] }, { "uniprot_ac": "Q29458", "gene_name": "LIPF", "activity": [ { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "Q29458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29458" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "Q29458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29458" } ] } ] }, { "uniprot_ac": "Q2KI18", "gene_name": "PNPLA2", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "Q2KI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI18" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "Q2KI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI18" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "Q2KI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI18" } ] } ] }, { "uniprot_ac": "Q3SZ79", "gene_name": "LIPC", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "Q3SZ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZ79" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "Q3SZ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZ79" } ] }, { 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"site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMZ8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NMZ8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMZ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": 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triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377184" }, "gene_names": [ { "name": "OR2B37", "type": "recommended", "evidence": [ { "id": "A0ABI0NN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN06" } ] }, { "name": "OR2B37", "type": "synonym", "evidence": [ { "id": "NP_001377184", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377184" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN06/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2G3", "type": "synonym", "evidence": [ { "id": "NP_001377184", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377184" } ] }, { "name": "olfactory receptor family 2 subfamily B member 37", "type": "synonym", "evidence": [ { "id": "NP_001377184", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377184" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377184", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377184" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NN06", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN06#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NN06", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN06" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2B37", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN06", "locus": {} } ], "crossref": [ { "id": "cd15947", "url": 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a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377745" }, "gene_names": [ { "name": "OR9M6", "type": "recommended", "evidence": [ { "id": "A0ABI0NNB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNB7" } ] }, { "name": "OR9M6", "type": "synonym", "evidence": [ { "id": "NP_001377745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377745" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 9 subfamily M member 6", "type": "synonym", "evidence": [ { "id": "A0ABI0NNB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNB7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 9 subfamily M member 6", "type": "synonym", "evidence": [ { "id": "NP_001377745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377745" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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[provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377745", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377745" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNB7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNB7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNB7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNB7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR9M6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNB7", "locus": {} } ], "crossref": [ { "id": "119646073", "url": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NNB9-1", "uniprot_ac": "A0ABI0NNB9", "uniprot_id": "A0ABI0NNB9_BOVIN", "mass": { "chemical_mass": 38610.0, "monoisotopic_mass": 38610.0 }, "refseq": {}, "gene_names": [ { "name": "LOC613867", "type": "recommended", "evidence": [ { "id": "A0ABI0NNB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNB9" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NNB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNB9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": 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"MSSASPSAAAVQLCYEHLNGSCVKTPCSPGPRLILYTVFIFGAVLAVFGNLLVMISILHFKQLHSPTNFLIASLACADFLLGVTVMPFSTVRSVESCWYFGESYCKFHTCFDGSFCYASIYHLCFISLDRYIAITDPLVYPTRFTESVSGMCIAFSWLFSIIYSFSLLGTGANAARLEGLVSALTCVGGCQIAVNQSWVLVNFLLFFIRTLVMIVLYSKIFLIAKQQARKIESLNNKTGRCSDSFQDRVAKRERKAARTLGVAVVAFLVSWLPYFLDAIIDAFLGFITPTYVYEILVWIAYYNSAMNPLIYAFFYPWFRKAIKLIVTGKVLRANSSTVNLFSGRAK", "length": 346, "header": "tr|A0ABI0NNB9-1|A0ABI0NNB9_BOVIN Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Bos taurus OX=9913 GN=LOC613867 PE=3 SV=1 CANONICAL=A0ABI0NNB9-1" }, "locus": { "chromosome": "9", "start_pos": 70581860, "end_pos": 70580357, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154030.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154030.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106816.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106816.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": 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334, "end_pos": 336, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NNB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNB9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 311, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 }, { 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"count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NND0-1", "uniprot_ac": "A0ABI0NND0", "uniprot_id": "A0ABI0NND0_BOVIN", "mass": { "chemical_mass": 46953.0, "monoisotopic_mass": 46953.0 }, "refseq": { "ac": "XP_010817433", "name": "ras-related protein Rab-40C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010817433" }, "gene_names": [ { "name": "RAB40C", "type": "recommended", "evidence": [ { "id": "A0ABI0NND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND0" } ] }, { "name": "RAB40C", "type": "synonym", "evidence": [ { "id": "XP_010817433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010817433" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0ABI0NND0", "database": 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"url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03742", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "618031", "url": "https://www.ncbi.nlm.nih.gov/gene/618031", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036036", "database": "InterPro", "categories": [ "Protein 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"sequence": { "sequence": "MTRASPRRPRASPPHRRPTILTAAQPSSPPPAALLGPPGPPPPHTILHRPGAHAGAEVPPPEATPSADWLSSPRHAPLSKSAASEGAEANGPLRPVRGFRGGSGRDFPETPVFPRLAASPRLGDGRRPAPYAEGGAYANNLELQAPDWSAGGLRRRAPRRRGNAGEARARVSDDGHAGQPGQELRLPAQVPAGGRQRRGQGRDPGELAGRRGRVPVRLQQRDRLQDNHHPAGRPAGQAGALGILLVYDITNRWSFDGIDRWIKEIDEHAPGVPRILVGNRLHLAFKRQVPTEQARAYAEKNCMTFFEVSPLCNFNVIESFTELSRIVLMRHGMEKIWRPNRVFSLQDLCCRAIVSCTPVHLIDKLPLPVTIKSHLKSFSMANGMNAVMMHGRSYSLASGAGGGGSKGNSLKRSKSIRPPQSPPQNCSRSNCKIS", "length": 434, "header": "tr|A0ABI0NND0-1|A0ABI0NND0_BOVIN Isoform 1 of small monomeric GTPase OS=Bos taurus OX=9913 GN=RAB40C PE=3 SV=1 CANONICAL=A0ABI0NND0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NND0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND0/entry#A0ABI0NND0-1", "sequence": { "sequence": "MTRASPRRPRASPPHRRPTILTAAQPSSPPPAALLGPPGPPPPHTILHRPGAHAGAEVPPPEATPSADWLSSPRHAPLSKSAASEGAEANGPLRPVRGFRGGSGRDFPETPVFPRLAASPRLGDGRRPAPYAEGGAYANNLELQAPDWSAGGLRRRAPRRRGNAGEARARVSDDGHAGQPGQELRLPAQVPAGGRQRRGQGRDPGELAGRRGRVPVRLQQRDRLQDNHHPAGRPAGQAGALGILLVYDITNRWSFDGIDRWIKEIDEHAPGVPRILVGNRLHLAFKRQVPTEQARAYAEKNCMTFFEVSPLCNFNVIESFTELSRIVLMRHGMEKIWRPNRVFSLQDLCCRAIVSCTPVHLIDKLPLPVTIKSHLKSFSMANGMNAVMMHGRSYSLASGAGGGGSKGNSLKRSKSIRPPQSPPQNCSRSNCKIS", "length": 434, "header": "tr|A0ABI0NND0-1|A0ABI0NND0_BOVIN Isoform 1 of small monomeric GTPase OS=Bos taurus OX=9913 GN=RAB40C PE=3 SV=1 CANONICAL=A0ABI0NND0-1" }, "locus": { "chromosome": "25", "start_pos": 538341, "end_pos": 517353, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136303.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136303.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104313.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104313.1" } ] } }, { "isoform_ac": "A0ABI0NQ82-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND0/entry#A0ABI0NQ82-1", "sequence": { "sequence": "GSPRSRASVRRSWGSCSRTHVPCKCGWNRSETPLFSTPWFPRKSAPHCSPVRLPFSGGVTVRRRRVARVLEERYGKTTVLSQQIPHVEGGSTEPLRSLTVRWPPARRWTGHATGILLVYDITNRWSFDGIDRWIKEIDEHAPGVPRILVGNRLHLAFKRQVPTEQARAYAEKNCMTFFEVSPLCNFNVIESFTELSRIVLMRHGMEKIWRPNRVFSLQDLCCRAIVSCTPVHLIDKLPLPVTIKSHLKSFSMANGMNAVMMHGRSYSLASGAGGGGSKGNSLKRSKSIRPPQSPPQNCSRSNCKIS", "length": 306, "header": "tr|A0ABI0NQ82-1|A0ABI0NQ82_BOVIN Computationally mapped isoform of small monomeric GTPase OS=Bos taurus OX=9913 GN=RAB40C PE=3 SV=1 CANONICAL=A0ABI0NND0-1" }, "locus": { "chromosome": "25", "start_pos": 538341, "end_pos": 536395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146099.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146099.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105416.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105416.1" } ] } }, { "isoform_ac": "A0ABI0P1V7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND0/entry#A0ABI0P1V7-1", "sequence": { "sequence": "ASRKGGGLRGRDQCAGGPVAVGGLLQRRPVAKWRAGRGAVVARGRVAGIDYKTTTILLDGRRVKLELWDTSGQGRFCTIFRSYSRGAQGILLVYDITNRWSFDGIDRWIKEIDEHAPGVPRILVGNRLHLAFKRQVPTEQARAYAEKNCMTFFEVSPLCNFNVIESFTELSRIVLMRHGMEKIWRPNRVFSLQDLCCRAIVSCTPVHLIDKLPLPVTIKSHLKSFSMANGMNAVMMHGRSYSLASGAGGGGSKGNSLKRSKSIRPPQSPPQNCSRSNCKIS", "length": 281, "header": "tr|A0ABI0P1V7-1|A0ABI0P1V7_BOVIN Computationally mapped isoform of small monomeric GTPase OS=Bos taurus OX=9913 GN=RAB40C PE=3 SV=1 CANONICAL=A0ABI0NND0-1" }, "locus": { "chromosome": "25", "start_pos": 538341, "end_pos": 517800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144015.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144015.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107079.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107079.1" } ] } }, { "isoform_ac": "A0ABI0P523-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND0/entry#A0ABI0P523-1", "sequence": { "sequence": "RGVGLPVGRRPPPPGSAAPWECGRGPRARERRWARRAARSRATTTCSSSCWWATATWARARSWRACRTARPSPRTPTATGILLVYDITNRWSFDGIDRWIKEIDEHAPGVPRILVGNRLHLAFKRQVPTEQARAYAEKNCMTFFEVSPLCNFNVIESFTELSRIVLMRHGMEKIWRPNRVFSLQDLCCRAIVSCTPVHLIDKLPLPVTIKSHLKSFSMANGMNAVMMHGRSYSLASGAGGGGSKGNSLKRSKSIRPPQSPPQNCSRSNCKIS", "length": 272, "header": "tr|A0ABI0P523-1|A0ABI0P523_BOVIN Computationally mapped isoform of small monomeric GTPase OS=Bos taurus OX=9913 GN=RAB40C PE=3 SV=1 CANONICAL=A0ABI0NND0-1" }, "locus": { "chromosome": "25", "start_pos": 538341, "end_pos": 517924, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153004.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153004.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106583.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106583.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 64, "start_aa": "Thr", "end_pos": 64, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr64", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NND0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NND0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND0" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NND0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NND0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NND0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q08E00-1", "Q5E9J3-1", "A6QP66-1", "Q2KHU8-1", "Q2KIA5-1", "F1MM29-1", "P08239-1", "P04896-1", "P63097-1", "Q7YS69-1", "Q0VCJ7-1", "A0AAA9SVR8-1", "P81948-1", "Q2KJ93-1", "A0AAA9TES1-1", "P61223-1", "Q2HJB8-1", "Q0IIG7-1", "Q3ZCJ7-1", "Q27957-1", "Q2HJ86-1", "A0A3Q1LMP2-1", "F1MB25-1", "Q58DS9-1", "A0AAA9S306-1", "A0A3Q1NEF8-1", "A4FV54-1", "A6H7I5-1", "F2Z4D5-1", "G3N1U2-1", "O18956-1", "P62998-1", "Q32KN8-1", "Q3MHP2-1", "Q3T054-1", "Q3T0F5-1", "Q3T0T7-1", "Q56JV3-1", "F1MNI4-1", "Q8HZJ5-1", "P61585-1", "P62833-1", "P68103-1", "Q08DI5-1", "Q2HJH2-1", "Q2T9U1-1", "Q2TBH7-1", "Q3MHP5-1", "Q3SX43-1", "Q3SYU2-1", "P81947-1", "P84080-1", "Q08DF4-1", "Q2KI07-1", "Q2TA29-1", "Q3T0D7-1", "A6QLJ3-1", "A6QNM2-1", "A6QR46-1", "Q1LZ78-1", "Q2KHZ2-1", "G3MYK6-1", "Q58D56-1", "Q32KW9-1", "P11023-1", "Q58DW6-1", "Q9TU25-1", "P10948-1", "Q2HJI8-1", "P10949-1", "Q0IIG8-1", "Q29RR0-1", "Q32PH8-1", "Q58DS5-1", "Q1RMR4-1", "Q3ZC27-1", "P49410-1", "A0A140T898-1", "E1BPU0-1", "A0AAA9S5W8-1", "A0AAA9SLN0-1", "A0AAF6Z672-1", "Q17R06-1", "Q58D72-1", "P82922-1", "Q2HJF8-1", "Q17QU4-1", "Q2YDM7-1", "A0AAA9T9T1-1", "A0A3Q1MDX0-1", "F1N2J9-1", "Q17QB7-1", "Q3SWY9-1", "Q5E9M9-1", "A0A3S5ZPA2-1", "A0AAA9SV95-1", "A0AAA9TWE6-1", "F1N6Y7-1", "F1N7V2-1", "A0AAA9SGM6-1", "A0AAA9TNQ2-1", "A0AAA9TS74-1", "F6Q1G9-1", "A0AAF6YXF5-1", "A5D7J5-1", "P04695-1", "Q3ZBW5-1", "A4FUD1-1", "A0A3Q1M0B9-1", "A6H7F2-1", "F1MHP4-1", "A0A3Q1MGR4-1", "A0A3Q1NCE9-1", "Q0P5E2-1", "Q32LJ6-1", "Q58DC5-1", "Q08DA0-1", "A0ABI0NND0-1", "E1BJA0-1", "A0A3Q1N147-1", "A0AAF6YME1-1", "F1MX39-1", "Q1RMJ6-1", "Q2HJ68-1", "Q2HJG3-1", "Q17QI8-1", "Q3SZA1-1", "A0ABI0NZ89-1", "A0ABI0P4Y3-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A140T898", "gene_name": "RAB13", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A140T898", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T898" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A140T898", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T898" } ] } ] }, { "uniprot_ac": "A0A3Q1LMP2", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] } ] }, { "uniprot_ac": "A0A3Q1M0B9", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1M0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B9" } ] } ] }, { "uniprot_ac": "A0A3Q1MDX0", "gene_name": "DNM3", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MDX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX0" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX0" } ] } ] }, { "uniprot_ac": "A0A3Q1MGR4", "gene_name": "RAB37", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] } ] }, { "uniprot_ac": "A0A3Q1N147", "gene_name": "RAB1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1N147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N147" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1N147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N147" } ] } ] }, { "uniprot_ac": "A0A3Q1NCE9", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NCE9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1NCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NCE9" } ] } ] }, { "uniprot_ac": "A0A3Q1NEF8", "gene_name": "RAC1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NEF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NEF8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1NEF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NEF8" } ] } ] }, { "uniprot_ac": "A0A3S5ZPA2", "gene_name": "RAB40B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPA2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPA2" } ] } ] }, { "uniprot_ac": "A0AAA9S306", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S306" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0AAA9S306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S306" } ] } ] }, { "uniprot_ac": "A0AAA9S5W8", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5W8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9S5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5W8" } ] } ] }, { "uniprot_ac": "A0AAA9SGM6", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SGM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9SGM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM6" } ] } ] }, { "uniprot_ac": "A0AAA9SLN0", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SLN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLN0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9SLN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLN0" } ] } ] }, { "uniprot_ac": "A0AAA9SV95", "gene_name": "RAB34", "activity": [ { "ec_number": 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"A0ABI0NND1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NND1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPRLGTFCCPTRDAATQLALVFQPRAFHALCLGSGALRLALGLLQLRPGRRPAGPGIASASPATSARVPASVRIVRAATACDLLGCLGIAVRSAVWLGFPSFVDDISAVNNTDVWPAVFCVGSALWIQLLYSACFWWWFCYAVDAYLVIQRSAGQSTILLYHLMTWGLAALLSVEGALMLYYPSMARCERGLEHAIPHYITTYLPLLLVLVGNPILFRKTVTAVASLLKGRQGIYTENERRMGAMIKTRFFKIMLVFIVCWFSNVINESLLFYLEMQPDINSSSLKQVRNAAKTTWFMMGILNPAQGFLLSLAFYGWTGCRLTLPGPSKEIQWDSMTTSATEGAPPSPGGPQEPGEGPAPKKELPGGTHTSDEALSLLSEGSGGSTIEIHIASGSRGGKAPDSLPKVQGTP", "length": 413, "header": "tr|A0ABI0NND1-1|A0ABI0NND1_BOVIN Isoform 1 of G-protein coupled receptor 143 OS=Bos taurus OX=9913 GN=GPR143 PE=3 SV=1 CANONICAL=A0ABI0NND1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NND1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND1/entry#A0ABI0NND1-1", "sequence": { "sequence": "MASPRLGTFCCPTRDAATQLALVFQPRAFHALCLGSGALRLALGLLQLRPGRRPAGPGIASASPATSARVPASVRIVRAATACDLLGCLGIAVRSAVWLGFPSFVDDISAVNNTDVWPAVFCVGSALWIQLLYSACFWWWFCYAVDAYLVIQRSAGQSTILLYHLMTWGLAALLSVEGALMLYYPSMARCERGLEHAIPHYITTYLPLLLVLVGNPILFRKTVTAVASLLKGRQGIYTENERRMGAMIKTRFFKIMLVFIVCWFSNVINESLLFYLEMQPDINSSSLKQVRNAAKTTWFMMGILNPAQGFLLSLAFYGWTGCRLTLPGPSKEIQWDSMTTSATEGAPPSPGGPQEPGEGPAPKKELPGGTHTSDEALSLLSEGSGGSTIEIHIASGSRGGKAPDSLPKVQGTP", "length": 413, "header": "tr|A0ABI0NND1-1|A0ABI0NND1_BOVIN Isoform 1 of G-protein coupled receptor 143 OS=Bos taurus OX=9913 GN=GPR143 PE=3 SV=1 CANONICAL=A0ABI0NND1-1" }, "locus": { "chromosome": "Y", "start_pos": 6818885, "end_pos": 6789611, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144320.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144320.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107157.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107157.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NND1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND1" } ], "pmid": "" }, { "name": "dopamine binding", "id": "GO:0035240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035240", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NND1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND1" } ], "pmid": "" }, { "name": "L-DOPA binding", "id": "GO:0072544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072544", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NND1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND1" } ], "pmid": "" }, { "name": "L-tyrosine binding", "id": "GO:0072545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072545", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NND1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NND1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NND1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 283, "end_pos": 285 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NNE3-1", "uniprot_ac": "A0ABI0NNE3", "uniprot_id": "A0ABI0NNE3_BOVIN", "mass": { "chemical_mass": 60837.0, "monoisotopic_mass": 60837.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NNE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNE3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May function as a transcription factor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNE3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNE3#function" }, { "database": "UniProtKB", "id": "ARBA00003729", "url": "https://www.uniprot.org/uniprotkb/ARBA00003729#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNE3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNE3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNE3", "locus": {} } ], "crossref": [ { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NNE3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNE3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P145", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P145", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P145-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P145-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIPLSKVDSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYKQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPG", "length": 542, "header": "tr|A0ABI0NNE3-1|A0ABI0NNE3_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NNE3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NNE3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNE3/entry#A0ABI0NNE3-1", "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIPLSKVDSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYKQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPG", "length": 542, "header": "tr|A0ABI0NNE3-1|A0ABI0NNE3_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NNE3-1" }, "locus": { "chromosome": "Y", "start_pos": 33261302, "end_pos": 33259674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140333.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140333.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107289.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107289.1" } ] } }, { "isoform_ac": "A0ABI0P145-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNE3/entry#A0ABI0P145-1", "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIPLSKVDSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQQLQIIILCRCGCTFQSIPW", "length": 424, "header": "tr|A0ABI0P145-1|A0ABI0P145_BOVIN Computationally mapped isoform of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NNE3-1" }, "locus": { "chromosome": "Y", "start_pos": 33261302, "end_pos": 33260023, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143664.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143664.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106643.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106643.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNE3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNE3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", 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"header": "tr|A0ABI0NRW8-1|A0ABI0NRW8_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NRW8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NNS4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRW8/entry#A0ABI0NNS4-1", "sequence": { "sequence": "MPRSHPVSPRMPVGLQISGAMDGSYHWPSFLHSHPGQGQCRDTEQTTFRLRYLEPWMGVTTGHPFFIPILDRVSAEIRNKPPSDWERLVPPLLVTQHLLSCRLHLCICPGLDTQKHTHKHSQHKHMCVYTHAWHGDTNANRECRCFRS", "length": 148, "header": "tr|A0ABI0NNS4-1|A0ABI0NRW8_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NRW8-1" }, "locus": { "chromosome": "Y", "start_pos": 28242896, "end_pos": 28118637, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152494.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152494.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104435.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104435.1" } ] } }, { "isoform_ac": "A0ABI0NRW8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRW8/entry#A0ABI0NRW8-1", "sequence": { "sequence": "MTKSEILLHRDCSNSLKCRCTLLPLRPPKPVARPQRKEGILVRTFSMHHGVSLAGRLLPRPWTLKTSRPRTAPRGFPVSHSPEVLWDMQLLLTHSVPSLTGSSGQRVKHVQPPVLSSPFCTAREAGWKCLEACHAHILSLLGCLWVCRYSLL", "length": 152, "header": "tr|A0ABI0NRW8-1|A0ABI0NRW8_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NRW8-1" }, "locus": { "chromosome": "Y", "start_pos": 28243291, "end_pos": 28242836, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143986.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143986.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104986.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104986.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NNU4-1", "uniprot_ac": "A0ABI0NNU4", "uniprot_id": "A0ABI0NNU4_BOVIN", "mass": { "chemical_mass": 90400.0, "monoisotopic_mass": 90400.0 }, "refseq": { "ac": "XP_059739952", "name": "zinc finger Y-chromosomal protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739952" }, "gene_names": [ { "name": "ZFY", "type": "recommended", "evidence": [ { "id": "A0ABI0NNU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNU4" } ] }, { "name": "ZFY", "type": "synonym", "evidence": [ { "id": "XP_059739952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739952" } ] } ], "protein_names": [ { "name": "Zinc finger protein, Y-linked", "type": "synonym", "evidence": [ { "id": "A0ABI0NNU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNU4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger Y-chromosomal protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059739952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739952" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNU4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNU4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZFY", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNU4", "locus": {} } ], "crossref": [ { "id": "280962", "url": "https://www.ncbi.nlm.nih.gov/gene/280962", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF189", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF189", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13909", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13909", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059739952", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739952", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NNU4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNU4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1E2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1E2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1E2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEDEFELQPQEPNSCFDGIGTDATHMDGDQIVVEVQETVFVSDVVDSDITVHNFVPDDPDSVVIQDVIENVVIEDVQCSDILEEADVSENVIIPEQMLSSDVTEEVSLAHCTVPDDVLASDITSASMSMPEHVLTSESVHVSDVGHVEHIVHGSVVEAEIVTDPLTADVVSEEVLVADCASEAVIDANGIPVDQQDDDKGNCEDYLMISLDDDGKMEQDCSAGMTIDRESEIDPCKVDGTCPEVIKVYIFKADPGEDDLGGTVDIVESEPENDHGVELLDQNNSIRMPREKMVYMTVNDSQQEDEDLNVAEIADEVYMEVIVGEEDAAVAAAAATTVHEQEMDDSEIKTFMPIAWAAAYGNNSDGIENRSGTASALLHIDESAGLGRLTKHKPKKRRRPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLTKKKYRCTDCDYTTNKKISLHNHLESHKLTSKSEKAIECDDCGKHFSHAGALFTHKMVHKEKGASKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGEKPYQCQYCEYRSADSSNLKTHVKTKHSKEMSFKCDICLLTFSDTKEVQQHALIHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKHVAAHKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCKKGFRQQNELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHITRHHKEVGLP", "length": 801, "header": "tr|A0ABI0NNU4-1|A0ABI0NNU4_BOVIN Isoform 1 of Zinc finger protein, Y-linked OS=Bos taurus OX=9913 GN=ZFY PE=3 SV=1 CANONICAL=A0ABI0NNU4-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NNU4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNU4/entry#A0ABI0NNU4-1", "sequence": { "sequence": "MDEDEFELQPQEPNSCFDGIGTDATHMDGDQIVVEVQETVFVSDVVDSDITVHNFVPDDPDSVVIQDVIENVVIEDVQCSDILEEADVSENVIIPEQMLSSDVTEEVSLAHCTVPDDVLASDITSASMSMPEHVLTSESVHVSDVGHVEHIVHGSVVEAEIVTDPLTADVVSEEVLVADCASEAVIDANGIPVDQQDDDKGNCEDYLMISLDDDGKMEQDCSAGMTIDRESEIDPCKVDGTCPEVIKVYIFKADPGEDDLGGTVDIVESEPENDHGVELLDQNNSIRMPREKMVYMTVNDSQQEDEDLNVAEIADEVYMEVIVGEEDAAVAAAAATTVHEQEMDDSEIKTFMPIAWAAAYGNNSDGIENRSGTASALLHIDESAGLGRLTKHKPKKRRRPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLTKKKYRCTDCDYTTNKKISLHNHLESHKLTSKSEKAIECDDCGKHFSHAGALFTHKMVHKEKGASKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGEKPYQCQYCEYRSADSSNLKTHVKTKHSKEMSFKCDICLLTFSDTKEVQQHALIHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKHVAAHKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCKKGFRQQNELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHITRHHKEVGLP", "length": 801, "header": "tr|A0ABI0NNU4-1|A0ABI0NNU4_BOVIN Isoform 1 of Zinc finger protein, Y-linked OS=Bos taurus OX=9913 GN=ZFY PE=3 SV=1 CANONICAL=A0ABI0NNU4-1" }, "locus": { "chromosome": "Y", "start_pos": 8010896, "end_pos": 7989693, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148012.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148012.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107114.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107114.1" } ] } }, { "isoform_ac": "A0ABI0P1E2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNU4/entry#A0ABI0P1E2-1", "sequence": { "sequence": "MDEDEFELQPQEPNSCFDGIGTDATHMDGDQIVVEVQETVFVSDVVDSDITVHNFVPDDPDSVVIQDVIENVVIEDVQCSDILEEADVSENVIIPEQMLSSDVTEEVSLAHCTVPDDVLASDITSASMSMPEHVLTSESVHVSDVGHVEHIVHGSVVEAEIVTDPLTADVVSEEVLVADCASEAVIDANGIPVDQQDDDKGNCEDYLMISLDDDGKMEQDCSAGMTIDRESEIDPCKVDGTCPEVIKVYIFKADPGEDDLGGTVDIVESEPENDHGVELLDQNNSIRMPREKMVYMTVNDSQQEDEDLNVAEIADEVYMEVIVGEEDAAVAAAAATTVHEQEMDDSEIKTFMPIAWAAAYAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLTKKKYRCTDCDYTTNKKISLHNHLESHKLTSKSEKAIECDDCGKHFSHAGALFTHKMVHKEKGASKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGEKPYQCQYCEYRSADSSNLKTHVKTKHSKEMSFKCDICLLTFSDTKEVQQHALIHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKHVAAHKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCKKGFRQQNELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHITRHHKEVGLP", "length": 754, "header": "tr|A0ABI0P1E2-1|A0ABI0P1E2_BOVIN Computationally mapped isoform of Zinc finger protein, Y-linked OS=Bos taurus OX=9913 GN=ZFY PE=3 SV=1 CANONICAL=A0ABI0NNU4-1" }, "locus": { "chromosome": "Y", "start_pos": 8010896, "end_pos": 7989693, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148636.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148636.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105015.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105015.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNU4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNU4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNU4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNU4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNU4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNU4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNU4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNU4" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNU4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNU4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, 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"MDPTSLLPTLLNVDLTISHIECLPKDILVKFQGRNNIECEFDYHILQREIQHIQKGNNNVDIDDFCLVEERVSGEWQRGRVVEKKNELYTVLLIDRGEELRVDSTQVASACGNLFELPPRVTFGILANILPAGEKWSPKALNYFQSLVGLQVKGCVQAVLPLQMILLEVPNIISQVLELQLGRLIDGDSFRLIVEMVKEFPKQMPDSLHHKRPESSLSNNDTLLDIQHVLDNLQPSLSVGSTESVKVSSALSPSKFYCQLIKWIPELENFTTCMTLHYDIISQGSGPTCDNFGLLCAARRRNGQWHRGILQQLLPNNQVRIWFMDYGSTETVPSVLVKKLKQDFILVPLFSFPCSLTCLHSPDRDTRKFQLSIFKQALLGQVVCAHLDGFNKDEHLYYVTLETQESTISSKCLLKTVGTQVLCPVSDSKIYNRLRATSASEVNSFAVESFIANTKQSIDSLSKKDTLKIDFPVKTVEMKIEAAYIAFVVYVLNPSHFWVRTNEHQNEFQDIMKNINKYYDLCENDELILRNPEPGLFCCARYSKDRHFYRAVITEINGHKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHIFPVEDLWVKAAVDYFKKIVLNKEVLLQVIAKKDDKYTVNIQSIEASESSDIVSLMLQAGYAEYWEVEPECCPKFVSEYSVLNLKSKNKVKKVISALEGPQSKRYYSNKLKESNLSLLKFPPVNFSDFKNPFTLSLGPESPWRYKEYVFKPGTILEVKCSYSCGPGDFLCQLQCQLEDLKLLMEQLQHYYSVHSDPYQVGHMACVAKSSKDGKWYRAAILTQISKKEFDVVLVDYGYQERVLIRDLCAIKPHFLSLEAQAFRCSLNHLVEPISCKVLSWSREACRDFENFISSSRGLLTCVICAIVLIYPNCLSNLVDLQSPFTSAKEFLIRHGSVQYCTVSKPFPSSVSLYSYCYSSFNIKVGSEEEIYISHIYSPQKFYCQLSRNNKDLEMIETKIREISYLSDCPKYNFSKMRLCIAKYVEDGLSYRALSMPTDSLSDILVYFVDFGNKQLVEESMLRAVSDEFPELLFTPMQAIKCFLSDLSDVDIPAEINNWFADKYFGKPLRAKILSREPDGQFGVDLYDGYQHINQKIKMLLHAYGKKHCDQAQCVKKDHKTNENKKEAVALKGKIENNYHHNVSKTSLITYSESKTHQLMNPRSMYARLLKPSVCCKVEPVSKNKVKSLQDELKDVKIVPGLAHILDEHDVGQQSVKVVSQSFIRELNQAASKNIYSHARPQIKDLPQPKIYLNASVKGYVSNISNPASFHIQLAENENVIIRLAAALNTRRASIVRERISVKPMVGDLVVAEYSGDNAIYRAVIKKILSRNSYEVEFIDYGNTAIVSTSKIYEIKKEFLTIPQLGVHSFLSGVKWNEPNEIWDRKTVDYFASRVSNKTVSCEFLKRHEQKWEVNVICDEKCVINELVKWTACLKLQKTVLQMPQVVSQKVGPVDNEMKKGGSNGYEGSVILQPSYQQLVSIPFEELKPGQLEKAEILHVSKSGTFYVKLSKNKKILSDLTVLITKEVRNPDFLSVENIEKGLECLAKSKNTFQWYRSKVDKYVDEKVLVFLVDRGKYEIVPLCNTKVLSNEIRNIPRQAVPCKWIWFENFRKMPFESIVGLFAHLEIKILFLKYLDSAWKVDILIDGLLLLEYLNLNTVHVEENKFRSSGIICSIESKTPVSPCTIRSFTWTQLQNGRQYFGIATAVSDPSDFCVQLEDFFDTMKSLFMLLSDLPEDLQTVPQEHIIPGSGCLFKYESEDQWNRVEISEVSDQNLLLTLIDYGFSVYIHYSDIKNLKVVPEALLNLPRLSYPCILHGILPAEGRHWNEEAKRFFQDFLSKPGLVFQFREYSFETKLKVDIIHEKNNLADVLVASGLAIYSKDSAHLDAGFLKTPEGPQISD", "length": 1940, "header": "tr|A0ABI0NNW5-1|A0ABI0NNW5_BOVIN Isoform 1 of Tudor domain containing 15 OS=Bos taurus OX=9913 GN=TDRD15 PE=4 SV=1 CANONICAL=A0ABI0NNW5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NNW5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNW5/entry#A0ABI0NNW5-1", "sequence": { "sequence": "MDPTSLLPTLLNVDLTISHIECLPKDILVKFQGRNNIECEFDYHILQREIQHIQKGNNNVDIDDFCLVEERVSGEWQRGRVVEKKNELYTVLLIDRGEELRVDSTQVASACGNLFELPPRVTFGILANILPAGEKWSPKALNYFQSLVGLQVKGCVQAVLPLQMILLEVPNIISQVLELQLGRLIDGDSFRLIVEMVKEFPKQMPDSLHHKRPESSLSNNDTLLDIQHVLDNLQPSLSVGSTESVKVSSALSPSKFYCQLIKWIPELENFTTCMTLHYDIISQGSGPTCDNFGLLCAARRRNGQWHRGILQQLLPNNQVRIWFMDYGSTETVPSVLVKKLKQDFILVPLFSFPCSLTCLHSPDRDTRKFQLSIFKQALLGQVVCAHLDGFNKDEHLYYVTLETQESTISSKCLLKTVGTQVLCPVSDSKIYNRLRATSASEVNSFAVESFIANTKQSIDSLSKKDTLKIDFPVKTVEMKIEAAYIAFVVYVLNPSHFWVRTNEHQNEFQDIMKNINKYYDLCENDELILRNPEPGLFCCARYSKDRHFYRAVITEINGHKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHIFPVEDLWVKAAVDYFKKIVLNKEVLLQVIAKKDDKYTVNIQSIEASESSDIVSLMLQAGYAEYWEVEPECCPKFVSEYSVLNLKSKNKVKKVISALEGPQSKRYYSNKLKESNLSLLKFPPVNFSDFKNPFTLSLGPESPWRYKEYVFKPGTILEVKCSYSCGPGDFLCQLQCQLEDLKLLMEQLQHYYSVHSDPYQVGHMACVAKSSKDGKWYRAAILTQISKKEFDVVLVDYGYQERVLIRDLCAIKPHFLSLEAQAFRCSLNHLVEPISCKVLSWSREACRDFENFISSSRGLLTCVICAIVLIYPNCLSNLVDLQSPFTSAKEFLIRHGSVQYCTVSKPFPSSVSLYSYCYSSFNIKVGSEEEIYISHIYSPQKFYCQLSRNNKDLEMIETKIREISYLSDCPKYNFSKMRLCIAKYVEDGLSYRALSMPTDSLSDILVYFVDFGNKQLVEESMLRAVSDEFPELLFTPMQAIKCFLSDLSDVDIPAEINNWFADKYFGKPLRAKILSREPDGQFGVDLYDGYQHINQKIKMLLHAYGKKHCDQAQCVKKDHKTNENKKEAVALKGKIENNYHHNVSKTSLITYSESKTHQLMNPRSMYARLLKPSVCCKVEPVSKNKVKSLQDELKDVKIVPGLAHILDEHDVGQQSVKVVSQSFIRELNQAASKNIYSHARPQIKDLPQPKIYLNASVKGYVSNISNPASFHIQLAENENVIIRLAAALNTRRASIVRERISVKPMVGDLVVAEYSGDNAIYRAVIKKILSRNSYEVEFIDYGNTAIVSTSKIYEIKKEFLTIPQLGVHSFLSGVKWNEPNEIWDRKTVDYFASRVSNKTVSCEFLKRHEQKWEVNVICDEKCVINELVKWTACLKLQKTVLQMPQVVSQKVGPVDNEMKKGGSNGYEGSVILQPSYQQLVSIPFEELKPGQLEKAEILHVSKSGTFYVKLSKNKKILSDLTVLITKEVRNPDFLSVENIEKGLECLAKSKNTFQWYRSKVDKYVDEKVLVFLVDRGKYEIVPLCNTKVLSNEIRNIPRQAVPCKWIWFENFRKMPFESIVGLFAHLEIKILFLKYLDSAWKVDILIDGLLLLEYLNLNTVHVEENKFRSSGIICSIESKTPVSPCTIRSFTWTQLQNGRQYFGIATAVSDPSDFCVQLEDFFDTMKSLFMLLSDLPEDLQTVPQEHIIPGSGCLFKYESEDQWNRVEISEVSDQNLLLTLIDYGFSVYIHYSDIKNLKVVPEALLNLPRLSYPCILHGILPAEGRHWNEEAKRFFQDFLSKPGLVFQFREYSFETKLKVDIIHEKNNLADVLVASGLAIYSKDSAHLDAGFLKTPEGPQISD", "length": 1940, "header": "tr|A0ABI0NNW5-1|A0ABI0NNW5_BOVIN Isoform 1 of Tudor domain containing 15 OS=Bos taurus OX=9913 GN=TDRD15 PE=4 SV=1 CANONICAL=A0ABI0NNW5-1" }, "locus": { "chromosome": "11", "start_pos": 77808517, "end_pos": 77801965, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071214.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071214.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107478.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107478.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 288, "start_aa": "Thr", "end_pos": 288, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr288", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1011, "end_pos": 1013, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1180, "end_pos": 1182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1292, "end_pos": 1294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1301, "end_pos": 1303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1435, "end_pos": 1437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 714, "end_pos": 716, "annotation": "n_glycosylation_sequon" }, { "start_pos": 724, "end_pos": 726, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NNW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNW5" }, { "id": "PS50304", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50304" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tudor", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 117, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 288 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1011, "end_pos": 1013 }, { "start_pos": 1180, "end_pos": 1182 }, { "start_pos": 1292, "end_pos": 1294 }, { "start_pos": 1301, "end_pos": 1303 }, { "start_pos": 1435, "end_pos": 1437 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 714, "end_pos": 716 }, { "start_pos": 724, "end_pos": 726 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NNW6-1", "uniprot_ac": "A0ABI0NNW6", "uniprot_id": "A0ABI0NNW6_BOVIN", "mass": { "chemical_mass": 60992.0, "monoisotopic_mass": 60992.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NNW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNW6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May function as a transcription factor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNW6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNW6#function" }, { "database": "UniProtKB", "id": "ARBA00003729", "url": "https://www.uniprot.org/uniprotkb/ARBA00003729#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNW6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNW6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNW6", "locus": {} } ], "crossref": [ { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NNW6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNW6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAYFRAYHGNTKNLLCPFCLQIFKTEALYICHYRQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPG", "length": 543, "header": "tr|A0ABI0NNW6-1|A0ABI0NNW6_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NNW6-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NNW6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNW6/entry#A0ABI0NNW6-1", "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAYFRAYHGNTKNLLCPFCLQIFKTEALYICHYRQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPG", "length": 543, "header": "tr|A0ABI0NNW6-1|A0ABI0NNW6_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NNW6-1" }, "locus": { "chromosome": "Y", "start_pos": 44509788, "end_pos": 44508160, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137517.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137517.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107475.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107475.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNW6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNW6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNW6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNW6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNW6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNW6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NNW6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNW6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NNW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNW6" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 343, "end_pos": 371, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 68, 96 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 523, "end_pos": 525 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { 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] }, { "name": "2.7.11.13", "type": "synonym", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS30", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRKCA", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30", "locus": { "chromosome": "19", "start_pos": 62970305, "end_pos": 62936161, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001061", "url": "https://www.ensembl.org/id/ENSBTAG00000001061" } ] } } ], "crossref": [ { "id": "cd04026", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04026", 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{ "id": "IPR000961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017892", "database": "InterPro", 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NNX4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNX4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS30", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS30-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZP3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZP3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P018", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P018", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P018-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P018-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGGRAAPAARLGSASAGAAVRAERPQRARGSASAPRPPGSRPPSAAARAPRGRRRRGTMADVFPAAEPAAPQDVANRFARKGALRQKNVHEVKNHRFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPRWDESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVELRQKFEKAKLGPAGNKVISPSEDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV", "length": 731, "header": "tr|A0ABI0NS30-1|A0ABI0NS30_BOVIN Isoform 1 of Protein kinase C OS=Bos taurus OX=9913 GN=PRKCA PE=3 SV=1 CANONICAL=A0ABI0NS30-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NNX4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30/entry#A0ABI0NNX4-1", "sequence": { "sequence": "MRGGRAAPAARLGSASAGAAVRAERPQRARGSASAPRPPGSRPPSAAARAPRGRRRRGTMADVFPAAEPAAPQDVANRFARKGALRQKNVHEVKNHRFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPRWDESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVELRQKFEKAKLGPAGNKVISPSEDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVDPLGACSSPGLASANRGPKA", "length": 697, "header": "tr|A0ABI0NNX4-1|A0ABI0NS30_BOVIN Computationally mapped isoform of Protein kinase C OS=Bos taurus OX=9913 GN=PRKCA PE=3 SV=1 CANONICAL=A0ABI0NS30-1" }, "locus": { "chromosome": "19", "start_pos": 62956457, "end_pos": 62664468, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141497.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141497.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107590.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107590.1" } ] } }, { "isoform_ac": "A0ABI0NS30-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30/entry#A0ABI0NS30-1", "sequence": { "sequence": "MRGGRAAPAARLGSASAGAAVRAERPQRARGSASAPRPPGSRPPSAAARAPRGRRRRGTMADVFPAAEPAAPQDVANRFARKGALRQKNVHEVKNHRFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPRWDESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVELRQKFEKAKLGPAGNKVISPSEDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV", "length": 731, "header": "tr|A0ABI0NS30-1|A0ABI0NS30_BOVIN Isoform 1 of Protein kinase C OS=Bos taurus OX=9913 GN=PRKCA PE=3 SV=1 CANONICAL=A0ABI0NS30-1" }, "locus": { "chromosome": "19", "start_pos": 62969047, "end_pos": 62664468, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146774.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146774.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105644.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105644.1" } ] } }, { "isoform_ac": "A0ABI0NZP3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30/entry#A0ABI0NZP3-1", "sequence": { "sequence": "MRGGRAAPAARLGSASAGAAVRAERPQRARGSASAPRPPGSRPPSAAARAPRGRRRRGTMADVFPAAEPAAPQDVANRFARKGALRQKNVHEVKNHRFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPRWDESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVELRQKFEKAKLGPAGNKVISPSEDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVTFCTKTHWLQWASRPSVSTSWNLG", "length": 701, "header": "tr|A0ABI0NZP3-1|A0ABI0NZP3_BOVIN Computationally mapped isoform of Protein kinase C OS=Bos taurus OX=9913 GN=PRKCA PE=3 SV=1 CANONICAL=A0ABI0NS30-1" }, "locus": { "chromosome": "19", "start_pos": 62966331, "end_pos": 62664468, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148118.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148118.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104116.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104116.1" } ] } }, { "isoform_ac": "A0ABI0P018-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30/entry#A0ABI0P018-1", "sequence": { "sequence": "MRGGRAAPAARLGSASAGAAVRAERPQRARGSASAPRPPGSRPPSAAARAPRGRRRRGTMADVFPAAEPAAPQDVANRFARKGALRQKNVHEVKNHRFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPRWDESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVELRQKFEKAKLGPAGNKVISPSEDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVRGGDHGPQFTVQNTEAQRG", "length": 669, "header": "tr|A0ABI0P018-1|A0ABI0P018_BOVIN Computationally mapped isoform of Protein kinase C OS=Bos taurus OX=9913 GN=PRKCA PE=3 SV=1 CANONICAL=A0ABI0NS30-1" }, "locus": { "chromosome": "19", "start_pos": 62956705, "end_pos": 62664468, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150647.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150647.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104301.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104301.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS30", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS30", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ], "pmid": "" }, { "name": "diacylglycerol-dependent serine/threonine kinase activity", "id": "GO:0004697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004697", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS30", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS30", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS30", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS30", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS30", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS30", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS30", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 613, "end_pos": 615, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", 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"F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", 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"https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] } ] }, { "uniprot_ac": "Q4TVR5", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] } ] }, { "uniprot_ac": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] } ] }, { "uniprot_ac": "Q6TJY3", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] } ] }, { "uniprot_ac": "Q7YRC6", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] }, { "ec_number": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45728:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00289", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00289", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00364", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00364", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02785", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02785", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02786", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02786", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192262", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192262", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11308", "url": "https://www.rhea-db.org/rhea/11308", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NPB9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPB9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPZ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0Y1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDSKQVTKSKRKVSFTPSQEPIPASEGSQEPPQEDCNSSPLPKTPSQAELASHKGPQDTCQQRPSQSPLPQNPQGNPLSSDDASPARQANGSETEGPEIPNTNDLSAPARPQGQRARTLSREDRKQAHIKRQLMTNFILGSFDDNSSDEDAGAALFRQSSRKGSRASLGTLSLETAHAAGETETCAPVIRPSMSGLHLARRGREQKKVDLHRDFTVASPAEFVTRFAGHLVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLRKHEIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWNGSGLTVEWAEHSLQEGQRISIPESVYNNGCVKDVDEGLEAAEKIGFPLMIKASEGGGGKGIRKAETAEDFPILFRQVQSETPGSPVFLMKLAQRARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPAVFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPIPRGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLTNLLETENFQNNDIDTSWLDNLIAEKVQAEKPDIMLGVVCGALNVADSMFRTCMTDFLHSLERGQVLPADSLLNIVDVELIYGGVKYILKVARQSPTMFVLIMNGSHIEIDAHRLNDGGLLLSCSGNSYTTYLKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLVKYTVADGEHVEAGGSYAEIEVMKMTTTLNVQESGRVKYVRRPGAVLEAGCVVARLELDDPSKVRPAEPFTGELPSQPTLPILGEKLHQVFHSVLENLTNIMNGYCLPEPIFSIKLKDWVQKLLRALRHPSLPLLELQEIMTSVSGRVPAPVEKAVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFMNTQSIVQLVQKYRSGARGYMKAVVLDLLRRYLLVEHHFQQAHYDKCVINLREQLKPDMAQVLDCIFSHSQVAKKNQLVIMLIDELCGPDPSLSDELTSILDELTQLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELTSLQHRQFPDGTCVVEFQFMLPSSHPHRMTVPISVTNPELLRHSTELFMDSGFSPKSQRMGAMVAFQRFEDFVRNFDEVISCFANMPKDTPLFSEARNSLYSEDDSKSLREEPIHILNVALQHADHQEDEQLVPIFRTFVQSKKNILVECGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRLRNFDVTAMPCANHKMHLYLGAARVKEGAEVTDHRFFIRVIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAEVKINIRQTTADSAIPIRLFITNESGYYLDISLYKEVTDPRSGNILFHSFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKMWPSPDKYPKDILTYTELVLDPQGQLVEMNRLPGGNEVGMVAFKMTLKTLEYPEGRDIILISNDITFRIGSFGPGEDLLYLRASELARAEGIPRVYLAANSGARIGLAEEIKHMFQVAWVDPEDPHKGIKYLYLTPQDYTRISSLNSVHCKHVEEDGESRYVITDIIGKEEGLGVENLRGSGMIAGETSQDYDEIVTISMVSCRALGIGAYLVRLGQRVIQVENSHIILTGATALNKVLGRDVYTSNNQLGGVQIMHHNGVSHVTVPDDFEGVCTILEWLSYMPKDNRSPVPVVTPKDPIDREIEFQPSRGPYDPRWLLAGRPHPTLKGSWQSGFFDQGSFKEIMVPWAQTVVTGRARLGGIPVGVIAAETRTVELVVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNREKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRKYRQPVLIYIPPYAEVRGGSWAVMDTSINPLCIEMYADRESRASVLEPEGTVEIKYQKKDLVKTIRRLDPISKKLVEQLGVSELSDTDRKELEGQLKAREDLLLPMYHQVALHFADLHDTAGRMLEKGVIYDILEWKTARSFLYWRLRRLLLESQVKQEVLRACPELSHMHVQSMLRRWFVETEGAVKAYLWDNNQTVVQWLEAHGQASEGLHSTIRENITCLRRDSALKTIQGLVQENPELAMDSLVYVSQHISPAERAQVIHLLSTTDGPAST", "length": 2431, "header": "tr|A0ABI0NPZ4-1|A0ABI0NPZ4_BOVIN Isoform 1 of Acetyl-CoA carboxylase 1 OS=Bos taurus OX=9913 GN=ACACB PE=4 SV=1 CANONICAL=A0ABI0NPZ4-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NPB9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ4/entry#A0ABI0NPB9-1", "sequence": { "sequence": "MHALRPKSSLVSGRTVNMSPAKCKVCSPDRKVKPSMSGLHLARRGREQKKVDLHRDFTVASPAEFVTRFAGHLVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLRKHEIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWNGSGLTVEWAEHSLQEGQRISIPESVYNNGCVKDVDEGLEAAEKIGFPLMIKASEGGGGKGIRKAETAEDFPILFRQVQSETPGSPVFLMKLAQRARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPAVFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPIPRGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLTNLLETENFQNNDIDTSWLDNLIAEKVQAEKPDIMLGVVCGALNVADSMFRTCMTDFLHSLERGQVLPADSLLNIVDVELIYGGVKYILKVARQSPTMFVLIMNGSHIEIDAHRLNDGGLLLSCSGNSYTTYLKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLVKYTVADGEHVEAGGSYAEIEVMKMTTTLNVQESGRVKYVRRPGAVLEAGCVVARLELDDPSKVRPAEPFTGELPSQPTLPILGEKLHQVFHSVLENLTNIMNGYCLPEPIFSIKLKDWVQKLLRALRHPSLPLLELQEIMTSVSGRVPAPVEKAVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFMNTQSIVQLVQKYRSGARGYMKAVVLDLLRRYLLVEHHFQQAHYDKCVINLREQLKPDMAQVLDCIFSHSQVAKKNQLVIMLIDELCGPDPSLSDELTSILDELTQLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKVYVRRGYIAYELTSLQHRQFPDGTCVVEFQFMLPSSHPHRMTVPISVTNPELLRHSTELFMDSGFSPKSQRMGAMVAFQRFEDFVRNFDEVISCFANMPKDTPLFSEARNSLYSEDDSKSLREEPIHILNVALQHADHQEDEQLVPIFRTFVQSKKNILVECGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRLRNFDVTAMPCANHKMHLYLGAARVKEGAEVTDHRFFIRVIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAEVKINIRQTTADSAIPIRLFITNESGYYLDISLYKEVTDPRSGNILFHSFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKMWPSPDKYPKDILTYTELVLDPQGQLVEMNRLPGGNEVGMVAFKMTLKTLEYPEGRDIILISNDITFRIGSFGPGEDLLYLRASELARAEGIPRVYLAANSGARIGLAEEIKHMFQVAWVDPEDPHKGIKYLYLTPQDYTRISSLNSVHCKHVEEDGESRYVITDIIGKEEGLGVENLRGSGMIAGETSQDYDEIVTISMVSCRALGIGAYLVRLGQRVIQVENSHIILTGATALNKVLGRDVYTSNNQLGGVQIMHHNGVSHVTVPDDFEGVCTILEWLSYMPKDNRSPVPVVTPKDPIDREIEFQPSRGPYDPRWLLAGRPHPTLKGSWQSGFFDQGSFKEIMVPWAQTVVTGRARLGGIPVGVIAAETRTVELVVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNREKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRKYRQPVLIYIPPYAEVRGGSWAVMDTSINPLCIEMYADRESRASVLEPEGTVEIKYQKKDLVKTIRRLDPISKKLVEQLGVSELSDTDRKELEGQLKAREDLLLPMYHQVALHFADLHDTAGRMLEKGVIYDILEWKTARSFLYWRLRRLLLESQVKQEVLRACPELSHMHVQSMLRRWFVETEGAVKAYLWDNNQTVVQWLEAHGQASEGLHSTIRENITCLRRDSALKTIQGLVQENPELAMDSLVYVSQHISPAERAQVIHLLSTTDGPAST", "length": 2243, "header": "tr|A0ABI0NPB9-1|A0ABI0NPZ4_BOVIN Computationally mapped isoform of Acetyl-CoA carboxylase 1 OS=Bos taurus OX=9913 GN=ACACB PE=4 SV=1 CANONICAL=A0ABI0NPZ4-1" }, "locus": { "chromosome": "17", "start_pos": 63929872, "end_pos": 63847014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146794.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146794.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104869.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104869.1" } ] } }, { "isoform_ac": "A0ABI0NPZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ4/entry#A0ABI0NPZ4-1", "sequence": { "sequence": "MSDSKQVTKSKRKVSFTPSQEPIPASEGSQEPPQEDCNSSPLPKTPSQAELASHKGPQDTCQQRPSQSPLPQNPQGNPLSSDDASPARQANGSETEGPEIPNTNDLSAPARPQGQRARTLSREDRKQAHIKRQLMTNFILGSFDDNSSDEDAGAALFRQSSRKGSRASLGTLSLETAHAAGETETCAPVIRPSMSGLHLARRGREQKKVDLHRDFTVASPAEFVTRFAGHLVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLRKHEIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWNGSGLTVEWAEHSLQEGQRISIPESVYNNGCVKDVDEGLEAAEKIGFPLMIKASEGGGGKGIRKAETAEDFPILFRQVQSETPGSPVFLMKLAQRARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPAVFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPIPRGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLTNLLETENFQNNDIDTSWLDNLIAEKVQAEKPDIMLGVVCGALNVADSMFRTCMTDFLHSLERGQVLPADSLLNIVDVELIYGGVKYILKVARQSPTMFVLIMNGSHIEIDAHRLNDGGLLLSCSGNSYTTYLKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLVKYTVADGEHVEAGGSYAEIEVMKMTTTLNVQESGRVKYVRRPGAVLEAGCVVARLELDDPSKVRPAEPFTGELPSQPTLPILGEKLHQVFHSVLENLTNIMNGYCLPEPIFSIKLKDWVQKLLRALRHPSLPLLELQEIMTSVSGRVPAPVEKAVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFMNTQSIVQLVQKYRSGARGYMKAVVLDLLRRYLLVEHHFQQAHYDKCVINLREQLKPDMAQVLDCIFSHSQVAKKNQLVIMLIDELCGPDPSLSDELTSILDELTQLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELTSLQHRQFPDGTCVVEFQFMLPSSHPHRMTVPISVTNPELLRHSTELFMDSGFSPKSQRMGAMVAFQRFEDFVRNFDEVISCFANMPKDTPLFSEARNSLYSEDDSKSLREEPIHILNVALQHADHQEDEQLVPIFRTFVQSKKNILVECGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRLRNFDVTAMPCANHKMHLYLGAARVKEGAEVTDHRFFIRVIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAEVKINIRQTTADSAIPIRLFITNESGYYLDISLYKEVTDPRSGNILFHSFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKMWPSPDKYPKDILTYTELVLDPQGQLVEMNRLPGGNEVGMVAFKMTLKTLEYPEGRDIILISNDITFRIGSFGPGEDLLYLRASELARAEGIPRVYLAANSGARIGLAEEIKHMFQVAWVDPEDPHKGIKYLYLTPQDYTRISSLNSVHCKHVEEDGESRYVITDIIGKEEGLGVENLRGSGMIAGETSQDYDEIVTISMVSCRALGIGAYLVRLGQRVIQVENSHIILTGATALNKVLGRDVYTSNNQLGGVQIMHHNGVSHVTVPDDFEGVCTILEWLSYMPKDNRSPVPVVTPKDPIDREIEFQPSRGPYDPRWLLAGRPHPTLKGSWQSGFFDQGSFKEIMVPWAQTVVTGRARLGGIPVGVIAAETRTVELVVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNREKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRKYRQPVLIYIPPYAEVRGGSWAVMDTSINPLCIEMYADRESRASVLEPEGTVEIKYQKKDLVKTIRRLDPISKKLVEQLGVSELSDTDRKELEGQLKAREDLLLPMYHQVALHFADLHDTAGRMLEKGVIYDILEWKTARSFLYWRLRRLLLESQVKQEVLRACPELSHMHVQSMLRRWFVETEGAVKAYLWDNNQTVVQWLEAHGQASEGLHSTIRENITCLRRDSALKTIQGLVQENPELAMDSLVYVSQHISPAERAQVIHLLSTTDGPAST", "length": 2431, "header": "tr|A0ABI0NPZ4-1|A0ABI0NPZ4_BOVIN Isoform 1 of Acetyl-CoA carboxylase 1 OS=Bos taurus OX=9913 GN=ACACB PE=4 SV=1 CANONICAL=A0ABI0NPZ4-1" }, "locus": { "chromosome": "17", "start_pos": 63943258, "end_pos": 63847014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154197.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154197.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105259.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105259.1" } ] } }, { "isoform_ac": "A0ABI0P0Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ4/entry#A0ABI0P0Y1-1", "sequence": { "sequence": "MHALRPKSSLVSGRTVNMSPAKCKVCSPDRKVKPSMSGLHLARRGREQKKVDLHRDFTVASPAEFVTRFAGHLVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLRKHEIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWNGSGLTVEWAEHSLQEGQRISIPESVYNNGCVKDVDEGLEAAEKIGFPLMIKASEGGGGKGIRKAETAEDFPILFRQVQSETPGSPVFLMKLAQRARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPAVFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPIPRGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLTNLLETENFQNNDIDTSWLDNLIAEKVQAEKPDIMLGVVCGALNVADSMFRTCMTDFLHSLERGQVLPADSLLNIVDVELIYGGVKYILKVARQSPTMFVLIMNGSHIEIDAHRLNDGGLLLSCSGNSYTTYLKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLVKYTVADGEHVEAGGSYAEIEVMKMTTTLNVQESGRVKYVRRPGAVLEAGCVVARLELDDPSKVRPAEPFTGELPSQPTLPILGEKLHQVFHSVLENLTNIMNGYCLPEPIFSIKLKDWVQKLLRALRHPSLPLLELQEIMTSVSGRVPAPVEKAVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFMNTQSIVQLVQKYRSGARGYMKAVVLDLLRRYLLVEHHFQQAHYDKCVINLREQLKPDMAQVLDCIFSHSQVAKKNQLVIMLIDELCGPDPSLSDELTSILDELTQLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELTSLQHRQFPDGTCVVEFQFMLPSSHPHRMTVPISVTNPELLRHSTELFMDSGFSPKSQRMGAMVAFQRFEDFVRNFDEVISCFANMPKDTPLFSEARNSLYSEDDSKSLREEPIHILNVALQHADHQEDEQLVPIFRTFVQSKKNILVECGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRLRNFDVTAMPCANHKMHLYLGAARVKEGAEVTDHRFFIRVIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAEVKINIRQTTADSAIPIRLFITNESGYYLDISLYKEVTDPRSGNILFHSFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKMWPSPDKYPKDILTYTELVLDPQGQLVEMNRLPGGNEVGMVAFKMTLKTLEYPEGRDIILISNDITFRIGSFGPGEDLLYLRASELARAEGIPRVYLAANSGARIGLAEEIKHMFQVAWVDPEDPHKGIKYLYLTPQDYTRISSLNSVHCKHVEEDGESRYVITDIIGKEEGLGVENLRGSGMIAGETSQDYDEIVTISMVSCRALGIGAYLVRLGQRVIQVENSHIILTGATALNKVLGRDVYTSNNQLGGVQIMHHNGVSHVTVPDDFEGVCTILEWLSYMPKDNRSPVPVVTPKDPIDREIEFQPSRGPYDPRWLLAGRPHPTLKGSWQSGFFDQGSFKEIMVPWAQTVVTGRARLGGIPVGVIAAETRTVELVVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNREKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRKYRQPVLIYIPPYAEVRGGSWAVMDTSINPLCIEMYADRESRASVLEPEGTVEIKYQKKDLVKTIRRLDPISKKLVEQLGVSELSDTDRKELEGQLKAREDLLLPMYHQVALHFADLHDTAGRMLEKGVIYDILEWKTARSFLYWRLRRLLLESQVKQEVLRACPELSHMHVQSMLRRWFVETEGAVKAYLWDNNQTVVQWLEAHGQASEGLHSTIRENITCLRRDSALKTIQGLVQENPELAMDSLVYVSQHISPAERAQVIHLLSTTDGPAST", "length": 2273, "header": "tr|A0ABI0P0Y1-1|A0ABI0P0Y1_BOVIN Computationally mapped isoform of Acetyl-CoA carboxylase 1 OS=Bos taurus OX=9913 GN=ACACB PE=4 SV=1 CANONICAL=A0ABI0NPZ4-1" }, "locus": { "chromosome": "17", "start_pos": 63929872, "end_pos": 63847014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139246.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139246.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104100.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104100.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Genetic association of the ACACB gene with milk yield and composition traits in dairy cattle.", "journal": "Animal genetics", "date": "2018-06", "authors": "Han B, Liang W, Liu L, Li Y, Sun D", "evidence": [ { "database": "RefSeq", "id": "NP_001192262", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192262" } ], "reference": [ { "type": "PubMed", "id": "29521460", "url": "https://glygen.org/publication/PubMed/29521460" } ] } ], "pathway": [ { "id": "bta:515338", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515338", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPZ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPZ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPZ4" } ], "pmid": "" }, { "name": "acetyl-CoA carboxylase activity", "id": "GO:0003989", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003989", "evidence": [ { "database": "UniProtKB", "id": 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[provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377554" }, "gene_names": [ { "name": "OR13C1", "type": "recommended", "evidence": [ { "id": "A0ABI0NPW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPW3" } ] }, { "name": "OR13C1", "type": "synonym", "evidence": [ { "id": "NP_001377554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377554" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NPW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPW3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 13 subfamily C member 1", "type": "synonym", "evidence": [ { "id": "NP_001377554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377554" } ] }, { "name": "putative olfactory receptor ENSP00000348552-like", "type": "synonym", "evidence": [ { "id": "NP_001377554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377554" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPW3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPW3#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQ05-1", "uniprot_ac": "A0ABI0NQ05", "uniprot_id": "A0ABI0NQ05_BOVIN", "mass": { "chemical_mass": 35542.0, "monoisotopic_mass": 35542.0 }, "refseq": { "ac": "NP_001377617", "name": "olfactory receptor family 5 subfamily AL member 2", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377617" }, "gene_names": [ { "name": "OR5AL2", "type": "recommended", "evidence": [ { "id": "A0ABI0NQ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ05" } ] }, { "name": "OR5AL2", "type": "synonym", "evidence": [ { "id": "NP_001377617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377617" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NQ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ05/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5AL1", "type": "synonym", "evidence": [ { "id": "NP_001377617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377617" } ] }, { "name": "olfactory receptor family 5 subfamily AL member 2", "type": "synonym", "evidence": [ { "id": "NP_001377617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377617" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377617", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377617" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ05", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ05#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ05", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ05" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR5AL2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ05", "locus": {} } ], "crossref": [ { "id": "100300575", "url": 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], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQ32-1", "uniprot_ac": "A0ABI0NQ32", "uniprot_id": "A0ABI0NQ32_BOVIN", "mass": { "chemical_mass": 10706.0, "monoisotopic_mass": 10706.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Small nuclear ribonucleoprotein E", "type": "recommended", "evidence": [ { "id": "A0ABI0NQ32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ32/entry#names_and_taxonomy" } ] }, { "name": "Sm protein E", "type": "synonym", "evidence": [ { "id": "A0ABI0NQ32", "database": "UniProtKB", "url": 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Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. 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"database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11193", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11193", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NQ32", 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"name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ32", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ32" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ32", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ32" } ], "pmid": "" }, { "name": "U4 snRNP", "id": "GO:0005687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005687", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ32", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ32" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ32", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ32" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ32", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ32" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ32", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ32" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ32", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" 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{ "uniprot_canonical_ac": "A0ABI0NQ36-1", "uniprot_ac": "A0ABI0NQ36", "uniprot_id": "A0ABI0NQ36_BOVIN", "mass": { "chemical_mass": 50760.0, "monoisotopic_mass": 50760.0 }, "refseq": {}, "gene_names": [ { "name": "DLC1", "type": "recommended", "evidence": [ { "id": "A0ABI0NQ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ36" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 7", "type": "synonym", "evidence": [ { "id": "A0ABI0NQ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ36/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ36" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DLC1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ36", "locus": { "chromosome": "27", "start_pos": 23915890, "end_pos": 23846914, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015541", "url": "https://www.ensembl.org/id/ENSBTAG00000015541" } ] } } ], "crossref": [ { "id": "A0ABI0NQ36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ36-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ36-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVAIRKRSWEEHVTQWMGQPFSSDDCNTACHHGLVADSLQASMEKDATLNVDRKERCVSLPDCCHGSDLREIPEGPMGHISKEVDEDDSHEGEDQFLSLEASTETLVHVSDEDTDSDLYLTDDKQILTTQGPETSDQHSVKGAGSLVKTLPIVESNQDSYDSWGMAGGVDLGLVEEKGDKKVVDMVSKSLELCKEISLSEIKDRSKMNACSSLNVKDIVPEKQLVNSAVIAQHRRKPDFPKDEHESNTCSAVQDKLLAIPRMDRGLPLLKTDPGSCLLQPPSCPSGMSAENGLETSGFSEHQNKSLPKFNSGDGMQCLHFKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIMKLDQLDQDIENALSSSSSPSSTPTSLRRQVPDLESGPESGTDTTSINQTQVNLSSNTESTDPQSSTPVANSGTKPKSMAIPGLSEKEKAGKLTWFCFHSYPL", "length": 462, "header": "tr|A0ABI0NQ36-1|A0ABI0NQ36_BOVIN Isoform 1 of Rho GTPase-activating protein 7 OS=Bos taurus OX=9913 GN=DLC1 PE=4 SV=1 CANONICAL=A0ABI0NQ36-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NQ36-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ36/entry#A0ABI0NQ36-1", "sequence": { "sequence": "MSVAIRKRSWEEHVTQWMGQPFSSDDCNTACHHGLVADSLQASMEKDATLNVDRKERCVSLPDCCHGSDLREIPEGPMGHISKEVDEDDSHEGEDQFLSLEASTETLVHVSDEDTDSDLYLTDDKQILTTQGPETSDQHSVKGAGSLVKTLPIVESNQDSYDSWGMAGGVDLGLVEEKGDKKVVDMVSKSLELCKEISLSEIKDRSKMNACSSLNVKDIVPEKQLVNSAVIAQHRRKPDFPKDEHESNTCSAVQDKLLAIPRMDRGLPLLKTDPGSCLLQPPSCPSGMSAENGLETSGFSEHQNKSLPKFNSGDGMQCLHFKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIMKLDQLDQDIENALSSSSSPSSTPTSLRRQVPDLESGPESGTDTTSINQTQVNLSSNTESTDPQSSTPVANSGTKPKSMAIPGLSEKEKAGKLTWFCFHSYPL", "length": 462, "header": "tr|A0ABI0NQ36-1|A0ABI0NQ36_BOVIN Isoform 1 of Rho GTPase-activating protein 7 OS=Bos taurus OX=9913 GN=DLC1 PE=4 SV=1 CANONICAL=A0ABI0NQ36-1" }, "locus": { "chromosome": "27", "start_pos": 23702166, "end_pos": 23492102, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147551.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147551.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105382.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105382.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 304, "end_pos": 306 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 412, "end_pos": 414 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQ39-1", "uniprot_ac": "A0ABI0NQ39", "uniprot_id": "A0ABI0NQ39_BOVIN", "mass": { "chemical_mass": 53306.0, "monoisotopic_mass": 53306.0 }, "refseq": { "ac": "XP_059748352", "name": "syncytin-Rum1 precursor", "summary": "Many different endogenous retrovirus families are expressed in normal placental tissue at high levels, suggesting that endogenous retroviruses are functionally important in reproduction. This gene is part of a bovine endogenous retrovirus provirus that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. [provided by RefSeq, Apr 2015].", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059748352" }, "gene_names": [ { "name": "RUM1", "type": "recommended", "evidence": [ { "id": "A0ABI0NQ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ39" } ] }, { "name": "RUM1", "type": "synonym", "evidence": [ { "id": "XP_059748352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059748352" } ] } ], "protein_names": [ { "name": "Syncytin-Rum1", "type": "synonym", "evidence": [ { "id": "A0ABI0NQ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ39/entry#names_and_taxonomy" } ] }, { "name": "endogenous retrovirus group PABLB member 1 Env polyprotein-like", "type": "synonym", "evidence": [ { "id": "XP_059748352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059748352" } ] }, { "name": "syncytin-Rum1 precursor", "type": "synonym", "evidence": [ { "id": "XP_059748352", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059748352" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ39", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ39" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RUM1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ39", "locus": {} } ], "crossref": [ { "id": "104973909", "url": "https://www.ncbi.nlm.nih.gov/gene/104973909", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10424", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10424", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10424:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10424:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059748352", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059748352", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ39", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ39-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELGKRLLLLGFTNAILNLTTVPVQGNIFISWAHSYANFHNSSNCWVCGAMPLSVMDGLPWWVSPLHDGDFLPLCSFLEQQKGTFISLSNHDLSLLPWCKKEPSMGLGHGVTFSMNASLKALTSAYNSYMSNGQKNSTPTKEEQTFRYHEVYYQVWDEYFWMTSERGQVITRATICWEQKEHKIGFGDHPLNPKDLKYMGYLSAEQCKQILDVTYHPSRSAQWPGSDWKYSPGIRWVAPNGTKWLCGPNLWPWLPVGWVGRCTLGFVFAPGRIKPSLHHPPANLPYLHARWTRSTFQWYDYLAGFFVPSIGTADIMVKVEALNNFTKQALLDSKKAIEALNEEQSQMRKAVMQNRMALDILTAAQGGTCAIIKVECCVYIPDLSGNVSAAMEDMQKQVKAMSGENIPFWTLILSWVKGDWWKTIVNVVIVFLMILVCGPCLLQCLVNFVTQRLVAFSHVVAHRTNVQSTSK", "length": 471, "header": "tr|A0ABI0NQ39-1|A0ABI0NQ39_BOVIN Isoform 1 of Syncytin-Rum1 OS=Bos taurus OX=9913 GN=RUM1 PE=4 SV=1 CANONICAL=A0ABI0NQ39-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NQ39-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ39/entry#A0ABI0NQ39-1", "sequence": { "sequence": 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"tr|A0ABI0NQ43-1|A0ABI0NQ43_BOVIN Isoform 1 of Immunoglobulin V-set domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NQ43-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NQ43-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ43/entry#A0ABI0NQ43-1", "sequence": { "sequence": "MDTEVTQSPSHLLKGKDQRAKMDCVPKKGHSYVYWYHKKLEEALENTAMFKQRFSAECPQNSPCSLEINSTEAADSALCFCASSQSTVLRVSSS", "length": 94, "header": "tr|A0ABI0NQ43-1|A0ABI0NQ43_BOVIN Isoform 1 of Immunoglobulin V-set domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NQ43-1" }, "locus": { "chromosome": "4", "start_pos": 105994055, "end_pos": 105993739, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149763.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149763.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105336.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105336.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ43", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NQ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ43" }, { "id": "PF07686", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Immunoglobulin V-set", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 84, "start_aa": "Gln", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQ53-1", "uniprot_ac": "A0ABI0NQ53", "uniprot_id": "A0ABI0NQ53_BOVIN", "mass": { "chemical_mass": 28111.0, "monoisotopic_mass": 28111.0 }, "refseq": { "ac": "XP_024832803", "name": "glycolipid transfer protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832803" }, "gene_names": [ { "name": "GLTP", "type": "recommended", "evidence": [ { "id": "A0ABI0NQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ53" } ] }, { "name": "GLTP", "type": "synonym", "evidence": [ { "id": "XP_024832803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832803" } ] } ], "protein_names": [ { "name": "Glycolipid transfer protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ53/entry#names_and_taxonomy" } ] }, { "name": "glycolipid transfer protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024832803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832803" } ] } ], "function": [ { "annotation": "Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.", "evidence": [ { "database": "UniProtKB", "id": "F6RTN4", "url": "https://www.uniprot.org/uniprotkb/F6RTN4#function" }, { "database": "UniProtKB", "id": "ARBA00037246", "url": "https://www.uniprot.org/uniprotkb/ARBA00037246#function" }, { "database": "UniProtKB", "id": "A0ABI0NQ53", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ53#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ53", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ53" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GLTP", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ53", "locus": { "chromosome": "17", "start_pos": 63399500, "end_pos": 63377041, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002591", "url": "https://www.ensembl.org/id/ENSBTAG00000002591" } ] } } ], "crossref": [ { "id": "ENSBTAG00000002591", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002591", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "327678", "url": "https://www.ncbi.nlm.nih.gov/gene/327678", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014830", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014830", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036497", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036497", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EMHGAEW", "url": "https://omabrowser.org/oma/group/EMHGAEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10219:SF97", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10219:SF97", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08718", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08718", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024832803", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832803", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ53", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ53-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RTN4", "url": "https://www.uniprot.org/uniprotkb/F6RTN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RTN4-1", "url": "https://www.uniprot.org/uniprotkb/F6RTN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLAEHLLRPLPADKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGNITKIKAVYDTNPTKFRTLQNILEVEKEMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRVNATKAYEMALKKYHGWIVQKIFQADSLPAEPQGKPKNTGVGSLSLRQGIFLTQELNWDLLHCRRILYQLSYQGSQIRYKYTHIPSLLSLPPFHPHPPPLLKLVLLSLFIQLHCFPSSSEML", "length": 247, "header": "tr|A0ABI0NQ53-1|A0ABI0NQ53_BOVIN Isoform 1 of Glycolipid transfer protein OS=Bos taurus OX=9913 GN=GLTP PE=3 SV=1 CANONICAL=A0ABI0NQ53-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NQ53-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ53/entry#A0ABI0NQ53-1", "sequence": { "sequence": "MALLAEHLLRPLPADKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGNITKIKAVYDTNPTKFRTLQNILEVEKEMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRVNATKAYEMALKKYHGWIVQKIFQADSLPAEPQGKPKNTGVGSLSLRQGIFLTQELNWDLLHCRRILYQLSYQGSQIRYKYTHIPSLLSLPPFHPHPPPLLKLVLLSLFIQLHCFPSSSEML", "length": 247, "header": "tr|A0ABI0NQ53-1|A0ABI0NQ53_BOVIN Isoform 1 of Glycolipid transfer protein OS=Bos taurus OX=9913 GN=GLTP PE=3 SV=1 CANONICAL=A0ABI0NQ53-1" }, "locus": { "chromosome": "17", "start_pos": 63397713, "end_pos": 63377156, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154887.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154887.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104317.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104317.1" } ] } }, { "isoform_ac": "F6RTN4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ53/entry#F6RTN4-1", "sequence": { "sequence": "MQLECSRWLARCAGSPWVEFSPQVALLQSSAPVQPADCLGSPVFTPIKADISGNITKIKAVYDTNPTKFRTLQNILEVEKEMYGAEWPKVGATLALMWLKRGLRFIQVFLQSICDGERDENHPNLIRVNATKAYEMALKKYHGWIVQKIFQAALYAAPYKSDFLKALSKGQNVTEEECLEKIRLFLVNYTATIDVIYEMYTRMNAELNYKV", "length": 211, "header": "tr|F6RTN4-1|F6RTN4_BOVIN Computationally mapped isoform of Glycolipid transfer protein OS=Bos taurus OX=9913 GN=GLTP PE=3 SV=1 CANONICAL=A0ABI0NQ53-1" }, "locus": { "chromosome": "17", "start_pos": 63398507, "end_pos": 63390468, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003355.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003355.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003355.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003355.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ53", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ53" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipid transfer activity", "id": "GO:0120013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120013", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ53", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ53" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ53" }, { "id": "PF08718", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08718" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycolipid transfer protein", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 150, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQ70-1", "uniprot_ac": "A0ABI0NQ70", "uniprot_id": "A0ABI0NQ70_BOVIN", "mass": { "chemical_mass": 36398.0, "monoisotopic_mass": 36398.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Testis-specific Y-encoded protein 1", "type": "recommended", "evidence": [ { "id": "A0ABI0NQ70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ70/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ70", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ70" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ70", "locus": {} } ], "crossref": [ { "id": "IPR002164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11875", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11875", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00956", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00956", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NQ70", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ70-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRPFASAPARGHRQGQEERERRSEEGGSVPGPRTFQVVSPVVTPGQEATLFRVEAVEEGEALVDGDVAGIGREFQLLAEDIVEEVEVVADEEQEQRPSQELEEKTVEEQGQERPGGPCECQELDALQALAALQVELSSEREQNRRAYVQFMRKNHQRRKRHLARRSAIIQGIPGFWAKAIMSHPQVSVLISDQDQDFLGYMMDLKVQVRSHPPSRCKLIFSFRDNPYFLNSVIIKEYYLDITGYRARRSTPVHWFWDFERGAPSRRLDTRSLNFLNWLSGHNGPESNRIAEIISEDVWDDPLKYYLREEGSSVRDN", "length": 317, "header": "tr|A0ABI0NQ70-1|A0ABI0NQ70_BOVIN Isoform 1 of Testis-specific Y-encoded protein 1 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NQ70-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NQ70-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ70/entry#A0ABI0NQ70-1", "sequence": { "sequence": "MSRPFASAPARGHRQGQEERERRSEEGGSVPGPRTFQVVSPVVTPGQEATLFRVEAVEEGEALVDGDVAGIGREFQLLAEDIVEEVEVVADEEQEQRPSQELEEKTVEEQGQERPGGPCECQELDALQALAALQVELSSEREQNRRAYVQFMRKNHQRRKRHLARRSAIIQGIPGFWAKAIMSHPQVSVLISDQDQDFLGYMMDLKVQVRSHPPSRCKLIFSFRDNPYFLNSVIIKEYYLDITGYRARRSTPVHWFWDFERGAPSRRLDTRSLNFLNWLSGHNGPESNRIAEIISEDVWDDPLKYYLREEGSSVRDN", "length": 317, "header": "tr|A0ABI0NQ70-1|A0ABI0NQ70_BOVIN Isoform 1 of Testis-specific Y-encoded protein 1 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NQ70-1" }, "locus": { "chromosome": "Y", "start_pos": 9503439, "end_pos": 9501202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138038.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138038.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104315.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104315.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 44, "start_aa": "Thr", "end_pos": 44, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr44", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ70", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ70" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ70", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 44 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQ81-1", "uniprot_ac": "A0ABI0NQ81", "uniprot_id": "A0ABI0NQ81_BOVIN", "mass": { "chemical_mass": 86265.0, "monoisotopic_mass": 86265.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RZ-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NQ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ81/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ81" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ81", "locus": {} } ], "crossref": [ { "id": "IPR031248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22605", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22605", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22605:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22605:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20173", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20173", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NQ81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ81-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYQVSISKLAEFKISGNMLGSSSPRHYLVRPESRELGLPFNGGSLGKASPANIVSCSFNSMSNGHVCSVGECGKPMEQSFCIDCRAPIGGINHKPEERFRVIDDTTDRTQTGHVLGNPPPRGAPVVSDRQMSPVVFLLIRLLTHLAMLLGATQSPQDLMNIIKPPVSDPKRFLQQHIQRDLEQLMNTLGRSADETASVVHLVLCRLLQEQSHSSSDFDAELSTREERNRWEKLVETIILHELEYLDKTLLAVNAQISQDERISSNPVAKIVYGDPATFLPHLPKNSMVHCSKMWSCRKRITIEYLQHIVEQKNGKESVPILWKFLQKEAELRLVKFLPEVLELQRNLVKRFQNVSEVEYKSIRSFISSHHSDGLKKLALSRITIFLSTWNKLRRSLETNGEIKLPKDYCSSDLDLDTDLEVILPRRKGRGLCSTALVSYLINLHNEIVYAVEKFSKEDNSYSVDASEIADLHVISYEVERDLIPLILSNCQYQVEQGGETLQEFDLEKIQRQIISRFLQGKPRLTLKGLPTLVYRRDWNYEHLFMDIKNKMPQSPLPNAAITAIRGQLQSYSDACEALSATEVTLGFLSAAGGDPDMHLNVYIQDMLKMGDPTSLVSKAFNRCQLKHIIALWRILSAHKSELMLRQEKEPFGEIDSRYKADLNPENAKLLNTFLNHIGLEAFLLDLHDMMILKLKNPKATENFNPEWSLRDTLVSYMETTDSEIPPEMESQFPEEILLSNCVAVWKMAAELKRNRQMR", "length": 758, "header": "tr|A0ABI0NQ81-1|A0ABI0NQ81_BOVIN Isoform 1 of RZ-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NQ81-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NQ81-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ81/entry#A0ABI0NQ81-1", "sequence": { "sequence": "MYQVSISKLAEFKISGNMLGSSSPRHYLVRPESRELGLPFNGGSLGKASPANIVSCSFNSMSNGHVCSVGECGKPMEQSFCIDCRAPIGGINHKPEERFRVIDDTTDRTQTGHVLGNPPPRGAPVVSDRQMSPVVFLLIRLLTHLAMLLGATQSPQDLMNIIKPPVSDPKRFLQQHIQRDLEQLMNTLGRSADETASVVHLVLCRLLQEQSHSSSDFDAELSTREERNRWEKLVETIILHELEYLDKTLLAVNAQISQDERISSNPVAKIVYGDPATFLPHLPKNSMVHCSKMWSCRKRITIEYLQHIVEQKNGKESVPILWKFLQKEAELRLVKFLPEVLELQRNLVKRFQNVSEVEYKSIRSFISSHHSDGLKKLALSRITIFLSTWNKLRRSLETNGEIKLPKDYCSSDLDLDTDLEVILPRRKGRGLCSTALVSYLINLHNEIVYAVEKFSKEDNSYSVDASEIADLHVISYEVERDLIPLILSNCQYQVEQGGETLQEFDLEKIQRQIISRFLQGKPRLTLKGLPTLVYRRDWNYEHLFMDIKNKMPQSPLPNAAITAIRGQLQSYSDACEALSATEVTLGFLSAAGGDPDMHLNVYIQDMLKMGDPTSLVSKAFNRCQLKHIIALWRILSAHKSELMLRQEKEPFGEIDSRYKADLNPENAKLLNTFLNHIGLEAFLLDLHDMMILKLKNPKATENFNPEWSLRDTLVSYMETTDSEIPPEMESQFPEEILLSNCVAVWKMAAELKRNRQMR", "length": 758, "header": "tr|A0ABI0NQ81-1|A0ABI0NQ81_BOVIN Isoform 1 of RZ-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NQ81-1" }, "locus": { "chromosome": "19", "start_pos": 52279790, "end_pos": 52262095, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150317.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150317.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104372.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104372.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ81" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ81" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ81" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ81", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NQ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ81" }, { "id": "PS51981", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51981" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RZ-type", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 111, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 353, "end_pos": 355 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQ98-1", "uniprot_ac": "A0ABI0NQ98", "uniprot_id": "A0ABI0NQ98_BOVIN", "mass": { "chemical_mass": 35469.0, "monoisotopic_mass": 35469.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Phytanoyl-CoA dioxygenase, peroxisomal", "type": "recommended", "evidence": [ { "id": "A0ABI0NQ98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ98/entry#names_and_taxonomy" } ] }, { "name": "1.14.11.18", "type": "synonym", "evidence": [ { "id": "A0ABI0NQ98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ98/entry#names_and_taxonomy" } ] }, { "name": "Phytanic acid oxidase", "type": "synonym", "evidence": [ { "id": "A0ABI0NQ98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ98/entry#names_and_taxonomy" } ] }, { "name": "Phytanoyl-CoA alpha-hydroxylase", "type": "synonym", "evidence": [ { "id": "A0ABI0NQ98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ98/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ98", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ98" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ98", "locus": {} } ], "crossref": [ { "id": "IPR008775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21308:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21308:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05721", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05721", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "16065", "url": "https://www.rhea-db.org/rhea/16065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44000", "url": "https://www.rhea-db.org/rhea/44000", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54596", "url": "https://www.rhea-db.org/rhea/54596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54600", "url": "https://www.rhea-db.org/rhea/54600", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54604", "url": "https://www.rhea-db.org/rhea/54604", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54612", "url": "https://www.rhea-db.org/rhea/54612", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54616", "url": "https://www.rhea-db.org/rhea/54616", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54620", "url": "https://www.rhea-db.org/rhea/54620", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54624", "url": "https://www.rhea-db.org/rhea/54624", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54628", "url": "https://www.rhea-db.org/rhea/54628", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54632", "url": "https://www.rhea-db.org/rhea/54632", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "55172", "url": "https://www.rhea-db.org/rhea/55172", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "55176", "url": "https://www.rhea-db.org/rhea/55176", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "55180", "url": "https://www.rhea-db.org/rhea/55180", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "55184", "url": "https://www.rhea-db.org/rhea/55184", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "55192", "url": "https://www.rhea-db.org/rhea/55192", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NQ98", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ98-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQNHTSSRLRILLRHLDGCLARPTISHPASRPGSPATFHPQQFQYTWENNVLSLEQRKFYEENGFLVIKNLVSDADIQRFRNEFQRICRKEVKPLGLLVMRDVTIAKSEYVPSEKVVSKVQDFQEDEELFRYCTLPEILKYVECFTGPNIMAIHTMLINKPPDFGKKTSRHPLHQDLHYFPFRPSNSIVCAWTAMEHIDRNNGCLAVLPGTHKGPLQPHDYPQWEGGVNIMFHRIQDYDKNNARVHLVMEKGDTVFFHPLLIHGSGRNKSQGFRKVHIHITALFEDECMRKKNLMICWAHISQG", "length": 305, "header": "tr|A0ABI0NQ98-1|A0ABI0NQ98_BOVIN Isoform 1 of Phytanoyl-CoA dioxygenase, peroxisomal OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NQ98-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NQ98-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ98/entry#A0ABI0NQ98-1", "sequence": { "sequence": "MDQNHTSSRLRILLRHLDGCLARPTISHPASRPGSPATFHPQQFQYTWENNVLSLEQRKFYEENGFLVIKNLVSDADIQRFRNEFQRICRKEVKPLGLLVMRDVTIAKSEYVPSEKVVSKVQDFQEDEELFRYCTLPEILKYVECFTGPNIMAIHTMLINKPPDFGKKTSRHPLHQDLHYFPFRPSNSIVCAWTAMEHIDRNNGCLAVLPGTHKGPLQPHDYPQWEGGVNIMFHRIQDYDKNNARVHLVMEKGDTVFFHPLLIHGSGRNKSQGFRKVHIHITALFEDECMRKKNLMICWAHISQG", "length": 305, "header": "tr|A0ABI0NQ98-1|A0ABI0NQ98_BOVIN Isoform 1 of Phytanoyl-CoA dioxygenase, peroxisomal OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NQ98-1" }, "locus": { "chromosome": "13", "start_pos": 27947625, "end_pos": 27934001, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153223.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153223.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104331.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104331.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fatty acid alpha-oxidation", "id": "GO:0001561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001561", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ98", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ98" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phytanoyl-CoA dioxygenase activity", "id": "GO:0048244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048244", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQ98", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ98" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16065", "name": "", "equation": "phytanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyphytanoyl-CoA + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18778-1", "A0ABI0NQ98-1" ], "evidence": [ { "id": "16065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16065" } ] }, { "id": "44000", "name": "", "equation": "3-methylhexadecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxy-3-methylhexadecanoyl-CoA + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18778-1", "A0ABI0NQ98-1" ], "evidence": [ { "id": "44000", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44000" } ] }, { "id": "54596", "name": "", "equation": "hexadecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyhexadecanoyl-CoA + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18778-1", "A0ABI0NQ98-1" ], "evidence": [ { "id": "54596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54596" } ] }, { "id": "54600", "name": "", "equation": "octanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyoctanoyl-CoA + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18778-1", "A0ABI0NQ98-1" ], "evidence": [ { "id": "54600", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54600" } ] }, { "id": "54604", "name": "", "equation": "decanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxydecanoyl-CoA + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18778-1", "A0ABI0NQ98-1" ], "evidence": [ { "id": "54604", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54604" } ] }, { "id": "54612", "name": "", "equation": "3-methylbutanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxy-3-methylbutanoyl-CoA + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18778-1", "A0ABI0NQ98-1" ], "evidence": [ { "id": "54612", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54612" } ] }, { "id": "54616", "name": "", "equation": "heptadecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyheptadecanoyl-CoA + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18778-1", "A0ABI0NQ98-1" ], "evidence": [ { "id": "54616", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54616" } ] }, { "id": "54620", "name": "", "equation": "eicosanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyeicosanoyl-CoA + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18778-1", "A0ABI0NQ98-1" ], "evidence": [ { "id": "54620", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54620" } ] }, { "id": "54624", "name": "", "equation": "octadecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyoctadecanoyl-CoA + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18778-1", "A0ABI0NQ98-1" ], "evidence": [ { "id": "54624", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54624" } ] }, { "id": "54628", "name": "", "equation": "dodecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxydodecanoyl-CoA + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18778-1", "A0ABI0NQ98-1" ], "evidence": [ { "id": "54628", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54628" } ] }, { "id": "54632", "name": "", "equation": "tetradecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxytetradecanoyl-CoA + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18778-1", "A0ABI0NQ98-1" ], "evidence": [ { "id": "54632", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54632" } ] }, { "id": "55172", "name": "", "equation": "hexanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyhexanoyl-CoA + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18778-1", "A0ABI0NQ98-1" ], "evidence": [ { "id": "55172", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/55172" } ] }, { "id": "55176", "name": "", "equation": "butanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxybutanoyl-CoA + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18778-1", "A0ABI0NQ98-1" ], "evidence": [ { "id": "55176", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/55176" } ] }, { "id": "55180", "name": "", "equation": "3-methylnonanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxy-3-methylnonanoyl-CoA + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18778-1", "A0ABI0NQ98-1" ], "evidence": [ { "id": "55180", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/55180" } ] }, { "id": "55184", "name": "", "equation": "3-methylundecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxy-3-methylundecanoyl-CoA 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Delivery to lysosomes by the cargo receptor NCOA4 for autophagic degradation and release or iron.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQL6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL6#function" }, { "database": "UniProtKB", "id": "ARBA00045578", "url": "https://www.uniprot.org/uniprotkb/ARBA00045578#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQL6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC107132075", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL6", "locus": {} } ], "crossref": [ { "id": "cd01056", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01056", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11431", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11431", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11431:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11431:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NQL6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQL6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQSACSQPGLASPSSCLPPPSSPTPSSTASGTIFWTYPPLLRPASQQFVEKSCSLLTMSTQIQQSSPEMEAAASRLIKLHLEVSSTYVSLSVYFEGSGMAMNGVGHFFRMLAKEKQEGAQLLLKMRKSWGDGALVQSGQTLSPEKWNASVEAMEYAVALEKSLNQALLDLHALGRASADVQLCEFLERRFLEDEMMLLKKMGDHLANLRKITSPQAGLQAGLAEYLFEKLSFQCD", "length": 236, "header": "tr|A0ABI0NQL6-1|A0ABI0NQL6_BOVIN Isoform 1 of Ferritin OS=Bos taurus OX=9913 GN=LOC107132075 PE=3 SV=1 CANONICAL=A0ABI0NQL6-1" }, 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"prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 25, "start_aa": "Thr", "end_pos": 25, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr25", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQL6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL6" } ], "pmid": "" }, { "name": "iron ion transport", "id": "GO:0006826", 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"reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NQL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL6" }, { "id": "PS50905", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50905" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ferritin-like diiron", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 213, "start_aa": "Gln", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0ABI0NQL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL6#function" }, { "id": "A0ABI0NQL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL6" }, { "id": "PIRSR601519-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601519-1" } ], "binding_site_uniprot": 161, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 161, "end_pos": 161, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 25 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NQL8-1", "uniprot_ac": "A0ABI0NQL8", "uniprot_id": "A0ABI0NQL8_BOVIN", "mass": { "chemical_mass": 28533.0, "monoisotopic_mass": 28533.0 }, "refseq": { "ac": "NP_001193216", "name": "protein unc-119 homolog B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193216" }, "gene_names": [ { "name": "UNC119B", "type": "recommended", "evidence": [ { "id": "A0ABI0NQL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL8" } ] }, { "name": "UNC119B", "type": "synonym", "evidence": [ { "id": "NP_001193216", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193216" } ] } ], "protein_names": [ { "name": "Protein unc-119 homolog A", "type": "recommended", "evidence": [ { "id": "A0ABI0NQL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL8/entry#names_and_taxonomy" } ] }, { "name": "protein unc-119 homolog B", "type": "synonym", "evidence": [ { "id": "NP_001193216", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193216" } ] }, { "name": "unc-119 homolog B", "type": "synonym", "evidence": [ { "id": "NP_001193216", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193216" } ] } ], "function": [ { "annotation": "Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Probably plays a role in trafficking proteins in photoreceptor cells. Plays important roles in mediating Src family kinase signals for the completion of cytokinesis via RAB11A.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQL8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL8#function" }, { "database": "UniProtKB", "id": "ARBA00045349", "url": "https://www.uniprot.org/uniprotkb/ARBA00045349#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NQL8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UNC119B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL8", "locus": { "chromosome": "17", "start_pos": 62964687, "end_pos": 62955311, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007483", "url": 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"MSGSNSKAAALGSAVGPAGLVTGKEEKKKAGGGVLNRLKGRRQAPHHAADDGIGAAVTEQELLALDTIRPEHVLRLSQVTENYLCKPEDNIYSIDFTRFKIRDLETGTVLFEIAKPCVSDQEEEEDEEGEAGGDVDVSAGRFVRYQFTPAFLRLRTVGATVEFTVGDKPVSNFRMIERHYFRERLLKNFDFDFGFCIPSSRNTCEHIYEFPQLSEDVIRLMIENPYETRSDSFYFVDNKLIMHNKADYAYNGGQ", "length": 254, "header": "tr|A0ABI0NQL8-1|A0ABI0NQL8_BOVIN Isoform 1 of Protein unc-119 homolog A OS=Bos taurus OX=9913 GN=UNC119B PE=3 SV=1 CANONICAL=A0ABI0NQL8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NQL8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQL8/entry#A0ABI0NQL8-1", "sequence": { "sequence": "MSGSNSKAAALGSAVGPAGLVTGKEEKKKAGGGVLNRLKGRRQAPHHAADDGIGAAVTEQELLALDTIRPEHVLRLSQVTENYLCKPEDNIYSIDFTRFKIRDLETGTVLFEIAKPCVSDQEEEEDEEGEAGGDVDVSAGRFVRYQFTPAFLRLRTVGATVEFTVGDKPVSNFRMIERHYFRERLLKNFDFDFGFCIPSSRNTCEHIYEFPQLSEDVIRLMIENPYETRSDSFYFVDNKLIMHNKADYAYNGGQ", "length": 254, "header": "tr|A0ABI0NQL8-1|A0ABI0NQL8_BOVIN Isoform 1 of Protein unc-119 homolog A OS=Bos taurus OX=9913 GN=UNC119B PE=3 SV=1 CANONICAL=A0ABI0NQL8-1" }, 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"https://www.ebi.ac.uk/interpro/entry/IPR051061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46179", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46179", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46179:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46179:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059739782", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739782", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NR58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NR58-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR58-1", "database": "UniProtKB", 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GN=LOC510362 PE=4 SV=1 CANONICAL=A0ABI0NR58-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NR58-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR58/entry#A0ABI0NR58-1", "sequence": { "sequence": "MEIPRLLPARGMRQTGGAGSPEGSGRIRGGPDLRASQAPARRLLLLRGPQDGGPGRRREEASAASSCPGPGPGPSPLALRPDHASSCGSGGGSGGDDFFLVLLDPVGGDVDTAGAGQATGPVWREEAGLGPRLLGGESGANPEGRPALGPSCLSAIPAPVPALAPIPASGLGPAAAFAGTVAIHNQNLLLRLENGVLTLATPPPQPGGLIVPQAGIPHAAQPGDCPELPPDLLLAERAEPAPAPAPKEEAEGLAAIESPRGPPGPGQGVLLYLCPEVQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLGGCGWTFTTSYKLKRHLQSHDKLRPFGCPAEGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEETFPTQAKLSAHQRSHFEPERPYQCAFSSCKKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFEGCGWNFTSMSKLLRHKRKHDDDRRFMCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVEGCCARFSARSSLYIHSKKHLQDVDTWKSRCPVATCNKLFTSKHSMKTHMAKRHNLRQDLLAQLEAANSLTPSSELTSQGQSDLSDAELVSLFSDVPGNNSSAAVLDTALVNSGILTIDVASVNSTLAGNLPANNNNSLGQAVDPQALMATSDLPQSLDTSLFFGTTAAGFQQGPLDMDDVSSLSAGPLASLSSLALKNSSQEPQALIPSSKLTVDTDALTPSSTLCENSVSELLPPTKTEWNVHPDSDFFAQEEETQFGFSNPAGNHGSQKETDLITVTGSSFLV", "length": 805, "header": "tr|A0ABI0NR58-1|A0ABI0NR58_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=LOC510362 PE=4 SV=1 CANONICAL=A0ABI0NR58-1" }, "locus": { "chromosome": "X", "start_pos": 97043896, "end_pos": 97041482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149358.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149358.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105003.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105003.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NR58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR58" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 618, "end_pos": 620, "annotation": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NR71-1", "uniprot_ac": "A0ABI0NR71", "uniprot_id": "A0ABI0NR71_BOVIN", "mass": { "chemical_mass": 57904.0, "monoisotopic_mass": 57904.0 }, "refseq": { "ac": "XP_059740107", "name": "melanoma antigen preferentially expressed in tumors-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740107" }, "gene_names": [ { "name": "LOC132344500", "type": "recommended", "evidence": [ { "id": "A0ABI0NR71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR71" } ] }, { "name": "LOC132344485", "type": "synonym", "evidence": [ { "id": "A0ABI0NR71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR71" } ] }, { "name": "LOC132344486", "type": "synonym", "evidence": [ { "id": "A0ABI0NR71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR71" } ] }, { "name": "LOC132344499", "type": "synonym", "evidence": [ { "id": "A0ABI0NR71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR71" } ] }, { "name": "LOC132344500", "type": "synonym", "evidence": [ { "id": "XP_059740107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740107" } ] } ], "protein_names": [ { "name": "Preferentially expressed antigen in melanoma", "type": "recommended", "evidence": [ { "id": "A0ABI0NR71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR71/entry#names_and_taxonomy" } ] }, { "name": "melanoma antigen preferentially expressed in tumors-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059740107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740107" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NR71", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR71" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC132344500", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NR71", "locus": {} } ], "crossref": [ { "id": "132344500", "url": "https://www.ncbi.nlm.nih.gov/gene/132344500", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14224:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14224:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059740107", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NRA4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRA4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6E4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6E4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGARPGPQLLALLRPQSPMAAAALKVPPEGQVTFEDVAVYFSWEEWGLLDEAQRLLYCGVMLETFSLMASLGLTPSRTHAMTQLEQRGEPCVPTGGVSTTATPAGCWCGAEADEAPSEQSGCVEADRANLHQHQDPNSGEKPSTREEHEGNGKVSPGSSGLPKPQAAPSGGEPCRSTKSGEGVPPGKRHYRCSECGKAFGQKYLLVQHQRLHTGEKPYECSECGKLFSHKSNLFIHQIVHTGERPYGCSECGKSFSRNADLIQHRRVHTGEKPFKCSECGKAFRHNSTLVQHHRIHTGVRPYECSECGKFFSFNSSLMKHQRVHTGERPYKCSECGKFYSHKSSLINHWRVHTGERPYECSECGKFFSQSSSLVQHRKVHTGEKPFKCNECGRFFSENSSLVKHQRVHTGARPYGCRECGKFFRHSSSLVKHRRIHTGEMPYECSSCGKSFSQRFNLIQHQKVHSGEKSCKVQL", "length": 475, "header": "tr|A0ABI0NRA4-1|A0ABI0NRA4_BOVIN Isoform 1 of Zinc finger protein 419 OS=Bos taurus OX=9913 GN=ZNF419 PE=3 SV=1 CANONICAL=A0ABI0NRA4-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NRA4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRA4/entry#A0ABI0NRA4-1", "sequence": { "sequence": "MRGARPGPQLLALLRPQSPMAAAALKVPPEGQVTFEDVAVYFSWEEWGLLDEAQRLLYCGVMLETFSLMASLGLTPSRTHAMTQLEQRGEPCVPTGGVSTTATPAGCWCGAEADEAPSEQSGCVEADRANLHQHQDPNSGEKPSTREEHEGNGKVSPGSSGLPKPQAAPSGGEPCRSTKSGEGVPPGKRHYRCSECGKAFGQKYLLVQHQRLHTGEKPYECSECGKLFSHKSNLFIHQIVHTGERPYGCSECGKSFSRNADLIQHRRVHTGEKPFKCSECGKAFRHNSTLVQHHRIHTGVRPYECSECGKFFSFNSSLMKHQRVHTGERPYKCSECGKFYSHKSSLINHWRVHTGERPYECSECGKFFSQSSSLVQHRKVHTGEKPFKCNECGRFFSENSSLVKHQRVHTGARPYGCRECGKFFRHSSSLVKHRRIHTGEMPYECSSCGKSFSQRFNLIQHQKVHSGEKSCKVQL", "length": 475, "header": "tr|A0ABI0NRA4-1|A0ABI0NRA4_BOVIN Isoform 1 of Zinc finger protein 419 OS=Bos taurus OX=9913 GN=ZNF419 PE=3 SV=1 CANONICAL=A0ABI0NRA4-1" }, "locus": { "chromosome": "18", "start_pos": 64704926, "end_pos": 64698264, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144439.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144439.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104990.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104990.1" } ] } }, { "isoform_ac": "A0ABI0P6E4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRA4/entry#A0ABI0P6E4-1", "sequence": { "sequence": "MIKVLLIVPCSGPWVQVAVAAEWLPDHEEGQVTFEDVAVYFSWEEWGLLDEAQRLLYCGVMLETFSLMASLGLTPSRTHAMTQLEQRGEPCVPTGGVSTTATPAGCWCGAEADEAPSEQSGCVEADRANLHQHQDPNSGEKPSTREEHEGNGKVSPGSSGLPKPQAAPSGGEPCRSTKSGEGVPPGKRHYRCSECGKAFGQKYLLVQHQRLHTGEKPYECSECGKLFSHKSNLFIHQIVHTGERPYGCSECGKSFSRNADLIQHRRVHTGEKPFKCSECGKAFRHNSTLVQHHRIHTGVRPYECSECGKFFSFNSSLMKHQRVHTGERPYKCSECGKFYSHKSSLINHWRVHTGERPYECSECGKFFSQSSSLVQHRKVHTGEKPFKCNECGRFFSENSSLVKHQRVHTGARPYGCRECGKFFRHSSSLVKHRRIHTGEMPYECSSCGKSFSQRFNLIQHQKVHSGEKSCKVQL", "length": 474, "header": "tr|A0ABI0P6E4-1|A0ABI0P6E4_BOVIN Computationally mapped isoform of Zinc finger protein 419 OS=Bos taurus OX=9913 GN=ZNF419 PE=3 SV=1 CANONICAL=A0ABI0NRA4-1" }, "locus": { "chromosome": "18", "start_pos": 64704926, "end_pos": 64698398, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152193.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152193.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107502.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107502.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": 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"n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NRA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRA4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 191, "end_pos": 218, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NRA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRA4" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 104, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 103 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 287, "end_pos": 289 }, { "start_pos": 315, "end_pos": 317 }, { "start_pos": 399, "end_pos": 401 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NRA5-1", "uniprot_ac": "A0ABI0NRA5", "uniprot_id": "A0ABI0NRA5_BOVIN", "mass": { "chemical_mass": 12356.0, "monoisotopic_mass": 12356.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Immunoglobulin V-set domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NRA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRA5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRA5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRA5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], 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"categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NRA5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRA5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "TSLVEQKPRWVLVPRRQAETLRCILKDSQYPWMSWYQQDLRGQLQVLASLRRTGDKEVINLPGANYRATRVSESELSLHVANVTQGRTLFCTCSKDTVRHPNWENE", "length": 106, "header": "tr|A0ABI0NRA5-1|A0ABI0NRA5_BOVIN Isoform 1 of Immunoglobulin V-set domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NRA5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NRA5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRA5/entry#A0ABI0NRA5-1", "sequence": { "sequence": 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[ { "database": "UniProtKB", "id": "A0ABI0NRA5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRA5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRA5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NRA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRA5" }, { "id": "PF07686", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686" } ], "ann_type": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376842" }, "gene_names": [ { "name": "OR4D1B", "type": "recommended", "evidence": [ { "id": "A0ABI0NRB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRB6" } ] }, { "name": "OR4D1B", "type": "synonym", "evidence": [ { "id": "NP_001376842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376842" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NRB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRB6/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 4 subfamily D member 1B", "type": "synonym", "evidence": [ { "id": "NP_001376842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376842" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376842", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376842" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRB6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRB6#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRB6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRB6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4D1B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRB6", "locus": {} } ], "crossref": [ { "id": "cd15936", "url": 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"MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRSTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLFPFCLQIFKTEALYICHYRQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPKTKVVIQVSLEPLQPGLVEVASITVNASDYEPSPPKSKSRRSKKPG", "length": 543, "header": "tr|A0ABI0NRQ0-1|A0ABI0NRQ0_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NRQ0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NRQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ0/entry#A0ABI0NRQ0-1", "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRSTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLFPFCLQIFKTEALYICHYRQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPKTKVVIQVSLEPLQPGLVEVASITVNASDYEPSPPKSKSRRSKKPG", "length": 543, "header": "tr|A0ABI0NRQ0-1|A0ABI0NRQ0_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NRQ0-1" }, "locus": { "chromosome": "Y", "start_pos": 54477282, "end_pos": 54475654, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139531.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139531.1" }, { "database": "Ensembl Peptide", "id": 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"https://www.uniprot.org/uniprotkb/A0ABI0NRQ0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 343, "end_pos": 371, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 68, 96 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 523, "end_pos": 525 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": 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"type": "synonym", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5/entry#names_and_taxonomy" } ] }, { "name": "ERK activator kinase 1", "type": "synonym", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5/entry#names_and_taxonomy" } ] }, { "name": "MAPK/ERK kinase 1", "type": "synonym", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRQ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC101905399", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5", "locus": {} } ], "crossref": [ { "id": "cd06650", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06650", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47448", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47448", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47448:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47448:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NRQ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTNLDSLFKSRDITLPTKVRLVKAMIGKKMRTNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSWDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDTAETPPRPRTPGRPLSFYGMDSRPPMAVFEFLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV", "length": 379, "header": "tr|A0ABI0NRQ5-1|A0ABI0NRQ5_BOVIN Isoform 1 of Dual specificity mitogen-activated protein kinase kinase 1 OS=Bos taurus OX=9913 GN=LOC101905399 PE=3 SV=1 CANONICAL=A0ABI0NRQ5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NRQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5/entry#A0ABI0NRQ5-1", "sequence": { "sequence": "MTNLDSLFKSRDITLPTKVRLVKAMIGKKMRTNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSWDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDTAETPPRPRTPGRPLSFYGMDSRPPMAVFEFLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV", "length": 379, "header": "tr|A0ABI0NRQ5-1|A0ABI0NRQ5_BOVIN Isoform 1 of Dual specificity mitogen-activated protein kinase kinase 1 OS=Bos taurus OX=9913 GN=LOC101905399 PE=3 SV=1 CANONICAL=A0ABI0NRQ5-1" }, "locus": { "chromosome": "5", "start_pos": 39418833, "end_pos": 39416847, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143519.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143519.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106422.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106422.1" } ] } } ], "glycosylation": [], "phosphorylation": [], 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"name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRQ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRQ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRQ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ], "pmid": "" }, { "name": "MAP kinase kinase activity", "id": "GO:0004708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004708", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRQ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRQ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRQ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRQ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRQ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRQ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NRQ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MWN2-1", "A0AAF6DMB3-1", "E1BI01-1", "A0AAA9TQL1-1", "F1MQH2-1", "F1N781-1", "F6QXU6-1", "A0A3Q1MKW9-1", 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{ "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SA57", "gene_name": "ABL2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SA57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA57" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SA57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA57" } ] } ] }, { "uniprot_ac": "A0AAA9SBR4", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SBR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SBR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR4" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SN20", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN20" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN20" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SPC9", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SPC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SPC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC9" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVL9", "gene_name": "FLT4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SW95", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SXH6", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TAT1", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9THG2", "gene_name": "EPHB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG2" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TMY2", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMY2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9TMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMY2" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TQL1", "gene_name": "DDR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] } ] }, { "uniprot_ac": "A0AAA9TRY4", "gene_name": "CSF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMB3", "gene_name": "DDR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P1V8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A0JNB0", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B6X6", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B6X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1B6X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X6" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9H4", "gene_name": "PKDCC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BCZ6", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEL4", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] } ] }, { "uniprot_ac": "E1BER5", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER5" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BIM8", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJ31", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BJS9", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKP7", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BMP9", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNA8", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] } ] }, { "uniprot_ac": "E1BNE0", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPI3", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC14", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] } ] }, { "uniprot_ac": "F1MC23", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MCX4", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFH7", "gene_name": "EPHA1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MII5", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKR1", "gene_name": "EPHA8", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1ML02", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MN51", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MNW2", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MQH2", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] } ] }, { "uniprot_ac": "F1MRU0", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] } ] }, { "uniprot_ac": "F1MS00", "gene_name": "RET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] } ] }, { "uniprot_ac": "F1MS29", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWN2", "gene_name": "HCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MX49", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N0D3", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] } ] }, { "uniprot_ac": "F1N1Q0", "gene_name": "SRMS", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] } ] }, { "uniprot_ac": "F1N261", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N381", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] } ] }, { "uniprot_ac": "F1N3R6", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F1N6H6", "gene_name": "EPHA10", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6H6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6H6" } ] } ] }, { "uniprot_ac": "F1N6J0", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6J0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N6J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6J0" } ] } ] }, { "uniprot_ac": "F1N758", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] } ] }, { "uniprot_ac": "F1N759", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] } ] }, { "uniprot_ac": "F1N780", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N780" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N780" } ] } ] }, { "uniprot_ac": "F1N781", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N781" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N781" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QXU6", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QXU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6QXU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "F6S1J8", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ] } ] }, { "uniprot_ac": "G1K218", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G1K218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "G1K218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G3X680", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3X680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X680" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "G3X680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X680" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P43481", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q05688", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05688" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q05688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05688" } ] } ] }, { "uniprot_ac": "Q06805", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q06805", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06805" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q06805", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06805" } ] } ] }, { "uniprot_ac": "Q06807", "gene_name": "TEK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q06807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06807" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q06807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q06807" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VBZ0", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "Q0VBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VBZ0" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] } ] }, { "uniprot_ac": "Q5E9Y9", "gene_name": "NME7", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": 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{ "annotation": "Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NTP3-1", "uniprot_ac": "A0ABI0NTP3", "uniprot_id": "A0ABI0NTP3_BOVIN", "mass": { "chemical_mass": 49451.0, "monoisotopic_mass": 49451.0 }, "refseq": { "ac": "NP_001104002", "name": "BAG family molecular chaperone regulator 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104002" }, "gene_names": [ { "name": "BAG4", "type": "recommended", "evidence": [ { "id": "A0ABI0NTP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP3" } ] }, { "name": "BAG4", "type": "synonym", "evidence": [ { "id": "NP_001104002", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104002" } ] } ], "protein_names": [ { "name": "BAG family molecular chaperone regulator 4", "type": "recommended", "evidence": [ { "id": "A0ABI0NTP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP3/entry#names_and_taxonomy" } ] }, { "name": "BAG family molecular chaperone regulator 4", "type": "synonym", "evidence": [ { "id": "NP_001104002", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104002" } ] }, { "name": "BCL2 associated athanogene 4", "type": "synonym", "evidence": [ { "id": "NP_001104002", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104002" } ] }, { "name": "Bcl-2-associated athanogene 4", "type": "synonym", "evidence": [ { "id": "A0ABI0NTP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP3/entry#names_and_taxonomy" } ] }, { "name": "Silencer of death domains", "type": "synonym", "evidence": [ { "id": "A0ABI0NTP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Prevents constitutive TNFRSF1A signaling. Negative regulator of PRKN translocation to damaged mitochondria.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS25", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS25#function" }, { "database": "UniProtKB", "id": "ARBA00059955", "url": "https://www.uniprot.org/uniprotkb/ARBA00059955#function" }, { "database": "UniProtKB", "id": "A0ABI0NTP3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTP3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BAG4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP3", "locus": { "chromosome": "27", "start_pos": 33374595, "end_pos": 33349063, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013143", "url": "https://www.ensembl.org/id/ENSBTAG00000013143" } ] } } ], "crossref": [ { "id": "516353", "url": "https://www.ncbi.nlm.nih.gov/gene/516353", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:516353", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516353", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR12329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12329:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12329:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001104002", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104002", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NS25", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS25-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTP3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTP3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSALRRSGYGPSDGPSYGRYYGPGGGDVPVHPPPPIYPPRPEPPQPPISWRGRGGGPAETTWPGEGGGGDGYYASGGAWSEPGRAGGGHQEQPPYPSYNSNYWNSAARPRAPYPSTYPVRPEMQSQSLNSYTNGGYGPPYPTGPGTNTASYPGAYYTPGYAQTNYSTEVPSTYRSPGNSPTPVSRWMYPQQDCQTEAPPLRGQVPGYPASQNPGMSVPHYPYGDGNRSVPQPGPPVRPQEDSWAPPGAYGMGTRYPWPSAAPSGPPGSLYMNESTSSWPSSGSPQSPPSPPPPQPKDSSYTYSQPDQGMSQHNFPCNVHQYESSGSVNDDSSELLDPQVQYSAEPHLYGNASHEHPSTQDQGNHLAEECLSSDEGTPPSIKKIIHVLEKVQYLEQEVEEFVGKKTDKAYWLLEEMLTKELLELDSVETGGQDSVRQARKEAVCKIQAILEKLEKKGL", "length": 457, "header": "tr|A0ABI0NTP3-1|A0ABI0NTP3_BOVIN Isoform 1 of BAG family molecular chaperone regulator 4 OS=Bos taurus OX=9913 GN=BAG4 PE=4 SV=1 CANONICAL=A0ABI0NTP3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NS25-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP3/entry#A0ABI0NS25-1", "sequence": { "sequence": "MSALRRSGYGPSDGPSYGRYYGPGGGDVPVHPPPPIYPPRPEPPQPPISWRGRGGGPAETTWPGEGGGGDGYYASGGAWSEPGRAGGGHQSLNSYTNGGYGPPYPTGPGTNTASYPGAYYTPGYAQTNYSTEVPSTYRSPGNSPTPVSRWMYPQQDCQTEAPPLRGQVPGYPASQNPGMSVPHYPYGDGNRSVPQPGPPVRPQEDSWAPPGAYGMGTRYPWPSAAPSGPPGSLYMNESTSSWPSSGSPQSPPSPPPPQPKDSSYTYSQPDQGMSQHNFPCNVHQYESSGSVNDDSSELLDPQVQYSAEPHLYGNASHEHPSTQDQGNHLAEECLSSDEGTPPSIKKIIHVLEKVQYLEQEVEEFVGKKTDKAYWLLEEMLTKELLELDSVETGGQDSVRQARKEAVCKIQAILEKLEKKGL", "length": 421, "header": "tr|A0ABI0NS25-1|A0ABI0NTP3_BOVIN Computationally mapped isoform of BAG family molecular chaperone regulator 4 OS=Bos taurus OX=9913 GN=BAG4 PE=4 SV=1 CANONICAL=A0ABI0NTP3-1" }, "locus": { "chromosome": "27", "start_pos": 33373347, "end_pos": 33349113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152700.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152700.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106703.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106703.1" } ] } }, { "isoform_ac": "A0ABI0NTP3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP3/entry#A0ABI0NTP3-1", "sequence": { "sequence": "MSALRRSGYGPSDGPSYGRYYGPGGGDVPVHPPPPIYPPRPEPPQPPISWRGRGGGPAETTWPGEGGGGDGYYASGGAWSEPGRAGGGHQEQPPYPSYNSNYWNSAARPRAPYPSTYPVRPEMQSQSLNSYTNGGYGPPYPTGPGTNTASYPGAYYTPGYAQTNYSTEVPSTYRSPGNSPTPVSRWMYPQQDCQTEAPPLRGQVPGYPASQNPGMSVPHYPYGDGNRSVPQPGPPVRPQEDSWAPPGAYGMGTRYPWPSAAPSGPPGSLYMNESTSSWPSSGSPQSPPSPPPPQPKDSSYTYSQPDQGMSQHNFPCNVHQYESSGSVNDDSSELLDPQVQYSAEPHLYGNASHEHPSTQDQGNHLAEECLSSDEGTPPSIKKIIHVLEKVQYLEQEVEEFVGKKTDKAYWLLEEMLTKELLELDSVETGGQDSVRQARKEAVCKIQAILEKLEKKGL", "length": 457, "header": "tr|A0ABI0NTP3-1|A0ABI0NTP3_BOVIN Isoform 1 of BAG family molecular chaperone regulator 4 OS=Bos taurus OX=9913 GN=BAG4 PE=4 SV=1 CANONICAL=A0ABI0NTP3-1" }, "locus": { "chromosome": "27", "start_pos": 33373347, "end_pos": 33349113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143618.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143618.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106926.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106926.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:516353", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516353", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTP3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NTP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTP3" }, { "id": "PS51035", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAG", "eco_id": "ECO_0000259", "start_pos": 379, "end_pos": 456, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 350, "end_pos": 352 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NS34-1", "uniprot_ac": "A0ABI0NS34", "uniprot_id": "A0ABI0NS34_BOVIN", "mass": { "chemical_mass": 29805.0, "monoisotopic_mass": 29805.0 }, "refseq": {}, "gene_names": [ { "name": "RSRP1", "type": "recommended", "evidence": [ { "id": "A0ABI0NS34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS34" } ] } ], "protein_names": [ { "name": "Arginine/serine-rich protein 1", "type": "recommended", "evidence": [ { "id": "A0ABI0NS34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS34/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Probably acts as a spliceosomal factor that contributes to spliceosome assembly and regulates the isoform switching of proteins such as PARP6.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS34", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS34#function" }, { "database": "UniProtKB", "id": "ARBA00034666", "url": "https://www.uniprot.org/uniprotkb/ARBA00034666#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS34", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS34" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RSRP1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS34", "locus": {} } ], "crossref": [ { "id": "IPR029656", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029656", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47622", "url": 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"MSSYVNDLWSGSPPKASPSSSRSGSCSQPSSASGSRSPSRSSVSSRSWSRSRSPPGRRSRSRSRSRRRHQRRYRRYSRSYSRSHSRSRSRRYRERHSGSTRRSYRSRSRSRGRLYYRSAYAIARGRHYYGFGRTVYPEERRSWRGRSRSRSRSPTPFRLSEKDRMELLEIAKANAAKALGTANFDLPASLRSVPVSKERNQETAVLTNGAKSEVSILFILKIISNFISKLKLNIKIKKLFRRLLPERADYPFLFHLP", "length": 257, "header": "tr|A0ABI0NS34-1|A0ABI0NS34_BOVIN Isoform 1 of Arginine/serine-rich protein 1 OS=Bos taurus OX=9913 GN=RSRP1 PE=3 SV=1 CANONICAL=A0ABI0NS34-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NS34-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS34/entry#A0ABI0NS34-1", "sequence": { "sequence": "MSSYVNDLWSGSPPKASPSSSRSGSCSQPSSASGSRSPSRSSVSSRSWSRSRSPPGRRSRSRSRSRRRHQRRYRRYSRSYSRSHSRSRSRRYRERHSGSTRRSYRSRSRSRGRLYYRSAYAIARGRHYYGFGRTVYPEERRSWRGRSRSRSRSPTPFRLSEKDRMELLEIAKANAAKALGTANFDLPASLRSVPVSKERNQETAVLTNGAKSEVSILFILKIISNFISKLKLNIKIKKLFRRLLPERADYPFLFHLP", "length": 257, "header": "tr|A0ABI0NS34-1|A0ABI0NS34_BOVIN Isoform 1 of Arginine/serine-rich protein 1 OS=Bos taurus OX=9913 GN=RSRP1 PE=3 SV=1 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"url": "https://www.ebi.ac.uk/interpro/entry/IPR051115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12479", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12479", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12479:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12479:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03821", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03821", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NSB2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSB2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSMAMKMVAPWTRFSSNSCCLCCHVRTGTILLGVWYLILNAVVLLILLSALDDPDHYHFSSSELGGDFEFMDDANMCIAIAISVLMILICAMATYGAYKQRAGWIIPFFCYQIFDFALNTLVAVTVLLPPDFPYKDDIMSVNPTCLVLIILLFISIILAFKGYLISCVWNCYRYINGRNSSDVLVYVTSNDTTVLLPPYDDATVNSATKEPPPPYVSA", "length": 219, "header": "tr|A0ABI0NSB2-1|A0ABI0NSB2_BOVIN Isoform 1 of Lysosomal-associated transmembrane protein 4B OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NSB2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NSB2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSB2/entry#A0ABI0NSB2-1", "sequence": { "sequence": "MQSMAMKMVAPWTRFSSNSCCLCCHVRTGTILLGVWYLILNAVVLLILLSALDDPDHYHFSSSELGGDFEFMDDANMCIAIAISVLMILICAMATYGAYKQRAGWIIPFFCYQIFDFALNTLVAVTVLLPPDFPYKDDIMSVNPTCLVLIILLFISIILAFKGYLISCVWNCYRYINGRNSSDVLVYVTSNDTTVLLPPYDDATVNSATKEPPPPYVSA", "length": 219, "header": "tr|A0ABI0NSB2-1|A0ABI0NSB2_BOVIN Isoform 1 of Lysosomal-associated transmembrane protein 4B OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NSB2-1" }, "locus": { "chromosome": "19", "start_pos": 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} ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSB2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSB2" } ], "pmid": "" }, { "name": "multivesicular body membrane", "id": "GO:0032585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032585", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSB2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], 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[provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376672" }, "gene_names": [ { "name": "OR2A62", "type": "recommended", "evidence": [ { "id": "A0ABI0NSC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSC5" } ] }, { "name": "OR2A62", "type": "synonym", "evidence": [ { "id": "NP_001376672", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376672" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 2 subfamily A member 62", "type": "synonym", "evidence": [ { "id": "A0ABI0NSC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSC5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2A1/2A42", "type": "synonym", "evidence": [ { "id": "NP_001376672", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376672" } ] }, { "name": "olfactory receptor family 2 subfamily A member 62", "type": "synonym", "evidence": [ { "id": "NP_001376672", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376672" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376672", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376672" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSC5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSC5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSC5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSC5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2A62", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSC5", "locus": {} } ], "crossref": [ { "id": "504233", "url": 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"gene_names": [], "protein_names": [ { "name": "Cadherin domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NSD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSD9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSD9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSD9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSD9", "locus": {} } ], "crossref": [ { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF139", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF139", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NSD9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSD9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METPLPKMTQKRQVTAIIILLLLWEAGGQIIKYSVLEERDSGSFVANLAKDLGLGLGELVSRGARILFKGNKQHLQIEQKSGNLILKEKLDREDLCGDTDPCILHFQVLLKNPVQFIQGELQIQDVNDHAPEFLENEILLKISESSHPGSAYPLKIAQDLDVGSNTVQNYTISSNFHFHLFTRNHSDGRKYPELVLDQELDREEQPELRLTLTAMDGGSPPKTGTSQVLIIVLDINDNAPEFAQQLYQVQVPENSPIGSLVITVSARDLDAGIHGELSYSFFQSSNQVIQAFEVNTATGDIRLKKKLDFEEIRSYHMEIEASDGGGLSGKCTVAIEVMDVNDNAPELTVSLLINDIPENTPDTVVAVFGISDSDSGNNGKMMCSIQDHLPFLLKLTIENFYTLVTEGALDREEKAEYNITITVTDMGTPRLKTEHNITVLVSDVNDNAPTFTQTSYTLWVRENNSPALHIGSVSATDTDAGANAQVTYSLLPPPDPLVPLASLVSINPDNGHLFALTSLDYEALRAFEFRVGATDRGSPALSSQALVRVLVADANDNAPFVLYPLQNASAPCTELVPRAAEPGYLVTKVVAVDGDAGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAPKQRLVVLVKDNGEPPLSASVTLHVLLVDGFSQPYLPAPEAEAAAAAPADPLTVYLVVALASVSSLFLFSVLVFVAVRLCRRGGAASAGRCPVAEGHFPGHLVDVSGTGTLSQSYQYEVCLMGGTGSGEFKFLKPIVPSLMSEGAGMDTAENANFINRLGFN", "length": 797, "header": "tr|A0ABI0NSD9-1|A0ABI0NSD9_BOVIN Isoform 1 of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NSD9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NSD9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSD9/entry#A0ABI0NSD9-1", "sequence": { "sequence": "METPLPKMTQKRQVTAIIILLLLWEAGGQIIKYSVLEERDSGSFVANLAKDLGLGLGELVSRGARILFKGNKQHLQIEQKSGNLILKEKLDREDLCGDTDPCILHFQVLLKNPVQFIQGELQIQDVNDHAPEFLENEILLKISESSHPGSAYPLKIAQDLDVGSNTVQNYTISSNFHFHLFTRNHSDGRKYPELVLDQELDREEQPELRLTLTAMDGGSPPKTGTSQVLIIVLDINDNAPEFAQQLYQVQVPENSPIGSLVITVSARDLDAGIHGELSYSFFQSSNQVIQAFEVNTATGDIRLKKKLDFEEIRSYHMEIEASDGGGLSGKCTVAIEVMDVNDNAPELTVSLLINDIPENTPDTVVAVFGISDSDSGNNGKMMCSIQDHLPFLLKLTIENFYTLVTEGALDREEKAEYNITITVTDMGTPRLKTEHNITVLVSDVNDNAPTFTQTSYTLWVRENNSPALHIGSVSATDTDAGANAQVTYSLLPPPDPLVPLASLVSINPDNGHLFALTSLDYEALRAFEFRVGATDRGSPALSSQALVRVLVADANDNAPFVLYPLQNASAPCTELVPRAAEPGYLVTKVVAVDGDAGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAPKQRLVVLVKDNGEPPLSASVTLHVLLVDGFSQPYLPAPEAEAAAAAPADPLTVYLVVALASVSSLFLFSVLVFVAVRLCRRGGAASAGRCPVAEGHFPGHLVDVSGTGTLSQSYQYEVCLMGGTGSGEFKFLKPIVPSLMSEGAGMDTAENANFINRLGFN", "length": 797, "header": "tr|A0ABI0NSD9-1|A0ABI0NSD9_BOVIN Isoform 1 of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NSD9-1" }, "locus": { "chromosome": "7", "start_pos": 52266107, "end_pos": 52263717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152362.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152362.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105857.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105857.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSD9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSD9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSD9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSD9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSD9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSD9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF02373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21322", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21322", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "60224", "url": "https://www.rhea-db.org/rhea/60224", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NSF7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSF7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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"MKSCGVSLAAAAPAFSDEEKKMAAGKPRSKTKEGTLSLTAEEREELSGLDSLLFGFLNLHEDGAKTETLLLKAVCCYESLILKAEGKVESEFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFYYNAFHWAIKAFQEVLYVEPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDSNPCTLSSVEIQFHIAHLYETQRMYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNVDLLGDQATKESCAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKSCSNTSMLTGRIKVLQAQLCNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQAYKARHPNTEPILGLNETAISQQPLPVHMITHSQVDDQSSPAKRKRISSPAKYLEQLRTDRDNLNTTQKLMLQQLESQFVLMQQMRQTGQTTGIPNGPIADSSLPTNSLSSQQPHSAVPRVSSVSQPEVHSACFENPLSSGPFPARYILSGTSKPLGCTDTNLVGNNYLTRSGNNGNVPYLQQNTFTLPHNCTNLTSSTEEPWRKQLSNSTQGFNKGQNSHLPGSNDEQPSFSTDPALYLQAASTNIQTSHRMLPTSSVTQGTAFNHLSHIATSGDQQGICYTKESTPSGNRSSVPEISSHTEDKPNGCAGVKGLSNRVQQLMAEPICSPNSGDSTSPNFISDNPQISSLLIGKANDTMITGACDKVNSIHPESHTTTNNSVASLHSSIISTTALKSVDHTTTFGVTSISSSHIRLQTVNGKGLENSHSSKNTSLPMISRKPDSPIIPSMSVSIYSNSTEVLKACRNLDKNGLSNSHNLLDKCPPPKPPTSPYPPLPKDKLNPPTPSIYLESKRDAFFPPLHQFCINPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHTVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRMQHREYSDNESTSSDNTGRRRKGPFKTIKFGTNIDLSDDKKWKLQLLELTKLPAFVRVVSAGNLLSHLGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTASQYKLAVERYEWNKLQSVKSVVPMVHLSWNMARNIKVSDPKLFEMIKYCLMKILKQCLTLREALITAGKEVIWHGRTNDEPAHYCSICEVEVFDLLFVTNESNFQKTYIVHCQDCARKASGNLDNFVVLEEYKMEDLIQVYDQFTLAPSVSSSSS", "length": 1406, "header": "tr|A0ABI0NSF7-1|A0ABI0NSF7_BOVIN Isoform 1 of [histone H3]-trimethyl-L-lysine(27) demethylase OS=Bos taurus OX=9913 GN=LOC132344466 PE=3 SV=1 CANONICAL=A0ABI0NSF7-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NSF7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF7/entry#A0ABI0NSF7-1", "sequence": { "sequence": "MKSCGVSLAAAAPAFSDEEKKMAAGKPRSKTKEGTLSLTAEEREELSGLDSLLFGFLNLHEDGAKTETLLLKAVCCYESLILKAEGKVESEFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFYYNAFHWAIKAFQEVLYVEPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDSNPCTLSSVEIQFHIAHLYETQRMYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNVDLLGDQATKESCAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKSCSNTSMLTGRIKVLQAQLCNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQAYKARHPNTEPILGLNETAISQQPLPVHMITHSQVDDQSSPAKRKRISSPAKYLEQLRTDRDNLNTTQKLMLQQLESQFVLMQQMRQTGQTTGIPNGPIADSSLPTNSLSSQQPHSAVPRVSSVSQPEVHSACFENPLSSGPFPARYILSGTSKPLGCTDTNLVGNNYLTRSGNNGNVPYLQQNTFTLPHNCTNLTSSTEEPWRKQLSNSTQGFNKGQNSHLPGSNDEQPSFSTDPALYLQAASTNIQTSHRMLPTSSVTQGTAFNHLSHIATSGDQQGICYTKESTPSGNRSSVPEISSHTEDKPNGCAGVKGLSNRVQQLMAEPICSPNSGDSTSPNFISDNPQISSLLIGKANDTMITGACDKVNSIHPESHTTTNNSVASLHSSIISTTALKSVDHTTTFGVTSISSSHIRLQTVNGKGLENSHSSKNTSLPMISRKPDSPIIPSMSVSIYSNSTEVLKACRNLDKNGLSNSHNLLDKCPPPKPPTSPYPPLPKDKLNPPTPSIYLESKRDAFFPPLHQFCINPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHTVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRMQHREYSDNESTSSDNTGRRRKGPFKTIKFGTNIDLSDDKKWKLQLLELTKLPAFVRVVSAGNLLSHLGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTASQYKLAVERYEWNKLQSVKSVVPMVHLSWNMARNIKVSDPKLFEMIKYCLMKILKQCLTLREALITAGKEVIWHGRTNDEPAHYCSICEVEVFDLLFVTNESNFQKTYIVHCQDCARKASGNLDNFVVLEEYKMEDLIQVYDQFTLAPSVSSSSS", "length": 1406, "header": "tr|A0ABI0NSF7-1|A0ABI0NSF7_BOVIN Isoform 1 of [histone H3]-trimethyl-L-lysine(27) demethylase OS=Bos taurus OX=9913 GN=LOC132344466 PE=3 SV=1 CANONICAL=A0ABI0NSF7-1" }, "locus": { "chromosome": "Y", "start_pos": 7623060, "end_pos": 7439647, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148273.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148273.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105993.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105993.1" } ] } }, { "isoform_ac": "A0ABI0NT23-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF7/entry#A0ABI0NT23-1", "sequence": { "sequence": "MKSCGVSLAAAAPAFSDEEKKMAAGKPRSKTKEGTLSLTAEEREELSGLDSLLFGFLNLHEDGAKTETLLLKAVCCYESLILKAEGKVESEFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFYYNAFHWAIKAFQEVLYVEPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDSNPCTLSSVEIQFHIAHLYETQRMYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNVDLLGDQATKESCAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKSCSNTSMLTGRIKVLQAYKARHPNTEPILGLNETAISQQPLPVHMITHSQVDDQSSPAKRKRISSPAKYLEQLRTDRDNLNTTQKLMLQQLESQFVLMQQMRQTGQTTGIPNGPIADSSLPTNSLSSQQPHSAVPRVSSVSQPEVHSACFENPLSSGPFPARYILSGTSKPLGCTDTNLVGNNYLTRSGNNGNVPYLQQNTFTLPHNCTNLTSSTEEPWRKQLSNSTQGFNKGQNSHLPGSNDEQPSFSTDPALYLQAASTNIQTSHRMLPTSSVTQGTAFNHLSHIATSGDQQGICYTKESTPSGNRSSVPEISSHTEDKPNGCAGVKGLSNRVQQLMAEPICSPNSGDSTSPNFISDNPQISSLLIGKANDTMITGACDKVNSIHPESHTTTNNSVASLHSSIISTTALKSVDHTTTFGVTSISSSHIRLQTVNGKGLENSHSSKNTSLPMISRKPDSPIIPSMSVSIYSNSTEVLKACRNLDKNGLSNSHNLLDKCPPPKPPTSPYPPLPKDKLNPPTPSIYLESKRDAFFPPLHQFCINPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHTVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRMQHREYSDNESTSSDNTGRRRKGPFKTIKFGTNIDLSDDKKWKLQLLELTKLPAFVRVVSAGNLLSHLGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTASQYKLAVERYEWNKLQSVKSVVPMVHLSWNMARNIKVSDPKLFEMIKYCLMKILKQCLTLREALITAGKEVIWHGRTNDEPAHYCSICEVEVFDLLFVTNESNFQKTYIVHCQDCARKASGNLDNFVVLEEYKMEDLIQVYDQFTLAPSVSSSSS", "length": 1361, "header": "tr|A0ABI0NT23-1|A0ABI0NT23_BOVIN Computationally mapped isoform of [histone H3]-trimethyl-L-lysine(27) demethylase OS=Bos taurus OX=9913 GN=LOC132344466 PE=3 SV=1 CANONICAL=A0ABI0NSF7-1" }, "locus": { "chromosome": "Y", "start_pos": 7623060, "end_pos": 7439647, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142486.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142486.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107515.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107515.1" } ] } }, { "isoform_ac": "A0ABI0P1X1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF7/entry#A0ABI0P1X1-1", "sequence": { "sequence": "MKSCGVSLAAAAPAFSDEEKKMAAGKPRSKTKEGTLSLTAEEREELSGLDSLLFGFLNLHEDGAKTETLLLKAVCCYESLILKAEGKVESEFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFYYNAFHWAIKAFQEVLYVEPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALIDSNPCTLSSVEIQFHIAHLYETQRMYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNVDLLGDQATKESCAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKSCSNTSMLTGRIKVLQAQLCNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQAYKARHPNTEPILGLNETAISQQPLPVHMITHSQVDDQSSPAKRKRISSPAKYLEQLRTDRDNLNTTQKLMLQQLESQFVLMQQGFNKGQNSHLPGSNDEQPSFSTDPALYLQAASTNIQTSHRMLPTSSVTQGTAFNHLSHIATSGDQQGICYTKESTPSGNRSSVPEISSHTEDKPNGCAGVKGLSNRVQQLMAEPICSPNSGDSTSPNFISDNPQISSLLIGKANDTMITGACDKVNSIHPESHTTTNNSVASLHSSIISTTALKSVDHTTTFGVTSISSSHIRLQTVNGKGLENSHSSKNTSLPMISRKPDSPIIPSMSVSIYSNSTEVLKACRNLDKNGLSNSHNLLDKCPPPKPPTSPYPPLPKDKLNPPTPSIYLESKRDAFFPPLHQFCINPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHTVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRMQHREYSDNESTSSDNTGRRRKGPFKTIKFGTNIDLSDDKKWKLQLLELTKLPAFVRVVSAGNLLSHLGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTASQYKLAVERYEWNKLQSVKSVVPMVHLSWNMARNIKVSDPKLFEMIKYCLMKILKQCLTLREALITAGKEVIWHGRTNDEPAHYCSICEVEVFDLLFVTNESNFQKTYIVHCQDCARKASGNLDNFVVLEEYKMEDLIQVYDQFTLAPSVSSSSS", "length": 1278, "header": "tr|A0ABI0P1X1-1|A0ABI0P1X1_BOVIN Computationally mapped isoform of [histone H3]-trimethyl-L-lysine(27) demethylase OS=Bos taurus OX=9913 GN=LOC132344466 PE=3 SV=1 CANONICAL=A0ABI0NSF7-1" }, "locus": { "chromosome": "Y", "start_pos": 7623060, "end_pos": 7439647, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154558.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154558.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105288.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105288.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 945, "start_aa": "Thr", "end_pos": 945, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr945", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSF7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSF7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF7" } ], "pmid": "" }, { "name": "histone H3K27me2/H3K27me3 demethylase activity", "id": "GO:0071558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071558", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSF7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1031, "end_pos": 1033, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1068, "end_pos": 1070, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1351, "end_pos": 1353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 649, "end_pos": 651, "annotation": "n_glycosylation_sequon" }, { "start_pos": 731, "end_pos": 733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 796, "end_pos": 798, "annotation": "n_glycosylation_sequon" }, { "start_pos": 819, "end_pos": 821, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, "end_pos": 874, "annotation": "n_glycosylation_sequon" }, { "start_pos": 897, "end_pos": 899, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60224", "name": "", "equation": "N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(27)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3N2E9-1", "G3N346-1", "A0ABI0NSF7-1" ], "evidence": [ { "id": "60224", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60224" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0ABI0NSF7", "gene_name": "LOC132344466", "activity": [ { "ec_number": "1.14.11.68", "activity": "N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(27)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "A0ABI0NSF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF7" } ] }, { "ec_number": "1.14.11.68", "activity": "", "evidence": [ { "id": "A0ABI0NSF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF7" } ] } ] }, { "uniprot_ac": "G3N2E9", "gene_name": "KDM6A", "activity": [ { "ec_number": "1.14.11.68", "activity": "N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(27)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "G3N2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2E9" } ] }, { "ec_number": "1.14.11.68", "activity": "", "evidence": [ { "id": "G3N2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2E9" } ] } ] }, { "uniprot_ac": "G3N346", "gene_name": "KDM6B", "activity": [ { "ec_number": "1.14.11.68", "activity": "N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(27)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "G3N346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N346" } ] }, { "ec_number": "1.14.11.68", "activity": "", "evidence": [ { "id": "G3N346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N346" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NSF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSF7" }, { "id": "PS51184", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51184" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "JmjC", "eco_id": "ECO_0000259", "start_pos": 1100, "end_pos": 1263, "start_aa": "Lys", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.11.68", "ec_name": "N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(27)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "1.14.11.68", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.68" }, { "id": "1.14.11.68", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.68" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 945 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": 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"reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG4", "locus": {} } ], "crossref": [ { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037264", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037264", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19879", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19879", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19879:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19879:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", 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"MKRMAVSCYLKRRQYGDADGPLKQGLRLSQSTEEMAASLTVQSESGCANIVSAAPCQAEPQQYEVQFGRLWNFLTDSDSQHSHEVMPLLYPLFVYLHLTLIQNSPKSTAESFYSRFHGMFLQNTTQIVQDILSNFRLRAFLDNKYVVRLQEDSYSYLLRYLQSDNNTALCRILAWHIHLDVQPAKRMDYQLYASGGFSHGEGSGLEPTDMPAPILQNKAALELLQKSIKRVKDSPPSLTTIYFYAFYNTEQLLNTAEVSPNSKLLAAGFDNSCIKLWSLCSEKLKSKPHQVDVSRIHLACDFLEEEDDEDDNAGTEMKVLRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPHSLYFASGSHDRTARLWSFDRTYPLRIFAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSTQQGNSVRLFTGHRGPVLSLAFSPNSKYLASAGEDQRLKLWDLASGTLYKELRGHTDSITSLTFSSDSSLIASASMDNSVRVWDIRSTHCSTPADGSSSELLGVYTSQISKVLSVQFMACNLLLVTGIPQENQEH", "length": 571, "header": "tr|A0ABI0NSG4-1|A0ABI0NSG4_BOVIN Isoform 1 of TFIID subunit TAF5 NTD2 domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NSG4-1" }, "locus": { "chromosome": "3", "start_pos": 103587396, "end_pos": 103585226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151220.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151220.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105845.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105845.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSG4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NSG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSG4" }, { "id": "PF04494", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04494" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TFIID subunit TAF5 NTD2", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 176, "start_aa": "Ala", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 165, "end_pos": 167 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NSH1-1", "uniprot_ac": "A0ABI0NSH1", "uniprot_id": "A0ABI0NSH1_BOVIN", "mass": { "chemical_mass": 60967.0, "monoisotopic_mass": 60967.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NSH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May function as a transcription factor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSH1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH1#function" }, { "database": "UniProtKB", "id": "ARBA00003729", "url": "https://www.uniprot.org/uniprotkb/ARBA00003729#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSH1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH1", "locus": {} } ], "crossref": [ { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NSH1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSH1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPVIIEPLSKADSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNRIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYKQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPG", "length": 543, "header": "tr|A0ABI0NSH1-1|A0ABI0NSH1_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NSH1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NSH1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSH1/entry#A0ABI0NSH1-1", "sequence": { "sequence": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377055" }, "gene_names": [ { "name": "OR51A42", "type": "recommended", "evidence": [ { "id": "A0ABI0NSN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSN7" } ] }, { "name": "OR51A42", "type": "synonym", "evidence": [ { "id": "NP_001377055", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377055" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NSN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSN7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 51 subfamily A member 42", "type": "synonym", "evidence": [ { "id": "NP_001377055", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377055" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"length": 2568, "header": "tr|A0ABI0NSR1-1|A0ABI0NSR1_BOVIN Isoform 1 of ubiquitinyl hydrolase 1 OS=Bos taurus OX=9913 GN=USP9Y PE=3 SV=1 CANONICAL=A0ABI0NSR1-1" }, "locus": { "chromosome": "Y", "start_pos": 7247073, "end_pos": 7121519, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151334.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151334.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106061.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106061.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 45, "start_aa": "Thr", "end_pos": 45, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr45", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSR1" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSR1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1215, "end_pos": 1217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1631, "end_pos": 1633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2147, "end_pos": 2149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2238, "end_pos": 2240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2261, "end_pos": 2263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2439, "end_pos": 2441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2447, "end_pos": 2449, "annotation": 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"database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300", "url": 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"MGASSKVGRSPKGTMAALGITVALLVWMATLLFISIWKHIYSSWKLPPGPFPLPIIGNLLQLDIKNIPKSFTRLAERYGPVFTLYLGSQRAVVVHGYKPVKEVLLDYKNEFSGRGENPGFQMHKNNGIIFNNGSTWRDTRRFSLTTLRDLGMGKQGNEQRIQREAHFLLEVLRKTQGQPFDPTFVVGFAPYNVISDILFHKRFDYKDQTSLRLMSLFNENFYLLSSPWIQLYNNFPDYLQYLPGSHRKLLKNVSEVKSYALERVKDHQKSLEPSCPRGFLDTMLIEMAKERHSVDPMYTLENIAVTVADLLFAGTETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPSRIPAVKDRLDMPYLDAVVHEIQRFIDLLPSNLLHEATQDTVFRGYVIPKGTVVIPTLDSVLHDRQEFPEPEKFKPEHFLNENGKFKYSDHFKAFSAGKRVCVGEGLARMELFLLLAAILQHFNLKSLVDPKDIDLSPIAIGFGKIPPRYKLCLIPRSKV", "length": 509, "header": "tr|A0ABI0NSS2-1|A0ABI0NSS2_BOVIN Isoform 1 of Cytochrome P450 2E1 OS=Bos taurus OX=9913 GN=CYP2E1 PE=3 SV=1 CANONICAL=A0ABI0NSS2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NSS2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSS2/entry#A0ABI0NSS2-1", "sequence": { "sequence": "MGASSKVGRSPKGTMAALGITVALLVWMATLLFISIWKHIYSSWKLPPGPFPLPIIGNLLQLDIKNIPKSFTRLAERYGPVFTLYLGSQRAVVVHGYKPVKEVLLDYKNEFSGRGENPGFQMHKNNGIIFNNGSTWRDTRRFSLTTLRDLGMGKQGNEQRIQREAHFLLEVLRKTQGQPFDPTFVVGFAPYNVISDILFHKRFDYKDQTSLRLMSLFNENFYLLSSPWIQLYNNFPDYLQYLPGSHRKLLKNVSEVKSYALERVKDHQKSLEPSCPRGFLDTMLIEMAKERHSVDPMYTLENIAVTVADLLFAGTETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPSRIPAVKDRLDMPYLDAVVHEIQRFIDLLPSNLLHEATQDTVFRGYVIPKGTVVIPTLDSVLHDRQEFPEPEKFKPEHFLNENGKFKYSDHFKAFSAGKRVCVGEGLARMELFLLLAAILQHFNLKSLVDPKDIDLSPIAIGFGKIPPRYKLCLIPRSKV", "length": 509, "header": "tr|A0ABI0NSS2-1|A0ABI0NSS2_BOVIN Isoform 1 of Cytochrome P450 2E1 OS=Bos taurus OX=9913 GN=CYP2E1 PE=3 SV=1 CANONICAL=A0ABI0NSS2-1" }, "locus": { "chromosome": "26", "start_pos": 50175881, "end_pos": 50165568, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152508.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152508.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107233.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107233.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 306, "start_aa": "Thr", "end_pos": 306, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr306", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSS2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSS2" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSS2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSS2" } ], "pmid": "" }, { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSS2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSS2" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSS2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSS2" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSS2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSS2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSS2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSS2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSS2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSS2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSS2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSS2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17149", "name": "", "equation": "an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAF6DLT2-1", "P79102-1", "A0A3S5ZP79-1", "O18963-1", "Q01361-1", "P22779-1", "E1B8U6-1", "A0A3Q1LK48-1", "A0AAA9SC04-1", "A0ABI0NSS2-1" ], "evidence": [ { "id": "17149", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17149" } ] }, { "id": "39751", "name": "", "equation": "dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 11-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3S5ZP79-1", "O18963-1", "A0ABI0NSS2-1" ], "evidence": [ { "id": "39751", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/39751" } ] }, { "id": "39787", "name": "", "equation": "(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3S5ZP79-1", "O18963-1", "A0ABI0NSS2-1" ], "evidence": [ { "id": "39787", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/39787" } ] }, { "id": "50076", "name": "", "equation": "(5Z,8Z,11Z)-eicosatrienoate + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3S5ZP79-1", "O18963-1", "A0ABI0NSS2-1" ], "evidence": [ { "id": "50076", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50076" } ] }, { "id": "50088", "name": "", "equation": "(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 21-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3S5ZP79-1", "O18963-1", "A0ABI0NSS2-1" ], "evidence": [ { "id": "50088", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50088" } ] }, { "id": "50096", "name": "", "equation": "tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 13-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3S5ZP79-1", "O18963-1", "A0ABI0NSS2-1" ], "evidence": [ { "id": "50096", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50096" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LK48", "gene_name": "CYP3A76", "activity": [ { "ec_number": "1.14.14.-", "activity": "", "evidence": [ { "id": "A0A3Q1LK48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK48" } ] } ] }, { "uniprot_ac": "A0A3S5ZP79", "gene_name": "CYP2C87", "activity": [ { "ec_number": "1.14.13.n7", "activity": "4-nitrophenol + NADPH + O2 + H(+) = 4-nitrocatechol + NADP(+) + H2O.", "evidence": [ { "id": "A0A3S5ZP79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZP79" } ] }, { "ec_number": "1.14.14.1", "activity": "an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+).", "evidence": [ { "id": "A0A3S5ZP79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZP79" } ] }, { "ec_number": "1.14.13.n7", "activity": "", "evidence": [ { "id": "A0A3S5ZP79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZP79" } ] }, { "ec_number": "1.14.14.1", "activity": "", "evidence": [ { "id": "A0A3S5ZP79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZP79" } ] }, { "ec_number": "1.14.14.-", "activity": "", "evidence": [ { "id": "A0A3S5ZP79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZP79" } ] } ] }, { "uniprot_ac": "A0AAA9SC04", "gene_name": "CYP2A13", "activity": [ { "ec_number": "1.14.14.1", "activity": "an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+).", "evidence": [ { "id": "A0AAA9SC04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC04" } ] }, { "ec_number": "1.14.14.1", "activity": "", "evidence": [ { "id": "A0AAA9SC04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC04" } ] } ] }, { "uniprot_ac": "A0AAF6DLT2", "gene_name": "CYP2S1", "activity": [ { "ec_number": "1.14.14.1", "activity": "an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+).", "evidence": [ { "id": "A0AAF6DLT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLT2" } ] }, { "ec_number": "1.14.14.1", "activity": "", "evidence": [ { "id": "A0AAF6DLT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLT2" } ] } ] }, { "uniprot_ac": "A0ABI0NSS2", "gene_name": "CYP2E1", "activity": [ { "ec_number": "1.14.13.n7", "activity": "4-nitrophenol + NADPH + O2 + H(+) = 4-nitrocatechol + NADP(+) + H2O.", "evidence": [ 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSNQPSLALHGIPVIYCCLFSKPHPKLSAIKQHPFYQRSPLRDFEGGGRSRKGSERKGEPALKGKCSLRNGLALSSPAAQTPAAASTNWSGRPSSDPMADCCTPIKKLCWWHGAGSTADFQKIIQERCDTYTQTIRPGSRSRNCQAIRQAFMSTFISKDPCKATKEDYNSLINLAPPTVPCGQQVFWSKTKELAHEYVKRQRLMTLEDTLLGYLADGLSWCGEPGSSDLNIWSCPDWRKDCRTNYLSVFWEVLSERFAESACSTVRVVLNGSLENAFDSMSIFGRVEAPNLRPQVELEAWLVHDTGKPPSDSCSGSSIRKLKSILDGRNVKFRCMDNLSRDQFLQRS", "length": 348, "header": "tr|A0ABI0NSS5-1|A0ABI0NSS5_BOVIN Isoform 1 of ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 OS=Bos taurus OX=9913 GN=LOC101907622 PE=3 SV=1 CANONICAL=A0ABI0NSS5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NSS5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSS5/entry#A0ABI0NSS5-1", "sequence": { "sequence": 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"https://www.ncbi.nlm.nih.gov/protein/XP_059736023" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NST8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NST8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MDFIC2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NST8", "locus": { "chromosome": "22", "start_pos": 31399636, "end_pos": 31286348, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000064171", "url": "https://www.ensembl.org/id/ENSBTAG00000064171" } ] } } ], "crossref": [ { "id": "104975541", "url": "https://www.ncbi.nlm.nih.gov/gene/104975541", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026134", "database": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:782109", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:782109", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR15390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15390:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15390:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02070", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02070", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178082", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178082", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NSV7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSV7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTQ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ65", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ65-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3M0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3M0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRAASRRPEPPAGHVAAGSPLLLLLLLSCCADACGGAPVLPQGLQPEQELQLWKQINDACLSLLSMHPQPQASNALEEICLTIMRTLPKPQETDEKDNTKRFLFHYSKTQKLGNSNVVSSVLHPLLQLVPQLHERRMKRFRLDEEFQGPIASQSRRYFLFRPRNGRRSEGYI", "length": 173, "header": "tr|A0ABI0NSV7-1|A0ABI0NSV7_BOVIN Isoform 1 of Neuromedin U OS=Bos taurus OX=9913 GN=NMU PE=3 SV=1 CANONICAL=A0ABI0NSV7-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NSV7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV7/entry#A0ABI0NSV7-1", "sequence": { "sequence": "MLRAASRRPEPPAGHVAAGSPLLLLLLLSCCADACGGAPVLPQGLQPEQELQLWKQINDACLSLLSMHPQPQASNALEEICLTIMRTLPKPQETDEKDNTKRFLFHYSKTQKLGNSNVVSSVLHPLLQLVPQLHERRMKRFRLDEEFQGPIASQSRRYFLFRPRNGRRSEGYI", "length": 173, "header": "tr|A0ABI0NSV7-1|A0ABI0NSV7_BOVIN Isoform 1 of Neuromedin U OS=Bos taurus OX=9913 GN=NMU PE=3 SV=1 CANONICAL=A0ABI0NSV7-1" }, "locus": { "chromosome": "6", "start_pos": 71061233, "end_pos": 71033013, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149610.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149610.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107315.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107315.1" } ] } }, { "isoform_ac": "A0ABI0NTQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV7/entry#A0ABI0NTQ2-1", "sequence": { "sequence": "MLRAASRRPEPPAGHVAAGSPLLLLLLLSCCADACGGAPVLPQGLQPEQELQLWKQINDACLSLLSMHPQPQASNALEEICLTIMRTLPKPQETDEKDNTKRFLFHYSKTQKLGNSNVVEEFQGPIASQSRRYFLFRPRNGRRSEGYI", "length": 148, "header": "tr|A0ABI0NTQ2-1|A0ABI0NTQ2_BOVIN Computationally mapped isoform of Neuromedin U OS=Bos taurus OX=9913 GN=NMU PE=3 SV=1 CANONICAL=A0ABI0NSV7-1" }, "locus": { "chromosome": "6", "start_pos": 71061233, "end_pos": 71033013, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148197.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148197.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106954.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106954.1" } ] } }, { "isoform_ac": "A0ABI0NZ65-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV7/entry#A0ABI0NZ65-1", "sequence": { "sequence": "MLRAASRRPEPPAGHVAAGSPLLLLLLLSCCADACGGAPVLPQGLQPEQELQLWKQINDACLSLLSMHPQPQASNALEEICLTIMRTLPKPQSSVLHPLLQLVPQLHERRMKRFRLDEEFQGPIASQSRRYFLFRPRNGRRSEGYI", "length": 146, "header": "tr|A0ABI0NZ65-1|A0ABI0NZ65_BOVIN Computationally mapped isoform of Neuromedin U OS=Bos taurus OX=9913 GN=NMU PE=3 SV=1 CANONICAL=A0ABI0NSV7-1" }, "locus": { "chromosome": "6", "start_pos": 71061233, "end_pos": 71033013, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137060.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137060.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105455.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105455.1" } ] } }, { "isoform_ac": "A0ABI0P3M0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV7/entry#A0ABI0P3M0-1", "sequence": { "sequence": "MLRAASRRPEPPAGHVAAGSPLLLLLLLSCCADACGGAPVLPQGLQPEQELQLWKQASNALEEICLTIMRTLPKPQETDEKDNTKRFLFHYSKTQKLGNSNVVSSVLHPLLQLVPQLHERRMKRFRLDEEFQGPIASQSRRYFLFRPRNGRRSEGYI", "length": 157, "header": "tr|A0ABI0P3M0-1|A0ABI0P3M0_BOVIN Computationally mapped isoform of Neuromedin U OS=Bos taurus OX=9913 GN=NMU PE=3 SV=1 CANONICAL=A0ABI0NSV7-1" }, "locus": { "chromosome": "6", "start_pos": 71061233, "end_pos": 71033013, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150045.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150045.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107589.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107589.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:782109", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:782109", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSV7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of smooth muscle contraction", "id": "GO:0006940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006940", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSV7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "neuromedin U receptor binding", "id": "GO:0042922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042922", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSV7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NSV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV7" }, { "id": "SM00084", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00084" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Neuromedin U C-terminal", "eco_id": "ECO_0000259", "start_pos": 141, "end_pos": 165, "start_aa": "Phe", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NSV9-1", "uniprot_ac": "A0ABI0NSV9", "uniprot_id": "A0ABI0NSV9_BOVIN", "mass": { "chemical_mass": 60887.0, "monoisotopic_mass": 60887.0 }, "refseq": { "ac": "XP_059740197", "name": "zinc finger protein 280B-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740197" }, "gene_names": [ { "name": "LOC132344526", "type": "recommended", "evidence": [ { "id": "A0ABI0NSV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV9" } ] }, { "name": "LOC132344527", "type": "synonym", "evidence": [ { "id": "XP_059740197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740197" }, { "id": "A0ABI0NSV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV9" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NSV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 280B-like", "type": "synonym", "evidence": [ { "id": "XP_059740197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740197" } ] } ], "function": [ { "annotation": "May function as a transcription factor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSV9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV9#function" }, { "database": "UniProtKB", "id": "ARBA00003729", "url": "https://www.uniprot.org/uniprotkb/ARBA00003729#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSV9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC132344526", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV9", "locus": {} } ], "crossref": [ { "id": "132344527", "url": "https://www.ncbi.nlm.nih.gov/gene/132344527", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059740197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740197", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NSV9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSV9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRCGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLHCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYKQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPG", "length": 543, "header": "tr|A0ABI0NSV9-1|A0ABI0NSV9_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=LOC132344526 PE=4 SV=1 CANONICAL=A0ABI0NSV9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NSV9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSV9/entry#A0ABI0NSV9-1", "sequence": { "sequence": 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"name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0ABI0NTB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTB7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTB7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTB7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTB7", "locus": {} } ], "crossref": [ { "id": "IPR052477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46272", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46272", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46272:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46272:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0ABI0NSZ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTB7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTB7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKSPPANAGDRGSIPGSGRSLGERNGSPLQCPRLENPMEEGAWRAAVHGVAKSRKELSDCTARSLFQGWVAISGHRGVTQEQSPGAEFKTQLRKAGLEVGLQPAAQHPGAWRGEDPLSGGRGRPLISHLVLTARSAPQLALEQRCRELRARGRRLEETLPRRVSSEQQREALGLLCRVHELELEKAEMQSQALLRDGALRHRREALRRLEQRLSLCEEIIRAQRQLIQDGNLAVPQHLKELYEVYLREHEEGNLERATMMDRLASRALQDSALPKMSPPGTVPTPEESDLESVKMLNSESPHQHGSFLPLLGTESEANHLFKASSRAWQAKGSCLPTPPPILAGTLVTQEVTATQVGLNGQINSSPGSIENLSEIPLSHKGRKETAADTKSITGKAARHRSQALGAEGRQLLAPTMKQSSLSLHSLGETDDVWPPRPLACKRPPSPTLQHTASEDSLSSSTGEAPSRAVERHGDGPCPPLQGQKKSPRNKREESLEAKRKRRSQAFEVTGQGVSLEGQELGVSGPLPCRVLKAGLLQRPQGTTSCAPLSMECPPTEPNISLYQIPTQLPAHLALQPTQLSRPKMHVAGPRPVENHTEEQRMPVVGHLTPTIRPLGKTTLPMAKVKLPPCQSLGPEDTSPVAAPSNPGDVSERVARMPRLPYGTSTQGKNGRLGHN", "length": 676, "header": "tr|A0ABI0NTB7-1|A0ABI0NTB7_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NTB7-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NSZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTB7/entry#A0ABI0NSZ1-1", "sequence": { "sequence": "EISKHLLSTGGSVVKHPPANSGDAGSVPGSGRSPGVGNGYPLQYSFLENPMDRGAWRVTESDTSEELTLCVCGLSRSFKTQLRKAGLEVGLQPAAQHPGAWRGEDPLSGGRGRPLISHLVLTARSAPQLALEQRCRELRARGRRLEETLPRRVSSEQQREALGLLCRVHELELEKAEMQSQALLRDGALRHRREALRRLEQRLSLCEEIIRAQRQLIQDGNLAVPQHLKELYEVYLREHEEGNLERATMMDRLASRALQDSALPKMSPPGTVPTPEESDLESVKMLNSESPHQHGSFLPLLGTESEANHLFKASSRAWQAKGSCLPTPPPILAGTLVTQEVTATQVGLNGQINSSPGSIENLSEIPLSHKGRKETAADTKSITGKAARHRSQALGAEGRQLLAPTMKQSSLSLHSLGETDDVWPPRPLACKRPPSPTLQHTASEDSLSSSTGEAPSRAVERHGDGPCPPLQGQKKSPRNKREESLEAKRKRRSQAFEVTGQGIPTQLPAHLALQPTQLSRPKMHVAGPRPVENHTEEQRMPVVGHLTPTIRPLGKTTLPMAKVKLPPCQSLGPEDTSPVAAPSNPGDVSERVARMPRLPYGTSTQGKNGRLGHN", "length": 614, "header": "tr|A0ABI0NSZ1-1|A0ABI0NTB7_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NTB7-1" }, "locus": { "chromosome": "19", "start_pos": 57072644, "end_pos": 57068191, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148287.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148287.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107435.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107435.1" } ] } }, { "isoform_ac": "A0ABI0NTB7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTB7/entry#A0ABI0NTB7-1", "sequence": { "sequence": "MVKSPPANAGDRGSIPGSGRSLGERNGSPLQCPRLENPMEEGAWRAAVHGVAKSRKELSDCTARSLFQGWVAISGHRGVTQEQSPGAEFKTQLRKAGLEVGLQPAAQHPGAWRGEDPLSGGRGRPLISHLVLTARSAPQLALEQRCRELRARGRRLEETLPRRVSSEQQREALGLLCRVHELELEKAEMQSQALLRDGALRHRREALRRLEQRLSLCEEIIRAQRQLIQDGNLAVPQHLKELYEVYLREHEEGNLERATMMDRLASRALQDSALPKMSPPGTVPTPEESDLESVKMLNSESPHQHGSFLPLLGTESEANHLFKASSRAWQAKGSCLPTPPPILAGTLVTQEVTATQVGLNGQINSSPGSIENLSEIPLSHKGRKETAADTKSITGKAARHRSQALGAEGRQLLAPTMKQSSLSLHSLGETDDVWPPRPLACKRPPSPTLQHTASEDSLSSSTGEAPSRAVERHGDGPCPPLQGQKKSPRNKREESLEAKRKRRSQAFEVTGQGVSLEGQELGVSGPLPCRVLKAGLLQRPQGTTSCAPLSMECPPTEPNISLYQIPTQLPAHLALQPTQLSRPKMHVAGPRPVENHTEEQRMPVVGHLTPTIRPLGKTTLPMAKVKLPPCQSLGPEDTSPVAAPSNPGDVSERVARMPRLPYGTSTQGKNGRLGHN", "length": 676, "header": "tr|A0ABI0NTB7-1|A0ABI0NTB7_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NTB7-1" }, "locus": { "chromosome": "19", "start_pos": 57072087, "end_pos": 57068191, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140149.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140149.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107752.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107752.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 285, "start_aa": "Thr", "end_pos": 285, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr285", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTB7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTB7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTB7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 285 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 26, "end_pos": 28 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 559, "end_pos": 561 }, { "start_pos": 595, "end_pos": 597 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NSZ2-1", "uniprot_ac": "A0ABI0NSZ2", "uniprot_id": "A0ABI0NSZ2_BOVIN", "mass": { "chemical_mass": 92277.0, "monoisotopic_mass": 92277.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "MAGE domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NSZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSZ2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NSZ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSZ2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSZ2", "locus": {} } ], "crossref": [ { "id": "IPR002190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11736:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11736:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12440", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12440", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NSZ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRGRKSKHCAHEKRHQDRAETQGLHDHATTSGEEETTFSSPPDSESTPSSSSAAGTLKGRQGAQGTTSAAAGAICKRSGVGGTARSRSGVGAKGQVQEGENSSQASAAAESCHTDLTRESESLLRYMLFKYMMRELIKRSEMLKVIHRSYRKQFPEILRRDSECMELEFGLVLKEVRPNNHCYTLVSNLDLSDSESMRGDCRLPKNGLLMPLLGVTYLNGHRASEEDIWKFLNMLSIYDGRRHFISGDTGKLITQDLVQEVYLEYRQVPGSDPPRYEFLWGPNTLTQNSKTKVLQILTRVNDSAPDTLQPRYEDSWREEVESSRARAAAGTGRSASASTGPSALPVLAFLPRPGLALLLQLGLTCLPRPGPALLPRTVLAILPRPDMSHWPRPDMAHRPQPGLKYLPGPVLALLPQPVLALMPRPVLALMPQPVLALLPRSVLALLPWPDLAFLVQPGLALRPQPVLTLLLWPVLTLLPWPELALLLQPRLTCLPGPGLAFLPQAVLAPLPWPDLAILLQPGLAFLPQPVLAPLPWLDLAHMLQTGQALWPQPLLIFLPVPRLTLLPQPVLALRPWPVLALLLQPRLALWPWPVLTYLPGPGLALLPQPVLALWPWPVLALLLQPGLAFWPWPVLTYLPGPGLALLPQPVLALRPWPVLALLLQPGLALWPWPVLTCLPGPGLALRPQPVLTLLPWPELALLFQPGLTCLPGPGLAFLPQAVQAPLSWPGLALLLQPGLALRPRPVLTPLPWPDFALLLQPVLALLPRPVLTLLPWPHLALLLLPGLAVWRQLGLTFLPWPGVAFLPRPSQVLLPRPVLPLLPRPVPSPGPNSATHLAPGVV", "length": 843, "header": "tr|A0ABI0NSZ2-1|A0ABI0NSZ2_BOVIN Isoform 1 of MAGE domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NSZ2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NSZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSZ2/entry#A0ABI0NSZ2-1", "sequence": { "sequence": "MPRGRKSKHCAHEKRHQDRAETQGLHDHATTSGEEETTFSSPPDSESTPSSSSAAGTLKGRQGAQGTTSAAAGAICKRSGVGGTARSRSGVGAKGQVQEGENSSQASAAAESCHTDLTRESESLLRYMLFKYMMRELIKRSEMLKVIHRSYRKQFPEILRRDSECMELEFGLVLKEVRPNNHCYTLVSNLDLSDSESMRGDCRLPKNGLLMPLLGVTYLNGHRASEEDIWKFLNMLSIYDGRRHFISGDTGKLITQDLVQEVYLEYRQVPGSDPPRYEFLWGPNTLTQNSKTKVLQILTRVNDSAPDTLQPRYEDSWREEVESSRARAAAGTGRSASASTGPSALPVLAFLPRPGLALLLQLGLTCLPRPGPALLPRTVLAILPRPDMSHWPRPDMAHRPQPGLKYLPGPVLALLPQPVLALMPRPVLALMPQPVLALLPRSVLALLPWPDLAFLVQPGLALRPQPVLTLLLWPVLTLLPWPELALLLQPRLTCLPGPGLAFLPQAVLAPLPWPDLAILLQPGLAFLPQPVLAPLPWLDLAHMLQTGQALWPQPLLIFLPVPRLTLLPQPVLALRPWPVLALLLQPRLALWPWPVLTYLPGPGLALLPQPVLALWPWPVLALLLQPGLAFWPWPVLTYLPGPGLALLPQPVLALRPWPVLALLLQPGLALWPWPVLTCLPGPGLALRPQPVLTLLPWPELALLFQPGLTCLPGPGLAFLPQAVQAPLSWPGLALLLQPGLALRPRPVLTPLPWPDFALLLQPVLALLPRPVLTLLPWPHLALLLLPGLAVWRQLGLTFLPWPGVAFLPRPSQVLLPRPVLPLLPRPVPSPGPNSATHLAPGVV", "length": 843, "header": "tr|A0ABI0NSZ2-1|A0ABI0NSZ2_BOVIN Isoform 1 of MAGE domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NSZ2-1" }, "locus": { "chromosome": "NKLS02000433.1", "start_pos": 30778, "end_pos": 28250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148678.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148678.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107393.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107393.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NSZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSZ2" }, { "id": "PS50838", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50838" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MAGE", "eco_id": "ECO_0000259", "start_pos": 117, "end_pos": 316, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 302, "end_pos": 304 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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] }, { "id": "PTHR11875", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11875", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00956", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00956", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NT03", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT03-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NT08-1", "uniprot_ac": "A0ABI0NT08", "uniprot_id": "A0ABI0NT08_BOVIN", "mass": { "chemical_mass": 55971.0, "monoisotopic_mass": 55971.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Melanoma antigen preferentially expressed in tumors", "type": "recommended", "evidence": [ { "id": "A0ABI0NT08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT08/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT08", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT08" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT08", "locus": {} } ], "crossref": [ { "id": "IPR026271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14224:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14224:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NT08", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT08-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTT2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTT2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUT0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUT0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUT0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKFTMGVRAPPRLLELASQSLLQNEALAIVALEELPTELFPPLFMAAFAGRHTQALKAMVQAWPFPCLPLGALMKDHQPHLETFQAVLDSLDILLGQEVRPRRWKLQVLDLRQNTHQDFWTLWSGIKASVCSLLEPEPAQPMQKRCKVEAQVVLKPAQAPVEVLVDLCLKEDTLDETISYLLKKAKQRRSLLHLRCQKLRIFTMPMQSIRRILKVVQLDSIQDLEVNCIWKLATLGRFVPHLGRMGNLRRLLLSRIHILPRTTPDQEEHFIDQLTIQFLNLPHLQKLYLDSISFLEGRLHQVLRCLKTPLETLWITNCLISESDLAYLSQCPSVSQLKDLGLSGVNLTSLSLEPLKVLIEWTSATLQDLDLDECGIMDSQFSALLPALSCCSQLTTFSFCGNPISMAVLESLLHHTMGLSKLSHVLYPSPLESYEDVRGTLHLGLLAQLHARLKRLLCESGRSSMVWVSASPCPHCGEQIFYDTEPILCPCYMPA", "length": 495, "header": "tr|A0ABI0NT08-1|A0ABI0NT08_BOVIN Isoform 1 of Melanoma antigen preferentially expressed in tumors OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NT08-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NT08-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT08/entry#A0ABI0NT08-1", "sequence": { "sequence": "MKFTMGVRAPPRLLELASQSLLQNEALAIVALEELPTELFPPLFMAAFAGRHTQALKAMVQAWPFPCLPLGALMKDHQPHLETFQAVLDSLDILLGQEVRPRRWKLQVLDLRQNTHQDFWTLWSGIKASVCSLLEPEPAQPMQKRCKVEAQVVLKPAQAPVEVLVDLCLKEDTLDETISYLLKKAKQRRSLLHLRCQKLRIFTMPMQSIRRILKVVQLDSIQDLEVNCIWKLATLGRFVPHLGRMGNLRRLLLSRIHILPRTTPDQEEHFIDQLTIQFLNLPHLQKLYLDSISFLEGRLHQVLRCLKTPLETLWITNCLISESDLAYLSQCPSVSQLKDLGLSGVNLTSLSLEPLKVLIEWTSATLQDLDLDECGIMDSQFSALLPALSCCSQLTTFSFCGNPISMAVLESLLHHTMGLSKLSHVLYPSPLESYEDVRGTLHLGLLAQLHARLKRLLCESGRSSMVWVSASPCPHCGEQIFYDTEPILCPCYMPA", "length": 495, "header": "tr|A0ABI0NT08-1|A0ABI0NT08_BOVIN Isoform 1 of Melanoma antigen preferentially expressed in tumors OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NT08-1" }, "locus": { "chromosome": "Y", "start_pos": 16786271, "end_pos": 16782880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150483.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150483.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106336.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106336.1" } ] } }, { "isoform_ac": "A0ABI0NTT2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT08/entry#A0ABI0NTT2-1", "sequence": { "sequence": "MGVRAPPRLLELASQSLLQNEALAIVALEELPTELFPPLFMAAFAGRHTQALKAMVQAWPFPCLPLGALMKDHQPHLETFQAVLDSLDILLGQEVRPRRWKLQVLDLRQNTHQDFWTLWSGIKASVCSLLEPEPAQPMQKRCKVEAQVVLKPAQAPVEVLVDLCLKEDTLDETISYLLKKAKQRRSLLHLRCQKLRIFTMPMQSIRRILKVVQLDSIQDLEVNCIWKLATLGRFVPHLGRMGNLRRLLLSRIHILPRTTPDQEEHFIDQLTIQFLNLPHLQKLYLDSISFLEGRLCLKTPLETLWITNCLISESDLAYLSQCPSVSQLKDLGLSGVNLTSLSLEPLKVLIEWTSATLQDLDLDECGIMDSQFSALLPALSCCSQLTTFSFCGNPISMAVLESLLHHTMGLSKLSHVLYPSPLESYEDVRGTLHLGLLAQLHARLKRLLCESGRSSMVWVSASPCPHCGDVNHWVSSVISDHDSPL", "length": 485, "header": "tr|A0ABI0NTT2-1|A0ABI0NTT2_BOVIN Computationally mapped isoform of Melanoma antigen preferentially expressed in tumors OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NT08-1" }, "locus": { "chromosome": "Y", "start_pos": 16786619, "end_pos": 16783304, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141073.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141073.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106861.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106861.1" } ] } }, { "isoform_ac": "A0ABI0NUT0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT08/entry#A0ABI0NUT0-1", "sequence": { "sequence": "MGVRAPPRLLELASQSLLQNEALAIVALEELPTELFPPLFMAAFAGRHTQALKAMVQAWPFPCLPLGALMKDHQPHLETFQAVLDSLDILLGQEVRPRRWKLQVLDLRQNTHQDFWTLWSGIKASVCSLLEPEPAQPMQKRCKVEAQVVLKPAQAPVEVLVDLCLKEDTLDETISYLLKKAKQRRSLLHLRCQKLRIFTMPMQSIRRILKVVQLDSIQDLEVNCIWKLATLGRFVPHLGRMGNLRRLLLSRIHILPRTTPDQEEHFIDQLTIQFLNLPHLQKLYLDSISFLEGRLHQVLRCLKTPLETLWITNCLISESDLAYLSQCPSVSQLKDLGLSGVNLTSLSLEPLKVLIEWTSATLQDLDLDECGIMDSQFSALLPALSCCSQLTTFSFCGNPISMAVLESLLHHTMGLSKLSHVLYPSPLESYEDVRGTLHLGLLAQLHARLKRLLCESGRSSMVWVSASPCPHCGDLHLRPCCCCC", "length": 484, "header": "tr|A0ABI0NUT0-1|A0ABI0NUT0_BOVIN Computationally mapped isoform of PRAME nuclear receptor transcriptional regulator OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NT08-1" }, "locus": { "chromosome": "Y", "start_pos": 16786986, "end_pos": 16783304, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145851.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145851.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107506.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107506.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT08", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT08" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT08", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT08" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT08", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT08" } ], "pmid": "" }, { "name": "negative regulation of cell differentiation", "id": "GO:0045596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045596", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT08", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT08" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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} ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NT12-1", "uniprot_ac": "A0ABI0NT12", "uniprot_id": "A0ABI0NT12_BOVIN", "mass": { "chemical_mass": 26413.0, "monoisotopic_mass": 26413.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Shadow of prion protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NT12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT12/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT12", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT12#function" }, { "database": "UniProtKB", "id": "ARBA00025683", "url": "https://www.uniprot.org/uniprotkb/ARBA00025683#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT12", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT12" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT12", "locus": {} } ], "crossref": [ { "id": "IPR029238", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029238", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR28552", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28552", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28552:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28552:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14999", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14999", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NT12", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT12-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRWSGGCEVLKPVGLTGIGGPVRVGVRKGWRTGRRVGGCWAEGGCACEGPPLSPPSRPGDEPPRLPAPRQGRRPHAHPRSARRRRPGLRHSPPSARAAVLGAAAVLPEARGWFCSRNMNWAAAVCWALLLAATFLCDGSAAKGGRGGARGSARGGRGAARVRVRPAPRYAGSSMRVAAGAAAGAAAGAAAGLAAGSSWRRAAGPAELGPEDAEDGAPGSNGTGRGVYSYWAWTSGTGPTGHRHLCPLLGGALGALRLLRP", "length": 260, "header": "tr|A0ABI0NT12-1|A0ABI0NT12_BOVIN Isoform 1 of Shadow of prion protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NT12-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NT12-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT12/entry#A0ABI0NT12-1", "sequence": { "sequence": "MRWSGGCEVLKPVGLTGIGGPVRVGVRKGWRTGRRVGGCWAEGGCACEGPPLSPPSRPGDEPPRLPAPRQGRRPHAHPRSARRRRPGLRHSPPSARAAVLGAAAVLPEARGWFCSRNMNWAAAVCWALLLAATFLCDGSAAKGGRGGARGSARGGRGAARVRVRPAPRYAGSSMRVAAGAAAGAAAGAAAGLAAGSSWRRAAGPAELGPEDAEDGAPGSNGTGRGVYSYWAWTSGTGPTGHRHLCPLLGGALGALRLLRP", "length": 260, "header": "tr|A0ABI0NT12-1|A0ABI0NT12_BOVIN Isoform 1 of Shadow of prion protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NT12-1" }, "locus": { "chromosome": "26", "start_pos": 25585451, "end_pos": 25583946, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138702.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138702.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107444.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107444.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT12", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT12" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT12", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 220, "end_pos": 222 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NT31-1", "uniprot_ac": "A0ABI0NT31", "uniprot_id": "A0ABI0NT31_BOVIN", "mass": { "chemical_mass": 34567.0, "monoisotopic_mass": 34567.0 }, "refseq": { "ac": "NP_001377348", "name": "olfactory receptor family 2 subfamily H member 20", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377348" }, "gene_names": [ { "name": "OR2H20", "type": "recommended", "evidence": [ { "id": "A0ABI0NT31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT31" } ] }, { "name": "OR2H20", "type": "synonym", "evidence": [ { "id": "NP_001377348", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377348" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NT31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT31/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 2 subfamily H member 20", "type": "synonym", "evidence": [ { "id": "NP_001377348", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377348" } ] }, { "name": "olfactory receptor, family 2, subfamily H, member 2-like", "type": "synonym", "evidence": [ { "id": "NP_001377348", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377348" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377348", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377348" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT31", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT31#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT31", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT31" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2H20", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT31", "locus": {} } ], "crossref": [ { "id": "cd15947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "785162", "url": "https://www.ncbi.nlm.nih.gov/gene/785162", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377514", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377514" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTG0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTG0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTG0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTG0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4D1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTG0", "locus": {} } ], "crossref": [ { "id": "cd15936", "url": 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"annotation": "Ubiquitin-like protein that plays a role in cell proliferation and sister chromatid cohesion by associating with spliceosomal proteins. Participates thereby in pre-mRNA splicing by maintaining spliceosome integrity. Promotes the functional integrity of the Fanconi anemia DNA repair pathway by interacting with FANCI component and subsequently mediating the formation of FANCI homodimers. 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[ "Protein" ] } ], "sequence": { "sequence": "MPALRPLRLLLLLAGLTAGASLPPGPGGHPGVCPNQLSPNLWVDAQSTCERECVGDQDCAATEKCCTNVCGLQSCVAARFPDGGPAASRLAASCEGFVCAQQGSDCDIWDGQPVCRCRDRCEKEPSFTCASDGLTYYNRCYMDAEACLRGLRLRVVPCKHVLSWPPSSPRPPETTARPTPGDAPVPPALYSSPSPQAVYVGGTASLHCDVSGRPPPAVTWEKQSDQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQRDPAGAGAHEAANAPAQCLPSTQACVGPPSGRVLWHFDPQRRGCMTFPVGSCAGGAQGFETYEACQQACARDPGDACALPAVQGPCQGWEPRWAYSPLLQHCHPFEYSGCEGNGNNFESRESCEHACPVPRTPPCRACRLRSKLALSLCRSDFAIVGRLTEVLEEPEAGGGGIARVALDEVLKDDKMGLRLLGTKYLEVTLIGVDRACPCPNVTAGDGPLVIMGEVRDGVAMLDAGSYVRAASEKRVKKISELLERKACELLNRFQD", "length": 550, "header": "tr|A0ABI0NTR7-1|A0ABI0NTR7_BOVIN Isoform 1 of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 OS=Bos taurus OX=9913 GN=WFIKKN1 PE=3 SV=1 CANONICAL=A0ABI0NTR7-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NTR7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTR7/entry#A0ABI0NTR7-1", "sequence": { "sequence": "MPALRPLRLLLLLAGLTAGASLPPGPGGHPGVCPNQLSPNLWVDAQSTCERECVGDQDCAATEKCCTNVCGLQSCVAARFPDGGPAASRLAASCEGFVCAQQGSDCDIWDGQPVCRCRDRCEKEPSFTCASDGLTYYNRCYMDAEACLRGLRLRVVPCKHVLSWPPSSPRPPETTARPTPGDAPVPPALYSSPSPQAVYVGGTASLHCDVSGRPPPAVTWEKQSDQRENLIMRPDQMYGNVVVTSIGQLVLYNARPEDAGLYTCTARNAAGLLRADFPLSVVQRDPAGAGAHEAANAPAQCLPSTQACVGPPSGRVLWHFDPQRRGCMTFPVGSCAGGAQGFETYEACQQACARDPGDACALPAVQGPCQGWEPRWAYSPLLQHCHPFEYSGCEGNGNNFESRESCEHACPVPRTPPCRACRLRSKLALSLCRSDFAIVGRLTEVLEEPEAGGGGIARVALDEVLKDDKMGLRLLGTKYLEVTLIGVDRACPCPNVTAGDGPLVIMGEVRDGVAMLDAGSYVRAASEKRVKKISELLERKACELLNRFQD", "length": 550, "header": "tr|A0ABI0NTR7-1|A0ABI0NTR7_BOVIN Isoform 1 of WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 OS=Bos taurus OX=9913 GN=WFIKKN1 PE=3 SV=1 CANONICAL=A0ABI0NTR7-1" }, "locus": { "chromosome": "25", "start_pos": 543677, "end_pos": 541147, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148712.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148712.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104268.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104268.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 179, "start_aa": "Thr", "end_pos": 179, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr179", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 203, "start_aa": "Thr", "end_pos": 203, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr203", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:540233", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540233", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTR7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTR7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTR7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NTR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTR7" }, { "id": "PS50279", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50279" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BPTI/Kunitz inhibitor", "eco_id": "ECO_0000259", "start_pos": 308, "end_pos": 352, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NTR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTR7" }, { "id": "PS50835", "database": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377203", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377203" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTY1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTY1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTY1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTY1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR7E199", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTY1", "locus": {} } ], "crossref": [ { "id": "cd15234", "url": 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{ "uniprot_canonical_ac": "A0ABI0NXZ3-1", "uniprot_ac": "A0ABI0NXZ3", "uniprot_id": "A0ABI0NXZ3_BOVIN", "mass": { "chemical_mass": 56115.0, "monoisotopic_mass": 56115.0 }, "refseq": { "ac": "XP_024840127", "name": "CUGBP Elav-like family member 4 isoform X46", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840127" }, "gene_names": [ { "name": "CELF4", "type": "recommended", "evidence": [ { "id": "A0ABI0NXZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3" } ] }, { "name": "BRUNOL4", "type": "synonym", "evidence": [ { "id": "XP_024840127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840127" } ] }, { "name": "CELF4", "type": "synonym", "evidence": [ { "id": "XP_024840127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840127" } ] } ], "protein_names": [ { "name": "CUGBP Elav-like family member 4 isoform X46", "type": "synonym", "evidence": [ { "id": "XP_024840127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840127" } ] }, { "name": "CUGBP Elav-like family member 4", "type": "synonym", "evidence": [ { "id": "A0ABI0NXZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.", "evidence": [ { "database": "UniProtKB", "id": "A0AAF6DLK3", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLK3#function" }, { "database": "UniProtKB", "id": "ARBA00058875", "url": "https://www.uniprot.org/uniprotkb/ARBA00058875#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CELF4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3", "locus": { "chromosome": "24", "start_pos": 19817206, "end_pos": 19505652, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004940", "url": "https://www.ensembl.org/id/ENSBTAG00000004940" } ] } } ], "crossref": [ { "id": "ENSBTAG00000004940", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004940", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12632", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12632", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12635", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12635", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "535177", "url": "https://www.ncbi.nlm.nih.gov/gene/535177", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N578", "url": "https://www.orthodb.org/?gene=A0A3Q1N578", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024840127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840127", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1N578", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N578", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N578-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N578-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLK3", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYIKMATLANGQADNASLSTSGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFGRPPVPSRCQAPSCQGGQCPINSSARRLRELRQPGQRADRHPGHERLPDRHEEAQGAAEAAQRRQSPVLSAGGSVPRGRPGLAQGRMLNGLH", "length": 526, "header": "tr|A0ABI0NXZ3-1|A0ABI0NXZ3_BOVIN Isoform 1 of CUGBP Elav-like family member 4 OS=Bos taurus OX=9913 GN=CELF4 PE=3 SV=1 CANONICAL=A0ABI0NXZ3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N578-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3/entry#A0A3Q1N578-1", "sequence": { "sequence": "MYIKMATLANGQADNASLSTSGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY", "length": 448, "header": "tr|A0A3Q1N578-1|A0ABI0NXZ3_BOVIN Computationally mapped isoform of CUGBP Elav-like family member 4 OS=Bos taurus OX=9913 GN=CELF4 PE=3 SV=2 CANONICAL=A0ABI0NXZ3-1" }, "locus": { "chromosome": "24", "start_pos": 19807769, "end_pos": 19505751, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085635.3", "url": "https://www.ensembl.org/id/ENSBTAT00000085635.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065241.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065241.2" } ] } }, { "isoform_ac": "A0AAF6DLK3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3/entry#A0AAF6DLK3-1", "sequence": { "sequence": "MYIKMATLANGQADNASLSTSGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY", "length": 486, "header": "tr|A0AAF6DLK3-1|A0ABI0NXZ3_BOVIN Computationally mapped isoform of CUGBP Elav-like family member 4 OS=Bos taurus OX=9913 GN=CELF4 PE=3 SV=1 CANONICAL=A0ABI0NXZ3-1" }, "locus": { "chromosome": "24", "start_pos": 19807769, "end_pos": 19505751, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006498.8", "url": "https://www.ensembl.org/id/ENSBTAT00000006498.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006498.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006498.6" } ] } }, { "isoform_ac": "A0ABI0NXZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3/entry#A0ABI0NXZ3-1", "sequence": { "sequence": "MYIKMATLANGQADNASLSTSGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFGRPPVPSRCQAPSCQGGQCPINSSARRLRELRQPGQRADRHPGHERLPDRHEEAQGAAEAAQRRQSPVLSAGGSVPRGRPGLAQGRMLNGLH", "length": 526, "header": "tr|A0ABI0NXZ3-1|A0ABI0NXZ3_BOVIN Isoform 1 of CUGBP Elav-like family member 4 OS=Bos taurus OX=9913 GN=CELF4 PE=3 SV=1 CANONICAL=A0ABI0NXZ3-1" }, "locus": { "chromosome": "24", "start_pos": 19816632, "end_pos": 19505751, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151145.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151145.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106221.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106221.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NXZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ3" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 135, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 15, "end_pos": 17 }, { "start_pos": 456, "end_pos": 458 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NVY9-1", "uniprot_ac": "A0ABI0NVY9", "uniprot_id": "A0ABI0NVY9_BOVIN", "mass": { "chemical_mass": 67000.0, "monoisotopic_mass": 67000.0 }, "refseq": {}, "gene_names": [ { "name": "PPP2R5C", "type": "recommended", "evidence": [ { "id": "A0ABI0NVY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit", "type": "recommended", "evidence": [ { "id": "A0ABI0NVY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1NIB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NIB3#function" }, { "database": "UniProtKB", "id": "PIRNR028043", "url": "https://www.uniprot.org/uniprotkb/PIRNR028043#function" }, { "database": "UniProtKB", "id": "A0A3Q1LPJ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPJ3#function" }, { "database": "UniProtKB", "id": "A0A3Q1LY55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LY55#function" }, { "database": "UniProtKB", "id": "A0ABI0NVY9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9#function" }, { "database": "UniProtKB", "id": "A0ABI0P5U3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5U3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVY9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PPP2R5C", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9", "locus": { "chromosome": "21", "start_pos": 66817662, "end_pos": 66720912, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020192", "url": "https://www.ensembl.org/id/ENSBTAG00000020192" } ] } } ], "crossref": [ { "id": "ENSBTAG00000020192", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020192", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "505757", "url": "https://www.ncbi.nlm.nih.gov/gene/505757", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002554", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002554", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPJ3", "url": "https://www.orthodb.org/?gene=A0A3Q1LPJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LY55", "url": "https://www.orthodb.org/?gene=A0A3Q1LY55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NIB3", "url": "https://www.orthodb.org/?gene=A0A3Q1NIB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10257", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10257", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10257:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10257:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01603", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01603", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LPJ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LY55", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LY55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LY55-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LY55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NIB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NIB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NIB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NIB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRG5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRG5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVY9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVY9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5U3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5U3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5U3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5U3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPNKNKKEKESPKAGKSGKSSKEGQDIIDSEQIPSRKNSLIAAPSAASSKIKVPAPQPIVKRDRRQNSSRLSASNNRELQKLPSLKDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRLLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYSQASTISIPVAMETDGPLFEDVQMLRKTVNEEARQAQKDPKKERPLARRKSELPQDLHTKSALEAHGRAEEPAPQDGR", "length": 579, "header": "tr|A0ABI0NVY9-1|A0ABI0NVY9_BOVIN Isoform 1 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Bos taurus OX=9913 GN=PPP2R5C PE=3 SV=1 CANONICAL=A0ABI0NVY9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9/entry#A0A3Q1LPJ3-1", "sequence": { "sequence": "MLTCNKAGSRMVVDAASSNGPFQPVALLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRLLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYSQASTISIPVAMETDGPLFEDVQMLRKTVNEEARQSVGRKAVSSVQLRKV", "length": 496, "header": "tr|A0A3Q1LPJ3-1|A0ABI0NVY9_BOVIN Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Bos taurus OX=9913 GN=PPP2R5C PE=3 SV=2 CANONICAL=A0ABI0NVY9-1" }, "locus": { "chromosome": "21", "start_pos": 66812911, "end_pos": 66720931, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069352.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069352.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061999.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061999.2" } ] } }, { "isoform_ac": "A0A3Q1LY55-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9/entry#A0A3Q1LY55-1", "sequence": { "sequence": "MLTCNKAGSRMVVDAASSNGPFQPVALLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRLLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYSQASTISIPVAMETDGPLFEDVQMLRKTVNEEARQAQKDPKKERPLARRKSELPQDLHTKSALEAHGRAEEPAPQDGR", "length": 506, "header": "tr|A0A3Q1LY55-1|A0ABI0NVY9_BOVIN Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Bos taurus OX=9913 GN=PPP2R5C PE=3 SV=2 CANONICAL=A0ABI0NVY9-1" }, "locus": { "chromosome": "21", "start_pos": 66815339, "end_pos": 66720931, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073128.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073128.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060545.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060545.2" } ] } }, { "isoform_ac": "A0A3Q1NIB3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9/entry#A0A3Q1NIB3-1", "sequence": { "sequence": "MLTCNKAGSRMVVDAASSNGPFQPVALLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRLLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYSQASTISIPVAMETDGPLFEDVQMLRKTVNEEARQLVMVKTKASGPSGDSDESCP", "length": 501, "header": "tr|A0A3Q1NIB3-1|A0ABI0NVY9_BOVIN Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Bos taurus OX=9913 GN=PPP2R5C PE=3 SV=2 CANONICAL=A0ABI0NVY9-1" }, "locus": { "chromosome": "21", "start_pos": 66813115, "end_pos": 66720931, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072379.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072379.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071753.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071753.2" } ] } }, { "isoform_ac": "A0AAA9TRG5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9/entry#A0AAA9TRG5-1", "sequence": { "sequence": "MPNKNKKEKESPKAGKSGKSSKEGQDIIDSEHYCLRAGATELEITTENAEMLGPSLLPPQDPRGNMAY", "length": 68, "header": "tr|A0AAA9TRG5-1|A0ABI0NVY9_BOVIN Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Bos taurus OX=9913 GN=PPP2R5C PE=3 SV=1 CANONICAL=A0ABI0NVY9-1" }, "locus": { "chromosome": "21", "start_pos": 66681602, "end_pos": 66678651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123173.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123173.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099611.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099611.1" } ] } }, { "isoform_ac": "A0ABI0NVY9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9/entry#A0ABI0NVY9-1", "sequence": { "sequence": "MPNKNKKEKESPKAGKSGKSSKEGQDIIDSEQIPSRKNSLIAAPSAASSKIKVPAPQPIVKRDRRQNSSRLSASNNRELQKLPSLKDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRLLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYSQASTISIPVAMETDGPLFEDVQMLRKTVNEEARQAQKDPKKERPLARRKSELPQDLHTKSALEAHGRAEEPAPQDGR", "length": 579, "header": "tr|A0ABI0NVY9-1|A0ABI0NVY9_BOVIN Isoform 1 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Bos taurus OX=9913 GN=PPP2R5C PE=3 SV=1 CANONICAL=A0ABI0NVY9-1" }, "locus": { "chromosome": "21", "start_pos": 66815339, "end_pos": 66678651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153813.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153813.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105046.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105046.1" } ] } }, { "isoform_ac": "A0ABI0P5U3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9/entry#A0ABI0P5U3-1", "sequence": { "sequence": "MLTCNKAGSRMVVDAASSNGPFQPVALLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRLLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQAQKDPKKERPLARRKSELPQDLHTKSALEAHGRAEEPAPQDGR", "length": 485, "header": "tr|A0ABI0P5U3-1|A0ABI0P5U3_BOVIN Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Bos taurus OX=9913 GN=PPP2R5C PE=3 SV=1 CANONICAL=A0ABI0NVY9-1" }, "locus": { "chromosome": "21", "start_pos": 66815339, "end_pos": 66720931, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150449.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150449.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107182.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107182.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVY9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9" } ], "pmid": "" }, { "name": "protein phosphatase type 2A complex", "id": "GO:0000159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000159", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVY9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVY9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVY9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11973", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11973", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505852", "url": "https://www.ncbi.nlm.nih.gov/gene/505852", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505852", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505852", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LJ25", "url": "https://www.orthodb.org/?gene=A0A3Q1LJ25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MAZ5", "url": "https://www.orthodb.org/?gene=F1MAZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47544", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47544", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47544:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47544:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9958810", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958810", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LJ25", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJ25-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T929", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T929", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T929-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T929-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNQ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ02", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ02-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6B6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6B6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6B6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MAZ5", "url": "https://www.uniprot.org/uniprotkb/F1MAZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MAZ5-1", "url": "https://www.uniprot.org/uniprotkb/F1MAZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDKNLKVFLSDKFVVSEKEEVRKEETPEPSAHLPGHGDIEGQQLPSSPAEPEEQEWSQKTDHSDCETLSHQSESPSDTKTDPFESASDTESLPGDLLEGICLPSRGTSGDREAHKGCSDTPASGNPQEQYLTDVPGLDPKEELDLCLDFKEESHETGLRTFATVAGEVRAILQEDVAGPELELPPGRAALLTQDCARGLTGSYGLPPAKVVTVQDITGSSVFSSQKSRSESHLGTPLVWPLLLWCTEQSQSWPNIHNRQRGCQLSPRSPLNSTAPLGARAGKKCPPDPTSKTGLLCSQYSFDTTCWLPLGTSCLLHAKFYHSVPENSYDEGRALPRHCRWLTRTLNRAHSIAEFPLRNSEDPLGQNFVKFGTHLKEGTEAERAPITQTPLHPVPTQLSHLLPTSQRKTLPLKDQYKLRALNWKRASQDTPSEGLWLENQLGQDSRSCPVSSCLTAELVSLTTEEVPVPAKCKSGHGPESRPGEPQGPGQAPDAEDVSDAQKHLQDISAEPGNQTSNYTSKYILSEKRKPSARAKFPNHPSKSGSLVWNRDWGVCSRVIDNSYAPETTLKSSTADTLKKAEDVMVPDPSVTKNALQGFSGVAGATMSHCSCGDEECEQGHKGDTISFAEGLQTEPKADTSSRGTLIIIAVEQKGLQATRKKMGPLLRTQSCEFLEERPGSPHSAGATPCESPLAGKPKTCGNECELPAACSLRGNDGALRQVAQASESGIVLIPQAASEDWPPGRRKTSQEHAGDMLSTGVPMEENQPEASQSSRIPAAREEATRKPEACGPHPSGSRGPPSPEDTRRVCAAEGDADTDKQPGAQARARKSALQQPRPPHQLRQASREPGKRLAFPKVISFRKGKPLAAESPGGGHPGDSSGLKELCSDRQPPTGSAQSASGQAGTPCNAHASTLPVIGLQGLSQGAPGLMEVGRVDTPGDLGSRRQSSESCDAKRLKTPEKRLRARLASAHKTFASFFESRVLEKENTGQCSSCSLKDQKEKSRLRQSSWRTFLKSKDAQGSKRPSLVSLIPGPEILNTPSRFPPETNSHCEKQAEHKESYVFRDHWTPTHSPIPLSSGNLSSSDNRRKSEPTIKCTSTQESGEYIAPSTFPEKSWPMSPTSPGSQQAGISHTLPSSSTCCLAQGSQSVPSKPLSPKPQSLRPGAQGADFHYPEKGRAISVVSLGSYSHVDNSSEAPGNPKMSQAWISLLLSLQALDQGEQKEESGKRGQHPCGVSTAPSLKDLLGSESHMLWEEQPGKKPSCFQDLKAFHTEPAPGPFSTAEVGTWILPFISAEDVPRETPSQPRRIPQHSCISLDDLWLEKTQRRKLKKQAQFERKTHAHKDGVQCWRKMIITSPKSLNLPGRSHPFSQSAPTGLNHMGWPEPTPDIALPDGALDTALRGDEAGSEEDLYEDVHSSSHHYSHTGGGGEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPANFVRLRVNQDEPADDEALGPGHQGTGDGGGTEAQGSRDQMRTNVINEILSTERDYIKHLRDICEGYLRQCRKRADMFSEEQLRIIFGNIEDIYRCQKAFVKALEQKFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACMELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIHSGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRVDMDSLQVVDLEDGKDRELHVSVRNAFRLCCGPSGESHLLCAKKPEQKQRWLKAFAREREQVRLDQETGFSITQLQRKQAMLNASKQQAMGKPKALGRPYYLARQKHPALPTSLPQQQVLVLAEPKRKPSTFWHSISRLAPFRK", "length": 1939, "header": "tr|A0ABI0NZ02-1|A0ABI0NZ02_BOVIN Isoform 1 of Rho guanine nucleotide exchange factor 4 OS=Bos taurus OX=9913 GN=ARHGEF4 PE=4 SV=1 CANONICAL=A0ABI0NZ02-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJ25-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ02/entry#A0A3Q1LJ25-1", "sequence": { "sequence": "MLSVVHFLRSLFKTPEPSAHLPGHGDIEGQQLPSSPAEPEEQEWSQKTDHSDCETLSHQSESPSDTKTDPFESASDTESLPGDLLEGICLPSRGTSGDREAHKGCSDTPASGNPQEQYLTDVPGLDPKEELDLCLDFKEESHETGLRTFATVAGEVRAILQEDVAGPELELPPGRAALLTQDCARGLTGSYGLPPAKVVTVQDITGSSVFSSQKSRSESHLGTPLVWPLLLWCTEQSQSWPNIHNRQRGCQLSPRSPLNSTAPLGARAGKKCPPDPTSKTGLLCSQYSFDTTCWLPLGTSCLLHAKFYHSVPENSYDEGRALPRHCRWLTRTLNRAHSIAEFPLRNSEDPLGQNFVKFGTHLKEGTEAERAPITQTPLHPVPTQLSHLLPTSQRKTLPLKDQYKLRALNWKRASQDTPSEGLWLENQLGQDSRSCPVSSCLTAELVSLTTEEVPVPAKCKSGHGPESRPGEPQGPGQAPDAEDVSDAQKHLQDISAEPGNQTSNYTSKYILSEKRKPSARAKFPNHPSKSGSLVWNRDWGVCSRVIDNSYAPETTLKSSTADTLKKAEDVMVPDPSVTKNALQGFSGVAGATMSHCSCGDEECEQGHKGDTISFAEGLQTEPKADTSSRGTLIIIAVEQKGLQATRKKMGPLLRTQSCEFLEERPGSPHSAGATPCESPLAGKPKTCGNECELPAACSLRGNDGALRQVAQASESGIVLIPQAASEDWPPGRRKTSQEHAGDMLSTGVPMEENQPEASQSSRIPAAREEATRKPEACGPHPSGSRGPPSPEDTRRVCAAEGDADTDKQPGAQARARKSALQQPRPPHQLRQASREPGKRLAFPKVISFRKGKPLAAESPGGGHPGDSSGLKELCSDRQPPTGSAQSASGQAGTPCNAHASTLPVIGLQGLSQGAPGLMEVGRVDTPGDLGSRRQSSESCDAKRLKTPEKRLRARLASAHKTFASFFESRVLEKENTGQCSSCSLKDQKEKSRLRQSSWRTFLKSKDAQGSKRPSLVSLIPGPEILNTPSRFPPETNSHCEKQAEHKESYVFRDHWTPTHSPIPLSSGNLSSSDNRRKSEPTIKCTSTQESGEYIAPSTFPEKSWPMSPTSPGSQQAGISHTLPSSSTCCLAQGSQSVPSKPLSPKPQSLRPGAQGADFHYPEKGRAISVVSLGSYSHVDNSSEAPGNPKMSQAWISLLLSLQALDQGEQKEESGKRGQHPCGVSTAPSLKDLLGSESHMLWEEQPGKKPSCFQDLKAFHTEPAPGPFSTAEVGTWILPFISAEDVPRETPSQPRRIPQHSCISLDDLWLEKTQRRKLKKQAQFERKTHAHKDGVQCWRKMIITSPKSLNLPGRSHPFSQSAPTGLNHMGWPEPTPDIALPDGALDTALRGDEAGSEEDLYEDVHSSSHHYSHTGGGGEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPANFVRLRVNQDEPADDEALGPGHQGTGDGGGTEAQGSRDQMRTNVINEILSTERDYIKHLRDICEGYLRQCRKRADMFSEEQLRIIFGNIEDIYRCQKAFVKALEQKFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACMELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIHSGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRVDMDSLQVVDLEDGKDRELHVSVRNAFRLCCGPSGESHLLCAKKPEQKQRWLKAFAREREQVRLDQETGFSITQLQRKQAMLNASKQQAMGKPKALGRPYYLARQKHPALPTSLPQQQVLVLAEPKRKPSTFWHSISRLAPFRK", "length": 1926, "header": "tr|A0A3Q1LJ25-1|A0ABI0NZ02_BOVIN Computationally mapped isoform of Rho guanine nucleotide exchange factor 4 OS=Bos taurus OX=9913 GN=ARHGEF4 PE=4 SV=2 CANONICAL=A0ABI0NZ02-1" }, "locus": { "chromosome": "2", "start_pos": 1863820, "end_pos": 1533388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086719.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086719.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059272.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059272.2" } ] } }, { "isoform_ac": "A0AAA9T929-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ02/entry#A0AAA9T929-1", "sequence": { "sequence": "MLSVVHFLRSLFKTPEPSAHLPGHGDIEGQQLPSSPAEPEEQEWSQKTDHSDCETLSHQSESPSDTKTDPFESASDTESLPGDLLEGICLPSRGTSGDREAHKGCSDTPASGNPQEQYLTDVPGLDPKEELDLCLDFKEESHETGLRTFATVAGEVRAILQEDVAGPELELPPGRAALLTQDCARGLTGSYGLPPAKVVTVQDITGSSVFSSQKSRSESHLGTPLVWPLLLWCTEQSQSWPNIHNRQRGCQLSPRSPLNSTAPLGARAGKKCPPDPTSKTGLLCSQYSFDTTCWLPLGTSCLLHAKFYHSVPENSYDEGRALPRHCRWLTRTLNRAHSIAEFPLRNSEDPLGQNFVKFGTHLKEGTEAERAPITQTPLHPVPTQLSHLLPTSQRKTLPLKDQYKLRALNWKRASQDTPSEGLWLENQLGQDSRSCPVSSCLTAELVSLTTEEVPVPAKCKSGHGPESRPGEPQGPGQAPDAEDVSDAQKHLQDISAEPGNQTSNYTSKYILSEKRKPSARAKFPNHPSKSGSLVWNRDWGVCSRVIDNSYAPETTLKSSTADTLKKAEDVMVPDPSVTKNALQGFSGVAGATMSHCSCGDEECEQGHKGDTISFAEGLQTEPKADTSSRGTLIIIAVEQKGLQATRKKMGPLLRTQSCEFLEERPGSPHSAGATPCESPLAGKPKTCGNECELPAACSLRGNDGALRQVAQASESGIVLIPQAASEDWPPGRRKTSQEHAGDMLSTGVPMEENQPEASQSSRIPAAREEATRKPEACGPHPSGSRGPPSPEDTRRVCAAEGDADTDKQPGAQARARKSALQQPRPPHQLRQASREPGKRLAFPKVISFRKGKPLAAESPGGGHPGDSSGLKELCSDRQPPTGSAQSASGQAGTPCNAHASTLPVIGLQGLSQGAPGLMEVGRVDTPGDLGSRRQSSESCDAKRLKTPEKRLRARLASAHKTFASFFESRVLEKENTGQCSSCSLKDQKEKSRLRQSSWRTFLKSKDAQGSKRPSLVSLIPGPEILNTPSRFPPETNSHCEKQAEHKESYVFRDHWTPTHSPIPLSSGNLSSSDNRRKSEPTIKCTSTQESGEYIAPSTFPEKSWPMSPTSPGSQQAGISHTLPSSSTCCLAQGSQSVPSKPLSPKPQSLRPGAQGADFHYPEKGRAISVVSLGSYSHVDNSSEAPGNPKMSQAWISLLLSLQALDQGEQKEESGKRGQHPCGVSTAPSLKDLLGSESHMLWEEQPGKKPSCFQDLKAFHTEPAPGPFSTAEVGTWILPFISAEDVPRETPSQPRRIPQHSCISLDDLWLEKTQRRKLKKQAQFERKTHAHKDGVQCWRKMIITSPKSLNLPGRSHPFSQSAPTGLNHMGWPEPTPDIALPDGALDTALRGDEAGSEEDLYEDVHSSSHHYSHTGGGGEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPANFVRLRVNQDEPADDEALGPGHQGTGDGGGTEAQGSRDQMRTNVINEILSTERDYIKHLRDICEQADFQIYSEYCNNHPNACMELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIHSGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRVDMDSLQVVDLEDGKDRELHVSVRNAFRLCCGPSGESHLLCAKKPEQKQRWLKAFAREREQVRLDQETGFSITQLQRKQAMLNASKQQAMGKPKALGRPYYLARQKHPALPTSLPQQQVLVLAEPKRKPSTFWHSISRLAPFRK", "length": 1866, "header": "tr|A0AAA9T929-1|A0ABI0NZ02_BOVIN Computationally mapped isoform of Rho guanine nucleotide exchange factor 4 OS=Bos taurus OX=9913 GN=ARHGEF4 PE=4 SV=1 CANONICAL=A0ABI0NZ02-1" }, "locus": { "chromosome": "2", "start_pos": 1863820, "end_pos": 1533388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129251.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129251.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092400.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092400.1" } ] } }, { "isoform_ac": "A0AAA9TNQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ02/entry#A0AAA9TNQ5-1", "sequence": { "sequence": "MLSVVHFLRSLFKTPEPSAHLPGHGDIEGQQLPSSPAEPEEQEWSQKTDHSDCETLSHQSESPSDTKTDPFESASDTESLPGDLLEGICLPSRGTSGDREAHKGCSDTPASGNPQEQYLTDVPGLDPKEELDLCLDFKEESHETGLRTFATVAGEVRAILQEDVAGPELELPPGRAALLTQDCARGLTGSYGLPPAKVVTVQDITGSSVFSSQKSRSESHLGTPLVWPLLLWCTEQSQSWPNIHNRQRGCQLSPRSPLNSTAPLGARAGKKCPPDPTSKTGLLCSQYSFDTTCWLPLGTSCLLHAKFYHSVPENSYDEGRALPRHCRWLTRTLNRAHSIAEFPLRNSEDPLGQNFVKFGTHLKEGTEAERAPITQTPLHPVPTQLSHLLPTSQRKTLPLKDQYKLRALNWKRASQDTPSEGLWLENQLGQDSRSCPVSSCLTAELVSLTTEEVPVPAKCKSGHGPESRPGEPQGPGQAPDAEDVSDAQKHLQDISAEPGNQTSNYTSKYILSEKRKPSARAKFPNHPSKSGSLVWNRDWGVCSRVIDNSYAPETTLKSSTADTLKKAEDVMVPDPSVTKNALQGFSGVAGATMSHCSCGDEECEQGHKGDTISFAEGLQTEPKADTSSRGTLIIIAVEQKGLQATRKKMGPLLRTQSCEFLEERPGSPHSAGATPCESPLAGKPKTCGNECELPAACSLRGNDGALRQVAQASESGIVLIPQAASEDWPPGRRKTSQEHAGDMLSTGVPMEENQPEASQSSRIPAAREEATRKPEACGPHPSGSRGPPSPEDTRRVCAAEGDADTDKQPGAQARARKSALQQPRPPHQLRQASREPGKRLAFPKVISFRKGKPLAAESPGGGHPGDSSGLKELCSDRQPPTGSAQSASGQAGTPCNAHASTLPVIGLQGLSQGAPGLMEVGRVDTPGDLGSRRQSSESCDAKRLKTPEKRLRARLASAHKTFASFFESRVLEKENTGQCSSCSLKDQKEKSRLRQSSWRTFLKSKDAQGSKRPSLVSLIPGPEILNTPSRFPPETNSHCEKQAEHKESYVFRDHWTPTHSPIPLSSGNLSSSDNRRKSEPTIKCTSTQESGEYIAPSTFPEKSWPMSPTSPGSQQAGISHTLPSSSTCCLAQGSQSVPSKPLSPKPQSLRPGAQGADFHYPEKGRAISVVSLGSYSHVDNSSEAPGNPKMSQAWISLLLSLQALDQGEQKEESGKRGQHPCGVSTAPSLKDLLGSESHMLWEEQPGKKPSCFQDLKAFHTEPAPGPFSTAEVGTWILPFISAEDVPRETPSQPRRIPQHSCISLDDLWLEKTQRRKLKKQAQFERKTHAHKDGVQCWRKMIITSPKSLNLPGRSHPFSQSAPTGLNHMGWPEPTPDIALGRPYYLARQKHPALPTSLPQQQVLVLAEPKRKPSTFWHSISRLAPFRK", "length": 1427, "header": "tr|A0AAA9TNQ5-1|A0ABI0NZ02_BOVIN Computationally mapped isoform of Rho guanine nucleotide exchange factor 4 OS=Bos taurus OX=9913 GN=ARHGEF4 PE=4 SV=1 CANONICAL=A0ABI0NZ02-1" }, "locus": { "chromosome": "2", "start_pos": 1863820, "end_pos": 1533388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117469.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117469.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098676.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098676.1" } ] } }, { "isoform_ac": "A0ABI0NZ02-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ02/entry#A0ABI0NZ02-1", "sequence": { "sequence": "MGDKNLKVFLSDKFVVSEKEEVRKEETPEPSAHLPGHGDIEGQQLPSSPAEPEEQEWSQKTDHSDCETLSHQSESPSDTKTDPFESASDTESLPGDLLEGICLPSRGTSGDREAHKGCSDTPASGNPQEQYLTDVPGLDPKEELDLCLDFKEESHETGLRTFATVAGEVRAILQEDVAGPELELPPGRAALLTQDCARGLTGSYGLPPAKVVTVQDITGSSVFSSQKSRSESHLGTPLVWPLLLWCTEQSQSWPNIHNRQRGCQLSPRSPLNSTAPLGARAGKKCPPDPTSKTGLLCSQYSFDTTCWLPLGTSCLLHAKFYHSVPENSYDEGRALPRHCRWLTRTLNRAHSIAEFPLRNSEDPLGQNFVKFGTHLKEGTEAERAPITQTPLHPVPTQLSHLLPTSQRKTLPLKDQYKLRALNWKRASQDTPSEGLWLENQLGQDSRSCPVSSCLTAELVSLTTEEVPVPAKCKSGHGPESRPGEPQGPGQAPDAEDVSDAQKHLQDISAEPGNQTSNYTSKYILSEKRKPSARAKFPNHPSKSGSLVWNRDWGVCSRVIDNSYAPETTLKSSTADTLKKAEDVMVPDPSVTKNALQGFSGVAGATMSHCSCGDEECEQGHKGDTISFAEGLQTEPKADTSSRGTLIIIAVEQKGLQATRKKMGPLLRTQSCEFLEERPGSPHSAGATPCESPLAGKPKTCGNECELPAACSLRGNDGALRQVAQASESGIVLIPQAASEDWPPGRRKTSQEHAGDMLSTGVPMEENQPEASQSSRIPAAREEATRKPEACGPHPSGSRGPPSPEDTRRVCAAEGDADTDKQPGAQARARKSALQQPRPPHQLRQASREPGKRLAFPKVISFRKGKPLAAESPGGGHPGDSSGLKELCSDRQPPTGSAQSASGQAGTPCNAHASTLPVIGLQGLSQGAPGLMEVGRVDTPGDLGSRRQSSESCDAKRLKTPEKRLRARLASAHKTFASFFESRVLEKENTGQCSSCSLKDQKEKSRLRQSSWRTFLKSKDAQGSKRPSLVSLIPGPEILNTPSRFPPETNSHCEKQAEHKESYVFRDHWTPTHSPIPLSSGNLSSSDNRRKSEPTIKCTSTQESGEYIAPSTFPEKSWPMSPTSPGSQQAGISHTLPSSSTCCLAQGSQSVPSKPLSPKPQSLRPGAQGADFHYPEKGRAISVVSLGSYSHVDNSSEAPGNPKMSQAWISLLLSLQALDQGEQKEESGKRGQHPCGVSTAPSLKDLLGSESHMLWEEQPGKKPSCFQDLKAFHTEPAPGPFSTAEVGTWILPFISAEDVPRETPSQPRRIPQHSCISLDDLWLEKTQRRKLKKQAQFERKTHAHKDGVQCWRKMIITSPKSLNLPGRSHPFSQSAPTGLNHMGWPEPTPDIALPDGALDTALRGDEAGSEEDLYEDVHSSSHHYSHTGGGGEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPANFVRLRVNQDEPADDEALGPGHQGTGDGGGTEAQGSRDQMRTNVINEILSTERDYIKHLRDICEGYLRQCRKRADMFSEEQLRIIFGNIEDIYRCQKAFVKALEQKFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACMELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIHSGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRVDMDSLQVVDLEDGKDRELHVSVRNAFRLCCGPSGESHLLCAKKPEQKQRWLKAFAREREQVRLDQETGFSITQLQRKQAMLNASKQQAMGKPKALGRPYYLARQKHPALPTSLPQQQVLVLAEPKRKPSTFWHSISRLAPFRK", "length": 1939, "header": "tr|A0ABI0NZ02-1|A0ABI0NZ02_BOVIN Isoform 1 of Rho guanine nucleotide exchange factor 4 OS=Bos taurus OX=9913 GN=ARHGEF4 PE=4 SV=1 CANONICAL=A0ABI0NZ02-1" }, "locus": { "chromosome": "2", "start_pos": 1863820, "end_pos": 1644119, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150183.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150183.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105348.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105348.1" } ] } }, { "isoform_ac": "A0ABI0P6B6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ02/entry#A0ABI0P6B6-1", "sequence": { "sequence": "MDSSSAYCPGLKTPEPSAHLPGHGDIEGQQLPSSPAEPEEQEWSQKTDHSDCETLSHQSESPSDTKTDPFESASDTESLPGDLLEGICLPSRGTSGDREAHKGCSDTPASGNPQEQYLTDVPGLDPKEELDLCLDFKEESHETGLRTFATVAGEVRAILQEDVAGPELELPPGRAALLTQDCARGLTGSYGLPPAKVVTVQDITGSSVFSSQKSRSESHLGTPLVWPLLLWCTEQSQSWPNIHNRQRGCQLSPRSPLNSTAPLGARAGKKCPPDPTSKTGLLCSQYSFDTTCWLPLGTSCLLHAKFYHSVPENSYDEGRALPRHCRWLTRTLNRAHSIAEFPLRNSEDPLGQNFVKFGTHLKEGTEAERAPITQTPLHPVPTQLSHLLPTSQRKTLPLKDQYKLRALNWKRASQDTPSEGLWLENQLGQDSRSCPVSSCLTAELVSLTTEEVPVPAKCKSGHGPESRPGEPQGPGQAPDAEDVSDAQKHLQDISAEPGNQTSNYTSKYILSEKRKPSARAKFPNHPSKSGSLVWNRDWGVCSRVIDNSYAPETTLKSSTADTLKKAEDVMVPDPSVTKNALQGFSGVAGATMSHCSCGDEECEQGHKGDTISFAEGLQTEPKADTSSRGTLIIIAVEQKGLQATRKKMGPLLRTQSCEFLEERPGSPHSAGATPCESPLAGKPKTCGNECELPAACSLRGNDGALRQVAQASESGIVLIPQAASEDWPPGRRKTSQEHAGDMLSTGVPMEENQPEASQSSRIPAAREEATRKPEACGPHPSGSRGPPSPEDTRRVCAAEGDADTDKQPGAQARARKSALQQPRPPHQLRQASREPGKRLAFPKVISFRKGKPLAAESPGGGHPGDSSGLKELCSDRQPPTGSAQSASGQAGTPCNAHASTLPVIGLQGLSQGAPGLMEVGRVDTPGDLGSRRQSSESCDAKRLKTPEKRLRARLASAHKTFASFFESRVLEKENTGQCSSCSLKDQKEKSRLRQSSWRTFLKSKDAQGSKRPSLVSLIPGPEILNTPSRFPPETNSHCEKQAEHKESYVFRDHWTPTHSPIPLSSGNLSSSDNRRKSEPTIKCTSTQESGEYIAPSTFPEKSWPMSPTSPGSQQAGISHTLPSSSTCCLAQGSQSVPSKPLSPKPQSLRPGAQGADFHYPEKGRAISVVSLGSYSHVDNSSEAPGNPKMSQAWISLLLSLQALDQGEQKEESGKRGQHPCGVSTAPSLKDLLGSESHMLWEEQPGKKPSCFQDLKAFHTEPAPGPFSTAEVGTWILPFISAEDVPRETPSQPRRIPQHSCISLDDLWLEKTQRRKLKKQAQFERKTHAHKDGVQCWRKMIITSPKSLNLPGRSHPFSQSAPTGLNHMGWPEPTPDIALPDGALDTALRGDEAGSEEDLYEDVHSSSHHYSHTGGGGEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPANFVRLRVNQDEPADDEALGPGHQGTGDGGGTEAQGSRDQMRTNVINEILSTERDYIKHLRDICEGYLRQCRKRADMFSEEQLRIIFGNIEDIYRCQKAFVKALEQKFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACMELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIHSGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRVDMDSLQVVDLEDGKDRELHVSVRNAFRLCCGPSGESHLLCAKKPEQKQRWLKAFAREREQVRLDQETGFSITQLQRKQAMLNASKQQAMGKPKALGRPYYLARQKHPALPTSLPQQQVLVLAEPKRKPSTFWHSISRLAPFRK", "length": 1925, "header": "tr|A0ABI0P6B6-1|A0ABI0P6B6_BOVIN Computationally mapped isoform of Rho guanine nucleotide exchange factor 4 OS=Bos taurus OX=9913 GN=ARHGEF4 PE=4 SV=1 CANONICAL=A0ABI0NZ02-1" }, "locus": { "chromosome": "2", "start_pos": 1863820, "end_pos": 1641708, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151022.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151022.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106524.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106524.1" } ] } }, { "isoform_ac": "F1MAZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ02/entry#F1MAZ5-1", "sequence": { "sequence": "MMSAGPERRPCGGGDGAEDAARPSARPSPGPGPGSLAPSPGSPGAAAAQPPANLWLELGPACTRAQQCPSESSGQTSGDLGTSSSSGGGSSAGLSPGSDSDSSGVVCGGRGGSGGMRGALSRSWSLESLRSATAALPDGALDTALRGDEAGSEEDLYEDVHSSSHHYSHTGGGGEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPANFVRLRVNQDEPADDEALGPGHQGTGDGGGTEAQGSRDQMRTNVINEILSTERDYIKHLRDICEGYLRQCRKRADMFSEEQLRIIFGNIEDIYRCQKAFVKALEQKFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACMELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIHSGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRVDMDSLQVVDLEDGKDRELHVSVRNAFRLCCGPSGESHLLCAKKPEQKQRWLKAFAREREQVRLDQETGFSITQLQRKQAMLNASKQQAMGKPKALGRPYYLARQKHPALPTSLPQQQVLVLAEPKRKPSTFWHSISRLAPFRK", "length": 683, "header": "tr|F1MAZ5-1|A0ABI0NZ02_BOVIN Computationally mapped isoform of Rho guanine nucleotide exchange factor 4 OS=Bos taurus OX=9913 GN=ARHGEF4 PE=4 SV=3 CANONICAL=A0ABI0NZ02-1" }, "locus": { "chromosome": "2", "start_pos": 1863820, "end_pos": 1753126, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021041.7", "url": "https://www.ensembl.org/id/ENSBTAT00000021041.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021041.6", "url": "https://www.ensembl.org/id/ENSBTAP00000021041.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1387, "start_aa": "Thr", "end_pos": 1387, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1387", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:505852", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505852", "resource": "KEGG Pathway" }, { "id": "R-BTA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-BTA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-BTA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-BTA-9958810", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958810", "resource": "Reactome", "description": "SRC activates STAT3 in a quantitative manner, through Cadherin-11 (CDH11), RAC1 and gp130 (IL6ST)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZ02", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ02" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZ02", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ02" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZ02", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1081, "end_pos": 1083, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1193, "end_pos": 1195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1878, "end_pos": 1880, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NZ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ02" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 1533, "end_pos": 1717, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NZ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ02" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 1748, "end_pos": 1855, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NZ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ02" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 1442, "end_pos": 1501, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1387 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1081, "end_pos": 1083 }, { "start_pos": 1193, "end_pos": 1195 }, { "start_pos": 1878, "end_pos": 1880 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 513, "end_pos": 515 }, { "start_pos": 517, "end_pos": 519 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NXQ0-1", "uniprot_ac": "A0ABI0NXQ0", "uniprot_id": "A0ABI0NXQ0_BOVIN", "mass": { "chemical_mass": 60806.0, "monoisotopic_mass": 60806.0 }, "refseq": { "ac": "NP_001192872", "name": "sodium-coupled neutral amino acid transporter 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192872" }, "gene_names": [ { "name": "SLC38A4", "type": "recommended", "evidence": [ { "id": "A0ABI0NXQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ0" } ] }, { "name": "Ata3", "type": "synonym", "evidence": [ { "id": "NP_001192872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192872" } ] }, { "name": "SLC38A4", "type": "synonym", "evidence": [ { "id": "NP_001192872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192872" } ] } ], "protein_names": [ { "name": "Solute carrier family 38 member 4", "type": "synonym", "evidence": [ { "id": "A0ABI0NXQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ0/entry#names_and_taxonomy" } ] }, { "name": "amino acid transport system A3", "type": "synonym", "evidence": [ { "id": "NP_001192872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192872" } ] }, { "name": "sodium-coupled neutral amino acid transporter 4", "type": "synonym", "evidence": [ { "id": "NP_001192872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192872" } ] } ], "function": [ { "annotation": "This is the first report on the imprinting status of SLC38A4 and the imprinting appears to be species-specific. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001192872", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192872" }, { "database": "PubMed", "id": "17064418", "url": "https://glygen.org/publication/PubMed/17064418" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXQ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC38A4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ0", "locus": { "chromosome": "5", "start_pos": 33484162, "end_pos": 33400506, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014197", "url": "https://www.ensembl.org/id/ENSBTAG00000014197" } ] } } ], "crossref": [ { "id": "ENSBTAG00000014197", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014197", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "527476", "url": "https://www.ncbi.nlm.nih.gov/gene/527476", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:527476", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527476", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QFANDDA", "url": "https://omabrowser.org/oma/group/QFANDDA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MM24", "url": "https://www.orthodb.org/?gene=F1MM24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950:SF222", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950:SF222", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-352230", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-352230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192872", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192872", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPF9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXQ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MM24", "url": "https://www.uniprot.org/uniprotkb/F1MM24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MM24-1", "url": "https://www.uniprot.org/uniprotkb/F1MM24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPMELSNVNIEPDDESISGESIQDSYTRMGNLEKAAMSSQFTNEDAESQKFLTNGFLGKKKLADYDDEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAVLSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFISITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLVIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPILDHSVGNLTFNNTVPMHVVMLLNNTESSGVNFMMDYTHQNAAGLDENQAKGSLHGSGVEFEAHSDDKCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRRKMQTVSNVSITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTFDTPLLMVRLAVLMAVTLTVPIVLFPIRTSVTTLLFPKRPFSWIRHFLIAAIIIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKEPFRSPQKVGALIFLVVGIIFMMGSMALIIIDWIYDPPNSKHH", "length": 547, "header": "tr|A0ABI0NXQ0-1|A0ABI0NXQ0_BOVIN Isoform 1 of Solute carrier family 38 member 4 OS=Bos taurus OX=9913 GN=SLC38A4 PE=4 SV=1 CANONICAL=A0ABI0NXQ0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPF9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ0/entry#A0A3Q1LPF9-1", "sequence": { "sequence": "MDPMELSNVNIEPDDESISGESIQDSYTRMGNLEKAAMSSQFTNEDAESQKFLTNGFLGKKKLADYDDEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAVLSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFISITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLVIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPILDHSVGNLTFNNTVPMHVVMLLNNTESSGVNFMMDYTHQNAAGLDENQAKGSLHGSGVEFEAHSDDKCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRRKMQTVSNVSITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTFDTPLLMVRLAVLMAVTLTVPIVLFPIRTSVTTLLFPKRPFSWIRHFLIAAIIIALNNVLVILVPTIKYIFGFIGFNFPRGWHHLHDGKHGTHYN", "length": 502, "header": "tr|A0A3Q1LPF9-1|A0ABI0NXQ0_BOVIN Computationally mapped isoform of Solute carrier family 38 member 4 OS=Bos taurus OX=9913 GN=SLC38A4 PE=4 SV=2 CANONICAL=A0ABI0NXQ0-1" }, "locus": { "chromosome": "5", "start_pos": 33483851, "end_pos": 33449492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070473.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070473.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056803.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056803.2" } ] } }, { "isoform_ac": "A0ABI0NXQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ0/entry#A0ABI0NXQ0-1", "sequence": { "sequence": "MDPMELSNVNIEPDDESISGESIQDSYTRMGNLEKAAMSSQFTNEDAESQKFLTNGFLGKKKLADYDDEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAVLSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFISITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLVIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPILDHSVGNLTFNNTVPMHVVMLLNNTESSGVNFMMDYTHQNAAGLDENQAKGSLHGSGVEFEAHSDDKCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRRKMQTVSNVSITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTFDTPLLMVRLAVLMAVTLTVPIVLFPIRTSVTTLLFPKRPFSWIRHFLIAAIIIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKEPFRSPQKVGALIFLVVGIIFMMGSMALIIIDWIYDPPNSKHH", "length": 547, "header": "tr|A0ABI0NXQ0-1|A0ABI0NXQ0_BOVIN Isoform 1 of Solute carrier family 38 member 4 OS=Bos taurus OX=9913 GN=SLC38A4 PE=4 SV=1 CANONICAL=A0ABI0NXQ0-1" }, "locus": { "chromosome": "5", "start_pos": 33483888, "end_pos": 33449492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138720.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138720.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106022.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106022.1" } ] } }, { "isoform_ac": "F1MM24-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ0/entry#F1MM24-1", "sequence": { "sequence": "MDPMELSNVNIEPDDESISGESIQDSYTRMGNLEKAAMSSQFTNEDAESQKFLTNGFLGKKKLADYDDEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAVLSLYSVHLLLKTAKEGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLVIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPILDHSVGNLTFNNTVPMHVVMLLNNTESSGVNFMMDYTHQNAAGLDENQAKGSLHGSGVEFEAHSDDKCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRRKMQTVSNVSITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTFDTPLLMVRLAVLMAVTLTVPIVLFPIRTSVTTLLFPKRPFSWIRHFLIAAIIIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKEPFRSPQKVGALIFLVVGIIFMMGSMALIIIDWIYDPPNSKHH", "length": 516, "header": "tr|F1MM24-1|A0ABI0NXQ0_BOVIN Computationally mapped isoform of Solute carrier family 38 member 4 OS=Bos taurus OX=9913 GN=SLC38A4 PE=4 SV=3 CANONICAL=A0ABI0NXQ0-1" }, "locus": { "chromosome": "5", "start_pos": 33483888, "end_pos": 33449492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018876.7", "url": "https://www.ensembl.org/id/ENSBTAT00000018876.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018876.6", "url": "https://www.ensembl.org/id/ENSBTAP00000018876.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Assessment of genomic imprinting of SLC38A4, NNAT, NAP1L5, and H19 in cattle.", "journal": "BMC genetics", "date": "2006-10-25", "authors": "Zaitoun Ismail, Khatib Hasan", "evidence": [ { "database": "RefSeq", "id": "NP_001192872", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192872" } ], "reference": [ { "type": "PubMed", "id": "17064418", "url": "https://glygen.org/publication/PubMed/17064418" } ] } ], "pathway": [ { "id": "bta:527476", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527476", "resource": "KEGG Pathway" }, { "id": "R-BTA-352230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-352230", "resource": "Reactome", "description": "Amino acid transport across the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M6YZH0-1", "protein_name": "Sodium-coupled neutral amino acid transporter 4", "gene_name": "slc38a4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MERMELKKVSAEMEDESSVDDSYRENMDSEKATINSQFLDEDDAESQKFLTNGLMKKKKYEEYNEEYHPGHASFGMSVFNLSNAIMGSGILGLSFAMANTGIILFVILLLGVAILSLYSVHLLLVTAKEGGSLIYEKLGERAFGWPGKMAAFGSITLQNIGAMSSYLFIVKYELPEVIRAFLGLEESSGEWYLNGNYVVVLVSIGIILPLSLLKNLGYLGYTSGFSLSCMVFFLGVLIYKKTILPCPLPFFFEHGSNVSINGSDAIALYGLHNASALAYMSETAANAVDPHTPLHDSVQFSAHPEDHQDMCTPKYFIFNSQTVYTVPILAFAFVCHPEVLPIYSELKNRSRRRMQSVSNLSILAMLVMYLLSALFGYLTFYDHVEAELLHTFTKVYKFDTMLLMVRLAVLTAVTLTVPIVLFPIRSSVITLCFAGKEFSWIRHFLIAAAILAFNNLLVIFVPTIRDIFGFIGSSAATMLIFILPAAFYLRLVKSLPMKSPQKISALIFLVVGIFFMIGSLSLIVLDWIHNPPGSKGAH", "length": 538 }, "evidence": [ { "id": "A0ABI0NXQ0", "url": "https://omabrowser.org/oma/group/A0ABI0NXQ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0YM52-1", "protein_name": "Solute carrier family 38 member 4", "gene_name": "SLC38A4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLESADHSVDLMEQQKVNIELEEQSNSGESLEDNYTELIDSEKAAIRSPFASDDAESQKFLTNGYLDKKKLEDYNEEYHRGRASFGMSSFNLSNAIMGSGILGLSYAMANTGIILFVVLLLSVAVLSLYSVHLLLKTSKEGGSLIYEKLGEKAFGWPGKCSVFISVTMQNIGAMSSYLFIIKYELPEVIRAFMKLEENSGEWYLNGNYLVILVTVVIILPLSLLKTLGYLGYTSGFSLTCMVFFVSVVIFKKFQIPCPLPIMDHGVGNWTATNITLPMHLVMLPNESLSSGVNFMMDNTVGHVPGLEEPRDTFLKSGVEYEAHSDSSDTCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRKRMQNVSNISITGMLIMYLLAGLFGYLTFYGEVEDELLHTYTRVYTFDALLLSVRLAVLVAVTLTVPLVLFPIRSSISALLFPKRPFSWIRHLLIAAVILAFNSMLVIFVPTIKDIFGFIGASSATMLIFILPSAFYLRLVKKEPMRSPQKIGALIFLIVGIIFMIGIKKVTSPHGLVYQKGDSFGKPVDKAEHQICCPCLSPSTCDGCRME", "length": 582 }, "evidence": [ { "id": "A0ABI0NXQ0", "url": "https://omabrowser.org/oma/group/A0ABI0NXQ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8R1S9-1", "protein_name": "Sodium-coupled neutral amino acid transporter 4", "gene_name": "Slc38a4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPMELNNVSIEPDGDSCSGDSIQDSYTGMENSDKDAMNSQFANEDAESQKFLTNGFLGKKKLADYADEHHPGMTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLTVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFISITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLVLFVSVGIILPLSLLKNLGYLGYTSGFSLSCMVFFVSVVIYKKFQIPCPLPALDHNNGNLTFNNTLPIHMISLPNDSESSGVNFMMDYAHHNPAGLDEKQVAGPLHSNGVEYEAQGAEKCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRRKMQTVSNISISGMLVMYLLAALFGYLSFYGDVEDELLHAYSKVYTFDTALLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPRKPFSWLKHFGIAAIIIALNNILVILVPTIKYIFGFIGASSATMLIFILPAAFYLKLVKKEPLRSPQKIGALVFLVTGIIFMMGSMALIILDWIYNPPNPNHH", "length": 547 }, "evidence": [ { "id": "A0ABI0NXQ0", "url": "https://omabrowser.org/oma/group/A0ABI0NXQ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q969I6-1", "protein_name": "Sodium-coupled neutral amino acid transporter 4", "gene_name": "SLC38A4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPMELRNVNIEPDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGKKKLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWIYDPPNSKHH", "length": 547 }, "evidence": [ { "id": "A0ABI0NXQ0", "url": "https://omabrowser.org/oma/group/A0ABI0NXQ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQ25-1", "protein_name": "Sodium-coupled neutral amino acid transporter 4", "gene_name": "Slc38a4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPIELRSVNIEPYEDSCSVDSIQSCYTGMGNSEKGAMDSQFANEDAESQKFLTNGFLGKKTLTDYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIVLFVIMLLTVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFISITMQNIGAMSSYLFIIKYELPEVIRVFMGLEENTGEWYLNGNYLVLFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPVLDHNNGNLTFNNTLPMHVIMLPNNSESTGMNFMVDYTHRDPEGLDEKPAAGPLHGSGVEYEAHSGDKCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLSFYGEVEDELLHAYSKVYTFDTALLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPRRPFSWVKHFGIAAIIIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAAFYLKLVKKEPLRSPQKIGALVFLVTGIIFMMGSMALIIIDWIYNPPNPDHH", "length": 547 }, "evidence": [ { "id": "A0ABI0NXQ0", "url": "https://omabrowser.org/oma/group/A0ABI0NXQ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXQ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXQ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "L-amino acid transmembrane transporter activity", "id": "GO:0015179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015179", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXQ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXQ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NXQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ0" }, { "id": "PF01490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amino acid transporter transmembrane", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 243, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 260, "end_pos": 262 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 369, "end_pos": 371 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 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"uniprot_ac": "A0ABI0NW60", "uniprot_id": "A0ABI0NW60_BOVIN", "mass": { "chemical_mass": 56928.0, "monoisotopic_mass": 56928.0 }, "refseq": { "ac": "XP_059733343", "name": "mixed lineage kinase domain-like protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059733343" }, "gene_names": [ { "name": "MLKL", "type": "recommended", "evidence": [ { "id": "A0ABI0NW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60" } ] }, { "name": "MLKL", "type": "synonym", "evidence": [ { "id": "XP_059733343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059733343" } ] } ], "protein_names": [ { "name": "Mixed lineage kinase domain-like protein", "type": "recommended", "evidence": [ { "id": "A0ABI0NW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60/entry#names_and_taxonomy" } ] }, { "name": "mixed lineage kinase domain-like protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_059733343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059733343" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW60", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MLKL", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60", "locus": { "chromosome": "18", "start_pos": 2122143, "end_pos": 2146121, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012216", "url": "https://www.ensembl.org/id/ENSBTAG00000012216" } ] } } ], "crossref": [ { "id": "ENSBTAG00000012216", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012216", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "790225", "url": "https://www.ncbi.nlm.nih.gov/gene/790225", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036537", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036537", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:790225", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:790225", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ESKVDWM", "url": "https://omabrowser.org/oma/group/ESKVDWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BGC6", "url": "https://www.orthodb.org/?gene=E1BGC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44329:SF298", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44329:SF298", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22215", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22215", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3295583", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3295583", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5213460", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5213460", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5675482", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5675482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_059733343", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059733343", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPP6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NW60", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NW60-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGC6", "url": "https://www.uniprot.org/uniprotkb/E1BGC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BGC6-1", "url": "https://www.uniprot.org/uniprotkb/E1BGC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQLKQIISLGRLIYNQCEEMKYCQKQCRRLGNRVQSLLQPLQMLQDQGERNLPPQITAALSRFQDALEEAKERIDKFSNKSNIQKFLTAGHDSIIFGGVNQRLSDVWEELSLLLQVDQWRHTSSLSLGVSWQQEDQQDAEEDRKAIQGLSEKETVKTLLMQLEETIEAVKNWMRSDSQKPKKGFPQDQIKEIKKEELPEADWILLKENESSTLYEGKYHESPVAIKVFNNSQAKDIGVVRHTFNNEIRTMKKFDSPNILRMFGICIDETVTPPQLSIVMEYCELGTLRELLDREKDLTLAKRIILAVEAARGLYRLHHSETPSELHRNISSTSFLVTKDYNVKLAGFELSKTQTSISRQTRGKAAERVSSAAYISPQRLENVYNKYDIKAEIYSFGIVLWEIATGKSPFEGCDSKKIYQLVAESRHREPVGEDCPSELQEIIDDCRAYEPSRRPSVKVRGVLKARILKWFAIPFSSGPHFVRTLHHDPSVLDGPT", "length": 496, "header": "tr|A0ABI0NW60-1|A0ABI0NW60_BOVIN Isoform 1 of Mixed lineage kinase domain-like protein OS=Bos taurus OX=9913 GN=MLKL PE=3 SV=1 CANONICAL=A0ABI0NW60-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPP6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60/entry#A0A3Q1LPP6-1", "sequence": { "sequence": "MDQLKQIISLGRLIYNQCEEMKYCQKQCRRLGNRVQSLLQPLQMLQDQGERNLPPQITAALSRFQDALEEAKERIDKFSNKSNIQKFLTAGHDSIIFGGVNQRLSDVWEELSLLLQVDQWRHTSSLSLGVSWQQEDQQDAEEDRKAIQGLSEKETVKTLLMQLEETIEAVKNWMRSDSQKPKKGFPQDQIKEIKKEELPEADWILLKENESSTLYEGKYHESPVAIKVFNNSQAKDIGVVRHTFNNEIRTMKKFDSPNILRMFGICIDETAIGSFPSVTPPQLSIVMEYCELGTLRELLDREKDLTLAKRIILAVEAARGLYRLHHSETPSELHRNISSTSFLVTKDYNVKLAGFELSKTQTSISRQTRGKAAERVSSAAYISPQRLENVYNKYDIKAEIYSFGIVLWEIATGKSPFEGCDSKKIYQLVAESRHREPVGEDCPSELQEIIDDCRAYEPSRRPSVKEILKRLSSFY", "length": 475, "header": "tr|A0A3Q1LPP6-1|A0ABI0NW60_BOVIN Computationally mapped isoform of Mixed lineage kinase domain-like protein OS=Bos taurus OX=9913 GN=MLKL PE=3 SV=2 CANONICAL=A0ABI0NW60-1" }, "locus": { "chromosome": "18", "start_pos": 2142285, "end_pos": 2123147, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082389.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082389.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056914.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056914.3" } ] } }, { "isoform_ac": "A0ABI0NW60-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60/entry#A0ABI0NW60-1", "sequence": { "sequence": "MDQLKQIISLGRLIYNQCEEMKYCQKQCRRLGNRVQSLLQPLQMLQDQGERNLPPQITAALSRFQDALEEAKERIDKFSNKSNIQKFLTAGHDSIIFGGVNQRLSDVWEELSLLLQVDQWRHTSSLSLGVSWQQEDQQDAEEDRKAIQGLSEKETVKTLLMQLEETIEAVKNWMRSDSQKPKKGFPQDQIKEIKKEELPEADWILLKENESSTLYEGKYHESPVAIKVFNNSQAKDIGVVRHTFNNEIRTMKKFDSPNILRMFGICIDETVTPPQLSIVMEYCELGTLRELLDREKDLTLAKRIILAVEAARGLYRLHHSETPSELHRNISSTSFLVTKDYNVKLAGFELSKTQTSISRQTRGKAAERVSSAAYISPQRLENVYNKYDIKAEIYSFGIVLWEIATGKSPFEGCDSKKIYQLVAESRHREPVGEDCPSELQEIIDDCRAYEPSRRPSVKVRGVLKARILKWFAIPFSSGPHFVRTLHHDPSVLDGPT", "length": 496, "header": "tr|A0ABI0NW60-1|A0ABI0NW60_BOVIN Isoform 1 of Mixed lineage kinase domain-like protein OS=Bos taurus OX=9913 GN=MLKL PE=3 SV=1 CANONICAL=A0ABI0NW60-1" }, "locus": { "chromosome": "18", "start_pos": 2142285, "end_pos": 2128162, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154279.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154279.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105837.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105837.1" } ] } }, { "isoform_ac": "E1BGC6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60/entry#E1BGC6-1", "sequence": { "sequence": "MDQLKQIISLGRLIYNQCEEMKYCQKQCRRLGNRVQSLLQPLQMLQDQGERNLPPQITAALSRFQDALEEAKERIDKFSNKSNIQKFLTAGHDSIIFGGVNQRLSDVWEELSLLLQVDQWRHTSSLSLGVSWQQEDQQDAEEDRKAIQGLSEKETVKTLLMQLEETIEAVKNWMRSDSQKPKKGFPQDQIKEIKKEELPEADWILLKENESSTLYEGKYHESPVAIKVFNNSQAKDIGVVRHTFNNEIRTMKKFDSPNILRMFGICIDETVTPPQLSIVMEYCELGTLRELLDREKDLTLAKRIILAVEAARGLYRLHHSETPSELHRNISSTSFLVTKDYNVKLAGFELSKTQTSISRQTRGKAAERVSSAAYISPQRLENVYNKYDIKAEIYSFGIVLWEIATGKSPFEGCDSKKIYQLVAESRHREPVGEDCPSELQEIIDDCRAYEPSRRPSVKEILKRLSSFY", "length": 468, "header": "tr|E1BGC6-1|A0ABI0NW60_BOVIN Computationally mapped isoform of Mixed lineage kinase domain-like protein OS=Bos taurus OX=9913 GN=MLKL PE=3 SV=3 CANONICAL=A0ABI0NW60-1" }, "locus": { "chromosome": "18", "start_pos": 2142285, "end_pos": 2123147, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016202.7", "url": "https://www.ensembl.org/id/ENSBTAT00000016202.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016202.6", "url": "https://www.ensembl.org/id/ENSBTAP00000016202.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:790225", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:790225", "resource": "KEGG Pathway" }, { "id": "R-BTA-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3295583", "resource": "Reactome", "description": "TRP channels" }, { "id": "R-BTA-5213460", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5213460", "resource": "Reactome", "description": "RIPK1-mediated regulated necrosis" }, { "id": "R-BTA-5675482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5675482", "resource": "Reactome", "description": "Regulation of necroptotic cell death" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZV82-1", "protein_name": "Mixed lineage kinase domain-like protein", "gene_name": "Mlkl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKLGQIIKLGQLIYDQCEKMKYCKRQCRRLRNRVHGLLQPLQRLQAQEKKSLPSDITAALGRFEDVLKEARQQIEKFSQKSNIWKFATVGSDKILFHEVNEKLRDIWEELLLLLQVDQWKSDSEVSQPASWQQEDQQDAEEDGNENMKVILVKLQISMEEIKEALKQCSLKPMQEVPQDFQVKEIPKEDLGYPWTKLKTNKLSTIYRGEYYKSPVTIKVFNNPKAESVGIVRLTFNEEIKTMKKFDSPNILRIFGICIDQTVKPPEFSIVMEYCELGTLRELLDRDKDLTMSVRSLLVLRAARGLYRLHHSGTLHGNISSSSFLVAGGYQVKLAGFELSKTQTSISRATKSTKAERFSSTAYVSPERLQDPFCKYDTKAEIYSFGIVLWEIATGKIPFEGCDSEKIYELVAENKKQEPVGQDCPELLQEIINECRAHEPSNRPSADGILERLPAIEDSMDKKL", "length": 464 }, "evidence": [ { "id": "A0ABI0NW60", "url": "https://omabrowser.org/oma/group/A0ABI0NW60/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C6F2-1", "protein_name": "Mixed lineage kinase domain like pseudokinase", "gene_name": "MLKL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDIIEKVFSIAHAIHSQFEHVKCCKHQCQRLVERIHILLEPVRVLQAQPSWRISHHEEQMLTKLLQALGEAQKLVTKYSQTSWIQKFLSARSSGEEFVWVNRSLEDIAQGLSLLLQAEQKQALLEAFQAKICRRQDAEDLRDDKAFLDQVIASTKEPEDEAWEIQMGSQCMESKVDWMQGELNKIVRVMDSLKKVNVGKREDITEIERSQLTFHRHLQDTERYDLYEGEYLKYPVAIKTFKRPLTTDTVKVRDIFEKEIQTLKKFESPNILRMYGICIEEKDGIPCFSIVMEYCKHGTLREVLTKQQHLSWEIRIRMALGAARGLYRLHQTEEKSRLHGCICSSKFLVAGDYCVKLSGFELCETESSIKRKVSKKNFSQVCMLAYIAPENLMDVYYPYKRPCEIYSFGIVLWEIATSKIPFEGCPLQEIRDKICEHRYQEPVGEDCPEELEKVINQCRAFDPFQRPSAEQIVDLLADLEKRRIQCS", "length": 486 }, "evidence": [ { "id": "A0ABI0NW60", "url": "https://omabrowser.org/oma/group/A0ABI0NW60/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8NB16-1", "protein_name": "Mixed lineage kinase domain-like protein", "gene_name": "MLKL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENLKHIITLGQVIHKRCEEMKYCKKQCRRLGHRVLGLIKPLEMLQDQGKRSVPSEKLTTAMNRFKAALEEANGEIEKFSNRSNICRFLTASQDKILFKDVNRKLSDVWKELSLLLQVEQRMPVSPISQGASWAQEDQQDADEDRRAFQMLRRDNEKIEASLRRLEINMKEIKETLRQYLPPKCMQEIPQEQIKEIKKEQLSGSPWILLRENEVSTLYKGEYHRAPVAIKVFKKLQAGSIAIVRQTFNKEIKTMKKFESPNILRIFGICIDETVTPPQFSIVMEYCELGTLRELLDREKDLTLGKRMVLVLGAARGLYRLHHSEAPELHGKIRSSNFLVTQGYQVKLAGFELRKTQTSMSLGTTREKTDRVKSTAYLSPQELEDVFYQYDVKSEIYSFGIVLWEIATGDIPFQGCNSEKIRKLVAVKRQQEPLGEDCPSELREIIDECRAHDPSVRPSVDEILKKLSTFSK", "length": 471 }, "evidence": [ { "id": "A0ABI0NW60", "url": "https://omabrowser.org/oma/group/A0ABI0NW60/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D2Y4-1", "protein_name": "Mixed lineage kinase domain-like protein", "gene_name": "Mlkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDKLGQIIKLGQLIYEQCEKMKYCRKQCQRLGNRVHGLLQPLQRLQAQGKKNLPDDITAALGRFDEVLKEANQQIEKFSKKSHIWKFVSVGNDKILFHEVNEKLRDVWEELLLLLQVYHWNTVSDVSQPASWQQEDRQDAEEDGNENMKVILMQLQISVEEINKTLKQCSLKPTQEIPQDLQIKEIPKEHLGPPWTKLKTSKMSTIYRGEYHRSPVTIKVFNNPQAESVGIVRFTFNDEIKTMKKFDSPNILRIFGICIDQTVKPPEFSIVMEYCELGTLRELLDREKDLTMSVRSLLVLRAARGLYRLHHSETLHRNISSSSFLVAGGYQVKLAGFELSKTQNSISRTAKSTKAERSSSTIYVSPERLKNPFCLYDIKAEIYSFGIVLWEIATGKIPFEGCDSKKIRELVAEDKKQEPVGQDCPELLREIINECRAHEPSQRPSVDGRSLSGRERILERLSAVEESTDKKV", "length": 472 }, "evidence": [ { "id": "A0ABI0NW60", "url": "https://omabrowser.org/oma/group/A0ABI0NW60/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW60", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW60", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW60", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60" } ], "pmid": "" }, { "name": "necroptotic signaling pathway", "id": "GO:0097527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097527", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW60", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60" } ], "pmid": "" }, { "name": "necroptotic process", "id": "GO:0070266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070266", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW60", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60" } ], "pmid": "" }, { "name": "execution phase of necroptosis", "id": "GO:0097528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097528", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW60", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW60", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW60", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW60", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW60" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 200, "end_pos": 471, "start_aa": "Glu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 209, "end_pos": 211 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 329, "end_pos": 331 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NYB1-1", "uniprot_ac": "A0ABI0NYB1", "uniprot_id": "A0ABI0NYB1_BOVIN", "mass": { "chemical_mass": 39635.0, "monoisotopic_mass": 39635.0 }, "refseq": { "ac": "XP_010806026", "name": "F-box only protein 16 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806026" }, "gene_names": [ { "name": "FBXO16", "type": "recommended", "evidence": [ { "id": "A0ABI0NYB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYB1" } ] }, { "name": "FBXO16", "type": "synonym", "evidence": [ { "id": "XP_010806026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806026" } ] } ], "protein_names": [ { "name": "F-box only protein 16 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010806026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806026" } ] }, { "name": "F-box protein 16", "type": "synonym", "evidence": [ { "id": "A0ABI0NYB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYB1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYB1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYB1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FBXO16", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYB1", "locus": { "chromosome": "8", "start_pos": 10293434, "end_pos": 10243225, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000034626", "url": "https://www.ensembl.org/id/ENSBTAG00000034626" } ] } } ], "crossref": [ { "id": "ENSBTAG00000034626", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000034626", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22172", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22172", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "768246", "url": "https://www.ncbi.nlm.nih.gov/gene/768246", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052805", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052805", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46857", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46857", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46857:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46857:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010806026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806026", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPZ2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUX6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWB3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMI4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMI4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYB1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYB1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P7S9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P7S9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2L2", "url": "https://www.uniprot.org/uniprotkb/F1N2L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2L2-1", "url": "https://www.uniprot.org/uniprotkb/F1N2L2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMAFAPPKNTDGPKMQTKMSTWTPLNHQLLNDRVFEERRALLGKWFDKWTDTQRRRILTSLLERCSLSQQKFCCRKLQEKIPAEALDFTTKLPRVLSLHIFSFLDPRSLCRCAQVSWHWKNLTELDQLWMLKCLRFNWYINFSPTPYEQGVWKKHYIQMVKELHVTKPKTPPKDGFVIADVQPIRSSSPEGKLSPSSAFRSSSSLRKKTHPGEKELPPWRSSDKHPTDIIRFNYLDNCDPIEHSWQGRRKRHEMTPAFNRQSRDKKNKSQDRSKLRKAQSLSSLNAEPRASLHVPAHLAWLPHQPLGLPATEAATKTLTRHLQRLSGLQSSPQAFPQQLM", "length": 340, "header": "tr|A0ABI0NYB1-1|A0ABI0NYB1_BOVIN Isoform 1 of F-box protein 16 OS=Bos taurus OX=9913 GN=FBXO16 PE=4 SV=1 CANONICAL=A0ABI0NYB1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYB1/entry#A0A3Q1LPZ2-1", "sequence": { "sequence": "MMAFAPPKNTDGPKMQTKMSTWTPLNHQLLNDRVFEERRALLGKWFDKWTDTQRRRILTSLLERCSLSQQKFCCRKLQEKIPAEALDFTTKLPRVLSLHIFSFLDPRSLCRCAQVSWHWKNLTELDQLWMLKCLRFNWYINFSPTPYEQGVWKKHYIQMVKELHVTKPKTPPKDGFVIADVQPIRSSSPEGKLSPSSAFRSSSSLRKKTHPGEKELPPWRSSDKHPTDIIRFNYLDNCDPIEHSWQGRRKRHEMTPAFNRQSRDKKNKSQDRSKLRKAQSL", "length": 281, "header": "tr|A0A3Q1LPZ2-1|A0ABI0NYB1_BOVIN Computationally mapped isoform of F-box protein 16 OS=Bos taurus OX=9913 GN=FBXO16 PE=4 SV=3 CANONICAL=A0ABI0NYB1-1" }, "locus": { "chromosome": "8", "start_pos": 10280630, "end_pos": 10248662, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066380.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066380.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059093.3", "url": "https://www.ensembl.org/id/ENSBTAP00000059093.3" } ] } }, { "isoform_ac": "A0A3Q1LUX6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYB1/entry#A0A3Q1LUX6-1", "sequence": { "sequence": "MMAFAPPKNTDGPKMQTKMSTWTPLNHQLLNDRVFEERRALLGKWFDKWTDTQRRRILTSLLERCSLSQQKFCCRKLQEKIPAEALDFTTKLPRVLSLHIFSFLDPRSLCRCAQVSWHWKNLTELDQLWMLKCLRFNWYINFSPTPYEQGVWKKHYIQMVKELHVTKPKTPPKDGFVIADVQPIRSSSPEGKLSPSSAFRSSSSLRKKTHPGEKELPPWRSSDKHPTDIIRFNYLDNCDPIEHSWQGRRKRHEMTPAFNRQSRDKKNKSQDRSKLRKAQSLGTQIQSLVQEDPTCHGATKLVCHNC", "length": 306, "header": "tr|A0A3Q1LUX6-1|A0ABI0NYB1_BOVIN Computationally mapped isoform of F-box protein 16 OS=Bos taurus OX=9913 GN=FBXO16 PE=4 SV=3 CANONICAL=A0ABI0NYB1-1" }, "locus": { "chromosome": "8", "start_pos": 10317373, "end_pos": 10248662, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067571.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067571.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064365.3", "url": "https://www.ensembl.org/id/ENSBTAP00000064365.3" } ] } }, { "isoform_ac": "A0A3Q1LWB3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYB1/entry#A0A3Q1LWB3-1", "sequence": { "sequence": "MMAFAPPKNTDGPKMQTKMSTWTPLNHQLLNDRVFEERRALLGKWFDKWTDTQRRRILTSLLERCSLSQQKFCCRKLQEKIPAEALDFTTKLPRVLSLHIFSFLDPRSLCRCAQVSWHWKNLTELDQLWMLKCLRFNWYINFSPTPYEQGVWKKHYIQMVKELHVTKPKTPPKDGFVIADVQPIRSSSPEGKLSPSSAFRSSSSLRKKTHPGEKELPPWRSSDKHPTDIIRFNYLDNCDPIEHSWQGRRKRHEMTPAFNRQSRDKKNKSQDRSKLRKAQSLMLRSPSSLAP", "length": 291, "header": "tr|A0A3Q1LWB3-1|A0ABI0NYB1_BOVIN Computationally mapped isoform of F-box protein 16 OS=Bos taurus OX=9913 GN=FBXO16 PE=4 SV=2 CANONICAL=A0ABI0NYB1-1" }, "locus": { "chromosome": "8", "start_pos": 10293156, "end_pos": 10248662, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077331.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077331.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061508.3", "url": "https://www.ensembl.org/id/ENSBTAP00000061508.3" } ] } }, { "isoform_ac": "A0AAA9SMI4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYB1/entry#A0AAA9SMI4-1", "sequence": { "sequence": "MMAFAPPKNTDGPKMQTKMSTWTPLNHQLLNDRVFEERRALLGKWFDKWTDTQRRRILTSLLERCSLSQQKFCCRKLQEKIPAEALDFTTKLPRVLSLHIFSFLDPRSLCRCAQVSWHWKNLTELDQLWMLKCLRFNWYINFSPTPYEQGVWKKHYIQMVKELHVTKPKTPPKDGFVIADVQPIRSSSPEGKLSPSSAFRSSSSLRKKTHPGEKELPPWRSSDKHPTDIIRFNYLDNCDPIEHSWQGRRKRHEMTPAFNRQSRDKKNKSQDRSKLRKAQSLSTRFGLKQTRFNA", "length": 294, "header": "tr|A0AAA9SMI4-1|A0ABI0NYB1_BOVIN Computationally mapped isoform of F-box protein 16 OS=Bos taurus OX=9913 GN=FBXO16 PE=4 SV=1 CANONICAL=A0ABI0NYB1-1" }, "locus": { "chromosome": "8", "start_pos": 10287274, "end_pos": 10248662, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096107.2", "url": "https://www.ensembl.org/id/ENSBTAT00000096107.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083973.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083973.1" } ] } }, { "isoform_ac": "A0ABI0NYB1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYB1/entry#A0ABI0NYB1-1", "sequence": { "sequence": "MMAFAPPKNTDGPKMQTKMSTWTPLNHQLLNDRVFEERRALLGKWFDKWTDTQRRRILTSLLERCSLSQQKFCCRKLQEKIPAEALDFTTKLPRVLSLHIFSFLDPRSLCRCAQVSWHWKNLTELDQLWMLKCLRFNWYINFSPTPYEQGVWKKHYIQMVKELHVTKPKTPPKDGFVIADVQPIRSSSPEGKLSPSSAFRSSSSLRKKTHPGEKELPPWRSSDKHPTDIIRFNYLDNCDPIEHSWQGRRKRHEMTPAFNRQSRDKKNKSQDRSKLRKAQSLSSLNAEPRASLHVPAHLAWLPHQPLGLPATEAATKTLTRHLQRLSGLQSSPQAFPQQLM", "length": 340, "header": "tr|A0ABI0NYB1-1|A0ABI0NYB1_BOVIN Isoform 1 of F-box protein 16 OS=Bos taurus OX=9913 GN=FBXO16 PE=4 SV=1 CANONICAL=A0ABI0NYB1-1" }, "locus": { "chromosome": "8", "start_pos": 10293326, "end_pos": 10248662, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154391.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154391.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105216.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105216.1" } ] } }, { "isoform_ac": "A0ABI0P7S9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYB1/entry#A0ABI0P7S9-1", "sequence": { "sequence": "MMAFAPPKNTDGPKMQTKMSTWTPLNHQLLNDRFDKWTDTQRRRILTSLLERCSLSQQKFCCRKLQEKIPAEALDFTTKLPRVLSLHIFSFLDPRSLCRCAQVSWHWKNLTELDQLWMLKCLRFNWYINFSPTPYEQGVWKKHYIQMVKELHVTKPKTPPKDGFVIADVQPIRSSSPEGKLSPSSAFRSSSSLRKKTHPGEKELPPWRSSDKHPTDIIRFNYLDNCDPIEHSWQGRRKRHEMTPAFNRQSRDKKNKSQDRSKLRKAQSLSSLNAEPRASLHVPAHLAWLPHQPLGLPATEAATKTLTRHLQRLSGLQSSPQAFPQQLM", "length": 328, "header": "tr|A0ABI0P7S9-1|A0ABI0P7S9_BOVIN Computationally mapped isoform of F-box protein 16 OS=Bos taurus OX=9913 GN=FBXO16 PE=4 SV=1 CANONICAL=A0ABI0NYB1-1" }, "locus": { "chromosome": "8", "start_pos": 10293326, "end_pos": 10248662, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149158.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149158.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107312.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107312.1" } ] } }, { "isoform_ac": "F1N2L2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYB1/entry#F1N2L2-1", "sequence": { "sequence": "MMAFAPPKNTDGPKMQTKMSTWTPLNHQLLNDRVFEERRALLGKWFDKWTDTQRRRILTSLLERCSLSQQKFCCRKLQEKIPAEALDFTTKLPRVLSLHIFSFLDPRSLCRCAQVSWHWKNLTELDQLWMLKCLRFNWYINFSPTPYEQGVWKKHYIQMVKELHVTKPKTPPKDGFVIADVQPIRSSSPEGKLSPSSAFRSSSSLRKKTHPGEKELPPWRSSDKHPTDIIRFNYLDNCDPIEHSWQGRRKRHEMTPAFNRQSRDKKNKSQDRSKLRKAQSLAPNLCSTCLLSLKT", "length": 295, "header": "tr|F1N2L2-1|A0ABI0NYB1_BOVIN Computationally mapped isoform of F-box protein 16 OS=Bos taurus OX=9913 GN=FBXO16 PE=4 SV=4 CANONICAL=A0ABI0NYB1-1" }, "locus": { "chromosome": "8", "start_pos": 10311142, "end_pos": 10248662, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049038.5", "url": "https://www.ensembl.org/id/ENSBTAT00000049038.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000045982.5", "url": "https://www.ensembl.org/id/ENSBTAP00000045982.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NYB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYB1" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 132, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 141, "end_pos": 143 }, { "start_pos": 267, "end_pos": 269 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NYC3-1", "uniprot_ac": "A0ABI0NYC3", "uniprot_id": "A0ABI0NYC3_BOVIN", "mass": { "chemical_mass": 40264.0, "monoisotopic_mass": 40264.0 }, "refseq": {}, "gene_names": [ { "name": "MECR", "type": "recommended", "evidence": [ { "id": "A0ABI0NYC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3" } ] } ], "protein_names": [ { "name": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0ABI0NYC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3/entry#names_and_taxonomy" } ] }, { "name": "1.3.1.104", "type": "synonym", "evidence": [ { "id": "A0ABI0NYC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3/entry#names_and_taxonomy" } ] }, { "name": "2-enoyl thioester reductase", "type": "synonym", "evidence": [ { "id": "A0ABI0NYC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3/entry#names_and_taxonomy" } ] }, { "name": "Nuclear receptor-binding factor 1", "type": "synonym", "evidence": [ { "id": "A0ABI0NYC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Displays a preference for medium-chain over short- and long-chain substrates. May provide the octanoyl chain used for lipoic acid biosynthesis, regulating protein lipoylation and mitochondrial respiratory activity particularly in Purkinje cells. Involved in iron homeostasis; affecting Fe-S cluster assembly and ceramide metabolism. Required for proper morphology and bioenergetic functions of mitochondria. Required for maintenance of neurons.", "evidence": [ { "database": "UniProtKB", "id": "F1MEY2", "url": "https://www.uniprot.org/uniprotkb/F1MEY2#function" }, { "database": "UniProtKB", "id": "ARBA00053553", "url": "https://www.uniprot.org/uniprotkb/ARBA00053553#function" }, { "database": "UniProtKB", "id": "A0ABI0NYC3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3#function" }, { "database": "UniProtKB", "id": "A0ABI0P1A6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A6#function" }, { "database": "UniProtKB", "id": "A0AAA9RUC1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUC1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYC3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { 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"categories": [ "Protein Classification" ] }, { "id": "PF00107", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00107", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-77346", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77346", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "22564", "url": "https://www.rhea-db.org/rhea/22564", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41812", "url": "https://www.rhea-db.org/rhea/41812", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41832", "url": "https://www.rhea-db.org/rhea/41832", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41848", "url": "https://www.rhea-db.org/rhea/41848", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41864", "url": "https://www.rhea-db.org/rhea/41864", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41880", "url": "https://www.rhea-db.org/rhea/41880", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41896", "url": "https://www.rhea-db.org/rhea/41896", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41912", "url": "https://www.rhea-db.org/rhea/41912", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LRT6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RUC1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RUC1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXM4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXM4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYC3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYC3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1A6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1A6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MEY2", "url": "https://www.uniprot.org/uniprotkb/F1MEY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MEY2-1", "url": "https://www.uniprot.org/uniprotkb/F1MEY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWVCGALCRTRAPAQLGQRLLPESRRRRPASASFSASAEPSRVRALVYGHHGDPAKVVELKNLELAAVGGSDVHVKMLAAPINPSDINMIQGNYGLLPQLPAVGGNEGVGQVVAVGSGVTGVKPGDWVIPANPGLGTWRTEAVFGEEELITVPSDIPLQSAATLGVNPCTAYRMLVDFERLRPGDSIIQNASNSGVGQAVIQIAAARGLRTINVLRDRPDLQKLTDRLKNLGANHVVTEEELRKPEMKSFFKDVPQPRLALNCVGGKSSTELLRHLAPGGTMVTYGGMAKQPVIASVSQLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSEVPLQDYLCALEASTQPFVSSKQILTM", "length": 373, "header": "tr|A0ABI0NYC3-1|A0ABI0NYC3_BOVIN Isoform 1 of Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Bos taurus OX=9913 GN=MECR PE=3 SV=1 CANONICAL=A0ABI0NYC3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LRT6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3/entry#A0A3Q1LRT6-1", "sequence": { "sequence": "MTYLAASVSELTGGNMWVCGALCRTRAPAQLGQRLLPESRRRRPASASFSASAEPSRVRALVYGHHGDPAKVVELKNLELAAVGGSDVHVKMLAAPINPSDINMIQGNYGLLPQLPAVGGNEGVGQVVAVGSGVTGVKPGDWVIPANPGLGTWRTEAVFGEEELITVPSDIPLQSAATLGVNPCTAYRMLVDFERLRPGGRMSAWVLENRRKPHGGAHPGKPLRGHIPSNSGWNFVTQQKSCGAVLSSGTAELRQDRHSPCVFSKMLNLALVLPLSTARALSSPHTCPPMHRPSNALGRQSGELRAPVGLTDWQLTSQISRLFIRETGRGFHHPECIQQWSGASGHPDRGRPGPEDHQRAPGQAQSHSWARVCLHNTLKSLLKRRGKGSGVLSFQ", "length": 395, "header": "tr|A0A3Q1LRT6-1|A0ABI0NYC3_BOVIN Computationally mapped isoform of Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Bos taurus OX=9913 GN=MECR PE=3 SV=1 CANONICAL=A0ABI0NYC3-1" }, "locus": { "chromosome": "2", "start_pos": 124361541, "end_pos": 124332554, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067139.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067139.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059891.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059891.2" } ] } }, { "isoform_ac": "A0AAA9RUC1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3/entry#A0AAA9RUC1-1", "sequence": { "sequence": "MTYLAASVSELTGGNMWVCGALCRTRAPAQLGQRLLPESRRRRPASASFSASAEPSRVRALVYGHHGDPAKVVELKNLELAAVGGSDVHVKMLAAPINPSDINMIQGNYGLLPQLPAVGGNEGVGQVVAVGSGVTGVKPGDWVIPANPGLGTWRTEAVFGEEELITVPSDIPLQSAATLGVNPCTAYRMLVDFERLRPGDSIIQNASNSGVGQAVIQIAAARGLRTINVLRDRPDLQKLTDRLKNLGANHVVTEEELRKPEMKSFFKDVPQPRLALNCVGGKSSTELLRHLAPGGTMVTYGGMAKQPVIASVSQLIFKDLKLRGFWLSQWKKDHSPVFPSITSESALPRRWPKYWSFSFSISPSSEYSGLISCRTDWFDLLAVQGTLKSLLQHSSSISDWETKIPHGLKARSKKIFFNSHNCLNYC", "length": 426, "header": "tr|A0AAA9RUC1-1|A0ABI0NYC3_BOVIN Computationally mapped isoform of Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Bos taurus OX=9913 GN=MECR PE=3 SV=1 CANONICAL=A0ABI0NYC3-1" }, "locus": { "chromosome": "2", "start_pos": 124367286, "end_pos": 124332554, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097629.2", "url": "https://www.ensembl.org/id/ENSBTAT00000097629.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075718.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075718.1" } ] } }, { "isoform_ac": "A0AAA9TXM4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3/entry#A0AAA9TXM4-1", "sequence": { "sequence": "MTYLAASVSELTGGNMWVCGALCRTRAPAQLGQRLLPESRRRRPASASFSASAEPSRVRALVYGHHGDPAKVVELKNLELAAVGGSDVHVKMLAAPINPSDINMIQGNYGLLPQLPAVGGNEGVGQVVAVGSGVTGVKPGDWVIPANPGLGTWRTEAVFGEEELITVPSDIPLQSAATLGVNPCTAYRMLVDFERLRPGGRMSAWVLENRRKPHGGAHPGKPLRGHIPSNSGWNFVTQQKSCGAVLSSGTAELRQDRHSPCVFSKMLNLALVLPLSTARALSSPHTCPPMHRPSNALGRQSGELRAPVGLTDWQLTSQISRLFIRETGRQGSERSQRHAKQPSAQGLAYRAVQGHPWYHLPS", "length": 362, "header": "tr|A0AAA9TXM4-1|A0ABI0NYC3_BOVIN Computationally mapped isoform of Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Bos taurus OX=9913 GN=MECR PE=3 SV=1 CANONICAL=A0ABI0NYC3-1" }, "locus": { "chromosome": "2", "start_pos": 124358522, "end_pos": 124332554, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131857.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131857.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103408.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103408.1" } ] } }, { "isoform_ac": "A0ABI0NYC3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3/entry#A0ABI0NYC3-1", "sequence": { "sequence": "MWVCGALCRTRAPAQLGQRLLPESRRRRPASASFSASAEPSRVRALVYGHHGDPAKVVELKNLELAAVGGSDVHVKMLAAPINPSDINMIQGNYGLLPQLPAVGGNEGVGQVVAVGSGVTGVKPGDWVIPANPGLGTWRTEAVFGEEELITVPSDIPLQSAATLGVNPCTAYRMLVDFERLRPGDSIIQNASNSGVGQAVIQIAAARGLRTINVLRDRPDLQKLTDRLKNLGANHVVTEEELRKPEMKSFFKDVPQPRLALNCVGGKSSTELLRHLAPGGTMVTYGGMAKQPVIASVSQLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSEVPLQDYLCALEASTQPFVSSKQILTM", "length": 373, "header": "tr|A0ABI0NYC3-1|A0ABI0NYC3_BOVIN Isoform 1 of Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Bos taurus OX=9913 GN=MECR PE=3 SV=1 CANONICAL=A0ABI0NYC3-1" }, "locus": { "chromosome": "2", "start_pos": 124368419, "end_pos": 124332599, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136878.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136878.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105243.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105243.1" } ] } }, { "isoform_ac": "A0ABI0P1A6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3/entry#A0ABI0P1A6-1", "sequence": { "sequence": "MTYLAASVSELTGGNMWVCGALCRTRAPAQLGQRLLPESRRRRPASASFSASAEPSRVRALVYGHHGDPAKVVELKNLELAAVGGSDVHVKMLAAPINPSDINMIQGNYGLLPQLPAVGGNEGVGQVVAVGSGVTGVKPGDWVIPANPGLGTWRTEAVFGEEELITVPSDIPLQSAATLGVNPCTAYRMLVDFERLRPGDSIIQNASNSGVGQAVIQIAAARGLRTINVLRDRPDLQKLTDRLKNLGANHVVTEEELRKPEMKSFFKDVPQPRLALNCVGGKSSTELLRHLAPGGTMVTYGGMAKQPVIASVSQLIFKDLKLRGFWLSQWKKDHSPVQGADPHTLRSHPPRPTHGPRLLRGPAAGLPVCPRSIHAALRVFKADSHHVT", "length": 388, "header": "tr|A0ABI0P1A6-1|A0ABI0P1A6_BOVIN Computationally mapped isoform of Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Bos taurus OX=9913 GN=MECR PE=3 SV=1 CANONICAL=A0ABI0NYC3-1" }, "locus": { "chromosome": "2", "start_pos": 124368424, "end_pos": 124332554, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137700.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137700.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104109.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104109.1" } ] } }, { "isoform_ac": "F1MEY2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3/entry#F1MEY2-1", "sequence": { "sequence": "MWVCGALCRTRAPAQLGQRLLPESRRRRPASASFSASAEPSRVRALVYGHHGDPAKVVELKNLELAAVGGSDVHVKMLAAPINPSDINMIQGNYGLLPQLPAVGGNEGVGQVVAVGSGVTGVKPGDWVIPANPGLGTWRTEAVFGEEELITVPSDIPLQSAATLGVNPCTAYRMLVDFERLRPGDSIIQNASNSGVGQAVIQIAAARGLRTINVLRDRPDLQKLTDRLKNLGANHVVTEEELRKPEMKSFFKDVPQPRLALNCVGGKSSTELLRHLAPGGTMVTYGGMAKQPVIASVSQLIFKDLKLRGFWLSQWKKDHSPGADSGEDCRERQPSKENKLWNQPAWAQILLPPSLAVGSAEPSFGTSDQFKELILTLCDLIRRGQLTAPACSEVPLQDYLCALEASTQPFVSSKQILTM", "length": 419, "header": "tr|F1MEY2-1|A0ABI0NYC3_BOVIN Computationally mapped isoform of Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Bos taurus OX=9913 GN=MECR PE=3 SV=4 CANONICAL=A0ABI0NYC3-1" }, "locus": { "chromosome": "2", "start_pos": 124368419, "end_pos": 124332599, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022932.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022932.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022932.6", "url": "https://www.ensembl.org/id/ENSBTAP00000022932.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-77346", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77346", "resource": "Reactome", "description": "Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYC3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3" } ], "pmid": "" }, { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYC3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "enoyl-[acyl-carrier-protein] reductase (NADPH) activity", "id": "GO:0141148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141148", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYC3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYC3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22564", "name": "", "equation": "a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "22564", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22564" } ] }, { "id": "41812", "name": "", "equation": "(2E)-butenoyl-[ACP] + NADPH + H(+) = butanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "41812", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41812" } ] }, { "id": "41832", "name": "", "equation": "(2E)-hexenoyl-[ACP] + NADPH + H(+) = hexanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "41832", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41832" } ] }, { "id": "41848", "name": "", "equation": "(2E)-octenoyl-[ACP] + NADPH + H(+) = octanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "41848", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41848" } ] }, { "id": "41864", "name": "", "equation": "(2E)-decenoyl-[ACP] + NADPH + H(+) = decanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "41864", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41864" } ] }, { "id": "41880", "name": "", "equation": "(2E)-dodecenoyl-[ACP] + NADPH + H(+) = dodecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "41880", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41880" } ] }, { "id": "41896", "name": "", "equation": "(2E)-tetradecenoyl-[ACP] + NADPH + H(+) = tetradecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "41896", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41896" } ] }, { "id": "41912", "name": "", "equation": "(2E)-hexadecenoyl-[ACP] + NADPH + H(+) = hexadecanoyl-[ACP] + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NT64-1", "Q71SP7-1", "Q7YS70-1", "A0ABI0NYC3-1" ], "evidence": [ { "id": "41912", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41912" } ] }, { "id": "R-BTA-8952873", "name": "MECR dimer reduces tdec2-CoA to DEC-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-77308" ], "enzyme_list": [ "A0ABI0NYC3-1" ], "evidence": [ { "id": "R-BTA-8952873", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8952873" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-77308", "participant_name": "DEC-CoA [mitochondrial matrix]", "crossref": [ { "id": "61430", "database": "ChEBI", "url": "" }, { "id": "C05274", "database": "COMPOUND", "url": "" }, { "id": "ZINC000096014554", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0ABI0NT64", "gene_name": "FASN", "activity": [ { "ec_number": "1.1.1.100", "activity": "a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+).", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "1.3.1.39", "activity": "a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+).", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.38", "activity": "holo-[ACP] + acetyl-CoA = acetyl-[ACP] + CoA.", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.39", "activity": "holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA.", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.41", "activity": "a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2.", "evidence": [ { "id": "A0ABI0NT64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT64" } ] }, { "ec_number": "2.3.1.85", "activity": "acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H(+) = a 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPISEHN", "url": "https://omabrowser.org/oma/group/IPISEHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23268", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23268", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23268:SF101", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23268:SF101", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9RW35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RW35-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXR4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXR4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P009", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P009", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P009-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P009-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKL1", "url": "https://www.uniprot.org/uniprotkb/E1BKL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKL1-1", "url": 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105717055, "end_pos": 105715956, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123101.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123101.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077619.2", "url": "https://www.ensembl.org/id/ENSBTAP00000077619.2" } ] } }, { "isoform_ac": "A0ABI0NXR4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXR4/entry#A0ABI0NXR4-1", "sequence": { "sequence": "MLQSGNRRVSTLHHSPQEPCLQPAAVLGPDAAMGSRLLCCVTLCLLGAGLVDSEVTQTPKYLIKSRKQQVTLRCSPESGHRYVSWYQQALGQGPQFLILYYDGKVRTKGNMPDRFSGEQFGDSRSQMNLSSLELTDSAVYLCAGRQDTVLHDKEPLGQKHSC", "length": 162, "header": "tr|A0ABI0NXR4-1|A0ABI0NXR4_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC107132437 PE=4 SV=1 CANONICAL=A0ABI0NXR4-1" }, "locus": { "chromosome": "4", "start_pos": 105717055, "end_pos": 105716437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146707.1", "url": 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beta variable 5-5", "gene_name": "TRBV5-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPGLLCWVLLCLLGAGPVDAGVTQSPTHLIKTRGQQVTLRCSPISGHKSVSWYQQVLGQGPQFIFQYYEKEERGRGNFPDRFSARQFPNYSSELNVNALLLGDSALYLCASSL", "length": 114 }, "evidence": [ { "id": "A0ABI0NXR4", "url": "https://omabrowser.org/oma/group/A0ABI0NXR4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A8I6A233-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063691", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TGTGKLCETLTRCPSSPGSAHSGVVQSPRHIIKEKGGRSILKCIPISEHNNVAWYQQTHGQELKFLIQHYEKSEREKGNLPSRFSVQQFDDYHSEMNMSALELEDSAMYFCASSLHSLTELLAFCNLIFLFQLVIYQRGVGWCHKTIPKAQKCF", "length": 154 }, "evidence": [ { "id": "A0ABI0NXR4", "url": "https://omabrowser.org/oma/group/A0ABI0NXR4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXR4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXR4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXR4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXR4" } ], "pmid": "" }, { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXR4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXR4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NXR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXR4" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 142, "start_aa": "Ser", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NZX6-1", "uniprot_ac": "A0ABI0NZX6", "uniprot_id": "A0ABI0NZX6_BOVIN", "mass": { "chemical_mass": 52352.0, "monoisotopic_mass": 52352.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC78", "type": "recommended", "evidence": [ { "id": "A0ABI0NZX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX6" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 78", "type": "synonym", "evidence": [ { "id": "A0ABI0NZX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZX6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC78", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX6", "locus": { "chromosome": "25", "start_pos": 620318, "end_pos": 625047, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002470", "url": "https://www.ensembl.org/id/ENSBTAG00000002470" } ] } } ], "crossref": [ { "id": "ENSBTAG00000002470", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002470", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR029329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511835", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511835", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WAGTSKK", "url": "https://omabrowser.org/oma/group/WAGTSKK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BNT9", "url": "https://www.orthodb.org/?gene=E1BNT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22106:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22106:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NLP5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLP5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZX6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZX6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNT9", "url": "https://www.uniprot.org/uniprotkb/E1BNT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNT9-1", "url": "https://www.uniprot.org/uniprotkb/E1BNT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEHGAAPVPPPRATENVLPRAEAWLPGVPGGAPAWATNLGTELPSDLELSEEQRLQVGVGLLGAGRREGIPRASQTHPDQPQVCKELVDLQIKNQRLQEQHDAEIFELKSEVLWLESRMLELELQGVQAAPAEADPRHHLALAQELGHKPGGQGHSYRHRLQAQSADFLTPENKQQELGDGTGVQPPSLKLPAEAKRVQEQHGAQQKALETCVAALGQQLQGAWEEARTAGQRLAAQAVVLSSCRGQLHQAEAENAQLQLQLKKLNEAYAIRLQHCAQTVAGYADGAGPKPTAAALRTFLETTLEDIRTAHHSREQQLARAARFYRKCLADLSRRHEELLTAHRAQGTPRAAFGAAPSDVALLPLSTVTESSHQTEDQARLEKELQKLKAQKGSSEVSQGGTVEPQGLEAASWAQIRQNLQEFARGTQSWSGSGHSCWSAPRWQRSSFLSYRSTWTSTWEGGPGIRGPRFQALAAGLVHN", "length": 480, "header": "tr|A0ABI0NZX6-1|A0ABI0NZX6_BOVIN Isoform 1 of Coiled-coil domain containing 78 OS=Bos taurus OX=9913 GN=CCDC78 PE=4 SV=1 CANONICAL=A0ABI0NZX6-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NLP5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX6/entry#A0ABI0NLP5-1", "sequence": { "sequence": "MEHGAAPVPPPRATENVLPRAEAWLPGVPGGAPAWATNLGTELPSDLELSEEQRLQVGVGLLGAGRREGIPRASQTHPDQPQVCKELVDLQIKNQRLQEQHDAEIFELKSEVLWLESRMLELELQGVQAAPAEADPRHHLALAQELGHKPGGQGHSYRHRLQAQSADFLTPENKQQELGDGTGVQPPSLKLPAEAKRVQEQHGAQQKALETCVAALGQQLQGAWEEARTAGQRLAAQAVVLSSCRGQLHQAEAENAQLQLQLKKLNEAYAIRLQHCAQTVAGYADGAGPKPTAAALRTFLETTLEDIRTAHHSREQQLARAARFYRKCLADLSRRHEELLTAHRAQGTPRAAFGAAPSDVALLPLSTVTESSHQTEDQARLEKELQKLKAQKGSSEVSQGGTVEPQGLEAASWAQIRQNLQEFARGTQSWSGSGHSCWSAPRWQRSSFLSYRSTWTSTWEGTSRRS", "length": 466, "header": "tr|A0ABI0NLP5-1|A0ABI0NZX6_BOVIN Computationally mapped isoform of Coiled-coil domain containing 78 OS=Bos taurus OX=9913 GN=CCDC78 PE=4 SV=1 CANONICAL=A0ABI0NZX6-1" }, "locus": { "chromosome": "25", "start_pos": 624848, "end_pos": 621414, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150150.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150150.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106057.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106057.1" } ] } }, { "isoform_ac": "A0ABI0NZX6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX6/entry#A0ABI0NZX6-1", "sequence": { "sequence": "MEHGAAPVPPPRATENVLPRAEAWLPGVPGGAPAWATNLGTELPSDLELSEEQRLQVGVGLLGAGRREGIPRASQTHPDQPQVCKELVDLQIKNQRLQEQHDAEIFELKSEVLWLESRMLELELQGVQAAPAEADPRHHLALAQELGHKPGGQGHSYRHRLQAQSADFLTPENKQQELGDGTGVQPPSLKLPAEAKRVQEQHGAQQKALETCVAALGQQLQGAWEEARTAGQRLAAQAVVLSSCRGQLHQAEAENAQLQLQLKKLNEAYAIRLQHCAQTVAGYADGAGPKPTAAALRTFLETTLEDIRTAHHSREQQLARAARFYRKCLADLSRRHEELLTAHRAQGTPRAAFGAAPSDVALLPLSTVTESSHQTEDQARLEKELQKLKAQKGSSEVSQGGTVEPQGLEAASWAQIRQNLQEFARGTQSWSGSGHSCWSAPRWQRSSFLSYRSTWTSTWEGGPGIRGPRFQALAAGLVHN", "length": 480, "header": "tr|A0ABI0NZX6-1|A0ABI0NZX6_BOVIN Isoform 1 of Coiled-coil domain containing 78 OS=Bos taurus OX=9913 GN=CCDC78 PE=4 SV=1 CANONICAL=A0ABI0NZX6-1" }, "locus": { "chromosome": "25", "start_pos": 624848, "end_pos": 621464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136782.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136782.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106912.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106912.1" } ] } }, { "isoform_ac": "E1BNT9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX6/entry#E1BNT9-1", "sequence": { "sequence": "MEHGAAPVPPPRATENVLPRAEAWLPGVPGGAPAWATNLGTELPSDLELSEEQRLQVCKELVDLQIKNQRLQEQHDAEIFELKSEVLWLESRMLELELQGVQAAPAEADPRHHLALAQELGHKPGGQGHSYRHRLQAQSADFLTPENKQQELGDGTGVQPPSLKLPAEAKRVQEQHGAQQKALETCVAALGQQLQGAWEEARTAGQRLAAQAVVLSSCRGQLHQAEAENAQLQLQLKKLNEAYAIRLQHCAQTVAGYADGAGPKPTAAALRTFLETTLEDIRTAHHSREQQLARAARFYRKCLADLSRRHEELLTAHRAQGTPRAAFGAAPSDVALLPLSTVTESSHQTEDQARLEKELQKLKAQKGSSEVSQGGTVEPQGLEAASWAQIRQNLQEFARGTQSWSGSGHSCWSAPRWQRSSFLSYRSTWTSTWEGTSRRS", "length": 440, "header": "tr|E1BNT9-1|A0ABI0NZX6_BOVIN Computationally mapped isoform of Coiled-coil domain containing 78 OS=Bos taurus OX=9913 GN=CCDC78 PE=4 SV=3 CANONICAL=A0ABI0NZX6-1" }, "locus": { "chromosome": "25", "start_pos": 624848, "end_pos": 621414, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003211.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003211.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003211.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003211.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 292, "start_aa": "Thr", "end_pos": 292, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr292", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:511835", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511835", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z6B2-1", "protein_name": "Coiled-coil domain containing 78", "gene_name": "CCDC78", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDFGSVADKENANALMEQAQHLANKNVQLQDRNERLYAGFGDVQERMGRLAGSKPDLSPRTIFSEEEKLKISKELVDLQIETNKMKEQYETEKFELKNMILALENRVLELELRSEKVSRERDALRDQLHALETSRKELADEYIILKSNYLALGKELDQEVLKNEELSLELLSLTNARSTESNHHHSHASATEPAAEPDRVRVTLHHPPAQKVKPEVVAAPEHEWQKPGRNLLGNQDHIKEEIEKLKQTYDSQQQKLEEKVIAMGKELQEAKKAVCDPQQKLAEQSAVLLACQSQLQEVEAENSRLQLRLKELSEEYRCRLTQYIRDVAEYMDSKPSTRTGPGKAPAEHADMKRFVDNMLKDIRASYKAREEQLAGAARSYKKRMKSLAKKHENLLIAYSVQREKILSLGSSEMDSGPAELHFAITDPELLTNTTQELNRLRENKAKLEMQLHELQKKRLKETSGFQLSPDQKRDEEGWAEVRKQLQEFTHTTQEDLEKERSQLLTRAIVAEEQVLELQDYIEKHLARYRQEVLRVRKLAGGEEPRAHSAGAADAHSLPRSRRAVSREL", "length": 568 }, "evidence": [ { "id": "A0ABI0NZX6", "url": "https://omabrowser.org/oma/group/A0ABI0NZX6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2IDD5-1", "protein_name": "Coiled-coil domain-containing protein 78", "gene_name": "CCDC78", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEHAATTGPRPGPPSRRVENVVLRAKDWLPGAPGGTAVWATSLEAEVPPDLALNKEQQLQISKELVDIQITTHHLHEQHEAEIFQLKSEILRLESRVLELELRGDGTSQGCAVPVESDPRHPRAAAQELRHKAQVPGHSDDHRFQVQPKNTMNPENEQHRLGSGLQGEVKWALEHQEARQQALVTRVATLGRQLQGAREEARAAGQRLATQAVVLCSCQGQLRQAEAENARLQLQLKKLKDEYVLRLQHCAWQAVEHADGAGQAPATTALRTFLEATLEDIRAAHRSREQQLARAARSYHKRLVDLSRRHEELLVAYRAPGNPQAIFDIASLDLEPLPVPLVTDFSHREDQHGGPGALLSSPKKRPGGASQGGTSEPQGLDAASWAQIHQKLRDFSRSTQSWNGSGHSCWSGPRWLKSNFLSYRSTWTSTWAGTSTKS", "length": 438 }, "evidence": [ { "id": "A0ABI0NZX6", "url": "https://omabrowser.org/oma/group/A0ABI0NZX6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3Z5T1-1", "protein_name": "Coiled-coil domain-containing protein 78", "gene_name": "Ccdc78", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQRPELLSSMEYVASPDPKPGVPLRVAENVAPGAEDWLPSASGHLAWATSLETEHQTHLELSEEQRLQISKELVDLQIATHHLREQHEAEVFELRREILRLESRVLELELHGNGACQGHKVQPMANLGQHQVPPLEPPGGQQKLQEELKWLLEHHRARQQALETQVGVLSQQLQGAREEARTTGQQLASQAMVLASCKGQLRQAEAENTQLQLQLKKMNEEYAVRLQHYARETVENASSTNQAALQAFLESTLQDIRAAHRTREQQLAQAARTYRKRLADLNQRQELLLTTCRATFATAINLEPLPMHWATELSHPRENEYGRHRTLLLYPEKGSGETSKENKSQPLALDTASWAQIQQRLQDFSQDTQAELERERAQLMVRATMAEQQLSELQEYVDQHLGRYKQEILKLRKLVNIGDPQGVEAVSSPGSGGARL", "length": 437 }, "evidence": [ { "id": "A0ABI0NZX6", "url": "https://omabrowser.org/oma/group/A0ABI0NZX6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELZ7-1", "protein_name": "Coiled-coil domain containing 78", "gene_name": "Ccdc78", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLQFSLRQDRQSLRSTEALATLTTLPVTARKQATIRRIRGQGFLEDSIASMEYRAAPDPRPWASLQVAENVVPGAEDWLPRVSGNPARATSLETEPQTHLELSEEQRLQISKELVDLQIATHHLREQHEAEVFELRREVLRLESRVLELEMHGTGACQGQTVQPAANPGQYQVSPQEPSGGQQRLQEELKWVLEHHRVRQQALETQVGALSRQLQGAREEARTAGQQLAAQAMVLSSCKDQLRQAEAENAQLQLQLKKLNEEYAVRLQRYAKETAETSSSTNQASLQAFLEAALQDIRAAHRSREQQLAQAARAYRKRLADLNQRQELLLTTCRATFATAINLEPSPLHWAAELSHPRENEYGPHRTTLLLYPEKGSGEASKEDKSQPLALDTASWVQIQQKLQDFSQDTQAELERERAQLMVRATMAEQQLSELQEYVDQHLGRYKQEILKLRKLANSGDSQGVESMPSTRPRRPRTQSH", "length": 481 }, "evidence": [ { "id": "A0ABI0NZX6", "url": "https://omabrowser.org/oma/group/A0ABI0NZX6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZX6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NZX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX6" }, { "id": "PF14739", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14739" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4472", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 181, "start_aa": "Gln", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 292 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NW42-1", "uniprot_ac": "A0ABI0NW42", "uniprot_id": "A0ABI0NW42_BOVIN", "mass": { "chemical_mass": 24728.0, "monoisotopic_mass": 24728.0 }, "refseq": {}, "gene_names": [ { "name": "TEX35", "type": "recommended", "evidence": [ { "id": "A0ABI0NW42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW42" } ] } ], "protein_names": [ { "name": "Testis expressed 35", "type": "synonym", "evidence": [ { "id": "A0ABI0NW42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW42/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW42" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TEX35", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW42", "locus": { "chromosome": "16", "start_pos": 59925320, "end_pos": 59915002, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004941", "url": "https://www.ensembl.org/id/ENSBTAG00000004941" } ] } } ], "crossref": [ { "id": "ENSBTAG00000004941", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004941", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR027874", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027874", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GIMDKDF", "url": "https://omabrowser.org/oma/group/GIMDKDF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MB56", "url": "https://www.orthodb.org/?gene=F1MB56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36860:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36860:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NW42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NW42-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MB56", "url": "https://www.uniprot.org/uniprotkb/F1MB56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MB56-1", "url": "https://www.uniprot.org/uniprotkb/F1MB56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAKRVEPKKTSLSKNYRAVCLELKPEPIKTYDYKGAKQEGPFTKPGGTKELKNELREVREELKEKMEEIKQIKDVMDKDFDKLQEFVEIMKEMQKDMDEKMDVLINIQKNSKFPLRRGLKMQQELRLIGKTDTEPQLRLRKMDGAGGAPLSLHKKMVARQQPKDPMDPLHQCDSCFETSIPRLGILLTLGVWTCFLIYLYFNSCVTEDIVPT", "length": 213, "header": "tr|A0ABI0NW42-1|A0ABI0NW42_BOVIN Isoform 1 of Testis expressed 35 OS=Bos taurus OX=9913 GN=TEX35 PE=4 SV=1 CANONICAL=A0ABI0NW42-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NW42-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW42/entry#A0ABI0NW42-1", "sequence": { "sequence": "MSAKRVEPKKTSLSKNYRAVCLELKPEPIKTYDYKGAKQEGPFTKPGGTKELKNELREVREELKEKMEEIKQIKDVMDKDFDKLQEFVEIMKEMQKDMDEKMDVLINIQKNSKFPLRRGLKMQQELRLIGKTDTEPQLRLRKMDGAGGAPLSLHKKMVARQQPKDPMDPLHQCDSCFETSIPRLGILLTLGVWTCFLIYLYFNSCVTEDIVPT", "length": 213, "header": "tr|A0ABI0NW42-1|A0ABI0NW42_BOVIN Isoform 1 of Testis expressed 35 OS=Bos taurus OX=9913 GN=TEX35 PE=4 SV=1 CANONICAL=A0ABI0NW42-1" }, "locus": { "chromosome": "16", "start_pos": 59925188, "end_pos": 59915087, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152656.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152656.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105085.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105085.1" } ] } }, { "isoform_ac": "F1MB56-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW42/entry#F1MB56-1", "sequence": { "sequence": "MSAKRVEPKKTSLSKNYRAVCLELKPEPIKTYDYKGAKQEGPFTKPGGTKELKNELREVREELKEKMEEIKQIKDVMDKDFDKLQEFVEIMKEMQKDMDEKMDVLINIQKNSKFPLRRGLKMQQELRLIGKTDTEPQLRLRKMDGAGGAPLSLHKKMVARQQPKDPMDPLHQCDSCFEKCLLCTPQNNYDRGKLPYHAWASFSPLASGPAF", "length": 211, "header": "tr|F1MB56-1|A0ABI0NW42_BOVIN Computationally mapped isoform of Testis expressed 35 OS=Bos taurus OX=9913 GN=TEX35 PE=4 SV=1 CANONICAL=A0ABI0NW42-1" }, "locus": { "chromosome": "16", "start_pos": 59925138, "end_pos": 59915087, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006500.4", "url": "https://www.ensembl.org/id/ENSBTAT00000006500.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006500.3", "url": "https://www.ensembl.org/id/ENSBTAP00000006500.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q14BK3-1", "protein_name": "Testis-expressed protein 35", "gene_name": "Tex35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAKNAELKKTNLKKNYKAVCMEPKLTQIYDFKGFKQEGLLIRKGMTRELKNELREVREQLTEKMEEIKQIKDIMDKDFDKLYEFVEIMKEMQQDMDEKMDVLINNQKNNKLPFQNQAKEQQKFWQLGKMDKSSQAMITEEPDGVPLACDKNVVPPKPTRNPLESLHPCQSCCEKCLLCALKTNRNQGRPSHHAWVPFSPLSSGAAF", "length": 207 }, "evidence": [ { "id": "A0ABI0NW42", "url": "https://omabrowser.org/oma/group/A0ABI0NW42/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5T0J7-1", "protein_name": "Testis-expressed protein 35", "gene_name": "TEX35", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAKRAELKKTHLSKNYKAVCLELKPEPTKTFDYKAVKQEGRFTKAGVTQDLKNELREVREELKEKMEEIKQIKDLMDKDFDKLHEFVEIMKEMQKDMDEKMDILINTQKNYKLPLRRAPKEQQELRLMGKTHREPQLRPKKMDGASGVNGAPCALHKKTMAPQKTKQGSLDPLHHCGTCCEKCLLCALKNNYNRGNIPSEASGLYKGGEEPVTTQPSVGHAVPAPKSQTEGR", "length": 233 }, "evidence": [ { "id": "A0ABI0NW42", "url": "https://omabrowser.org/oma/group/A0ABI0NW42/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NVX7-1", "uniprot_ac": "A0ABI0NVX7", "uniprot_id": "A0ABI0NVX7_BOVIN", "mass": { "chemical_mass": 23449.0, "monoisotopic_mass": 23449.0 }, "refseq": {}, "gene_names": [ { "name": "KXD1", "type": "recommended", "evidence": [ { "id": "A0ABI0NVX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVX7" } ] } ], "protein_names": [ { "name": "KxDL motif-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0ABI0NVX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVX7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVX7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVX7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KXD1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVX7", "locus": { "chromosome": "7", "start_pos": 4607363, "end_pos": 4614956, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010545", "url": "https://www.ensembl.org/id/ENSBTAG00000010545" } ] } } ], "crossref": [ { "id": "ENSBTAG00000010545", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010545", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR019371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MN50", "url": "https://www.orthodb.org/?gene=F1MN50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13511", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13511", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13511:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13511:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NVX7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVX7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P080", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P080", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P080-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P080-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MN50", "url": "https://www.uniprot.org/uniprotkb/F1MN50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MN50-1", "url": "https://www.uniprot.org/uniprotkb/F1MN50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCRCYCQRRPGRVLGRDETVEPFKKAAEEEEEMDPPDSASRVFCSRILSMVNADDVSAIILAQKNMLDRFEKTNEMLLNFNNLSSARLQQMNERFLHHTRTLVEMKRDLDSIFRRIRTLKGKLARQHPEAFSHIPEASLLEDEDEDPIPPSTTTTIATSEQSTGSCDTSPDTVSPSLSPGFEDLSHIRPGSPAINGRSHTDDEEMPGE", "length": 208, "header": "tr|A0ABI0NVX7-1|A0ABI0NVX7_BOVIN Isoform 1 of KxDL motif-containing protein 1 OS=Bos taurus OX=9913 GN=KXD1 PE=3 SV=1 CANONICAL=A0ABI0NVX7-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NVX7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVX7/entry#A0ABI0NVX7-1", "sequence": { "sequence": "MCRCYCQRRPGRVLGRDETVEPFKKAAEEEEEMDPPDSASRVFCSRILSMVNADDVSAIILAQKNMLDRFEKTNEMLLNFNNLSSARLQQMNERFLHHTRTLVEMKRDLDSIFRRIRTLKGKLARQHPEAFSHIPEASLLEDEDEDPIPPSTTTTIATSEQSTGSCDTSPDTVSPSLSPGFEDLSHIRPGSPAINGRSHTDDEEMPGE", "length": 208, "header": "tr|A0ABI0NVX7-1|A0ABI0NVX7_BOVIN Isoform 1 of KxDL motif-containing protein 1 OS=Bos taurus OX=9913 GN=KXD1 PE=3 SV=1 CANONICAL=A0ABI0NVX7-1" }, "locus": { "chromosome": "7", "start_pos": 4614808, "end_pos": 4608091, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144258.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144258.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105019.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105019.1" } ] } }, { "isoform_ac": "A0ABI0P080-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVX7/entry#A0ABI0P080-1", "sequence": { "sequence": "MCRPKILSSCLFQAAEEEEEMDPPDSASRVFCSRILSMVNADDVSAIILAQKNMLDRFEKTNEMLLNFNNLSSARLQQMNERFLHHTRTLVEMKRDLDSIFRRIRTLKGKLARQHPEAFSHIPEASLLEDEDEDPIPPSTTTTIATSEQSTGSCDTSPDTVSPSLSPGFEDLSHIRPGSPAINGRSHTDDEEMPGE", "length": 196, "header": "tr|A0ABI0P080-1|A0ABI0P080_BOVIN Computationally mapped isoform of KxDL motif-containing protein 1 OS=Bos taurus OX=9913 GN=KXD1 PE=3 SV=1 CANONICAL=A0ABI0NVX7-1" }, "locus": { "chromosome": "7", "start_pos": 4614808, "end_pos": 4608091, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147925.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147925.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104205.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104205.1" } ] } }, { "isoform_ac": "F1MN50-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVX7/entry#F1MN50-1", "sequence": { "sequence": "MGHLITKIISGRDETVEPFKKAAEEEEEMDPPDSASRVFCSRILSMVNADDVSAIILAQKNMLDRFEKTNEMLLNFNNLSSARLQQMNERFLHHTRTLVEMKRDLDSIFRRIRTLKGKLARQHPEAFSHIPEASLLEDEDEDPIPPSTTTTIATSEQSTGSCDTSPDTVSPSLSPGFEDLSHIRPGSPAINGRSHTDDEEMPGE", "length": 204, "header": "tr|F1MN50-1|A0ABI0NVX7_BOVIN Computationally mapped isoform of KxDL motif-containing protein 1 OS=Bos taurus OX=9913 GN=KXD1 PE=3 SV=3 CANONICAL=A0ABI0NVX7-1" }, "locus": { "chromosome": "7", "start_pos": 4612729, "end_pos": 4608091, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013943.8", "url": "https://www.ensembl.org/id/ENSBTAT00000013943.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013943.6", "url": "https://www.ensembl.org/id/ENSBTAP00000013943.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NVX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVX7" }, { "id": "PF10241", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10241" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KxDL", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 131, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NVE2-1", "uniprot_ac": "A0ABI0NVE2", "uniprot_id": "A0ABI0NVE2_BOVIN", "mass": { "chemical_mass": 51898.0, "monoisotopic_mass": 51898.0 }, "refseq": {}, "gene_names": [ { "name": "NOL4L", "type": "recommended", "evidence": [ { "id": "A0ABI0NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE2" } ] } ], "protein_names": [ { "name": "Nucleolar protein 4 like", "type": "synonym", "evidence": [ { "id": "A0ABI0NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVE2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NOL4L", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE2", "locus": { "chromosome": "13", "start_pos": 61877708, "end_pos": 62005799, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008348", "url": "https://www.ensembl.org/id/ENSBTAG00000008348" } ] } } ], "crossref": [ { "id": "ENSBTAG00000008348", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008348", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "785034", "url": "https://www.ncbi.nlm.nih.gov/gene/785034", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12449", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12449", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12449:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12449:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NLD8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLD8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NP17", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NP17-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVE2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVE2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0Q3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P465", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P465", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P465-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P465-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MPV8", "url": "https://www.uniprot.org/uniprotkb/F1MPV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MPV8-1", "url": "https://www.uniprot.org/uniprotkb/F1MPV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY80", "url": "https://www.uniprot.org/uniprotkb/G3MY80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY80-1", "url": "https://www.uniprot.org/uniprotkb/G3MY80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGKGGLGSLLLDETSVSSEDFDMNDSTWMSADPHLASSLSPSQDERMRSPQNLHSQEDDDSSSESGSGNGSSTLNPSTSSSTQGDPAFPEMNGNGTVAPMDFTASAEDQPINLCDKLPQGSTLGTPSYPSDGCGADGLRSRVKYGVKTTPESPPYSSGSYDSIKTEVSGCPEDLTVGRAPTADDDDDDHDDHEDNDKMNDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQSSQDEPVALDKQHSRDPTAITHSTYSLPASYSQDPVYVNGGLNYSYRGYGALGSNLQPPASLQTGNHSNGALCNSSQVTDADRTQISVGEKQPPKDTNLPMEPGAALSGGLGPFHTEAWGWERLGKNNGPVESSLGAGKDGWGRSWGFLGQAFGFCSMCGGSHR", "length": 480, "header": "tr|A0ABI0NVE2-1|A0ABI0NVE2_BOVIN Isoform 1 of Nucleolar protein 4 like OS=Bos taurus OX=9913 GN=NOL4L PE=4 SV=1 CANONICAL=A0ABI0NVE2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NLD8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE2/entry#A0ABI0NLD8-1", "sequence": { "sequence": "MNDSTWMSADPHLASSLSPSQDERMRSPQNLHSQEDDDSSSESGSGNGSSTLNPSTSSSTQGDPAFPEMNGNGTVAPMDFTASAEDQPINLCDKLPQGSTLGTPSYPSDGCGADGLRSRVKYGVKTTPESPPYSSGSYDSIKTEVSGCPEDLTVGRAPTADDDDDDHDDHEDNDKMNDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQSSQDEPVALDKQHSRDPTAITHSTYSLPASYSQDPVYVNGGLNYSYRGYGALGSNLQPPASLQTGNHSNGRSTVQQPCCVGTRLEWVQRRSCGREVKSPCRARGEPFSGGRRWWAHGPQHERRGLHHLHHAHAHPLQQQHQPDHAHCPAQPHRDQRRAAAHRRLPRVRRLPAALGR", "length": 469, "header": "tr|A0ABI0NLD8-1|A0ABI0NVE2_BOVIN Computationally mapped isoform of Nucleolar protein 4 like OS=Bos taurus OX=9913 GN=NOL4L PE=4 SV=1 CANONICAL=A0ABI0NVE2-1" }, "locus": { "chromosome": "13", "start_pos": 61902023, "end_pos": 61878743, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142643.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142643.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105841.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105841.1" } ] } }, { "isoform_ac": "A0ABI0NP17-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE2/entry#A0ABI0NP17-1", "sequence": { "sequence": "MNDSTWMSADPHLASSLSPSQDERMRSPQNLHSQEDDDSSSESGSGNGSSTLNPSTSSSTQGDPAFPEMNGNGTVAPMDFTASAEDQPINLCDKLPQGSTLGTPSYPSDGCGADGLRSRVKYGVKTTPESPPYSSGSYDSIKTEVSGCPEDLTVGRAPTADDDDDDHDDHEDNDKMNDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQSSQDEPVALDKQHSRDPTAITHSTYSLPASYSQDPVYVNGGLNYSYRGYGALGSNLQPPASLQTGNHSNGLVPRSPALMAEPGFSPRAHGPQHERRGLHHLHHAHAHPLQQQHQPDHAHCPAQPHRDQRRAAAHRRLPRVRRLPAALGR", "length": 442, "header": "tr|A0ABI0NP17-1|A0ABI0NVE2_BOVIN Computationally mapped isoform of Nucleolar protein 4 like OS=Bos taurus OX=9913 GN=NOL4L PE=4 SV=1 CANONICAL=A0ABI0NVE2-1" }, "locus": { "chromosome": "13", "start_pos": 61902023, "end_pos": 61878743, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136859.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136859.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107555.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107555.1" } ] } }, { "isoform_ac": "A0ABI0NVE2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE2/entry#A0ABI0NVE2-1", "sequence": { "sequence": "MDGKGGLGSLLLDETSVSSEDFDMNDSTWMSADPHLASSLSPSQDERMRSPQNLHSQEDDDSSSESGSGNGSSTLNPSTSSSTQGDPAFPEMNGNGTVAPMDFTASAEDQPINLCDKLPQGSTLGTPSYPSDGCGADGLRSRVKYGVKTTPESPPYSSGSYDSIKTEVSGCPEDLTVGRAPTADDDDDDHDDHEDNDKMNDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQSSQDEPVALDKQHSRDPTAITHSTYSLPASYSQDPVYVNGGLNYSYRGYGALGSNLQPPASLQTGNHSNGALCNSSQVTDADRTQISVGEKQPPKDTNLPMEPGAALSGGLGPFHTEAWGWERLGKNNGPVESSLGAGKDGWGRSWGFLGQAFGFCSMCGGSHR", "length": 480, "header": "tr|A0ABI0NVE2-1|A0ABI0NVE2_BOVIN Isoform 1 of Nucleolar protein 4 like OS=Bos taurus OX=9913 GN=NOL4L PE=4 SV=1 CANONICAL=A0ABI0NVE2-1" }, "locus": { "chromosome": "13", "start_pos": 61906340, "end_pos": 61881484, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152796.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152796.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104224.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104224.1" } ] } }, { "isoform_ac": "A0ABI0P0Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE2/entry#A0ABI0P0Q3-1", "sequence": { "sequence": "MNDSTWMSADPHLASSLSPSQDERMRSPQNLHSQEDDDSSSESGSGNGSSTLNPSTSSSTQGDPAFPEMNGNGTVAPMDFTASAEDQPINLCDKLPQGSTLGTPSYPSDGCGADGLRSRVKYGVKTTPESPPYSSGSYDSIKTEVSGCPEDLTVGRAPTADDDDDDHDDHEDNDKMNDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQSSQDEPVALDKQHSRDPTAITHSTYSLPASYSQDPVYVNGGLNYSYRGYGALGSNLQPPASLQTGNHSNGALCNSSQVTDADRTQISVGEKQPPKDTNLPMEPGPTDLSMKGGASTTSTTPTPTPSNNSTSRTMPTAQLSPTEISAVRQLIAGYRESAAFLLRSADELENLILQQN", "length": 469, "header": "tr|A0ABI0P0Q3-1|A0ABI0P0Q3_BOVIN Computationally mapped isoform of Nucleolar protein 4 like OS=Bos taurus OX=9913 GN=NOL4L PE=4 SV=1 CANONICAL=A0ABI0NVE2-1" }, "locus": { "chromosome": "13", "start_pos": 61902023, "end_pos": 61878712, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142695.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142695.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104408.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104408.1" } ] } }, { "isoform_ac": "A0ABI0P465-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE2/entry#A0ABI0P465-1", "sequence": { "sequence": "MLACPGMPVRTTQDDSSSESGSGNGSSTLNPSTSSSTQGDPAFPEMNGNGTVAPMDFTASAEDQPINLCDKLPQGSTLGTPSYPSDGCGADGLRSRVKYGVKTTPESPPYSSGSYDSIKTEVSGCPEDLTVGRAPTADDDDDDHDDHEDNDKMNDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQSSQDEPVALDKQHSRDPTAITHSTYSLPASYSQDPVYVNGGLNYSYRGYGALGSNLQPPASLQTGNHSNGPTDLSMKGGASTTSTTPTPTPSNNSTSRTMPTAQLSPTEISAVRQLIAGYRESAAFLLRSADELENLILQQN", "length": 412, "header": "tr|A0ABI0P465-1|A0ABI0P465_BOVIN Computationally mapped isoform of Nucleolar protein 4 like OS=Bos taurus OX=9913 GN=NOL4L PE=4 SV=1 CANONICAL=A0ABI0NVE2-1" }, "locus": { "chromosome": "13", "start_pos": 61886341, "end_pos": 61878712, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149234.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149234.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106320.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106320.1" } ] } }, { "isoform_ac": "F1MPV8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE2/entry#F1MPV8-1", "sequence": { "sequence": "MGGGDETSVSSEDFDMNDSTWMSADPHLASSLSPSQDERMRSPQNLHSQEDDDSSSESGSGNGSSTLNPSTSSSTQGDPAFPEMNGNGTVAPMDFTASAEDQPINLCDKLPQGSTLGTPSYPSDGCGADGLRSRVKYGVKTTPESPPYSSGSYDSIKTEVSGCPEDLTVGRAPTADDDDDDHDDHEDNDKMNDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQSSQDEPVALDKQHSRDPTAITHSTYSLPASYSQDPVYVNGGLNYSYRGYGALGSNLQPPASLQTGNHSNGPTDLSMKGGASTTSTTPTPTPSNNSTSRTMPTAQLSPTEISAVRQLIAGYRESAAFLLRSADELENLILQQN", "length": 450, "header": "tr|F1MPV8-1|A0ABI0NVE2_BOVIN Computationally mapped isoform of Nucleolar protein 4 like OS=Bos taurus OX=9913 GN=NOL4L PE=4 SV=5 CANONICAL=A0ABI0NVE2-1" }, "locus": { "chromosome": "13", "start_pos": 61902229, "end_pos": 61878712, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039299.7", "url": "https://www.ensembl.org/id/ENSBTAT00000039299.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000039097.7", "url": "https://www.ensembl.org/id/ENSBTAP00000039097.7" } ] } }, { "isoform_ac": "G3MY80-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE2/entry#G3MY80-1", "sequence": { "sequence": "MSFSADGPSPPVSLSTVSTRKAMTCPQDETSVSSEDFDMNDSTWMSADPHLASSLSPSQDERMRSPQNLHSQEDDDSSSESGSGNGSSTLNPSTSSSTQGDPAFPEMNGNGTVAPMDFTASAEDQPINLCDKLPQGSTLGTPSYPSDGCGADGLRSRVKYGVKTTPESPPYSSGSYDSIKTEVSGCPEDLTVGRAPTADDDDDDHDDHEDNDKMNDSEGMDPERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIESCSRQFPEFQERARKRIRTYLKSCRRMKKNGMEMTRPTPPHLTSAMAENILAAACESETRKAAKRMRLEIYQSSQDEPVALDKQHSRDPTAITHSTYSLPASYSQDPVYVNGGLNYSYRGYGALGSNLQPPASLQTGNHSNGPTDLSMKGGASTTSTTPTPTPSNNSTSRTMPTAQLSPTEISAVRQLIAGYRESAAFLLRSADELENLILQQN", "length": 473, "header": "tr|G3MY80-1|A0ABI0NVE2_BOVIN Computationally mapped isoform of Nucleolar protein 4 like OS=Bos taurus OX=9913 GN=NOL4L PE=4 SV=3 CANONICAL=A0ABI0NVE2-1" }, "locus": { "chromosome": "13", "start_pos": 61904172, "end_pos": 61878712, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065241.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065241.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054508.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054508.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE2" }, { "id": "PF23079", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23079" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleolar protein 4 helical", "eco_id": "ECO_0000259", "start_pos": 208, "end_pos": 302, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 25, "end_pos": 27 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 382, "end_pos": 384 }, { "start_pos": 390, "end_pos": 392 }, { "start_pos": 70, "end_pos": 72 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NZG9-1", "uniprot_ac": "A0ABI0NZG9", "uniprot_id": "A0ABI0NZG9_BOVIN", "mass": { "chemical_mass": 38509.0, "monoisotopic_mass": 38509.0 }, "refseq": { "ac": "NP_001192860", "name": "alpha-tocopherol transfer protein-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192860" }, "gene_names": [ { "name": "TTPAL", "type": "recommended", "evidence": [ { "id": "A0ABI0NZG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG9" } ] }, { "name": "TTPAL", "type": "synonym", "evidence": [ { "id": "NP_001192860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192860" } ] } ], "protein_names": [ { "name": "Alpha tocopherol transfer protein like", "type": "synonym", "evidence": [ { "id": "A0ABI0NZG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG9/entry#names_and_taxonomy" } ] }, { "name": "alpha-tocopherol transfer protein-like", "type": "synonym", "evidence": [ { "id": "NP_001192860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192860" } ] }, { "name": "tocopherol (alpha) transfer protein-like", "type": "synonym", "evidence": [ { "id": "NP_001192860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192860" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZG9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TTPAL", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG9", "locus": { "chromosome": "13", "start_pos": 72905729, "end_pos": 72891431, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018873", "url": "https://www.ensembl.org/id/ENSBTAG00000018873" } ] } } ], "crossref": [ { "id": "ENSBTAG00000018873", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018873", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "526582", "url": "https://www.ncbi.nlm.nih.gov/gene/526582", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:526582", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526582", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQCDDSM", "url": "https://omabrowser.org/oma/group/VQCDDSM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MTT2", "url": "https://www.orthodb.org/?gene=F1MTT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10174", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10174", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10174:SF130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10174:SF130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28528", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28528", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192860", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192860", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NZG9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZG9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZL8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZL8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MTT2", "url": "https://www.uniprot.org/uniprotkb/F1MTT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MTT2-1", "url": "https://www.uniprot.org/uniprotkb/F1MTT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEESDSLRTSPSVASLSENELPPPSAPAGYVCSLTEDLVAKAREELQEKPEWRLRDVQALRDMVRKECPNLSTSLEDAFLLRFLRARKFDYDRALQLLINYHSCRRSWPEVFNNLRPSALKEVLASGFLTVLPHTDPRGCHVLCLRPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRNILPREYGGTAGELDITAWNAVLLASEEDFVREFCQPGPPCDSILGQALPPEGLSSEVPCDDSMRAMKSQLYSCY", "length": 342, "header": "tr|A0ABI0NZG9-1|A0ABI0NZG9_BOVIN Isoform 1 of Alpha tocopherol transfer protein like OS=Bos taurus OX=9913 GN=TTPAL PE=4 SV=1 CANONICAL=A0ABI0NZG9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NZG9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG9/entry#A0ABI0NZG9-1", "sequence": { "sequence": "MSEESDSLRTSPSVASLSENELPPPSAPAGYVCSLTEDLVAKAREELQEKPEWRLRDVQALRDMVRKECPNLSTSLEDAFLLRFLRARKFDYDRALQLLINYHSCRRSWPEVFNNLRPSALKEVLASGFLTVLPHTDPRGCHVLCLRPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRNILPREYGGTAGELDITAWNAVLLASEEDFVREFCQPGPPCDSILGQALPPEGLSSEVPCDDSMRAMKSQLYSCY", "length": 342, "header": "tr|A0ABI0NZG9-1|A0ABI0NZG9_BOVIN Isoform 1 of Alpha tocopherol transfer protein like OS=Bos taurus OX=9913 GN=TTPAL PE=4 SV=1 CANONICAL=A0ABI0NZG9-1" }, "locus": { "chromosome": "13", "start_pos": 72904314, "end_pos": 72895974, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150437.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150437.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107077.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107077.1" } ] } }, { "isoform_ac": "A0ABI0NZL8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG9/entry#A0ABI0NZL8-1", "sequence": { "sequence": "MTSVRGSWELMSEESDSLRTSPSVASLSENELPPPSAPAGYVCSLTEDLVAKAREELQEKPEWRLRDVQALRDMVRKECPNLSTSLEDAFLLRFLRARKFDYDRALQLLINYHSCRRSWPEVFNNLRPSALKEVLASGFLTVLPHTDPRGCHVLCLRPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRNILPREYGGTAGELDITAWNAVLLASEEDFVREFCQPGPPCDSILGQALPPEGLSSEVPCDDSMRAMKSQLYSCY", "length": 352, "header": "tr|A0ABI0NZL8-1|A0ABI0NZL8_BOVIN Computationally mapped isoform of Alpha tocopherol transfer protein like OS=Bos taurus OX=9913 GN=TTPAL PE=4 SV=1 CANONICAL=A0ABI0NZG9-1" }, "locus": { "chromosome": "13", "start_pos": 72904314, "end_pos": 72895359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148263.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148263.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105981.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105981.1" } ] } }, { "isoform_ac": "F1MTT2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG9/entry#F1MTT2-1", "sequence": { "sequence": "MSEESDSLRTSPSVASLSENELPPPSAPAGYVCSLTEDLVAKAREELQEKPEWRLRDVQALRDMVRKECPNLSTSLEDAFLLRFLRARKFDYDRALQLLINYHSCRRSWPEVFNNLRPSALKEVLASGFLTVLPHTDPRGCHVLCLRPVFPSRV", "length": 154, "header": "tr|F1MTT2-1|A0ABI0NZG9_BOVIN Computationally mapped isoform of Alpha tocopherol transfer protein like OS=Bos taurus OX=9913 GN=TTPAL PE=4 SV=2 CANONICAL=A0ABI0NZG9-1" }, "locus": { "chromosome": "13", "start_pos": 72904055, "end_pos": 72895974, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025123.6", "url": "https://www.ensembl.org/id/ENSBTAT00000025123.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025123.5", "url": "https://www.ensembl.org/id/ENSBTAP00000025123.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:526582", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526582", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZGM8-1", "protein_name": "Alpha tocopherol transfer protein like", "gene_name": "Ttpal", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEESDSVRTSPSVASLSENELPPPPPEPPGYVCSLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPYLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHGCRRSWPEVFSNLRPSALKDVLNSGFLTVLPHTDPRGCHVLCIRPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGVVILADYKGVSLSKASHFGPFIARKVIGILQDGFPIRIKAVHIVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLSSLHTSLPRNILPKEYGGTAGELDTASWNAVLLASEDDFVKEFCQPESGCDGLLGQPLLPEGLISDAQCDDSMRAMKSQLYSCY", "length": 343 }, "evidence": [ { "id": "A0ABI0NZG9", "url": "https://omabrowser.org/oma/group/A0ABI0NZG9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QZD8-1", "protein_name": "Alpha-tocopherol transfer protein-like", "gene_name": "ttpal", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADQNGHIDLGPPRDTAAGLGFPGPPPPIYTCTLTPELVAKAREELQEKPEWRLRDVQALRDMILKDHPNLRTRLDDAFLLRFLRARKFDYDRALQLLLNYHASRRAWPEVFQDLKPSTVKHVLDLGFLTVLPRPDPQGRYILCLRPGKWKPNDYPFVDNIRAIYLTLEKLIQPEETQVNGVVILVDYAGVGLSQASNPGPLLAKKVVGILQDGFPIRIKAVNIINEPRIFKGIFAIIKPFLKEKMAERYVLHGSDLASLHRVIPQSVLPQEYGGVSGRLDMSAWSRTLLEAEEEFVVEFCQPDPLEGVIMPDALLFEGEQGGAHGEDSFRHLRSQLYYCY", "length": 341 }, "evidence": [ { "id": "A0ABI0NZG9", "url": "https://omabrowser.org/oma/group/A0ABI0NZG9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3I0S6-1", "protein_name": "Alpha-tocopherol transfer protein-like", "gene_name": "Ttpal", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSEESDSQRTSPSVASLSENELPLPPPERPGYMCSLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPYLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHGCRRSWPEVFSNLRPSALKDVLNSGFLTVLPHTDPRGCHVLCIRPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRNILPKEYGGTAGELDTATWNEILLASEEDFVKEFCQPVPACDSLLDQPLLSEGLISDVQCDDSMRAMKSQLSSCY", "length": 343 }, "evidence": [ { "id": "A0ABI0NZG9", "url": "https://omabrowser.org/oma/group/A0ABI0NZG9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9BTX7-1", "protein_name": "Alpha-tocopherol transfer protein-like", "gene_name": "TTPAL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEESDSLRTSPSVASLSENELPPPPEPPGYVCSLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHSCRRSWPEVFNNLKPSALKDVLASGFLTVLPHTDPRGCHVVCIRPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRSILPKEYGGTAGELDTATWNAVLLASEDDFVKEFCQPVPACDSILGQTLLPEGLTSDAQCDDSLRAVKSQLYSCY", "length": 342 }, "evidence": [ { "id": "A0ABI0NZG9", "url": "https://omabrowser.org/oma/group/A0ABI0NZG9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D3D0-1", "protein_name": "Alpha-tocopherol transfer protein-like", "gene_name": "Ttpal", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEESDSLRTSPSVASLSENELPLPPPDPPGYVCSLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPYLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHGCRRSWPEVFSNLRPSALKDVLNSGFLTVLPHTDPRGCHVLCIRPDRWIPSNYPITENIRAVYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKVIGILQDGFPIRIKAVHIVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRNILPKEYGGTAGELDTASWNAVLLASEEDFVKEFCQPMPACDNLLGQPLLPEGLISDAQCDDSMRAMKSQLYSCY", "length": 343 }, "evidence": [ { "id": "A0ABI0NZG9", "url": "https://omabrowser.org/oma/group/A0ABI0NZG9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol bisphosphate binding", "id": "GO:1902936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902936", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZG9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NZG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG9" }, { "id": "PS50191", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRAL-TRIO", "eco_id": "ECO_0000259", "start_pos": 117, "end_pos": 282, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NV36-1", "uniprot_ac": "A0ABI0NV36", "uniprot_id": "A0ABI0NV36_BOVIN", "mass": { "chemical_mass": 81924.0, "monoisotopic_mass": 81924.0 }, "refseq": {}, "gene_names": [ { "name": "TTLL3", "type": "recommended", "evidence": [ { "id": "A0ABI0NV36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36" } ] } ], "protein_names": [ { "name": "Tubulin tyrosine ligase like 3", "type": "synonym", "evidence": [ { "id": "A0ABI0NV36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TTLL3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36", "locus": { "chromosome": "22", "start_pos": 16890461, "end_pos": 16900548, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007966", "url": "https://www.ensembl.org/id/ENSBTAG00000007966" } ] } } ], "crossref": [ { "id": "ENSBTAG00000007966", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007966", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MZ48", "url": "https://www.orthodb.org/?gene=F1MZ48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N3S4", "url": "https://www.orthodb.org/?gene=G3N3S4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45870", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45870", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45870:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45870:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "67180", "url": "https://www.rhea-db.org/rhea/67180", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NV36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NV36-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P034", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P034", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P034-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P034-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZ48", "url": "https://www.uniprot.org/uniprotkb/F1MZ48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZ48-1", "url": "https://www.uniprot.org/uniprotkb/F1MZ48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3S4", "url": "https://www.uniprot.org/uniprotkb/G3N3S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3S4-1", "url": "https://www.uniprot.org/uniprotkb/G3N3S4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAHSTLTGQQCLGSLVLWRGFSKASQHMGRLRNAKIHVERAVKQKKIFMIQGRYPVIRCLLRQRGWVEKKMVHHLGTTLPQPHKDLDSSVMGDSDTAEDEDEDEEEAFRPPQLFDFDELLEFDDLHGTHALMSRMVRNEIPYFIWTTRRDILDCRFLSKDQMINHYARAGSFTTKVGLCLNLRNLPWFDEADADSFFPRCYRLGAEDDKKAFIEDFWLTAARNVLKLVVKCEWKSNSVEEEEAPRDKQPKKQEKKPVSVSPEFVDEALCACEEHLNNLAHLDIDKDVATPPCLGPEGWSLFLQRYYQVVHEGAELRYLDTQVQRCEDILQQLRAVVPQMDMEGDRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVDCNPMMMKDGKWVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNSVHLCNNSIQKHLENSCHRHPLLPPDNMWSSQKFQAHLQETGAPNAWSTVIVPGMKAAVIHALQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVVIDWRLDRNCDTGAFELIYKQPAVEVPQYVGIRLLVEGSTIKKPLAMSHRRMAVRPALPHLLAPRGSGETPYHFPSLHSKPRLPSPHVPWPQGQVLRLQHSKLVGTKALSTTDKALMTLPTAKVLISLPPNPELKLAPNALKPKKVGLKL", "length": 717, "header": "tr|A0ABI0NV36-1|A0ABI0NV36_BOVIN Isoform 1 of Tubulin tyrosine ligase like 3 OS=Bos taurus OX=9913 GN=TTLL3 PE=4 SV=1 CANONICAL=A0ABI0NV36-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NV36-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36/entry#A0ABI0NV36-1", "sequence": { "sequence": "MAAAHSTLTGQQCLGSLVLWRGFSKASQHMGRLRNAKIHVERAVKQKKIFMIQGRYPVIRCLLRQRGWVEKKMVHHLGTTLPQPHKDLDSSVMGDSDTAEDEDEDEEEAFRPPQLFDFDELLEFDDLHGTHALMSRMVRNEIPYFIWTTRRDILDCRFLSKDQMINHYARAGSFTTKVGLCLNLRNLPWFDEADADSFFPRCYRLGAEDDKKAFIEDFWLTAARNVLKLVVKCEWKSNSVEEEEAPRDKQPKKQEKKPVSVSPEFVDEALCACEEHLNNLAHLDIDKDVATPPCLGPEGWSLFLQRYYQVVHEGAELRYLDTQVQRCEDILQQLRAVVPQMDMEGDRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVDCNPMMMKDGKWVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNSVHLCNNSIQKHLENSCHRHPLLPPDNMWSSQKFQAHLQETGAPNAWSTVIVPGMKAAVIHALQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVVIDWRLDRNCDTGAFELIYKQPAVEVPQYVGIRLLVEGSTIKKPLAMSHRRMAVRPALPHLLAPRGSGETPYHFPSLHSKPRLPSPHVPWPQGQVLRLQHSKLVGTKALSTTDKALMTLPTAKVLISLPPNPELKLAPNALKPKKVGLKL", "length": 717, "header": "tr|A0ABI0NV36-1|A0ABI0NV36_BOVIN Isoform 1 of Tubulin tyrosine ligase like 3 OS=Bos taurus OX=9913 GN=TTLL3 PE=4 SV=1 CANONICAL=A0ABI0NV36-1" }, "locus": { "chromosome": "22", "start_pos": 16912346, "end_pos": 16889267, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149423.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149423.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104034.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104034.1" } ] } }, { "isoform_ac": "A0ABI0P034-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36/entry#A0ABI0P034-1", "sequence": { "sequence": "MKGGERRGAYPTPTPHLSAGSLVLWRGFSKASQHMGRLRNAKIHVERAVKQKKIFMIQGRYPVIRCLLRQRGWVEKKMVHHLGTTLPQPHKDLDSSVMGDSDTAEDEDEDEEEAFRPPQLFDFDELLEFDDLHGTHALMSRMVRNEIPYFIWTTRRDILDCRFLSKDQMINHYARAGSFTTKVGLCLNLRNLPWFDEADADSFFPRCYRLGAEDDKKAFIEDFWLTAARNVLKLVVKCEWKSNSVEEEEAPRDKQPKKQEKKPVSVSPEFVDEALCACEEHLNNLAHLDIDKDVATPPCLGPEGWSLFLQRYYQVVHEGAELRYLDTQVQRCEDILQQLRAVVPQMDMEGDRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVDCNPMMMKDGKWVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNSVHLCNNSIQKHLENSCHRHPLLPPDNMWSSQKFQAHLQETGAPNAWSTVIVPGMKAAVIHALQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVVIDWRLDRNCDTGAFELIYKQPAVEVPQYVGIRLLVEGSTIKKPLAMSHRRMAVRPALPHLLAPRGSGETEVSGSVRKLPEVAQLRRGRAGMQTQPLTTSQASTASPGCLLPMCPGPRGRSSDYSTASWWALRPCRPQTRP", "length": 713, "header": "tr|A0ABI0P034-1|A0ABI0P034_BOVIN Computationally mapped isoform of Tubulin tyrosine ligase like 3 OS=Bos taurus OX=9913 GN=TTLL3 PE=4 SV=1 CANONICAL=A0ABI0NV36-1" }, "locus": { "chromosome": "22", "start_pos": 16910402, "end_pos": 16889371, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142579.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142579.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106171.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106171.1" } ] } }, { "isoform_ac": "F1MZ48-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36/entry#F1MZ48-1", "sequence": { "sequence": "MDMEGDRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVDCNPMMMKDGKWVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNSVHLCNNSIQKHLENSCHRHPLLPPDNMWSSQKFQAHLQETGAPNAWSTVIVPGMKAAVIHALQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVVIDWRLDRTVTRGPLSSSTSSLPWRCPSMWVSGF", "length": 261, "header": "tr|F1MZ48-1|A0ABI0NV36_BOVIN Computationally mapped isoform of Tubulin tyrosine ligase like 3 OS=Bos taurus OX=9913 GN=TTLL3 PE=4 SV=1 CANONICAL=A0ABI0NV36-1" }, "locus": { "chromosome": "22", "start_pos": 16900416, "end_pos": 16890594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000030820.6", "url": "https://www.ensembl.org/id/ENSBTAT00000030820.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030790.3", "url": "https://www.ensembl.org/id/ENSBTAP00000030790.3" } ] } }, { "isoform_ac": "G3N3S4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36/entry#G3N3S4-1", "sequence": { "sequence": "MAAAHSTLTGQQCLGSLVLWRGFSKASQHMGRLRNAKIHVERAVKQKKIFMIQGRYPVIRCLLRQRGWVEKKMVHHLGTTLPQPHKDLDSSVMGDSDTAEDEDEDEEEAFRPPQLFDFDELLEFDDLHGTHALMSRMVRNEIPYFIWTTRRDILDCRFLSKDQMINHYARAGSFTTKVGLCLNLRNLPWFDEADADSFFPRCYRLGAEDDKKAFIEDFWLTAARNVLKLVVKCEWKSNSVEEEEAPRDKQPKKQEKKPVSVSPEFVDEALCACEEHLNNLAHLDIDKDVATPPCLGPEGWSLFLQRYYQVVHEGAELRYLDTQVQRCEDILQQLRAVVPQMDMEGDRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVDCNPMMMKDGKWVVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNSVHLCNNSIQKHLENSCHRHPLLPPDNMWSSQKFQAHLQETGAPNAWSTVIVPGMKAAVIHALQTSQDTVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVVIDWRLDRNCDTGAFELIYKQPLTTSQASTASPGCLLPMCPGPRGRSSDYSTASWWALRPCRPQTRP", "length": 634, "header": "tr|G3N3S4-1|A0ABI0NV36_BOVIN Computationally mapped isoform of Tubulin tyrosine ligase like 3 OS=Bos taurus OX=9913 GN=TTLL3 PE=4 SV=4 CANONICAL=A0ABI0NV36-1" }, "locus": { "chromosome": "22", "start_pos": 16912346, "end_pos": 16889371, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065735.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065735.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056585.4", "url": "https://www.ensembl.org/id/ENSBTAP00000056585.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36" } ], "pmid": "" }, { "name": "ligase activity", "id": "GO:0016874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36" } ], "pmid": "" }, { "name": "protein-glycine ligase activity, initiating", "id": "GO:0070736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070736", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV36", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV36" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 541, "end_pos": 543, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "67180", "name": "", "equation": "L-glutamyl-[protein] + glycine + ATP = glycyl-L-glutamyl-[protein] + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "67180", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/67180" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 449, "end_pos": 451 }, { "start_pos": 541, "end_pos": 543 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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}, { "id": "A0AAA9SEW4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TED6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TED6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TED6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TED6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NX25", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NX25-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MKU1", "url": "https://www.uniprot.org/uniprotkb/F1MKU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MKU1-1", "url": "https://www.uniprot.org/uniprotkb/F1MKU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1017, "header": "tr|A0ABI0NX25-1|A0ABI0NX25_BOVIN Isoform 1 of Antiviral innate immune response receptor RIG-I OS=Bos taurus OX=9913 GN=RIGI PE=3 SV=1 CANONICAL=A0ABI0NX25-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SEW4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25/entry#A0AAA9SEW4-1", "sequence": { "sequence": "MTAEQRRNLHAFRDYVRKILDPTYILSYMTPWFRDDVVQHIQAKKNNKGPMEAASLFLQVLLELQEEGWFRGFLDALQQAGYSGLYEAIESWDFQKLEKLEEYRLLLKRLQPEFKTTINPEDILPEISGCLLNQECEEIIQALKNWIEENPKLSFLKPGILTGRGRTNQTMGMTLPAQKCALDAFRTNRDSKILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSKCFLLTSNADVIEKEKLNICQEKMMNESISRLQGWNEAVFKEKIRQIQIQEKLIRDSQGKVKPVVDKKNKKLLCGKCKTFACYTADIRVVEECHFTVVRDAFRECFVTKLHPRPKKFGSFDKKAKIFCARKDCLHDWGIHMKYKTFEIPVIKIESFVVEDVATGAQTLYAKWKDFNFEKIPFDAAEMSPWAQDLNLQGVDGLE", "length": 439, "header": "tr|A0AAA9SEW4-1|A0ABI0NX25_BOVIN Computationally mapped isoform of Antiviral innate immune response receptor RIG-I OS=Bos taurus OX=9913 GN=RIGI PE=3 SV=1 CANONICAL=A0ABI0NX25-1" }, "locus": { "chromosome": "8", "start_pos": 11604092, "end_pos": 11559850, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113410.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113410.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082135.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082135.1" } ] } }, { "isoform_ac": "A0AAA9TED6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25/entry#A0AAA9TED6-1", "sequence": { "sequence": 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"length": 1017, "header": "tr|A0ABI0NX25-1|A0ABI0NX25_BOVIN Isoform 1 of Antiviral innate immune response receptor RIG-I OS=Bos taurus OX=9913 GN=RIGI PE=3 SV=1 CANONICAL=A0ABI0NX25-1" }, "locus": { "chromosome": "8", "start_pos": 11604092, "end_pos": 11559625, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146048.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146048.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105673.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105673.1" } ] } }, { "isoform_ac": "F1MKU1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25/entry#F1MKU1-1", "sequence": { "sequence": "MTAEQRRNLHAFRDYVRKILDPTYILSYMTPWFRDGYSGLYEAIESWDFQKLEKLEEYRLLLKRLQPEFKTTINPEDILPEISGCLLNQECEEIIQISSNKGLMAGAEKMVECLLRSDKENWPKTLKLALEKEESKFSELWMVEKGAENVQMKDLEDDEMKTLDVHIVYKEEPESQNLSQNSCSSEVPPTYSPLKPRNYQLELALPAQKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGRKGKVVVFAVQVPLYEQQKSVFSEYFERFGYKVSGISGETADNISVEQIVENNDIIILTPQILVNSLKDGTIPSLSIFTLMIFDECHNTNKHHPYNMIMFHYLDQKLGGSSDSLPQVIGLTASVGVGDAKNTAEATEYICKLCASLDTAVVTTVRDNLEELEEVVYKPQKFFRKVESRTTDRFKRIISQLMAETEALAKSIFEELGTVTLENLSRIQNRNFGTQKYEQWIIAVQKACMVFQMPDKEEESRICKALFLYTSHLRKYNDALIINEDARMKDALNYLKNFFKNVRAAGFDAIEQDLTQRFEEKLLELEGISMDPSNENAKLKDLCFILQEEYHLNPETRTILFVKTRALVDALKNWIEENPKLSFLKPGILTGRGRTNQTMGMTLPAQKCALDAFRTNRDSKILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSKCFLLTSNADVIEKEKLNICQEKMMNESISRLQGWNEAVFKEKIRQIQIQEKLIRDSQGKVKPVVDKKNKKLLCGKCKTFACYTADIRVVEECHFTVVRDAFRECFVTKLHPRPKKFGSFDKKAKIFCARKDCLHDWGIHMKYKTFEIPVIKIESFVVEDVATGAQTLYAKWKDFNFEKIPFDAAEMSPWAQDLNLQGVDGLE", "length": 897, "header": "tr|F1MKU1-1|A0ABI0NX25_BOVIN Computationally mapped isoform of Antiviral innate immune response receptor RIG-I OS=Bos taurus OX=9913 GN=RIGI PE=3 SV=4 CANONICAL=A0ABI0NX25-1" }, "locus": { "chromosome": "8", "start_pos": 11604092, "end_pos": 11559850, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061377.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061377.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053514.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053514.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:504760", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504760", "resource": "KEGG Pathway" }, { "id": "R-BTA-1169408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1169408", "resource": "Reactome", "description": "ISG15 antiviral mechanism" }, { "id": "R-BTA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "resource": 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Function", "total": 8, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NX25", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NX25", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NX25", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NX25", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NX25", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NX25", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NX25", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NX25", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ], "pmid": "" } ] }, { "name": 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"A0ABI0NX25", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 746, "end_pos": 748, "annotation": "n_glycosylation_sequon" }, { "start_pos": 840, "end_pos": 842, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", "F1N2W9-1", "E1BB03-1", "E1BMP7-1", "A0JND9-1", "E1BAS6-1", "A0AAA9RXM7-1", "Q59HJ6-1", "Q2KJ94-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "A0AAF6Z0E4-1", "G3MZH7-1", "F1MKC7-1", "A0AAA9S7V9-1", "A0AAF6YME1-1", "F1MFR1-1", "Q3T084-1", "E1B7X9-1", "A0ABI0P204-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "R-BTA-1169406", "name": "ISGylation of host proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5PJC4-1", "A0ABI0NX25-1", "A2VEA3-1", "E1B8P9-1", "A0ABI0P1V8-1", "A0A3Q1MAR8-1" ], "evidence": [ { "id": "R-BTA-1169406", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1169406" } ] }, { "id": "R-BTA-1678841", "name": "Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NX25-1", "E1B8P9-1", "A0ABI0P1V8-1", "A0A3Q1MAR8-1" ], "evidence": [ { "id": "R-BTA-1678841", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1678841" } ] }, { "id": "R-BTA-5690159", "name": "USP21 deubiquitinates RIPK1,DDX58", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NX25-1", "Q5E953-1" ], "evidence": [ { "id": "R-BTA-5690159", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5690159" } ] }, { "id": "R-BTA-5696564", "name": "USP25 deubiquitinates DDX58", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NX25-1", "A0AAA9S5V1-1" ], "evidence": [ { "id": "R-BTA-5696564", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5696564" } ] }, { "id": "R-BTA-5696600", "name": "USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A7MBD1-1", "A0ABI0NX25-1", "A6H7A0-1", "A0AAA9SPF3-1", "A0A3Q1MAX7-1", "A0A3Q1MC38-1", "A0A3Q1MME1-1" ], "evidence": [ { "id": "R-BTA-5696600", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5696600" } ] }, { "id": "R-BTA-8985153", "name": "OASL binds DDX58", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NX25-1" ], "evidence": [ { "id": "R-BTA-8985153", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8985153" } ] }, { "id": "R-BTA-936390", "name": "CYLD mediated deubiquitination of DDX58 (RIG-I)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-BTA-918191" ], "output_participant_list": [], "enzyme_list": [ "A0ABI0NX25-1", "Q1RMU2-1" ], "evidence": [ { "id": "R-BTA-936390", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-936390" } ] }, { "id": "R-BTA-936563", "name": "ISGylation of DDX58", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5PJC4-1", "A0ABI0NX25-1" ], "evidence": [ { "id": "R-BTA-936563", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-936563" } ] }, { "id": "R-BTA-9927247", "name": "ISGylation of DDX58 (RIG-I)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-BTA-168917" ], "output_participant_list": [], "enzyme_list": [ "A5PJC4-1", "A0ABI0NX25-1", "A2VEA3-1" ], "evidence": [ { "id": "R-BTA-9927247", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9927247" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-168917", "participant_name": "DDX58 [cytosol]", "crossref": [ { "id": "F1MKU1", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000003366", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000053514", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000061377", "database": "ENSEMBL", "url": "" }, { "id": "27979", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-918191", "participant_name": "K63polyUb-DDX58 [cytosol]", "crossref": [ { "id": "F1MKU1", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000003366", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000053514", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000061377", "database": "ENSEMBL", "url": "" }, { "id": "27979", "database": "VGNC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LG16", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] } ] }, { "uniprot_ac": "A0A3Q1LQC3", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] } ] }, { "uniprot_ac": "A0A3Q1LSH0", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] } ] }, { "uniprot_ac": "A0A3Q1LT80", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] } ] }, { "uniprot_ac": "A0A3Q1LTL4", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] } ] }, { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1LXD0", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] } ] }, { "uniprot_ac": "A0A3Q1M0A4", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A3Q1M0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0A4" } ] } ] }, { "uniprot_ac": "A0A3Q1M155", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] } ] }, { "uniprot_ac": "A0A3Q1M493", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] } ] }, { "uniprot_ac": "A0A3Q1M7R9", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1M7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R9" } ] } ] }, { "uniprot_ac": "A0A3Q1MAR8", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] } ] }, { "uniprot_ac": "A0A3Q1MAX7", "gene_name": "LOC112446467", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of 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"id": "A0AAA9RUK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUK3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0AAA9RUK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUK3" } ] } ] }, { "uniprot_ac": "A0AAA9RXI8", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z733" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAF6Z733", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z733" } ] } ] }, { "uniprot_ac": "A0ABI0NSA6", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0NSA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0NSA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA6" } ] } ] }, { "uniprot_ac": "A0ABI0NX25", "gene_name": "RIGI", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0NX25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0NX25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ] } ] }, { "uniprot_ac": "A0ABI0NXS3", "gene_name": "DDX42", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0NXS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0NXS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3" } ] } ] }, { "uniprot_ac": "A0ABI0P1V8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] } ] }, { "uniprot_ac": "A0ABI0P204", "gene_name": "LOC112446470", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ] } ] }, { "uniprot_ac": "A0ABI0P3F2", "gene_name": "DDX3Y", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] } ] }, { "uniprot_ac": "A0ABI0P467", "gene_name": "SKIC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] } ] }, { "uniprot_ac": "A0JND9", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] } ] }, { "uniprot_ac": "A1A4H6", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A1A4H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4H6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A1A4H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4H6" } ] } ] }, { "uniprot_ac": "A2VEA3", "gene_name": "ARIH1", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A2VEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VEA3" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A2VEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VEA3" } ] } ] }, { "uniprot_ac": "A4FUD9", "gene_name": "MCM3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": 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2 ADP.", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] } ] }, { "uniprot_ac": "A5PJC4", "gene_name": "UBE2L6", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] } ] }, { "uniprot_ac": "A5PJI5", "gene_name": "GET3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": 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the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] } ] }, { "uniprot_ac": "A6QQR4", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] } ] }, { "uniprot_ac": "A7MBD1", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] } ] }, { "uniprot_ac": "A7YSY2", "gene_name": "AFG2B", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] } ] }, { "uniprot_ac": "A7Z019", "gene_name": "SMARCA4", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A7Z019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7Z019" } ] } ] }, { "uniprot_ac": "E1B7X9", "gene_name": "SMARCAD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1B7X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7X9" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] 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"E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] } ] }, { "uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] } ] }, { "uniprot_ac": "Q0IIK5", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0IIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIK5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q0IIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIK5" } ] } ] }, { "uniprot_ac": "Q0V8B7", "gene_name": "MCM5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0V8B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8B7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q0V8B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8B7" } ] } ] }, { "uniprot_ac": "Q0V8H6", "gene_name": "MOV10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "5.6.2.5", "activity": "n ATP + n H2O + wound RNA = n ADP + n phosphate + unwound RNA.", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "5.6.2.5", "activity": "", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] } ] }, { "uniprot_ac": "Q0VCX2", "gene_name": "HSPA5", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0VCX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCX2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "Q0VCX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCX2" } ] } ] }, { "uniprot_ac": "Q0VD48", "gene_name": "VPS4B", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0VD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD48" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "Q0VD48", "database": "UniProtKB", "url": 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[ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q1RMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "Q1RMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT1" } ] } ] }, { "uniprot_ac": "Q1RMU2", "gene_name": "CYLD", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "Q1RMU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMU2" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "Q1RMU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMU2" } ] } ] }, { "uniprot_ac": "Q28141", "gene_name": "DHX9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q28141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28141" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q28141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28141" } ] } ] }, { "uniprot_ac": "Q29S22", "gene_name": "DDX47", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q29S22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29S22" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q29S22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29S22" } ] } ] }, { "uniprot_ac": "Q2HJF8", "gene_name": "RHOT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q2HJF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF8" } ] } ] }, { "uniprot_ac": "Q2KIZ8", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] } ] }, { "uniprot_ac": "Q2KJ94", "gene_name": "RAD51", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q2KJ94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ94" } ] } ] }, { "uniprot_ac": "Q2KJI7", "gene_name": "AFG3L2", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKZ1" } ] } ] }, { "uniprot_ac": "Q2NL08", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL08" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2NL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL08" } ] } ] }, { "uniprot_ac": "Q2NL22", "gene_name": "EIF4A3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NL22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL22" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2NL22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL22" } ] } ] }, { "uniprot_ac": "Q2T9X2", "gene_name": "CCT4", "activity": [ { "ec_number": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" }, { "id": "PRU01125", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01125" } ], "binding_site_uniprot": 947, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 947, "end_pos": 947, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.4.13", "ec_name": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "3.6.4.13", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13" }, { "id": "3.6.4.13", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.4.13" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 297, "end_pos": 299 }, { "start_pos": 404, "end_pos": 406 }, { "start_pos": 573, "end_pos": 575 }, { "start_pos": 746, "end_pos": 748 }, { "start_pos": 840, "end_pos": 842 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NZJ9-1", "uniprot_ac": "A0ABI0NZJ9", "uniprot_id": "A0ABI0NZJ9_BOVIN", "mass": { "chemical_mass": 102824.0, "monoisotopic_mass": 102824.0 }, "refseq": { "ac": "NP_001179872", "name": "tubulin polyglutamylase TTLL7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179872" }, "gene_names": [ { "name": "TTLL7", "type": "recommended", "evidence": [ { "id": "A0ABI0NZJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9" } ] }, { "name": "TTLL7", "type": "synonym", "evidence": [ { "id": "NP_001179872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179872" } ] } ], "protein_names": [ { "name": "Tubulin tyrosine ligase like 7", "type": "synonym", "evidence": [ { "id": "A0ABI0NZJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9/entry#names_and_taxonomy" } ] }, { "name": "tubulin polyglutamylase TTLL7", "type": "synonym", "evidence": [ { "id": "NP_001179872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179872" } ] }, { "name": "tubulin tyrosine ligase-like family, member 7", "type": "synonym", "evidence": [ { "id": "NP_001179872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179872" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZJ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TTLL7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9", "locus": { "chromosome": "3", "start_pos": 60258477, "end_pos": 60110989, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003322", "url": "https://www.ensembl.org/id/ENSBTAG00000003322" } ] } } ], "crossref": [ { "id": "ENSBTAG00000003322", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003322", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "522221", "url": "https://www.ncbi.nlm.nih.gov/gene/522221", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:522221", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522221", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MNCCRRI", "url": "https://omabrowser.org/oma/group/MNCCRRI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEK7", "url": "https://www.orthodb.org/?gene=E1BEK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12241:SF147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12241:SF147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179872", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179872", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0L8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0R5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0R5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0R5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGK2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5Q0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZJ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEK7", "url": "https://www.uniprot.org/uniprotkb/E1BEK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEK7-1", "url": "https://www.uniprot.org/uniprotkb/E1BEK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSLPQERVIQGPTPLDLNTELPYQSTMKRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKIAELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYAFVPRTWIFPAEYTQFQNYMKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKKGVLLNALKLLNIRTSDKRKNLAKQKAEAQRRLYGQNSIKRPLPGSSDWEQQRHQLEKRKEELKERLAQVRKQISKEEHENRHMGNYRRIYPPEDKTLLEKYENLLAVAFQTFLSGRAASFQRELNNPLKRMKEEDILDLLEQCEIDDEKLMGKTTKSRGPKPLSSMPESTEIMKRQKYYSSDSSYGSSNSSSESDENEKDEYQNKKREKQVTYNLKQSNHYKLIQPSSSIRRSVSCPRSISSQSPSCADIRPFSAQQVISASRPTSGSRSHSLNRASSYTRHLPQSNDASSSDSLMSESLRKLRPKEQEDDLTSQTLFVLKDMKIRFPGKSDAESLILIEDIIDNWKYHKTKVASYWLIKLDSVKQRKVLDIVKTSVRTVLPRIWKVPDVEEVNLYRIFNRVFNRLLWSHGQGLWNCFCDSGSSWESIFNKSPEVVTPLQLQCCQRLVELCKQCLLVVYKYASDSRGSLSGIGTDWGNSRYLLPGSTQFFMRTPTYNLKYSSPGMARSNVLFTSRYGHL", "length": 887, "header": "tr|A0ABI0NZJ9-1|A0ABI0NZJ9_BOVIN Isoform 1 of Tubulin tyrosine ligase like 7 OS=Bos taurus OX=9913 GN=TTLL7 PE=3 SV=1 CANONICAL=A0ABI0NZJ9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LZI2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9/entry#A0A3Q1LZI2-1", "sequence": { "sequence": "MPSLPQERVIQGPTPLDLNTELPYQSTMKRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKIAELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYAFVPRTWIFPAEYTQFQNYMKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKKGVLLNALKLLNIRTSDKRKNLAKQKAEAQRRLYGQNSIKRPLPGSSDWEQQRHQLEKRKEELKERLAQVRKQISKEEHENRHMGNYRRIYPPEDKTLLEKYENLLAVAFQTFLSGRAASFQRELNNPLKRMKEEDILDLLEQCEIDDEKLMGKTTKSRGPKPLSSMPESTEIMKRQKYYSSDSSYGSSNSSSESDENEKDEYQNKKREKQVTYNLKQSNHYKLIQPSSSIRRSVSCPRSISSQSPSCADIRPFSAQQVISASRPTSGSRSHSLNRASSYTRHLPQSNDASSSDSLMSESLRKLRPKEQEDDLTSQTLFVLKDMKIRFPGKSDAESLILIEDIIDNWKYHKTKVASYWLIKLDSVKQRKVFTARKYTILHENTNLQLEIQFTWNGSLQCFVYIPIWPFVKQKGRSPWVMHNSNSYFPQFNIEKTVTINYCFMYI", "length": 811, "header": "tr|A0A3Q1LZI2-1|A0ABI0NZJ9_BOVIN Computationally mapped isoform of Tubulin tyrosine ligase like 7 OS=Bos taurus OX=9913 GN=TTLL7 PE=3 SV=1 CANONICAL=A0ABI0NZJ9-1" }, "locus": { "chromosome": "3", "start_pos": 60257580, "end_pos": 60166703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086227.3", "url": "https://www.ensembl.org/id/ENSBTAT00000086227.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066265.1", "url": "https://www.ensembl.org/id/ENSBTAP00000066265.1" } ] } }, { "isoform_ac": "A0A3Q1M0L8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9/entry#A0A3Q1M0L8-1", "sequence": { "sequence": "MPSLPQERVIQGPTPLDLNTELPYQSTMKRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKIAELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYAFVPRTWIFPAEYTQFQNYMKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKKGVLLNALKLLNIRTSDKRKNLAKQKAEAQRRLYGQNSIKRPLPGSSDWEQQRHQLEKRKEELKERLAQVRKQISKEEHENRHMGNYRRIYPPEDKTLLEKYENLLAVAFQTFLSGRAASFQRELNNPLKRMKEEDILDLLEQCEIDDEKLMGKTTKSRGPKPLSSMPESTEIMKRQKYYSSDSSYGSSNSSSESDENEKDEYQNKKREKQVTYNLKQSNHYKLIQPSSSIRRSVSCPRSISSQSPSCADIRPFSAQQVISASRPTSGSRSHSLNRASSYTRHLPQSNDASSSDSLMSESLRKLRPKEQEDDLTSQTLFVLKDMKIRFPGKSDAESLILIEDIIDNWKYHKTKVASYWLIKLDSVKQRKLQVRQFWELPWWLSDKELPDNGGDLGLIPGSRRSPGEGNGNSFPYSCLGNPMNRGVWRATVQGITKESDMTERLNNKNRTVLEILPLLHPSPPTWQVGSP", "length": 836, "header": "tr|A0A3Q1M0L8-1|A0ABI0NZJ9_BOVIN Computationally mapped isoform of Tubulin tyrosine ligase like 7 OS=Bos taurus OX=9913 GN=TTLL7 PE=3 SV=3 CANONICAL=A0ABI0NZJ9-1" }, "locus": { "chromosome": "3", "start_pos": 60329527, "end_pos": 60166703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068955.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068955.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061538.3", "url": "https://www.ensembl.org/id/ENSBTAP00000061538.3" } ] } }, { "isoform_ac": "A0A3Q1M0R5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9/entry#A0A3Q1M0R5-1", "sequence": { "sequence": "MPSLPQERVIQGPTPLDLNTELPYQSTMKRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKIAELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYAFVPRTWIFPAEYTQFQNYMKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKKGVLLNALKLLNIRTSDKRKNLAKQKAEAQRRLYGQNSIKRPLPGSSDWEQQRHQLEKRKEELKERLAQVRKQISKEEHENRHMGNYRRIYPPEDKTLLEKYENLLAVAFQTFLSGRAASFQRELNNPLKRMKEEDILDLLEQCEIDDEKLMGKTTKSRGPKTQIAHYVVKFLKKL", "length": 543, "header": "tr|A0A3Q1M0R5-1|A0ABI0NZJ9_BOVIN Computationally mapped isoform of Tubulin tyrosine ligase like 7 OS=Bos taurus OX=9913 GN=TTLL7 PE=3 SV=2 CANONICAL=A0ABI0NZJ9-1" }, "locus": { "chromosome": "3", "start_pos": 60213888, "end_pos": 60166703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073165.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073165.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066826.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066826.2" } ] } }, { "isoform_ac": "A0A3Q1MGK2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9/entry#A0A3Q1MGK2-1", "sequence": { "sequence": "MPSLPQERVIQGPTPLDLNTELPYQSTMKRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKIAELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYAFVPRTWIFPAEYTQFQNYMKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKKGVLLNALKLLNIRTSDKRKNLAKQKAEAQRRLYGQNSIKRPLPGSSDWEQQRHQLEKRKEELKERLAQVRKQISKEEHENRHMGNYRRIYPPEDKTLLEKYENLLAVAFQTFLSGRAASFQRELNNPLKRMKEEDILDLLEQCEIDDEKLMGKTTKSRGPKPLSSMPESTEIMKRQKYYSSDSSYGSSNSSSESDENEKDEYQNKKREKQVTYNLKQSNHYKLIQPSSSIRRSVSCPRSISSQSPSCADIRPFSAQQVISASRPTSGSRSHSLNRASSYTRHLPQSNDASSSDSLMSESLRKLRPKEQEDDLTSQTLFVLKDMKIRFPGKSDAESLILIEDIIDNWKYHKTKVASYWLIKLDSVKQRKVLDIVKTSVRTVLPRIWKVPDVEEVNLYRIFNRVFNRLLWSHGQGLWNCFCDSGYLLPGSTQFFMRTPTYNLKYSSPGMARSNVLFTSRYGHL", "length": 829, "header": "tr|A0A3Q1MGK2-1|A0ABI0NZJ9_BOVIN Computationally mapped isoform of Tubulin tyrosine ligase like 7 OS=Bos taurus OX=9913 GN=TTLL7 PE=3 SV=2 CANONICAL=A0ABI0NZJ9-1" }, "locus": { "chromosome": "3", "start_pos": 60257473, "end_pos": 60166703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080322.3", "url": "https://www.ensembl.org/id/ENSBTAT00000080322.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073382.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073382.2" } ] } }, { "isoform_ac": "A0AAA9S5Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9/entry#A0AAA9S5Q0-1", "sequence": { "sequence": "MPSLPQERVIQGPTPLDLNTELPYQSTMKRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKIAELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYAFVPRTWIFPAEYTQFQNYMKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKKGVLLNALKLLNIRTSDKRKNLAKQKAEAQRRLYGQNSIKRPLPGSSDWEQQRHQLEKRKEELKERLAQVRKQISKEEHENRHMGNYRRIYPPEDKTLLEKYENLLAVAFQTFLSGRAASFQRELNNPLKRMKEEDILDLLEQCEIDDEKLMGKTTKSRGPKPLSSMPESTEIMKRQKYYSSDSSYGSSNSSSESDENEKDEYQNKKREKQVTYNLKQSNHYKLIQPSSSIRRSVSCPRSISSQSPSCADIRPFSAQQVISASRPTSGSRSHSLNRASSYTRHLPQSNDASSSDSLMSESLRKLRPKEQEDDLTSQTLFVLKDMKIRFPGKSDAESLILIEDIIDNWKYHKTKVASYWLIKLDSVKQRKVLDIVKTSVRTVLPRIWKVPDVEEVNLYRIFNRVFNRLLWSHGQGLWNCFCDSGSSWESIFNKSPEVVTPLQLQCCQRLVELCKQCLLVVYKYASDSRGSLSGIGTDWGNSSHPVVFDSS", "length": 856, "header": "tr|A0AAA9S5Q0-1|A0ABI0NZJ9_BOVIN Computationally mapped isoform of Tubulin tyrosine ligase like 7 OS=Bos taurus OX=9913 GN=TTLL7 PE=3 SV=1 CANONICAL=A0ABI0NZJ9-1" }, "locus": { "chromosome": "3", "start_pos": 60253253, "end_pos": 60166703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121467.2", "url": "https://www.ensembl.org/id/ENSBTAT00000121467.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079169.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079169.1" } ] } }, { "isoform_ac": "A0ABI0NZJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9/entry#A0ABI0NZJ9-1", "sequence": { "sequence": "MPSLPQERVIQGPTPLDLNTELPYQSTMKRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKIAELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYAFVPRTWIFPAEYTQFQNYMKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKKGVLLNALKLLNIRTSDKRKNLAKQKAEAQRRLYGQNSIKRPLPGSSDWEQQRHQLEKRKEELKERLAQVRKQISKEEHENRHMGNYRRIYPPEDKTLLEKYENLLAVAFQTFLSGRAASFQRELNNPLKRMKEEDILDLLEQCEIDDEKLMGKTTKSRGPKPLSSMPESTEIMKRQKYYSSDSSYGSSNSSSESDENEKDEYQNKKREKQVTYNLKQSNHYKLIQPSSSIRRSVSCPRSISSQSPSCADIRPFSAQQVISASRPTSGSRSHSLNRASSYTRHLPQSNDASSSDSLMSESLRKLRPKEQEDDLTSQTLFVLKDMKIRFPGKSDAESLILIEDIIDNWKYHKTKVASYWLIKLDSVKQRKVLDIVKTSVRTVLPRIWKVPDVEEVNLYRIFNRVFNRLLWSHGQGLWNCFCDSGSSWESIFNKSPEVVTPLQLQCCQRLVELCKQCLLVVYKYASDSRGSLSGIGTDWGNSRYLLPGSTQFFMRTPTYNLKYSSPGMARSNVLFTSRYGHL", "length": 887, "header": "tr|A0ABI0NZJ9-1|A0ABI0NZJ9_BOVIN Isoform 1 of Tubulin tyrosine ligase like 7 OS=Bos taurus OX=9913 GN=TTLL7 PE=3 SV=1 CANONICAL=A0ABI0NZJ9-1" }, "locus": { "chromosome": "3", "start_pos": 60257473, "end_pos": 60166703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137221.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137221.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105956.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105956.1" } ] } }, { "isoform_ac": "E1BEK7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9/entry#E1BEK7-1", "sequence": { "sequence": "MPSLPQERVIQGPTPLDLNTELPYQSTMKRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKIAELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYAFVPRTWIFPAEYTQFQNYMKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKKGVLLNALKLLNIRTSDKRKNLAKQKAEAQRRLYGQNSIKRPLPGSSDWEQQRHQLEKRKEELKERLAQVRKQISKEEHENRHMGNYRRIYPPEDKTLLEKYENLLAVAFQTFLSGRAASFQRELNNPLKRMKEEDILDLLEQCEIDDEKLMGKTTKSRGPKPLSSMPESTEIMKRQKYYSSDSSYGSSNSSSESDENEKDEYQNKKREKQVTYNLKQSNHYKLIQPSSSIRRSVSCPRSISSQSPSCADIRPFSAQQVISASRPTSGSRSHSLNRASSYTRHLPQSNDASSSDSLMSESLRKLRPKEQEDDLTSQTLFVLKDMKIRFPGKSDAESLILIEDIIDNWKYHKTKVASYWLIKLDSVKQRKVLDIVKTSVRTVLPRIWKVPDVEEVNLYRIFNRVFNRLLWSHGQGLWNCFCDSGSSWESIFNKSPEVVTPLQLQCCQRLVELCKQCLLVVYKYASDSRGSLSGIGTDWGNSRLTEFQ", "length": 853, "header": "tr|E1BEK7-1|A0ABI0NZJ9_BOVIN Computationally mapped isoform of Tubulin tyrosine ligase like 7 OS=Bos taurus OX=9913 GN=TTLL7 PE=3 SV=3 CANONICAL=A0ABI0NZJ9-1" }, "locus": { "chromosome": "3", "start_pos": 60243808, "end_pos": 60166703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004304.7", "url": "https://www.ensembl.org/id/ENSBTAT00000004304.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004304.6", "url": "https://www.ensembl.org/id/ENSBTAP00000004304.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:522221", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522221", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZHC1-1", "protein_name": "Tubulin tyrosine ligase like 7", "gene_name": "TTLL7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLPNEGDNHGTTAVTLRSELPYQSTIKRKVRKKKNGVITANVAGTKYEIVRIVIQELGFVKTRDEDETANLIWSDSAVQQEKIAELRNYQRINHFPGMGEICRKDFLARNMTKMIKCQPQEYTFIPRTWIFPAEYTQFQNYVKELKKKRRQKTFIVKPANGAMGHGISLIRNGEKLQAQDHLIVQEYLDKPFLMEGYKFDLRVYILVTSCDPLKVFLYHDGLVRMGTEKYHPPSDSNLSQLYMHLTNYSVNKHNEHFERDETEDKGSKRSIKWFTEFLETNNLDVSKFWNDISELVVKTLIVAEPHVLHAYRMCRPGQAPGSDSVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKKGVLLNALKLLNIRTSDKRRNLAQQKAEAQKRLYGQGSMKRLLPGSSDWEKQRHSLERRKEELKERLAQVRKQISKEEHENRHMGNYRRIYPPDDKSLLEKYESLLATAFQTFLAGRAASLQREMNNPLKRMKEEDILDLLEQCEIDDEKLMGKCTRQRGPKPLCSMPEIAQPVRKFKNYSSDSSCDSGSSMSGSGDETEKEDHSEKKEKKVSYDLEENKYKPSERSGRMNWKPSIKNTKSPSNSSSSSSTGPIRRSVSCPRSISILSMQSHAAEHRPFSAKASLQTQRASSVNRSRSLNCSPSSSRVCQTSSLGTVNSSGSESLLQQKTKEQEVALTKETLLIFNGMRMKFPGKTDEESELIIEEIMDNWKYHKTKVASYWLVKLDSVKQRKVLDIVRTSVRAVLQHVWKAPDIENLHLYRLFNRVFNRLLWSHGQGLWNCFCNSGNSWETIFSRSTEVVTPEQLQCCQRIVQLCKHCLLVVYKYSSDSRGSLTGISPSWDDTRSLKVTDSRFAFLEVFIARTITVHHEIILVQPQLQFIWNASP", "length": 912 }, "evidence": [ { "id": "A0ABI0NZJ9", "url": "https://omabrowser.org/oma/group/A0ABI0NZJ9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7F6H8-1", "protein_name": "Tubulin polyglutamylase TTLL7 isoform X1", "gene_name": "Ttll7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLPQEGVIQGSSPLDLKTELPYQCTMKRKVRKKKKKGVITANVAGTKFEIVRLVIDELGFMKSPDEDETSNLIWCDAAVQQEKITDLQNYQRINHFPGMGEICRKDFLARNMTKMIKCRPLDYTFVPRTWIFPSEYSQFQNYVKELKKKRKQKTFIIKPANGAMGHGISLIRNGDKIPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNDSNLTQLYMHLTNYSVNKHNERFERNETEDKGSKRSIKWFTEFLHANQHDVSKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRKNLAKQKAEAQKRLYGQNSIRRLSPGSSDWEQQRHQLERRKEELKERLVQVRKQVSKEEHENRHMGNYRRIYPPEDKALLEKYDSLLSVAFQTFLSGRAASFQRELNNPLKKMKEEDLLDLLEQCEIDDEKLMGKPTRTRGPKPLCCMPESVEVMKKQKCYSSSESSFDSSCSSNSELEENEKELCQKRREQAPYNLKHTSHCKLIQQSNSMRRSVSCPRSISAHLPSSGDARPFSSQQMMPLARPTSASRSHSLNRASSYTRHLPNSNDASAANSMVNESLRQLKTKEQEDDLTSQTLFVLKDMRIRFPGKSDADSELLIDDIMDNWKHYKTKVASYWLIKLDSVKQRKVLDIVKSSIRTVLPRIWRVPDAEELSLYRIFNRVFNRLLWSHGQGLWSCFCDSGSSWESIFSKSPDVVTPLQLQCCQRVVELCKQCLLVVYKYTTETRGPISGIGPDLGNSRYLLPGSAQLLMRSSLYNMKYNSPGMTRSNVLFTSRYSHL", "length": 887 }, "evidence": [ { "id": "A0ABI0NZJ9", "url": "https://omabrowser.org/oma/group/A0ABI0NZJ9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A4Q9F0-1", "protein_name": "Tubulin polyglutamylase TTLL7", "gene_name": "Ttll7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSLPQDGVIQGSSPVDLGTELPYQCTMKRKVRKKKKKGIITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDAAVQQEKITDLQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPMDYTFVPRTWIFPSEYTQFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKVPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNERFERNETEDKGSKRSIKWFTEFLQANQHDVTKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRKNLAKQKAEAQRRLYGQNPVRRLSPGSSDWEQQRHQLERRKEELKERLLQVRKQVSQEEHENRHMGNYRRIYPPEDKALLEKYEGLLAVAFQTFLSGRAASFQREMNNPLKKMREEDLLDLLEQCEIDDEKLMGKTGRVRGPKPLCCMPECAEVTKKQKYYGSSDSSYDSSSSSSNSELDENEKELCQKRLDQVPYSLKHTSHCKIIQQPSGSHNLIYSESPVYLTTLVFLSEFPDSMRRSVSCPRSISAHLPSRGDVRPFSSQQVIPLARPTSASRSHSLNRASSYARHLPHGSDTGSTNTLNESLRQLKTKEQEDDLTSQTLFVLKDMRIRFPGKSDAESELLIEDIMDNWKHYKTKVASYWLIKLDSVKQRKVLDIVKSSIRTVLPRIWRVPDAEELSLYRIFNRVFNRLLWSHGQGLWSCFCDSGSSWESIFSKSPEVVTPLQLQCCQRLVELCKQCLLVVYKYTTETRGPISGIGPDWGNSRYLLPGSTQFLMRSPLYNMKYNSPGMTRSNVLFTSRYGRL", "length": 912 }, "evidence": [ { "id": "A0ABI0NZJ9", "url": "https://omabrowser.org/oma/group/A0ABI0NZJ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0RBT9-1", "protein_name": "Tubulin tyrosine ligase like 7", "gene_name": "Ttll7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSLPQDGVIQGSSPLELNTELPYHCTMKRKVRKKKKKGIITANVAGTKFEIVRLVIDEMGFIKTPDEDETSNLIWCDAAVQQEKITDLQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPMDYTFVPRTWIFPSEYTQFQNYVKELKKKRKQKTFIIKPANGAMGHGISLIRNGDKIPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNERFERNETEDKGSKRSIKWFTEFLQANQHDVTKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRKNLAKQKAEAQRRLYGQNPIRRLSPGSSDWEQQRHQLERRKEELKERLLQVRKQISQEEHENRHMGNYRRIYPPEDKTLLEKYEGLLAVAFQTFLSGRATSFHREMNNPLKKMREEDLLDLLEQCEIDDEKLMGKTTRVRGPKPLYCMPECAEVMKMQKYYGSSDSSYDSSGSSSNSDLDESDKELCQKRLDQVPYSFKHSKLFQQSNSMRRSVSCPRSISAHLPSRGDVRPFSSQQVIPLARPTSASRSHSLNRASSYMRHLPHSHDASSASNALVNESLRQLKTKEQEDDLTSQTLFVLKDMRIRFPGKSDAESELLIEDIMDNWKHYKTKVASYWLIKLDSVKQRKVLDIVKSSIRTVLPRIWRVPDAEELSLYRIFNRVFNRLLWSHGQGLWSSFCDSGSSWESIFNKGPEVVTPLQLQCCQRLVELCKQCLLVVYKYTTETRGPISGIGPDWGNSSPQTTNLGSPEGVQGSLSYYREMLEGICYQEVLNSS", "length": 882 }, "evidence": [ { "id": "A0ABI0NZJ9", "url": "https://omabrowser.org/oma/group/A0ABI0NZJ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZT98-1", "protein_name": "Tubulin polyglutamylase TTLL7", "gene_name": "TTLL7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSLPQEGVIQGPSPLDLNTELPYQSTMKRKVRKKKKKGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKISELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYTFVPRTWIFPAEYTQFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKWFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRRNLAKQKAEAQRRLYGQNSIKRLLPGSSDWEQQRHQLERRKEELKERLAQVRKQISREEHENRHMGNYRRIYPPEDKALLEKYENLLAVAFQTFLSGRAASFQRELNNPLKRMKEEDILDLLEQCEIDDEKLMGKTTKTRGPKPLCSMPESTEIMKRPKYCSSDSSYDSSSSSSESDENEKEEYQNKKREKQVTYNLKPSNHYKLIQQPSSIRRSVSCPRSISAQSPSSGDTRPFSAQQMISVSRPTSASRSHSLNRASSYMRHLPHSNDACSTNSQVSESLRQLKTKEQEDDLTSQTLFVLKDMKIRFPGKSDAESELLIEDIIDNWKYHKTKVASYWLIKLDSVKQRKVLDIVKTSIRTVLPRIWKVPDVEEVNLYRIFNRVFNRLLWSRGQGLWNCFCDSGSSWESIFNKSPEVVTPLQLQCCQRLVELCKQCLLVVYKYATDKRGSLSGIGPDWGNSRYLLPGSTQFFLRTPTYNLKYNSPGMTRSNVLFTSRYGHL", "length": 887 }, "evidence": [ { "id": "A0ABI0NZJ9", "url": "https://omabrowser.org/oma/group/A0ABI0NZJ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZJ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9" } ], "pmid": "" }, { "name": "ligase activity", "id": "GO:0016874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZJ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9" } ], "pmid": "" }, { "name": "tubulin-glutamic acid ligase activity", "id": "GO:0070740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070740", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZJ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZJ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZJ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZJ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZJ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 557, "end_pos": 559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 798, "end_pos": 800, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 237, "end_pos": 239 }, { "start_pos": 240, "end_pos": 242 }, { "start_pos": 250, "end_pos": 252 }, { "start_pos": 557, "end_pos": 559 }, { "start_pos": 798, "end_pos": 800 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NVB2-1", "uniprot_ac": "A0ABI0NVB2", "uniprot_id": "A0ABI0NVB2_BOVIN", "mass": { "chemical_mass": 97780.0, "monoisotopic_mass": 97780.0 }, "refseq": {}, "gene_names": [ { "name": "IWS1", "type": "recommended", "evidence": [ { "id": "A0ABI0NVB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2" } ] } ], "protein_names": [ { "name": "Protein IWS1 homolog", "type": "recommended", "evidence": [ { "id": "A0ABI0NVB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2/entry#names_and_taxonomy" } ] }, { "name": "IWS1-like protein", "type": "synonym", "evidence": [ { "id": "A0ABI0NVB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.", "evidence": [ { "database": "UniProtKB", "id": "E1BFW2", "url": "https://www.uniprot.org/uniprotkb/E1BFW2#function" }, { "database": "UniProtKB", "id": "ARBA00055001", "url": "https://www.uniprot.org/uniprotkb/ARBA00055001#function" }, { "database": "UniProtKB", "id": "A0A3Q1M8R3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8R3#function" }, { "database": "UniProtKB", "id": "A0AAA9S6V2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6V2#function" }, { "database": "UniProtKB", "id": "A0AAA9SBV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBV1#function" }, { "database": "UniProtKB", "id": "A0AAA9SS17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS17#function" }, { "database": "UniProtKB", "id": "A0ABI0NVB2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2#function" }, { "database": "UniProtKB", "id": "A0AAA9TLK4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLK4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IWS1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2", "locus": { "chromosome": "2", "start_pos": 5058185, "end_pos": 4996677, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021172", "url": "https://www.ensembl.org/id/ENSBTAG00000021172" } ] } } ], "crossref": [ { "id": "ENSBTAG00000021172", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021172", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538614", "url": "https://www.ncbi.nlm.nih.gov/gene/538614", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051037", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051037", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538614", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538614", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M8R3", "url": "https://www.orthodb.org/?gene=A0A3Q1M8R3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BFW2", "url": "https://www.orthodb.org/?gene=E1BFW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46010", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46010", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46010:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46010:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-75955", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75955", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M8R3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M8R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8R3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6V2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6V2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6V2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBV1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SS17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SS17-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SS17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLK4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLK4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVB2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVB2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFW2", "url": "https://www.uniprot.org/uniprotkb/E1BFW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFW2-1", "url": "https://www.uniprot.org/uniprotkb/E1BFW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSEYYSGDQSDDGGATPVQDERDSGSDVEDDVNEQHSGSDTGSVERHSENEPSDREDSLNKRHQVTDSDNDDPSNLNASDSESEELQRQKDSDSESEEHAEPPASDSENEDVNHHGSDSESEETRKLPASDSENEELLNGHASDSENEDVRKPPASDSEVEELPKSPASDSETEGAPKPQASDSESEEPPRNQASDSENEELPKPRISDSESEELPKPRISDSESEEPQRTQASDSENEELPKPRISDSESEDPPRQQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEEPQKGPASDSETEDASRHKQKPESEEDSDGENKGEDTEVQNDSLPADAHVDRKRFNSSDSEEEEPKRAKIDSDEDEEKEGEEEKVAKRKAAVLSDSDDEEKAWIELRPLAMKVQRLNHWTPGNSLIAAAKKSRVVSDADDSDSDVISDKSGKREKTIASDSDEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKSETQVKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMSGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPTVVMHLKKQDLKETFIDSGVMSAIKEWLSPLPDRSLPALKIREELLRILQELPSVSQETLKHSGIGRAVMYLYKHPKESRSNKDMAGKLINEWSRPIFGLTSNYKGMTREEREQRDLEQMPQRRRMNSTGGQTPRRDLEKVLTGEEKALRPGDPGFCARARVPMPSNKDYVVRPKWNVEMESSRFQGTSKKGISRLDKQMRKFTDIRKKSRSAHAVKISIEGNKMPL", "length": 871, "header": "tr|A0ABI0NVB2-1|A0ABI0NVB2_BOVIN Isoform 1 of Protein IWS1 homolog OS=Bos taurus OX=9913 GN=IWS1 PE=3 SV=1 CANONICAL=A0ABI0NVB2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M8R3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2/entry#A0A3Q1M8R3-1", "sequence": { "sequence": "DQPWNEDDGGATPVQDERDSGSDVEDDVNEQHSGSDTGSVERHSENEPSDREDSLNKRHQVTDSDNDDPSNLNASDSESEELQRQKDSDSESEEHAEPPASDSENEDVNHHGSDSESEETRKLPASDSENEELLNGHASDSENEDVRKPPASDSEVEELPKSPASDSETEGAPKPQASDSESEEPPRNQASDSENEELPKPRISDSESEELPKPRISDSESEEPQRTQASDSENEELPKPRISDSESEDPPRQQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEEPQKGPASDSETEDASRHKQKPESEEDSDGENKGEDTEVQNDSLPADAHVDRKRFNSSDSEEEEPKRAKIDSDEDEEKEGEEEKVAKRKAAVLSDSDDEEKASAKKSRVVSDADDSDSDVISDKSGKREKTIASDSDEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKSETQVKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMSGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPTVVMHLKKQDLKETFIDSGVMSAIKEWLSPLPDRSLPALKIREELLRILQELPSVSQETLKHSGIGRAVMYLYKHPKESRSNKDMAGKLINEWSRPIFGLTSNYKGMTREEREQRDLEQMPQRRRMNSTGGQTPRRDLEKVLTGEEKALRPGDPGFCARARVPMPSNKDYVVRPKWNVEMESSRFQGTSKKGISRLDKQMRKFTDIRKKSRSAHAVKISIEGNKMPL", "length": 841, "header": "tr|A0A3Q1M8R3-1|A0ABI0NVB2_BOVIN Computationally mapped isoform of Protein IWS1 homolog OS=Bos taurus OX=9913 GN=IWS1 PE=3 SV=2 CANONICAL=A0ABI0NVB2-1" }, "locus": { "chromosome": "2", "start_pos": 5057951, "end_pos": 4996836, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084838.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084838.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066506.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066506.2" } ] } }, { "isoform_ac": "A0AAA9S6V2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2/entry#A0AAA9S6V2-1", "sequence": { "sequence": "RGRRGAQTLPAESRLPWTRSITAATSQNEPSDREDSLNKRHQVTDSDNDDPSNLNASDSESEELQRQKDSDSESEEHAEPPASDSENEDVNHHGSDSESEETRKLPASDSENEELLNGHASDSENEDVRKPPASDSEVEELPKSPASDSETEGAPKPQASDSESEEPPRNQASDSENEELPKPRISDSESEELPKPRISDSESEEPQRTQASDSENEELPKPRISDSESEDPPRQQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEEPQKGPASDSETEDASRHKQKPESEEDSDGENKGEDTEVQNDSLPADAHVDRKRFNSSDSEEEEPKRAKIDSDEDEEKEGEEEKVAKRKAAVLSDSDDEEKASAAKKSRVVSDADDSDSDVISDKSGKREKTIASDSDEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKSETQVKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMSGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPTVVMHLKKQDLKETFIDSGVMSAIKEWLSPLPDRSLPALKIREELLRILQELPSVSQETLKHSGIGRAVMYLYKHPKESRSNKDMAGKLINEWSRPIFGLTSNYKGMTREEREQRDLEQMPQRRRMNSTGGQTPRRDLEKVLTGEEKALRPGDPGFCARARVPMPSNKDYVVRPKWNVEMESSRFQGTSKKGISRLDKQMRKFTDIRKKSRSAHAVKISIEGNKMPL", "length": 824, "header": "tr|A0AAA9S6V2-1|A0ABI0NVB2_BOVIN Computationally mapped isoform of Protein IWS1 homolog OS=Bos taurus OX=9913 GN=IWS1 PE=3 SV=1 CANONICAL=A0ABI0NVB2-1" }, "locus": { "chromosome": "2", "start_pos": 5057951, "end_pos": 5012518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089343.2", "url": "https://www.ensembl.org/id/ENSBTAT00000089343.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077894.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077894.1" } ] } }, { "isoform_ac": "A0AAA9SBV1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2/entry#A0AAA9SBV1-1", "sequence": { "sequence": "MDSEYYSGDQSDDGGATPVQDERDSGSDVEDDVNEQHSGSDTGSVERHSENEPSDREDSLNKRHQVTDSDNDDPSNLNASDSESEELQRQKDSDSESEEHAEPPASDSENEDVNHHGSDSESEETRKLPASDSENEELLNGHASDSENEDVRKPPASDSEVEELPKSPASDSETEGAPKPQASDSESEEPPRNQASDSENEELPKPRISDSESEELPKPRISDSESEEPQRTQASDSENEELPKPRISDSESEDPPRQQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEEPQKGPASDSETEDASRHKQKPESEEDSDGENKGEDTEVQNDSLPADAHVDRKRFNSSDSEEEEPKRAKIDSDEDEEKEGEEEKVAKRKAAVLSDSDDEEKASAAKKSRVVSDADDSDSDVISDKSGKREKTIASDSDEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKSETQVKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMSGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPTVVMHLKKQDLKETFIDSGVMSAIKEWLSPLPDRSLPALKIREELLRILQELPSVSQETLKHSGIGRAVMYLYKHPKESRSNKDMAGKLINEWSRPIFGLTSNYKGMTREEREQRDLEQMPQRRRMNSTGGQTPRRDLEKVLTGEEKALRPGDPGFCARARVPMPSNKDYVVRPKWNVEMESSRPGILKKGLSRLEKHKRRFAEQKRLSKVHRAVKFSIEGNRMPL", "length": 846, "header": "tr|A0AAA9SBV1-1|A0ABI0NVB2_BOVIN Computationally mapped isoform of Protein IWS1 homolog OS=Bos taurus OX=9913 GN=IWS1 PE=3 SV=2 CANONICAL=A0ABI0NVB2-1" }, "locus": { "chromosome": "2", "start_pos": 5053674, "end_pos": 5012565, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123894.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123894.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083565.2", "url": "https://www.ensembl.org/id/ENSBTAP00000083565.2" } ] } }, { "isoform_ac": "A0AAA9SS17-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2/entry#A0AAA9SS17-1", "sequence": { "sequence": "MWNKTDDGGATPVQDERDSGSDVEDDVNEQHSGSDTGSVERHSENEPSDREDSLNKRHQVTDSDNDDPSNLNASDSESEELQRQKDSDSESEEHAEPPASDSENEDVNHHGSDSESEETRKLPASDSENEELLNGHASDSENEDVRKPPASDSEVEELPKSPASDSETEGAPKPQASDSESEEPPRNQASDSENEELPKPRISDSESEELPKPRISDSESEEPQRTQASDSENEELPKPRISDSESEDPPRQQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEEPQKGPASDSETEDASRHKQKPESEEDSDGENKGEDTEVQNDSLPADAHVDRKRFNSSDSEEEEPKRAKIDSDEDEEKEGEEEKVAKRKAAVLSDSDDEEKASAKKSRVVSDADDSDSDVISDKSGKREKTIASDSDEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKSETQVKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMSGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPTVVMHLKKQDLKETFIDSGVMSAIKEWLSPLPDRSLPALKIREELLRILQELPSVSQETLKHSGIGRAVMYLYKHPKESRSNKDMAGKLINEWSRPIFGLTSNYKGMTREEREQRDLEQMPQRRRMNSTGGQTPRRDLEKVLTGEEKALRPGDPGFCARARVPMPSNKDYVVRPKWNVEMESSRFQGTSKKGISRLDKQMRKFTDIRKKSRSAHAVKISIEGNKMPL", "length": 840, "header": "tr|A0AAA9SS17-1|A0ABI0NVB2_BOVIN Computationally mapped isoform of Protein IWS1 homolog OS=Bos taurus OX=9913 GN=IWS1 PE=3 SV=1 CANONICAL=A0ABI0NVB2-1" }, "locus": { "chromosome": "2", "start_pos": 5057951, "end_pos": 5002298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090056.2", "url": "https://www.ensembl.org/id/ENSBTAT00000090056.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088136.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088136.1" } ] } }, { "isoform_ac": "A0AAA9TLK4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2/entry#A0AAA9TLK4-1", "sequence": { "sequence": "MDSEYYSGDQSDDGGATPVQDERDSGSDVEDDVNEQHSGSDTGSVERHSENEPSDREDSLNKRHQVTDSDNDDPSNLNASDSESEELQRQKDSDSESEEHAEPPASDSENEDVNHHGSDSESEETRKLPASDSENEELLNGHASDSENEDVRKPPASDSEVEELPKSPASDSETEGAPKPQASDSESEEPPRNQASDSENEELPKPRISDSESEELPKPRISDSESEEPQRTQASDSENEELPKPRISDSESEDPPRQQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEEPQKGPASDSETEDASRHKQKPESEEDSDGENKGEDTEVQNDSLPADAHVDRKRFNSSDSEEEEPKRAKIDSDEDEEKEGEEEKVAKRKAAVLSDSDDEEKASAAKKSRVVSDADDSDSDVISDKSGKREKTIASDSDEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKSETQVKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMSGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPTVVMHLKKQDLKETFIDSGVMSAIKEWLSPLPDRSLPALKIREELLRILQELPSVSQETLKHSGIGRAVMYLYKHPKESRSNKDMAGKLINEWSRPIFGLTSNYKGMTREEREQRDLEQMPQRRRMNSTGGQTPRRDLEKVLTGEEKALRPGDPGFCARARVPMPSNKDYVVRPKWNVEMESSRFQGTSKKGISRLDKQMRKFTDIRKKSRSAHAVKISIEGNKMPL", "length": 847, "header": "tr|A0AAA9TLK4-1|A0ABI0NVB2_BOVIN Computationally mapped isoform of Protein IWS1 homolog OS=Bos taurus OX=9913 GN=IWS1 PE=3 SV=2 CANONICAL=A0ABI0NVB2-1" }, "locus": { "chromosome": "2", "start_pos": 5057951, "end_pos": 5012565, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115813.2", "url": "https://www.ensembl.org/id/ENSBTAT00000115813.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098095.2", "url": "https://www.ensembl.org/id/ENSBTAP00000098095.2" } ] } }, { "isoform_ac": "A0ABI0NVB2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2/entry#A0ABI0NVB2-1", "sequence": { "sequence": "MDSEYYSGDQSDDGGATPVQDERDSGSDVEDDVNEQHSGSDTGSVERHSENEPSDREDSLNKRHQVTDSDNDDPSNLNASDSESEELQRQKDSDSESEEHAEPPASDSENEDVNHHGSDSESEETRKLPASDSENEELLNGHASDSENEDVRKPPASDSEVEELPKSPASDSETEGAPKPQASDSESEEPPRNQASDSENEELPKPRISDSESEELPKPRISDSESEEPQRTQASDSENEELPKPRISDSESEDPPRQQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEEPQKGPASDSETEDASRHKQKPESEEDSDGENKGEDTEVQNDSLPADAHVDRKRFNSSDSEEEEPKRAKIDSDEDEEKEGEEEKVAKRKAAVLSDSDDEEKAWIELRPLAMKVQRLNHWTPGNSLIAAAKKSRVVSDADDSDSDVISDKSGKREKTIASDSDEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKSETQVKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMSGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPTVVMHLKKQDLKETFIDSGVMSAIKEWLSPLPDRSLPALKIREELLRILQELPSVSQETLKHSGIGRAVMYLYKHPKESRSNKDMAGKLINEWSRPIFGLTSNYKGMTREEREQRDLEQMPQRRRMNSTGGQTPRRDLEKVLTGEEKALRPGDPGFCARARVPMPSNKDYVVRPKWNVEMESSRFQGTSKKGISRLDKQMRKFTDIRKKSRSAHAVKISIEGNKMPL", "length": 871, "header": "tr|A0ABI0NVB2-1|A0ABI0NVB2_BOVIN Isoform 1 of Protein IWS1 homolog OS=Bos taurus OX=9913 GN=IWS1 PE=3 SV=1 CANONICAL=A0ABI0NVB2-1" }, "locus": { "chromosome": "2", "start_pos": 5057951, "end_pos": 5012565, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148077.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148077.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105335.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105335.1" } ] } }, { "isoform_ac": "E1BFW2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2/entry#E1BFW2-1", "sequence": { "sequence": "MIRINHGMRNEPSDREDSLNKRHQVTDSDNDDPSNLNASDSESEELQRQKDSDSESEEHAEPPASDSENEDVNHHGSDSESEETRKLPASDSENEELLNGHASDSENEDVRKPPASDSEVEELPKSPASDSETEGAPKPQASDSESEEPPRNQASDSENEELPKPRISDSESEELPKPRISDSESEEPQRTQASDSENEELPKPRISDSESEDPPRQQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEEPQKGPASDSETEDASRHKQKPESEEDSDGENKGEDTEVQNDSLPADAHVDRKRFNSSDSEEEEPKRAKIDSDEDEEKEGEEEKVAKRKAAVLSDSDDEEKASAKKSRVVSDADDSDSDVISDKSGKREKTIASDSDEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKSETQVKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMSGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPTVVMHLKKQDLKETFIDSGVMSAIKEWLSPLPDRSLPALKIREELLRILQELPSVSQETLKHSGIGRAVMYLYKHPKESRSNKDMAGKLINEWSRPIFGLTSNYKGMTREEREQRDLEQMPQRRRMNSTGGQTPRRDLEKVLTGEEKALRPGDPGFCARARVPMPSNKDYVVRPKWNVEMESSRFQGTSKKGISRLDKQMRKFTDIRKKSRSAHAVKISIEGNKMPL", "length": 805, "header": "tr|E1BFW2-1|A0ABI0NVB2_BOVIN Computationally mapped isoform of Protein IWS1 homolog OS=Bos taurus OX=9913 GN=IWS1 PE=3 SV=4 CANONICAL=A0ABI0NVB2-1" }, "locus": { "chromosome": "2", "start_pos": 5057951, "end_pos": 4996828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028213.8", "url": "https://www.ensembl.org/id/ENSBTAT00000028213.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028213.7", "url": "https://www.ensembl.org/id/ENSBTAP00000028213.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538614", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538614", "resource": "KEGG Pathway" }, { "id": "R-BTA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-BTA-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2" } ], "pmid": "" }, { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 771, "end_pos": 773, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NVB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB2" }, { "id": "PS51319", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51319" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TFIIS N-terminal", "eco_id": "ECO_0000259", "start_pos": 666, "end_pos": 744, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 372, "end_pos": 374 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 771, "end_pos": 773 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NW99-1", "uniprot_ac": "A0ABI0NW99", "uniprot_id": "A0ABI0NW99_BOVIN", "mass": { "chemical_mass": 47013.0, "monoisotopic_mass": 47013.0 }, "refseq": { "ac": "XP_010806853", "name": "A-kinase anchoring protein 7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806853" }, "gene_names": [ { "name": "AKAP7", "type": "recommended", "evidence": [ { "id": "A0ABI0NW99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99" } ] }, { "name": "AKAP7", "type": "synonym", "evidence": [ { "id": "XP_010806853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806853" } ] } ], "protein_names": [ { "name": "A-kinase anchoring protein 7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010806853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806853" } ] }, { "name": "A-kinase anchoring protein 7", "type": "synonym", "evidence": [ { "id": "A0ABI0NW99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW99", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AKAP7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99", "locus": { "chromosome": "9", "start_pos": 69325864, "end_pos": 69202911, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000051600", "url": "https://www.ensembl.org/id/ENSBTAG00000051600" } ] } } ], "crossref": [ { "id": "ENSBTAG00000051600", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000051600", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613606", "url": "https://www.ncbi.nlm.nih.gov/gene/613606", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019511", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019511", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MDW0", "url": "https://www.orthodb.org/?gene=A0A3Q1MDW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15934", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15934", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15934:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15934:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010806853", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010806853", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDW0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVU0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVU0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY18", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY18-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPM0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPM0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQR0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQR0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS35-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NW99", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NW99-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R473", "url": "https://www.uniprot.org/uniprotkb/F6R473", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R473-1", "url": "https://www.uniprot.org/uniprotkb/F6R473-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLLRGLRLWGLGASAGLVAAARAPGASRYHRPLPRPRAPRASPPPRLRPLLALSPWSQRPAVVACGDPSPANAACMELPGAGVNSNECESVSSKQEMSEEFEANTMDFLVDLPFATIDIKDDSEITDVPKVNLERSKENECNNKEQIKKRKKKRKDYQPNYFLSIPITNKEITKGIKILQNAIIRQDEQLARAMSSDGSFHITLLVMQLLNEDDVNVGIDALLELKPFVEEILQGKPLTLPFEGVDTFGNQVGFVKLAEGDHINSLLEIADAAKRTFQEKGILAGESRTFKPHLTFMKLSRLPWLRKKGVKKIDPKLYEKFIGHRFGEEVVHCIDLCSMLKKKQSNGYYHCESSIVIGDKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGDGSSVKTEEADRNGTDSDNRK", "length": 422, "header": "tr|A0ABI0NW99-1|A0ABI0NW99_BOVIN Isoform 1 of A-kinase anchoring protein 7 OS=Bos taurus OX=9913 GN=AKAP7 PE=4 SV=1 CANONICAL=A0ABI0NW99-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MDW0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99/entry#A0A3Q1MDW0-1", "sequence": { "sequence": "GLLVVCSPLPFLETYLQSRAAHVALISGRELPVLSELGERRAASFPESQSRFPESQPRISCVGLGPGEVEPACSQRLREPPRRRASPPPLSLLLCCSAEWRRQGVLADRGVNCGCSLGSPGRTPGGRESASAMGQLCCFPFSRDEEKISELESPSSVVLQRYRREGPSWPSGDKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGDGSSVKTEEADRNGTDSDNRK", "length": 235, "header": "tr|A0A3Q1MDW0-1|A0ABI0NW99_BOVIN Computationally mapped isoform of A-kinase anchoring protein 7 OS=Bos taurus OX=9913 GN=AKAP7 PE=4 SV=2 CANONICAL=A0ABI0NW99-1" }, "locus": { "chromosome": "9", "start_pos": 69323978, "end_pos": 69291596, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083692.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083692.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067041.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067041.2" } ] } }, { "isoform_ac": "A0AAA9SVU0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99/entry#A0AAA9SVU0-1", "sequence": { "sequence": "MQLLRGLRLWGLGASAGLVAAARAPGASRYHRPLPRPRAPRASPPPRLRPLLALSPWSQRPAVVACGDPSPANAACMELPGAGVNSNECESVSSKQEMSEEFEANTMDFLVDLPFATIDIKDDSEITDVPKVNLERSKENECNNKEQIKKRKKKRKDYQPNYFLSIPITNKEITKGIKILQNAIIRQDEQLARAMSSDGSFHITLLVMQLLNEDDVNVGIDALLELKPFVEEILQGKPLTLPFEGVDTFGNQVGFVKLAEGDHINSLLEIADAAKRTFQEKGILAGESRTFKPHLTFMKLSRLPWLRKKGVKKIDPKLYEKFIGHRFGEEVVHCIDLCSMLKKKQSNGYYHCESSIVIGELESPSSVVLQRYRREGPSWPSVAGFLKAGSMPVTVWPER", "length": 399, "header": "tr|A0AAA9SVU0-1|A0ABI0NW99_BOVIN Computationally mapped isoform of A-kinase anchoring protein 7 OS=Bos taurus OX=9913 GN=AKAP7 PE=4 SV=1 CANONICAL=A0ABI0NW99-1" }, "locus": { "chromosome": "9", "start_pos": 69306187, "end_pos": 69203072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107695.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107695.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088314.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088314.1" } ] } }, { "isoform_ac": "A0AAA9SY18-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99/entry#A0AAA9SY18-1", "sequence": { "sequence": "MSEEFEANTMDFLVDLPFATIDIKDDSEITDVPKVNLERSKENECNNKEQIKKRKKKRKDYQPNYFLSIPITNKEITKGIKILQNAIIRQDEQLARAMSSDGSFHITLLVMQLLNEDDVNVGIDALLELKPFVEEILQGKPLTLPFEGVDTFGNQVGFVKLAEGDHINSLLEIADAAKRTFQEKGILAGESRTFKPHLTFMKLSRLPWLRKKGVKKIDPKLYEKFIGHRFGEEVVHCIDLCSMLKKKQSNGYYHCESSIVIGDKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGDGSSVKTEEADRNGTDSDNRK", "length": 325, "header": "tr|A0AAA9SY18-1|A0ABI0NW99_BOVIN Computationally mapped isoform of A-kinase anchoring protein 7 OS=Bos taurus OX=9913 GN=AKAP7 PE=4 SV=2 CANONICAL=A0ABI0NW99-1" }, "locus": { "chromosome": "9", "start_pos": 69323978, "end_pos": 69210757, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112576.2", "url": "https://www.ensembl.org/id/ENSBTAT00000112576.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088212.2", "url": "https://www.ensembl.org/id/ENSBTAP00000088212.2" } ] } }, { "isoform_ac": "A0AAA9TPM0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99/entry#A0AAA9TPM0-1", "sequence": { "sequence": "MQLLRGLRLWGLGASAGLVAAARAPGASRYHRPLPRPRAPRASPPPRLRPLLALSPWSQRPAVVACGDPSPANAACMELPGAGVNSNECESVSSKQEMSEEFEANTMDFLVDLPFATIDIKDDSEITDVPKVNLERSKENECNNKEQIKKRKKKRKDYQPNYFLSIPITNKEITKGIKILQNAIIRQDEQLARAMSSDGSFHITLLVMQLLNEDDVNVGIDALLELKPFVEEILQGKPLTLPFEGVDTFGNQVGFVKLAEGDHINSLLEIADAAKRTFQEKGILAGESRTFKPHLTFMKLSRLPWLRKKGVKKIDPKLYEKFIGHRFGEEVVHCIDLCSMLKKKQSNGYYHCESSIVIGIFLTQESNWGLLHSRWILYQLSYLGCCISEGLLSIRQ", "length": 396, "header": "tr|A0AAA9TPM0-1|A0ABI0NW99_BOVIN Computationally mapped isoform of A-kinase anchoring protein 7 OS=Bos taurus OX=9913 GN=AKAP7 PE=4 SV=1 CANONICAL=A0ABI0NW99-1" }, "locus": { "chromosome": "9", "start_pos": 69302197, "end_pos": 69203072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134651.1", "url": "https://www.ensembl.org/id/ENSBTAT00000134651.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098318.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098318.1" } ] } }, { "isoform_ac": "A0AAA9TQR0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99/entry#A0AAA9TQR0-1", "sequence": { "sequence": "MELPGAGVNSNECESVSSKQEMSEEFEANTMDFLVDLPFATIDIKDDSEITDVPKVNLERSKENECNNKEQIKKRKKKRKDYQPNYFLSIPITNKEITKGIKILQNAIIRQDEQLARAMSSDGSFHITLLVMQLLNEDDVNVGIDALLELKPFVEEILQGKPLTLPFEGVDTFGNQVGFVKLAEGDHINSLLEIADAAKRTFQEKGILAGESRTFKPHLTFMKLSRLPWLRKKGVKKIDPKLYEKFIGHRFGEEVVHCIDLCSMLKKKQSNGYYHCESSIVIGELESPSSVVLQRYRREGPSWPSGDKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGDGSSVKTEEADRNGTDSDNRK", "length": 369, "header": "tr|A0AAA9TQR0-1|A0ABI0NW99_BOVIN Computationally mapped isoform of A-kinase anchoring protein 7 OS=Bos taurus OX=9913 GN=AKAP7 PE=4 SV=2 CANONICAL=A0ABI0NW99-1" }, "locus": { "chromosome": "9", "start_pos": 69323978, "end_pos": 69203300, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118772.2", "url": "https://www.ensembl.org/id/ENSBTAT00000118772.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098760.2", "url": "https://www.ensembl.org/id/ENSBTAP00000098760.2" } ] } }, { "isoform_ac": "A0AAA9TS35-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99/entry#A0AAA9TS35-1", "sequence": { "sequence": "MSRKIDTLHSKPGKFSSSPTAFSFQLPVNGCELESPSSVVLQRYRREGPSWPSGDKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGDGSSVKTEEADRNGTDSDNRK", "length": 117, "header": "tr|A0AAA9TS35-1|A0ABI0NW99_BOVIN Computationally mapped isoform of A-kinase anchoring protein 7 OS=Bos taurus OX=9913 GN=AKAP7 PE=4 SV=1 CANONICAL=A0ABI0NW99-1" }, "locus": { "chromosome": "9", "start_pos": 69323978, "end_pos": 69290832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106719.1", "url": "https://www.ensembl.org/id/ENSBTAT00000106719.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101192.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101192.1" } ] } }, { "isoform_ac": "A0ABI0NW99-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99/entry#A0ABI0NW99-1", "sequence": { "sequence": "MQLLRGLRLWGLGASAGLVAAARAPGASRYHRPLPRPRAPRASPPPRLRPLLALSPWSQRPAVVACGDPSPANAACMELPGAGVNSNECESVSSKQEMSEEFEANTMDFLVDLPFATIDIKDDSEITDVPKVNLERSKENECNNKEQIKKRKKKRKDYQPNYFLSIPITNKEITKGIKILQNAIIRQDEQLARAMSSDGSFHITLLVMQLLNEDDVNVGIDALLELKPFVEEILQGKPLTLPFEGVDTFGNQVGFVKLAEGDHINSLLEIADAAKRTFQEKGILAGESRTFKPHLTFMKLSRLPWLRKKGVKKIDPKLYEKFIGHRFGEEVVHCIDLCSMLKKKQSNGYYHCESSIVIGDKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGDGSSVKTEEADRNGTDSDNRK", "length": 422, "header": "tr|A0ABI0NW99-1|A0ABI0NW99_BOVIN Isoform 1 of A-kinase anchoring protein 7 OS=Bos taurus OX=9913 GN=AKAP7 PE=4 SV=1 CANONICAL=A0ABI0NW99-1" }, "locus": { "chromosome": "9", "start_pos": 69323978, "end_pos": 69203072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145823.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145823.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105202.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105202.1" } ] } }, { "isoform_ac": "F6R473-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99/entry#F6R473-1", "sequence": { "sequence": "MGQLCCFPFSRDEEKISDKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGDGSSVKTEEADRNGTDSDNRK", "length": 80, "header": "tr|F6R473-1|A0ABI0NW99_BOVIN Computationally mapped isoform of A-kinase anchoring protein 7 OS=Bos taurus OX=9913 GN=AKAP7 PE=4 SV=2 CANONICAL=A0ABI0NW99-1" }, "locus": { "chromosome": "9", "start_pos": 69323978, "end_pos": 69291992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000294.7", "url": "https://www.ensembl.org/id/ENSBTAT00000000294.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000294.6", "url": "https://www.ensembl.org/id/ENSBTAP00000000294.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW99", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW99", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW99", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein kinase A regulatory subunit binding", "id": "GO:0034237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034237", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW99", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99" } ], "pmid": "" }, { "name": "protein kinase A binding", "id": "GO:0051018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051018", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW99", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NW99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99" }, { "id": "PF10470", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10470" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "A-kinase anchor protein 7 RI-RII subunit-binding", "eco_id": "ECO_0000259", "start_pos": 364, "end_pos": 420, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NW99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW99" }, { "id": "PF10469", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10469" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "A-kinase anchor protein 7-like phosphoesterase", "eco_id": "ECO_0000259", "start_pos": 160, "end_pos": 357, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 414, "end_pos": 416 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14931:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21545", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21545", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21545:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21545:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NW44", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NW44-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEA1", "url": "https://www.uniprot.org/uniprotkb/E1BEA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEA1-1", "url": "https://www.uniprot.org/uniprotkb/E1BEA1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQILLSGVHSAAISCGFESILEGLFGPALLKDLSLFKDCEPESISDWTFDENCLFCCLRRDKVKGHLVGLDEPASGAGQEALLKQEQAKIIRFERQAEEFLNAVFCRKDSPWVSDPNIPLVAREIMQRMIQQFAAEYTSKNSSTQDPSQPNSTKNQSLPKASPVTTSPTAATAQNPVLSKLLMADQDSPLDLTVRKSQSEPSEQDGVLDLSTKKSPCAGSTSLSHSPGCSSTQGNGRPGRPSQYRPDGLRSGDGVPPRSLQDGTREGFGHSTSLKVPLARSLQISEELLSRNQLSTAASLGPSGLQNHGQHLILSREASWAKPHYEFNLSRMKFRGNGALSNISDLPFLAENSAFPKMALQAKQDGKKDVSHSSPVDLKIPQVRGMDLSWESRTGDQYSYSSLVMGSQTESALSKKLRAILPKQNRKSMLDAGPDSWGSDAEQSTSGQPYPTSDQEGDPGSKQPRKKRGRYRQYNSEILEEAISVVMSGKMSVSKAQSIYGIPHSTLEYKVKERLGTLKNPPKKKMKLMRSEGPDVSVKIELDPQGEAAQSANESKNE", "length": 558, "header": "tr|A0ABI0NW44-1|A0ABI0NW44_BOVIN Isoform 1 of Ligand dependent nuclear receptor corepressor OS=Bos taurus OX=9913 GN=LCOR PE=4 SV=1 CANONICAL=A0ABI0NW44-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NW44-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW44/entry#A0ABI0NW44-1", "sequence": { "sequence": "MQILLSGVHSAAISCGFESILEGLFGPALLKDLSLFKDCEPESISDWTFDENCLFCCLRRDKVKGHLVGLDEPASGAGQEALLKQEQAKIIRFERQAEEFLNAVFCRKDSPWVSDPNIPLVAREIMQRMIQQFAAEYTSKNSSTQDPSQPNSTKNQSLPKASPVTTSPTAATAQNPVLSKLLMADQDSPLDLTVRKSQSEPSEQDGVLDLSTKKSPCAGSTSLSHSPGCSSTQGNGRPGRPSQYRPDGLRSGDGVPPRSLQDGTREGFGHSTSLKVPLARSLQISEELLSRNQLSTAASLGPSGLQNHGQHLILSREASWAKPHYEFNLSRMKFRGNGALSNISDLPFLAENSAFPKMALQAKQDGKKDVSHSSPVDLKIPQVRGMDLSWESRTGDQYSYSSLVMGSQTESALSKKLRAILPKQNRKSMLDAGPDSWGSDAEQSTSGQPYPTSDQEGDPGSKQPRKKRGRYRQYNSEILEEAISVVMSGKMSVSKAQSIYGIPHSTLEYKVKERLGTLKNPPKKKMKLMRSEGPDVSVKIELDPQGEAAQSANESKNE", "length": 558, "header": "tr|A0ABI0NW44-1|A0ABI0NW44_BOVIN Isoform 1 of Ligand dependent nuclear receptor corepressor OS=Bos taurus OX=9913 GN=LCOR PE=4 SV=1 CANONICAL=A0ABI0NW44-1" }, "locus": { "chromosome": "26", "start_pos": 18230321, "end_pos": 18134792, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143999.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143999.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105128.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105128.1" } ] } }, { "isoform_ac": "E1BEA1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW44/entry#E1BEA1-1", "sequence": { "sequence": "MQRMIQQFAAEYTSKNSSTQDPSQPNSTKNQSLPKASPVTTSPTAATAQNPVLSKLLMADQDSPLDLTVRKSQSEPSEQDGVLDLSTKKSPCAGSTSLSHSPGCSSTQGNGRPGRPSQYRPDGLRSGDGVPPRSLQDGTREGFGHSTSLKVPLARSLQISEELLSRNQLSTAASLGPSGLQNHGQHLILSREASWAKPHYEFNLSRMKFRGNGALSNISDLPFLAENSAFPKMALQAKQDGKKDVSHSSPVDLKIPQVRGMDLSWESRTGDQYSYSSLVMGSQTESALSKKLRAILPKQNRKSMLDAGPDSWGSDAEQSTSGQPYPTSDQEGDPGSKQPRKKRGRYRQYNSEILEEAISVVMSGKMSVSKAQSIYGIPHSTLEYKVKERLGTLKNPPKKKMKLMSG", "length": 406, "header": "tr|E1BEA1-1|A0ABI0NW44_BOVIN Computationally mapped isoform of Ligand dependent nuclear receptor corepressor OS=Bos taurus OX=9913 GN=LCOR PE=4 SV=3 CANONICAL=A0ABI0NW44-1" }, "locus": { "chromosome": "26", "start_pos": 18232818, "end_pos": 18223651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005261.7", "url": "https://www.ensembl.org/id/ENSBTAT00000005261.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005261.7", "url": "https://www.ensembl.org/id/ENSBTAP00000005261.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW44", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW44" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW44", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW44" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW44", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NW44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW44" }, { "id": "PRU00320", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00320" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "H-T-H motif", "eco_id": "ECO_0000256", "start_pos": 493, "end_pos": 513, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NW44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW44" }, { "id": "PS50960", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50960" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH psq-type", "eco_id": "ECO_0000259", "start_pos": 465, "end_pos": 517, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 151, "end_pos": 153 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 342, "end_pos": 344 }, { "start_pos": 553, "end_pos": 555 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NWG2-1", "uniprot_ac": "A0ABI0NWG2", "uniprot_id": "A0ABI0NWG2_BOVIN", "mass": { "chemical_mass": 62134.0, "monoisotopic_mass": 62134.0 }, "refseq": {}, "gene_names": [ { "name": "SRSF4", "type": "recommended", "evidence": [ { "id": "A0ABI0NWG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2" } ] } ], "protein_names": [ { "name": "Serine and arginine rich splicing factor 4", "type": "synonym", "evidence": [ { "id": "A0ABI0NWG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWG2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SRSF4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2", "locus": { "chromosome": "2", "start_pos": 124400699, "end_pos": 124375055, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013309", "url": "https://www.ensembl.org/id/ENSBTAG00000013309" } ] } } ], "crossref": [ { "id": "ENSBTAG00000013309", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013309", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12337", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12337", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12600", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12600", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "614310", "url": "https://www.ncbi.nlm.nih.gov/gene/614310", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MQP8", "url": "https://www.orthodb.org/?gene=A0A3Q1MQP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48038", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48038", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48038:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48038:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MQP8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWG2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWG2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QYN9", "url": "https://www.uniprot.org/uniprotkb/F6QYN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QYN9-1", "url": "https://www.uniprot.org/uniprotkb/F6QYN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGNIPNPDQPWRGSVLASECGNGSPHWENKTHILLMLAEDCHVHIQRKACGTVLGQRYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKDKSRSRSRSADKRRSKSKDPAEEKVQNSDRTGKSKSRSPSRHKSKSRSRSQERGAEEARGSASRSRSKEKSLRKSRSRSQGGSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGGKRDSKSGSGGGSGSSKKKKKDDADRSQSRSRSRSGSKERERAKSESGQREGRGEGEDAGANQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSGSRSPSRSRSRSHSRS", "length": 548, "header": "tr|A0ABI0NWG2-1|A0ABI0NWG2_BOVIN Isoform 1 of Serine and arginine rich splicing factor 4 OS=Bos taurus OX=9913 GN=SRSF4 PE=3 SV=1 CANONICAL=A0ABI0NWG2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MQP8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2/entry#A0A3Q1MQP8-1", "sequence": { "sequence": "MLAEDCHVHIQRKACGTVLGQRYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKDKSRSRSRSADKRRSKSKDPAEEKVQNSDRTGKSKSRSPSRHKSKSRSRSQERGAEEARGSASRSRSKEKSLRKSRSRSQGGSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGGKRDSKSGSGGGSGSSKKKKKDDADRSQSRSRSRSGSKERERAKSESGQREGRGEGEDAGANQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSGSRSPSRSRSRSHSRS", "length": 479, "header": "tr|A0A3Q1MQP8-1|A0ABI0NWG2_BOVIN Computationally mapped isoform of Serine and arginine rich splicing factor 4 OS=Bos taurus OX=9913 GN=SRSF4 PE=3 SV=1 CANONICAL=A0ABI0NWG2-1" }, "locus": { "chromosome": "2", "start_pos": 124400036, "end_pos": 124386544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067183.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067183.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056714.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056714.1" } ] } }, { "isoform_ac": "A0ABI0NWG2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2/entry#A0ABI0NWG2-1", "sequence": { "sequence": "MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGNIPNPDQPWRGSVLASECGNGSPHWENKTHILLMLAEDCHVHIQRKACGTVLGQRYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKDKSRSRSRSADKRRSKSKDPAEEKVQNSDRTGKSKSRSPSRHKSKSRSRSQERGAEEARGSASRSRSKEKSLRKSRSRSQGGSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGGKRDSKSGSGGGSGSSKKKKKDDADRSQSRSRSRSGSKERERAKSESGQREGRGEGEDAGANQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSGSRSPSRSRSRSHSRS", "length": 548, "header": "tr|A0ABI0NWG2-1|A0ABI0NWG2_BOVIN Isoform 1 of Serine and arginine rich splicing factor 4 OS=Bos taurus OX=9913 GN=SRSF4 PE=3 SV=1 CANONICAL=A0ABI0NWG2-1" }, "locus": { "chromosome": "2", "start_pos": 124400036, "end_pos": 124375182, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145897.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145897.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105306.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105306.1" } ] } }, { "isoform_ac": "F6QYN9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2/entry#F6QYN9-1", "sequence": { "sequence": "MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSKHLKGICIGGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKDKSRSRSRSADKRRSKSKDPAEEKVQNSDRTGKSKSRSPSRHKSKSRSRSQERGAEEARGSASRSRSKEKSLRKSRSRSQGGSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGGKRDSKSGSGGGSGSSKKKKKDDADRSQSRSRSRSGSKERERAKSESGQREGRGEGEDAGANQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSGSRSPSRSRSRSHSRS", "length": 502, "header": "tr|F6QYN9-1|A0ABI0NWG2_BOVIN Computationally mapped isoform of Serine and arginine rich splicing factor 4 OS=Bos taurus OX=9913 GN=SRSF4 PE=3 SV=1 CANONICAL=A0ABI0NWG2-1" }, "locus": { "chromosome": "2", "start_pos": 124400036, "end_pos": 124375182, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000037984.7", "url": "https://www.ensembl.org/id/ENSBTAT00000037984.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000037803.5", "url": "https://www.ensembl.org/id/ENSBTAP00000037803.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWG2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWG2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWG2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWG2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWG2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NWG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG2" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 127, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NXQ6-1", "uniprot_ac": "A0ABI0NXQ6", "uniprot_id": "A0ABI0NXQ6_BOVIN", "mass": { "chemical_mass": 25597.0, "monoisotopic_mass": 25597.0 }, "refseq": { "ac": "XP_005207391", "name": "synaptogyrin-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207391" }, "gene_names": [ { "name": "SYNGR1", "type": "recommended", "evidence": [ { "id": "A0ABI0NXQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ6" } ] }, { "name": "SYNGR1", "type": "synonym", "evidence": [ { "id": "XP_005207391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207391" } ] } ], "protein_names": [ { "name": "Synaptogyrin", "type": "recommended", "evidence": [ { "id": "A0ABI0NXQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ6/entry#names_and_taxonomy" } ] }, { "name": "synaptogyrin-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005207391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207391" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXQ6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SYNGR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ6", "locus": { "chromosome": "5", "start_pos": 110805984, "end_pos": 110778235, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005765", "url": "https://www.ensembl.org/id/ENSBTAG00000005765" } ] } } ], "crossref": [ { "id": "ENSBTAG00000005765", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005765", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "534995", "url": "https://www.ncbi.nlm.nih.gov/gene/534995", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NHB1", "url": "https://www.orthodb.org/?gene=A0A3Q1NHB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10838", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10838", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10838:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10838:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005207391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207391", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1NHB1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NHB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NHB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NHB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZP7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZP7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXQ6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWVFSIVVFGSIVNEGYLNSPSESEEFCIYNRNPNACGYGVTVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCFLANQWQVSEPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSALFSQDYMDPSQDSSMPYAPYVEPSTGPEPTSMGGTYQQPASAFEPEPQGYQSQGY", "length": 234, "header": "tr|A0ABI0NXQ6-1|A0ABI0NXQ6_BOVIN Isoform 1 of Synaptogyrin OS=Bos taurus OX=9913 GN=SYNGR1 PE=3 SV=1 CANONICAL=A0ABI0NXQ6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NHB1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ6/entry#A0A3Q1NHB1-1", "sequence": { "sequence": "MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWVFSIVVFGSIVNEGYLNSPSESEEFCIYNRNPNACGYGVTVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCFLANQWQVSEPKDNPLNEGTDAARAAIAFSFFSIFTWISRVIWASF", "length": 170, "header": "tr|A0A3Q1NHB1-1|A0ABI0NXQ6_BOVIN Computationally mapped isoform of Synaptogyrin OS=Bos taurus OX=9913 GN=SYNGR1 PE=3 SV=2 CANONICAL=A0ABI0NXQ6-1" }, "locus": { "chromosome": "5", "start_pos": 110801651, "end_pos": 110778266, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080189.3", "url": "https://www.ensembl.org/id/ENSBTAT00000080189.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071328.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071328.2" } ] } }, { "isoform_ac": "A0AAA9SZP7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ6/entry#A0AAA9SZP7-1", "sequence": { "sequence": "MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWVFSIVVFGSIVNEGYLNSPSESEEFCIYNRNPNACGYGVTVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAWETRP", "length": 118, "header": "tr|A0AAA9SZP7-1|A0ABI0NXQ6_BOVIN Computationally mapped isoform of Synaptogyrin OS=Bos taurus OX=9913 GN=SYNGR1 PE=3 SV=1 CANONICAL=A0ABI0NXQ6-1" }, "locus": { "chromosome": "5", "start_pos": 110800519, "end_pos": 110778266, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113900.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113900.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089766.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089766.1" } ] } }, { "isoform_ac": "A0ABI0NXQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ6/entry#A0ABI0NXQ6-1", "sequence": { "sequence": "MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWVFSIVVFGSIVNEGYLNSPSESEEFCIYNRNPNACGYGVTVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCFLANQWQVSEPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSALFSQDYMDPSQDSSMPYAPYVEPSTGPEPTSMGGTYQQPASAFEPEPQGYQSQGY", "length": 234, "header": "tr|A0ABI0NXQ6-1|A0ABI0NXQ6_BOVIN Isoform 1 of Synaptogyrin OS=Bos taurus OX=9913 GN=SYNGR1 PE=3 SV=1 CANONICAL=A0ABI0NXQ6-1" }, "locus": { "chromosome": "5", "start_pos": 110804980, "end_pos": 110778266, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129511.2", "url": "https://www.ensembl.org/id/ENSBTAT00000129511.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106091.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106091.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXQ6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ6" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXQ6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXQ6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NXQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXQ6" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 173, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NV47-1", "uniprot_ac": "A0ABI0NV47", "uniprot_id": "A0ABI0NV47_BOVIN", "mass": { "chemical_mass": 82264.0, "monoisotopic_mass": 82264.0 }, "refseq": { "ac": "NP_001421745", "name": "serine/threonine-protein kinase DCLK1 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421745" }, "gene_names": [ { "name": "DCLK1", "type": "recommended", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "name": "DCLK1", "type": "synonym", "evidence": [ { "id": "NP_001421745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421745" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein kinase DCLK1", "type": "recommended", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47/entry#names_and_taxonomy" } ] }, { "name": "Doublecortin-like and CAM kinase-like 1", "type": "synonym", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47/entry#names_and_taxonomy" } ] }, { "name": "Doublecortin-like kinase 1", "type": "synonym", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase DCLK1 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001421745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421745" } ] } ], "function": [ { "annotation": "Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system.", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPE7", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPE7#function" }, { "database": "UniProtKB", "id": "ARBA00056871", "url": "https://www.uniprot.org/uniprotkb/ARBA00056871#function" }, { "database": "UniProtKB", "id": "A0ABI0NV47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47#function" }, { "database": "UniProtKB", "id": "F1MDA8", "url": "https://www.uniprot.org/uniprotkb/F1MDA8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DCLK1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000038495", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038495", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000053984", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000053984", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14183", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14183", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17069", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17069", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17140", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17140", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "613449", "url": "https://www.ncbi.nlm.nih.gov/gene/613449", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036572", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036572", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03607", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03607", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001421745", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421745", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3S5ZPE7", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3S5ZPE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8H8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8H8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8H8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NV47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NV47-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MDA8", "url": "https://www.uniprot.org/uniprotkb/F1MDA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MDA8-1", "url": "https://www.uniprot.org/uniprotkb/F1MDA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLLEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTKVCSSMDENDGPGEGEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNPDVRSRYKAQPAPPELNSESEDYSPSSSETVRSPNSPF", "length": 741, "header": "tr|A0ABI0NV47-1|A0ABI0NV47_BOVIN Isoform 1 of Serine/threonine-protein kinase DCLK1 OS=Bos taurus OX=9913 GN=DCLK1 PE=3 SV=1 CANONICAL=A0ABI0NV47-1" }, "isoforms": [ { "isoform_ac": "A0A3S5ZPE7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47/entry#A0A3S5ZPE7-1", "sequence": { "sequence": "MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLLEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTKVCSSMDENDGPGEGEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIAFPCL", "length": 691, "header": "tr|A0A3S5ZPE7-1|A0ABI0NV47_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase DCLK1 OS=Bos taurus OX=9913 GN=DCLK1 PE=3 SV=3 CANONICAL=A0ABI0NV47-1" }, "locus": { "chromosome": "12", "start_pos": 25680488, "end_pos": 25346719, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054446.5", "url": "https://www.ensembl.org/id/ENSBTAT00000054446.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050463.5", "url": "https://www.ensembl.org/id/ENSBTAP00000050463.5" } ] } }, { "isoform_ac": "A0AAA9T8H8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47/entry#A0AAA9T8H8-1", "sequence": { "sequence": "MLELIEVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNPDVRSRYKAQPAPPELNSESEDYSPSSSETVRSPNSPF", "length": 433, "header": "tr|A0AAA9T8H8-1|A0ABI0NV47_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase DCLK1 OS=Bos taurus OX=9913 GN=DCLK1 PE=3 SV=2 CANONICAL=A0ABI0NV47-1" }, "locus": { "chromosome": "12", "start_pos": 25689325, "end_pos": 25608721, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119249.2", "url": "https://www.ensembl.org/id/ENSBTAT00000119249.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093110.2", "url": "https://www.ensembl.org/id/ENSBTAP00000093110.2" } ] } }, { "isoform_ac": "A0ABI0NV47-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47/entry#A0ABI0NV47-1", "sequence": { "sequence": "MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLLEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTKVCSSMDENDGPGEGEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNPDVRSRYKAQPAPPELNSESEDYSPSSSETVRSPNSPF", "length": 741, "header": "tr|A0ABI0NV47-1|A0ABI0NV47_BOVIN Isoform 1 of Serine/threonine-protein kinase DCLK1 OS=Bos taurus OX=9913 GN=DCLK1 PE=3 SV=1 CANONICAL=A0ABI0NV47-1" }, "locus": { "chromosome": "12", "start_pos": 25689325, "end_pos": 25346719, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141273.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141273.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104064.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104064.1" } ] } }, { "isoform_ac": "F1MDA8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47/entry#F1MDA8-1", "sequence": { "sequence": "MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLLEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQQPGMYWIRPPLLIRRGRFSDEDATRM", "length": 729, "header": "tr|F1MDA8-1|A0ABI0NV47_BOVIN Computationally mapped isoform of Serine/threonine-protein kinase DCLK1 OS=Bos taurus OX=9913 GN=DCLK1 PE=3 SV=5 CANONICAL=A0ABI0NV47-1" }, "locus": { "chromosome": "12", "start_pos": 25689218, "end_pos": 25346719, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061628.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061628.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053753.5", "url": "https://www.ensembl.org/id/ENSBTAP00000053753.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ], "pmid": "" }, { "name": "axon extension", "id": "GO:0048675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048675", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV47", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 616, "end_pos": 618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 677, "end_pos": 679, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": 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"uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": 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"database": "Ensembl Peptide", "id": "ENSBTAP00000076853.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076853.1" } ] } }, { "isoform_ac": "A0ABI0NVA0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVA0/entry#A0ABI0NVA0-1", "sequence": { "sequence": "MESCGMLSLLLHAMVLGLPSTWAAEDTCVNACPAACVCSSVERRCSVRCDRAGLLRVPAEFPCEAASIDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELSLAHNGDLRYLHARTFTALGRLRRLDLTVCRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLERSRIEAVASSSLLGLRRLRSLSLQGNRVRAVHGGAFRDCSALEHLLLNDNLLAALPADAFLGLRRLRTLNLGGNALGRVVRAWFAELAELELLYLDRNRIAFVEEGAFQNLSGLLALHLNGNHLTVLAWAAFQPGFFLGRLFLFRNPWRCDCRLEWLRDWMESFGRTADVPCASPGSVAGLDLRQVAFGRSSEGFCVDPDELNLTASSPGPSPEPAATTVSRFSSLLSKLLAPRAPVAEAANTTKEGPVNTSLSDSFPSLGVGGSGYKTPFLVGSGLLLSVAQHVLFVLQRD", "length": 483, "header": "tr|A0ABI0NVA0-1|A0ABI0NVA0_BOVIN Isoform 1 of Nyctalopin OS=Bos taurus OX=9913 GN=NYX PE=3 SV=1 CANONICAL=A0ABI0NVA0-1" }, "locus": { "chromosome": "X", "start_pos": 102130819, "end_pos": 102109903, "strand": "+", "evidence": [ 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37342:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37342:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S3I0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3I0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3I0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUJ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1T7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1T7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1T7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1T7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P879", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P879", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P879-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P879-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF89", "url": "https://www.uniprot.org/uniprotkb/E1BF89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF89-1", "url": "https://www.uniprot.org/uniprotkb/E1BF89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKHFYNSEISYRHKTSRNIKNPREGGVKCLLLPFFPSFHILHVWLFLPLMTVVIVVSFDHCSLYTSHLAEYFTSIFLVNFYSNAMRFKGFPGGSEVKASACNAETWVQSLGQKDPLEKGMATHSSILAWRIPWTEELGGLQFTGLQSRTRLSNFTFMRSCTSTLQRKKKIGSQARRTLRRQQQQPQHEWWRQLNDTKDHDTMGHTYEQVLRQPVSQERSRQSLRSEEGSLYYADIQLYRLPQPRSVQEVKHLQLKNATEYATLRFPQVTPRYDSKNGTLV", "length": 280, "header": "tr|A0ABI0NUJ0-1|A0ABI0NUJ0_BOVIN Isoform 1 of Chromosome 15 C11orf52 homolog OS=Bos taurus OX=9913 GN=C15H11orf52 PE=4 SV=1 CANONICAL=A0ABI0NUJ0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S3I0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUJ0/entry#A0AAA9S3I0-1", "sequence": { "sequence": "MGNQLCCGRSCNAMRFKGFPGGSEVKASACNAETWVQSLGQKDPLEKGMATHSSILAWRIPWTEELGGLQFTGLQSRTRLSNFTFMRSCTSTLQRKKKIGSQARRTLRRQQQQPQHEWWRQLNDTKDHDTMGHTYEQVLRQPVSQERSRQSLRSEEGSLYYADIQLYRLPQPRSVQEVKHLQLKNATEYATLRFPQVTPRYDSKNGTLV", "length": 209, "header": "tr|A0AAA9S3I0-1|A0ABI0NUJ0_BOVIN Computationally mapped isoform of Chromosome 15 C11orf52 homolog OS=Bos taurus OX=9913 GN=C15H11orf52 PE=4 SV=1 CANONICAL=A0ABI0NUJ0-1" }, "locus": { "chromosome": "15", "start_pos": 22257681, "end_pos": 22251417, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118511.2", "url": "https://www.ensembl.org/id/ENSBTAT00000118511.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077823.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077823.1" } ] } }, { "isoform_ac": "A0ABI0NUJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUJ0/entry#A0ABI0NUJ0-1", "sequence": { "sequence": "MKHFYNSEISYRHKTSRNIKNPREGGVKCLLLPFFPSFHILHVWLFLPLMTVVIVVSFDHCSLYTSHLAEYFTSIFLVNFYSNAMRFKGFPGGSEVKASACNAETWVQSLGQKDPLEKGMATHSSILAWRIPWTEELGGLQFTGLQSRTRLSNFTFMRSCTSTLQRKKKIGSQARRTLRRQQQQPQHEWWRQLNDTKDHDTMGHTYEQVLRQPVSQERSRQSLRSEEGSLYYADIQLYRLPQPRSVQEVKHLQLKNATEYATLRFPQVTPRYDSKNGTLV", "length": 280, "header": "tr|A0ABI0NUJ0-1|A0ABI0NUJ0_BOVIN Isoform 1 of Chromosome 15 C11orf52 homolog OS=Bos taurus OX=9913 GN=C15H11orf52 PE=4 SV=1 CANONICAL=A0ABI0NUJ0-1" }, "locus": { "chromosome": "15", "start_pos": 22257681, "end_pos": 22253240, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153910.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153910.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107543.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107543.1" } ] } }, { "isoform_ac": "A0ABI0P1T7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUJ0/entry#A0ABI0P1T7-1", "sequence": { "sequence": "MGNQLCCGRSWSCTSTLQRKKKIGSQARRTLRRQQQQPQHEWWRQLNDTKDHDTMGHTYEQVLRQPVSQERSRQSLRSEEGSLYYADIQLYRLPQPRSVQEVKHLQLKNATEYATLRFPQVTPRYDSKNGTLV", "length": 133, "header": "tr|A0ABI0P1T7-1|A0ABI0P1T7_BOVIN Computationally mapped isoform of Chromosome 15 C11orf52 homolog OS=Bos taurus OX=9913 GN=C15H11orf52 PE=4 SV=1 CANONICAL=A0ABI0NUJ0-1" }, "locus": { "chromosome": "15", "start_pos": 22257681, "end_pos": 22251417, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144749.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144749.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104403.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104403.1" } ] } }, { "isoform_ac": "A0ABI0P879-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUJ0/entry#A0ABI0P879-1", "sequence": { "sequence": "MRRTEMECNAMRFKGFPGGSEVKASACNAETWVQSLGQKDPLEKGMATHSSILAWRIPWTEELGGLQFTGLQSRTRLSNFTFMRSCTSTLQRKKKIGSQARRTLRRQQQQPQHEWWRQLNDTKDHDTMGHTYEQVLRQPVSQERSRQSLRSEEGSLYYADIQLYRLPQPRSVQEVKHLQLKNATEYATLRFPQVTPRYDSKNGTLV", "length": 206, "header": "tr|A0ABI0P879-1|A0ABI0P879_BOVIN Computationally mapped isoform of Chromosome 15 C11orf52 homolog OS=Bos taurus OX=9913 GN=C15H11orf52 PE=4 SV=1 CANONICAL=A0ABI0NUJ0-1" }, "locus": { "chromosome": "15", "start_pos": 22257681, "end_pos": 22251650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136314.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136314.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107574.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107574.1" } ] } }, { "isoform_ac": "E1BF89-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUJ0/entry#E1BF89-1", "sequence": { "sequence": "MRRTEMEWSCTSTLQRKKKIGSQARRTLRRQQQQPQHEWWRQLNDTKDHDTMGHTYEQVLRQPVSQERSRQSLRSEEGSLYYADIQLYRLPQPRSVQEVKHLQLKNATEYATLRFPQVTPRYDSKNGTLV", "length": 130, "header": "tr|E1BF89-1|A0ABI0NUJ0_BOVIN Computationally mapped isoform of Chromosome 15 C11orf52 homolog OS=Bos taurus OX=9913 GN=C15H11orf52 PE=4 SV=2 CANONICAL=A0ABI0NUJ0-1" }, "locus": { "chromosome": "15", "start_pos": 22257681, "end_pos": 22251650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011420.7", "url": "https://www.ensembl.org/id/ENSBTAT00000011420.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011420.5", "url": "https://www.ensembl.org/id/ENSBTAP00000011420.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614490", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614490", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SMA8-1", "protein_name": "Chromosome 9 C11orf52 homolog", "gene_name": "C9H11orf52", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNRLCCGGSWSCPSTFQRKKKMGSQARWTLKQQQQQEQQQQQQQQQQQQLRQNGLKGHDIRRRTHEQVLKQPAPQRRSQGLRLEESSLHYADIQVCSRTQPRSAQEMKHLQLENATEYAILHFPQAKPRYDSKNGTLV", "length": 139 }, "evidence": [ { "id": "A0ABI0NUJ0", "url": "https://omabrowser.org/oma/group/A0ABI0NUJ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q96A22-1", "protein_name": "Uncharacterized protein C11orf52", "gene_name": "C11orf52", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNRVCCGGSWSCPSTFQKKKKTGSQTRRTLKPQPQQLQQNLPKGHETTGHTYERVLQQQGSQERSPGLMSEDSNLHYADIQVCSRPHAREVKHVHLENATEYATLRFPQATPRYDSKNGTLV", "length": 123 }, "evidence": [ { "id": "A0ABI0NUJ0", "url": "https://omabrowser.org/oma/group/A0ABI0NUJ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D8L0-1", "protein_name": "Uncharacterized protein C11orf52 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNRLCCGGTWSCPSTFQKKSKTGSHPRPTLSILKQQQLWQNGTKDYETTAPTYEQVLYPPASQKKTSNSTSEESDLHYADIHVLRQIRPHSLHTVKCLHSESATEYATLRFPQATPQYDSNNGTLV", "length": 127 }, "evidence": [ { "id": "A0ABI0NUJ0", "url": "https://omabrowser.org/oma/group/A0ABI0NUJ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 276, "end_pos": 278 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NZW7-1", "uniprot_ac": "A0ABI0NZW7", "uniprot_id": "A0ABI0NZW7_BOVIN", "mass": { "chemical_mass": 45205.0, "monoisotopic_mass": 45205.0 }, "refseq": {}, "gene_names": [ { "name": "HERPUD1", "type": "recommended", "evidence": [ { "id": "A0ABI0NZW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZW7" } ] } ], "protein_names": [ { "name": "Homocysteine inducible ER protein with ubiquitin like domain 1", "type": "synonym", "evidence": [ { "id": "A0ABI0NZW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZW7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZW7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZW7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HERPUD1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZW7", "locus": { "chromosome": "18", "start_pos": 24977382, "end_pos": 24966368, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016896", "url": "https://www.ensembl.org/id/ENSBTAG00000016896" } ] } } ], "crossref": [ { "id": "ENSBTAG00000016896", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016896", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "613577", "url": "https://www.ncbi.nlm.nih.gov/gene/613577", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12943", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12943", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12943:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12943:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NPY2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPY2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ34", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ34-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZW7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZW7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P128", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P128", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P128-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P128-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MMX9", "url": "https://www.uniprot.org/uniprotkb/F1MMX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MMX9-1", "url": "https://www.uniprot.org/uniprotkb/F1MMX9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPEPEPVTLLVKSPNQRHRDLELSADRSWSVGRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVMHLVCNVKSTSKMPEAGAKQYILKHLNILKEILQVAESTEQPTGLNQGQSPGDSSSDGLRQREVLRNPSPSGWESISRPEAAQPAFQGLGPGFSGYTTYGWLQLSWFQQMYARQYYMQYLAATAASGAFVPAPSAQEIPVVTAPTPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPNDGGPQEAVNQDPNNNFQGDPDPESEDPSHLPPDRDVRGDEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "length": 404, "header": "tr|A0ABI0NZW7-1|A0ABI0NZW7_BOVIN Isoform 1 of Homocysteine inducible ER protein with ubiquitin like domain 1 OS=Bos taurus OX=9913 GN=HERPUD1 PE=4 SV=1 CANONICAL=A0ABI0NZW7-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NPY2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZW7/entry#A0ABI0NPY2-1", "sequence": { "sequence": "MEPEPEPVTLLVKSPNQRHRDLELSADRSWSVGRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKVAESTEQPTGLNQGQSPGDSSSDGLRQREVLRNPSPSGWESISRPEAAQPAFQGLGPGFSGYTTYGWLQLSWFQQMYARQYYMQYLAATAASGAFVPAPSAQEIPVVTAPTPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPNDGGPQEAVNQDPNNNFQGDPDPESEDPSHLPPDRDVRGDEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "length": 364, "header": "tr|A0ABI0NPY2-1|A0ABI0NZW7_BOVIN Computationally mapped isoform of Homocysteine inducible ER protein with ubiquitin like domain 1 OS=Bos taurus OX=9913 GN=HERPUD1 PE=4 SV=1 CANONICAL=A0ABI0NZW7-1" }, "locus": { "chromosome": "18", "start_pos": 24977191, "end_pos": 24966730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149742.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149742.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105232.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105232.1" } ] } }, { "isoform_ac": "A0ABI0NZ34-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZW7/entry#A0ABI0NZ34-1", "sequence": { "sequence": "MGQVVFAPCCQEGGSRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVMHLVCNVKSTSKMPEAGAKVAESTEQPTGLNQGQSPGDSSSDGLRQREVLRNPSPSGWESISRPEAAQPAFQGLGPGFSGYTTYGWLQLSWFQQMYARQYYMQYLAATAASGAFVPAPSAQEIPVVTAPTPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPNDGGPQEAVNQDPNNNFQGDPDPESEDPSHLPPDRDVRGDEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "length": 357, "header": "tr|A0ABI0NZ34-1|A0ABI0NZ34_BOVIN Computationally mapped isoform of Homocysteine inducible ER protein with ubiquitin like domain 1 OS=Bos taurus OX=9913 GN=HERPUD1 PE=4 SV=1 CANONICAL=A0ABI0NZW7-1" }, "locus": { "chromosome": "18", "start_pos": 24977191, "end_pos": 24968053, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150582.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150582.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105661.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105661.1" } ] } }, { "isoform_ac": "A0ABI0NZW7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZW7/entry#A0ABI0NZW7-1", "sequence": { "sequence": "MEPEPEPVTLLVKSPNQRHRDLELSADRSWSVGRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVMHLVCNVKSTSKMPEAGAKQYILKHLNILKEILQVAESTEQPTGLNQGQSPGDSSSDGLRQREVLRNPSPSGWESISRPEAAQPAFQGLGPGFSGYTTYGWLQLSWFQQMYARQYYMQYLAATAASGAFVPAPSAQEIPVVTAPTPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPNDGGPQEAVNQDPNNNFQGDPDPESEDPSHLPPDRDVRGDEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "length": 404, "header": "tr|A0ABI0NZW7-1|A0ABI0NZW7_BOVIN Isoform 1 of Homocysteine inducible ER protein with ubiquitin like domain 1 OS=Bos taurus OX=9913 GN=HERPUD1 PE=4 SV=1 CANONICAL=A0ABI0NZW7-1" }, "locus": { "chromosome": "18", "start_pos": 24977191, "end_pos": 24966730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140183.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140183.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104011.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104011.1" } ] } }, { "isoform_ac": "A0ABI0P128-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZW7/entry#A0ABI0P128-1", "sequence": { "sequence": "MEPEPEPVTLLVKSPNQRHRDLELSADRSWSVGRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKEKRHVMHLVCNVKSTSKMPEAGAKVAESTEQPTGLNQGQSPGDSSSDGLRQREVLRNPSPSGWESISRHHVGWFPFRQRPVQNFPNDGGPQEAVNQDPNNNFQGDPDPESEDPSHLPPDRDVRGDEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "length": 230, "header": "tr|A0ABI0P128-1|A0ABI0P128_BOVIN Computationally mapped isoform of Homocysteine inducible ER protein with ubiquitin like domain 1 OS=Bos taurus OX=9913 GN=HERPUD1 PE=4 SV=1 CANONICAL=A0ABI0NZW7-1" }, "locus": { "chromosome": "18", "start_pos": 24977191, "end_pos": 24966730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137595.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137595.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104593.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104593.1" } ] } }, { "isoform_ac": "F1MMX9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZW7/entry#F1MMX9-1", "sequence": { "sequence": "MGQVVFAPCCQEGGSRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVMHLVCNVKSTSKMPEAGAKQYILKHLNILKEILQVAESTEQPTGLNQGQSPGDSSSDGLRQREVLRNPSPSGWESISRPEAAQPAFQGLGPGFSGYTTYGWLQLSWFQQMYARQYYMQYLAATAASGAFVPAPSAQEIPVVTAPTPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPNDGGPQEAVNQDPNNNFQGDPDPESEDPSHLPPDRDVRGDEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN", "length": 372, "header": "tr|F1MMX9-1|A0ABI0NZW7_BOVIN Computationally mapped isoform of Homocysteine inducible ER protein with ubiquitin like domain 1 OS=Bos taurus OX=9913 GN=HERPUD1 PE=4 SV=4 CANONICAL=A0ABI0NZW7-1" }, "locus": { "chromosome": "18", "start_pos": 24977191, "end_pos": 24968053, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022472.8", "url": "https://www.ensembl.org/id/ENSBTAT00000022472.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022472.7", "url": "https://www.ensembl.org/id/ENSBTAP00000022472.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZW7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZW7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZW7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZW7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NZW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZW7" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 70, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P042-1", "uniprot_ac": "A0ABI0P042", "uniprot_id": "A0ABI0P042_BOVIN", "mass": { "chemical_mass": 26234.0, "monoisotopic_mass": 26234.0 }, "refseq": {}, "gene_names": [ { "name": "RPAIN", "type": "recommended", "evidence": [ { "id": "A0ABI0P042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042" } ] } ], "protein_names": [ { "name": "RPA interacting protein", "type": "synonym", "evidence": [ { "id": "A0ABI0P042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P042", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RPAIN", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042", "locus": { "chromosome": "19", "start_pos": 26119984, "end_pos": 26127138, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000025149", "url": "https://www.ensembl.org/id/ENSBTAG00000025149" } ] } } ], "crossref": [ { "id": "IPR028155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31742:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31742:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14766", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14766", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14767", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14767", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14768", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14768", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SEC6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SEC6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3R2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3R2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3R2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3R2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6J4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6J4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6J4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAV0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAV0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P042", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P042-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QAL6", "url": "https://www.uniprot.org/uniprotkb/F6QAL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QAL6-1", "url": "https://www.uniprot.org/uniprotkb/F6QAL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAERPGSRHHSLYKLTGSPPWKEAFRQGCLERMRNSRDRLLSKYRQAGGSMSGGAQNTLLVQEVMEEEWNALQSVESWPQAWAQLEEPMDLAVLEEIQQELIDQEQSIISEYEKSLQFDEQCLSVMLAEWEANPLICPVCTKYNLRIAGGLVVCQCGLYIQSHSPEVTEQKLRACLEDSVNEHSAHCPHTPEFSVTEGTEEKSCLLMSCLVSLPREPVVERGQQLVLFPPW", "length": 231, "header": "tr|A0ABI0P042-1|A0ABI0P042_BOVIN Isoform 1 of RPA interacting protein OS=Bos taurus OX=9913 GN=RPAIN PE=4 SV=1 CANONICAL=A0ABI0P042-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SEC6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042/entry#A0AAA9SEC6-1", "sequence": { "sequence": "MAERPGSRHHSLYKLTGSPPWKEAFRQGCLERMRNSRDRLLSKYRQAGGSMSGGAQNTLLVQEVMEEEWNALQSVESWPQAWAQLEEPMDLAVLEEIQQELIDQEQSIISEYEKSLQFDEQCLSVMLAEWEANPLICPVCTKLVILGL", "length": 148, "header": "tr|A0AAA9SEC6-1|A0ABI0P042_BOVIN Computationally mapped isoform of RPA interacting protein OS=Bos taurus OX=9913 GN=RPAIN PE=4 SV=1 CANONICAL=A0ABI0P042-1" }, "locus": { "chromosome": "19", "start_pos": 26127121, "end_pos": 26120571, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122663.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122663.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081936.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081936.1" } ] } }, { "isoform_ac": "A0AAA9T3R2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042/entry#A0AAA9T3R2-1", "sequence": { "sequence": "MAERPGSRHHSLYKLTGSPPWKEAFRQGCLERMRNSRDRLLSKYRQAGGSMSGGAQNTLLVQEVMEEEWNALQSVESWPQAWAQLEEPMDLAVLEEIQQELIDQGL", "length": 106, "header": "tr|A0AAA9T3R2-1|A0ABI0P042_BOVIN Computationally mapped isoform of RPA interacting protein OS=Bos taurus OX=9913 GN=RPAIN PE=4 SV=1 CANONICAL=A0ABI0P042-1" }, "locus": { "chromosome": "19", "start_pos": 26127121, "end_pos": 26120585, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110102.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110102.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091129.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091129.1" } ] } }, { "isoform_ac": "A0AAA9T6J4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042/entry#A0AAA9T6J4-1", "sequence": { "sequence": "MAERPGSRHHSLYKLTGSPPWKEAFRQGCLERMRNSRDRLLSKYRQAGGSMSGGAQNTLLVQEVMEEEWNALQSVESWPQAWAQLEEPMDLAVLEEIQQELIDQEQSIISEYEKSLQFDEQCLSVMLAEWEANPLICPVCTKYNLRIAGGLVVCQCGLYIQSHACDTWAVIL", "length": 172, "header": "tr|A0AAA9T6J4-1|A0ABI0P042_BOVIN Computationally mapped isoform of RPA interacting protein OS=Bos taurus OX=9913 GN=RPAIN PE=4 SV=2 CANONICAL=A0ABI0P042-1" }, "locus": { "chromosome": "19", "start_pos": 26127121, "end_pos": 26120563, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113782.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113782.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092202.2", "url": "https://www.ensembl.org/id/ENSBTAP00000092202.2" } ] } }, { "isoform_ac": "A0AAA9TAV0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042/entry#A0AAA9TAV0-1", "sequence": { "sequence": "MAERPGSRHHSLYKLTGSPPWKEAFRQGCLERMRNSRDRLLSKYRQAGGSMSGGAQNTLLVQEVMEEEWNALQSVESWPQAWAQLEEPMDLAVLEEIQQELIDQVSG", "length": 107, "header": "tr|A0AAA9TAV0-1|A0ABI0P042_BOVIN Computationally mapped isoform of RPA interacting protein OS=Bos taurus OX=9913 GN=RPAIN PE=4 SV=1 CANONICAL=A0ABI0P042-1" }, "locus": { "chromosome": "19", "start_pos": 26127121, "end_pos": 26120985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122151.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122151.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093137.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093137.1" } ] } }, { "isoform_ac": "A0ABI0P042-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042/entry#A0ABI0P042-1", "sequence": { "sequence": "MAERPGSRHHSLYKLTGSPPWKEAFRQGCLERMRNSRDRLLSKYRQAGGSMSGGAQNTLLVQEVMEEEWNALQSVESWPQAWAQLEEPMDLAVLEEIQQELIDQEQSIISEYEKSLQFDEQCLSVMLAEWEANPLICPVCTKYNLRIAGGLVVCQCGLYIQSHSPEVTEQKLRACLEDSVNEHSAHCPHTPEFSVTEGTEEKSCLLMSCLVSLPREPVVERGQQLVLFPPW", "length": 231, "header": "tr|A0ABI0P042-1|A0ABI0P042_BOVIN Isoform 1 of RPA interacting protein OS=Bos taurus OX=9913 GN=RPAIN PE=4 SV=1 CANONICAL=A0ABI0P042-1" }, "locus": { "chromosome": "19", "start_pos": 26127121, "end_pos": 26120788, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150364.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150364.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107455.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107455.1" } ] } }, { "isoform_ac": "F6QAL6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042/entry#F6QAL6-1", "sequence": { "sequence": "MAERPGSRHHSLYKLTGSPPWKEAFRQGCLERMRNSRDRLLSKYRQAGGSMSGGAQNTLLVQEVMEEEWNALQSVESWPQAWAQLEEPMDLAVLEEIQQELIDQEQSIISEYEKSLQFDEQCLSVMLAEWEANPLICPVCTKYNLRIAGGLVVCQCGLYIQSHFNLSVFQSPEVTEQKLRACLEDSVNEHSAHCPHTPEFSVTEGTEEKSCLLMSCLACDTWAVIL", "length": 226, "header": "tr|F6QAL6-1|A0ABI0P042_BOVIN Computationally mapped isoform of RPA interacting protein OS=Bos taurus OX=9913 GN=RPAIN PE=4 SV=1 CANONICAL=A0ABI0P042-1" }, "locus": { "chromosome": "19", "start_pos": 26127121, "end_pos": 26120563, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000035212.5", "url": "https://www.ensembl.org/id/ENSBTAT00000035212.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000035090.4", "url": "https://www.ensembl.org/id/ENSBTAP00000035090.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P042", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P042", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042" }, { "id": "PF14768", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14768" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RPA-interacting protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 211, "start_aa": "Ile", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042" }, { "id": "PF14766", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14766" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RPA-interacting protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 47, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P042" }, { "id": "PF14767", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14767" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RPA-interacting protein central", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 126, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NVV6-1", "uniprot_ac": "A0ABI0NVV6", "uniprot_id": "A0ABI0NVV6_BOVIN", "mass": { "chemical_mass": 55105.0, "monoisotopic_mass": 55105.0 }, "refseq": {}, "gene_names": [ { "name": "GPATCH2L", "type": "recommended", "evidence": [ { "id": "A0ABI0NVV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVV6" } ] } ], "protein_names": [ { "name": "G-patch domain containing 2 like", "type": "synonym", "evidence": [ { "id": "A0ABI0NVV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVV6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVV6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVV6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPATCH2L", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVV6", "locus": {} } ], "crossref": [ { "id": "509393", "url": "https://www.ncbi.nlm.nih.gov/gene/509393", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051189", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051189", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14195", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14195", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0AAA9SMQ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T432", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T432", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T432-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T432-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTF7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTF7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVV6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVV6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYJ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZY5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZY5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDELVHDLASALEQTSEQNKLGELWEEMALSPRQQRRQLRKRRGRKRRSDFTHLAEHTCCYSEASESSLDEALKDCREMAPVTNFSDSDDTMVVKRHPALNAIVKSKQHSWHESDSFTENAPCRPLRRRRKVKRVTSEVAASLQQKLKVSDWSYERGCRFKSAKKQRLSRWKENTPWTSSGHGLCESAENRTFLSKTGRKERMECEADEQKQGSDENMSECETSSVCSSSDTGLFTNDEGRQGDDEQSDWFYEGECVPGFTVPNLLPKWAPDHCSEVERMDSGLDKLSDSTFLLPSRPAQRGYHARFNRLPGAAARCLRKGRRRLVGKESSISNLGTERIGHLISDPRQKDFWLPSAGKRERNQLFTGNICQDKDKFNPLSPLYSLDVLADASHRRCSPAHCSARQANIHLGPPCSRDIKRKRKPVATVSLSSPNAVHMDAVESATAASQAPRPPDSEWLVRTSAAEKATDSAAATSFKMPQEKSPGYS", "length": 489, "header": "tr|A0ABI0NVV6-1|A0ABI0NVV6_BOVIN Isoform 1 of G-patch domain containing 2 like OS=Bos taurus OX=9913 GN=GPATCH2L PE=4 SV=1 CANONICAL=A0ABI0NVV6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SMQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVV6/entry#A0AAA9SMQ5-1", "sequence": { "sequence": "MDELVHDLASALEQTSEQNKLGELWEEMALSPRQQRRQLRKRRGRKRRSDFTHLAEHTCCYSEASESSLDEALKDCREMAPVTNFSDSDDTMVVKRHPALNAIVKSKQHSWHESDSFTENAPCRPLRRRRKVKRVTSEVAASLQQKLKVSDWSYERGCRFKSAKKQRLSRWKENTPWTSSGHGLCESAENRTFLSKTGRKERMECEADEQKQGSDENMSECETSSVCSSSDTGLFTNDEGRQGDDEQSDWFYEGECVPGFTVPNLLPKWAPDHCSEVERMDSGLDKLSDSTFLLPSRPAQRGYHARFNRLPGAAARCLRKGRRRLVGKESSISNLGTERIGHLISDPRQKDFWLPSAGKRERNQLFTGNICQDKDKFNPLSPLYSLDVLADASHRRCSPAHCSARQANIHLGPPCSRDIKRKRKPVATVSLSSPNAVPHGGEGHSPSPRHQSVEQMGLLCLTSGHLGFHLFYRNE", "length": 475, "header": "tr|A0AAA9SMQ5-1|A0ABI0NVV6_BOVIN Computationally mapped isoform of G-patch domain containing 2 like OS=Bos taurus OX=9913 GN=GPATCH2L PE=4 SV=2 CANONICAL=A0ABI0NVV6-1" }, "locus": { "chromosome": "10", "start_pos": 87509669, "end_pos": 87461670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119528.2", "url": "https://www.ensembl.org/id/ENSBTAT00000119528.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084045.2", "url": "https://www.ensembl.org/id/ENSBTAP00000084045.2" } ] } }, { "isoform_ac": "A0AAA9T432-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVV6/entry#A0AAA9T432-1", "sequence": { "sequence": "MFLLMLLTEGVHQRTALPDRQTYTWGPHVHVTSRGNGNLWPQCRCPAQMPVIRYSYPSLTTCCVSGTKLYVLYTFSCHLYEKVGHFIPIFYGKTENVKSNL", "length": 101, "header": "tr|A0AAA9T432-1|A0ABI0NVV6_BOVIN Computationally mapped isoform of G-patch domain containing 2 like OS=Bos taurus OX=9913 GN=GPATCH2L PE=4 SV=1 CANONICAL=A0ABI0NVV6-1" }, "locus": { "chromosome": "10", "start_pos": 87507869, "end_pos": 87490901, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123856.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123856.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091263.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091263.1" } ] } }, { "isoform_ac": "A0ABI0NTF7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVV6/entry#A0ABI0NTF7-1", "sequence": { "sequence": "MDELVHDLASALEQTSEQNKLGELWEEMALSPRQQRRQLRKRRGRKRRSDFTHLAEHTCCYSEASESSLDEALKDCREMAPVTNFSDSDDTMVVKRHPALNAIVKSKQHSWHESDSFTENAPCRPLRRRRKVKRVTSEVAASLQQKLKVSDWSYERGCRFKSAKKQRLSRWKENTPWTSSGHGLCESAENRTFLSKTGRKERMECEADEQKQGSDENMSECETSSVCSSSDTGLFTNDEGRQGDDEQSDWFYEGECVPGFTVPNLLPKWAPDHCSEVERMDSGLDKLSDSTFLLPSRPAQRGYHARFNRLPGAAARCLRKGRRRLVGKESSISNLGTERIGHLISDPRQKEKNKALASGFPHISACAHEFNPLSPLYSLDVLADASHRRCSPAHCSARQANIHLGPPCSRDIKRKRKPVATVSLSSPNAVHMDAVESATAASQAPRPPDSEWLVRTSAAEKATDSAAATSFKMPQEKSPGYS", "length": 482, "header": "tr|A0ABI0NTF7-1|A0ABI0NVV6_BOVIN Computationally mapped isoform of G-patch domain containing 2 like OS=Bos taurus OX=9913 GN=GPATCH2L PE=4 SV=1 CANONICAL=A0ABI0NVV6-1" }, "locus": { "chromosome": "10", "start_pos": 87514114, "end_pos": 87461670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151727.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151727.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107761.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107761.1" } ] } }, { "isoform_ac": "A0ABI0NVV6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVV6/entry#A0ABI0NVV6-1", "sequence": { "sequence": "MDELVHDLASALEQTSEQNKLGELWEEMALSPRQQRRQLRKRRGRKRRSDFTHLAEHTCCYSEASESSLDEALKDCREMAPVTNFSDSDDTMVVKRHPALNAIVKSKQHSWHESDSFTENAPCRPLRRRRKVKRVTSEVAASLQQKLKVSDWSYERGCRFKSAKKQRLSRWKENTPWTSSGHGLCESAENRTFLSKTGRKERMECEADEQKQGSDENMSECETSSVCSSSDTGLFTNDEGRQGDDEQSDWFYEGECVPGFTVPNLLPKWAPDHCSEVERMDSGLDKLSDSTFLLPSRPAQRGYHARFNRLPGAAARCLRKGRRRLVGKESSISNLGTERIGHLISDPRQKDFWLPSAGKRERNQLFTGNICQDKDKFNPLSPLYSLDVLADASHRRCSPAHCSARQANIHLGPPCSRDIKRKRKPVATVSLSSPNAVHMDAVESATAASQAPRPPDSEWLVRTSAAEKATDSAAATSFKMPQEKSPGYS", "length": 489, "header": "tr|A0ABI0NVV6-1|A0ABI0NVV6_BOVIN Isoform 1 of G-patch domain containing 2 like OS=Bos taurus OX=9913 GN=GPATCH2L PE=4 SV=1 CANONICAL=A0ABI0NVV6-1" }, "locus": { "chromosome": "10", "start_pos": 87514114, "end_pos": 87461670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139388.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139388.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105677.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105677.1" } ] } }, { "isoform_ac": "A0ABI0NYJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVV6/entry#A0ABI0NYJ4-1", "sequence": { "sequence": "MDELVHDLASALEQTSEQNKLGELWEEMALSPRQQRRQLRKRRGRKRRSDFTHLAEHTCCYSEASESSLDEALKDCREMAPVTNFSDSDDTMVVKRHPALNAIVKSKQHSWHESDSFTENAPCRPLRRRRKVKRVTSEVAASLQQKLKVSDWSYERGCRFKSAKKQRLSRWKENTPWTSSGHGLCESAENRTFLSKTGRKERMECEADEQKQGSDENMSECETSSVCSSSDTGLFTNDEGRQGDDEQSDWFYEGECVPGFTVPNLLPKWAPDHCSEVERMDSGLDKLSDSTFLLPSRPAQRGYHARFNRLPGAAARCLRKGRRRLVGKESSISNLGTERIGHLISDPRQKDLILSLPFTPWMFLLMLLTEGVHQRTALPDRQTYTWGPHVHVTSRGNGNLWPQCRCPAQMPFTWMQWSQLQQRHRPPDLQTRSGWSGPLRQRKPLTQLQLRLLKCHRKRALDTARTQYFTHQELTGCC", "length": 478, "header": "tr|A0ABI0NYJ4-1|A0ABI0NYJ4_BOVIN Computationally mapped isoform of G-patch domain containing 2 like OS=Bos taurus OX=9913 GN=GPATCH2L PE=4 SV=1 CANONICAL=A0ABI0NVV6-1" }, "locus": { "chromosome": "10", "start_pos": 87514157, "end_pos": 87461670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138814.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138814.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106469.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106469.1" } ] } }, { "isoform_ac": "A0ABI0NZY5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVV6/entry#A0ABI0NZY5-1", "sequence": { "sequence": "MDELVHDLASALEQTSEQNKLGELWEEMALSPRQQRRQLRKRRGRKRRSDFTHLAEHTCCYSEASESSLDEALKDCREMAPVTNFSDSDDTMVVKRHPALNAIVKSKQHSWHESDSFTENAPCRPLRRRRKVKRVTSEVAASLQQKLKVSDWSYERGCRFKSAKKQRLSRWKENTPWTSSGHGLCESAENRTFLSKTGRKERMECEADEQKQGSDENMSECETSSVCSSSDTGLFTNDEGRQGDDEQSDWFYEGECVPGFTVPNLLPKWAPDHCSEVERMDSGLDKLSDSTFLLPSRPAQRGYHARFNRLPGAAARCLRKGRRRLVGKESSISNLGTERIGHLISDPRQKDFWLPSAGKRERNQVFTSALLCQFTWMQWSQLQQRHRPPDLQTRSGWSGPLRQRKPLTQLQLRLLKCHRKRALDTARTQYFTHQELTGCC", "length": 440, "header": "tr|A0ABI0NZY5-1|A0ABI0NZY5_BOVIN Computationally mapped isoform of G-patch domain containing 2 like OS=Bos taurus OX=9913 GN=GPATCH2L PE=4 SV=1 CANONICAL=A0ABI0NVV6-1" }, "locus": { "chromosome": "10", "start_pos": 87514157, "end_pos": 87461670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138090.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138090.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104000.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104000.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 217, "end_pos": 219 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NVM9-1", "uniprot_ac": "A0ABI0NVM9", "uniprot_id": "A0ABI0NVM9_BOVIN", "mass": { "chemical_mass": 151953.0, "monoisotopic_mass": 151953.0 }, "refseq": {}, "gene_names": [ { "name": "CARMIL2", "type": "recommended", "evidence": [ { "id": "A0ABI0NVM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9" } ] } ], "protein_names": [ { "name": "Capping protein regulator and myosin 1 linker 2", "type": "synonym", "evidence": [ { "id": "A0ABI0NVM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVM9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CARMIL2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9", "locus": { "chromosome": "18", "start_pos": 35208873, "end_pos": 35195766, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018900", "url": "https://www.ensembl.org/id/ENSBTAG00000018900" } ] } } ], "crossref": [ { "id": "ENSBTAG00000018900", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018900", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "510354", "url": "https://www.ncbi.nlm.nih.gov/gene/510354", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:510354", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510354", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24112:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24112:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16000", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16000", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17888", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17888", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SQ95", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQ95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQ95-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQ95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVM9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVM9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MTM9", "url": "https://www.uniprot.org/uniprotkb/F1MTM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MTM9-1", "url": "https://www.uniprot.org/uniprotkb/F1MTM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQTPDGISCELRGEITKFLWPKEAELLLKTWLPEREGAEQGHVLALLRWRAYLLHTCLPLRVDCTFSYLEVQAMVLQETPPQVTFELESLPELVLEFTGVAALEQLAQHIAAAIRKVFPRSTLGKLFRRPTPPSMLARLEKSSSSEATSPSSPCGGFSETYEALCDYNGFPFREEIQWDVDTIYHRQGCRHFSLGDFSHLGSRDLALSVAALSYNLWFRCLSCVDMKLVSLEVSEQILHMMNQSSHLEELVLETCGLRGDFVRRLAQALAGHTSSGLRELSLAGNLLDDRGVAALSRHLEKHPGALRRLSLAQTGLTPRGMRALGRALASNSAFDSALTHLDLSGNPGALGASEDRGGLYSFLSRPNVLTFLNLAGTDTALDTLFAALSRGGCSSLAHLDASRNVFSRTKSRAVPDALQLFLSRAGTLRHLGLAGCKLPPDALRALLEGLALNTHLNDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNGFGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAESRLKLGAGVLLRALGTNPNLTALDISGNAMGDTGAKMLAKALRVNTRLRSVVWDRNHTSALGLLDVAQALEQNHSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNNRTDHTSTDCTSCPKPLGLGSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVHQAEDAIQNANFSLSILPILYEAGSSPSHQWQLRQKLEGLLGQVGEVCRRDIQDFTQATLDTTRSLCPQTLQGPRWREQLEGVLGGSRGLPELLPEHLLQDAFTRLRNMRLSVTGTLAESIVAQAVAGLSAARDRLVESLAQQATEAMPPVIPALDGDESSPLGPGELEGLFFPEEKEKDDEEEQKDESPPQKWPESLHCLHLDSSTHSAAEELEPEPELAAPGEDAEPQAGPSARGSPSPAAPGPPAGPLPRMDLPPSGQPLRHPTRTRPRPRRQHHHRPPPGGPQVPPALPQEGNGLSARVDEGVEEFFSKRLIHQDRLWAPEEDPAAEGGTTPVPRTLRKKLGTLFAFKKPRSTRGSRPDLETSPGAAPRSRKTTLGDLLRPPARPGRGEEPAAGAEGGTSSPDPTRRSRPRYTRESKAYSLILLPAEEEETVGARPDKRRPLERGDTELAPSFEQRVQVMLQRIGVSRGSGSAEGKRKQSKDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGPGGQGPESATWKTLGQQLNAELRGRGWGQQDGPGPPSPCPSPSPRRSSPSPDSLGLPEDPCLGSRNEDGWLRPQPRLAGRRAVSVHEDQLQAPAVCLYPTDRPLRLQRSPVLKRRPKLEAPPSPSIGSGLEAEPLPTQSTEPSSPPSPTTNQRGGGPNP", "length": 1406, "header": "tr|A0ABI0NVM9-1|A0ABI0NVM9_BOVIN Isoform 1 of Capping protein regulator and myosin 1 linker 2 OS=Bos taurus OX=9913 GN=CARMIL2 PE=3 SV=1 CANONICAL=A0ABI0NVM9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SQ95-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9/entry#A0AAA9SQ95-1", "sequence": { "sequence": "MVLQETPPQVTFELESLPELVLEFTGVAALEQLAQHIAAAIRKVFPRSTLGKLFRRPTPPSMLARLEKSSSSEATSPSSPCGGFSETYEALCDYNGFPFREEIQWDVDTIYHRQGCRHFSLGDFSHLGSRDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMNQSSHLEELVLETCGLRGDFVRRLAQALAGHTSSGLRELSLAGNLLDDRGVAALSRHLEKHPGALRRLSLAQTGLTPRGMRALGRALASNSAFDSALTHLDLSGNPGALGASEDRGGLYSFLSRPNVLTFLNLAGTDTALDTLFAALSRGGCSSLAHLDASRNVFSRTKSRAVPDALQLFLSRAGTLRHLGLAGCKLPPDALRALLEGLALNTHLNDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNGFGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAESRLKLGAGVLLRALGTNPNLTALDISGNAMGDTGAKMLAKALRVNTRLRSVVWDRNHTSALGLLDVAQALEQNHSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNNRTDHTSTDCTSCPKPLGLGSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVHQAEDAIQNANFSLSILPILYEAGSSPSHQWQLRQKLEGLLGQVGEVCRRDIQDFTQATLDTTRSLCPQTLQGPRWREQLEGVLGGSRGLPELLPEHLLQDAFTRLRNMRLSVTGTLAESIVAQAVAGLSAARDRLVESLAQQATEAMPPVIPALDGDESSPLGPGELEGLFFPEEKEKDDEEEQKDESPPQKWPESLHCLHLDSSTHSAAEELEPEPELAAPGEDAEPQAGPSARGSPSPAAPGPPAGPLPRMDLPPSGQPLRHPTRTRPRPRRQHHHRPPPGGPQVPPALPQEGNGLSARVDEGVEEFFSKRLIHQDRLWAPEEDPAAEGGTTPVPRTLRKKLGTLFAFKKPRSTRGSRPDLETSPGAAPRSRKTTLGDLLRPPARPGRGEEPAAGAEGGTSSPDPTRRSRPRYTRESKAYSLILLPAEEEETVGARPDKRRPLERGDTELAPSFEQRVQVMLQRIGVSRGSGSAEGKRKQSKDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGPGGQGPESATWKTLGQQLNAELRGRGWGQQDGPGPPSPCPSPSPRRSSPSPDSLGLPEDPCLGSRNEDGWLRPQPRLAGRRAVSVHEDQLQAPADRPLRLQRSPVLKRRPKLEAPPSPSIGKGGQGQLGGRQGCLVQS", "length": 1310, "header": "tr|A0AAA9SQ95-1|A0ABI0NVM9_BOVIN Computationally mapped isoform of Capping protein regulator and myosin 1 linker 2 OS=Bos taurus OX=9913 GN=CARMIL2 PE=3 SV=2 CANONICAL=A0ABI0NVM9-1" }, "locus": { "chromosome": "18", "start_pos": 35207828, "end_pos": 35196872, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091230.2", "url": "https://www.ensembl.org/id/ENSBTAT00000091230.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086166.2", "url": "https://www.ensembl.org/id/ENSBTAP00000086166.2" } ] } }, { "isoform_ac": "A0ABI0NVM9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9/entry#A0ABI0NVM9-1", "sequence": { "sequence": "MAQTPDGISCELRGEITKFLWPKEAELLLKTWLPEREGAEQGHVLALLRWRAYLLHTCLPLRVDCTFSYLEVQAMVLQETPPQVTFELESLPELVLEFTGVAALEQLAQHIAAAIRKVFPRSTLGKLFRRPTPPSMLARLEKSSSSEATSPSSPCGGFSETYEALCDYNGFPFREEIQWDVDTIYHRQGCRHFSLGDFSHLGSRDLALSVAALSYNLWFRCLSCVDMKLVSLEVSEQILHMMNQSSHLEELVLETCGLRGDFVRRLAQALAGHTSSGLRELSLAGNLLDDRGVAALSRHLEKHPGALRRLSLAQTGLTPRGMRALGRALASNSAFDSALTHLDLSGNPGALGASEDRGGLYSFLSRPNVLTFLNLAGTDTALDTLFAALSRGGCSSLAHLDASRNVFSRTKSRAVPDALQLFLSRAGTLRHLGLAGCKLPPDALRALLEGLALNTHLNDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNGFGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAESRLKLGAGVLLRALGTNPNLTALDISGNAMGDTGAKMLAKALRVNTRLRSVVWDRNHTSALGLLDVAQALEQNHSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNNRTDHTSTDCTSCPKPLGLGSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVHQAEDAIQNANFSLSILPILYEAGSSPSHQWQLRQKLEGLLGQVGEVCRRDIQDFTQATLDTTRSLCPQTLQGPRWREQLEGVLGGSRGLPELLPEHLLQDAFTRLRNMRLSVTGTLAESIVAQAVAGLSAARDRLVESLAQQATEAMPPVIPALDGDESSPLGPGELEGLFFPEEKEKDDEEEQKDESPPQKWPESLHCLHLDSSTHSAAEELEPEPELAAPGEDAEPQAGPSARGSPSPAAPGPPAGPLPRMDLPPSGQPLRHPTRTRPRPRRQHHHRPPPGGPQVPPALPQEGNGLSARVDEGVEEFFSKRLIHQDRLWAPEEDPAAEGGTTPVPRTLRKKLGTLFAFKKPRSTRGSRPDLETSPGAAPRSRKTTLGDLLRPPARPGRGEEPAAGAEGGTSSPDPTRRSRPRYTRESKAYSLILLPAEEEETVGARPDKRRPLERGDTELAPSFEQRVQVMLQRIGVSRGSGSAEGKRKQSKDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGPGGQGPESATWKTLGQQLNAELRGRGWGQQDGPGPPSPCPSPSPRRSSPSPDSLGLPEDPCLGSRNEDGWLRPQPRLAGRRAVSVHEDQLQAPAVCLYPTDRPLRLQRSPVLKRRPKLEAPPSPSIGSGLEAEPLPTQSTEPSSPPSPTTNQRGGGPNP", "length": 1406, "header": "tr|A0ABI0NVM9-1|A0ABI0NVM9_BOVIN Isoform 1 of Capping protein regulator and myosin 1 linker 2 OS=Bos taurus OX=9913 GN=CARMIL2 PE=3 SV=1 CANONICAL=A0ABI0NVM9-1" }, "locus": { "chromosome": "18", "start_pos": 35207959, "end_pos": 35196028, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144312.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144312.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104796.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104796.1" } ] } }, { "isoform_ac": "F1MTM9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9/entry#F1MTM9-1", "sequence": { "sequence": "MAQTPDGISCELRGEITKFLWPKEAELLLKTWLPEREGAEQGHVLALLRWRAYLLHTCLPLRVDCTFSYLEVQAMVLQETPPQVTFELESLPELVLEFTGVAALEQLAQHIAAAIRKVFPRSTLGKLFRRPTPPSMLARLEKSSSSEATSPSSPCGGFSETYEALCDYNGFPFREEIQWDVDTIYHRQGCRHFSLGDFSHLGSRDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMNQSSHLEELVLETCGLRGDFVRRLAQALAGHTSSGLRELSLAGNLLDDRGVAALSRHLEKHPGALRRLSLAQTGLTPRGMRALGRALASNSAFDSALTHLDLSGNPGALGASEDRGGLYSFLSRPNVLTFLNLAGTDTALDTLFAALSRGGCSSLAHLDASRNVFSRTKSRAVPDALQLFLSRAGTLRHLGLAGCKLPPDALRALLEGLALNTHLNDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNGFGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAESRLKLGAGVLLRALGTNPNLTALDISGNAMGDTGAKMLAKALRVNTRLRSVVWDRNHTSALGLLDVAQALEQNHSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNNRTDHTSTDCTSCPKPLGLGSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVHQAEDAIQNANFSLSILPILYEAGSSPSHQWQLRQKLEGLLGQVGEVCRRDIQDFTQATLDTTRSLCPQTLQGPRWREQLEGVLGGSRGLPELLPEHLLQDAFTRLRNMRLSVTGTLAESIVAQAVAGLSAARDRLVESLAQQATEAMPPVIPALDGDESSPLGPGELEGLFFPEEKEKDDEEEQKDESPPQKWPESLHCLHLDSSTHSAAEELEPEPELAAPGEDAEPQAGPSARGSPSPAAPGPPAGPLPRMDLPPSGQPLRHPTRTRPRPRRQHHHRPPPGGPQVPPALPQEGNGLSARVDEGVEEFFSKRLIHQDRLWAPEEDPAAEGGTTPVPRTLRKKLGTLFAFKKPRSTRGSRPDLETSPGAAPRSRKTTLGDLLRPPARPGRGEEPAAGAEGGTSSPDPTRRSRPRYTRESKAYSLILLPAEEEETVGARPDKRRPLERGDTELAPSFEQRVQVMLQRIGVSRGSGSAEGKRKQSKDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGPGGQGPESATWKTLGQQLNAELRGRGWGQQDGPGPPSPCPSPSPRRSSPSPDSLGLPEDPCLGSRNEDRPLRLQRSPVLKRRPKLEAPPSPSIGSGLEAEPLPTQSTEPSSPPSPTTNQRGGGPNP", "length": 1372, "header": "tr|F1MTM9-1|A0ABI0NVM9_BOVIN Computationally mapped isoform of Capping protein regulator and myosin 1 linker 2 OS=Bos taurus OX=9913 GN=CARMIL2 PE=3 SV=4 CANONICAL=A0ABI0NVM9-1" }, "locus": { "chromosome": "18", "start_pos": 35207959, "end_pos": 35196028, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025153.8", "url": "https://www.ensembl.org/id/ENSBTAT00000025153.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025153.7", "url": "https://www.ensembl.org/id/ENSBTAP00000025153.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:510354", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510354", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVM9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVM9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVM9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVM9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9" } ], "pmid": "" }, { "name": "regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:0034315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034315", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVM9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 612, "end_pos": 614, "annotation": "n_glycosylation_sequon" }, { "start_pos": 629, "end_pos": 631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" }, { "start_pos": 732, "end_pos": 734, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NVM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9" }, { "id": "PF16000", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16000" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CARMIL C-terminal", "eco_id": "ECO_0000259", "start_pos": 784, "end_pos": 1079, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NVM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVM9" }, { "id": "PF17888", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CARMIL pleckstrin homology", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 120, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NXN4-1", "uniprot_ac": "A0ABI0NXN4", "uniprot_id": "A0ABI0NXN4_BOVIN", "mass": { "chemical_mass": 24671.0, "monoisotopic_mass": 24671.0 }, "refseq": {}, "gene_names": [ { "name": "CATSPERZ", "type": "recommended", "evidence": [ { "id": "A0ABI0NXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN4" } ] } ], "protein_names": [ { "name": "Catsper channel auxiliary subunit zeta", "type": "synonym", "evidence": [ { "id": "A0ABI0NXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXN4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CATSPERZ", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN4", "locus": { "chromosome": "29", "start_pos": 42602893, "end_pos": 42599760, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000060362", "url": "https://www.ensembl.org/id/ENSBTAG00000060362" } ] } } ], "crossref": [ { "id": "107131976", "url": "https://www.ncbi.nlm.nih.gov/gene/107131976", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039019", "url": 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"categories": [ "Protein" ] }, { "id": "A0ABI0NXN4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGKPLKVRTLPGPPHPASSQAHPGPLTVLSFSPGSGQLPTITPHAPHLPPPPAGECQPWLGSGSLVPACSPSPPDSPRPSASLVVCGPQASAKSSSHHGSGRSSLQDIRNMWTTATLSQPKLNVQLPTVREDSELEDVSVSEKPSSVSSLNISRHTPHRAYWVEQQSRLPLPLTELMENEALEILTEALRSYQSEIGRDHSLTKQLQRYIEGLKRRRNRRLQVLAV", "length": 227, "header": "tr|A0ABI0NXN4-1|A0ABI0NXN4_BOVIN Isoform 1 of Catsper channel auxiliary subunit zeta OS=Bos taurus OX=9913 GN=CATSPERZ PE=4 SV=1 CANONICAL=A0ABI0NXN4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SQZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN4/entry#A0AAA9SQZ8-1", "sequence": { "sequence": "MEGKPLKASAKSSSHHGSGRSSLQDIRNMWTTATLSQPKLNVQLPTVREDSELEDVSVSGKTLWSYDQKAGHDAEGGWEASDGGEDKDSFKPEEPEELELGGDSSQGSRLEEDDSKTDNEKPSSVSSLNISRHTPHRAYWVEQQSRLPLPLTELMENEALEILTEALRSYQSEIGRDHSLTKQLQRYIEGLKRRRNRRLQVLAV", "length": 204, "header": "tr|A0AAA9SQZ8-1|A0ABI0NXN4_BOVIN Computationally mapped isoform of Catsper channel auxiliary subunit zeta OS=Bos taurus OX=9913 GN=CATSPERZ PE=4 SV=1 CANONICAL=A0ABI0NXN4-1" }, "locus": { "chromosome": "29", "start_pos": 42602763, "end_pos": 42599959, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127956.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127956.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087772.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087772.1" } ] } }, { "isoform_ac": "A0ABI0NXN4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN4/entry#A0ABI0NXN4-1", "sequence": { "sequence": "MEGKPLKVRTLPGPPHPASSQAHPGPLTVLSFSPGSGQLPTITPHAPHLPPPPAGECQPWLGSGSLVPACSPSPPDSPRPSASLVVCGPQASAKSSSHHGSGRSSLQDIRNMWTTATLSQPKLNVQLPTVREDSELEDVSVSEKPSSVSSLNISRHTPHRAYWVEQQSRLPLPLTELMENEALEILTEALRSYQSEIGRDHSLTKQLQRYIEGLKRRRNRRLQVLAV", "length": 227, "header": "tr|A0ABI0NXN4-1|A0ABI0NXN4_BOVIN Isoform 1 of Catsper channel auxiliary subunit zeta OS=Bos taurus OX=9913 GN=CATSPERZ PE=4 SV=1 CANONICAL=A0ABI0NXN4-1" }, "locus": { "chromosome": "29", "start_pos": 42602763, "end_pos": 42599959, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146613.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146613.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105995.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105995.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:107131976", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:107131976", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "CatSper complex", "id": "GO:0036128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036128", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXN4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXN4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN4" } ], "pmid": "" }, { "name": "sperm capacitation", "id": "GO:0048240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048240", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXN4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NZP2-1", "uniprot_ac": "A0ABI0NZP2", "uniprot_id": "A0ABI0NZP2_BOVIN", "mass": { "chemical_mass": 61499.0, "monoisotopic_mass": 61499.0 }, "refseq": { "ac": "XP_002692086", "name": "serine palmitoyltransferase 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692086" }, "gene_names": [ { "name": "SPTLC3", "type": "recommended", "evidence": [ { "id": "A0ABI0NZP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP2" } ] }, { "name": "SPTLC3", "type": "synonym", "evidence": [ { "id": "XP_002692086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692086" } ] } ], "protein_names": [ { "name": "serine C-palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "A0ABI0NZP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP2/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.50", "type": "synonym", "evidence": [ { "id": "A0ABI0NZP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP2/entry#names_and_taxonomy" } ] }, { "name": "serine palmitoyltransferase 3", "type": "synonym", "evidence": [ { "id": "XP_002692086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692086" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZP2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SPTLC3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP2", "locus": {} } ], "crossref": [ { "id": "cd06454", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06454", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100336940", "url": "https://www.ncbi.nlm.nih.gov/gene/100336940", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100336940", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336940", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR13693", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13693", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13693:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13693:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00155", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00155", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002692086", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692086", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SRY6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SRY6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTE8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTE8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZP2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZP2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADPGGGAVYNGTPHNQSAADCHGGNCWKNGVVKESQQNGNSNFYRPIVESFEEAPLHVMVFTYLGYGIGTLFGYLRDFLRNSGIEKCNAAVEREEQKDFVPLYQNFENFYIRNIYMRIRDNWNRPICSAPGAVFDVMERVTDDYNWTFRFTGRIIKDVINMGSYNFLGLAAKYDESMRTVKEVIETYGLGVGSTRQEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNVQSLEKLLRDAVIYGQPRTRRAWRKILILVEGIYSMEGSIVHLPDIVALKKKYKAYLYMDEAHSIGSVGPTGRGVVEFFGLDPRDIDVYMGTFTKSFGAAGGYIAGRKDLVDYLRTHSHSAAYGTSMSPPVAEQIIRVMKLIMGLDGTTEGLQRVQQLAKNTRYFRQRLSKMGFIVYGNEESPVVPLLLYMPAKVAAFARHLLNRKIGVVVVGFPATPLAEARARFCVSAAHTQEMLDTVLEALDEMGDLLNLKYSRNRKSARPELYDEMSFELED", "length": 549, "header": "tr|A0ABI0NZP2-1|A0ABI0NZP2_BOVIN Isoform 1 of serine C-palmitoyltransferase OS=Bos taurus OX=9913 GN=SPTLC3 PE=3 SV=1 CANONICAL=A0ABI0NZP2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SRY6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP2/entry#A0AAA9SRY6-1", "sequence": { "sequence": "MADPGGGAVYNGTPHNQSAADCHGGNCWKNGVVKESQQNGNSNFYRPIVESFEEAPLHVMVFTYLGYGIGTLFGYLRDFLRNSGIEKCNAAVEREEQKDFVPLYQNFENFYIRNIYMRIRDNWNRPICSAPGAVFDVMERVTDDYNWTFRFTGRIIKDVINMGSYNFLGLAAKYDESMRTVKEVIETYGLGVGSTRQEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNVQSLEKLLRDAVIYGQPRTRRAWRKILILVEGIYSMEGSIVHLPDIVALKKKYKAYLYMDEAHSIGSVGPTGRGVVEFFGLDPRDIDVYMGTFTKSFGAAGGYIAGRKDLVDYLRTHSHSAAYGTSMSPPVAEQIIRVMKLIMGLDGTTEGTLRASSLAFTRNTSASFSQNLIPGHGRASCLEGCKPRLSIQTIKLILWPFLLTYSSPRSSMRNKEGQPDRTVIRQ", "length": 499, "header": "tr|A0AAA9SRY6-1|A0ABI0NZP2_BOVIN Computationally mapped isoform of serine C-palmitoyltransferase OS=Bos taurus OX=9913 GN=SPTLC3 PE=3 SV=2 CANONICAL=A0ABI0NZP2-1" }, "locus": { "chromosome": "13", "start_pos": 6724899, "end_pos": 6599781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120278.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120278.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086845.2", "url": "https://www.ensembl.org/id/ENSBTAP00000086845.2" } ] } }, { "isoform_ac": "A0ABI0NTE8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP2/entry#A0ABI0NTE8-1", "sequence": { "sequence": "MPVNLENSAVATELEKQNGNSNFYRPIVESFEEAPLHVMVFTYLGYGIGTLFGYLRDFLRNSGIEKCNAAVEREEQKDFVPLYQNFENFYIRNIYMRIRDNWNRPICSAPGAVFDVMERVTDDYNWTFRFTGRIIKDVINMGSYNFLGLAAKYDESMRTVKEVIETYGLGVGSTRQEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNVQSLEKLLRDAVIYGQPRTRRAWRKILILVEGIYSMEGSIVHLPDIVALKKKYKAYLYMDEAHSIGSVGPTGRGVVEFFGLDPRDIDVYMGTFTKSFGAAGGYIAGRKDLVDYLRTHSHSAAYGTSMSPPVAEQIIRVMKLIMGLDGTTEGLQRVQQLAKNTRYFRQRLSKMGFIVYGNEESPVVPLLLYMPAKVAAFARHLLNRKIGVVVVGFPATPLAEARARFCVSAAHTQEMLDTVLEALDEMGDLLNLKYSRNRKSARPELYDEMSFELED", "length": 528, "header": "tr|A0ABI0NTE8-1|A0ABI0NZP2_BOVIN Computationally mapped isoform of serine C-palmitoyltransferase OS=Bos taurus OX=9913 GN=SPTLC3 PE=3 SV=1 CANONICAL=A0ABI0NZP2-1" }, "locus": { "chromosome": "13", "start_pos": 6747767, "end_pos": 6634224, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146135.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146135.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103997.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103997.1" } ] } }, { "isoform_ac": "A0ABI0NZP2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP2/entry#A0ABI0NZP2-1", "sequence": { "sequence": "MADPGGGAVYNGTPHNQSAADCHGGNCWKNGVVKESQQNGNSNFYRPIVESFEEAPLHVMVFTYLGYGIGTLFGYLRDFLRNSGIEKCNAAVEREEQKDFVPLYQNFENFYIRNIYMRIRDNWNRPICSAPGAVFDVMERVTDDYNWTFRFTGRIIKDVINMGSYNFLGLAAKYDESMRTVKEVIETYGLGVGSTRQEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNVQSLEKLLRDAVIYGQPRTRRAWRKILILVEGIYSMEGSIVHLPDIVALKKKYKAYLYMDEAHSIGSVGPTGRGVVEFFGLDPRDIDVYMGTFTKSFGAAGGYIAGRKDLVDYLRTHSHSAAYGTSMSPPVAEQIIRVMKLIMGLDGTTEGLQRVQQLAKNTRYFRQRLSKMGFIVYGNEESPVVPLLLYMPAKVAAFARHLLNRKIGVVVVGFPATPLAEARARFCVSAAHTQEMLDTVLEALDEMGDLLNLKYSRNRKSARPELYDEMSFELED", "length": 549, "header": "tr|A0ABI0NZP2-1|A0ABI0NZP2_BOVIN Isoform 1 of serine C-palmitoyltransferase OS=Bos taurus OX=9913 GN=SPTLC3 PE=3 SV=1 CANONICAL=A0ABI0NZP2-1" }, "locus": { "chromosome": "13", "start_pos": 6747767, "end_pos": 6599781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141742.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141742.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105744.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105744.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 344, "start_aa": "Thr", "end_pos": 344, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr344", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100336940", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336940", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZP2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP2" } ], "pmid": "" }, { "name": "acyltransferase activity", "id": "GO:0016746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016746", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZP2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NZP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZP2" }, { "id": "PF00155", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00155" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminotransferase class I/classII large", "eco_id": "ECO_0000259", "start_pos": 157, "end_pos": 517, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.50", "ec_name": "L-serine + hexadecanoyl-CoA + H(+) = 3-oxosphinganine + CO2 + CoA.", "evidence": [ { "id": "2.3.1.50", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.50" }, { "id": "2.3.1.50", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.50" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 344 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 16, "end_pos": 18 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NWQ4-1", "uniprot_ac": "A0ABI0NWQ4", "uniprot_id": "A0ABI0NWQ4_BOVIN", "mass": { "chemical_mass": 53050.0, "monoisotopic_mass": 53050.0 }, "refseq": { "ac": "XP_059732981", "name": "zinc finger protein 82 homolog isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059732981" }, "gene_names": [ { "name": "ZNF566", "type": "recommended", "evidence": [ { "id": "A0ABI0NWQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4" } ] }, { "name": "ZNF420", "type": "synonym", "evidence": [ { "id": "XP_059732981", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059732981" } ] }, { "name": "ZNF566", "type": "synonym", "evidence": [ { "id": "XP_059732981", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059732981" } ] } ], "protein_names": [ { "name": "Zinc finger protein 566", "type": "synonym", "evidence": [ { "id": "A0ABI0NWQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 82 homolog isoform X3", "type": "synonym", "evidence": [ { "id": "XP_059732981", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059732981" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9STF4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STF4#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0AAA9SX89", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX89#function" }, { "database": "UniProtKB", "id": "A0AAF6DM80", "url": 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"url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "767945", "url": "https://www.ncbi.nlm.nih.gov/gene/767945", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19818:SF158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19818:SF158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390:SF260", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390:SF260", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059732981", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059732981", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9STF4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9STF4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SX89", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SX89-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TDJ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TDJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DM80", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DM80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DM80-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DM80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSFLPILLDSSASFQKRSPEKNWSFSANIKAMAQESVMFSDVSIDFSQEEWEFLNDDQRDLYRDVMLENYSNLVSMAGHSISKPDVISFLEQGKEPWLVDRELTRDQWPVLESRCETKKLFLKKEIYEIESAQWELMDRLTRHDLQCSSFRDEWECNGQFEKQHGSQEGHFSQLIFTHEGMPTFSQHPSFTLQQIMNNNKEKYCATKEYRKTFRHDSQLTTHQIIHTVEKPYECKECGKAFRHPSRLSHHQKIHSGKKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFARHQRIHTGEKPYECKECGKAFSSGSNFTQHQRIHTGEKPYECKICGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLTSHHRIHTSEKAYEYRECAKTFNYDSQLVQHQNLYW", "length": 452, "header": "tr|A0ABI0NWQ4-1|A0ABI0NWQ4_BOVIN Isoform 1 of Zinc finger protein 566 OS=Bos taurus OX=9913 GN=ZNF566 PE=3 SV=1 CANONICAL=A0ABI0NWQ4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9STF4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4/entry#A0AAA9STF4-1", "sequence": { "sequence": "MAQESVMFSDVSIDFSQEEWEFLNDDQRDLYRDVMLENYSNLVSMGHSISKPDVISFLEQGKEPWLVDRELTRDQWPVLESRCETKKLFLKKEIYEIESAQWELMDRLTRHDLQCSSFRDEWECNGQFEKQHGSQEGHFSQLIFTHEGMPTFSQHPSFTLQQIMNNNKEKYCATKEYRKTFRHDSQLTTHQIIHTVEKPYECKECGKAFRHPSRLSHHQKIHSGKKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFARHQRIHTGEKPYECKECGKAFSSGSNFTQHQRIHTGEKPYECKICGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQRIHTGRHFLLEKNLGLSTLRALTDRTS", "length": 386, "header": "tr|A0AAA9STF4-1|A0ABI0NWQ4_BOVIN Computationally mapped isoform of Zinc finger protein 566 OS=Bos taurus OX=9913 GN=ZNF566 PE=3 SV=1 CANONICAL=A0ABI0NWQ4-1" }, "locus": { "chromosome": "18", "start_pos": 47083969, "end_pos": 47054598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122612.2", "url": "https://www.ensembl.org/id/ENSBTAT00000122612.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088633.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088633.1" } ] } }, { "isoform_ac": "A0AAA9SX89-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4/entry#A0AAA9SX89-1", "sequence": { "sequence": "MAQESVMFSDVSIDFSQEEWEFLNDDQRDLYRDVMLENYSNLVSMAGHSISKPDVISFLEQGKEPWLVDRELTRDQWPVLESRCETKKLFLKKEIYEIESAQWELMDRLTRHDLQCSSFRDEWECNGQFEKQHGSQEGHFSQLIFTHEGMPTFSQHPSFTLQQIMNNNKEKYCATKEYRKTFRHDSQLTTHQIIHTVEKPYECKECGKAFRHPSRLSHHQKIHSGKKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFARHQRIHTGEKPYECKECGKAFSSGSNFTQHQRIHTGEKPYECKICGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQRIHTGPMTEDKTLSYFIFTRHEEVKYFIINFR", "length": 392, "header": "tr|A0AAA9SX89-1|A0ABI0NWQ4_BOVIN Computationally mapped isoform of Zinc finger protein 566 OS=Bos taurus OX=9913 GN=ZNF566 PE=3 SV=1 CANONICAL=A0ABI0NWQ4-1" }, "locus": { "chromosome": "18", "start_pos": 47076900, "end_pos": 47054598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126969.2", "url": "https://www.ensembl.org/id/ENSBTAT00000126969.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091077.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091077.1" } ] } }, { "isoform_ac": "A0AAA9TDJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4/entry#A0AAA9TDJ0-1", "sequence": { "sequence": "MAQESVMFSDVSIDFSQEEWEFLNDDQRDLYRDVMLENYSNLVSMAGHSISKPDVISFLEQGKEPWLVDRELTRDQWPVLESRCETKKLFLKKEIYEIESAQWELMDRLTRHDLQCSSFRDEWECNGQFEKQHGSQEGHFSQLIFTHEGMPTFSQHPSFTLQQIMNNNKEKYCATKEYRKTFRHDSQLTTHQIIHTVEKPYECKECGKAFRHPSRLSHHQKIHSGKKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFARHQRIHTGEKPYECKECGKAFSSGSNFTQHQRIHTGEKPYECKICGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLTSHHRIHTSEKAYEYRECAKTFNYDSQLVQHQNLYW", "length": 420, "header": "tr|A0AAA9TDJ0-1|A0ABI0NWQ4_BOVIN Computationally mapped isoform of Zinc finger protein 566 OS=Bos taurus OX=9913 GN=ZNF566 PE=3 SV=2 CANONICAL=A0ABI0NWQ4-1" }, "locus": { "chromosome": "18", "start_pos": 47072718, "end_pos": 47054598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134030.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134030.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094203.2", "url": "https://www.ensembl.org/id/ENSBTAP00000094203.2" } ] } }, { "isoform_ac": "A0AAF6DM80-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4/entry#A0AAF6DM80-1", "sequence": { "sequence": "MAQESVMFSDVSIDFSQEEWEFLNDDQRDLYRDVMLENYSNLVSMVLESRCETKKLFLKKEIYEIESAQWELMDRLTRHDLQCSSFRDEWECNGQFEKQHGSQEGHFSQLIFTHEGMPTFSQHPSFTLQQIMNNNKEKYCATKEYRKTFRHDSQLTTHQIIHTVEKPYECKECGKAFRHPSRLSHHQKIHSGKKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFARHQRIHTGEKPYECKECGKAFSSGSNFTQHQRIHTGEKPYECKICGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLTSHHRIHTSEKAYEYRECAKTFNYDSQLVQHQNLYW", "length": 387, "header": "tr|A0AAF6DM80-1|A0ABI0NWQ4_BOVIN Computationally mapped isoform of Zinc finger protein 566 OS=Bos taurus OX=9913 GN=ZNF566 PE=3 SV=1 CANONICAL=A0ABI0NWQ4-1" }, "locus": { "chromosome": "18", "start_pos": 47072718, "end_pos": 47054598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006397.8", "url": "https://www.ensembl.org/id/ENSBTAT00000006397.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006397.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006397.6" } ] } }, { "isoform_ac": "A0ABI0NWQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4/entry#A0ABI0NWQ4-1", "sequence": { "sequence": "MRSFLPILLDSSASFQKRSPEKNWSFSANIKAMAQESVMFSDVSIDFSQEEWEFLNDDQRDLYRDVMLENYSNLVSMAGHSISKPDVISFLEQGKEPWLVDRELTRDQWPVLESRCETKKLFLKKEIYEIESAQWELMDRLTRHDLQCSSFRDEWECNGQFEKQHGSQEGHFSQLIFTHEGMPTFSQHPSFTLQQIMNNNKEKYCATKEYRKTFRHDSQLTTHQIIHTVEKPYECKECGKAFRHPSRLSHHQKIHSGKKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFARHQRIHTGEKPYECKECGKAFSSGSNFTQHQRIHTGEKPYECKICGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLTSHHRIHTSEKAYEYRECAKTFNYDSQLVQHQNLYW", "length": 452, "header": "tr|A0ABI0NWQ4-1|A0ABI0NWQ4_BOVIN Isoform 1 of Zinc finger protein 566 OS=Bos taurus OX=9913 GN=ZNF566 PE=3 SV=1 CANONICAL=A0ABI0NWQ4-1" }, "locus": { "chromosome": "18", "start_pos": 47072718, "end_pos": 47052434, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144851.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144851.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104279.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104279.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWQ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NWQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 203, "end_pos": 232, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NWQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWQ4" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 110, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 23, "end_pos": 25 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NXS3-1", "uniprot_ac": "A0ABI0NXS3", "uniprot_id": "A0ABI0NXS3_BOVIN", "mass": { "chemical_mass": 102513.0, "monoisotopic_mass": 102513.0 }, "refseq": {}, "gene_names": [ { "name": "DDX42", "type": "recommended", "evidence": [ { "id": "A0ABI0NXS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3" } ] } ], "protein_names": [ { "name": "ATP-dependent RNA helicase DDX42", "type": "recommended", "evidence": [ { "id": "A0ABI0NXS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "A0ABI0NXS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3/entry#names_and_taxonomy" } ] }, { "name": "DEAD box protein 42", "type": "synonym", "evidence": [ { "id": "A0ABI0NXS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "ATP-dependent RNA helicase that binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Also mediates RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Required for assembly of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs: DDX42 associates transiently with the SF3B subcomplex of the 17S U2 SnRNP complex and is released after fulfilling its role in the assembly of 17S U2 SnRNP. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.", "evidence": [ { "database": "UniProtKB", "id": "E1BJD2", "url": "https://www.uniprot.org/uniprotkb/E1BJD2#function" }, { "database": "UniProtKB", "id": "ARBA00056108", "url": "https://www.uniprot.org/uniprotkb/ARBA00056108#function" }, { "database": "UniProtKB", "id": "A0AAA9STX7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STX7#function" }, { "database": "UniProtKB", "id": "A0ABI0NXS3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3#function" }, { "database": "UniProtKB", "id": "A0ABI0P3K2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K2#function" }, { "database": "UniProtKB", "id": "A0A3Q1LVN5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVN5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXS3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DDX42", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3", "locus": { "chromosome": "19", "start_pos": 48069453, "end_pos": 48051956, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021058", "url": "https://www.ensembl.org/id/ENSBTAG00000021058" } ] } } ], "crossref": [ { "id": "ENSBTAG00000021058", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021058", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17952", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17952", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LVN5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9STX7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9STX7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXS3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXS3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3K2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3K2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJD2", "url": "https://www.uniprot.org/uniprotkb/E1BJD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJD2-1", "url": "https://www.uniprot.org/uniprotkb/E1BJD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGAASSASGFGKSAPPQLPSFYKIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPSKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIATLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENSDRGSNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHSSPDSPIASATKGIPGFGSPGNLSSAPVTYPSAGAPGVNNTASGSNSREGTGGGNGKRERYTENRGGSRHSHGESGNRHGDSPRHGDGGRHGDGGRHGDGYRYPESSSRHTDSRRHADGHPHGENRHGGGGGRHGESRGANDGRNGESRKESCNRESKMDPKVDSPKVDKMDSKTDKTPDGFAVPEPPKRKKSRWDS", "length": 939, "header": "tr|A0ABI0NXS3-1|A0ABI0NXS3_BOVIN Isoform 1 of ATP-dependent RNA helicase DDX42 OS=Bos taurus OX=9913 GN=DDX42 PE=3 SV=1 CANONICAL=A0ABI0NXS3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVN5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3/entry#A0A3Q1LVN5-1", "sequence": { "sequence": "MAAVYLDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPSKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIATLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENSDRGSNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHSSPDSPIASATKGIPGFGSPGNLSSAPVTYPSAGAPGVNNTASGSNSREGTGGGNGKRERYTENRGGSRHSHGESGNRHGDSPRHGDGGRHGDGGRHGDGYRYPESSSRHTDSRRHADGHPHGENRHGGGGGRHGESRGANDGRNGESRKESCNRESKMDPKVDSPKVDKMDSKTDKTPDGFAVPEPPKRKKSRWDS", "length": 821, "header": "tr|A0A3Q1LVN5-1|A0ABI0NXS3_BOVIN Computationally mapped isoform of ATP-dependent RNA helicase DDX42 OS=Bos taurus OX=9913 GN=DDX42 PE=3 SV=3 CANONICAL=A0ABI0NXS3-1" }, "locus": { "chromosome": "19", "start_pos": 48068449, "end_pos": 48050127, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083231.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083231.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061486.3", "url": "https://www.ensembl.org/id/ENSBTAP00000061486.3" } ] } }, { "isoform_ac": "A0AAA9STX7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3/entry#A0AAA9STX7-1", "sequence": { "sequence": "MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGAASSASGFGKSAPPQLPSFYKIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPSKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIATLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENSDRGSNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHSSPDSPIASATKGIPGFGSPGNLSSAPVTYPSAGAPGVNNTASGSNSREGTGGGNGKRERYTENRGGSRHSHGESDGGRHGDGGRHGDGYRYPESSSRHTDSRRHADGHPHGENRHGGGGGRHGESRGANDGRNGESRKESCNRESKMDPKVDSPKVDKMDSKTDKTPDGFAVPEPPKRKKSRWDS", "length": 928, "header": "tr|A0AAA9STX7-1|A0ABI0NXS3_BOVIN Computationally mapped isoform of ATP-dependent RNA helicase DDX42 OS=Bos taurus OX=9913 GN=DDX42 PE=3 SV=2 CANONICAL=A0ABI0NXS3-1" }, "locus": { "chromosome": "19", "start_pos": 48068449, "end_pos": 48043369, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106161.2", "url": "https://www.ensembl.org/id/ENSBTAT00000106161.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088796.2", "url": "https://www.ensembl.org/id/ENSBTAP00000088796.2" } ] } }, { "isoform_ac": "A0ABI0NXS3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3/entry#A0ABI0NXS3-1", "sequence": { "sequence": "MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGAASSASGFGKSAPPQLPSFYKIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPSKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIATLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENSDRGSNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHSSPDSPIASATKGIPGFGSPGNLSSAPVTYPSAGAPGVNNTASGSNSREGTGGGNGKRERYTENRGGSRHSHGESGNRHGDSPRHGDGGRHGDGGRHGDGYRYPESSSRHTDSRRHADGHPHGENRHGGGGGRHGESRGANDGRNGESRKESCNRESKMDPKVDSPKVDKMDSKTDKTPDGFAVPEPPKRKKSRWDS", "length": 939, "header": "tr|A0ABI0NXS3-1|A0ABI0NXS3_BOVIN Isoform 1 of ATP-dependent RNA helicase DDX42 OS=Bos taurus OX=9913 GN=DDX42 PE=3 SV=1 CANONICAL=A0ABI0NXS3-1" }, "locus": { "chromosome": "19", "start_pos": 48068449, "end_pos": 48043369, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141843.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141843.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104913.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104913.1" } ] } }, { "isoform_ac": "A0ABI0P3K2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3/entry#A0ABI0P3K2-1", "sequence": { "sequence": "MAAVYLDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPSKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIATLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENSDRGSNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHSSPDSPIASATKGIPGFGSPGNLSSAPVTYPSAGAPGVNNTASGSNSREGTGGGNGKRERYTENRGGSRHSHGESGNRRSWKQDCSGPKLLLNLK", "length": 719, "header": "tr|A0ABI0P3K2-1|A0ABI0P3K2_BOVIN Computationally mapped isoform of ATP-dependent RNA helicase DDX42 OS=Bos taurus OX=9913 GN=DDX42 PE=3 SV=1 CANONICAL=A0ABI0NXS3-1" }, "locus": { "chromosome": "19", "start_pos": 48069104, "end_pos": 48050127, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142673.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142673.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106058.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106058.1" } ] } }, { "isoform_ac": "E1BJD2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3/entry#E1BJD2-1", "sequence": { "sequence": "MELGMWNICREVCFSACFSRGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPSKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFALLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENSDRGSNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHSSPDSPIASATKGIPGFGSPGNLSSAPVTYPSAGAPGVNNTASGSNSREGTGGGNGKRERYTENRGGSRHSHGESGNRHGDSPRHGDGGRHGDGGRHGDGYRYPESSSRHTDSRRHADGHPHGENRHGGGGGRHGESRGANDGRNGESRKESCNRESKMDPKVDSPKVDKMDSKTDKTPDGFAVPEPPKRKKSRWDS", "length": 806, "header": "tr|E1BJD2-1|A0ABI0NXS3_BOVIN Computationally mapped isoform of ATP-dependent RNA helicase DDX42 OS=Bos taurus OX=9913 GN=DDX42 PE=3 SV=3 CANONICAL=A0ABI0NXS3-1" }, "locus": { "chromosome": "19", "start_pos": 48068449, "end_pos": 48052005, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028046.8", "url": "https://www.ensembl.org/id/ENSBTAT00000028046.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028046.7", "url": "https://www.ensembl.org/id/ENSBTAP00000028046.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXS3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXS3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXS3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXS3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXS3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXS3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXS3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 764, "end_pos": 766, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", "F1N2W9-1", "E1BB03-1", "E1BMP7-1", "A0JND9-1", "E1BAS6-1", "A0AAA9RXM7-1", "Q59HJ6-1", "Q2KJ94-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "A0AAF6Z0E4-1", "G3MZH7-1", "F1MKC7-1", "A0AAA9S7V9-1", "A0AAF6YME1-1", "F1MFR1-1", "Q3T084-1", "E1B7X9-1", "A0ABI0P204-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LG16", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] } ] }, { "uniprot_ac": "A0A3Q1LQC3", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] } ] }, { "uniprot_ac": "A0A3Q1LSH0", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] } ] }, { "uniprot_ac": "A0A3Q1LT80", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] } ] }, { "uniprot_ac": "A0A3Q1LTL4", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] } ] }, { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1LXD0", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] } ] }, { "uniprot_ac": "A0A3Q1M0A4", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A3Q1M0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0A4" } ] } ] }, { "uniprot_ac": "A0A3Q1M155", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] } ] }, { "uniprot_ac": "A0A3Q1M493", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] } ] }, { "uniprot_ac": "A0A3Q1M7R9", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M7R9", "database": 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}, { "uniprot_ac": "A0ABI0P3F2", "gene_name": "DDX3Y", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] } ] }, { "uniprot_ac": "A0ABI0P467", "gene_name": "SKIC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] } ] }, { "uniprot_ac": "A0JND9", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] } ] }, { "uniprot_ac": "A1A4H6", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A1A4H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4H6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A1A4H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4H6" } ] } ] }, { "uniprot_ac": "A4FUD9", "gene_name": "MCM3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A4FUD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FUD9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A4FUD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FUD9" } ] } ] }, { "uniprot_ac": "A4K436", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A4K436", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4K436" } ] } ] }, { "uniprot_ac": "A5D7C1", "gene_name": "DDX52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] } ] }, { "uniprot_ac": "A5PJA1", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] } ] }, { "uniprot_ac": "A5PJI5", "gene_name": "GET3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A5PJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJI5" } ] } ] }, { "uniprot_ac": "A6QLE5", "gene_name": "NLRP3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A6QLE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLE5" } ] } ] }, { "uniprot_ac": "A6QLJ0", "gene_name": "ERCC2", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] } ] }, { "uniprot_ac": "A6QQR4", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] } ] }, { "uniprot_ac": "A7YSY2", "gene_name": "AFG2B", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] } ] }, { "uniprot_ac": "A7Z019", "gene_name": "SMARCA4", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A7Z019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7Z019" } ] } ] }, { "uniprot_ac": "E1B7X9", "gene_name": "SMARCAD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1B7X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7X9" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B9N7", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] } ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BAN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAN8" } ] } ] }, { "uniprot_ac": "E1BAS6", "gene_name": "SETX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] } ] }, { "uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "O18956", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] } ] }, { "uniprot_ac": "P09487", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.9.1.1", "activity": "N-phosphocreatine + H2O = creatine + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] } ] }, { "uniprot_ac": "P19120", "gene_name": "HSPA8", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] } ] }, { "uniprot_ac": "P35071", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "P35071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35071" } ] } ] }, { "uniprot_ac": "P60712", "gene_name": "ACTB", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P60712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P60712" } ] } ] }, { "uniprot_ac": "P62739", "gene_name": "ACTA2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P62739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62739" } ] } ] }, { "uniprot_ac": "P63258", "gene_name": "ACTG1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P63258" } ] } ] }, { "uniprot_ac": "P68138", "gene_name": "ACTA1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68138" } ] } ] }, { "uniprot_ac": "Q05B79", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": 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"uniprot_ac": "A0ABI0NZT7", "uniprot_id": "A0ABI0NZT7_BOVIN", "mass": { "chemical_mass": 226829.0, "monoisotopic_mass": 226829.0 }, "refseq": { "ac": "NP_001179500", "name": "PHD finger protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179500" }, "gene_names": [ { "name": "PHF3", "type": "recommended", "evidence": [ { "id": "A0ABI0NZT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT7" } ] }, { "name": "PHF3", "type": "synonym", "evidence": [ { "id": "NP_001179500", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179500" } ] } ], "protein_names": [ { "name": "PHD finger protein 3", "type": "synonym", "evidence": [ { "id": "NP_001179500", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179500" }, { "id": "A0ABI0NZT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZT7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PHF3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT7", "locus": { "chromosome": "9", "start_pos": 655879, "end_pos": 563410, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019139", "url": "https://www.ensembl.org/id/ENSBTAG00000019139" } ] } } ], "crossref": [ { "id": "ENSBTAG00000019139", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019139", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15638", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15638", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21548", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21548", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "522928", "url": "https://www.ncbi.nlm.nih.gov/gene/522928", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012921", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G5E5M1", "url": "https://www.orthodb.org/?gene=G5E5M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11477", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11477", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11477:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11477:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07500", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07500", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07744", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07744", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179500", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179500", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T2E9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T2E9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZT7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZT7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5M1", "url": "https://www.uniprot.org/uniprotkb/G5E5M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5M1-1", "url": "https://www.uniprot.org/uniprotkb/G5E5M1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSTSQNVLEDSLKNMLSDKDPMLGSASNQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDDEELILPNRNLRDKVEENSVRSPRKSPRLMAQEQVRNLRQSTIAKRSNAAPLNSTKKASGKTVSAPKVGVKQPERCQIKEEAGTSPKSEHQKESRKSNRHSGQVEAAVSSCLEMKDEAGLDSEQKCNNQGEANVPSHELNSPLLSETCINIEKKKSETLECKTKSVSPLFKFSDKEEDGRNDSISGKMDETIVEEMKAEEVEQESKVTVKLPHKDDNVIKEPASCDAFSGSSACTNPNKTEKNFVSLSGSVDKVSECSLELQDSMEVAVKAKNSPLFQRNEIEMAYCKGTESNDKQLEGTRFNKSNLEVVNTGAFEPESNTLENAICDAPDQNSEQLNIVEDIKMEFHETATLQDDRDSQSSSVSSLESKNIKSKHKKPVIHPKQTLTTDTQKKVATAKHELMHNKTKANVKSVKRNADESESKQNFHRPVKVRKKQVDKDSKIQSCISGVKSVKNQTHSIFKKTSQDQNLVQISKPLTHSMSDKPHGHPSCSKEPHHSVQTGHSLQASQKQCHKPQQPTLAARTNSHAKEELEHAGGGEHLKEEEKLKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATVKREGLDHSSSFECKYIWTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEIADPDILRNQAKVEIHSEDKAMEYEKLGLPKHTTTNDKTKYVDDTVKHKVKILKRESGEGKNSSDCRDSEIKKWQLAPFRKMGQPVLPRRSSEEKSEKMTKESTTVICTGEKASKPGAHEKQEIKKKKTEKGLPGVHPPAVPASKPSADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPTANKSMEKTEGSEKQKGEVDLMSKDTTSQHRQHLFDLNCKICIGRMAPPADDLSPKKVKVVVGVSRKHSDNEAESIADALSSTSNILASEFFEEEKQESPKSTFSPAPRPEMPGTVEVECTFLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEKIKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGAMDKIPHPLVPFDGPGLELHRPNLLLGLIIRQRLKRQHSAGAGAGRTAETSDSAPVTVPPDKKSKTEVSTEGAAEEESDFFNSFTTVLHKQRNKPQQTLQEDLPTVIEPLLEVTKQEPPKPLRFLPGVLIGWENQPSTLELANKPLPVDDILQSLLGTAGQMYEQAQLGTEQNTPKEIPFINEQANPKAGTIDTGEATGGEAKEVKVKGDSPSELTDNAIGEETSALGVSSVSAGPLTSLSLRGKPPDVSTEAFLTNLSIQSKQEDTVESKERVLKQLLQDQENNLQDNRTSNTSPPCRSNVGRGNVDGNVSCSENAVTNTTRAPQFINLKRDPRQAAGRSQQVTTPENREGEGCRHGEKPPLPGPSHLTEQSSVEEKMPSVEKSPCVQHNDDSGAVQDSPSVENIQSSQVEQAKPLQEILMQNIETVHPFRRGSAATASHFEVGNTCQSEFPSKSISFTSRSTSPRTSANFSPIRPQQPSLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPPPGFGFAPNPLVPWPPVVHLTGQPQRMMGPLSQASRYLGPQNFYQVKDIRRPERRHSDPWGRQDQQQPDRPFNRGKGDRQRFYSDSHHLRRERHEKEWEQEPERHRRRDRAQDKDRDRKGRDEGHKDKERARLPHGERGADGRANRESRSADRKPDKPKGEDQEKDKEREKSKHREGEKDRDRYHKDRDHAERAKSKR", "length": 2025, "header": "tr|A0ABI0NZT7-1|A0ABI0NZT7_BOVIN Isoform 1 of PHD finger protein 3 OS=Bos taurus OX=9913 GN=PHF3 PE=4 SV=1 CANONICAL=A0ABI0NZT7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T2E9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT7/entry#A0AAA9T2E9-1", "sequence": { "sequence": "MGFSWRNNGVGCQFLLQGIFPTQELPLSLLHYSVCLTALGLSCSAPVFLWLFSSVVAAWSFVVLRPVTSEFPEKGSNPVPCIERAERHTEVFMDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSTSQNVLEDSLKNMLSDKDPMLGSASNQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDDEELILPNRNLRDKVEENSVRSPRKSPRLMAQEQVRNLRQSTIAKRSNAAPLNSTKKASGKTVSAPKVGVKQPERCQIKEEAGTSPKSEHQKESRKSNRHSGQVEAAVSSCLEMKDEAGLDSEQKCNNQGEANVPSHELNSPLLSETCINIEKKKSETLECKTKSVSPLFKFSDKEEDGRNDSISGKMDETIVEEMKAEEVEQESKVTVKLPHKDDNVIKEPASCDAFSGSSACTNPNKTEKNFVSLSGSVDKVSECSLELQDSMEVAVKAKNSPLFQRNEIEMAYCKGTESNDKQLEGTRFNKSNLEVVNTGAFEPESNTLENAICDAPDQNSEQLNIVEDIKMEFHETATLQDDRDSQSSSVSSLESKNIKSKHKKPVIHPKQTLTTDTQKKVATAKHELMHNKTKANVKSVKRNADESESKQNFHRPVKVRKKQVDKDSKIQSCISGVKSVKNQTHSIFKKTSQDQNLVQISKPLTHSMSDKPHGHPSCSKEPHHSVQTGHSLQASQKQCHKPQQPTLAARTNSHAKEELEHAGGGEHLKEEEKLKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATVKREGLDHSSSFECKYIWTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEIADPDILRNQAKVEIHSEDKAMEYEKLGLPKHTTTNDKTKYVDDTVKHKVKILKRESGEGKNSSDCRDSEIKKWQLAPFRKMGQPVLPRRSSEEKSEKMTKESTTVICTGEKASKPGAHEKQEIKKKKTEKGLPGVHPPAVPASKPSADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPTANKSMEKTEGSEKQKGEVDLMSKDTTSQHRQHLFDLNCKICIGRMAPPADDLSPKKVKVVVGVSRKHSDNEAESIADALSSTSNILASEFFEEEKQESPKSTFSPAPRPEMPGTVEVECTFLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEKIKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGAMDKIPHPLVPFDGPGLELHRPNLLLGLIIRQRLKRQHSAGAGAGRTAETSDSAPVTVPPDKKSKTEVSTEGAAEEESDFFNSFTTVLHKQRNKPQQTLQEDLPTVIEPLLEVTKQEPPKPLRFLPGVLIGWENQPSTLELANKPLPVDDILQSLLGTAGQMYEQAQLGTEQNTPKEIPFINEQANPKAGTIDTGEATGGEAKEVKVKGDSPSELTDNAIGEETSALGVSSVSAGPLTSLSLRGKPPDVSTEAFLTNLSIQSKQEDTVESKERVLKQLLQDQENNLQDNRTSNTSPPCRSNVGRGNVDGNVSCSENAVTNTTRAPQFINLKRDPRQAAGRSQQVTTPENREGEGCRHGEKPPLPGPSHLTEQSSVEEKMPSVEKSPCVQHNDDSGAVQDSPSVENIQSSQVEQAKPLQEILMQNIETVHPFRRGSAATASHFEVGNTCQSEFPSKSISFTSRSTSPRTSANFSPIRPQQPSLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPPPGFGFAPNPLVPWPPVVHLTGQPQRMMGPLSQASRYLGPQNFYQVKDIRRPERRHSDPWGRQDQQQPDRPFNRGKGDRQRFYSDSHHLRRERHEKEWEQEPERHRRRDRAQDKDRDRKGRDEGHKDKERARLPHGERGADGRANRESRSADRKPDKPKGEDQEKDKEREKSKHREGEKDRDRYHKDRDHAERAKSKR", "length": 2117, "header": "tr|A0AAA9T2E9-1|A0ABI0NZT7_BOVIN Computationally mapped isoform of PHD finger protein 3 OS=Bos taurus OX=9913 GN=PHF3 PE=4 SV=1 CANONICAL=A0ABI0NZT7-1" }, "locus": { "chromosome": "9", "start_pos": 654895, "end_pos": 572542, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094534.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094534.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091903.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091903.1" } ] } }, { "isoform_ac": "A0ABI0NZT7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT7/entry#A0ABI0NZT7-1", "sequence": { "sequence": "MDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSTSQNVLEDSLKNMLSDKDPMLGSASNQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDDEELILPNRNLRDKVEENSVRSPRKSPRLMAQEQVRNLRQSTIAKRSNAAPLNSTKKASGKTVSAPKVGVKQPERCQIKEEAGTSPKSEHQKESRKSNRHSGQVEAAVSSCLEMKDEAGLDSEQKCNNQGEANVPSHELNSPLLSETCINIEKKKSETLECKTKSVSPLFKFSDKEEDGRNDSISGKMDETIVEEMKAEEVEQESKVTVKLPHKDDNVIKEPASCDAFSGSSACTNPNKTEKNFVSLSGSVDKVSECSLELQDSMEVAVKAKNSPLFQRNEIEMAYCKGTESNDKQLEGTRFNKSNLEVVNTGAFEPESNTLENAICDAPDQNSEQLNIVEDIKMEFHETATLQDDRDSQSSSVSSLESKNIKSKHKKPVIHPKQTLTTDTQKKVATAKHELMHNKTKANVKSVKRNADESESKQNFHRPVKVRKKQVDKDSKIQSCISGVKSVKNQTHSIFKKTSQDQNLVQISKPLTHSMSDKPHGHPSCSKEPHHSVQTGHSLQASQKQCHKPQQPTLAARTNSHAKEELEHAGGGEHLKEEEKLKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATVKREGLDHSSSFECKYIWTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEIADPDILRNQAKVEIHSEDKAMEYEKLGLPKHTTTNDKTKYVDDTVKHKVKILKRESGEGKNSSDCRDSEIKKWQLAPFRKMGQPVLPRRSSEEKSEKMTKESTTVICTGEKASKPGAHEKQEIKKKKTEKGLPGVHPPAVPASKPSADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPTANKSMEKTEGSEKQKGEVDLMSKDTTSQHRQHLFDLNCKICIGRMAPPADDLSPKKVKVVVGVSRKHSDNEAESIADALSSTSNILASEFFEEEKQESPKSTFSPAPRPEMPGTVEVECTFLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEKIKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGAMDKIPHPLVPFDGPGLELHRPNLLLGLIIRQRLKRQHSAGAGAGRTAETSDSAPVTVPPDKKSKTEVSTEGAAEEESDFFNSFTTVLHKQRNKPQQTLQEDLPTVIEPLLEVTKQEPPKPLRFLPGVLIGWENQPSTLELANKPLPVDDILQSLLGTAGQMYEQAQLGTEQNTPKEIPFINEQANPKAGTIDTGEATGGEAKEVKVKGDSPSELTDNAIGEETSALGVSSVSAGPLTSLSLRGKPPDVSTEAFLTNLSIQSKQEDTVESKERVLKQLLQDQENNLQDNRTSNTSPPCRSNVGRGNVDGNVSCSENAVTNTTRAPQFINLKRDPRQAAGRSQQVTTPENREGEGCRHGEKPPLPGPSHLTEQSSVEEKMPSVEKSPCVQHNDDSGAVQDSPSVENIQSSQVEQAKPLQEILMQNIETVHPFRRGSAATASHFEVGNTCQSEFPSKSISFTSRSTSPRTSANFSPIRPQQPSLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPPPGFGFAPNPLVPWPPVVHLTGQPQRMMGPLSQASRYLGPQNFYQVKDIRRPERRHSDPWGRQDQQQPDRPFNRGKGDRQRFYSDSHHLRRERHEKEWEQEPERHRRRDRAQDKDRDRKGRDEGHKDKERARLPHGERGADGRANRESRSADRKPDKPKGEDQEKDKEREKSKHREGEKDRDRYHKDRDHAERAKSKR", "length": 2025, "header": "tr|A0ABI0NZT7-1|A0ABI0NZT7_BOVIN Isoform 1 of PHD finger protein 3 OS=Bos taurus OX=9913 GN=PHF3 PE=4 SV=1 CANONICAL=A0ABI0NZT7-1" }, "locus": { "chromosome": "9", "start_pos": 654895, "end_pos": 576884, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137539.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137539.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107284.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107284.1" } ] } }, { "isoform_ac": "G5E5M1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT7/entry#G5E5M1-1", "sequence": { "sequence": "MKQVGNIFGLRFSMAERHTEVFMDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSTSQNVLEDSLKNMLSDKDPMLGSASNQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDDEELILPNRNLRDKVEENSVRSPRKSPRLMAQEQVRNLRQSTIAKRSNAAPLNSTKKASGKTVSAPKVGVKQPERCQIKEEAGTSPKSEHQKESRKSNRHSGQVEAAVSSCLEMKDEAGLDSEQKCNNQGEANVPSHELNSPLLSETCINIEKKKSETLECKTKSVSPLFKFSDKEEDGRNDSISGKMDETIVEEMKAEEVEQESKVTVKLPHKDDNVIKEPASCDAFSGSSACTNPNKTEKNFVSLSGSVDKVSECSLELQDSMEVAVKAKNSPLFQRNEIEMAYCKGTESNDKQLEGTRFNKSNLEVVNTGAFEPESNTLENAICDAPDQNSEQLNIVEDIKMEFHETATLQDDRDSQSSSVSSLESKNIKSKHKKPVIHPKQTLTTDTQKKVATAKHELMHNKTKANVKSVKRNADESESKQNFHRPVKVRKKQVDKDSKIQSCISGVKSVKNQTHSIFKKTSQDQNLVQISKPLTHSMSDKPHGHPSCSKEPHHSVQTGHSLQASQKQCHKPQQPTLAARTNSHAKEELEHAGGGEHLKEEEKLKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATVKREGLDHSSSFECKYIWTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEIADPDILRNQAKVEIHSEDKAMEYEKLGLPKHTTTNDKTKYVDDTVKHKVKILKRESGEGKNSSDCRDSEIKKWQLAPFRKMGQPVLPRRSSEEKSEKMTKESTTVICTGEKASKPGAHEKQEIKKKKTEKGLPGVHPPAVPASKPSADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPTANKSMEKTEGSEKQKGEVDLMSKDTTSQHRQHLFDLNCKICIGRMAPPADDLSPKKVKVVVGVSRKHSDNEAESIADALSSTSNILASEFFEEEKQESPKSTFSPAPRPEMPGTVEVECTFLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEKIKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGAMDKIPHPLVPFDGPGLELHRPNLLLGLIIRQRLKRQHSAGAGAGRTAETSDSAPVTVPPDKKSKTEVSTEGAAEEESDFFNSFTTVLHKQRNKPQQTLQEDLPTVIEPLLEVTKQEPPKPLRFLPGVLIGWENQPSTLELANKPLPVDDILQSLLGTAGQMYEQAQLGTEQNTPKEIPFINEQANPKAGTIDTGEATGGEAKEVKVKGDSPSELTDNAIGEETSALGVSSVSAGPLTSLSLRGKPPDVSTEAFLTNLSIQSKQEDTVESKERVLKQLLQDQENNLQDNRTSNTSPPCRSNVGRGNVDGNVSCSENAVTNTTRAPQFINLKRDPRQAAGRSQQVTTPENREGEGCRHGEKPPLPGPSHLTEQSSVEEKMPSVEKSPCVQHNDDSGAVQDSPSVENIQSSQVEQAKPLQEILMQNIETVHPFRRGSAATASHFEVGNTCQSEFPSKSISFTSRSTSPRTSANFSPIRPQQPSLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPPPGFGFAPNPLVPWPPVVHLTGQPQRMMGPLSQASRYLGPQNFYQVKDIRRPERRHSDPWGRQDQQQPDRPFNRGKGDRQRFYSDSHHLRRERHEKEWEQEPERHRRRDRAQDKDRDRKGRDEGHKDKERARLPHGERGADGRANRESRSADRKPDKPKGEDQEKDKEREKSKHREGEKDRDRYHKDRDHAERAKSKR", "length": 2047, "header": "tr|G5E5M1-1|A0ABI0NZT7_BOVIN Computationally mapped isoform of PHD finger protein 3 OS=Bos taurus OX=9913 GN=PHF3 PE=4 SV=3 CANONICAL=A0ABI0NZT7-1" }, "locus": { "chromosome": "9", "start_pos": 654895, "end_pos": 571668, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025476.7", "url": "https://www.ensembl.org/id/ENSBTAT00000025476.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025476.7", "url": "https://www.ensembl.org/id/ENSBTAP00000025476.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZT7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZT7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZT7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1074, "end_pos": 1076, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1566, "end_pos": 1568, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1598, "end_pos": 1600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1602, "end_pos": 1604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1619, "end_pos": 1621, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1629, "end_pos": 1631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1780, "end_pos": 1782, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 830, "end_pos": 832, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NZT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT7" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 707, "end_pos": 762, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NZT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT7" }, { "id": "PS51321", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51321" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TFIIS central", "eco_id": "ECO_0000259", "start_pos": 919, "end_pos": 1038, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1074, "end_pos": 1076 }, { "start_pos": 1566, "end_pos": 1568 }, { "start_pos": 156, "end_pos": 158 }, { "start_pos": 1598, "end_pos": 1600 }, { "start_pos": 1602, "end_pos": 1604 }, { "start_pos": 1619, "end_pos": 1621 }, { "start_pos": 1629, "end_pos": 1631 }, { "start_pos": 1780, "end_pos": 1782 }, { "start_pos": 284, "end_pos": 286 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 559, "end_pos": 561 }, { "start_pos": 830, "end_pos": 832 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NXT5-1", "uniprot_ac": "A0ABI0NXT5", "uniprot_id": "A0ABI0NXT5_BOVIN", "mass": { "chemical_mass": 83718.0, "monoisotopic_mass": 83718.0 }, "refseq": {}, "gene_names": [ { "name": "POLI", "type": "recommended", "evidence": [ { "id": "A0ABI0NXT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5" } ] } ], "protein_names": [ { "name": "DNA polymerase iota", "type": "recommended", "evidence": [ { "id": "A0ABI0NXT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.7", "type": "synonym", "evidence": [ { "id": "A0ABI0NXT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NKY4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKY4#function" }, { "database": "UniProtKB", "id": "ARBA00059122", "url": "https://www.uniprot.org/uniprotkb/ARBA00059122#function" }, { "database": "UniProtKB", "id": "A0ABI0NXT5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5#function" }, { "database": "UniProtKB", "id": "A0AAA9TVK9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVK9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXT5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "POLI", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5", "locus": { "chromosome": "24", "start_pos": 53715912, "end_pos": 53691914, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009129", "url": "https://www.ensembl.org/id/ENSBTAG00000009129" } ] } } ], "crossref": [ { "id": "ENSBTAG00000009129", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009129", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01703", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01703", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053848", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053848", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MHR0", "url": "https://www.orthodb.org/?gene=F1MHR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46404:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46404:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00817", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00817", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14377", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14377", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21999", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21999", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5656121", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5656121", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5656169", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5656169", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "22508", "url": "https://www.rhea-db.org/rhea/22508", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TL11", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TL11-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVK9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVK9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKY4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKY4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXT5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXT5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MHR0", "url": "https://www.uniprot.org/uniprotkb/F1MHR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MHR0-1", "url": "https://www.uniprot.org/uniprotkb/F1MHR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKRGVEPEEAGGGDEEADETRAMERAEAGAPGGWPGALEPDELDDLPWLHDELEPAGSSSCRVIVHVDLDCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMSVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLEQLQSDELSALTVSGHVYNNQPVNPRDTLHIRLLVGSQIVAEMREAMYQQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESSQELIHSLNHIKEMPGIGYKTTKRLEALGISSVRDLQTFPSKVLEKELGISVAQRIQKLSFGEDDSPVTPSGPPQSFSEEDSFKKCSSEVEAKTKIEELLASLLNRVCQDGRKPHTIRLIIRRYSSEKHYNRESRQCPIPSHIIQKLGAGNYDVMTPMVDILMKLFRNMVNVKVPFHLTLLSVCFCNLKSLNTAKKGTMDYYLTPSLSTTSHAGKRSFKMKDCHMEDFSKDKETNRDFLPTGRIESTRTGESPPDPINSSKEKDSNEFPVSLLPEDIDQEVFKQLPVDIQEEILSGKSREKVQGKGSLSCPLRASRGVLSLFSTKQKQDSSLNPKDHVPKSKQVSSVSPCEPGTSGGSSSSYVSSQKEYSHYLDSSLKDERMSQGPKESQRFHFSNTNPAVSVFHSFPNLQSEQLLSKNRTTDSHKQPVATVSRHEGLKENREQESPDEKIAFPSDIDPEVFYELPEEVQKELLADWKRTGSDFHTT", "length": 747, "header": "tr|A0ABI0NXT5-1|A0ABI0NXT5_BOVIN Isoform 1 of DNA polymerase iota OS=Bos taurus OX=9913 GN=POLI PE=3 SV=1 CANONICAL=A0ABI0NXT5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TL11-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5/entry#A0AAA9TL11-1", "sequence": { "sequence": "MERAEAGAPGGWPGALEPDELDDLPWWVQQKYLVVTCNYEARKLGVKKLMSVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLEQLQSDELSALTVSGHVYNNQPVNPRDTLHIRLLVGSQIVAEMREAMYQQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESSQELIHSLNHIKEMPGIGYKTTKRLEALGISSVRDLQTFPSKVLEKELGISVAQRIQKLSFGEDDSPVTPSGPPQSFSEEDSFKKCSSEVEAKTKIEELLASLLNRVCQDGRKPHTIRLIIRRYSSEKHYNRESRQCPIPSHIIQKLGAGNYDVMTPMVDILMKLFRNMVNVKVPFHLTLLSVCFCNLKSLNTAKKGTMDYYLTPSLSTTSHAGKRSFKMKDCHMEDFSKDKETNRDFLPTGRIESTRTGESPPDPINSSKEKDSNEFPVSLLPEDIDQEVFKQLPVDIQEEILSGKSREKVQGKGSLSCPLRASRGVLSLFSTKQKQDSSLNPKDHVPKSKQVSSVSPCEPGTSGGSSSSYVSSQKEYSHYLDSSLKDERMSQGPKESQRFHFSNTNPAVSVFHSFPNLQSEQLLSKNRTTDSHKQPVATVSRHEGLKENREQESPDEKIAFPSDIDPEVFYELPEEVQKELLADWKRTGSDFHTT", "length": 683, "header": "tr|A0AAA9TL11-1|A0ABI0NXT5_BOVIN Computationally mapped isoform of DNA polymerase iota OS=Bos taurus OX=9913 GN=POLI PE=3 SV=1 CANONICAL=A0ABI0NXT5-1" }, "locus": { "chromosome": "24", "start_pos": 53715660, "end_pos": 53691927, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109257.2", "url": "https://www.ensembl.org/id/ENSBTAT00000109257.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099106.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099106.1" } ] } }, { "isoform_ac": "A0AAA9TVK9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5/entry#A0AAA9TVK9-1", "sequence": { "sequence": "MEWTVAHRAPLSMEFSSQEYWIHDELEPAGSSSCRVIVHVDLDCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMSVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLEQLQSDELSALTVSGHVYNNQPVNPRDTLHIRLLVGSQIVAEMREAMYQQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESSQELIHSLNHIKEMPGIGYKTTKRLEALGISSVRDLQTFPSKVLEKELGISVAQRIQKLSFGEDDSPVTPSGPPQSFSEEDSFKKCSSEVEAKTKIEELLASLLNRVCQDGRKPHTIRLIIRRYSSEKHYNRESRQCPIPSHIIQKLGAGNYDVMTPMVDILMKLFRNMVNVKVPFHLTLLSVCFCNLKSLNTAKKGTMDYYLTPSLSTTSHAGKRSFKMKDCHMEDFSKDKETNRDFLPTGRIESTRTGESPPDPINSSKEKDSNEFPVSLLPEDIDQEVFKQLPVDIQEEILSGKSREKVQGKGSLSCPLRASRGVLSLFSTKQKQDSSLNPKDHVPKSKQVSSVSPCEPGTSGGSSSSYVSSQKEYSHYLDSSLKDERMSQGPKESQRFHFSNTNPAVSVFHSFPNLQSEQLLSKNRTTDSHKQPVATVSRHEGLKENREQESPDEKIAFPSDIDPEVFYELPEEVQKELLADWKRTGSDFHTT", "length": 719, "header": "tr|A0AAA9TVK9-1|A0ABI0NXT5_BOVIN Computationally mapped isoform of DNA polymerase iota OS=Bos taurus OX=9913 GN=POLI PE=3 SV=1 CANONICAL=A0ABI0NXT5-1" }, "locus": { "chromosome": "24", "start_pos": 53715660, "end_pos": 53693081, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094980.2", "url": "https://www.ensembl.org/id/ENSBTAT00000094980.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102394.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102394.1" } ] } }, { "isoform_ac": "A0ABI0NKY4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5/entry#A0ABI0NKY4-1", "sequence": { "sequence": "MCFFHLVAYCATVHDELEPAGSSSCRVIVHVDLDCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMSVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLEQLQSDELSALTVSGHVYNNQPVNPRDTLHIRLLVGSQIVAEMREAMYQQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESSQELIHSLNHIKEMPGIGYKTTKRLEALGISSVRDLQTFPSKVLEKELGISVAQRIQKLSFGEDDSPVTPSGPPQSFSEEDSFKKCSSEVEAKTKIEELLASLLNRVCQDGRKPHTIRLIIRRYSSEKHYNRESRQCPIPSHIIQKLGAGNYDVMTPMVDILMKLFRNMVNVKVPFHLTLLSVCFCNLKSLNTAKKGTMDYYLTPSLSTTSHAGKRSFKMKDCHMEDFSKDKETNRDFLPTGRIESTRTGESPPDPINSSKEKDSNEFPVSLLPEDIDQEVFKQLPVDIQEEILSGKSREKVQGKGSLSCPLRASRGVLSLFSTKQKQDSSLNPKDHVPKSKQVSSVSPCEPGTSGGSSSSYVSSQKEYSHYLDSSLKDERMSQGPKESQRFHFSNTNPAVSVFHSFPNLQSEQLLSKNRTTDSHKQPVATVSRHEGLKENREQESPDEKIAFPSDIDPEVFYELPEEVQKELLADWKRTGSDFHTT", "length": 710, "header": "tr|A0ABI0NKY4-1|A0ABI0NXT5_BOVIN Computationally mapped isoform of DNA polymerase iota OS=Bos taurus OX=9913 GN=POLI PE=3 SV=1 CANONICAL=A0ABI0NXT5-1" }, "locus": { "chromosome": "24", "start_pos": 53715660, "end_pos": 53693639, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145364.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145364.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105522.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105522.1" } ] } }, { "isoform_ac": "A0ABI0NXT5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5/entry#A0ABI0NXT5-1", "sequence": { "sequence": "MEKRGVEPEEAGGGDEEADETRAMERAEAGAPGGWPGALEPDELDDLPWLHDELEPAGSSSCRVIVHVDLDCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMSVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLEQLQSDELSALTVSGHVYNNQPVNPRDTLHIRLLVGSQIVAEMREAMYQQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESSQELIHSLNHIKEMPGIGYKTTKRLEALGISSVRDLQTFPSKVLEKELGISVAQRIQKLSFGEDDSPVTPSGPPQSFSEEDSFKKCSSEVEAKTKIEELLASLLNRVCQDGRKPHTIRLIIRRYSSEKHYNRESRQCPIPSHIIQKLGAGNYDVMTPMVDILMKLFRNMVNVKVPFHLTLLSVCFCNLKSLNTAKKGTMDYYLTPSLSTTSHAGKRSFKMKDCHMEDFSKDKETNRDFLPTGRIESTRTGESPPDPINSSKEKDSNEFPVSLLPEDIDQEVFKQLPVDIQEEILSGKSREKVQGKGSLSCPLRASRGVLSLFSTKQKQDSSLNPKDHVPKSKQVSSVSPCEPGTSGGSSSSYVSSQKEYSHYLDSSLKDERMSQGPKESQRFHFSNTNPAVSVFHSFPNLQSEQLLSKNRTTDSHKQPVATVSRHEGLKENREQESPDEKIAFPSDIDPEVFYELPEEVQKELLADWKRTGSDFHTT", "length": 747, "header": "tr|A0ABI0NXT5-1|A0ABI0NXT5_BOVIN Isoform 1 of DNA polymerase iota OS=Bos taurus OX=9913 GN=POLI PE=3 SV=1 CANONICAL=A0ABI0NXT5-1" }, "locus": { "chromosome": "24", "start_pos": 53715660, "end_pos": 53691858, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149043.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149043.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104914.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104914.1" } ] } }, { "isoform_ac": "F1MHR0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5/entry#F1MHR0-1", "sequence": { "sequence": "MSVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLEQLQSDELSALTVSGHVYNNQPVNPRDTLHIRLLVGSQIVAEMREAMYQQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESSQELIHSLNHIKEMPGIGYKTTKRLEALGISSVRDLQTFPSKVLEKELGISVAQRIQKLSFGEDDSPVTPSGPPQSFSEEDSFKKCSSEVEAKTKIEELLASLLNRVCQDGRKPHTIRLIIRRYSSEKHYNRESRQCPIPSHIIQKLGAGNYDVMTPMVDILMKLFRNMVNVKVPFHLTLLSVCFCNLKSLNTAKKGTMDYYLTPSLSTTSHAGKRSFKMKDCHMEDFSKDKETNRDFLPTGRIESTRTGESPPDPINSSKEKDSNEFPVSLLPEDIDQEVFKQLPVDIQEEILSGKSREKVQGKGSLSCPLRASRGVLSLFSTKQKQDSSLNPKDHVPKSKQVSSVSPCEPGTSGGSSSSYVSSQKEYSHYLDSSLKDERMSQGPKESQRFHFSNTNPAVSVFHSFPNLQSEQLLSKNRTTDSHKQPVATVSRHEGLKENREQESPDEKIAFPSDIDPEVFYELPEEVQKELLADWKRTGSDFHTHK", "length": 635, "header": "tr|F1MHR0-1|A0ABI0NXT5_BOVIN Computationally mapped isoform of DNA polymerase iota OS=Bos taurus OX=9913 GN=POLI PE=3 SV=5 CANONICAL=A0ABI0NXT5-1" }, "locus": { "chromosome": "24", "start_pos": 53715664, "end_pos": 53697198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012034.7", "url": "https://www.ensembl.org/id/ENSBTAT00000012034.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012034.7", "url": "https://www.ensembl.org/id/ENSBTAP00000012034.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 329, "start_aa": "Thr", "end_pos": 329, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr329", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-5656121", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5656121", "resource": "Reactome", "description": "Translesion synthesis by POLI" }, { "id": "R-BTA-5656169", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5656169", "resource": "Reactome", "description": "Termination of translesion DNA synthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-directed DNA polymerase activity", "id": "GO:0003887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003887", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXT5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXT5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXT5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXT5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5" } ], "pmid": "" }, { "name": "translesion synthesis", "id": "GO:0019985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019985", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXT5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXT5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 679, "end_pos": 681, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22508", "name": "", "equation": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BHH1-1", "A0A3Q1M493-1", "E1BPY8-1", "Q08DZ8-1", "Q27958-1", "E1BNZ6-1", "A0AAA9SFP0-1", "A0AAA9THK8-1", "P06526-1", "P28339-1", "Q27ID4-1", "A0AAA9STI1-1", "F1MPJ5-1", "A0AAA9RXS9-1", "E1BDI3-1", "E1BDC2-1", "F1MZ79-1", "A0ABI0NXT5-1" ], "evidence": [ { "id": "22508", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22508" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1M493", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] } ] }, { "uniprot_ac": "A0AAA9RXS9", "gene_name": "POLK", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0AAA9RXS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXS9" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0AAA9RXS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXS9" } ] } ] }, { "uniprot_ac": "A0AAA9SFP0", "gene_name": "POLE", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0AAA9SFP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFP0" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0AAA9SFP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFP0" } ] } ] }, { "uniprot_ac": "A0AAA9STI1", "gene_name": "TERT", "activity": [ { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0AAA9STI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STI1" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0AAA9STI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STI1" } ] } ] }, { "uniprot_ac": "A0AAA9THK8", "gene_name": "POLA1", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0AAA9THK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THK8" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0AAA9THK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THK8" } ] } ] }, { "uniprot_ac": "A0ABI0NXT5", "gene_name": "POLI", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0ABI0NXT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0ABI0NXT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXT5" } ] } ] }, { "uniprot_ac": "E1BDC2", "gene_name": "POLN", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "E1BDC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDC2" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "E1BDC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDC2" } ] } ] }, { "uniprot_ac": "E1BDI3", "gene_name": "POLG", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "E1BDI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDI3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "E1BDI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDI3" } ] } ] }, { "uniprot_ac": "E1BHH1", "gene_name": "POLL", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "E1BHH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHH1" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "E1BHH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHH1" } ] } ] }, { "uniprot_ac": "E1BNZ6", "gene_name": "POLD1", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "E1BNZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNZ6" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "E1BNZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNZ6" } ] } ] }, { "uniprot_ac": "E1BPY8", "gene_name": "REV3L", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "E1BPY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPY8" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "E1BPY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPY8" } ] } ] }, { "uniprot_ac": "F1MPJ5", "gene_name": "POLM", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "F1MPJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPJ5" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "F1MPJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPJ5" } ] } ] }, { "uniprot_ac": "F1MZ79", "gene_name": "POLH", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "F1MZ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MZ79" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "F1MZ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MZ79" } ] } ] }, { "uniprot_ac": "P06526", "gene_name": "DNTT", "activity": [ { "ec_number": "2.7.7.31", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "P06526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P06526" } ] }, { "ec_number": "2.7.7.31", "activity": "", "evidence": [ { "id": "P06526", "database": 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"MVELPGYSLSGVFASFFFMLLSMKQSDDFRVTGSAHPILAMVGEDALLTCQLLPKRTAMHMEVRWYRSEPSTPVFLYRDGDEVTEIQMEEYRGRVEWIEDGITEGSVSLKIHSLQPSDHGQYWCRVKDDNYLAETSLLLQVASLGSDPYIHMDGSVESGLQLVCTAKGWFPEPQVSWQDIKGEKLLTFSNYNFQDEDGLFYVESTLVVRDASTEAVSCFIHNPSLTEEKGSDVSIPVCLLYLTASLKVIGPSQPILVRVGEDIQLTCSLAPKTDAQSMEVRWVRSHRHPAVYVYTDGARVAGEQMAEYRGRTALLSDAISEGRLTLQINDARTSDDGKYQCLFEKDGVYQEADLDLKIIGLGSSPQISMEGPKDGEVKLKCTSEGWFPQPQVQWRDMEGNTIPSSSQDLTQGSQGLFQVEAFLLVTNSSIVNVTCSISSPLLGEEKKTTFYASESRMIYSWNILLIWGLLLLLLVGVVGLIWRKNCRKGSSESFLHPKESQQHLQGEHKDLEKVLKSSEVRLRDTSE", "length": 527, "header": "tr|A0ABI0NWP8-1|A0ABI0NWP8_BOVIN Isoform 1 of Butyrophilin like 2 OS=Bos taurus OX=9913 GN=BTNL2 PE=4 SV=1 CANONICAL=A0ABI0NWP8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NWP8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWP8/entry#A0ABI0NWP8-1", "sequence": { "sequence": 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"strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049415.5", "url": "https://www.ensembl.org/id/ENSBTAT00000049415.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046309.3", "url": "https://www.ensembl.org/id/ENSBTAP00000046309.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWP8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWP8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWP8", "url": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NV40-1", "uniprot_ac": "A0ABI0NV40", "uniprot_id": "A0ABI0NV40_BOVIN", "mass": { "chemical_mass": 65073.0, "monoisotopic_mass": 65073.0 }, "refseq": { "ac": "XP_005221632", "name": "prolactin receptor isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221632" }, "gene_names": [ { "name": "PRLR", "type": "recommended", "evidence": [ { "id": "A0ABI0NV40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40" } ] }, { "name": "PRLR", "type": "synonym", "evidence": [ { "id": "XP_005221632", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221632" } ] }, { "name": "SPRLR", "type": "synonym", "evidence": [ { "id": "XP_005221632", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221632" } ] } ], "protein_names": [ { "name": "Prolactin receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NV40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40/entry#names_and_taxonomy" } ] }, { "name": "PRL-R", "type": "synonym", "evidence": [ { "id": "A0ABI0NV40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40/entry#names_and_taxonomy" } ] }, { "name": "prolactin receptor isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005221632", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221632" } ] } ], "function": [ { "annotation": "This is a receptor for the anterior pituitary hormone prolactin.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MJ05", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJ05#function" }, { "database": "UniProtKB", "id": "RU365035", "url": "https://www.uniprot.org/uniprotkb/RU365035#function" }, { "database": "UniProtKB", "id": "ARBA00053754", "url": "https://www.uniprot.org/uniprotkb/ARBA00053754#function" }, { "database": "UniProtKB", "id": "A0ABI0NV40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40#function" }, { "database": "UniProtKB", "id": "A0A3Q1M283", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M283#function" }, { "database": "UniProtKB", "id": "F1N4H8", "url": "https://www.uniprot.org/uniprotkb/F1N4H8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRLR", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40", "locus": { "chromosome": "20", "start_pos": 39117082, "end_pos": 39037656, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000025035", "url": "https://www.ensembl.org/id/ENSBTAG00000025035" } ] } } ], "crossref": [ { "id": "ENSBTAG00000025035", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000025035", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "281422", "url": "https://www.ncbi.nlm.nih.gov/gene/281422", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003528", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003528", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ANITCTW", "url": "https://omabrowser.org/oma/group/ANITCTW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M283", "url": "https://www.orthodb.org/?gene=A0A3Q1M283", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N4H8", "url": "https://www.orthodb.org/?gene=F1N4H8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23036:SF86", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23036:SF86", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1170546", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1170546", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-982772", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-982772", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005221632", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221632", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M283", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M283", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M283-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M283-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MJ05", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJ05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MJ05-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJ05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NV40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NV40-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4H8", "url": "https://www.uniprot.org/uniprotkb/F1N4H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4H8-1", "url": "https://www.uniprot.org/uniprotkb/F1N4H8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKENAASRVVFILLLFLSVSLLNGQSPPEKPKLVKCRSPGKETFTCWWEPGADGGLPTNYTLTYHKEGETLIHECPDYKTGGPNSCYFSKKHTSIWKMYVITVNAINQMGISSSDPLYVDVTYIVEPEPPANLTLELKHPEDRKPYLWIKWSPPTMTDVKSGWFIIQYEIRLKPEKATDWETHFTPKQTQLKIFNLYPGQKYLVQIRCKPDHGYWSEWSPESSIQIPNDFPVKDTSMWIFVAILSAVICLIMVWAVALKGYSMVTCILPPVPGPKIKGFDVHLLEKGKSEELLRALESQDFPPTSDCEDLLMEFIEVDDCEDQQLMPRPSKEHTEQGVKPMHLDLDSDSGRGSCDSPSLLSEKCDEPQAHPSKFHTPEGPEKLENPETNLTCLQAPQSTSGEGKIPYFLANGPKSSTWPFPQPPSLYSPRYSYHNIADVCELALGMAGTTATSLDQTDQHALKASKTIETGREGKATKQRESEGCSSKPDQDTVWPRPQDKTPLISAKPLEYVEIHKVSQDGVLALFPKQNEKFGAPEASKEYSKVSRVTDSNILVLVPDPQAQNLTLLEEPAKKAPPALP", "length": 581, "header": "tr|A0ABI0NV40-1|A0ABI0NV40_BOVIN Isoform 1 of Prolactin receptor OS=Bos taurus OX=9913 GN=PRLR PE=3 SV=1 CANONICAL=A0ABI0NV40-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M283-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40/entry#A0A3Q1M283-1", "sequence": { "sequence": "MKENAASRVVFILLLFLSVSLLNGQSPPEKPKLVKCRSPGKETFTCWWEPGADGGLPTNYTLTYHKEGETLIHECPDYKTGGPNSCYFSKKHTSIWKMYVITVNAINQMGISSSDPLYVDVTYIVEPEPPANLTLELKHPEDRKPYLWIKWSPPTMTDVKSGWFIIQYEIRLKPEKATDWETHFTPKQTQLKIFNLYPGQKYLVQIRCKPDHGYWSEWSPESSIQIPNDFPVKDTSMWIFVAILSAVICLIMVWAVALKGYSMVTCILPPVPGPKIKGFDVHLLEAAP", "length": 288, "header": "tr|A0A3Q1M283-1|A0ABI0NV40_BOVIN Computationally mapped isoform of Prolactin receptor OS=Bos taurus OX=9913 GN=PRLR PE=3 SV=2 CANONICAL=A0ABI0NV40-1" }, "locus": { "chromosome": "20", "start_pos": 39117082, "end_pos": 39077947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082398.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082398.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063878.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063878.2" } ] } }, { "isoform_ac": "A0A3Q1MJ05-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40/entry#A0A3Q1MJ05-1", "sequence": { "sequence": "GTENPASEVETGQSPPEKPKLVKCRSPGKETFTCWWEPGADGGLPTNYTLTYHKEGETLIHECPDYKTGGPNSCYFSKKHTSIWKMYVITVNAINQMGISSSDPLYVDVTYIVEPEPPANLTLELKHPEDRKPYLWIKWSPPTMTDVKSGWFIIQYEIRLKPEKATDWETHFTPKQTQLKIFNLYPGQKYLVQIRCKPDHGYWSEWSPESSIQIPNDFPVKDTSMWIFVAILSAVICLIMVWAVALKGYSMVTCILPPVPGPKIKGFDVHLLEKGKSEELLRALESQDFPPTSDCEDLLMEFIEVDDCEDQQLMPRPSKEHTEQGVKPMHLDLDSDSGRGSCDSPSLLSEKCDEPQAHPSKFHTPEGPEKLENPETNLTCLQAPQSTSGEGKIPYFLANGPKSSTWPFPQPPSLYSPRYSYHNIADVCELALGMAGTTATSLDQTDQHALKASKTIETGREGKATKQRESEGCSSKPDQDTVWPRPQDKTPLISAKPLEYVEIHKVSQDGVLALFPKQNEKFGAPEASKEYSKVSRVTDSNILVLVPDPQAQNLTLLEEPAKKAPPALP", "length": 569, "header": "tr|A0A3Q1MJ05-1|A0ABI0NV40_BOVIN Computationally mapped isoform of Prolactin receptor OS=Bos taurus OX=9913 GN=PRLR PE=3 SV=1 CANONICAL=A0ABI0NV40-1" }, "locus": { "chromosome": "20", "start_pos": 39099575, "end_pos": 39080028, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070880.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070880.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071300.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071300.2" } ] } }, { "isoform_ac": "A0ABI0NV40-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40/entry#A0ABI0NV40-1", "sequence": { "sequence": "MKENAASRVVFILLLFLSVSLLNGQSPPEKPKLVKCRSPGKETFTCWWEPGADGGLPTNYTLTYHKEGETLIHECPDYKTGGPNSCYFSKKHTSIWKMYVITVNAINQMGISSSDPLYVDVTYIVEPEPPANLTLELKHPEDRKPYLWIKWSPPTMTDVKSGWFIIQYEIRLKPEKATDWETHFTPKQTQLKIFNLYPGQKYLVQIRCKPDHGYWSEWSPESSIQIPNDFPVKDTSMWIFVAILSAVICLIMVWAVALKGYSMVTCILPPVPGPKIKGFDVHLLEKGKSEELLRALESQDFPPTSDCEDLLMEFIEVDDCEDQQLMPRPSKEHTEQGVKPMHLDLDSDSGRGSCDSPSLLSEKCDEPQAHPSKFHTPEGPEKLENPETNLTCLQAPQSTSGEGKIPYFLANGPKSSTWPFPQPPSLYSPRYSYHNIADVCELALGMAGTTATSLDQTDQHALKASKTIETGREGKATKQRESEGCSSKPDQDTVWPRPQDKTPLISAKPLEYVEIHKVSQDGVLALFPKQNEKFGAPEASKEYSKVSRVTDSNILVLVPDPQAQNLTLLEEPAKKAPPALP", "length": 581, "header": "tr|A0ABI0NV40-1|A0ABI0NV40_BOVIN Isoform 1 of Prolactin receptor OS=Bos taurus OX=9913 GN=PRLR PE=3 SV=1 CANONICAL=A0ABI0NV40-1" }, "locus": { "chromosome": "20", "start_pos": 39099575, "end_pos": 39077947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152713.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152713.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104494.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104494.1" } ] } }, { "isoform_ac": "F1N4H8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40/entry#F1N4H8-1", "sequence": { "sequence": "MKENAASRVVFILLLFLSVSLLNGQSPPEKPKLVKCRSPGKETFTCWWEPGADGGLPTNYTLTYHKEGETLIHECPDYKTGGPNSCYFSKKHTSIWKMYVITVNAINQMGISSSDPLYVDVTYIVEPEPPANLTLELKHPEDRKPYLWIKWSPPTMTDVKSGWFIIQYEIRLKPEKATDWETHFTPKQTQLKIFNLYPGQKYLVQIRCKPDHGYWSEWSPESSIQIPNDFPVKDTSMWIFVAILSAVICLIMVWAVALKGYSMVTCILPPVPGPKIKGFDVHLLEISQPSRLVSMF", "length": 296, "header": "tr|F1N4H8-1|A0ABI0NV40_BOVIN Computationally mapped isoform of Prolactin receptor OS=Bos taurus OX=9913 GN=PRLR PE=3 SV=4 CANONICAL=A0ABI0NV40-1" }, "locus": { "chromosome": "20", "start_pos": 39098681, "end_pos": 39077947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014437.6", "url": "https://www.ensembl.org/id/ENSBTAT00000014437.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014437.6", "url": "https://www.ensembl.org/id/ENSBTAP00000014437.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1170546", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1170546", "resource": "Reactome", "description": "Prolactin receptor signaling" }, { "id": "R-BTA-982772", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-982772", "resource": "Reactome", "description": "Growth hormone receptor signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QET6-1", "protein_name": "Prolactin receptor", "gene_name": "PRLR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKENVPSTVVFILLLFLNISLLNGQSPPGKPEIFKCRSPEKETFTCWWKPGADGGLPTNYTLTYHKEGETFTHECPDYKTGGPNSCYFNKKHTSIWTIYIITVNATNQMGSSSSDPRYVDVTYIVEPDPPVNLTLELKKPEDQKPYLWIKWLPPTLVDVRSGWLTLQYEIRLQPEKTAEWETHFAGQQTQFKILSLYPGQKYLVQVRCKPDHGFWSEWPESSIQIPNDFSMKDTTMWIFVAILSAVVCLIMIWAVALKGYSMVACILPPVPGPKIKGFDTHLLEKGKSEELLSALGCQDFPPTSDCEDLLVEFLEVDDSEDQQLMPAHSKEHPSQGRKPTHLDPDSDSGRGSCDSPSLLSEKCDEPRANPPKFHTPEGIEKPGDPETNLPRPQDPQSTSVESKLLYFHADGSKSSTWPLPQPPILHDPGSSYHNLADVGQLVLGTAGATAALLEKTDRHAFNPPKTTETGGEGRATEQKESESFHSKTDQGTVWLLPQDKGPFVSPKPMEYVEIHKVSKDGALALLPKQQENGDRPEKAGAPETSKEYAQVSRVMDNHILVLVQDPRARNVAPFEEPTKETPPSRPQNPAAKDLASFTTAPGHCRHPLGGLDYLDPAGFMHSFQ", "length": 624 }, "evidence": [ { "id": "A0ABI0NV40", "url": "https://omabrowser.org/oma/group/A0ABI0NV40/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YID9-1", "protein_name": "Prolactin receptor", "gene_name": "PRLR", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKQDLISSVQIILFLPLTTVGLAGQSFPGKPKIIRCRSLEKETFSCWWKPGSDGGLPTNYTLFYSKDSEEEIYECPDYRTSGPNSCYFNKNHTSPWTTFNITVTATNEIGSNSSDPQYVDVTSIVQPGSPVNLTLETKRSANIMYLWAKWSPPLLADANSNHLYHYELRIKPEEKEEWETISVGVQTQCKINRLNAGMRYVVQVRCTLDPGEWSEWSSERHILIPSGQSPPEKPTIIKCRSPEKETFTCWWKPGLDGGHPTNYTLLYSKEGEEQVYECPDYRTAGPNSCYFDKKHTSFWTIYNITVRATNEMGSNSSDPHYVDVTYIVQPDPPVNVTLELKKPINRKPYLVLTWSPPPLADVRSGWLTLEYELRLKPEEGEEWETIFVGQQTQYKMFSLNPGKKYIIQIHCKPDHHGSWSEWSSENYIQIPNDFRVKDMIVWIVLGVLSSLICLIMSWTMVLKGYRMITFILPPVPGPKIKGIDTHLLETGKSEELLSALGCHGFPPTSDCEELLIEYLEVEDSEDQQLMPSHDNGHPSKNAKITRKETDSDSGRGSCDSPSLLSEKCRETCALPSVLQTQEVRDVQEKKAAKRSWETQYVASERKALLSNSESAKSSTWPAVQLPNNQPPMFAYHSIVDAHKITLNTTNTNVAAVLVEDEEEHQSQCSLTETIPGEMEKQGEMENLHSKTEQTTAQVKQNRSNERLPFLDAALMDYVEVHKVIRQDEEPAVLLKHKENSGKIEKYTISGASKEYTKVSTVMDHNILVLMPDSRVPHTPASQEPAKETSQSLQQGQVEKNMSYCLTAPSDCKRETGGSEYMDPSSFMPSFK", "length": 831 }, "evidence": [ { "id": "A0ABI0NV40", "url": "https://omabrowser.org/oma/group/A0ABI0NV40/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7FHZ0-1", "protein_name": "Prolactin receptor", "gene_name": "Prlr", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKESMPSALAFILLFLNISLLNGQSPPGKPEIYKCRSPDKETFTCWWNPGTDGGLPTNYSLTYSKEGEKTTHECPDYETSGPNSCFFSKQYTSIWKIYVITVIATNQMGSSASDPLYVDVTYIVEPEPPRNLTLEVKQLKDKKTYLWIKWSPPTITDVKTGWFTMEYEIRLKSEEADEWEVHFTGQQTHFKVFDLYPGQKYIVQTRCKPDHGYWSRWGQENSIEIPNDFTLKNTTMWIIVAVLSAVICLIMVWAVALKGYSMMTCIFPPVPGPKIKGFDTHLLEKGKSEELLTALGCQDFPPTSDSEDLLVEFLEVDDNEDVQLMPSHSKEYPGQGVKPTHLDPDNDSGHGSYDSHSLLSEKCEEPQVYPPAFHIPEILEKPENPEANIPPTQDARSSTPYFHADVSKWSTWPLLPSQHMTRSPYHSIADVCKLAGGPVDTLASFLDKAGKNVLKFSKTLETEEEKVAEQEKKKSFHSETKQNTSWPLLQKNAPIVYAKPPDYVEIHKVNKDGVLSLFPKQKENDQVEKPGVPETSKEYTKVSGVMDDNILVLVPDSRAENTALFAESAKKVPPSLEQNQSAKDLASFAATSNNCRLQLGRLDYLDPTCFTHSFH", "length": 615 }, "evidence": [ { "id": "A0ABI0NV40", "url": "https://omabrowser.org/oma/group/A0ABI0NV40/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P05710-1", "protein_name": "Prolactin receptor", "gene_name": "Prlr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSALAFVLLVLNISLLKGQSPPGKPEIHKCRSPDKETFTCWWNPGTDGGLPTNYSLTYSKEGEKTTYECPDYKTSGPNSCFFSKQYTSIWKIYIITVNATNQMGSSSSDPLYVDVTYIVEPEPPRNLTLEVKQLKDKKTYLWVKWSPPTITDVKTGWFTMEYEIRLKPEEAEEWEIHFTGHQTQFKVFDLYPGQKYLVQTRCKPDHGYWSRWSQESSVEMPNDFTLKDTTVWIIVAILSAVICLIMVWAVALKGYSMMTCIFPPVPGPKIKGFDTHLLEKGKSEELLSALGCQDFPPTSDCEDLLVEFLEVDDNEDERLMPSHSKEYPGQGVKPTHLDPDSDSGHGSYDSHSLLSEKCEEPQAYPPTLHIPEITEKPENPEANIPPTVDPQSTNPNFHVDAPKSSTWPLLPGQHMPRSPYHSVADVCKLAGSPVNTLDSFLDKAEENVLKLSKALETGEEEVAEQKGAKSFPSDKQNTPWPLLQEKSPTVYVKPPDYVEIHKVNKDGVLSLFPKQRENNQTEKPGVPETSKEYAKVSGITDNNILVLVPDSRAQNTALLEESAKKAPPSFEADQSEKDLASFTATSSNRRLQLGRLDYLDPTCFMHSFH", "length": 610 }, "evidence": [ { "id": "A0ABI0NV40", "url": "https://omabrowser.org/oma/group/A0ABI0NV40/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P16471-1", "protein_name": "Prolactin receptor", "gene_name": "PRLR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKSEELLSALGCQDFPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTDSGRGSCDSPSLLSEKCEEPQANPSTFYDPEVIEKPENPETTHTWDPQCISMEGKIPYFHAGGSKCSTWPLPQPSQHNPRSSYHNITDVCELAVGPAGAPATLLNEAGKDALKSSQTIKSREEGKATQQREVESFHSETDQDTPWLLPQEKTPFGSAKPLDYVEIHKVNKDGALSLLPKQRENSGKPKKPGTPENNKEYAKVSGVMDNNILVLVPDPHAKNVACFEESAKEAPPSLEQNQAEKALANFTATSSKCRLQLGGLDYLDPACFTHSFH", "length": 622 }, "evidence": [ { "id": "A0ABI0NV40", "url": "https://omabrowser.org/oma/group/A0ABI0NV40/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q08501-1", "protein_name": "Prolactin receptor", "gene_name": "Prlr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSALAYMLLVLSISLLNGQSPPGKPEIHKCRSPDKETFTCWWNPGSDGGLPTNYSLTYSKEGEKNTYECPDYKTSGPNSCFFSKQYTSIWKIYIITVNATNEMGSSTSDPLYVDVTYIVEPEPPRNLTLEVKQLKDKKTYLWVKWLPPTITDVKTGWFTMEYEIRLKSEEADEWEIHFTGHQTQFKVFDLYPGQKYLVQTRCKPDHGYWSRWGQEKSIEIPNDFTLKDTTVWIIVAVLSAVICLIMVWAVALKGYSMMTCIFPPVPGPKIKGFDTHLLEKGKSEELLSALGCQDFPPTSDCEDLLVEFLEVDDNEDERLMPSHSKEYPGQGVKPTHLDPDSDSGHGSYDSHSLLSEKCEEPQAYPPAFHIPEITEKPENPEANIPPTPNPQNNTPNCHTDTSKSTTWPLPPGQHTRRSPYHSIADVCKLAGSPGDTLDSFLDKAEENVLKLSEDAGEEEVAVQEGAKSFPSDKQNTSWPPLQEKGPIVYAKPPDYVEIHKVNKDGVLSLLPKQRENHQTENPGVPETSKEYAKVSGVTDNNILVLVPDSRAQNTALLEESAKKVPPSLEQNQSEKDLASFTATSSNCRLQLGRLDYLDPTCFMHSFH", "length": 608 }, "evidence": [ { "id": "A0ABI0NV40", "url": "https://omabrowser.org/oma/group/A0ABI0NV40/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40" } ], "pmid": "" }, { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40" } ], "pmid": "" }, { "name": "cytokine binding", "id": "GO:0019955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019955", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40" } ], "pmid": "" }, { "name": "prolactin receptor activity", "id": "GO:0004925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004925", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40" } ], "pmid": "" }, { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NV40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV40" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 127, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 565, "end_pos": 567 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NXW8-1", "uniprot_ac": "A0ABI0NXW8", "uniprot_id": "A0ABI0NXW8_BOVIN", "mass": { "chemical_mass": 106807.0, "monoisotopic_mass": 106807.0 }, "refseq": { "ac": "XP_059745559", "name": "MORC family CW-type zinc finger protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745559" }, "gene_names": [ { "name": "MORC3", "type": "recommended", "evidence": [ { "id": "A0ABI0NXW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8" } ] }, { "name": "MORC3", "type": "synonym", "evidence": [ { "id": "XP_059745559", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745559" } ] } ], "protein_names": [ { "name": "MORC family CW-type zinc finger 3", "type": "synonym", "evidence": [ { "id": "A0ABI0NXW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8/entry#names_and_taxonomy" } ] }, { "name": "MORC family CW-type zinc finger protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059745559", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745559" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXW8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MORC3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8", "locus": { "chromosome": "1", "start_pos": 148647083, "end_pos": 148604900, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011876", "url": "https://www.ensembl.org/id/ENSBTAG00000011876" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011876", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011876", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16931", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16931", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "513807", "url": "https://www.ncbi.nlm.nih.gov/gene/513807", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MFY1", "url": "https://www.orthodb.org/?gene=F1MFY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23336:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23336:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07496", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07496", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13589", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13589", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17942", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17942", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059745559", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745559", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NXW8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXW8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MFY1", "url": "https://www.uniprot.org/uniprotkb/F1MFY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MFY1-1", "url": "https://www.uniprot.org/uniprotkb/F1MFY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATQPPSGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDCICLTFTDNGNGMTSDKLHKMLSFGFSEKVTMNDHVPVGLYGNGFKSGSMRLGKDAMVFTKNEESMSVGFLSQTYLEVIKAEHVVVPIVSFNKQRQVLDSTESKASLAAILEHSLFSKEQQLLAELDAIIGKKGTRIIIWNLRSYKSATEFDFDKDKYDIRIPEDLDETAGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDIYRPKFLTNKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIDCYFLKPTHNKQDFDYTNEYRLTITALGDKLNDYWNEMKVKKHAEYPLNLPVEDIQKRPDQTWVQCDSCLKWRKLPDGIDQLPEKWYCSNNPDPQFRNCDVPEEPEDEDVVHPTYEKTYKKKDREKFRIRQLETAPRIHAELLFPKTPVSSQTFTPVKEGVPRGHLSEVANTYSTRLINHHRGSPQSEPENNSLKRRLPTRSSILNAKNRRLSNQVFENSHQDDDDDEDVIILEENSTPKPAGDDDTEVKLQQSPMEQSGVEVEPVGDSEPCGQTGSTGTSTSQCDQGTTTATQTEVPSLVVKKEETVEDAIDVRNDTAALPACVETEGKTHETQGTFDKSASDASCKLNELRNELLLVTQEKENYKRQCHMFTEQINVLQQRILEMNNKYVKKETCHQSTETDAVFLLESINGKPESPDHVVSQYRQALEEIERLKKQCSALQHVKAECSQCSSSESKSEVDEMVVQLDDVFRQLDKCSVERDQYKSEIELLEVEKSQIRSQCEELKAEIEQLKSASGQVGADVSTSSNIEESVNYTDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST", "length": 940, "header": "tr|A0ABI0NXW8-1|A0ABI0NXW8_BOVIN Isoform 1 of MORC family CW-type zinc finger 3 OS=Bos taurus OX=9913 GN=MORC3 PE=4 SV=1 CANONICAL=A0ABI0NXW8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NXW8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8/entry#A0ABI0NXW8-1", "sequence": { "sequence": "MATQPPSGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDCICLTFTDNGNGMTSDKLHKMLSFGFSEKVTMNDHVPVGLYGNGFKSGSMRLGKDAMVFTKNEESMSVGFLSQTYLEVIKAEHVVVPIVSFNKQRQVLDSTESKASLAAILEHSLFSKEQQLLAELDAIIGKKGTRIIIWNLRSYKSATEFDFDKDKYDIRIPEDLDETAGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDIYRPKFLTNKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIDCYFLKPTHNKQDFDYTNEYRLTITALGDKLNDYWNEMKVKKHAEYPLNLPVEDIQKRPDQTWVQCDSCLKWRKLPDGIDQLPEKWYCSNNPDPQFRNCDVPEEPEDEDVVHPTYEKTYKKKDREKFRIRQLETAPRIHAELLFPKTPVSSQTFTPVKEGVPRGHLSEVANTYSTRLINHHRGSPQSEPENNSLKRRLPTRSSILNAKNRRLSNQVFENSHQDDDDDEDVIILEENSTPKPAGDDDTEVKLQQSPMEQSGVEVEPVGDSEPCGQTGSTGTSTSQCDQGTTTATQTEVPSLVVKKEETVEDAIDVRNDTAALPACVETEGKTHETQGTFDKSASDASCKLNELRNELLLVTQEKENYKRQCHMFTEQINVLQQRILEMNNKYVKKETCHQSTETDAVFLLESINGKPESPDHVVSQYRQALEEIERLKKQCSALQHVKAECSQCSSSESKSEVDEMVVQLDDVFRQLDKCSVERDQYKSEIELLEVEKSQIRSQCEELKAEIEQLKSASGQVGADVSTSSNIEESVNYTDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST", "length": 940, "header": "tr|A0ABI0NXW8-1|A0ABI0NXW8_BOVIN Isoform 1 of MORC family CW-type zinc finger 3 OS=Bos taurus OX=9913 GN=MORC3 PE=4 SV=1 CANONICAL=A0ABI0NXW8-1" }, "locus": { "chromosome": "1", "start_pos": 148646079, "end_pos": 148604914, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154656.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154656.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106133.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106133.1" } ] } }, { "isoform_ac": "F1MFY1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8/entry#F1MFY1-1", "sequence": { "sequence": "MATQPPSGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDCICLTFTDNGNGMTSDKLHKMLSFGFSEKVTMNDHVPVGLYGNGFKSGSMRLGKDAMVFTKNEESMSVGFLSQTYLEVIKAEHVVVPIVSFNKQRQVLDSTESKASLAAILEHSLFSKEQQLLAELDAIIGKKGTRIIIWNLRSYKSATEFDFDKDKYDIRIPEDLDETAGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDIYRPKFLLKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIDCYFLKPTHNKQDFDYTNEYRLTITALGDKLNDYWNEMKVKKHAEYPLNLPVEDIQKRPDQTWVQCDSCLKWRKLPDGIDQLPEKWYCSNNPDPQFRNCDVPEEPEDEDVVHPTYEKTYKKKDREKFRIRQLETAPRIHAELLFPKTPVSSQTFTPVKEGVPRGHLSEVANTYSTRLINHHRGSPQSEPENNSLKRRLPTRSSILNAKNRRLSNQVFENSHQDDDDDEDVIILEENSTPKPAGDDDTEVKLQQSPMEQSGVEVEPVGDSEPCGQTGSTGTSTSQCDQGTTTATQTEVPSLVVKKEETVEDAIDVRNDTAALPACVETEGKTHETQGTFDKSASDASCKLNELRNELLLVTQEKENYKRQCHMFTEQINVLQQRILEMNNKYVKKETCHQSTETDAVFLLESINGKPESPDHVVSQYRQALEEIERLKKQCSALQHVKAECSQCSSSESKSEVDEMVVQLDDVFRQLDKCSVERDQYKSEIELLEVEKSQIRSQCEELKAEIEQLKSASGQVGADVSTSSNIEESVNYTDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST", "length": 939, "header": "tr|F1MFY1-1|A0ABI0NXW8_BOVIN Computationally mapped isoform of MORC family CW-type zinc finger 3 OS=Bos taurus OX=9913 GN=MORC3 PE=4 SV=3 CANONICAL=A0ABI0NXW8-1" }, "locus": { "chromosome": "1", "start_pos": 148646079, "end_pos": 148604914, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015758.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015758.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015758.6", "url": "https://www.ensembl.org/id/ENSBTAP00000015758.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXW8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXW8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXW8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXW8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8" } ], "pmid": "" }, { "name": "histone H3K4me3 reader activity", "id": "GO:0140002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140002", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXW8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXW8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 664, "end_pos": 666, "annotation": "n_glycosylation_sequon" }, { "start_pos": 884, "end_pos": 886, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NXW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW8" }, { "id": "PS51050", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51050" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CW-type", "eco_id": "ECO_0000259", "start_pos": 405, "end_pos": 455, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 22, "end_pos": 24 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 539, "end_pos": 541 }, { "start_pos": 584, "end_pos": 586 }, { "start_pos": 664, "end_pos": 666 }, { "start_pos": 884, "end_pos": 886 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NZK3-1", "uniprot_ac": "A0ABI0NZK3", "uniprot_id": "A0ABI0NZK3_BOVIN", "mass": { "chemical_mass": 51087.0, "monoisotopic_mass": 51087.0 }, "refseq": { "ac": "XP_002693085", "name": "tryptophan 5-hydroxylase 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693085" }, "gene_names": [ { "name": "TPH1", "type": "recommended", "evidence": [ { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ] }, { "name": "TPH1", "type": "synonym", "evidence": [ { "id": "XP_002693085", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693085" } ] } ], "protein_names": [ { "name": "tryptophan 5-monooxygenase", "type": "recommended", "evidence": [ { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3/entry#names_and_taxonomy" } ] }, { "name": "1.14.16.4", "type": "synonym", "evidence": [ { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3/entry#names_and_taxonomy" } ] }, { "name": "tryptophan 5-hydroxylase 1", "type": "synonym", "evidence": [ { "id": "XP_002693085", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693085" } ] } ], "function": [ { "annotation": "Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis.", "evidence": [ { "database": "UniProtKB", "id": "F1N5Q8", "url": "https://www.uniprot.org/uniprotkb/F1N5Q8#function" }, { "database": "UniProtKB", "id": "ARBA00037406", "url": "https://www.uniprot.org/uniprotkb/ARBA00037406#function" }, { "database": "UniProtKB", "id": "A0ABI0NZK3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZK3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TPH1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3", "locus": { "chromosome": "15", "start_pos": 34474487, "end_pos": 34443795, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005343", "url": "https://www.ensembl.org/id/ENSBTAG00000005343" } ] } } ], "crossref": [ { "id": "ENSBTAG00000005343", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005343", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03346", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03346", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04929", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04929", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "781941", "url": "https://www.ncbi.nlm.nih.gov/gene/781941", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036951", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036951", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:781941", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781941", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DMPWFPR", "url": "https://omabrowser.org/oma/group/DMPWFPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N5Q8", "url": "https://www.orthodb.org/?gene=F1N5Q8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11473", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11473", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11473:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11473:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00351", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00351", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-209931", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-209931", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002693085", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693085", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16709", "url": "https://www.rhea-db.org/rhea/16709", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NZK3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZK3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5Q8", "url": "https://www.uniprot.org/uniprotkb/F1N5Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5Q8-1", "url": "https://www.uniprot.org/uniprotkb/F1N5Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIEDNKENKDHSFERGRATLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRSSEFEIFVDCDISREQLNDIFHLLKSHSNILSVNLPDNFTVKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPRVEFTEEEIRTWGTVFRELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCKQEGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTRSITSAMNELQHELDVVSDALAKVSRQLSI", "length": 444, "header": "tr|A0ABI0NZK3-1|A0ABI0NZK3_BOVIN Isoform 1 of tryptophan 5-monooxygenase OS=Bos taurus OX=9913 GN=TPH1 PE=3 SV=1 CANONICAL=A0ABI0NZK3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NZK3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3/entry#A0ABI0NZK3-1", "sequence": { "sequence": "MIEDNKENKDHSFERGRATLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRSSEFEIFVDCDISREQLNDIFHLLKSHSNILSVNLPDNFTVKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPRVEFTEEEIRTWGTVFRELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCKQEGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTRSITSAMNELQHELDVVSDALAKVSRQLSI", "length": 444, "header": "tr|A0ABI0NZK3-1|A0ABI0NZK3_BOVIN Isoform 1 of tryptophan 5-monooxygenase OS=Bos taurus OX=9913 GN=TPH1 PE=3 SV=1 CANONICAL=A0ABI0NZK3-1" }, "locus": { "chromosome": "15", "start_pos": 34473483, "end_pos": 34453157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152382.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152382.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105690.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105690.1" } ] } }, { "isoform_ac": "F1N5Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3/entry#F1N5Q8-1", "sequence": { "sequence": "MSDTFEESHSRPSMTTVNKWSFYFHTLFLEKYTKLIMIEDNKENKDHSFERGRATLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRSSEFEIFVDCDISREQLNDIFHLLKSHSNILSVNLPDNFTVKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPRVEFTEEEIRTWGTVFRELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCKQEGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTRSITSAMNELQHELDVVSDALAKVSRQLSI", "length": 480, "header": "tr|F1N5Q8-1|A0ABI0NZK3_BOVIN Computationally mapped isoform of tryptophan 5-monooxygenase OS=Bos taurus OX=9913 GN=TPH1 PE=3 SV=3 CANONICAL=A0ABI0NZK3-1" }, "locus": { "chromosome": "15", "start_pos": 34473483, "end_pos": 34451842, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007030.7", "url": "https://www.ensembl.org/id/ENSBTAT00000007030.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007030.5", "url": "https://www.ensembl.org/id/ENSBTAP00000007030.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:781941", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781941", "resource": "KEGG Pathway" }, { "id": "R-BTA-209931", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-209931", "resource": "Reactome", "description": "Serotonin and melatonin biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A964-1", "protein_name": "tryptophan 5-monooxygenase", "gene_name": "TPH1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEGLSCVWKDATAQLSPYLFYLCPMESSSPQEERRCGTDSLYWSASQTAKKEKSLHCQGEGLELSKSNYMMIEDNKENKDHAPERGRTAIIFSLKNEVGGLVKALKLFQEKHVNLVHIESRKSKRRNSEFEIFVDCDSNREQLNEIFQLLKSHVSIVSMNPTEHFNVQEDGDMENIPWYPKKISDLDKCANRVLMYGSDLDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPEIEFTEEEIKTWGTVYRELNKLYPTHACREYLKNLPLLTKYCGYREDNIPQLEDVSRFLKERTGFTIRPVAGYLSPRDFLAGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASDEAVQKLATCYFFTVEFGLCKQEGQLRVYGAGLLSSISELKHSLSGSAKVKPFDPKVTCKQECLITTFQEVYFVSESFEEAKEKMREFAKTIKRPFGVKYNPYTQSVQILKDTKSIASVVNELRHELDIVSDALSKMGKQLEV", "length": 515 }, "evidence": [ { "id": "A0ABI0NZK3", "url": "https://omabrowser.org/oma/group/A0ABI0NZK3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P09810-1", "protein_name": "Tryptophan 5-hydroxylase 1", "gene_name": "Tph1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIEDNKENKDHSSERGRVTLIFSLKNEVGGLIKALKIFQENHVNLLHIESRKSKRRNSEFEIFVDCDINREQLNDIFPLLKSHTTVLSVDSPDQLPEKEDVMETVPWFPKKISDLDFCANRVLLYGSELDADHPGFKDNVYRRRRKYFAELAMNYKHGDPIPKIEFTEEEIKTWGTIFRELNKLYPTHACREYLRNLPLLSKYCGYREDNVPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEETVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELRHALSGHAKVKPFDPKVACKQECLITSFQDVYFVSESFEDAKEKMREFAKTVKRPFGVKYNPYTQSIQVLRDSKSITSAMNELRHDLDVVNDALARVSRWPSV", "length": 444 }, "evidence": [ { "id": "A0ABI0NZK3", "url": "https://omabrowser.org/oma/group/A0ABI0NZK3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P17532-1", "protein_name": "Tryptophan 5-hydroxylase 1", "gene_name": "Tph1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIEDNKENKENKDHSSERGRVTLIFSLENEVGGLIKVLKIFQENHVSLLHIESRKSKQRNSEFEIFVDCDISREQLNDIFPLLKSHATVLSVDSPDQLTAKEDVMETVPWFPKKISDLDFCANRVLLYGSELDADHPGFKDNVYRRRRKYFAELAMNYKHGDPIPKIEFTEEEIKTWGTIFRELNKLYPTHACREYLRNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEETVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKIACKQECLITSFQDVYFVSESFEDAKEKMREFAKTVKRPFGLKYNPYTQSVQVLRDTKSITSAMNELRYDLDVISDALARVTRWPSV", "length": 447 }, "evidence": [ { "id": "A0ABI0NZK3", "url": "https://omabrowser.org/oma/group/A0ABI0NZK3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P17752-1", "protein_name": "Tryptophan 5-hydroxylase 1", "gene_name": "TPH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIEDNKENKDHSLERGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEFEIFVDCDINREQLNDIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDALAKVSRKPSI", "length": 444 }, "evidence": [ { "id": "A0ABI0NZK3", "url": "https://omabrowser.org/oma/group/A0ABI0NZK3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70080-1", "protein_name": "Tryptophan 5-hydroxylase 1", "gene_name": "TPH1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIEDNKENKDHAPERGRTAIIFSLKNEVGGLVKALKLFQEKHVNLVHIESRKSKRRNSEFEIFVDCDSNREQLNEIFQLLKSHVSIVSMNPTEHFNVQEDGDMENIPWYPKKISDLDKCANRVLMYGSDLDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPEIEFTEEEIKTWGTVYRELNKLYPTHACREYLKNLPLLTKYCGYREDNIPQLEDVSRFLKERTGFTIRPVAGYLSPRDFLAGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASDEAVQKLATCYFFTVEFGLCKQEGQLRVYGAGLLSSISELKHSLSGSAKVKPFDPKVTCKQECLITTFQEVYFVSESFEEAKEKMREFAKTIKRPFGVKYNPYTQSVQILKDTKSIASVVNELRHELDIVSDALSKMGKQLEV", "length": 445 }, "evidence": [ { "id": "A0ABI0NZK3", "url": "https://omabrowser.org/oma/group/A0ABI0NZK3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9W0K2-1", "protein_name": "Tryptophan 5-hydroxylase 2", "gene_name": "Trhn", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSASGKSLLGLWLYRSGEQEWAVKQGSPLHQLKKDSTTSGSSSHPSLGRNASAPPEPPRLAIGGGGQDNGRQHSPGERISIIFTLRNQVGNLARALQVFQELGINVLHLELSPLEMATNQADVLVDVECDQRRLDQVVKMLNREVASVNYTSVNTQGLARAPSLSACSSFDFGDMVWFPRKISDLDKAQNVLMYGSELDADHPGFKDPVYRKRREQFSAIANNFKHGNPIPRVQYTPEEVKTWGTVFLELHRLYVLHAVPEYMDNWPELEKYCGYREDNVPQLQDVSVYLKRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQYIRHSSDPFYTPEPDCCHELLGHMPLLANSSFAQFSQEIGLASLGASDADIEKLATLYFFTVEFGLCKQADSTFKVYGAGLLSSVAELQHAITAENKIKKFDPEVTCQQECIITSYQNAYYYTDSFEEAKEQMRAFAESIQRPFGVRYNPYTMSVEVLSNAKKITAVVSELRGDLSIVCSALRKISATDENLDVDSIANMLHNSLNVRGGASGGGGSPCSPDNSDNSTAEGD", "length": 555 }, "evidence": [ { "id": "A0ABI0NZK3", "url": "https://omabrowser.org/oma/group/A0ABI0NZK3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "tryptophan 5-monooxygenase activity", "id": "GO:0004510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004510", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZK3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZK3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "platelet degranulation", "id": "GO:0002576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002576", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZK3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ], "pmid": "" }, { "name": "serotonin biosynthetic process from tryptophan", "id": "GO:0006587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006587", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZK3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ], "pmid": "" }, { "name": "regulation of hemostasis", "id": "GO:1900046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900046", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZK3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ], "pmid": "" }, { "name": "serotonin biosynthetic process", "id": "GO:0042427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042427", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZK3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ], "pmid": "" }, { "name": "aromatic amino acid metabolic process", "id": "GO:0009072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009072", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZK3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZK3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZK3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16709", "name": "", "equation": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BGX6-1", "A0ABI0NZK3-1" ], "evidence": [ { "id": "16709", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16709" } ] }, { "id": "R-BTA-209828", "name": "Tryptophan is hydroxylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NZK3-1", "E1BGX6-1" ], "evidence": [ { "id": "R-BTA-209828", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-209828" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0ABI0NZK3", "gene_name": "TPH1", "activity": [ { "ec_number": "1.14.16.4", "activity": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin.", "evidence": [ { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ] }, { "ec_number": "1.14.16.4", "activity": "", "evidence": [ { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" } ] } ] }, { "uniprot_ac": "E1BGX6", "gene_name": "TPH2", "activity": [ { "ec_number": "1.14.16.4", "activity": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin.", "evidence": [ { "id": "E1BGX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX6" } ] }, { "ec_number": "1.14.16.4", "activity": "", "evidence": [ { "id": "E1BGX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGX6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" }, { "id": "PS51671", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51671" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ACT", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 94, "start_aa": "Thr", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" }, { "id": "PS51410", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51410" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Biopterin-dependent aromatic amino acid hydroxylase family profile", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 439, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3#function" }, { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" }, { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" } ], "binding_site_uniprot": 272, "amino_acid": "His", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 272, "end_pos": 272, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3#function" }, { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" }, { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" } ], "binding_site_uniprot": 277, "amino_acid": "His", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 277, "end_pos": 277, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1N5Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5Q8#function" }, { "id": "F1N5Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5Q8" }, { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" } ], "binding_site_uniprot": 308, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 308, "end_pos": 308, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1N5Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5Q8#function" }, { "id": "F1N5Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5Q8" }, { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" } ], "binding_site_uniprot": 313, "amino_acid": "Phe", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 313, "end_pos": 313, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3#function" }, { "id": "A0ABI0NZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZK3" }, { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" } ], "binding_site_uniprot": 317, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 317, "end_pos": 317, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1N5Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5Q8#function" }, { "id": "F1N5Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5Q8" }, { "id": "PIRSR000336-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR000336-1" } ], "binding_site_uniprot": 353, "amino_acid": "Pro", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 353, "end_pos": 353, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.16.4", "ec_name": "(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2 = 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin.", "evidence": [ { "id": "1.14.16.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.16.4" }, { "id": "1.14.16.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.16.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NUK1-1", "uniprot_ac": "A0ABI0NUK1", "uniprot_id": "A0ABI0NUK1_BOVIN", "mass": { "chemical_mass": 109411.0, "monoisotopic_mass": 109411.0 }, "refseq": { "ac": "NP_001179331", "name": "catenin delta-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179331" }, "gene_names": [ { "name": "CTNND1", "type": "recommended", "evidence": [ { "id": "A0ABI0NUK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1" } ] }, { "name": "CTNND1", "type": "synonym", "evidence": [ { "id": "NP_001179331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179331" } ] } ], "protein_names": [ { "name": "Catenin delta 1", "type": "synonym", "evidence": [ { "id": "A0ABI0NUK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1/entry#names_and_taxonomy" } ] }, { "name": "catenin (cadherin-associated protein), delta 1", "type": "synonym", "evidence": [ { "id": "NP_001179331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179331" } ] }, { "name": "catenin delta-1", "type": "synonym", "evidence": [ { "id": "NP_001179331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179331" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUK1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CTNND1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1", "locus": { "chromosome": 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"https://www.ebi.ac.uk/interpro/entry/IPR028435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515187", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515187", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LLH4", "url": "https://www.orthodb.org/?gene=A0A3Q1LLH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LZ84", "url": "https://www.orthodb.org/?gene=A0A3Q1LZ84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M7R4", "url": "https://www.orthodb.org/?gene=A0A3Q1M7R4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQ11", "url": "https://www.orthodb.org/?gene=E1BQ11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10372", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10372:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10372:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00514", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00514", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-418990", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418990", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5218920", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5218920", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9762292", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9762292", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9764561", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9764561", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9766229", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9766229", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9958810", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958810", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9958825", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179331", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179331", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLH4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZ84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZ84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZ84-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZ84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1Q5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7R4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUK1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUK1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6V4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6V4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6V4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6V4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQ11", "url": "https://www.uniprot.org/uniprotkb/E1BQ11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQ11-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDSEVESPASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDASPLLANGTLTRRHQNGRFVGDADLERQKFSDLSLNGPQDHSHLLYSTVPRMQEPGQIVETYTEEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVPMGPDGLPVDASAVSNSYIQTLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGSGDNYGSLSRVTRIEERYRPSMEGYRAPSRQDVYGPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSMGYDDVDYGMMSDYGTGRRTGTPSDPRRRLRSYEDMIGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGVPVLVGLLDHPKKEVHLGACGALKNISFGRDQENKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPSEDCKPRHVEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAPPSVANSTGPHAASCFGAKKGKGKKPTEDPTNDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKNPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQSSSQNFSEDTVVSILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVSLNNASRSQSSHSYDDSTLPLIDRSQRSDKKPDREEIQMSSMGSNTKSLDNNYSTLNERGDHNRTLDRPGDLGEMEPLKGAPLMQDEGQESLEEELDVLFWMRGSPCLALPCRRFSTTLSATSGLIIYVLLFFGGEMD", "length": 983, "header": "tr|A0ABI0NUK1-1|A0ABI0NUK1_BOVIN Isoform 1 of Catenin delta 1 OS=Bos taurus OX=9913 GN=CTNND1 PE=1 SV=1 CANONICAL=A0ABI0NUK1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLH4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1/entry#A0A3Q1LLH4-1", "sequence": { "sequence": "MDDSEVESPASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDASPLLANGTLTRRHQDHSHLLYSTVPRMQEPGQIVETYTEEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVPMGPDGLPVDASAVSNSYIQTLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGSGDNYGSLSRVTRIEERYRPSMEGYRAPSRQDVYGPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSMGYDDVDYGMMSDYGTGRRTGTPSDPRRRLRSYEDMIGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGVPVLVGLLDHPKKEVHLGACGALKNISFGRDQENKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPSEDCKPRHVEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAPPSVANSTGPHAASCFGAKKGKDEWFSRGKKPTEDPTNDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKNPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQSSSQNFSEDTVVSILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVSLNNASRSQSSHSYDDSTLPLIDRSQRSDKKPDREEIQMSSMGSNTKSLDNNYSTLNERGDHNRTLDRPGDLGEMEPLKGAPLMQKI", "length": 914, "header": "tr|A0A3Q1LLH4-1|A0ABI0NUK1_BOVIN Computationally mapped isoform of Catenin delta 1 OS=Bos taurus OX=9913 GN=CTNND1 PE=1 SV=2 CANONICAL=A0ABI0NUK1-1" }, "locus": { "chromosome": "15", "start_pos": 81010218, "end_pos": 80991780, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079341.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079341.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057419.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057419.2" } ] } }, { "isoform_ac": "A0A3Q1LZ84-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1/entry#A0A3Q1LZ84-1", "sequence": { "sequence": "MDDSEVESPASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDASPLLANGTLTRRHQNGRFVGDADLERQKFSDLSLNGPQDHSHLLYSTVPRMQEPGQIVETYTEEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVPMGPDGLPVDASAVSNSYIQTLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGSGDNYGSLSRVTRIEERYRPSMEGYRAPSRQDVYGPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSMGYDDVDYGMMSDYGTGRRTGTPSDPRRRLRSYEDMIGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKENKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPSEDCKPRHVEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAPPSVANSTGPHAASCFGAKKGKGKKPTEDPTNDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKNPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQSSSQNFSEDTVVSILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVSLNNASRSQSSHSYDDSTLPLIDRSQRSDKKPDREEIQMSSMGSNTKSLDNNYSTLNERGDHNRTLDRPGDLGEMEPLKGAPLMVNP", "length": 890, "header": "tr|A0A3Q1LZ84-1|A0ABI0NUK1_BOVIN Computationally mapped isoform of Catenin delta 1 OS=Bos taurus OX=9913 GN=CTNND1 PE=1 SV=2 CANONICAL=A0ABI0NUK1-1" }, "locus": { "chromosome": "15", "start_pos": 81009449, "end_pos": 80991780, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075996.3", "url": "https://www.ensembl.org/id/ENSBTAT00000075996.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061005.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061005.2" } ] } }, { "isoform_ac": "A0A3Q1M1Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1/entry#A0A3Q1M1Q5-1", "sequence": { "sequence": "MDDSEVESPASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDASPLLANGTLTRRHQNGRFVGDADLERQKFSDLSLNGPQDHSHLLYSTVPRMQEPGQIVETYTEEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVPMGPDGLPVDASAVSNSYIQTLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGSGDNYGSLSRVTRIEERYRPSMEGYRAPSRQDVYGPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSMGYDDVDYGMMSDYGTGRRTGTPSDPRRRLRSYEDMIGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGVPVLVGLLDHPKKEVHLGACGALKNISFGRDQENKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPSEDCKPRHVEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAPPSVANSTGPHAASCFGAKKGKDEWFSRGKKPTEDPTNDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKNPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQSSSQNFSEDTVVSILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVSLNNASRSQSSHSYDDSTLPLIDRSQRSDKKPDREEIQMSSMGSNTKSLDNNYSTLNERGDHNRTLDRPGDLGEMEPLKGAPLMQKI", "length": 938, "header": "tr|A0A3Q1M1Q5-1|A0ABI0NUK1_BOVIN Computationally mapped isoform of Catenin delta 1 OS=Bos taurus OX=9913 GN=CTNND1 PE=1 SV=1 CANONICAL=A0ABI0NUK1-1" }, "locus": { "chromosome": "15", "start_pos": 81010218, "end_pos": 80991780, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072638.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072638.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063886.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063886.2" } ] } }, { "isoform_ac": "A0A3Q1M7R4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1/entry#A0A3Q1M7R4-1", "sequence": { "sequence": "MDDSEVESPASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDASPLLANGTLTRRHQNGRFVGDADLERQKFSDLSLNGPQDHSHLLYSTVPRMQEPGQIVETYTEEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVPMGPDGLPVDASAVSNSYIQTLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGSGDNYGSLSRVTRIEERYRPSMEGYRAPSRQDVYGPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSMGYDDVDYGMMSDYGTGRRTGTPSDPRRRLRSYEDMIGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGVPVLVGLLDHPKKEVHLGACGALKNISFGRDQENKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPSEDCKPRHVEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAPPSVANSTGPHAASCFGAKKGKDEWFSRGKKPTEDPTNDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKNPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQSSSQNFSEDTVVSILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVSLNNASRSQSSHSYDDSTLPLIDRSQRSDNNYSTLNERGDHNRTLDRPGDLGEMEPLKGAPLMQKI", "length": 917, "header": "tr|A0A3Q1M7R4-1|A0ABI0NUK1_BOVIN Computationally mapped isoform of Catenin delta 1 OS=Bos taurus OX=9913 GN=CTNND1 PE=1 SV=2 CANONICAL=A0ABI0NUK1-1" }, "locus": { "chromosome": "15", "start_pos": 81010218, "end_pos": 80991780, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067241.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067241.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069896.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069896.2" } ] } }, { "isoform_ac": "A0ABI0NUK1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1/entry#A0ABI0NUK1-1", "sequence": { "sequence": "MDDSEVESPASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDASPLLANGTLTRRHQNGRFVGDADLERQKFSDLSLNGPQDHSHLLYSTVPRMQEPGQIVETYTEEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVPMGPDGLPVDASAVSNSYIQTLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGSGDNYGSLSRVTRIEERYRPSMEGYRAPSRQDVYGPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSMGYDDVDYGMMSDYGTGRRTGTPSDPRRRLRSYEDMIGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGVPVLVGLLDHPKKEVHLGACGALKNISFGRDQENKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPSEDCKPRHVEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAPPSVANSTGPHAASCFGAKKGKGKKPTEDPTNDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKNPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQSSSQNFSEDTVVSILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVSLNNASRSQSSHSYDDSTLPLIDRSQRSDKKPDREEIQMSSMGSNTKSLDNNYSTLNERGDHNRTLDRPGDLGEMEPLKGAPLMQDEGQESLEEELDVLFWMRGSPCLALPCRRFSTTLSATSGLIIYVLLFFGGEMD", "length": 983, "header": "tr|A0ABI0NUK1-1|A0ABI0NUK1_BOVIN Isoform 1 of Catenin delta 1 OS=Bos taurus OX=9913 GN=CTNND1 PE=1 SV=1 CANONICAL=A0ABI0NUK1-1" }, "locus": { "chromosome": "15", "start_pos": 81010288, "end_pos": 80991780, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151274.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151274.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104148.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104148.1" } ] } }, { "isoform_ac": "A0ABI0P6V4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1/entry#A0ABI0P6V4-1", "sequence": { "sequence": "MDDSEVESPASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDASPLLANGTLTRRHQNGRFVGDADLERQKFSDLSLNGPQDHSHLLYSTVPRMQEPGQIVETYTEEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVPMGPDGLPVDASAVSNSYIQTLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGSGDNYGSLSRVTRIEERYRPSMEGYRAPSRQDPYGLEDDQRSMGYDDVDYGMMSDYGTGRRTGTPSDPRRRLRSYEDMIGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGVPVLVGLLDHPKKEVHLGACGALKNISFGRDQENKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPSEDCKPRHVEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAPPSVANSTGPHAASCFGAKKGKGKKPTEDPTNDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKNPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQSSSQNFSEDTVVSILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVSLNNASRSQSSHSYDDSTLPLIDRSQRSDKKPDREEIQMSSMGSNTKSLDNNYSTLNERGDHNRTLDRPGDLGEMEPLKGAPLMQKI", "length": 909, "header": "tr|A0ABI0P6V4-1|A0ABI0P6V4_BOVIN Computationally mapped isoform of Catenin delta 1 OS=Bos taurus OX=9913 GN=CTNND1 PE=1 SV=1 CANONICAL=A0ABI0NUK1-1" }, "locus": { "chromosome": "15", "start_pos": 81010218, "end_pos": 80991780, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142962.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142962.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106795.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106795.1" } ] } }, { "isoform_ac": "E1BQ11-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1/entry#E1BQ11-1", "sequence": { "sequence": "MDDSEVESPASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDASPLLANGTLTRRHQNGRFVGDADLERQKFSDLSLNGPQDHSHLLYSTVPRMQEPGQIVETYTEEDPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVPMGPDGLPVDASAVSNSYIQTLGRDFRKNGNGGPGPYVGQAGTATLPRNFHYPPDGYSRHYEDGYPGSGDNYGSLSRVTRIEERYRPSMEGYRAPSRQDVYGPQPQVRVGGSSVDLHRFHPEPYGLEDDQRSMGYDDVDYGMMSDYGTGRRTGTPSDPRRRLRSYEDMIGEEVPSDQYYWAPLAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGVPVLVGLLDHPKKEVHLGACGALKNISFGRDQENKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPSEDCKPRHVEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAPPSVANSTGPHAASCFGAKKGKGKKPTEDPTNDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKNPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQSSSQNFSEDTVVSILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVSLNNASRSQSSHSYDDSTLPLIDRSQRSDKKPDREEIQMSSMGSNTKSLDNNYSTLNERGDHNRTLDRPGDLGEMEPLKGAPLMQKI", "length": 932, "header": "tr|E1BQ11-1|A0ABI0NUK1_BOVIN Computationally mapped isoform of Catenin delta 1 OS=Bos taurus OX=9913 GN=CTNND1 PE=1 SV=5 CANONICAL=A0ABI0NUK1-1" }, "locus": { "chromosome": "15", "start_pos": 81010218, "end_pos": 80991780, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043778.6", "url": "https://www.ensembl.org/id/ENSBTAT00000043778.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041323.6", "url": "https://www.ensembl.org/id/ENSBTAP00000041323.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:515187", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515187", "resource": "KEGG Pathway" }, { "id": "R-BTA-418990", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418990", "resource": "Reactome", "description": "Adherens junctions interactions" }, { "id": "R-BTA-5218920", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5218920", "resource": "Reactome", "description": "VEGFR2 mediated vascular permeability" }, { "id": "R-BTA-9762292", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9762292", "resource": "Reactome", "description": "Regulation of CDH11 function" }, { "id": "R-BTA-9764561", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9764561", "resource": "Reactome", "description": "Regulation of CDH1 Function" }, { "id": "R-BTA-9766229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9766229", "resource": "Reactome", "description": "Degradation of CDH1" }, { "id": "R-BTA-9958810", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958810", "resource": "Reactome", "description": "SRC activates STAT3 in a quantitative manner, through Cadherin-11 (CDH11), RAC1 and gp130 (IL6ST)" }, { "id": "R-BTA-9958825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958825", "resource": "Reactome", "description": "Activation of STAT3 by cadherin engagement" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUK1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUK1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUK1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUK1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUK1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUK1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUK1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" }, { "start_pos": 585, "end_pos": 587, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 763, "end_pos": 765, "annotation": "n_glycosylation_sequon" }, { "start_pos": 803, "end_pos": 805, "annotation": "n_glycosylation_sequon" }, { "start_pos": 807, "end_pos": 809, "annotation": "n_glycosylation_sequon" }, { "start_pos": 849, "end_pos": 851, "annotation": "n_glycosylation_sequon" }, { "start_pos": 897, "end_pos": 899, "annotation": "n_glycosylation_sequon" }, { "start_pos": 908, "end_pos": 910, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 434, "end_pos": 436 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 57, "end_pos": 59 }, { "start_pos": 585, "end_pos": 587 }, { "start_pos": 609, "end_pos": 611 }, { "start_pos": 635, "end_pos": 637 }, { "start_pos": 763, "end_pos": 765 }, { "start_pos": 803, "end_pos": 805 }, { "start_pos": 807, "end_pos": 809 }, { "start_pos": 849, "end_pos": 851 }, { "start_pos": 897, "end_pos": 899 }, { "start_pos": 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"length": 502, "header": "tr|A0ABI0NUD4-1|A0ABI0NUD4_BOVIN Isoform 1 of STEAP2 metalloreductase OS=Bos taurus OX=9913 GN=STEAP2 PE=3 SV=1 CANONICAL=A0ABI0NUD4-1" }, "locus": { "chromosome": "4", "start_pos": 74430654, "end_pos": 74414866, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146006.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146006.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107270.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107270.1" } ] } }, { "isoform_ac": "F6PVT9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUD4/entry#F6PVT9-1", "sequence": { "sequence": 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[], "interactions": [], "reactions": [ { "id": "R-BTA-140978", "name": "TRADD:TRAF2:RIP1 binds FADD", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q1RMU2-1", "Q2KHV7-1", "A0ABI0NXY8-1", "G3N2I1-1", "Q5E953-1", "A6QR55-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-140978", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-140978" } ] }, { "id": "R-BTA-5357776", "name": "TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q95KV1-1", "Q95KV0-1", "A0ABI0NI58-1", "Q1RMU2-1", "Q2KHV7-1", "A0ABI0NXY8-1", "E1BMK3-1", "G3N2I1-1", "Q5E953-1", "A6QR55-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5357776", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357776" } ] }, { "id": "R-BTA-5357845", "name": "K63polyUb-RIPK1 is deubiquitinated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "Q1RMU2-1", "Q2KHV7-1", "A0ABI0NXY8-1", "G3N2I1-1", "Q5E953-1", "A6QR55-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5357845", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357845" } ] }, { "id": "R-BTA-5357860", "name": "TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NI58-1", "Q1RMU2-1", "Q2KHV7-1", "A0ABI0NXY8-1", "E1BMK3-1", "G3N2I1-1", "Q5E953-1", "A2VDU3-1", "A6QR55-1", "E1B9D9-1" ], "evidence": [ { "id": "R-BTA-5357860", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357860" } ] }, { "id": "R-BTA-5690870", "name": "OTUD7B,TNFAIP3 deubiquitinate TRAF6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3ZCC3-1", "A0ABI0NXY8-1", "A6QP16-1" ], "evidence": [ { "id": "R-BTA-5690870", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5690870" } ] }, { "id": "R-BTA-8869506", "name": "TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3ZCC3-1", "A0ABI0NXY8-1", "A6QP16-1" ], "evidence": [ { "id": "R-BTA-8869506", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8869506" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0ABI0NI58", "gene_name": "XIAP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0ABI0NI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0ABI0NI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NI58" } ] } ] }, { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QR55" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "A6QR55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QR55" } ] } ] }, { "uniprot_ac": "E1B9D9", "gene_name": "TRAF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B9D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B9D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9D9" } ] } ] }, { "uniprot_ac": "E1BMK3", "gene_name": "RNF31", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P006-1", "uniprot_ac": "A0ABI0P006", "uniprot_id": "A0ABI0P006_BOVIN", "mass": { "chemical_mass": 27241.0, "monoisotopic_mass": 27241.0 }, "refseq": {}, "gene_names": [ { "name": "LOC785216", "type": "recommended", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] } ], "protein_names": [ { "name": "Glutathione S-transferase omega", "type": "recommended", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006/entry#names_and_taxonomy" } ] }, { "name": "1.20.4.2", "type": "synonym", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006/entry#names_and_taxonomy" } ] }, { "name": "1.8.5.1", "type": "synonym", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.18", "type": "synonym", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006/entry#names_and_taxonomy" } ] }, { "name": "GSTO", "type": "synonym", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006/entry#names_and_taxonomy" } ] }, { "name": "Glutathione-dependent dehydroascorbate reductase", "type": "synonym", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006/entry#names_and_taxonomy" } ] }, { "name": "Monomethylarsonic acid reductase", "type": "synonym", "evidence": [ { "id": "A0ABI0P006", 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Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid.", "evidence": [ { "database": "UniProtKB", "id": "E1BKU3", "url": "https://www.uniprot.org/uniprotkb/E1BKU3#function" }, { "database": "UniProtKB", "id": "ARBA00058491", "url": "https://www.uniprot.org/uniprotkb/ARBA00058491#function" }, { "database": "UniProtKB", "id": "A0ABI0NMB4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMB4#function" }, { "database": "UniProtKB", "id": "A0ABI0NWL3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWL3#function" }, { "database": "UniProtKB", "id": "A0ABI0P006", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006#function" }, { "database": "UniProtKB", "id": "E1BJ08", "url": "https://www.uniprot.org/uniprotkb/E1BJ08#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P006", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC785216", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000038540", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038540", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03184", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03184", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR43968", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43968", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43968:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43968:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00043", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00043", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13417", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13417", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14497", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14497", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-156581", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156581", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-156590", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156590", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-196836", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196836", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "15969", "url": "https://www.rhea-db.org/rhea/15969", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "16437", "url": "https://www.rhea-db.org/rhea/16437", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "24424", "url": "https://www.rhea-db.org/rhea/24424", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NMB4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMB4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWL3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWL3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P006", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P006-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ08", "url": "https://www.uniprot.org/uniprotkb/E1BJ08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJ08-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKU3", "url": "https://www.uniprot.org/uniprotkb/E1BKU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BKU3-1", "url": "https://www.uniprot.org/uniprotkb/E1BKU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGTVRSLGKGSAPPGPVPEGLIRVYSMRFCPYAQRTRLVLTAKGIRHEVININLKNKPEWFFKKNPSGLVPVLETSQGQLICESAITCEYLDEAYPGKKLLPGDPYEKACQKMVLESFSKVPPLILKILRTQNKEDCSGLKEELHKEITKLEEVLTDKKTTFFGGNSLSMIDYLIWPWFERLEALELNECVDHAPTLKLWMAAMKKDPTVSSLLTDVKTFQGFFNLYLQNSPEAYDYGL", "length": 241, "header": "tr|A0ABI0P006-1|A0ABI0P006_BOVIN Isoform 1 of Glutathione S-transferase omega OS=Bos taurus OX=9913 GN=LOC785216 PE=1 SV=1 CANONICAL=A0ABI0P006-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NMB4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006/entry#A0ABI0NMB4-1", "sequence": { "sequence": "MSGGTVRSLGKGSAPPGPVPEGLIRVYSMRFCPYAKRTLLVLRAKGIRHEVININLKNKPEWFFKKNPLGLVPVLETSLGQLIYESAITCEYLDEAYPGKKLLPGDPYEKACQKMVFESFSKVLTNKKTTFFGGSSLSMIDYLIWPWFEWLEALELNECVDHAPTLKLWMAAMKKDPTVSSLLTDVKTFQGFFNLYLQNSPEAYDYGL", "length": 208, "header": "tr|A0ABI0NMB4-1|A0ABI0P006_BOVIN Computationally mapped isoform of Glutathione S-transferase omega OS=Bos taurus OX=9913 GN=LOC785216 PE=1 SV=1 CANONICAL=A0ABI0P006-1" }, "locus": { "chromosome": "26", "start_pos": 24836104, "end_pos": 24799738, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154665.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154665.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106555.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106555.1" } ] } }, { "isoform_ac": "A0ABI0NWL3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006/entry#A0ABI0NWL3-1", "sequence": { "sequence": "MSGGTVRSLGKGSAPPGPVPEGLIRVYSMRFCPYAKRTLLVLRAKGIRHEVININLKNKPEWFFKKNPLGLVPVLETSLGQLIYESAITCEYLDEAYPGKKLLPGDPYEKACQKMVFESFSKVPSLMVSFLRKQNKEDCSGLKEELHKEFSKLEEVLTNKKTTFFGGSSLSMIDYLIWPWFEWLEALELNECVDHAPTLKLWMAAMKKDPTVSSLLTDVKTFQGFFNLYLQNSPEAYDYGL", "length": 241, "header": "tr|A0ABI0NWL3-1|A0ABI0NWL3_BOVIN Computationally mapped isoform of Glutathione S-transferase omega OS=Bos taurus OX=9913 GN=LOC785216 PE=1 SV=1 CANONICAL=A0ABI0P006-1" }, "locus": { "chromosome": "26", "start_pos": 24836104, "end_pos": 24799738, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142967.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142967.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104964.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104964.1" } ] } }, { "isoform_ac": "A0ABI0P006-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006/entry#A0ABI0P006-1", "sequence": { "sequence": "MSGGTVRSLGKGSAPPGPVPEGLIRVYSMRFCPYAQRTRLVLTAKGIRHEVININLKNKPEWFFKKNPSGLVPVLETSQGQLICESAITCEYLDEAYPGKKLLPGDPYEKACQKMVLESFSKVPPLILKILRTQNKEDCSGLKEELHKEITKLEEVLTDKKTTFFGGNSLSMIDYLIWPWFERLEALELNECVDHAPTLKLWMAAMKKDPTVSSLLTDVKTFQGFFNLYLQNSPEAYDYGL", "length": 241, "header": "tr|A0ABI0P006-1|A0ABI0P006_BOVIN Isoform 1 of Glutathione S-transferase omega OS=Bos taurus OX=9913 GN=LOC785216 PE=1 SV=1 CANONICAL=A0ABI0P006-1" }, "locus": { "chromosome": "26", "start_pos": 24836104, "end_pos": 24799738, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137618.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137618.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107388.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107388.1" } ] } }, { "isoform_ac": "E1BJ08-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006/entry#E1BJ08-1", "sequence": { "sequence": "MYCKGACSGNIGCDLPPGAQAAVVGSSFLERVGNPPARWVGSPKGLCAQISFQRPGSAGPCAHSPGRADGCPSLALLRKIGEARPTSWLNFKLHWELGLCCAAMSGGTVRSLGKGSAPPGPVPEGLIRVYSMRFCPYAKRTLLVLRAKGIRHEVININLKNKPEWFFKKNPLGLVPVLETSLGQLIYESAITCEYLDEAYPGKKLLPGDPYEKACQKMVFESFSKVPSLMVSFLRKQNKEDCSGLKEELHKEFSKLEEVLTNKKTTFFGGSSLSMIDYLIWPWFEWLEALELNECVDHTPNLKLWMASMKNDPIVSSLPTDVKTLQDFFNLYLQNSPEACDYGSAPPGPVPEGLIRVYSMRFCPYAQRTRLVLTAKGIRHEVININLKNKPEWFFKKNPSGLVPVLETSQGQLICESAITCEYLDEAYPGKKLLPGDPYEKACQKMVLESFSKVPPLILKILRTQNKEDCSGLKEELHKEITKLEEVLTDKKTTFFGGNSLSMIDYLIWPWFERLEALELNECVDHAPTLKLWMAAMKKDPTVSSLLTDVKTFQGFFNLYLQNSPEAYDYGL", "length": 572, "header": "tr|E1BJ08-1|A0ABI0P006_BOVIN Computationally mapped isoform of Glutathione S-transferase omega OS=Bos taurus OX=9913 GN=LOC785216 PE=1 SV=5 CANONICAL=A0ABI0P006-1" }, "locus": { "chromosome": "26", "start_pos": 24836104, "end_pos": 24799429, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017435.8", "url": "https://www.ensembl.org/id/ENSBTAT00000017435.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017435.8", "url": "https://www.ensembl.org/id/ENSBTAP00000017435.8" } ] } }, { "isoform_ac": "E1BKU3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006/entry#E1BKU3-1", "sequence": { "sequence": "MSGGSARSLGKGSAPPGPVPEGLIRVYSMRFCPYAQRTRLVLTAKGIRHEVININLKNKPEWFFKKNPSGLVPVLETSQGQLICESAITCEYLDEAYPGKKLLPGDPYEKACQKMVLESFSKVPPLILKILRTQNKEDCSGLKEELHKEITKLEEVLTDKKTTFFGGNSLSMIDYLIWPWFERLEALELNECVDHAPTLKLWMAAMKKDPTVSSLLTDVKTFQGFFNLYLQNSPEAYDYGL", "length": 241, "header": "tr|E1BKU3-1|A0ABI0P006_BOVIN Computationally mapped isoform of Glutathione S-transferase omega OS=Bos taurus OX=9913 GN=LOC785216 PE=1 SV=3 CANONICAL=A0ABI0P006-1" }, "locus": { "chromosome": "26", "start_pos": 24836104, "end_pos": 24828045, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046357.5", "url": "https://www.ensembl.org/id/ENSBTAT00000046357.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043664.4", "url": "https://www.ensembl.org/id/ENSBTAP00000043664.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-156581", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156581", "resource": "Reactome", "description": "Methylation" }, { "id": "R-BTA-156590", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156590", "resource": "Reactome", "description": "Glutathione conjugation" }, { "id": "R-BTA-196836", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196836", "resource": "Reactome", "description": "Vitamin C (ascorbate) metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P006", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ], "pmid": "" }, { "name": "glutathione dehydrogenase (ascorbate) activity", "id": "GO:0045174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045174", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P006", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ], "pmid": "" }, { "name": "methylarsonate reductase activity", "id": "GO:0050610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050610", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P006", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P006", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "L-ascorbic acid metabolic process", "id": "GO:0019852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019852", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P006", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P006", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15969", "name": "", "equation": "methylarsonate + 2 glutathione + H(+) = methylarsonous acid + glutathione disulfide + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BED9-1", "A0ABI0P006-1" ], "evidence": [ { "id": "15969", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15969" } ] }, { "id": "16437", "name": "", "equation": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18879-1", "F1MUX5-1", "F1MX44-1", "A0ABI0P5M0-1", "A0AAA9TW47-1", "F6QEM8-1", "A0ABI0P3R2-1", "A0AAF6Z0W3-1", "P28801-1", "Q2KJG4-1", "A0A3Q1LMV5-1", "F1MVX2-1", "Q28035-1", "Q9N0V4-1", "Q2NL00-1", "F1MXY2-1", "E1BED9-1", "A0ABI0P006-1", "Q5E9G0-1", "Q64L89-1", "A0A452DIU1-1", "F1MGZ9-1", "A0AAA9TXU3-1", "E1BJX2-1" ], "evidence": [ { "id": "16437", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16437" } ] }, { "id": "24424", "name": "", "equation": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5E9B7-1", "E1BED9-1", "A0ABI0P006-1" ], "evidence": [ { "id": "24424", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24424" } ] }, { "id": "R-BTA-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18879-1", "E1BED9-1", "A0ABI0P006-1", "A0ABI0P5M0-1", "A0A3Q1LMV5-1", "F1MGZ9-1", "F1MUX5-1", "F1MX44-1", "Q2NL00-1", "Q5E9G0-1", "A0A452DIU1-1" ], "evidence": [ { "id": "R-BTA-176054", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-176054" } ] }, { "id": "R-BTA-198813", "name": "GSTO dimers reduce DeHA to AscH-", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-198827" ], "output_participant_list": [ "R-ALL-198816" ], "enzyme_list": [ "E1BED9-1", "A0ABI0P006-1" ], "evidence": [ { "id": "R-BTA-198813", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-198813" } ] }, { "id": "R-BTA-5696230", "name": "GSTO1 dimer reduces methylarsonate to methylarsonite", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-5696214" ], "output_participant_list": [], "enzyme_list": [ "A0ABI0P006-1" ], "evidence": [ { "id": "R-BTA-5696230", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5696230" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-198816", "participant_name": "AscH- [cytosol]", "crossref": [ { "id": "44229109", "database": "PubChem Compound", "url": "" }, { "id": "50-81-7", "database": "CAS", "url": "" }, { "id": "ZINC000100006770", "database": "ZINC", "url": "" }, { "id": "C00072", "database": "COMPOUND", "url": "" }, { "id": "38290", "database": "ChEBI", "url": "" }, { "id": "ASCORBATE", "database": "AraCyc", "url": "" } ] }, { "participant_id": "R-ALL-198827", "participant_name": "DeHA [cytosol]", "crossref": [ { "id": "58539", "database": "ChEBI", "url": "" }, { "id": "L-DEHYDRO-ASCORBATE", "database": "RiceCyc", "url": "" }, { "id": "ZINC000100082301", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-5696214", "participant_name": "methylarsonate [cytosol]", "crossref": [ { "id": "33409", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LMV5", "gene_name": "LOC281806", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A3Q1LMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A3Q1LMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ] } ] }, { "uniprot_ac": "A0A452DIU1", "gene_name": "LOC327709", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A452DIU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A452DIU1" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A452DIU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A452DIU1" } ] } ] }, { "uniprot_ac": "A0AAA9TW47", "gene_name": "GSTK1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0AAA9TW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0AAA9TW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ] } ] }, { "uniprot_ac": "A0AAA9TXU3", "gene_name": "GSTZ1", "activity": [ { "ec_number": "5.2.1.2", "activity": "4-maleylacetoacetate = 4-fumarylacetoacetate.", "evidence": [ { "id": "A0AAA9TXU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXU3" } ] }, { "ec_number": "5.2.1.2", "activity": "", "evidence": [ { "id": "A0AAA9TXU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXU3" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0AAA9TXU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXU3" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0AAA9TXU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXU3" } ] } ] }, { "uniprot_ac": "A0AAF6Z0W3", "gene_name": "LANCL1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0AAF6Z0W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0W3" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0AAF6Z0W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0W3" } ] } ] }, { "uniprot_ac": "A0ABI0P006", "gene_name": "LOC785216", "activity": [ { "ec_number": "1.20.4.2", "activity": "methylarsonate + 2 glutathione + H(+) = methylarsonous acid + glutathione disulfide + H2O.", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "1.8.5.1", "activity": "", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "1.20.4.2", "activity": "", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] } ] }, { "uniprot_ac": "A0ABI0P3R2", "gene_name": "GSTT2", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0ABI0P3R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0ABI0P3R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2" } ] }, { "ec_number": "4.1.1.84", "activity": "D-dopachrome + H(+) = 5,6-dihydroxyindole + CO2.", "evidence": [ { "id": "A0ABI0P3R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2" } ] }, { "ec_number": "4.1.1.84", "activity": "", "evidence": [ { "id": "A0ABI0P3R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2" } ] } ] }, { "uniprot_ac": "A0ABI0P5M0", "gene_name": "GSTA1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0ABI0P5M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M0" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0ABI0P5M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M0" } ] } ] }, { "uniprot_ac": "E1BED9", "gene_name": "GSTO2", "activity": [ { "ec_number": "1.20.4.2", "activity": "methylarsonate + 2 glutathione + H(+) = methylarsonous acid + glutathione disulfide + H2O.", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "1.20.4.2", "activity": "", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "1.8.5.1", "activity": "", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] } ] }, { "uniprot_ac": "E1BJX2", "gene_name": "GSTT4", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "E1BJX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJX2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "E1BJX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJX2" } ] } ] }, { "uniprot_ac": "F1MGZ9", "gene_name": "HPGDS", "activity": [ { "ec_number": "5.3.99.2", "activity": "prostaglandin H2 = prostaglandin D2.", "evidence": [ { "id": "F1MGZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGZ9" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MGZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGZ9" } ] }, { "ec_number": "5.3.99.2", "activity": "", "evidence": [ { "id": "F1MGZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGZ9" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MGZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGZ9" } ] } ] }, { "uniprot_ac": "F1MUX5", "gene_name": "LOC100295687", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MUX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUX5" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MUX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUX5" } ] } ] }, { "uniprot_ac": "F1MVX2", "gene_name": "LANCL1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MVX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVX2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MVX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVX2" } ] } ] }, { "uniprot_ac": "F1MX44", "gene_name": "GSTA5", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MX44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX44" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MX44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX44" } ] } ] }, { "uniprot_ac": "F1MXY2", "gene_name": "MGST1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MXY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXY2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MXY2", "database": 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"evidence": [ { "id": "Q5E9B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9B7" } ] } ] }, { "uniprot_ac": "Q5E9G0", "gene_name": "GSTA4", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "Q5E9G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9G0" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "Q5E9G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9G0" } ] } ] }, { "uniprot_ac": "Q64L89", "gene_name": "MGST1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "Q64L89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q64L89" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "Q64L89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q64L89" } ] } ] }, { "uniprot_ac": "Q9N0V4", "gene_name": "GSTM1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "Q9N0V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0V4" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "Q9N0V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0V4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" }, { "id": "PS50405", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50405" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST C-terminal", "eco_id": "ECO_0000259", "start_pos": 106, "end_pos": 230, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" }, { 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26141.0, "monoisotopic_mass": 26141.0 }, "refseq": { "ac": "NP_001040004", "name": "vesicle transport protein SEC20", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001040004" }, "gene_names": [ { "name": "BNIP1", "type": "recommended", "evidence": [ { "id": "A0ABI0NZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZA1" } ] }, { "name": "BNIP1", "type": "synonym", "evidence": [ { "id": "NP_001040004", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001040004" } ] } ], "protein_names": [ { "name": "BCL2 interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0ABI0NZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZA1/entry#names_and_taxonomy" } ] }, { "name": "BCL2/adenovirus E1B 19kDa interacting protein 1", "type": "synonym", "evidence": [ { "id": "NP_001040004", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001040004" } ] }, { "name": "vesicle transport 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] }, { "id": "A0ABI0NN93-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZA1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZA1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZA1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQELEQSAKEQDKESEKQVLLQEVENHKKQMLSNQTSWRKANLTCKIAIDNLEKAELLQGGDLFRQRKTAKESLAQTSSAITESLMGISRMMSQQVQQSEEAMQTLVNSSRTILDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYILKKRLFPFL", "length": 228, "header": "tr|A0ABI0NZA1-1|A0ABI0NZA1_BOVIN Isoform 1 of BCL2 interacting protein 1 OS=Bos taurus OX=9913 GN=BNIP1 PE=3 SV=1 CANONICAL=A0ABI0NZA1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M736-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZA1/entry#A0A3Q1M736-1", "sequence": { "sequence": 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"MAAAQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQELEQSAKEQDKESEKQVLLQEVENHKKQMLRKTAKESLAQTSSAITESLMGISRMMSQQVQQSEEAMQTLVNSSRTILDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYILKKRLFPFL", "length": 194, "header": "tr|A0ABI0NN93-1|A0ABI0NZA1_BOVIN Computationally mapped isoform of BCL2 interacting protein 1 OS=Bos taurus OX=9913 GN=BNIP1 PE=3 SV=1 CANONICAL=A0ABI0NZA1-1" }, "locus": { "chromosome": "20", "start_pos": 4854164, "end_pos": 4841545, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149600.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149600.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107098.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107098.1" } ] } }, { "isoform_ac": "A0ABI0NZA1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZA1/entry#A0ABI0NZA1-1", "sequence": { "sequence": "MAAAQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQELEQSAKEQDKESEKQVLLQEVENHKKQMLSNQTSWRKANLTCKIAIDNLEKAELLQGGDLFRQRKTAKESLAQTSSAITESLMGISRMMSQQVQQSEEAMQTLVNSSRTILDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYILKKRLFPFL", "length": 228, "header": "tr|A0ABI0NZA1-1|A0ABI0NZA1_BOVIN Isoform 1 of BCL2 interacting protein 1 OS=Bos taurus OX=9913 GN=BNIP1 PE=3 SV=1 CANONICAL=A0ABI0NZA1-1" }, "locus": { "chromosome": "20", "start_pos": 4854164, "end_pos": 4841545, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144888.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144888.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106956.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106956.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614520", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614520", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZA1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZA1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZA1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZA1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZA1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZA1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NZA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZA1" }, { "id": "PF03908", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sec20 C-terminal", "eco_id": "ECO_0000259", "start_pos": 134, "end_pos": 224, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 91, "end_pos": 93 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NTZ4-1", "uniprot_ac": "A0ABI0NTZ4", "uniprot_id": "A0ABI0NTZ4_BOVIN", "mass": { "chemical_mass": 63876.0, "monoisotopic_mass": 63876.0 }, "refseq": { "ac": "XP_024833187", "name": "ETS-related transcription factor Elf-2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833187" }, "gene_names": [ { "name": "ELF2", "type": "recommended", "evidence": [ { "id": "A0ABI0NTZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4" } ] }, { "name": "ELF2", "type": "synonym", "evidence": [ { "id": "XP_024833187", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833187" } ] } ], "protein_names": [ { "name": "E74 like ETS transcription factor 2", "type": "synonym", "evidence": [ { "id": "A0ABI0NTZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4/entry#names_and_taxonomy" } ] }, { "name": "ETS-related transcription factor Elf-2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_024833187", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833187" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTZ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ELF2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4", "locus": { "chromosome": "17", "start_pos": 18574676, "end_pos": 18554569, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020594", "url": "https://www.ensembl.org/id/ENSBTAG00000020594" } ] } } ], "crossref": [ { "id": "ENSBTAG00000020594", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020594", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613439", "url": "https://www.ncbi.nlm.nih.gov/gene/613439", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M7R6", "url": "https://www.orthodb.org/?gene=A0A3Q1M7R6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M931", "url": "https://www.orthodb.org/?gene=A0A3Q1M931", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N599", "url": "https://www.orthodb.org/?gene=F1N599", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11849:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11849:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12310", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12310", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8939245", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8939245", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024833187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833187", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7R6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M931", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M931", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M931-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M931-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTZ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P789", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P789", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P789-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P789-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N599", "url": "https://www.uniprot.org/uniprotkb/F1N599", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N599-1", "url": "https://www.uniprot.org/uniprotkb/F1N599-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSAVVDSGGSILELPSNGVENQEESGKVSEYPAVIVEPVPSARLEQGYAAQVLVYDDETYMMQDVAEEQEVETENVETVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPVEVFVPPCVSTPEFIHAAMRPDVITETVVEVSTEESEPMDTSPIPTSPDSHEPMKKKKVGRKPKTQQSPISNGSPDLGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCSEDLAGATDEKSLERVSLSAESLLKAATSVRGGKNSSPLNCSRAEKGVARVVNITPPGHDASSRSPTTTTSVSATAAPRTVRVAMQVPVVMTSLGQKISTVAVQSVNAGAPLITSTSPTTAASPKVVIQTIPTVMPASTENGDKITMQPAKIITIPATQLAQCQLQTKSNLTGSGSINIVGTPLAVRALTPVSIAHGAPVMRLSVPPQQASGQTPPRVISAVIKGPEVKSEAVAKKQEHDVKTLQLVQEEKPADGNKTVTHVVVVSAPSALALPVTMKTEGLVTCEK", "length": 594, "header": "tr|A0ABI0NTZ4-1|A0ABI0NTZ4_BOVIN Isoform 1 of E74 like ETS transcription factor 2 OS=Bos taurus OX=9913 GN=ELF2 PE=3 SV=1 CANONICAL=A0ABI0NTZ4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M7R6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4/entry#A0A3Q1M7R6-1", "sequence": { "sequence": "MATSLHEGPTNQLDLLIRAVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPVEVFVPPCVSTPEFIHAAMRPDVITETVVEVSTEESEPMDTSPIPTSPDSHEPMKKKKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCSEDLAGATDEKSLERVSLSAESLLKAATSVRGGKNSSPLNCSRAEKGVARVVNITPPGHDASSRSPTTTTSVSATAAPRTVRVAMQVPVVMTSLGQKISTVAVQSVNAGAPLITSTSPTTAASPKVVIQTIPTVMPASTENGDKITMQPAKIITIPATQLAQCQLQTKSNLTGSGSINIVGTPLAVRALTPVSIAHGAPVMRLSVPPQQASGQTPPRVISAVIKGPEVKSEAVAKKQEHDVKTLQLVQEEKPADGNKTVTHVVVVSAPSALALPVTMKTEGLVTCEK", "length": 505, "header": "tr|A0A3Q1M7R6-1|A0ABI0NTZ4_BOVIN Computationally mapped isoform of E74 like ETS transcription factor 2 OS=Bos taurus OX=9913 GN=ELF2 PE=3 SV=2 CANONICAL=A0ABI0NTZ4-1" }, "locus": { "chromosome": "17", "start_pos": 18572979, "end_pos": 18554670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067427.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067427.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069901.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069901.2" } ] } }, { "isoform_ac": "A0A3Q1M931-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4/entry#A0A3Q1M931-1", "sequence": { "sequence": "MATSLHEGPTNQLDLLIRAVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPVEVFVPPCVSTPEFIHAAMRPDVITETVVEVSTEESEPMDTSPIPTSPDSHEPMKKKKVGRKPKTQQSPISNGSPDLGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCSEDLAGATDEKSLERVSLSAESLLKAATSVRGGKNSSPLNCSRAEKGVARVVNITPPGHDASSRSPTTTTSVSATAAPRTVRVAMQVPVVMTSLGQKISTVAVQSVNAGAPLITSTSPTTAASPKVVIQTIPTVMPASTENGDKITMQPAKIITIPATQLAQCQLQTKSNLTGSGSINIVGTPLAVRALTPVSIAHGAPVMRLSVPPQQASGQTPPRVISAVIKGPEVKSEAVAKKQEHDVKTLQLVQEEKPADGNKTVTHVVVVSAPSALALPVTMKTEGLVTCEK", "length": 534, "header": "tr|A0A3Q1M931-1|A0ABI0NTZ4_BOVIN Computationally mapped isoform of E74 like ETS transcription factor 2 OS=Bos taurus OX=9913 GN=ELF2 PE=3 SV=3 CANONICAL=A0ABI0NTZ4-1" }, "locus": { "chromosome": "17", "start_pos": 18572979, "end_pos": 18554670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074319.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074319.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066626.3", "url": "https://www.ensembl.org/id/ENSBTAP00000066626.3" } ] } }, { "isoform_ac": "A0ABI0NTZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4/entry#A0ABI0NTZ4-1", "sequence": { "sequence": "MTSAVVDSGGSILELPSNGVENQEESGKVSEYPAVIVEPVPSARLEQGYAAQVLVYDDETYMMQDVAEEQEVETENVETVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPVEVFVPPCVSTPEFIHAAMRPDVITETVVEVSTEESEPMDTSPIPTSPDSHEPMKKKKVGRKPKTQQSPISNGSPDLGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCSEDLAGATDEKSLERVSLSAESLLKAATSVRGGKNSSPLNCSRAEKGVARVVNITPPGHDASSRSPTTTTSVSATAAPRTVRVAMQVPVVMTSLGQKISTVAVQSVNAGAPLITSTSPTTAASPKVVIQTIPTVMPASTENGDKITMQPAKIITIPATQLAQCQLQTKSNLTGSGSINIVGTPLAVRALTPVSIAHGAPVMRLSVPPQQASGQTPPRVISAVIKGPEVKSEAVAKKQEHDVKTLQLVQEEKPADGNKTVTHVVVVSAPSALALPVTMKTEGLVTCEK", "length": 594, "header": "tr|A0ABI0NTZ4-1|A0ABI0NTZ4_BOVIN Isoform 1 of E74 like ETS transcription factor 2 OS=Bos taurus OX=9913 GN=ELF2 PE=3 SV=1 CANONICAL=A0ABI0NTZ4-1" }, "locus": { "chromosome": "17", "start_pos": 18572979, "end_pos": 18502521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137120.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137120.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106995.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106995.1" } ] } }, { "isoform_ac": "A0ABI0P789-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4/entry#A0ABI0P789-1", "sequence": { "sequence": "MLESGKVSEYPAVIVEPVPSARLEQGYAAQVLVYDDETYMMQDVAEEQEVETENVETVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPEFIHAAMRPDVITETVVEVSTEESEPMDTSPIPTSPDSHEPMKKKKAQRASQIIRSSAIVGRKPKTQQSPISNGSPDLGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCSEDLAGATDEKSLERVSLSAESLLKAATSVRGGKNSSPLNCSRAEKGVARVVNITPPGHDASSRSPTTTTSVSATAAPRTVRVAMQVPVVMTSLGQKISTVAVQSVNAGAPLITSTSPTTAASPKVVIQTIPTVMPASTENGDKITMQPAKIITIPATQLAQCQLQTKSNLTGSGSINIVGTPLAVRALTPVSIAHGAPVMRLSVPPQQASGQTPPRVISAVIKGPEVKSEAVAKKQEHDVKTLQLVQEEKPADGNKTVTHVVVVSAPSALALPVTMKTEGLVTCEK", "length": 573, "header": "tr|A0ABI0P789-1|A0ABI0P789_BOVIN Computationally mapped isoform of E74 like ETS transcription factor 2 OS=Bos taurus OX=9913 GN=ELF2 PE=3 SV=1 CANONICAL=A0ABI0NTZ4-1" }, "locus": { "chromosome": "17", "start_pos": 18572979, "end_pos": 18519671, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149882.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149882.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107381.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107381.1" } ] } }, { "isoform_ac": "F1N599-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4/entry#F1N599-1", "sequence": { "sequence": "MPLPSWVVFFYGGRMEKTRNVFVPLPRSVGESEKNVYFVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPVEVFVPPCVSTPEFIHAAMRPDVITETVVEVSTEESEPMDTSPIPTSPDSHEPMKKKKAQRASQIIRSSAIVGRKPKTQQSPISNGSPDLGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCSEDLAGATDEKSLERVSLSAESLLKAATSVRGGKNSSPLNCSRAEKGVARVVNITPPGHDASSRSPTTTTSVSATAAPRTVRVAMQVPVVMTSLGQKISTVAVQSVNAGAPLITSTSPTTAASPKVVIQTIPTVMPASTENGDKITMQPAKIITIPATQLAQCQLQTKSNLTGSGSINIVGTPLAVRALTPVSIAHGAPVMRLSVPPQQASGQTPPRVISAVIKGPEVKSEAVAKKQEHDVKTLQLVQEEKPADGNKTVTHVVVVSAPSALALPVTMKTEGLVTCEK", "length": 566, "header": "tr|F1N599-1|A0ABI0NTZ4_BOVIN Computationally mapped isoform of E74 like ETS transcription factor 2 OS=Bos taurus OX=9913 GN=ELF2 PE=3 SV=4 CANONICAL=A0ABI0NTZ4-1" }, "locus": { "chromosome": "17", "start_pos": 18572979, "end_pos": 18555461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000048348.6", "url": "https://www.ensembl.org/id/ENSBTAT00000048348.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000045405.5", "url": "https://www.ensembl.org/id/ENSBTAP00000045405.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 362, "start_aa": "Thr", "end_pos": 362, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr362", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-8939245", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8939245", "resource": "Reactome", "description": "RUNX1 regulates transcription of genes involved in BCR signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTZ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTZ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTZ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTZ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTZ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTZ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTZ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NTZ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTZ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 563, "end_pos": 565, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011613", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011613", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10749", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10749", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10749:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10749:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00723", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00723", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19292", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19292", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MEK8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MEK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLX4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLX4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWX5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWX5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGLMAEVSWKVLERRARTKRSDSVYEPLKSINLPRSDETLWDKLDHYYRIVKSTLLLYQSPTTGLFPTKTCGNDQKAKIHDSLYCAAGAWALALAYRRIDDDKGRTHELEHSAIKCMRGILYCYMRQADKVQQFKQDPRPTTCLHSIFNVHTGDEILSYEEYGHLQINAVSLYLLYLVEMISSGLQIIYNTDEVSFIQNLVFCVERVYRVPDFGVWERGSKYNNGSTELHSSSVGLAKAALEAINGFNLFGNQGCSWSVIFVDIDAHNRNRQTLCYVLPRESKNTDAALLPCISYPAFALDDEVLFSQTLDKVIRKLKGKYGFKRFLRDGYRTSLEDPNRRYYKPAEIKLFDGIECEFPIFFLYMMIDGVFRGNPKQVKEYQDLLTPVLHHTTEGYPVIPKYYYVPADFVEHEKRNPGSQKRFPSNCGRDGKLFLWGQALYVIAKLLADELISPKDIDPVQRFVPLQNQRNVSMRFSNQGPLENDLVVYVALIAESQRLQVFLNTYGIQTQTPQQVEPIQIWAQQELVKAYFHLGVNEKLGLCGRPDRPIGCLGTSKIYRILGKTVVCYPIIFDLSDFYMSQDVLLLIDDIKNALQFIKQYWKMHGRPLFLVLIREDNIRGSRFNPILDMLAAFKKGMIGGVKVHVDRLQTLISGAVVEQLDFLRISEIEELPEFKSFEELEVPKHSKVKRQSSTSNAPEQEQKPDVTMTEWRNKLTHEILQKLNDCSCLASQAILLGILLKREGPNFITKEGTVSDHIERVYRRAGSKKLWLAVRYGAAFTQKFSSSIAPHITTFLVHGKQVTLGAFGHEEEVISNPLSPGVIKNIIYYKCNTHDEREAVIQQELVIHIGWIISNNPELFSGMLKIRIGWIIHAMEYELQIRGGNKPARDLYQLSPSDVKQLLLDILQPQQNGRCWLNRRQIDGSLNRTPPGFYDRVWQILERTPNGIIVAGRHLPQQPTLSDMTMYEMNFSLLVEDMLGNIDQPKYRQIVVELLMVVSIVLERNPELEFQDKVDLDKLVKEAFHEFQKDESRLKEIEKQDDMTSFYNTPPLGKRGTCSYLTKVVMNLLLEGEVKPSNDDPCLVS", "length": 1087, "header": "tr|A0ABI0NWX5-1|A0ABI0NWX5_BOVIN Isoform 1 of Phosphorylase b kinase regulatory subunit OS=Bos taurus OX=9913 GN=PHKB PE=3 SV=1 CANONICAL=A0ABI0NWX5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MEK8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWX5/entry#A0A3Q1MEK8-1", "sequence": { "sequence": 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"length": 1057, "header": "tr|A0A3Q1MEK8-1|A0ABI0NWX5_BOVIN Computationally mapped isoform of Phosphorylase b kinase regulatory subunit OS=Bos taurus OX=9913 GN=PHKB PE=3 SV=2 CANONICAL=A0ABI0NWX5-1" }, "locus": { "chromosome": "18", "start_pos": 16091807, "end_pos": 15865527, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077595.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077595.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072601.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072601.2" } ] } }, { "isoform_ac": "A0ABI0NLX4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWX5/entry#A0ABI0NLX4-1", "sequence": { "sequence": "MASSPDPVVPSPAFLRSDSVYEPLKSINLPRSDETLWDKLDHYYRIVKSTLLLYQSPTTGLFPTKTCGNDQKAKIHDSLYCAAGAWALALAYRRIDDDKGRTHELEHSAIKCMRGILYCYMRQADKVQQFKQDPRPTTCLHSIFNVHTGDEILSYEEYGHLQINAVSLYLLYLVEMISSGLQIIYNTDEVSFIQNLVFCVERVYRVPDFGVWERGSKYNNGSTELHSSSVGLAKAALEAINGFNLFGNQGCSWSVIFVDIDAHNRNRQTLCYNTDAALLPCISYPAFALDDEVLFSQTLDKVIRKLKGKYGFKRFLRDGYRTSLEDPNRRYYKPAEIKLFDGIECEFPIFFLYMMIDGVFRGNPKQVKEYQDLLTPVLHHTTEGYPVIPKYYYVPADFVEHEKRNPGSQKRFPSNCGRDGKLFLWGQALYVIAKLLADELISPKDIDPVQRFVPLQNQRNVSMRFSNQGPLENDLVVYVALIAESQRLQVFLNTYGIQTQTPQQVEPIQIWAQQELVKAYFHLGVNEKLGLCGRPDRPIGCLGTSKIYRILGKTVVCYPIIFDLSDFYMSQDVLLLIDDIKNALQFIKQYWKMHGRPLFLVLIREDNIRGSRFNPILDMLAAFKKGMIGGVKVHVDRLQTLISGAVVEQLDFLRISEIEELPEFKSFEELEVPKHSKVKRQSSTSNAPEQEQKPDVTMTEWRNKLTHEILQKLNDCSCLASQAILLGILLKREGPNFITKEGTVSDHIERVYRRAGSKKLWSVVRHAASLLSKLVDSLAPSITNVLVQGKQVTLGAFGHEEEVISNPLSPGVIKNIIYYKCNTHDEREAVIQQELVIHIGWIISNNPELFSGMLKIRIGWIIHAMEYELQIRGGNKPARDLYQLSPSDVKQLLLDILQPQQNGRCWLNRRQIDGSLNRTPPGFYDRVWQILERTPNGIIVAGRHLPQQPTLSDMTMYEMNFSLLVEDMLGNIDQPKYRQIVVELLMVVSIVLERNPELEFQDKVDLDKLVKEAFHEFQKDESRLKEIEKQDDMTSFYNTPPLGKRGTCSYLTKVVMNLLLEGEVKPSNDDPCLVS", "length": 1075, "header": "tr|A0ABI0NLX4-1|A0ABI0NWX5_BOVIN Computationally mapped isoform of Phosphorylase b kinase regulatory subunit OS=Bos taurus OX=9913 GN=PHKB PE=3 SV=1 CANONICAL=A0ABI0NWX5-1" }, "locus": { "chromosome": "18", "start_pos": 16091807, "end_pos": 15867797, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138501.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138501.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106252.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106252.1" } ] } }, { "isoform_ac": "A0ABI0NWX5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWX5/entry#A0ABI0NWX5-1", "sequence": { "sequence": "MAGLMAEVSWKVLERRARTKRSDSVYEPLKSINLPRSDETLWDKLDHYYRIVKSTLLLYQSPTTGLFPTKTCGNDQKAKIHDSLYCAAGAWALALAYRRIDDDKGRTHELEHSAIKCMRGILYCYMRQADKVQQFKQDPRPTTCLHSIFNVHTGDEILSYEEYGHLQINAVSLYLLYLVEMISSGLQIIYNTDEVSFIQNLVFCVERVYRVPDFGVWERGSKYNNGSTELHSSSVGLAKAALEAINGFNLFGNQGCSWSVIFVDIDAHNRNRQTLCYVLPRESKNTDAALLPCISYPAFALDDEVLFSQTLDKVIRKLKGKYGFKRFLRDGYRTSLEDPNRRYYKPAEIKLFDGIECEFPIFFLYMMIDGVFRGNPKQVKEYQDLLTPVLHHTTEGYPVIPKYYYVPADFVEHEKRNPGSQKRFPSNCGRDGKLFLWGQALYVIAKLLADELISPKDIDPVQRFVPLQNQRNVSMRFSNQGPLENDLVVYVALIAESQRLQVFLNTYGIQTQTPQQVEPIQIWAQQELVKAYFHLGVNEKLGLCGRPDRPIGCLGTSKIYRILGKTVVCYPIIFDLSDFYMSQDVLLLIDDIKNALQFIKQYWKMHGRPLFLVLIREDNIRGSRFNPILDMLAAFKKGMIGGVKVHVDRLQTLISGAVVEQLDFLRISEIEELPEFKSFEELEVPKHSKVKRQSSTSNAPEQEQKPDVTMTEWRNKLTHEILQKLNDCSCLASQAILLGILLKREGPNFITKEGTVSDHIERVYRRAGSKKLWLAVRYGAAFTQKFSSSIAPHITTFLVHGKQVTLGAFGHEEEVISNPLSPGVIKNIIYYKCNTHDEREAVIQQELVIHIGWIISNNPELFSGMLKIRIGWIIHAMEYELQIRGGNKPARDLYQLSPSDVKQLLLDILQPQQNGRCWLNRRQIDGSLNRTPPGFYDRVWQILERTPNGIIVAGRHLPQQPTLSDMTMYEMNFSLLVEDMLGNIDQPKYRQIVVELLMVVSIVLERNPELEFQDKVDLDKLVKEAFHEFQKDESRLKEIEKQDDMTSFYNTPPLGKRGTCSYLTKVVMNLLLEGEVKPSNDDPCLVS", "length": 1087, "header": "tr|A0ABI0NWX5-1|A0ABI0NWX5_BOVIN Isoform 1 of Phosphorylase b kinase regulatory subunit OS=Bos taurus OX=9913 GN=PHKB PE=3 SV=1 CANONICAL=A0ABI0NWX5-1" }, "locus": { "chromosome": "18", "start_pos": 16091807, "end_pos": 15865527, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137883.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137883.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105182.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105182.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWX5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWX5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWX5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWX5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glycogen metabolic process", "id": "GO:0005977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005977", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWX5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWX5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 929, "end_pos": 931, "annotation": "n_glycosylation_sequon" }, { "start_pos": 972, "end_pos": 974, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NWX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWX5" }, { "id": "PF00723", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00723" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GH15-like", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 872, "start_aa": "Leu", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NWX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWX5" }, { "id": "PF19292", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19292" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphorylase b kinase regulatory subunit alpha/beta C-terminal", "eco_id": "ECO_0000259", "start_pos": 914, "end_pos": 1054, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 225, "end_pos": 227 }, { "start_pos": 472, "end_pos": 474 }, { "start_pos": 929, "end_pos": 931 }, { "start_pos": 972, "end_pos": 974 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NVB3-1", "uniprot_ac": "A0ABI0NVB3", "uniprot_id": "A0ABI0NVB3_BOVIN", "mass": { "chemical_mass": 60923.0, "monoisotopic_mass": 60923.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF8", "type": "recommended", "evidence": [ { "id": "A0ABI0NVB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3" } ] } ], "protein_names": [ { "name": "Zinc finger protein 8", "type": "recommended", "evidence": [ { "id": "A0ABI0NVB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MK82", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK82#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0ABI0NVB3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3#function" } ] }, { "annotation": "Transcriptional repressor. May modulate BMP and TGF-beta signal transduction, through its interaction with SMAD proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MK82", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK82#function" }, { "database": "UniProtKB", "id": "ARBA00056482", "url": "https://www.uniprot.org/uniprotkb/ARBA00056482#function" }, { "database": "UniProtKB", "id": "A0ABI0NVB3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3", "locus": { "chromosome": "18", "start_pos": 65616261, "end_pos": 65600696, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000052906", "url": "https://www.ensembl.org/id/ENSBTAG00000052906" } ] } } ], "crossref": [ { "id": "ENSBTAG00000052906", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000052906", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "617174", "url": "https://www.ncbi.nlm.nih.gov/gene/617174", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MK82", "url": "https://www.orthodb.org/?gene=A0A3Q1MK82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6PVZ0", "url": "https://www.orthodb.org/?gene=F6PVZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23232:SF163", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23232:SF163", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MK82", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MK82-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVB3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVB3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PVZ0", "url": "https://www.uniprot.org/uniprotkb/F6PVZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PVZ0-1", "url": "https://www.uniprot.org/uniprotkb/F6PVZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LDLGLEITELDFALLRDTWVIDSALVCPDAEPYEAPWPLRVRSLSLEPGLVLIFSRADPHHLCLSLFPGPELPKPDVISQLEQGAELWVAERGLPQGCRPGQEAALEGQPPAREQGLPEEKGQEGFLGEALCPTSSGEDWERAGWVRGPEQDQGHWQLKEVPVQDGSLRLGESLGRLPEVSRVERACVPESRGPSSERSPDAAREETGSPGPQPRSRHDRGEASTVARPVPEAELARGQAPDKPYKCADCGKSFNHNAHLTVHRRIHTGERPYACKECGKAFSQNSSLVQHERIHTGHKPYKCAECGKSFCHSTHLTVHRRIHTGEKPYACQDCGRAFNQNSSLGRHRRTHTGEKPFACSVCGKAFSRTTCLFLHLRTHTAERPYECSRCGKGFRHSSSLAQHQRKHAGDGPYDCRQRLLFAPAPSWPEPLSPGEGPPRSDRPFRCSQCGKGFTQSSHLIRHQITHTREQPRGRGRRRPQVRSRGGHLGRRPLGPPEESPGGGTKAGPPAGRALALFDLHEIMQEKNPVRVIGVEEPAMSTSVLFDIREST", "length": 551, "header": "tr|A0ABI0NVB3-1|A0ABI0NVB3_BOVIN Isoform 1 of Zinc finger protein 8 OS=Bos taurus OX=9913 GN=ZNF8 PE=3 SV=1 CANONICAL=A0ABI0NVB3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MK82-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3/entry#A0A3Q1MK82-1", "sequence": { "sequence": "MDPEEEAAALAMAMGPPVERLQEPVTFRDVAVDFTQEEWGQLGPAQRTLYRDVMLETFGHLLSVGPELPKPDVISQLEQGAELWVAERGLPQGCRPGQEAALEGQPPAREQGLPEEKGQEGFLGEALCPTSSGEDWERAGWVRGPEQDQGHWQLKEVPVQDGSLRLGESLGRLPEVSRVERACVPESRGPSSERSPDAAREETGSPGPQPRSRHDRGEASTVARPVPEAELARGQAPDKPYKCADCGKSFNHNAHLTVHRRIHTGERPYACKECGKAFSQNSSLVQHERIHTGHKPYKCAECGKSFCHSTHLTVHRRIHTGEKPYACQDCGRAFNQNSSLGRHRRTHTGEKPFACSVCGKAFSRTTCLFLHLRTHTAERPYECSRCGKGFRHSSSLAQHQRKHAGDGPYDCRQRLLFAPAPSWPEPLSPGEGPPRSDRPFRCSQCGKGFTQSSHLIRHQITHTREQPRGRGRRRPQVRSRGGHLGRRPLGPPEESPGGGTKAGPPAGRALALFDLHEIMQEKNPVRVIGVEEPAMSTSVLFDIREST", "length": 547, "header": "tr|A0A3Q1MK82-1|A0ABI0NVB3_BOVIN Computationally mapped isoform of Zinc finger protein 8 OS=Bos taurus OX=9913 GN=ZNF8 PE=3 SV=2 CANONICAL=A0ABI0NVB3-1" }, "locus": { "chromosome": "18", "start_pos": 65612241, "end_pos": 65600904, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083282.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083282.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071889.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071889.2" } ] } }, { "isoform_ac": "A0ABI0NVB3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3/entry#A0ABI0NVB3-1", "sequence": { "sequence": "LDLGLEITELDFALLRDTWVIDSALVCPDAEPYEAPWPLRVRSLSLEPGLVLIFSRADPHHLCLSLFPGPELPKPDVISQLEQGAELWVAERGLPQGCRPGQEAALEGQPPAREQGLPEEKGQEGFLGEALCPTSSGEDWERAGWVRGPEQDQGHWQLKEVPVQDGSLRLGESLGRLPEVSRVERACVPESRGPSSERSPDAAREETGSPGPQPRSRHDRGEASTVARPVPEAELARGQAPDKPYKCADCGKSFNHNAHLTVHRRIHTGERPYACKECGKAFSQNSSLVQHERIHTGHKPYKCAECGKSFCHSTHLTVHRRIHTGEKPYACQDCGRAFNQNSSLGRHRRTHTGEKPFACSVCGKAFSRTTCLFLHLRTHTAERPYECSRCGKGFRHSSSLAQHQRKHAGDGPYDCRQRLLFAPAPSWPEPLSPGEGPPRSDRPFRCSQCGKGFTQSSHLIRHQITHTREQPRGRGRRRPQVRSRGGHLGRRPLGPPEESPGGGTKAGPPAGRALALFDLHEIMQEKNPVRVIGVEEPAMSTSVLFDIREST", "length": 551, "header": "tr|A0ABI0NVB3-1|A0ABI0NVB3_BOVIN Isoform 1 of Zinc finger protein 8 OS=Bos taurus OX=9913 GN=ZNF8 PE=3 SV=1 CANONICAL=A0ABI0NVB3-1" }, "locus": { "chromosome": "18", "start_pos": 65612241, "end_pos": 65606381, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142541.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142541.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104172.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104172.1" } ] } }, { "isoform_ac": "F6PVZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3/entry#F6PVZ0-1", "sequence": { "sequence": "MDPEEEAAALAMAMGPPVERLQEPVTFRDVAVDFTQEEWGQLGPAQRTLYRDVMLETFGHLLSVGPELPKPDVISQLEQGAELWVAERGLPQGCRPALPLFPAACGVSVPWDNF", "length": 114, "header": "tr|F6PVZ0-1|A0ABI0NVB3_BOVIN Computationally mapped isoform of Zinc finger protein 8 OS=Bos taurus OX=9913 GN=ZNF8 PE=3 SV=3 CANONICAL=A0ABI0NVB3-1" }, "locus": { "chromosome": "18", "start_pos": 65607339, "end_pos": 65600904, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004508.7", "url": "https://www.ensembl.org/id/ENSBTAT00000004508.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004508.7", "url": "https://www.ensembl.org/id/ENSBTAP00000004508.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVB3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NVB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVB3" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 245, "end_pos": 272, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 285, "end_pos": 287 }, { "start_pos": 341, "end_pos": 343 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NZ79-1", "uniprot_ac": "A0ABI0NZ79", "uniprot_id": "A0ABI0NZ79_BOVIN", "mass": { "chemical_mass": 30281.0, "monoisotopic_mass": 30281.0 }, "refseq": {}, "gene_names": [ { "name": "NFYB", "type": "recommended", "evidence": [ { "id": "A0ABI0NZ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ79" } ] } ], "protein_names": [ { "name": "Nuclear transcription factor Y subunit beta", "type": "recommended", "evidence": [ { "id": "A0ABI0NZ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ79/entry#names_and_taxonomy" } ] }, { "name": "CAAT box DNA-binding protein subunit B", "type": "synonym", "evidence": [ { "id": "A0ABI0NZ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ79/entry#names_and_taxonomy" } ] }, { "name": "Nuclear transcription factor Y subunit B", "type": "synonym", "evidence": [ { "id": "A0ABI0NZ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ79/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.", "evidence": [ { "database": "UniProtKB", "id": "A0AAF6ZED3", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZED3#function" }, { "database": "UniProtKB", "id": "ARBA00025263", "url": "https://www.uniprot.org/uniprotkb/ARBA00025263#function" }, { "database": "UniProtKB", "id": "A0AAF7A855", "url": "https://www.uniprot.org/uniprotkb/A0AAF7A855#function" }, { "database": "UniProtKB", "id": "A0ABI0NZ79", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ79#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZ79", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ79" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NFYB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ79", "locus": { "chromosome": "5", "start_pos": 67769135, "end_pos": 67788166, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000030744", "url": "https://www.ensembl.org/id/ENSBTAG00000030744" } ] } } ], "crossref": [ { "id": "cd22907", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22907", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11064:SF195", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11064:SF195", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00808", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00808", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAF6ZED3", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZED3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZED3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZED3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7A855", "url": "https://www.uniprot.org/uniprotkb/A0AAF7A855", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7A855-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF7A855-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ79", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ79-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAICTGQICSIQHIDTAIFPSACHDYSAKILRIINRTKGEIGQRLDTFFRQVFLSTTDNTVLAYFMTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTDEAFTNQLPAGLITADGQQQNVMVYTTSYQQISGVQQIQFS", "length": 273, "header": "tr|A0ABI0NZ79-1|A0ABI0NZ79_BOVIN Isoform 1 of Nuclear transcription factor Y subunit beta OS=Bos taurus OX=9913 GN=NFYB PE=3 SV=1 CANONICAL=A0ABI0NZ79-1" }, "isoforms": [ { "isoform_ac": "A0AAF6ZED3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ79/entry#A0AAF6ZED3-1", "sequence": { "sequence": "MESEKLTPELGGRLRRTAVLVATFTATQGEHEGEIGQRLDTFFRQVFLSTTDNTVLAYFMTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTDEAFTNQLPAGLITADGQQQNVMVYTTSYQQISGVQQIQFS", "length": 266, "header": "tr|A0AAF6ZED3-1|A0ABI0NZ79_BOVIN Computationally mapped isoform of Nuclear transcription factor Y subunit beta OS=Bos taurus OX=9913 GN=NFYB PE=3 SV=1 CANONICAL=A0ABI0NZ79-1" }, "locus": { "chromosome": "5", "start_pos": 67787935, "end_pos": 67769554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043454.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043454.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041024.4", "url": "https://www.ensembl.org/id/ENSBTAP00000041024.4" } ] } }, { "isoform_ac": "A0AAF7A855-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ79/entry#A0AAF7A855-1", "sequence": { "sequence": "MQVKSESEVAQLCPTLRDPMDCRPPGSSVHGIFQARMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTDEAFTNQLPAGLITADGQQQNVMVYTTSYQQISGVQQIQFS", "length": 241, "header": "tr|A0AAF7A855-1|A0ABI0NZ79_BOVIN Computationally mapped isoform of Nuclear transcription factor Y subunit beta OS=Bos taurus OX=9913 GN=NFYB PE=3 SV=1 CANONICAL=A0ABI0NZ79-1" }, "locus": { "chromosome": "5", "start_pos": 67779124, "end_pos": 67769554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072034.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072034.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064444.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064444.2" } ] } }, { "isoform_ac": "A0ABI0NZ79-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ79/entry#A0ABI0NZ79-1", "sequence": { "sequence": 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"total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NYA0-1", "uniprot_ac": "A0ABI0NYA0", "uniprot_id": "A0ABI0NYA0_BOVIN", "mass": { "chemical_mass": 58855.0, "monoisotopic_mass": 58855.0 }, "refseq": {}, "gene_names": [ { "name": "COQ8B", "type": "recommended", "evidence": [ { "id": "A0ABI0NYA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA0" } ] } ], "protein_names": [ { "name": "Coenzyme Q8B", "type": "synonym", "evidence": [ { "id": "A0ABI0NYA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYA0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "COQ8B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA0", "locus": { "chromosome": "18", "start_pos": 49974902, "end_pos": 49992306, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019462", "url": "https://www.ensembl.org/id/ENSBTAG00000019462" } ] } } ], "crossref": [ { "id": "ENSBTAG00000019462", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019462", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13970", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13970", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR43851", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43851", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43851:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43851:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03109", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03109", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NYA0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYA0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0V7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0V7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0V7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1B0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1B0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B8K5", "url": "https://www.uniprot.org/uniprotkb/E1B8K5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B8K5-1", "url": "https://www.uniprot.org/uniprotkb/E1B8K5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWQEVGGLLRATCGQLGRTIGRPCGALGPGPRCWGPCGDFGAQKLHHDGPGRGLGEEDIRKAREARIRKTPRPQVSLASEHSGPPLPSPGLAVSLGLGALAEVAKKSLLGGGVQSEGGSQPGSSLFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQRIFERVRQSADFMPRWQMLRVLEEELGGDWQAKVASLEEVPFAAASIGQVHQGVLRDGTEVAVKIQYPGVAQSIQSDVQNLLAVLKMSVALPEGLFAEQSLQALQRELAWECDYRREAACAQNFRQLLADDPFFRVPAVIQELCTTRVLGMELAGGVPLDQCQGLSQDIRNQICFQLLRLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVMAAANGDKDRVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGAGDTARRVQGLIPVLLRHRLRPPPEETYALHRKLAGAFLACARLRAQIACRDLFQDTYHRYWASRPIRETPSQDSSPIAGHPLL", "length": 535, "header": "tr|A0ABI0NYA0-1|A0ABI0NYA0_BOVIN Isoform 1 of Coenzyme Q8B OS=Bos taurus OX=9913 GN=COQ8B PE=3 SV=1 CANONICAL=A0ABI0NYA0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NYA0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA0/entry#A0ABI0NYA0-1", "sequence": { "sequence": "MWQEVGGLLRATCGQLGRTIGRPCGALGPGPRCWGPCGDFGAQKLHHDGPGRGLGEEDIRKAREARIRKTPRPQVSLASEHSGPPLPSPGLAVSLGLGALAEVAKKSLLGGGVQSEGGSQPGSSLFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQRIFERVRQSADFMPRWQMLRVLEEELGGDWQAKVASLEEVPFAAASIGQVHQGVLRDGTEVAVKIQYPGVAQSIQSDVQNLLAVLKMSVALPEGLFAEQSLQALQRELAWECDYRREAACAQNFRQLLADDPFFRVPAVIQELCTTRVLGMELAGGVPLDQCQGLSQDIRNQICFQLLRLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVMAAANGDKDRVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGAGDTARRVQGLIPVLLRHRLRPPPEETYALHRKLAGAFLACARLRAQIACRDLFQDTYHRYWASRPIRETPSQDSSPIAGHPLL", "length": 535, "header": "tr|A0ABI0NYA0-1|A0ABI0NYA0_BOVIN Isoform 1 of Coenzyme Q8B OS=Bos taurus OX=9913 GN=COQ8B PE=3 SV=1 CANONICAL=A0ABI0NYA0-1" }, "locus": { "chromosome": "18", "start_pos": 49992107, "end_pos": 49975279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154912.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154912.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105977.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105977.1" } ] } }, { "isoform_ac": "A0ABI0P0V7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA0/entry#A0ABI0P0V7-1", "sequence": { "sequence": "MWQEVGGLLRATCGQLGRTIGRPCGALGPGPRCWGPCGDFGAQKLHHDGPGRGLGEEDIRKAREARIRKTPRPQVSLASEHSGPPLPSPGLAVSLGLGALAEVAKKSLLGGGVQSEGGSQPGSSLFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQRIFERVRQSADFMPRWQMLRVLEEELGGDWQAKVASLEEVPFAAASIGQVHQGVLRDGTEVAVKIQYPGVAQSIQSDVQNLLAVLKMSVALPEGLFAEQSLQALQRELAWECDYRREAACAQNFRQLLADDPFFRVPAVIQELCTTRVLGMELAGGVPLDQCQGLSQDIRNQICFQLLRLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVMAAANGDKDRVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGAGDTARRVQGLIPVLLRHRLRPPPEETYALHRKLAGAFLACARLRAQIACRDLFQDTYHPS", "length": 512, "header": "tr|A0ABI0P0V7-1|A0ABI0P0V7_BOVIN Computationally mapped isoform of Coenzyme Q8B OS=Bos taurus OX=9913 GN=COQ8B PE=3 SV=1 CANONICAL=A0ABI0NYA0-1" }, "locus": { "chromosome": "18", "start_pos": 49992107, "end_pos": 49975347, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150998.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150998.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106536.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106536.1" } ] } }, { "isoform_ac": "A0ABI0P1B0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA0/entry#A0ABI0P1B0-1", "sequence": { "sequence": "MWQEVGGLLRATCGQLGRTIGRPCGALGPGPRCWGPCGDFGAQKLHHDGPGRGLGEEDIRKAREARIRKTPRPQVSLHTTQTQVPASRISRLANFGEGGSQPGSSLFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQRIFERVRQSADFMPRWQMLRVLEEELGGDWQAKVASLEEVPFAAASIGQVHQGVLRDGTEVAVKIQYPGVAQSIQSDVQNLLAVLKMSVALPEGLFAEQSLQALQRELAWECDYRREAACAQNFRQLLADDPFFRVPAVIQELCTTRVLGMELAGGVPLDQCQGLSQDIRNQICFQLLRLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVMAAANGDKDRVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGAGDTARRVQGLIPVLLRHRLRPPPEETYALHRKLAGAFLACARLRAQIACRDLFQDTYHRYWASRQTPSQDSSPIAGHPLL", "length": 513, "header": "tr|A0ABI0P1B0-1|A0ABI0P1B0_BOVIN Computationally mapped isoform of Coenzyme Q8B OS=Bos taurus OX=9913 GN=COQ8B PE=3 SV=1 CANONICAL=A0ABI0NYA0-1" }, "locus": { "chromosome": "18", "start_pos": 49992107, "end_pos": 49975279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137800.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137800.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104400.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104400.1" } ] } }, { "isoform_ac": "E1B8K5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA0/entry#E1B8K5-1", "sequence": { "sequence": "MWQEVGGLLRATCGQLGRTIGRPCGALGPGPRCWGPCGDFGAQKLHHDGPGRGLGEEDIRKAREARIRKTPRPQVSLASEHSGPPLPSPGLAVSLGLGALAEVAKKSLLGGGVQSEGGSQPGSSLFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQRIFERVRQSADFMPRWQMLRVLEEELGGDWQAKVASLEEVPFAAASIGQVHQGVLRDGTEVAVKIQYPGVAQSIQSDVQNLLAVLKMSVALPEGLFAEQSLQALQRELAWECDYRREAACAQNFRQLLADDPFFRVPAVIQELCTTRVLGMELAGGVPLDQCQGLSQDIRNQICFQLLRLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVMAAANGDKDRVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGAGDTARRVQGLIPVLLRHRLRPPPEETYALHRKLAGAFLACARLRAQIACRDLFQDTYHRYWASRQA", "length": 518, "header": "tr|E1B8K5-1|A0ABI0NYA0_BOVIN Computationally mapped isoform of Coenzyme Q8B OS=Bos taurus OX=9913 GN=COQ8B PE=3 SV=5 CANONICAL=A0ABI0NYA0-1" }, "locus": { "chromosome": "18", "start_pos": 49992107, "end_pos": 49975368, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025929.8", "url": "https://www.ensembl.org/id/ENSBTAT00000025929.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025929.8", "url": "https://www.ensembl.org/id/ENSBTAP00000025929.8" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYA0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA0" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYA0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NYA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA0" }, { "id": "PF03109", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03109" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC1 atypical kinase-like", "eco_id": "ECO_0000259", "start_pos": 172, "end_pos": 412, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24522", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24522", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SPX4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPX4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THD6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THD6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THY9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THY9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNC8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNC8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS53", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS53-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYA5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYA5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QQB6", "url": "https://www.uniprot.org/uniprotkb/F6QQB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QQB6-1", "url": "https://www.uniprot.org/uniprotkb/F6QQB6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGPEDSTGQPGPADRSHRSSVSSVGARAADVLVYLADDSMVPLAVENLPSLSAHELHRAIREVLQLPDIALDAFALWLVSPLLEVQLKPKHQPYKLGRQWQELLLRFTDAPDDDVAMDEPSLQFRRNVFFPKRRELQIHDKEVLRLLYEEAKGNVLASRYPCDVEDCEALGALVCRVQLGPYQPGQPTACALREKLDSFLPAHLCKRGHGLFAALRGRGAKAGTGEQGLLNAYRRVQEAAGSDGEREASLSPHYRAYLLKCHELPFYGCAFFHGEIDKPAQGFLHRGGRKPVSVAISLDGVHVIDCREKHVLLGLRFQELSWDHTSPEEEESVLWLEFDGDNEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAASQEAGPTSASGSSPPPHQRPQLRRQGSVVCSRIQHLSTIDYVEEGETIKRVKPKRTTSFFSRQLSLGQGSYTVVQPADSLEQG", "length": 463, "header": "tr|A0ABI0NYA5-1|A0ABI0NYA5_BOVIN Isoform 1 of FERM domain-containing protein 8 OS=Bos taurus OX=9913 GN=FRMD8 PE=4 SV=1 CANONICAL=A0ABI0NYA5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SPX4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA5/entry#A0AAA9SPX4-1", "sequence": { "sequence": "MDGPEDSTGQPGPADRSHRSSVSSVGARAADVLVYLADDSMVPLAVENLPSLSAHELHRAIREVLQLPDIALDAFALWLVSPLLDEPSLQFRRNVFFPKRRELQIHDKEVLRLLYEEAKGNVLASRYPCDVEDCEALGALVCRVQLGPYQPGQPTACALREKLDSFLPAHLCKRGHGLFAALRGRGAKAGTGEQGLLNAYRRVQEAAGSDGEREASLSPHYRAYLLKCHELPFYGCAFFHGEIDKPAQGFLHRGGRKPVSVAISLDGVHVIDCREKHVLLGLRFQELSWDHTSPEEEESVLWLEFDGDNEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAASQEAGPTSASGSSPPPHQRPQLRRQGSVVCSRIQHLSTIDYVEEGETIKRVKPKRTTSFFSRQLSLGQGSYTVVQPADSLEQG", "length": 429, "header": "tr|A0AAA9SPX4-1|A0ABI0NYA5_BOVIN Computationally mapped isoform of FERM domain-containing protein 8 OS=Bos taurus OX=9913 GN=FRMD8 PE=4 SV=1 CANONICAL=A0ABI0NYA5-1" }, "locus": { "chromosome": "29", "start_pos": 43601747, "end_pos": 43582483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121646.2", "url": "https://www.ensembl.org/id/ENSBTAT00000121646.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086037.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086037.1" } ] } }, { "isoform_ac": "A0AAA9THD6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA5/entry#A0AAA9THD6-1", "sequence": { "sequence": "MDGPEDSTGQPGPADRSHRSSVSSVGAREVQLKPKHQPYKLGRQWQELLLRFTDAPDDDVAMDEPSLQFRRNVFFPKRRELQIHDKEVLRLLYEEAKGNVLASRYPCDVEDCEALGALVCRVQLGPYQPGQPTACALREKLDSFLPAHLCKRGHGLFAALRGRGAKAGTGEQGLLNAYRRVQEAAGSDGEREASLSPHYRAYLLKCHELPFYGCAFFHGEIDKPAQGFLHRGGRKPVSVAISLDGVHVIDCREKHVLLGLRFQELSWDHTSPEEEESVLWLEFDGDNEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAASQEAGPTSASGSSPPPHQRPQLRRQGSVVCSRIQHLSTIDYVEEGETIKRVKPKRTTSFFSRQLSLGQGSYTVVQPADSLEQG", "length": 407, "header": "tr|A0AAA9THD6-1|A0ABI0NYA5_BOVIN Computationally mapped isoform of FERM domain-containing protein 8 OS=Bos taurus OX=9913 GN=FRMD8 PE=4 SV=1 CANONICAL=A0ABI0NYA5-1" }, "locus": { "chromosome": "29", "start_pos": 43601747, "end_pos": 43582483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104821.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104821.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095631.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095631.1" } ] } }, { "isoform_ac": "A0AAA9THY9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA5/entry#A0AAA9THY9-1", "sequence": { "sequence": "MDGPEDSTGQPGPADRSHRSSVSSVGARAADVLVYLADDSMVPLAVENLPSLSAHELHRAIREVLQLPDIALDAFALWLVSPLLEVQLKPKHQPYKLGRQWQELLLRFTDAPDDDVAMDEPSLQFRRNVFFPKRRELQIHDKEVLRLLYEEAKGNVLASRYPCDVEDCEALGALVCRVQLGPYQPGQPTACALREKLDSFLPAHLCKRGHGLFAALRGRGAKAGTGEQGLLNAYRRVQEAAGSDGEREASLSPHYRAYLLKCHELPFYGCAFFHGEIDKPAQGFLHRGGRKPVSVAISLDGVHVIDCREKHVLLGLRFQELSWDHTSPEEEESVLWLEFDGDNEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAASQEAGPTSASGSSPPPHQRPQLRRQGSVVCSRIQHLSTIDYVEEDAWSHPEHHTSCGCCVSLGSSWL", "length": 447, "header": "tr|A0AAA9THY9-1|A0ABI0NYA5_BOVIN Computationally mapped isoform of FERM domain-containing protein 8 OS=Bos taurus OX=9913 GN=FRMD8 PE=4 SV=1 CANONICAL=A0ABI0NYA5-1" }, "locus": { "chromosome": "29", "start_pos": 43600553, "end_pos": 43582483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101698.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101698.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096715.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096715.1" } ] } }, { "isoform_ac": "A0AAA9TNC8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA5/entry#A0AAA9TNC8-1", "sequence": { "sequence": "MDGPEDSTGQPGPADRSHRSSVSSVGARAADVLVYLADDSMVPLAVENLPSLSAHELHRAIREVLQLPDIALDAFALWLVSPLLEVQLKPKHQPYKLGRQWQELLLRFTDAPDDDVAMDEPSLQFRRNVFFPKRRELQIHDKEVLRLLYEEAKGNVLASRYPCDVEDCEALGALVCRVQLGPYQPGQPTACALREKLDSFLPAHLCKRGHGLFAALRGRGAKAGTGEQGLLNAYRRVQEAAGSDGEREASLSPHYRAYLLKCHELPFYGCAFFHGEIDKPAQGFLHRGGRKPVSVAISLDGVHVIDCREKHVLLGLRFQELSWDHTSPEEEESVLWLEFDGDNEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAASQEAGPTSASGSSPPPHQRPQLRRQGSVVCSRIQHLSTIDYVEEGLVSPTHLRKCQDKTDEPDLGEK", "length": 447, "header": "tr|A0AAA9TNC8-1|A0ABI0NYA5_BOVIN Computationally mapped isoform of FERM domain-containing protein 8 OS=Bos taurus OX=9913 GN=FRMD8 PE=4 SV=1 CANONICAL=A0ABI0NYA5-1" }, "locus": { "chromosome": "29", "start_pos": 43610974, "end_pos": 43582483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124463.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124463.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099860.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099860.1" } ] } }, { "isoform_ac": "A0AAA9TS53-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA5/entry#A0AAA9TS53-1", "sequence": { "sequence": "MDGPEDSTGQPGPADRSHRSSVSSVGARAADVLVYLADDSMVPLAVENLPSLSAHELHRAIREVLQLPDIALDAFALWLVSPLLEVQLKPKHQPYKLGRQWQELLLRFTDAPDDDVAMDEPSLQFRRNVFFPKRRELQIHDKEVLRLLYEEAKGNVLASRYPCDVEDCEALGALVCRVQLGPYQPGQPTACALREKLDSFLPAHLCKRGHGLFAALRGRGAKAGTGEQGLLNAYRRVQEAAGSDGEREASLSPHYRAYLLKCHELPFYGCAFFHGEIDKPAQGFLHRGGRKPVSVAISLDGVHVIDCREKHVLLGLRFQELSWDHTSPEEEESVLWLEFDGDNEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAASQEAGPTSASGSSPPPHQRPQLRRQGSVVCSRIQHLSTIDYVEEVVKNPPAVQEMQF", "length": 437, "header": "tr|A0AAA9TS53-1|A0ABI0NYA5_BOVIN Computationally mapped isoform of FERM domain-containing protein 8 OS=Bos taurus OX=9913 GN=FRMD8 PE=4 SV=1 CANONICAL=A0ABI0NYA5-1" }, "locus": { "chromosome": "29", "start_pos": 43599051, "end_pos": 43582483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122918.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122918.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099309.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099309.1" } ] } }, { "isoform_ac": "A0ABI0NYA5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA5/entry#A0ABI0NYA5-1", "sequence": { "sequence": "MDGPEDSTGQPGPADRSHRSSVSSVGARAADVLVYLADDSMVPLAVENLPSLSAHELHRAIREVLQLPDIALDAFALWLVSPLLEVQLKPKHQPYKLGRQWQELLLRFTDAPDDDVAMDEPSLQFRRNVFFPKRRELQIHDKEVLRLLYEEAKGNVLASRYPCDVEDCEALGALVCRVQLGPYQPGQPTACALREKLDSFLPAHLCKRGHGLFAALRGRGAKAGTGEQGLLNAYRRVQEAAGSDGEREASLSPHYRAYLLKCHELPFYGCAFFHGEIDKPAQGFLHRGGRKPVSVAISLDGVHVIDCREKHVLLGLRFQELSWDHTSPEEEESVLWLEFDGDNEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAASQEAGPTSASGSSPPPHQRPQLRRQGSVVCSRIQHLSTIDYVEEGETIKRVKPKRTTSFFSRQLSLGQGSYTVVQPADSLEQG", "length": 463, "header": "tr|A0ABI0NYA5-1|A0ABI0NYA5_BOVIN Isoform 1 of FERM domain-containing protein 8 OS=Bos taurus OX=9913 GN=FRMD8 PE=4 SV=1 CANONICAL=A0ABI0NYA5-1" }, "locus": { "chromosome": "29", "start_pos": 43601747, "end_pos": 43582483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144950.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144950.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105215.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105215.1" } ] } }, { "isoform_ac": "F6QQB6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA5/entry#F6QQB6-1", "sequence": { "sequence": "MVPLAVENLPSLSAHELHRAIREVLQLPDIALDAFALWLVSPLLEVQLKPKHQPYKLGRQWQELLLRFTDAPDDDVAMDEPSLQFRRNVFFPKRRELQIHDKEVLRLLYEEAKGNVLASRYPCDVEDCEALGALVCRVQLGPYQPGQPTACALREKLDSFLPAHLCKRGHGLFAALRGRGAKAGTGEQGLLNAYRRVQEAAGSDGEREASLSPHYRAYLLKCHELPFYGCAFFHGEIDKPAQGFLHRGGRKPVSVAISLDGVHVIDCREKHVLLGLRFQELSWDHTSPEEEESVLWLEFDGDNEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAASQEAGPTSASGSSPPPHQRPQLRRQGSVVCSRIQHLSTIDYVEEGETIKRVKPKRTTSFFSRQLSLGQGSYTVVQPADSLEQG", "length": 423, "header": "tr|F6QQB6-1|A0ABI0NYA5_BOVIN Computationally mapped isoform of FERM domain-containing protein 8 OS=Bos taurus OX=9913 GN=FRMD8 PE=4 SV=2 CANONICAL=A0ABI0NYA5-1" }, "locus": { "chromosome": "29", "start_pos": 43601747, "end_pos": 43584241, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000033253.5", "url": "https://www.ensembl.org/id/ENSBTAT00000033253.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000033173.5", "url": "https://www.ensembl.org/id/ENSBTAP00000033173.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A480S6K5-1", "protein_name": "FERM domain-containing protein 8", "gene_name": "FRMD8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGTEGNAGQPGPADRSHRSSVSSMGARAADVLVYLADDSVVPLAVENLPSLSAHELHRAIREVLQLPDIALDAFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTDAPDDDVAVDEPSLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNLLAARYPCDVEDCEALGALVCRMQLGPYQPGQPTACALREKLDSFLPAHLCKRGHGLFAALRGRGAKAGPVEQGLLDAYRRVQDVGNSEASLSPHYRAYLLKCHELPFYGCAFFHGEIDKPAQGFLHRGGRKPVSVAISLEGVHVIDSREKHVLLGLRFQELSWDHTSPEEEESVLWLEFDGDHEGTPVNKLLKIYSKQAELMSSLIEYCIELNQTSEPAAAQESASGPAPAPGPSPLPTRRPQLRRQGSVVCSRIQHLATIDYVEEGEQIKRVKPKRTTSFFSRQLSLGQGSYTVVQPSDSLEQG", "length": 461 }, "evidence": [ { "id": "A0ABI0NYA5", "url": "https://omabrowser.org/oma/group/A0ABI0NYA5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0X097-1", "protein_name": "FERM domain-containing protein 8", "gene_name": "FRMD8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPEPEPEPEAAASGAVAAVRVFLPDGSAVPLALPPPVLGLTAAVLLRCLWDTAGLGPEGCAAMALWLVSGLLEVQLKPRQQPFRLRRQWAELVLRLSDAPPGAVARDEPCLHLRRNVFFPKHKELELQDEAVLRLLVAEARGHLRGGRWPLPPQEAVELGGLQCRLHFGPFQPGQHSAESLRPALEELLPPTPRGRFWGSLRRRPPGPPPEELLNAFSRTPGPETPPAELLRSFLQGCHRLHGYGCAFFPGAIDRPPGGLLGRGGLRPVNVAVGLEGVTIIDAREKHVLLTLSYPELSWELVGAVGQDGDAAEGLGGADAAEPPQLWLEFDGEQEGARVNRLLRVLSPQAELMSALIECCIALGGTEPPLSPPQRRPRPQRLATIDYVEDGAELRRVKPPRRSASFFGRMGVRGGSEDEAAGGAPGAPQDRTGEPH", "length": 437 }, "evidence": [ { "id": "A0ABI0NYA5", "url": "https://omabrowser.org/oma/group/A0ABI0NYA5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7F221-1", "protein_name": "FERM domain-containing protein 8", "gene_name": "frmd8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEGDDGDFPPEPSEHSLSQRGSVASSVTRAQDLLVYLANDSAVHLTLEGLGCMNAQELGRSVREALNIPNSAADVFAFWFCSPLLELQLKPKHLPYKLCRQWQDLLYRFTEAPTEDISLDEPSLLFKRSVFYPRAKELQIEDEGVLRLLYDEAKMNILEGRYPCDPEHWLTLGALSCAIELGTELDDQALTAAIREKKLSSFLPAHAALGGGGFLSTLRGRGGRNAEMEQNLVKECRSVCSSAASGSSQEPIALLRQYLRSCHNLPYYGCAFFAGEIDKPAQGLLHRGGRKAVSVGISLEGVYVMDVKEKHVLLGLKFTELSWDHSYPETEGDSHILWLEFDGEEAGTPVNKLLKIYSKQAELMSGLIEFCVELRSVSESAATGTDGEVTPSHEPTSPETNNKTRERRQGKLRRQNSVVCSRVHSLSTINYVDDGKEIKRLKPKRAASFFTRQAQPPTYSAVQVTESLEQG", "length": 471 }, "evidence": [ { "id": "A0ABI0NYA5", "url": "https://omabrowser.org/oma/group/A0ABI0NYA5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3UFK8-1", "protein_name": "FERM domain-containing protein 8", "gene_name": "Frmd8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGAEGNAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLSSISAHELHRAVREVLQLPDVALEAFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTNASDDDVAMDEPSLQFRRNVFFPRRRELQIHDEEVLRLLYEEAKGNVLTARYPCDLEDCEVLGGLVCRVQLGPYQPGQPAACTLREKLDSFLPAHLCKRGHGLFAAFRGRGAKTGPGEQGLLNAYRQVKEVTGNNSEREATLGSHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVTVAISLEGVHVIDNREKHVLLGLRFQELSWDHTSPEEEEPVLWLEFDGDSEGTPVNKLLRIYSKQAELMSGLIEYCIELSQAAEPTLSQESASGPHEAPSPSPPPTQRPKLRRQGSVVCSRIQHLSTIDYVEDGKGIKRVKPKRTTSFFSRQLSSSQGSYTVVQPTDDSLEQS", "length": 466 }, "evidence": [ { "id": "A0ABI0NYA5", "url": "https://omabrowser.org/oma/group/A0ABI0NYA5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5U2R3-1", "protein_name": "FERM domain-containing protein 8", "gene_name": "Frmd8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGAEGNAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLSSISAHELHRAVREVLQLPDMALEAFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTDASDDDIAMDEPSLQFRRNVFFPKRRELQVHDEEVLRLLYEEAKGNVLTARYPCDLEDCEVLGGLVCRVQLGPYQPGQPAACTVREKLDSFLPAHLCKRGHGLFAAFRGRGAKTGPCEQGLLNAYRQVKEMAGGDSERETTLGSHYRAYLLKCHELPFYGCAFFHGEVDKPTQGFLHRGGRKPVTVAISLEGVHVIDNREKHVLLGLRFQELSWDHTSPEEEEPVLWLEFDGDSEGTPVNKLLRIYSKQAELMSVLIEYCIELSQAAEPALPQESASGPQEAPSPSSAPTQRPKLRRQGSVVCSRIQHLSTIDYVEDGSGIKRVKPKRTTSFFSRQLSSSHGSYTVVQPNDNSPEQG", "length": 466 }, "evidence": [ { "id": "A0ABI0NYA5", "url": "https://omabrowser.org/oma/group/A0ABI0NYA5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BZ67-1", "protein_name": "FERM domain-containing protein 8", "gene_name": "FRMD8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRAVREVLQLPDIALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQLGPYQPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEGVHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPKLRRQGSVVSSRIQHLSTIDYVEDGKGIRRVKPKRTTSFFSRQLSLGQGSYTVVQPGDSLEQG", "length": 464 }, "evidence": [ { "id": "A0ABI0NYA5", "url": "https://omabrowser.org/oma/group/A0ABI0NYA5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYA5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYA5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYA5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYA5" }, { "id": "PS50057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FERM", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 377, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NVZ0-1", "uniprot_ac": "A0ABI0NVZ0", "uniprot_id": "A0ABI0NVZ0_BOVIN", "mass": { "chemical_mass": 58258.0, "monoisotopic_mass": 58258.0 }, "refseq": {}, "gene_names": [ { "name": "AAAS", "type": "recommended", "evidence": [ { "id": "A0ABI0NVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVZ0" } ] } ], "protein_names": [ { "name": "Aladin", "type": "recommended", "evidence": [ { "id": "A0ABI0NVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVZ0/entry#names_and_taxonomy" } ] }, { "name": "Adracalin", "type": "synonym", "evidence": [ { "id": "A0ABI0NVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVZ0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in the normal development of the peripheral and central nervous system. Required for the correct localization of aurora kinase AURKA and the microtubule minus end-binding protein NUMA1 as well as a subset of AURKA targets which ensures proper spindle formation and timely chromosome alignment.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SVE5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVE5#function" }, { "database": "UniProtKB", "id": "ARBA00053972", "url": "https://www.uniprot.org/uniprotkb/ARBA00053972#function" }, { "database": "UniProtKB", "id": "A0ABI0NVZ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVZ0#function" }, { "database": "UniProtKB", "id": "F6QCG0", "url": "https://www.uniprot.org/uniprotkb/F6QCG0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVZ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVZ0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AAAS", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVZ0", "locus": { "chromosome": "5", "start_pos": 26716567, "end_pos": 26700516, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020179", "url": "https://www.ensembl.org/id/ENSBTAG00000020179" } ] } } ], "crossref": [ { "id": "ENSBTAG00000020179", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020179", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F6QCG0", "url": "https://www.orthodb.org/?gene=F6QCG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14494", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14494", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14494:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14494:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25460", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25460", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-159227", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-159227", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-159230", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-159230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-159231", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-159231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-1855170", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-1855196", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855196", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-1855229", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1855229", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-191859", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-191859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-3108214", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3108214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-3232142", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3232142", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-3301854", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3301854", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-3371453", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3371453", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4085377", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4085377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4570464", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4570464", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4615885", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4615885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SVE5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVE5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3V2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3V2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3V2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVZ0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QCG0", "url": "https://www.uniprot.org/uniprotkb/F6QCG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QCG0-1", "url": "https://www.uniprot.org/uniprotkb/F6QCG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RGSVAGVGGGWWGASRSPDWRIGNNLSQWINLPVLNLTKDPLKTPGRLDHGTRTAFIHHREQVWKRCINIWRDVGLFGVLNEIANSEEEVFEWVKTASSWALALCRWASSLHGSLFPHLSLRSEDLIAEFAQVTNWSSCCLRVFAWHPHTNKFAVALLDDSVRVYNANSTIVPSLKHRLQRNVAALAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPSGGRLLSASPVDAAILVWDVSTETCVPLPWFRGGGVTNLLWSPDGSKVLATTPSAVFRVWEAQMWTCERWPTLSGRCQTGCWSPSGNRLLFTVLGEPLIYSLSFPERCGEGKGYVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGNPRVQNGKPVILLFRTRNSPVFELLPCGIIQGELGAQAQLITFHPSFNKGALLSVCWSTGRVTHIPLYFVNARFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPARPHSPHSHFQ", "length": 534, "header": "tr|A0ABI0NVZ0-1|A0ABI0NVZ0_BOVIN Isoform 1 of Aladin OS=Bos taurus OX=9913 GN=AAAS PE=4 SV=1 CANONICAL=A0ABI0NVZ0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SVE5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVZ0/entry#A0AAA9SVE5-1", "sequence": { "sequence": "MKLQIQRKRLRSEDLIAEFAQVTNWSSCCLRVFAWHPHTNKFAVALLDDSVRVYNANSTIVPSLKHRLQRNVAALAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPSGGRLLSASPVDAAILVWDVSTETCVPLPWFRGGGVTNLLWSPDGSKVLATTPSAVFRVWEAQMWTCERWPTLSGRCQTGCWSPSGNRLLFTVLGEPLIYSLSFPERCGEGKGYVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGNPRVQNGKPVILLFRTRNSPVFELLPCGIIQGELGAQAQLITFHPSFNKGALLSVCWSTGRVTHIPLYFVNARFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPARPHSPHSHFQ", "length": 423, "header": "tr|A0AAA9SVE5-1|A0ABI0NVZ0_BOVIN Computationally mapped isoform of Aladin OS=Bos taurus OX=9913 GN=AAAS PE=4 SV=1 CANONICAL=A0ABI0NVZ0-1" }, "locus": { "chromosome": "5", "start_pos": 26716536, "end_pos": 26708586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136012.2", "url": "https://www.ensembl.org/id/ENSBTAT00000136012.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090442.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090442.1" } ] } }, { "isoform_ac": "A0AAA9T3V2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVZ0/entry#A0AAA9T3V2-1", "sequence": { "sequence": "MCSLGLFPPPPPRGQITLYEHNNELVTGSSCESPPPDFRGQWINLPVLNLTKDPLKTPGRLDHGTRTAFIHHREQVWKRCINIWRDVGLFGVLNEIANSEEEVFEWVKTASSWALALCRWASSLHGSLFPHLSLRSEDLIAEFAQVTNCTIVPSLKHRLQRNVAALAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPSGGRLLSASPVDAAILVWDVSTETCVPLPWFRGGGVTNLLWSPDGSKVLATTPSAVFRVWEAQMWTCERWPTLSGRCQTGCWSPSGNRLLFTVLGEPLIYSLSFPERCGEGKGYVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGNPRVQNGKPVILLFRTRNSPVFELLPCGIIQGELGAQAQLITFHPSFNKGALLSVCWSTGRVTHIPLYFVNARFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPARPHSPHSHFQ", "length": 514, "header": "tr|A0AAA9T3V2-1|A0ABI0NVZ0_BOVIN Computationally mapped isoform of Aladin OS=Bos taurus OX=9913 GN=AAAS PE=4 SV=1 CANONICAL=A0ABI0NVZ0-1" }, "locus": { "chromosome": "5", "start_pos": 26716536, "end_pos": 26700620, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135178.2", "url": "https://www.ensembl.org/id/ENSBTAT00000135178.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091172.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091172.1" } ] } }, { "isoform_ac": "A0ABI0NVZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVZ0/entry#A0ABI0NVZ0-1", "sequence": { "sequence": "RGSVAGVGGGWWGASRSPDWRIGNNLSQWINLPVLNLTKDPLKTPGRLDHGTRTAFIHHREQVWKRCINIWRDVGLFGVLNEIANSEEEVFEWVKTASSWALALCRWASSLHGSLFPHLSLRSEDLIAEFAQVTNWSSCCLRVFAWHPHTNKFAVALLDDSVRVYNANSTIVPSLKHRLQRNVAALAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPSGGRLLSASPVDAAILVWDVSTETCVPLPWFRGGGVTNLLWSPDGSKVLATTPSAVFRVWEAQMWTCERWPTLSGRCQTGCWSPSGNRLLFTVLGEPLIYSLSFPERCGEGKGYVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGNPRVQNGKPVILLFRTRNSPVFELLPCGIIQGELGAQAQLITFHPSFNKGALLSVCWSTGRVTHIPLYFVNARFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPARPHSPHSHFQ", "length": 534, "header": "tr|A0ABI0NVZ0-1|A0ABI0NVZ0_BOVIN Isoform 1 of Aladin OS=Bos taurus OX=9913 GN=AAAS PE=4 SV=1 CANONICAL=A0ABI0NVZ0-1" }, "locus": { "chromosome": "5", "start_pos": 26716536, "end_pos": 26700808, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137383.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137383.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105005.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105005.1" } ] } }, { "isoform_ac": "F6QCG0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVZ0/entry#F6QCG0-1", "sequence": { "sequence": "ESASRLPGPGGQGEEGGTFRHGGRCWRWINLPVLNLTKDPLKTPGRLDHGTRTAFIHHREQVWKRCINIWRDVGLFGVLNEIANSEEEVFEWVKTASSWALALCRWASSLHGSLFPHLSLRSEDLIAEFAQVTNWSSCCLRVFAWHPHTNKFAVALLDDSVRVYNANSTIVPSLKHRLQRNVAALAWKPLSASVLAVACQSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPSGGRLLSASPVDAAILVWDVSTETCVPLPWFRGGGVTNLLWSPDGSKVLATTPSAVFRVWEAQMWTCERWPTLSGRCQTGCWSPSGNRLLFTVLGEPLIYSLSFPERCGEGKGYVGGAKSATIVADLSETTIQTPDGEERLGGEAHSMVWDPSGERLAVLMKGNPRVQNGKPVILLFRTRNSPVFELLPCGIIQGELGAQAQLITFHPSFNKGALLSVCWSTGRVTHIPLYFVNARFPRFSPVLGRAQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPARPHSPHSHFQ", "length": 533, "header": "tr|F6QCG0-1|A0ABI0NVZ0_BOVIN Computationally mapped isoform of Aladin OS=Bos taurus OX=9913 GN=AAAS PE=4 SV=2 CANONICAL=A0ABI0NVZ0-1" }, "locus": { "chromosome": "5", "start_pos": 26716536, "end_pos": 26700715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026878.6", "url": "https://www.ensembl.org/id/ENSBTAT00000026878.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026878.5", "url": 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"MGGPRSTNIPGVKKGRRARCSHAHFGDPAAGRTAKELTYPDTRTGAEQRARHAPNPLRLLLALLGPGYLRSPSMLSSSPASCTSPNPDKENPSKKVHWASGRRRTSSTDSESKSQSDPFRPRSRKPSRLTVKYDRGQLQRWVEMEQWVDTQVQELFQDQPTSSEPEIDLEALMELSTEEQKTQLEALLQNCPRPTEPFISELLSQLKKLRRLSRPQK", "length": 217, "header": "tr|F6QQF7-1|A0ABI0NZA8_BOVIN Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 14 OS=Bos taurus OX=9913 GN=PPP1R14D PE=3 SV=2 CANONICAL=A0ABI0NZA8-1" }, "locus": { "chromosome": "10", "start_pos": 36378044, "end_pos": 36355681, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017934.4", "url": "https://www.ensembl.org/id/ENSBTAT00000017934.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017934.4", "url": "https://www.ensembl.org/id/ENSBTAP00000017934.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine phosphatase inhibitor activity", "id": "GO:0004865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004865", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZA8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZA8" } ], "pmid": "" }, { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZA8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZA8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZA8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZA8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZA8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NZD6-1", "uniprot_ac": "A0ABI0NZD6", "uniprot_id": "A0ABI0NZD6_BOVIN", "mass": { "chemical_mass": 303708.0, "monoisotopic_mass": 303708.0 }, "refseq": { "ac": "NP_001179779", "name": "zinc finger protein 292", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179779" }, "gene_names": [ { "name": "ZNF292", "type": "recommended", "evidence": [ { "id": "A0ABI0NZD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6" } ] }, { "name": "ZNF292", "type": "synonym", "evidence": [ { "id": "NP_001179779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179779" } ] } ], "protein_names": [ { "name": "Zinc finger protein 292", "type": "recommended", "evidence": [ { "id": "A0ABI0NZD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 292", "type": "synonym", "evidence": [ { "id": "NP_001179779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179779" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "G3MYM4", "url": "https://www.uniprot.org/uniprotkb/G3MYM4#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0ABI0NVT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVT8#function" }, { "database": "UniProtKB", "id": "A0ABI0NZD6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZD6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF292", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6", "locus": { "chromosome": "9", "start_pos": 62631692, "end_pos": 62656646, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046612", "url": "https://www.ensembl.org/id/ENSBTAG00000046612" } ] } } ], "crossref": [ { "id": "ENSBTAG00000046612", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046612", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "541264", "url": "https://www.ncbi.nlm.nih.gov/gene/541264", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:541264", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541264", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3MYM4", "url": "https://www.orthodb.org/?gene=G3MYM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15507", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15507", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15507:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15507:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25420", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25420", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26218", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26218", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179779", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179779", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NVT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVT8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZD6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZD6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYM4", "url": "https://www.uniprot.org/uniprotkb/G3MYM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYM4-1", "url": "https://www.uniprot.org/uniprotkb/G3MYM4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADEEAEQERLSRGGGGCAAELQRLGERLQELERQLRESRVPAVEAATEYCQQLCQTLLEYAEKWKTSEDPLPLLEVYTVAIQSYVKARPYLTSECENVALVLERLALSCVELLLCLPVELSDKQWEQFQTLVQVAHEKLMENGSCELHFLATLAQETGVWKNPVLCTILSQEPLDKDKVNEFLAFEGPILLDMRIKHLIKTNQLSQATALAKLCSDHPEIGTKGSFKQTYLVCLCTSSPNEKLIEEISEVDCKDALEMICNLESEGDEKSALVLCTAFLSRQLQQGDMYCAWELTLFWSKLQQRVEPSIQVYLERCRQLSLLTKTVYHIFFLIKVINSETEGAGLATCIELCVKALRLESTENTEVKISICKTISCLLPDDLEVKRACQLSEFLIEPTVDAYYAVEMLYNQPDQKYDEENLPIPNSLRCELLLVLKTQWPFDPEFWDWKTLKRQCLALMGEEASIVSSIDELNDSEVYEKVADYQEDSKDTSVNGGIGANSGLRDICDEKQKKREIKQLRERGFISARFRNWQAYMQYCVLCDKEFLGHRIVRHAQKHYKDGIYSCPICAKNFNSKETFVPHVTLHVKQSSKERLAAMKPLRRLGRPPKITATNENQKTNAVAKQEQRPIKKNSLYSTDFIVFNDNDGSDDETDDKDKSYEPEVIPVQKPVPVNEFNCPVTFCKKGFKYFKNLIAHVKGHKDNEDAKRFLEMQSKKVICQYCRRHFVSVTHLNDHLQMHCGSKPYICIQMKCKAGFNSYAELLTHRKEHQVFRAKCMFPKCGRIFSEAYLLYDHEAQHYNTYTCKFTGCGKVYRSQSELEKHLEDHNTPEKVLPPEDQLNSARDSVQPSRVNQSAEGNAEKERSMLPSENSVENTIPADRSGAWDKSKAESPVTKQDQISASELGQADGPLPNGLGNAAPTPLLQASEVAVSIKVSLNQGIEENFGKQENSTVENTGESLVTNLHVPVENACNDLCHTDFQERKEQECFNETQITQNSLVASEALKIDGMTTQNLERQVSNLMTFSVQNQAGFQNSLPTPKFECGGNVKTSSSLYNLPLKTLESITFVPPQPNLSNSLGTPSVPPKAPVQKFSCQVEGCTRTYNSSQSIGKHMKTAHPDQYAAFKMQRKSKRGQKANNLNTPNNGKFVYFLPSQVSSSNNAFFTPQTKASGTPACSAQLQHVSSSIFPAHLASVSAPLLPSVESVMNPSIPSQDKNEQGGGLLCSQMETLSSTTLPAQMEDLTKTVLPLNIDSGSDPFLPLPAESSSVSLFPSPADSGTNSVFSQLENNTSHFSSQIEGNTNSSFLKGGNGENAVFPSQVSVANDFSGAGAQQPGPEKVKKDRGRGPNGKERKPKHNKRAKWPAIIRDGKFICSRCYRAFTNPRSLGGHLSKRSYCKPLDGAEIAQELLQNNGQPSLLASMILSTNAVNLQQPQQSAFSAEACFKDPSFLQLLAAENRSSTFLPNTFPRTAVTSFNSSVSQEGSEIIKQALETAGIPSTFEGADVLSHVPTGCVSDTAQVNTTVMPNPPVPTLLQTVCHPGPLLTDQNGTPNPKTSSIEECRSLPVFPTNDLLLKTVENGLCSSSFPNSSGPSQNFTGSSSRVSVISGPQNTRSSHLNKKGNSASKRRKKVTPPLIAPNTPQNLVTSDLTAMGLIAKSIEIPTTNLHSTVIPNCEPQGLVENLTQKLNNVDNQLFMTDVKENFKTSLESHTVLAPLTLKTENGDSQMMALNSCTPSINSDLQISEDNVIQNFEKTLEIIKSAMNSQILEVKNGSQGIGETSQNAQINYNIQLPSVNTVQNNKLSESSQFSSFIGIMPTKSNIPQSEVLHKEDQIQEILEGLQKLKLENDLSTPAPQCVLINTSVTLTPTPVKSIPNVTVQPISEIISNIQFNDRVNKPFVCQNQGCNYSAMTKDALFKHYGKIHQYTPEMILEIKKNQLKFAPFKCVVPTCTKTFTRNSNLRAHCQLVHHFTTEEMVKLKIKRPYGRKSQSENSSAPRITQVKRQLALTEENKREFQPALELGAMKENTLSNIAVIPEKQLLEKKSPEKTESSSQVIAITSEQCNTNPLTNVQTKGRKVRRHKKEKEERKRKKPVSQSPEFPTRYSPYRPYRCVHQGCFAAFTIQQNLILHYQAVHKSDLPAFSAEVEEESEAGKESEEIETKQTVKEFRCQVSDCSRIFQAITGLIQHYMKLHEMSPEEIESMTASVDVGKFPCDQSECKSSFTTYLNYVVHLEADHGIGARGSKTEEDGIYKCDCEGCDRIYATRSNLLRHIFNKHNDKHKAHLIRPRRLTPGQENISSKANQEKTKSKHRGTKYRSGREGIKMPKTKRKKKNNLENKTAKIVQIEENKPYSLKRGKHVYSIKARNDALSECTSRFVTQYPCMIKGCTSVVTSESNIIRHYKCHKLSKAFTSQHRNLLIVFKRCCSSQLKEASEQEVEKSGVKDSDTSVSESNDNARTAVVPQKEVVKNEKDEVDELTELFITKLINEDNTSVETQPQTSSNVSNDFKENNPCQSEKPKASNLKRVNKEKNVSQNKKRKVEKAEPAPAVELSSIHKEEETAVAIQTTEEHPASFDWSSFKPMGFEVSFLKFLEESAVKQKKNTDKDHPNSGSKKGSHSNSRKNVDKTAVTSGNHTCSCKESETFVQFANPTQLQCSDSVKIVLDKTLKDCTELVLKQLQEMKPTVSLKKLEVRSNDPDVSVMKDISMGKATGRGQY", "length": 2719, "header": "tr|A0ABI0NZD6-1|A0ABI0NZD6_BOVIN Isoform 1 of Zinc finger protein 292 OS=Bos taurus OX=9913 GN=ZNF292 PE=3 SV=1 CANONICAL=A0ABI0NZD6-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NVT8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6/entry#A0ABI0NVT8-1", "sequence": { "sequence": "MDCSLLGLSVHGIFQTLLEYAEKWKTSEDPLPLLEVYTVAIQSYVKARPYLTSECENVALVLERLALSCVELLLCLPVELSDKQWEQFQTLVQVAHEKLMENGSCELHFLATLAQETGVWKNPVLCTILSQEPLDKDKVNEFLAFEGPILLDMRIKHLIKTNQLSQATALAKLCSDHPEIGTKGSFKQTYLVCLCTSSPNEKLIEEISEVDCKDALEMICNLESEGDEKSALVLCTAFLSRQLQQGDMYCAWELTLFWSKLQQRVEPSIQVYLERCRQLSLLTKTVYHIFFLIKVINSETEGAGLATCIELCVKALRLESTENTEVKISICKTISCLLPDDLEVKRACQLSEFLIEPTVDAYYAVEMLYNQPDQKYDEENLPIPNSLRCELLLVLKTQWPFDPEFWDWKTLKRQCLALMGEEASIVSSIDELNDSEVYEKVADYQEDSKDTSVNGGIGANSGLRDICDEKQKKREIKQLRERGFISARFRNWQAYMQYCVLCDKEFLGHRIVRHAQKHYKDGIYSCPICAKNFNSKETFVPHVTLHVKQSSKERLAAMKPLRRLGRPPKITATNENQKTNAVAKQEQRPIKKNSLYSTDFIVFNDNDGSDDETDDKDKSYEPEVIPVQKPVPVNEFNCPVTFCKKGFKYFKNLIAHVKGHKDNEDAKRFLEMQSKKVICQYCRRHFVSVTHLNDHLQMHCGSKPYICIQMKCKAGFNSYAELLTHRKEHQVFRAKCMFPKCGRIFSEAYLLYDHEAQHYNTYTCKFTGCGKVYRSQSELEKHLEDHNTPEKVLPPEDQLNSARDSVQPSRVNQSAEGNAEKERSMLPSENSVENTIPADRSGAWDKSKAESPVTKQDQISASELGQADGPLPNGLGNAAPTPLLQASEVAVSIKVSLNQGIEENFGKQENSTVENTGESLVTNLHVPVENACNDLCHTDFQERKEQECFNETQITQNSLVASEALKIDGMTTQNLERQVSNLMTFSVQNQAGFQNSLPTPKFECGGNVKTSSSLYNLPLKTLESITFVPPQPNLSNSLGTPSVPPKAPVQKFSCQVEGCTRTYNSSQSIGKHMKTAHPDQYAAFKMQRKSKRGQKANNLNTPNNGKFVYFLPSQVSSSNNAFFTPQTKASGTPACSAQLQHVSSSIFPAHLASVSAPLLPSVESVMNPSIPSQDKNEQGGGLLCSQMETLSSTTLPAQMEDLTKTVLPLNIDSGSDPFLPLPAESSSVSLFPSPADSGTNSVFSQLENNTSHFSSQIEGNTNSSFLKGGNGENAVFPSQVSVANDFSGAGAQQPGPEKVKKDRGRGPNGKERKPKHNKRAKWPAIIRDGKFICSRCYRAFTNPRSLGGHLSKRSYCKPLDGAEIAQELLQNNGQPSLLASMILSTNAVNLQQPQQSAFSAEACFKDPSFLQLLAAENRSSTFLPNTFPRTAVTSFNSSVSQEGSEIIKQALETAGIPSTFEGADVLSHVPTGCVSDTAQVNTTVMPNPPVPTLLQTVCHPGPLLTDQNGTPNPKTSSIEECRSLPVFPTNDLLLKTVENGLCSSSFPNSSGPSQNFTGSSSRVSVISGPQNTRSSHLNKKGNSASKRRKKVTPPLIAPNTPQNLVTSDLTAMGLIAKSIEIPTTNLHSTVIPNCEPQGLVENLTQKLNNVDNQLFMTDVKENFKTSLESHTVLAPLTLKTENGDSQMMALNSCTPSINSDLQISEDNVIQNFEKTLEIIKSAMNSQILEVKNGSQGIGETSQNAQINYNIQLPSVNTVQNNKLSESSQFSSFIGIMPTKSNIPQSEVLHKEDQIQEILEGLQKLKLENDLSTPAPQCVLINTSVTLTPTPVKSIPNVTVQPISEIISNIQFNDRVNKPFVCQNQGCNYSAMTKDALFKHYGKIHQYTPEMILEIKKNQLKFAPFKCVVPTCTKTFTRNSNLRAHCQLVHHFTTEEMVKLKIKRPYGRKSQSENSSAPRITQVKRQLALTEENKREFQPALELGAMKENTLSNIAVIPEKQLLEKKSPEKTESSSQVIAITSEQCNTNPLTNVQTKGRKVRRHKKEKEERKRKKPVSQSPEFPTRYSPYRPYRCVHQGCFAAFTIQQNLILHYQAVHKSDLPAFSAEVEEESEAGKESEEIETKQTVKEFRCQVSDCSRIFQAITGLIQHYMKLHEMSPEEIESMTASVDVGKFPCDQSECKSSFTTYLNYVVHLEADHGIGARGSKTEEDGIYKCDCEGCDRIYATRSNLLRHIFNKHNDKHKAHLIRPRRLTPGQENISSKANQEKTKSKHRGTKYRSGREGIKMPKTKRKKKNNLENKTAKIVQIEENKPYSLKRGKHVYSIKARNDALSECTSRFVTQYPCMIKGCTSVVTSESNIIRHYKCHKLSKAFTSQHRNLLIVFKRCCSSQLKEASEQEVEKSGVKDSDTSVSESNDNARTAVVPQKEVVKNEKDEVDELTELFITKLINEDNTSVETQPQTSSNVSNDFKENNPCQSEKPKASNLKRVNKEKNVSQNKKRKVEKAEPAPAVELSSIHKEEETAVAIQTTEEHPASFDWSSFKPMGFEVSFLKFLEESAVKQKKNTDKDHPNSGSKKGSHSNSRKNVDKTAVTSGNHTCSCKESETFVQFANPTQLQCSDSVKIVLDKTLKDCTELVLKQLQEMKPTVSLKKLEVRSNDPDVSVMKDISMGKATGRGQY", "length": 2678, "header": "tr|A0ABI0NVT8-1|A0ABI0NVT8_BOVIN Computationally mapped isoform of Zinc finger protein 292 OS=Bos taurus OX=9913 GN=ZNF292 PE=3 SV=1 CANONICAL=A0ABI0NZD6-1" }, "locus": { "chromosome": "9", "start_pos": 62702008, "end_pos": 62632364, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144999.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144999.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105650.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105650.1" } ] } }, { "isoform_ac": "A0ABI0NZD6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6/entry#A0ABI0NZD6-1", "sequence": { "sequence": "MADEEAEQERLSRGGGGCAAELQRLGERLQELERQLRESRVPAVEAATEYCQQLCQTLLEYAEKWKTSEDPLPLLEVYTVAIQSYVKARPYLTSECENVALVLERLALSCVELLLCLPVELSDKQWEQFQTLVQVAHEKLMENGSCELHFLATLAQETGVWKNPVLCTILSQEPLDKDKVNEFLAFEGPILLDMRIKHLIKTNQLSQATALAKLCSDHPEIGTKGSFKQTYLVCLCTSSPNEKLIEEISEVDCKDALEMICNLESEGDEKSALVLCTAFLSRQLQQGDMYCAWELTLFWSKLQQRVEPSIQVYLERCRQLSLLTKTVYHIFFLIKVINSETEGAGLATCIELCVKALRLESTENTEVKISICKTISCLLPDDLEVKRACQLSEFLIEPTVDAYYAVEMLYNQPDQKYDEENLPIPNSLRCELLLVLKTQWPFDPEFWDWKTLKRQCLALMGEEASIVSSIDELNDSEVYEKVADYQEDSKDTSVNGGIGANSGLRDICDEKQKKREIKQLRERGFISARFRNWQAYMQYCVLCDKEFLGHRIVRHAQKHYKDGIYSCPICAKNFNSKETFVPHVTLHVKQSSKERLAAMKPLRRLGRPPKITATNENQKTNAVAKQEQRPIKKNSLYSTDFIVFNDNDGSDDETDDKDKSYEPEVIPVQKPVPVNEFNCPVTFCKKGFKYFKNLIAHVKGHKDNEDAKRFLEMQSKKVICQYCRRHFVSVTHLNDHLQMHCGSKPYICIQMKCKAGFNSYAELLTHRKEHQVFRAKCMFPKCGRIFSEAYLLYDHEAQHYNTYTCKFTGCGKVYRSQSELEKHLEDHNTPEKVLPPEDQLNSARDSVQPSRVNQSAEGNAEKERSMLPSENSVENTIPADRSGAWDKSKAESPVTKQDQISASELGQADGPLPNGLGNAAPTPLLQASEVAVSIKVSLNQGIEENFGKQENSTVENTGESLVTNLHVPVENACNDLCHTDFQERKEQECFNETQITQNSLVASEALKIDGMTTQNLERQVSNLMTFSVQNQAGFQNSLPTPKFECGGNVKTSSSLYNLPLKTLESITFVPPQPNLSNSLGTPSVPPKAPVQKFSCQVEGCTRTYNSSQSIGKHMKTAHPDQYAAFKMQRKSKRGQKANNLNTPNNGKFVYFLPSQVSSSNNAFFTPQTKASGTPACSAQLQHVSSSIFPAHLASVSAPLLPSVESVMNPSIPSQDKNEQGGGLLCSQMETLSSTTLPAQMEDLTKTVLPLNIDSGSDPFLPLPAESSSVSLFPSPADSGTNSVFSQLENNTSHFSSQIEGNTNSSFLKGGNGENAVFPSQVSVANDFSGAGAQQPGPEKVKKDRGRGPNGKERKPKHNKRAKWPAIIRDGKFICSRCYRAFTNPRSLGGHLSKRSYCKPLDGAEIAQELLQNNGQPSLLASMILSTNAVNLQQPQQSAFSAEACFKDPSFLQLLAAENRSSTFLPNTFPRTAVTSFNSSVSQEGSEIIKQALETAGIPSTFEGADVLSHVPTGCVSDTAQVNTTVMPNPPVPTLLQTVCHPGPLLTDQNGTPNPKTSSIEECRSLPVFPTNDLLLKTVENGLCSSSFPNSSGPSQNFTGSSSRVSVISGPQNTRSSHLNKKGNSASKRRKKVTPPLIAPNTPQNLVTSDLTAMGLIAKSIEIPTTNLHSTVIPNCEPQGLVENLTQKLNNVDNQLFMTDVKENFKTSLESHTVLAPLTLKTENGDSQMMALNSCTPSINSDLQISEDNVIQNFEKTLEIIKSAMNSQILEVKNGSQGIGETSQNAQINYNIQLPSVNTVQNNKLSESSQFSSFIGIMPTKSNIPQSEVLHKEDQIQEILEGLQKLKLENDLSTPAPQCVLINTSVTLTPTPVKSIPNVTVQPISEIISNIQFNDRVNKPFVCQNQGCNYSAMTKDALFKHYGKIHQYTPEMILEIKKNQLKFAPFKCVVPTCTKTFTRNSNLRAHCQLVHHFTTEEMVKLKIKRPYGRKSQSENSSAPRITQVKRQLALTEENKREFQPALELGAMKENTLSNIAVIPEKQLLEKKSPEKTESSSQVIAITSEQCNTNPLTNVQTKGRKVRRHKKEKEERKRKKPVSQSPEFPTRYSPYRPYRCVHQGCFAAFTIQQNLILHYQAVHKSDLPAFSAEVEEESEAGKESEEIETKQTVKEFRCQVSDCSRIFQAITGLIQHYMKLHEMSPEEIESMTASVDVGKFPCDQSECKSSFTTYLNYVVHLEADHGIGARGSKTEEDGIYKCDCEGCDRIYATRSNLLRHIFNKHNDKHKAHLIRPRRLTPGQENISSKANQEKTKSKHRGTKYRSGREGIKMPKTKRKKKNNLENKTAKIVQIEENKPYSLKRGKHVYSIKARNDALSECTSRFVTQYPCMIKGCTSVVTSESNIIRHYKCHKLSKAFTSQHRNLLIVFKRCCSSQLKEASEQEVEKSGVKDSDTSVSESNDNARTAVVPQKEVVKNEKDEVDELTELFITKLINEDNTSVETQPQTSSNVSNDFKENNPCQSEKPKASNLKRVNKEKNVSQNKKRKVEKAEPAPAVELSSIHKEEETAVAIQTTEEHPASFDWSSFKPMGFEVSFLKFLEESAVKQKKNTDKDHPNSGSKKGSHSNSRKNVDKTAVTSGNHTCSCKESETFVQFANPTQLQCSDSVKIVLDKTLKDCTELVLKQLQEMKPTVSLKKLEVRSNDPDVSVMKDISMGKATGRGQY", "length": 2719, "header": "tr|A0ABI0NZD6-1|A0ABI0NZD6_BOVIN Isoform 1 of Zinc finger protein 292 OS=Bos taurus OX=9913 GN=ZNF292 PE=3 SV=1 CANONICAL=A0ABI0NZD6-1" }, "locus": { "chromosome": "9", "start_pos": 62725418, "end_pos": 62632364, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150622.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150622.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105877.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105877.1" } ] } }, { "isoform_ac": "G3MYM4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6/entry#G3MYM4-1", "sequence": { "sequence": "MNEFLAFEGPILLDMRIKHLIKTNQLSQATALAKLCSDHPEIGTKGSFKQTYLVCLCTSSPNEKLIEEISEVDCKDALEMICNLESEGDEKSALVLCTAFLSRQLQQGDMYCAWELTLFWSKLQQRVEPSIQVYLERCRQLSLLTKTVYHIFFLIKVINSETEGAGLATCIELCVKALRLESTENTEVKISICKTISCLLPDDLEVKRACQLSEFLIEPTVDAYYAVEMLYNQPDQKYDEENLPIPNSLRCELLLVLKTQWPFDPEFWDWKTLKRQCLALMGEEASIVSSIDELNDSEVYEKVADYQEDSKDTSVNGGIGANSGLRDICDEKQKKREIKQLRERGFISARFRNWQAYMQYCVLCDKEFLGHRIVRHAQKHYKDGIYSCPICAKNFNSKETFVPHVTLHVKQSSKERLAAMKPLRRLGRPPKITATNENQKTNAVAKQEQRPIKKNSLYSTDFIVFNDNDGSDDETDDKDKSYEPEVIPVQKPVPVNEFNCPVTFCKKGFKYFKNLIAHVKGHKDNEDAKRFLEMQSKKVICQYCRRHFVSVTHLNDHLQMHCGSKPYICIQMKCKAGFNSYAELLTHRKEHQVFRAKCMFPKCGRIFSEAYLLYDHEAQHYNTYTCKFTGCGKVYRSQSELEKHLEDHNTPEKVLPPEDQLNSARDSVQPSRVNQSAEGNAEKERSMLPSENSVENTIPADRSGAWDKSKAESPVTKQDQISASELGQADGPLPNGLGNAAPTPLLQASEVAVSIKVSLNQGIEENFGKQENSTVENTGESLVTNLHVPVENACNDLCHTDFQERKEQECFNETQITQNSLVASEALKIDGMTTQNLERQVSNLMTFSVQNQAGFQNSLPTPKFECGGNVKTSSSLYNLPLKTLESITFVPPQPNLSNSLGTPSVPPKAPVQKFSCQVEGCTRTYNSSQSIGKHMKTAHPDQYAAFKMQRKSKRGQKANNLNTPNNGKFVYFLPSQVSSSNNAFFTPQTKASGTPACSAQLQHVSSSIFPAHLASVSAPLLPSVESVMNPSIPSQDKNEQGGGLLCSQMETLSSTTLPAQMEDLTKTVLPLNIDSGSDPFLPLPAESSSVSLFPSPADSGTNSVFSQLENNTSHFSSQIEGNTNSSFLKGGNGENAVFPSQVSVANDFSGAGAQQPGPEKVKKDRGRGPNGKERKPKHNKRAKWPAIIRDGKFICSRCYRAFTNPRSLGGHLSKRSYCKPLDGAEIAQELLQNNGQPSLLASMILSTNAVNLQQPQQSAFSAEACFKDPSFLQLLAAENRSSTFLPNTFPRTAVTSFNSSVSQEGSEIIKQALETAGIPSTFEGADVLSHVPTGCVSDTAQVNTTVMPNPPVPTLLQTVCHPGPLLTDQNGTPNPKTSSIEECRSLPVFPTNDLLLKTVENGLCSSSFPNSSGPSQNFTGSSSRVSVISGPQNTRSSHLNKKGNSASKRRKKVTPPLIAPNTPQNLVTSDLTAMGLIAKSIEIPTTNLHSTVIPNCEPQGLVENLTQKLNNVDNQLFMTDVKENFKTSLESHTVLAPLTLKTENGDSQMMALNSCTPSINSDLQISEDNVIQNFEKTLEIIKSAMNSQILEVKNGSQGIGETSQNAQINYNIQLPSVNTVQNNKLSESSQFSSFIGIMPTKSNIPQSEVLHKEDQIQEILEGLQKLKLENDLSTPAPQCVLINTSVTLTPTPVKSIPNVTVQPISEIISNIQFNDRVNKPFVCQNQGCNYSAMTKDALFKHYGKIHQYTPEMILEIKKNQLKFAPFKCVVPTCTKTFTRNSNLRAHCQLVHHFTTEEMVKLKIKRPYGRKSQSENSSAPRITQVKRQLALTEENKREFQPALELGAMKENTLSNIAVIPEKQLLEKKSPEKTESSSQVIAITSEQCNTNPLTNVQTKGRKVRRHKKEKEERKRKKPVSQSPEFPTRYSPYRPYRCVHQGCFAAFTIQQNLILHYQAVHKSDLPAFSAEVEEESEAGKESEEIETKQTVKEFRCQVSDCSRIFQAITGLIQHYMKLHEMSPEEIESMTASVDVGKFPCDQSECKSSFTTYLNYVVHLEADHGIGARGSKTEEDGIYKCDCEGCDRIYATRSNLLRHIFNKHNDKHKAHLIRPRRLTPGQENISSKANQEKTKSKHRGTKYRSGREGIKMPKTKRKKKNNLENKTAKIVQIEENKPYSLKRGKHVYSIKARNDALSECTSRFVTQYPCMIKGCTSVVTSESNIIRHYKCHKLSKAFTSQHRNLLIVFKRCCSSQLKEASEQEVEKSGVKDSDTSVSESNDNARTAVVPQKEVVKNEKDEVDELTELFITKLINEDNTSVETQPQTSSNVSNDFKENNPCQSEKPKASNLKRVNKEKNVSQNKKRKVEKAEPAPAVELSSIHKEEETAVAIQTTEEHPASFDWSSFKPMGFEVSFLKFLEESAVKQKKNTDKDHPNSGSKKGSHSNSRKNVDKTAVTSGNHTCSCKESETFVQFANPTQLQCSDSVKIVLDKTLKDCTELVLKQLQEMKPTVSLKKLEVRSNDPDVSVMKDISMGKATGRGQY", "length": 2540, "header": "tr|G3MYM4-1|A0ABI0NZD6_BOVIN Computationally mapped isoform of Zinc finger protein 292 OS=Bos taurus OX=9913 GN=ZNF292 PE=3 SV=2 CANONICAL=A0ABI0NZD6-1" }, "locus": { "chromosome": "9", "start_pos": 62656523, "end_pos": 62632364, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064161.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064161.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054660.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054660.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1081, "start_aa": "Thr", "end_pos": 1081, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1081", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1870, "start_aa": "Thr", "end_pos": 1870, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1870", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:541264", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541264", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZD6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZD6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZD6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZD6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZD6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZD6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZD6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1074, "end_pos": 1076, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1105, "end_pos": 1107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1289, "end_pos": 1291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1290, "end_pos": 1292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1303, "end_pos": 1305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1458, "end_pos": 1460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1477, "end_pos": 1479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1522, "end_pos": 1524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1549, "end_pos": 1551, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1589, "end_pos": 1591, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1596, "end_pos": 1598, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1683, "end_pos": 1685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1773, "end_pos": 1775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1862, "end_pos": 1864, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1877, "end_pos": 1879, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1908, "end_pos": 1910, "annotation": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21296", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21296", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23381", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23381", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-111458", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111458", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-111459", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111459", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9627069", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9627069", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015326596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326596", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFL7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZV9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZZ2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7I8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S702", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S702", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S702-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S702-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NX39", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NX39-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MUW4", "url": "https://www.uniprot.org/uniprotkb/F1MUW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MUW4-1", "url": "https://www.uniprot.org/uniprotkb/F1MUW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAKARNCLLQHREALERDIKTSYIMDHMISNGVLTVSEEEKVKNEPTQRQRAAMLIKMILKKDNHSYISFYNALLHEGYKDLAALLHGGIPVISSSDGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSFLEDCFPGGVHWVSVGKQDKSGLLMKLQNLCARLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDIWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKYVVPVESGLGKEKGLEILSLFVNMKKADLPEQAHSIIQECKGSPLVVSLIGALLRDFPNRWEYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDLETEEVEDILQEFVNKSLLFCDRNGKSFLYYLHDLQVDFLAEKNRSQLQDLHKKMVTQFQRHHQLYSLSPDQEDCMYWYSFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDGIDCENFQEFLSLNGHLLGRQPFPNIVQLGLCELETSEVYRQAKLQAKQEVDNGMLYLEWVNKKNMKNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSADDKFIATCSVDKKVKIWNSMTGELVRIYDEHSEQVNCCHFTNNSNHLLLATGSNDYFLKLWDLNQEECRNTMFGHTNSVSHCRFSPDDQVLASCSADGTLKLWDVKSANERKSINVKQFFLNSEEPQEDLEVIVKCCSWSADGAKIMVAAKNKVFLFDIHSSGLLAEMHMGHHSAVQYCDFSPHNHLAVVALSQYCVELWSMDSGLKVADCRGHLSWVHCVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSATVLKQEIDVVFQENEVTVLAVDNIRRLQLINGNTGQIDYLTEAQVSCCCLSPHLQYLAFGGEDGAIQILELLNNRIFQSRNGHKTTVRHIQFTADGKTLISSSDDSAVQIWNWQSEDPFFLQAHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITRRIEKDFVCHQDTVLSCDISSDATKFSSTSADKTAKIWSFELLSPLHELRGHKGCVRCSSFSVNNTLLATGDDNGEIRIWNVSNGELLHLCAPISVEEGAATHGGWVTDLCFSPDTKMLVSAGGYLKWWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILKILE", "length": 1249, "header": "tr|A0ABI0NX39-1|A0ABI0NX39_BOVIN Isoform 1 of Apoptotic protease-activating factor 1 OS=Bos taurus OX=9913 GN=APAF1 PE=4 SV=1 CANONICAL=A0ABI0NX39-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LFL7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX39/entry#A0A3Q1LFL7-1", "sequence": { "sequence": "MDAKARNCLLQHREALERDIKTSYIMDHMISNGVLTVSEEEKVKNEPTQRQRAAMLIKMILKKDNHSYISFYNALLHEGYKDLAALLHGGIPVISSSDGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSFLEDCFPGGVHWVSVGKQDKSGLLMKLQNLCARLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDIWDPWVLKAFDNQCQILLTTRDKSVTDSVMGSPLVVSLIGALLRDFPNRWEYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDLETEEVEDILQEFVNKSLLFCDRNGKSFLYYLHDLQVDFLAEKNRSQLQDLHKKMVTQFQRHHQLYSLSPDQEDCMYWYSFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDGIDCENFQEFLSLNGHLLGRQPFPNIVQLGLCELETSEVYRQAKLQAKQEVDNGMLYLEWVNKKNMKNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSADDKFIATCSVDKKVKIWNSMTGELVRIYDEHSEQVNCCHFTNNSNHLLLATGSNDYFLKLWDLNQEECRNTMFGHTNSVSHCRFSPDDQVLASCSADGTLKLWDVKSANERKSINVKQFFLNSEEPQEDLEVIVKCCSWSADGAKIMVAAKNKVFLFDIHSSGLLAEMHMGHHSAVQYCDFSPHNHLAVVALSQYCVELWSMDSGLKVADCRGHLSWVHCVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSATVLKQEIDVVFQENEVTVLAVDNIRRLQLINGNTGQIDYLTEAQVSCCCLSPHLQYLAFGGEDGAIQILELLNNRIFQSRNGHKTTVRHIQFTADGKTLISSSDDSAVQIWNWQSEDPFFLQAHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITRRIEKDFVCHQDTVLSCDISSDATKFSSTSADKTAKIWSFELLSPLHELRGHKGCVRCSSFSVNNTLLATGDDNGEIRIWNVSNGELLHLCAPISVEEGAATHGGWVTDLCFSPDTKMLVSAGGYLKWWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILKILE", "length": 1205, "header": "tr|A0A3Q1LFL7-1|A0ABI0NX39_BOVIN Computationally mapped isoform of Apoptotic protease-activating factor 1 OS=Bos taurus OX=9913 GN=APAF1 PE=4 SV=2 CANONICAL=A0ABI0NX39-1" }, "locus": { "chromosome": "5", "start_pos": 62867063, "end_pos": 62784947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081927.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081927.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056997.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056997.2" } ] } }, { "isoform_ac": "A0A3Q1LZV9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX39/entry#A0A3Q1LZV9-1", "sequence": { "sequence": "MDAKARNCLLQHREALERDIKTSYIMDHMISNGVLTVSEEEKVKNEPTQRQRAAMLIKMILKKDNHSYISFYNALLHEGYKDLAALLHGGIPVISSSDGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSFLEDCFPGGVHWVSVGKQDKSGLLMKLQNLCARLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDIWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKYVVPVESGLGKEKGLEILSLFVNMKKADLPEQAHSIIQECKGSPLVVSLIGALLRDFPNRWEYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDLETEEVEDILQEFVNKSLLFCDRNGKSFLYYLHDLQVDFLAEKNRSQLQELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDGIDCENFQEFLSLNGHLLGRQPFPNIVQLGLCELETSEVYRQAKLQAKQEVDNGMLYLEWVNKKNMKNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSADDKFIATCSVDKKVKIWNSMTGELVRIYDEHSEQVNCCHFTNNSNHLLLATGSNDYFLKLWDLNQEECRNTMFGHTNSVSHCRFSPDDQVLASCSADGTLKLWDVKSANERKSINVKQFFLNSEEPQEDLEVIVKCCSWSADGAKIMVAAKNKVFLFDIHSSGLLAEMHMGHHSAVQYCDFSPHNHLAVVALSQYCVELWSMDSGLKVADCRGHLSWVHCVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSATVLKQEIDVVFQENEVTVLAVDNIRRLQLINGNTGQIDYLTEAQVSCCCLSPHLQYLAFGGEDGAIQILELLNNRIFQSRNGHKTTVRHIQFTADGKTLISSSDDSAVQIWNWQSEDPFFLQAHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITRRIEKDFVCHQDTVLSCDISSDATKFSSTSADKTAKIWSFELLSPLHELRGHKGCVRCSSFSVNNTLLATGDDNGEIRIWNVSNGELLHLCAPISVEEGAATHGGWVTDLCFSPDTKMLVSAGGYLKWWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILKILE", "length": 1205, "header": "tr|A0A3Q1LZV9-1|A0ABI0NX39_BOVIN Computationally mapped isoform of Apoptotic protease-activating factor 1 OS=Bos taurus OX=9913 GN=APAF1 PE=4 SV=1 CANONICAL=A0ABI0NX39-1" }, "locus": { "chromosome": "5", "start_pos": 62867063, "end_pos": 62784947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074258.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074258.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062883.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062883.2" } ] } }, { "isoform_ac": "A0A3Q1LZZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX39/entry#A0A3Q1LZZ2-1", "sequence": { "sequence": "MDAKARNCLLQHREALERDIKTSYIMDHMISNGVLTVSEEEKVKNEPTQRQRAAMLIKMILKKDNHSYISFYNALLHEGYKDLAALLHGGIPVISSSDGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSFLEDCFPGGVHWVSVGKQDKSGLLMKLQNLCARLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDIWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKYVVPVESGLGKEKGLEILSLFVNMKKADLPEQAHSIIQECKGSPLVVSLIGALLRDFPNRWEYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDLETEEVEDILQEFVNKSLLFCDRNGKSFLYYLHDLQVDFLAEKNRSQLQDLHKKMVTQFQRHHQLYSLSPDQEDCMYWYSFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDGIDCENFQEFLSLNGHLLGRQPFPNIVQLGLCELETSEVYRQAKLQAKQEVDNGMLYLEWVNKKNMKNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSADDKFIATCSVDKKVKIWNSMTGELVRIYDEHSEQVNCCHFTNNSNHLLLATGSNDYFLKLWDLNQEECRNTMFGHTNSVSHCRFSPDDQVLASCSADGTLKLWDVKSANERKSINVKQFFLNSEEPQEDLEVIVKCCSWSADGAKIMVAAKNKVFLFDIHSSGLLAEMHMGHHSAVQYCDFSPHNHLAVVALSQYCVELWSMDSGLKVADCRGHLSWVHCVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSATVLKQEIDVVFQENEVTVLAVDNIRRLQLINGNTGQIDYLTEAQVSCCCLSPHLQYLAFGGEDGAIQILELLNNRIFQSRNGHKTTVRHIQFTADGKTLISSSDDSAVQIWNWQSEDPFFLQAHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITRRIEKDFVCHQDTVLSCDISSDATKFSSTSADKTAKIWSFELLSPLHELRGHKGCVRCSSFSVNNTLLATGDDNGEIRIWNVSNGELLHLCAPISVEEGAATHGGWVTDLCFSPDTKMLVSAGGYLKWWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLDEWHCQCCSLSEFQENSLVFYTILEESL", "length": 1267, "header": "tr|A0A3Q1LZZ2-1|A0ABI0NX39_BOVIN Computationally mapped isoform of Apoptotic protease-activating factor 1 OS=Bos taurus OX=9913 GN=APAF1 PE=4 SV=2 CANONICAL=A0ABI0NX39-1" }, "locus": { "chromosome": "5", "start_pos": 62868057, "end_pos": 62784947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085731.3", "url": "https://www.ensembl.org/id/ENSBTAT00000085731.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061307.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061307.2" } ] } }, { "isoform_ac": "A0A3Q1M7I8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX39/entry#A0A3Q1M7I8-1", "sequence": { "sequence": "MDAKARNCLLQHREALERDIKTSYIMDHMISNGVLTVSEEEKVKNEPTQRQRAAMLIKMILKKDNHSYISFYNALLHEGYKDLAALLHGGIPVISSSDGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSFLEDCFPGGVHWVSVGKQDKSGLLMKLQNLCARLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDIWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKYVVPVESGLGKEKGLEILSLFVNMKKADLPEQAHSIIQECKGSPLVVSLIGALLRDFPNRWEYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDLETEEVEDILQEFVNKSLLFCDRNGKSFLYYLHDLQVDFLAEKNRSQLQDLHKKMVTQFQRHHQLYSLSPDQEDCMYWYSFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDGIDCENFQEFLSLNGHLLGRQPFPNIVQLGLCELETSEVYRQAKLQAKQEVDNGMLYLEWVNKKNMKNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSADDKFIATCSVDKKVKIWNSMTGELVRIYDEHSEQVNCCHFTNNSNHLLLATGSNDYFLKLWDLNQEECRNTMFGHTNSVSHCRFSPDDQVLASCSADGTLKLWDVKSANERKSINVKQFFLNSEEPQEDLEVIVKCCSWSADGAKIMVAAKNKVFLWSMDSGLKVADCRGHLSWVHCVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSATVLKQEIDVVFQENEVTVLAVDNIRRLQLINGNTGQIDYLTEAQVSCCCLSPHLQYLAFGGEDGAIQILELLNNRIFQSRNGHKTTVRHIQFTADGKTLISSSDDSAVQIWNWQSEDPFFLQAHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITRRIEKDFVCHQDTVLSCDISSDATKFSSTSADKTAKIWNVSNGELLHLCAPISVEEGAATHGGWVTDLCFSPDTKMLVSAGGYLKWWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILKILE", "length": 1164, "header": "tr|A0A3Q1M7I8-1|A0ABI0NX39_BOVIN Computationally mapped isoform of Apoptotic protease-activating factor 1 OS=Bos taurus OX=9913 GN=APAF1 PE=4 SV=2 CANONICAL=A0ABI0NX39-1" }, "locus": { "chromosome": "5", "start_pos": 62867063, "end_pos": 62784947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084580.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084580.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069788.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069788.2" } ] } }, { "isoform_ac": "A0AAA9S702-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX39/entry#A0AAA9S702-1", "sequence": { "sequence": "MDAKARNCLLQHREALERDIKTSYIMDHMISNGVLTVSEEEKVKNEPTQRQRAAMLIKMILKKDNHSYISFYNALLHEGYKDLAALLHGGIPVISSSDGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSFLEDCFPGGVHWVSVGKQDKSGLLMKLQNLCARLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDIWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKYVVPVESGLGKEKGLEILSLFVNMKKADLPEQAHSIIQECKVVECCHWGILTDLLHKRNQS", "length": 338, "header": "tr|A0AAA9S702-1|A0ABI0NX39_BOVIN Computationally mapped isoform of Apoptotic protease-activating factor 1 OS=Bos taurus OX=9913 GN=APAF1 PE=4 SV=1 CANONICAL=A0ABI0NX39-1" }, "locus": { "chromosome": "5", "start_pos": 62866978, "end_pos": 62784947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133130.2", "url": "https://www.ensembl.org/id/ENSBTAT00000133130.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079080.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079080.1" } ] } }, { "isoform_ac": "A0ABI0NX39-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX39/entry#A0ABI0NX39-1", "sequence": { "sequence": "MDAKARNCLLQHREALERDIKTSYIMDHMISNGVLTVSEEEKVKNEPTQRQRAAMLIKMILKKDNHSYISFYNALLHEGYKDLAALLHGGIPVISSSDGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSFLEDCFPGGVHWVSVGKQDKSGLLMKLQNLCARLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDIWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKYVVPVESGLGKEKGLEILSLFVNMKKADLPEQAHSIIQECKGSPLVVSLIGALLRDFPNRWEYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDLETEEVEDILQEFVNKSLLFCDRNGKSFLYYLHDLQVDFLAEKNRSQLQDLHKKMVTQFQRHHQLYSLSPDQEDCMYWYSFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDGIDCENFQEFLSLNGHLLGRQPFPNIVQLGLCELETSEVYRQAKLQAKQEVDNGMLYLEWVNKKNMKNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSADDKFIATCSVDKKVKIWNSMTGELVRIYDEHSEQVNCCHFTNNSNHLLLATGSNDYFLKLWDLNQEECRNTMFGHTNSVSHCRFSPDDQVLASCSADGTLKLWDVKSANERKSINVKQFFLNSEEPQEDLEVIVKCCSWSADGAKIMVAAKNKVFLFDIHSSGLLAEMHMGHHSAVQYCDFSPHNHLAVVALSQYCVELWSMDSGLKVADCRGHLSWVHCVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSATVLKQEIDVVFQENEVTVLAVDNIRRLQLINGNTGQIDYLTEAQVSCCCLSPHLQYLAFGGEDGAIQILELLNNRIFQSRNGHKTTVRHIQFTADGKTLISSSDDSAVQIWNWQSEDPFFLQAHQETVKDFRLLKNSRLLSWSFDGTVKVWNIITRRIEKDFVCHQDTVLSCDISSDATKFSSTSADKTAKIWSFELLSPLHELRGHKGCVRCSSFSVNNTLLATGDDNGEIRIWNVSNGELLHLCAPISVEEGAATHGGWVTDLCFSPDTKMLVSAGGYLKWWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILKILE", "length": 1249, "header": "tr|A0ABI0NX39-1|A0ABI0NX39_BOVIN Isoform 1 of Apoptotic protease-activating factor 1 OS=Bos taurus OX=9913 GN=APAF1 PE=4 SV=1 CANONICAL=A0ABI0NX39-1" }, "locus": { "chromosome": "5", "start_pos": 62867063, "end_pos": 62784947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149884.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149884.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106369.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106369.1" } ] } }, { "isoform_ac": "F1MUW4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX39/entry#F1MUW4-1", "sequence": { "sequence": 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"database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13449", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13449", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13449:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13449:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21883", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21883", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3238698", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3238698", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179580", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179580", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LTV1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LTV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVX1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGH5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SG68", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SG68-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SW08", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SW08-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NY61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NY61-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDN1", "url": "https://www.uniprot.org/uniprotkb/E1BDN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDN1-1", "url": "https://www.uniprot.org/uniprotkb/E1BDN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAIIENMSTKKLCIVGGILLVFQIIAFLVGGLIAPGPTTAVSYMSVKCVDVRKNHHKAKWLMPWGPNQCDKIRDIEEAIPREIEANDIVFSVHIPLPSMEMSPWFQFMLFILQLDIAFKLNNQIRENAEVSMDVSLAYRDDMFAEWTEMAHERVPRKLKCTFTSPKTLEHEGRYYECDVLPFMEIGSVAHKYYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVWFAMKTFLTPSIFIIMVWYWRRITMMSRPPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQHERNHIAGYWKQVGPIAVGSFCLFIFDMCERGVQLTNPFYSIWTTDVGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKVRRLHYEGLIFRFKFLMLITLACAAMTVIFFIVSQVTEGHWKWGGVTVQVNSAFFTGIYGMWNLYVFALMFLYAPSHKNYGEDQSNGDLGVHSGEELQLTTTITHVDGPTEIYKLTRKEAQE", "length": 541, "header": "tr|A0ABI0NY61-1|A0ABI0NY61_BOVIN Isoform 1 of Wnt ligand secretion mediator OS=Bos taurus OX=9913 GN=WLS PE=3 SV=1 CANONICAL=A0ABI0NY61-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LTV1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61/entry#A0A3Q1LTV1-1", "sequence": { "sequence": "MAGAIIENMSTKKLCIVGGILLVFQIIAFLVGGLIGPTTAVSYMSVKCVDVRKNHHKAKWLMPWGPNQCDKIRDIEEAIPREIEANDIVFSVHIPLPSMEMSPWFQFMLFILQLDIAFKLNNQIRENAEVSMDVSLAYRDDMFAEWTEMAHERVPRKLKCTFTSPKTLEHEGRYYECDVLPFMEIGSVAHKYYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVWFAMKTFLTPSIFIIMVWYWRRITMMSRPPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQHERNHIAGYWKQVGPIAVGSFCLFIFDMCERGVQLTNPFYSIWTTDVGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKVRRLHYEGLIFRFKFLMLITLACAAMTVIFFIVSQVTEGHWKWGGVTVQVNSAFFTGIYGMWNLYVFALMFLYAPSHKNYGEDQSNGMQLPYKVREDCTSFVSELYQELSPTLEYSFFDDNSTSGI", "length": 543, "header": "tr|A0A3Q1LTV1-1|A0ABI0NY61_BOVIN Computationally mapped isoform of Wnt ligand secretion mediator OS=Bos taurus OX=9913 GN=WLS PE=3 SV=2 CANONICAL=A0ABI0NY61-1" }, "locus": { "chromosome": "3", "start_pos": 77215038, "end_pos": 77071098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071206.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071206.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060526.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060526.2" } ] } }, { "isoform_ac": "A0A3Q1LVX1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61/entry#A0A3Q1LVX1-1", "sequence": { "sequence": "MAGAIIENMSTKKLCIVGGILLVFQIIAFLVGGLIAPGPTTAVSYMSVKCVDVRKNHHKAKWLMPWGPNQCDKIRDIEEAIPREIEANDIVFSVHIPLPSMEMSPWFQFMLFILQLDIAFKLNNQIRENAEVSMDVSLAYRDDMFAEWTEMAHERVPRKLKCTFTSPKTLEHEGRYYECDVLPFMEIGSVAHKYYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVWFAMKTFLTPSIFIIMVWYWRRITMMSRPPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQHERNHIAGYWKQVGPIAVGSFCLFIFDMCERGVQLTNPFYSIWTTDVGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKVRRLHYEGLIFRFKFLMLITLACAAMTVIFFIVSQVTEGHWKWGGVTVQVNSAFFTGIYGMWNLYVFALMFLYAPSHKNYGEDQSNAFKVQSQ", "length": 512, "header": "tr|A0A3Q1LVX1-1|A0ABI0NY61_BOVIN Computationally mapped isoform of Wnt ligand secretion mediator OS=Bos taurus OX=9913 GN=WLS PE=3 SV=1 CANONICAL=A0ABI0NY61-1" }, "locus": { "chromosome": "3", "start_pos": 77178881, "end_pos": 77071098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073914.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073914.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059504.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059504.1" } ] } }, { "isoform_ac": "A0A3Q1MGH5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61/entry#A0A3Q1MGH5-1", "sequence": { "sequence": "MAGAIIENMSTKKLCIVGGILLVFQIIAFLVGGLIGENAEVSMDVSLAYRDDMFAEWTEMAHERVPRKLKCTFTSPKTLEHEGRYYECDVLPFMEIGSVAHKYYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVWFAMKTFLTPSIFIIMVWYWRRITMMSRPPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQHERNHIAGYWKQVGPIAVGSFCLFIFDMCERGVQLTNPFYSIWTTDVGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKVRRLHYEGLIFRFKFLMLITLACAAMTVIFFIVSQVTEGHWKWGGVTVQVNSAFFTGIYGMWNLYVFALMFLYAPSHKNYGEDQSNGDLGVHSGEELQLTTTITHVDGPTEIYKLTRKEAQE", "length": 450, "header": "tr|A0A3Q1MGH5-1|A0ABI0NY61_BOVIN Computationally mapped isoform of Wnt ligand secretion mediator OS=Bos taurus OX=9913 GN=WLS PE=3 SV=2 CANONICAL=A0ABI0NY61-1" }, "locus": { "chromosome": "3", "start_pos": 77186493, "end_pos": 77071098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077814.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077814.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070284.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070284.2" } ] } }, { "isoform_ac": "A0A3Q1MNC2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61/entry#A0A3Q1MNC2-1", "sequence": { "sequence": "MAGAIIENMSTKKLCIVGGILLVFQIIAFLVGGLIAPGPTTAVSYMSVKCVDVRKNHHKAKWLMPWGPNQCDKIRDIEEAIPREIEANDIVFSVHIPLPSMEMSPWFQFMLFILQLDIAFKLNNQIRENAEVSMDVSLAYRDDMFAEWTEMAHERVPRKLKCTFTSPKTLEHEGRYYECDVLPFMEIGSVAHKYYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVWFAMKTFLTPSIFIIMVWYWRRITMMSRPPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQHERNHIAGYWKQVGPIAVGSFCLFIFDMCERGVQLTNPFYSIWTTDVGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKVRRLHYEISETKQEPQIHQQHIGEASQEDRVNLSLWPSCHSRGTTLLPAISCPLSPLLSLFCFLSLSPFRLSLSPPLHLRGAALLCWKWGKRDLPGIFKPCHLVFHFLLIYMHRARQGKSPAVLTGWESSHMMFALWVYLIHHISNC", "length": 566, "header": "tr|A0A3Q1MNC2-1|A0ABI0NY61_BOVIN Computationally mapped isoform of Wnt ligand secretion mediator OS=Bos taurus OX=9913 GN=WLS PE=3 SV=1 CANONICAL=A0ABI0NY61-1" }, "locus": { "chromosome": "3", "start_pos": 77161254, "end_pos": 77071098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083860.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083860.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072750.1", "url": "https://www.ensembl.org/id/ENSBTAP00000072750.1" } ] } }, { "isoform_ac": "A0AAA9SG68-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61/entry#A0AAA9SG68-1", "sequence": { "sequence": "MAGAIIENMSTKKLCIVGGILLVFQIIAFLVGGLIAPGPTTAVSYMSVKCVDVRKNHHKAKWLMPWGPNQCDKIRDIEEAIPREIEANDIVFSVHIPLPSMEMSPWFQFMLFILQLDIAFKLNNQIRENAEVSMDVSLAYRDDMFAEWTEMAHERVPRKLKCTFTSPKTLEHEGRYYECDVLPFMEIGSVAHKYYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVWFAMKTFLTPSIFIIMVWYWRRITMMSRPPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQHERNHIAGYWKQVGPIAVGSFCLFIFDMCERGVQLTNPFYSIWTTDVGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKVRRLHYEGLIFRFKFLMLITLACAAMTVIFFIVSQPTRLLCPWGFSRQEYWSGLPSPLPGDLRNPGFLWASLVAQLVKNPPAMGKTPVRSLGWEDPLEKGKATHSSILAWRIPWTV", "length": 535, "header": "tr|A0AAA9SG68-1|A0ABI0NY61_BOVIN Computationally mapped isoform of Wnt ligand secretion mediator OS=Bos taurus OX=9913 GN=WLS PE=3 SV=1 CANONICAL=A0ABI0NY61-1" }, "locus": { "chromosome": "3", "start_pos": 77173689, "end_pos": 77071098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125268.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125268.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082869.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082869.1" } ] } }, { "isoform_ac": "A0AAA9SW08-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61/entry#A0AAA9SW08-1", "sequence": { "sequence": "MFGNGEERSFRNFAPGPTTAVSYMSVKCVDVRKNHHKAKWLMPWGPNQCDKIRDIEEAIPREIEANDIVFSVHIPLPSMEMSPWFQFMLFILQLDIAFKLNNQIRENAEVSMDVSLAYRDDMFAEWTEMAHERVPRKLKCTFTSPKTLEHEGRYYECDVLPFMEIGSVAHKYYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVWFAMKTFLTPSIFIIMVWYWRRITMMSRPPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQHERNHIAGYWKQVGPIAVGSFCLFIFDMCERGVQLTNPFYSIWTTDVGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKVRRLHYEGLIFRFKFLMLITLACAAMTVIFFIVSQVTEGHWKWGGVTVQVNSAFFTGIYGMWNLYVFALMFLYAPSHKNYGEDQSNGDLGVHSGEELQLTTTITHVDGPTEIYKLTRKEAQE", "length": 519, "header": "tr|A0AAA9SW08-1|A0ABI0NY61_BOVIN Computationally mapped isoform of Wnt ligand secretion mediator OS=Bos taurus OX=9913 GN=WLS PE=3 SV=1 CANONICAL=A0ABI0NY61-1" }, "locus": { "chromosome": "3", "start_pos": 77186493, "end_pos": 77092542, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098206.2", "url": "https://www.ensembl.org/id/ENSBTAT00000098206.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090665.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090665.1" } ] } }, { "isoform_ac": "A0ABI0NY61-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61/entry#A0ABI0NY61-1", "sequence": { "sequence": "MAGAIIENMSTKKLCIVGGILLVFQIIAFLVGGLIAPGPTTAVSYMSVKCVDVRKNHHKAKWLMPWGPNQCDKIRDIEEAIPREIEANDIVFSVHIPLPSMEMSPWFQFMLFILQLDIAFKLNNQIRENAEVSMDVSLAYRDDMFAEWTEMAHERVPRKLKCTFTSPKTLEHEGRYYECDVLPFMEIGSVAHKYYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVWFAMKTFLTPSIFIIMVWYWRRITMMSRPPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQHERNHIAGYWKQVGPIAVGSFCLFIFDMCERGVQLTNPFYSIWTTDVGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKVRRLHYEGLIFRFKFLMLITLACAAMTVIFFIVSQVTEGHWKWGGVTVQVNSAFFTGIYGMWNLYVFALMFLYAPSHKNYGEDQSNGDLGVHSGEELQLTTTITHVDGPTEIYKLTRKEAQE", "length": 541, "header": "tr|A0ABI0NY61-1|A0ABI0NY61_BOVIN Isoform 1 of Wnt ligand secretion mediator OS=Bos taurus OX=9913 GN=WLS PE=3 SV=1 CANONICAL=A0ABI0NY61-1" }, "locus": { "chromosome": "3", "start_pos": 77186493, "end_pos": 77071098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152112.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152112.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105129.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105129.1" } ] } }, { "isoform_ac": "E1BDN1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61/entry#E1BDN1-1", "sequence": { "sequence": "MAGAIIENMSTKKLCIVGGILLVFQIIAFLVGGLIAPGPTTAVSYMSVKCVDVRKNHHKAKWLMPWGPNQCDKIRDIEEAIPREIEANDIVFSVHIPLPSMEMSPWFQFMLFILQLDIAFKLNNQIRENAEVSMDVSLAYRDDMFAEWTEMAHERVPRKLKCTFTSPKTLEHEGRYYECDVLPFMEIGSVAHKYYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVWFAMKTFLTPSIFIIMVWYWRRITMMSRPPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQHERNHIAGYWKQVGPIAVGSFCLFIFDMCERGVQLTNPFYSIWTTDVGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKVRRLHYEISETKQEPQIHQQHIGEASQEDRGLIFRFKFLMLITLACAAMTVIFFIVSQVTEGHWKWGGVTVQVNSAFFTGIYGMWNLYVFALMFLYAPSHKNYGEDQSNGDLGVHSGEELQLTTTITHVDGPTEIYKLTRKEAQE", "length": 564, "header": "tr|E1BDN1-1|A0ABI0NY61_BOVIN Computationally mapped isoform of Wnt ligand secretion mediator OS=Bos taurus OX=9913 GN=WLS PE=3 SV=3 CANONICAL=A0ABI0NY61-1" }, "locus": { "chromosome": "3", "start_pos": 77186493, "end_pos": 77071098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017252.8", "url": "https://www.ensembl.org/id/ENSBTAT00000017252.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017252.6", "url": "https://www.ensembl.org/id/ENSBTAP00000017252.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 40, "start_aa": "Thr", "end_pos": 40, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr40", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:528123", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528123", "resource": "KEGG Pathway" }, { "id": "R-BTA-3238698", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3238698", "resource": "Reactome", "description": "WNT ligand biogenesis and trafficking" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NY61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NY61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NY61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NY61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NY61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NY61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" } ], "pmid": "" }, { "name": "organelle membrane", "id": "GO:0031090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031090", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NY61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NY61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NY61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NY61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" } ], "pmid": "" }, { "name": "positive regulation of Wnt protein secretion", "id": "GO:0061357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061357", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NY61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" } ], "pmid": "" }, { "name": "Wnt protein secretion", "id": "GO:0061355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061355", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NY61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "Wnt-protein binding", "id": "GO:0017147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017147", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NY61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NY61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" }, { "id": "PF21883", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21883" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Wntless GOLD", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 226, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NY61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY61" }, { "id": "PF06664", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06664" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Wntless-like transmembrane", "eco_id": "ECO_0000259", "start_pos": 227, "end_pos": 496, "start_aa": "Asn", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 40 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 406, "end_pos": 408 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NXL0-1", "uniprot_ac": "A0ABI0NXL0", "uniprot_id": "A0ABI0NXL0_BOVIN", "mass": { "chemical_mass": 93704.0, "monoisotopic_mass": 93704.0 }, "refseq": { "ac": "XP_010810796", "name": "transcription factor SOX-6 isoform X7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010810796" }, "gene_names": [ { "name": "SOX6", "type": "recommended", "evidence": [ { "id": "A0ABI0NXL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0" } ] }, { "name": "SOX6", "type": "synonym", "evidence": [ { "id": "XP_010810796", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010810796" } ] } ], "protein_names": [ { "name": "SRY-box transcription factor 6", "type": "synonym", "evidence": [ { "id": "A0ABI0NXL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0/entry#names_and_taxonomy" } ] }, { "name": "transcription factor SOX-6 isoform X7", "type": "synonym", "evidence": [ { "id": "XP_010810796", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010810796" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXL0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SOX6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0", "locus": { "chromosome": "15", "start_pos": 36542301, "end_pos": 36065303, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000044185", "url": "https://www.ensembl.org/id/ENSBTAG00000044185" } ] } } ], "crossref": [ { "id": "ENSBTAG00000044185", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000044185", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22042", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22042", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "534321", "url": "https://www.ncbi.nlm.nih.gov/gene/534321", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534321", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534321", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M0P9", "url": "https://www.orthodb.org/?gene=A0A3Q1M0P9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M911", "url": "https://www.orthodb.org/?gene=A0A3Q1M911", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BE01", "url": "https://www.orthodb.org/?gene=E1BE01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45789", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45789", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45789:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45789:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010810796", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010810796", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0P9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0P9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M911", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M911", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M911-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M911-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NE28", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NE28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NE28-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NE28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSQ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXL0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXL0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE01", "url": "https://www.uniprot.org/uniprotkb/E1BE01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BE01-1", "url": "https://www.uniprot.org/uniprotkb/E1BE01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSKQATSPFACTADGEEAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLVNTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHPQINPRLKGLSDRLGRSLDTFEHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNAAGAVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTVEPVKSPTSPTQSLFSASKTSPVNLPNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSTLNNMGLNNCRNEKERTRFENLGPQLTGKSSEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSSYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN", "length": 843, "header": "tr|A0ABI0NXL0-1|A0ABI0NXL0_BOVIN Isoform 1 of SRY-box transcription factor 6 OS=Bos taurus OX=9913 GN=SOX6 PE=4 SV=1 CANONICAL=A0ABI0NXL0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M0P9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0/entry#A0A3Q1M0P9-1", "sequence": { "sequence": "MGRMSSKQATSPFACTADGEEAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLVNTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNAAGAVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTVEPVKSPTSPTQSLFSASKTSPVNLPNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSTLNNMGLNNCRNEKERTRFENLGPQLTGKSSEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSSYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN", "length": 804, "header": "tr|A0A3Q1M0P9-1|A0ABI0NXL0_BOVIN Computationally mapped isoform of SRY-box transcription factor 6 OS=Bos taurus OX=9913 GN=SOX6 PE=4 SV=2 CANONICAL=A0ABI0NXL0-1" }, "locus": { "chromosome": "15", "start_pos": 36542019, "end_pos": 36065503, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079656.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079656.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063233.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063233.2" } ] } }, { "isoform_ac": "A0A3Q1M911-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0/entry#A0A3Q1M911-1", "sequence": { "sequence": "MSSKQATSPFACTADGEEAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLVNTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNAAGAVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTVEPVKSPTSPTQSLFSASKTSPVNLPNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSTLNNMGLNNCRNEKERTRFENLGPQLTGKSSEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSSYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN", "length": 802, "header": "tr|A0A3Q1M911-1|A0ABI0NXL0_BOVIN Computationally mapped isoform of SRY-box transcription factor 6 OS=Bos taurus OX=9913 GN=SOX6 PE=4 SV=2 CANONICAL=A0ABI0NXL0-1" }, "locus": { "chromosome": "15", "start_pos": 36542019, "end_pos": 36139262, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069703.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069703.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066611.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066611.2" } ] } }, { "isoform_ac": "A0A3Q1NE28-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0/entry#A0A3Q1NE28-1", "sequence": { "sequence": "MYSTDTRMSSKQATSPFACTADGEEAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLVNTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHPQINPRLKGLSDRLGRSLDTFEHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNAAGAVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTVEPVKSPTSPTQSLFSASKTSPVNLPNKSSIPSPIGGSLGRGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSTLNNMGLNNCRNEKERTRFENLGPQLTGKSSEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSSYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN", "length": 835, "header": "tr|A0A3Q1NE28-1|A0ABI0NXL0_BOVIN Computationally mapped isoform of SRY-box transcription factor 6 OS=Bos taurus OX=9913 GN=SOX6 PE=4 SV=1 CANONICAL=A0ABI0NXL0-1" }, "locus": { "chromosome": "15", "start_pos": 36542019, "end_pos": 36070585, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066730.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066730.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069818.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069818.2" } ] } }, { "isoform_ac": "A0ABI0NSQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0/entry#A0ABI0NSQ9-1", "sequence": { "sequence": "MSSKQATSPFACTADGEEAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLVNTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQLYAAQLASMQVSPGAKMPSTPQPPNAAGAVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTVEPVKSPTSPTQSLFSASKTSPVNLPNKSSIPSPIGGSLGRGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSTLNNMGLNNCRNEKERTRFENLGPQLTGKSSEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSSYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN", "length": 786, "header": "tr|A0ABI0NSQ9-1|A0ABI0NXL0_BOVIN Computationally mapped isoform of SRY-box transcription factor 6 OS=Bos taurus OX=9913 GN=SOX6 PE=4 SV=1 CANONICAL=A0ABI0NXL0-1" }, "locus": { "chromosome": "15", "start_pos": 36542019, "end_pos": 36139262, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143657.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143657.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107203.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107203.1" } ] } }, { "isoform_ac": "A0ABI0NXL0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0/entry#A0ABI0NXL0-1", "sequence": { "sequence": "MSSKQATSPFACTADGEEAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLVNTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHPQINPRLKGLSDRLGRSLDTFEHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNAAGAVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTVEPVKSPTSPTQSLFSASKTSPVNLPNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSTLNNMGLNNCRNEKERTRFENLGPQLTGKSSEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSSYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN", "length": 843, "header": "tr|A0ABI0NXL0-1|A0ABI0NXL0_BOVIN Isoform 1 of SRY-box transcription factor 6 OS=Bos taurus OX=9913 GN=SOX6 PE=4 SV=1 CANONICAL=A0ABI0NXL0-1" }, "locus": { "chromosome": "15", "start_pos": 36542019, "end_pos": 36139262, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143693.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143693.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104811.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104811.1" } ] } }, { "isoform_ac": "E1BE01-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0/entry#E1BE01-1", "sequence": { "sequence": "MKGHGELQGHERRMSSKQATSPFACTADGEEAMTQDLTSREKEEGSDQHVASHLPLHPIMHNKPHSEELPTLVNTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDREIMTSVTFGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHPQINPRLKGLSDRLGRSLDTFEHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNAAGAVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTVEPVKSPTSPTQSLFSASKTSPVNLPNKSSIPSPIGGSLGRGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSTLNNMGLNNCRNEKERTRFENLGPQLTGKSSEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSSYGMKTDGGSLAGNEMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN", "length": 841, "header": "tr|E1BE01-1|A0ABI0NXL0_BOVIN Computationally mapped isoform of SRY-box transcription factor 6 OS=Bos taurus OX=9913 GN=SOX6 PE=4 SV=4 CANONICAL=A0ABI0NXL0-1" }, "locus": { "chromosome": "15", "start_pos": 36542019, "end_pos": 36065326, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061473.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061473.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053691.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053691.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:534321", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534321", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXL0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXL0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXL0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXL0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NXL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXL0" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 636, "end_pos": 704, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 169, "end_pos": 171 }, { "start_pos": 427, "end_pos": 429 }, { "start_pos": 461, "end_pos": 463 }, { "start_pos": 598, "end_pos": 600 }, { "start_pos": 665, "end_pos": 667 }, { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P089-1", "uniprot_ac": "A0ABI0P089", "uniprot_id": "A0ABI0P089_BOVIN", "mass": { "chemical_mass": 58326.0, "monoisotopic_mass": 58326.0 }, "refseq": { "ac": "XP_002691016", "name": "signal peptide peptidase-like 2A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691016" }, "gene_names": [ { "name": "SPPL2A", "type": "recommended", "evidence": [ { "id": "A0ABI0P089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089" } ] }, { "name": "SPPL2A", "type": "synonym", "evidence": [ { "id": "XP_002691016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691016" } ] } ], "protein_names": [ { "name": "Signal peptide peptidase-like 2A", "type": "recommended", "evidence": [ { "id": "A0ABI0P089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089/entry#names_and_taxonomy" } ] }, { "name": "Intramembrane protease 3", "type": "synonym", "evidence": [ { "id": "A0ABI0P089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089/entry#names_and_taxonomy" } ] }, { "name": "Presenilin-like protein 2", "type": "synonym", "evidence": [ { "id": "A0ABI0P089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089/entry#names_and_taxonomy" } ] }, { "name": "signal peptide peptidase-like 2A", "type": "synonym", "evidence": [ { "id": "XP_002691016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691016" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P089", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SPPL2A", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089", "locus": { "chromosome": "10", "start_pos": 59629196, "end_pos": 59575808, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011831", "url": "https://www.ensembl.org/id/ENSBTAG00000011831" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011831", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011831", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02129", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02129", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "530325", "url": "https://www.ncbi.nlm.nih.gov/gene/530325", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007369", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007369", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:530325", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:530325", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M238", "url": "https://www.orthodb.org/?gene=A0A3Q1M238", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MBP7", "url": "https://www.orthodb.org/?gene=A0A3Q1MBP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MW85", "url": "https://www.orthodb.org/?gene=A0A3Q1MW85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MG08", "url": "https://www.orthodb.org/?gene=F1MG08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12174", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12174", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12174:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12174:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5357905", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357905", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002691016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691016", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M238", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M238", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M238-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M238-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MBP7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MBP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MW85", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MW85-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKP3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKP3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P089", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P089-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MG08", "url": "https://www.uniprot.org/uniprotkb/F1MG08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MG08-1", "url": "https://www.uniprot.org/uniprotkb/F1MG08-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRQSPLPPAAAALLLCFLLPLTAAHEAILHASGNGRPSPSKDYCMLYNPHWTSLPSTLENATSMSLMNLTTTPLCNVSDIPPDGIKNKAVVVQWGTCHFLEKAKIAQTGGAEALLVANNSVLFPPSGNKSEFLDVKILIAFINHKDFKDMKQTLGDNIMVKMYSPSWPNFDYTMVVIFVIAVFTVALGGYWSGLIELENMKAMTNTEDREMRKKKEEYFTFSPLTVIIFVVICCIMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALVRKIPCGQCTITCRGKSIEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKLPVVIRVPKLAYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVEIGSSVYYVSSTIAYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASLVAWRRKEMKKFWKGSSYQMMDHLDYATNEENPGTAGEQIVQQ", "length": 523, "header": "tr|A0ABI0P089-1|A0ABI0P089_BOVIN Isoform 1 of Signal peptide peptidase-like 2A OS=Bos taurus OX=9913 GN=SPPL2A PE=3 SV=1 CANONICAL=A0ABI0P089-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M238-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089/entry#A0A3Q1M238-1", "sequence": { "sequence": "MGRQSPLPPAAAALLLCFLLPLTAAHEAILHASGNGRPSPSKDYCMLYNPHWTSLPSTLENATSMSLMNLTTTPLCNVSDIPPDGIKNKAVVVQWGTCHFLEKAKIAQTGGAEALLVANNSVLFPPSGNKSEFLDVKILIAFINHKDFKDMKQTLGDNIMVKMYSPSWPNFDYTMVVIFVIAVFTVALGGYWSGLIELENMKAMTNTEDREMRKKKEEYFTFSPLTVIIFVVICCIMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALVRKIPCGQCTITCRGKSIEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKNDGNLVEATAQPSAPHEKLPVVIRVPKLAYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVEIGSSVYYVSSTIAYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASLVAWRRKEMKKFWKGSSYQYSFKGAVVYYKHLSSFLFLCCFLRRKEMLDDGPSGLCNK", "length": 556, "header": "tr|A0A3Q1M238-1|A0ABI0P089_BOVIN Computationally mapped isoform of Signal peptide peptidase-like 2A OS=Bos taurus OX=9913 GN=SPPL2A PE=3 SV=3 CANONICAL=A0ABI0P089-1" }, "locus": { "chromosome": "10", "start_pos": 59628149, "end_pos": 59576026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076826.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076826.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063826.3", "url": "https://www.ensembl.org/id/ENSBTAP00000063826.3" } ] } }, { "isoform_ac": "A0A3Q1MBP7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089/entry#A0A3Q1MBP7-1", "sequence": { "sequence": "MGRQSPLPPAAAALLLCFLLPLTAAHEAILHASGNGRPSPSKDYCMLYNPHWTSLPSTLENATSMSLMNLTTTPLCNVSDIPPDGIKNKAVVVQWGTCHFLEKAKIAQTGGAEALLVANNSVLFPPSGNKSEFLDVKILIAFINHKDFKDMKQTLGDNIMVKMYSPSWPNFDYTMVVIFVIAVFTVALGGYWSGLIELENMKAMTNTEDREMRKKKEEYFTFSPLTVIIFVVICCIMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALVRKIPCGQCTITCRGKSIEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKLPVVIRVPKLAYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVEIGSSVYYVSSTIAYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASLVAWRRKEMKKFWKGSSYQMMDHLDYATNEENPGTAGEQIVQQ", "length": 504, "header": "tr|A0A3Q1MBP7-1|A0ABI0P089_BOVIN Computationally mapped isoform of Signal peptide peptidase-like 2A OS=Bos taurus OX=9913 GN=SPPL2A PE=3 SV=2 CANONICAL=A0ABI0P089-1" }, "locus": { "chromosome": "10", "start_pos": 59628192, "end_pos": 59576026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077127.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077127.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071502.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071502.2" } ] } }, { "isoform_ac": "A0A3Q1MW85-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089/entry#A0A3Q1MW85-1", "sequence": { "sequence": "MGRQSPLPPAAAALLLCFLLPLTAAHEAILHASGNGRPSPSKDYCMLYNPHWTSLPSTLENATSMSLMNLTTTPLCNVSDIPPDGIKNKAVVVQWGTCHFLEKAKIAQTGGAEALLVANNSVLFPPSGNKSEFLDVKILIAFINHKDFKDMKQTLGDNIMVKMYSPSWPNFDYTMVVIFVIAVFTVALGGYWSGLIELENMKAMTNTEDREMRKKKEEYFTFSPLTVIIFVVICCIMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALVRKIPCGQCTITCRGKSIEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKNGESIMVELAAGPFGNNEKLPVVIRVPKLAYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVEIGSSVYYVSSTIAYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASLVAWRRKEMKKFWKGSSYQMMDHLDYATNEENPGTAGEQIVQQ", "length": 498, "header": "tr|A0A3Q1MW85-1|A0ABI0P089_BOVIN Computationally mapped isoform of Signal peptide peptidase-like 2A OS=Bos taurus OX=9913 GN=SPPL2A PE=3 SV=2 CANONICAL=A0ABI0P089-1" }, "locus": { "chromosome": "10", "start_pos": 59628192, "end_pos": 59576026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070521.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070521.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059602.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059602.2" } ] } }, { "isoform_ac": "A0ABI0NKP3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089/entry#A0ABI0NKP3-1", "sequence": { "sequence": "MGRQSPLPPAAAALLLCFLLPLTAAHEAILHASGNGRPSPSKDYCMLYNPHWTSLPSTLENATSMSLMNLTTTPLCNVSDIPPDGIKNKAVVVQWGTCHFLEKAKIAQTGGAEALLVANNSVLFPPSGNKSEFLDVKILIAFINHKDFKDMKQTLGDNIMVKMYSPSWPNFDYTMVVIFVIAVFTVALGGYWSGLIELENMKAMTNTEDREMRKKKEEYFTFSPLTVIIFVVICCIMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALVRKIPCGQCTITCRGKSIEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKNDGNLVEATAQPSAPHEKLPVVIRVPKLAYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVEIGSSVYYVSSTIAYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASLVAWRRKEMKKFWKGSSYQMMDHLDYATNEENPGTAGEQIVQQ", "length": 541, "header": "tr|A0ABI0NKP3-1|A0ABI0P089_BOVIN Computationally mapped isoform of Signal peptide peptidase-like 2A OS=Bos taurus OX=9913 GN=SPPL2A PE=3 SV=1 CANONICAL=A0ABI0P089-1" }, "locus": { "chromosome": "10", "start_pos": 59628192, "end_pos": 59576026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140131.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140131.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105368.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105368.1" } ] } }, { "isoform_ac": "A0ABI0P089-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089/entry#A0ABI0P089-1", "sequence": { "sequence": "MGRQSPLPPAAAALLLCFLLPLTAAHEAILHASGNGRPSPSKDYCMLYNPHWTSLPSTLENATSMSLMNLTTTPLCNVSDIPPDGIKNKAVVVQWGTCHFLEKAKIAQTGGAEALLVANNSVLFPPSGNKSEFLDVKILIAFINHKDFKDMKQTLGDNIMVKMYSPSWPNFDYTMVVIFVIAVFTVALGGYWSGLIELENMKAMTNTEDREMRKKKEEYFTFSPLTVIIFVVICCIMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALVRKIPCGQCTITCRGKSIEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKLPVVIRVPKLAYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVEIGSSVYYVSSTIAYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASLVAWRRKEMKKFWKGSSYQMMDHLDYATNEENPGTAGEQIVQQ", "length": 523, "header": "tr|A0ABI0P089-1|A0ABI0P089_BOVIN Isoform 1 of Signal peptide peptidase-like 2A OS=Bos taurus OX=9913 GN=SPPL2A PE=3 SV=1 CANONICAL=A0ABI0P089-1" }, "locus": { "chromosome": "10", "start_pos": 59628192, "end_pos": 59576026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141779.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141779.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106300.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106300.1" } ] } }, { "isoform_ac": "F1MG08-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089/entry#F1MG08-1", "sequence": { "sequence": "MGRQSPLPPAAAALLLCFLLPLTAAHEAILHASGNGRPSPSKDYCMLYNPHWTSLPSTLENATSMSLMNLTTTPLCNVSDIPPDGIKNKAVVVQWGTCHFLEKAKIAQTGGAEALLVANNSVLFPPSGNKSEFLDVKILIAFINHKDFKDMKQTLGDNIMVKMYSPSWPNFDYTMVVIFVIAVFTVALGGYWSGLIELENMKAMTNTEDREMRKKKEEYFTFSPLTVIIFVVICCIMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALVRKIPCGQCTITCRGKSIEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKLPVVIRVPKLAYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVEIGSSVYYVSSTIDDGPSGLCNK", "length": 455, "header": "tr|F1MG08-1|A0ABI0P089_BOVIN Computationally mapped isoform of Signal peptide peptidase-like 2A OS=Bos taurus OX=9913 GN=SPPL2A PE=3 SV=3 CANONICAL=A0ABI0P089-1" }, "locus": { "chromosome": "10", "start_pos": 59628149, "end_pos": 59576026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015701.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015701.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015701.6", "url": "https://www.ensembl.org/id/ENSBTAP00000015701.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:530325", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:530325", "resource": "KEGG Pathway" }, { "id": "R-BTA-5357905", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5357905", "resource": "Reactome", "description": "Regulation of TNFR1 signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasmic side of endoplasmic reticulum membrane", "id": "GO:0098554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098554", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P089", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P089", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P089", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089" } ], "pmid": "" }, { "name": "Golgi-associated vesicle membrane", "id": "GO:0030660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030660", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P089", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089" } ], "pmid": "" }, { "name": "lumenal side of endoplasmic reticulum membrane", "id": "GO:0098553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098553", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P089", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P089", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "membrane protein ectodomain proteolysis", "id": "GO:0006509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006509", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P089", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089" } ], "pmid": "" }, { "name": "regulation of immune response", "id": "GO:0050776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050776", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P089", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089" } ], "pmid": "" }, { "name": "membrane protein intracellular domain proteolysis", "id": "GO:0031293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031293", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P089", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089" } ], "pmid": "" }, { "name": "membrane protein proteolysis", "id": "GO:0033619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033619", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P089", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P089", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089" } ], "pmid": "" }, { "name": "aspartic endopeptidase activity, intramembrane cleaving", "id": "GO:0042500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042500", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P089", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P089" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P094-1", "uniprot_ac": "A0ABI0P094", "uniprot_id": "A0ABI0P094_BOVIN", "mass": { "chemical_mass": 35721.0, "monoisotopic_mass": 35721.0 }, "refseq": {}, "gene_names": [ { "name": "HMOX2", "type": "recommended", "evidence": [ { "id": "A0ABI0P094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094" } ] } ], "protein_names": [ { "name": "Heme oxygenase 1", "type": "recommended", "evidence": [ { "id": "A0ABI0P094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094/entry#names_and_taxonomy" } ] }, { "name": "1.14.14.18", "type": "synonym", "evidence": [ { "id": "A0ABI0P094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. Affords protection against programmed cell death and this cytoprotective effect relies on its ability to catabolize free heme and prevent it from sensitizing cells to undergo apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NPI3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPI3#function" }, { "database": "UniProtKB", "id": "ARBA00059879", "url": "https://www.uniprot.org/uniprotkb/ARBA00059879#function" }, { "database": "UniProtKB", "id": "A0ABI0P094", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094#function" }, { "database": "UniProtKB", "id": "G3N371", "url": "https://www.uniprot.org/uniprotkb/G3N371#function" }, { "database": "UniProtKB", "id": "F1MTY9", "url": "https://www.uniprot.org/uniprotkb/F1MTY9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P094", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HMOX2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094", "locus": { "chromosome": "25", "start_pos": 3654155, "end_pos": 3626012, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018937", "url": "https://www.ensembl.org/id/ENSBTAG00000018937" } ] } } ], "crossref": [ { "id": "ENSBTAG00000018937", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018937", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19165", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19165", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "510243", "url": "https://www.ncbi.nlm.nih.gov/gene/510243", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:510243", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510243", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NRAFEYN", "url": "https://omabrowser.org/oma/group/NRAFEYN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MTY9", "url": "https://www.orthodb.org/?gene=F1MTY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N371", "url": "https://www.orthodb.org/?gene=G3N371", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10720", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10720", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10720:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10720:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01126", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01126", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-189483", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-189483", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-917937", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-917937", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9707564", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9707564", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NPI3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPI3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P094", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P094-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MTY9", "url": "https://www.uniprot.org/uniprotkb/F1MTY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MTY9-1", "url": "https://www.uniprot.org/uniprotkb/F1MTY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N371", "url": "https://www.uniprot.org/uniprotkb/G3N371", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N371-1", "url": "https://www.uniprot.org/uniprotkb/G3N371-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAELETSEGLDEPEKKISGVPEKENHTRMADLSELLKEGTKESHDRAENTQFVKDFLKGNIRKELFKLATTALYFTYSALEEEIDRNKDHPAFAPLYFPTELHRKKALIRDMEYLYGEHWEEQAQCSEATRKYVERIHEVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNLETKEKIVEEANKAFEFNMQVFNELDQAGSLLAKETLEDGLPVHDGKGDLRKCPYYAAQLDKGALEGSSCPFGAALAVLRRPGLQFLLAASVALAAGLLAWYSM", "length": 316, "header": "tr|A0ABI0P094-1|A0ABI0P094_BOVIN Isoform 1 of Heme oxygenase 1 OS=Bos taurus OX=9913 GN=HMOX2 PE=3 SV=1 CANONICAL=A0ABI0P094-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NPI3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094/entry#A0ABI0NPI3-1", "sequence": { "sequence": "MSAELETSEGLDEPEKKISGVPEKENHTRMADLSELLKEGTKESHDRAENTQFVKDFLKGNIRKELFKLATTALYFTYSALEEEIDRNKDHPAFAPLYFPTELHRKKALIRDMEYLYGEHWEEQAQCSEATRKYVERIHEVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNLETKEKIVEEANKAFEFNMQVFNELDQAGSLLAKETLEDGLPAHDGLPAHGRLPTQDGLPVHDGKGDLRKCPYYAAQLDKGALEGSSCPFGAALAVLRRPGLQFLLAASVALAAGLLAWYSM", "length": 334, "header": "tr|A0ABI0NPI3-1|A0ABI0P094_BOVIN Computationally mapped isoform of Heme oxygenase 1 OS=Bos taurus OX=9913 GN=HMOX2 PE=3 SV=1 CANONICAL=A0ABI0P094-1" }, "locus": { "chromosome": "25", "start_pos": 3653531, "end_pos": 3650264, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139103.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139103.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104974.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104974.1" } ] } }, { "isoform_ac": "A0ABI0P094-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094/entry#A0ABI0P094-1", "sequence": { "sequence": "MSAELETSEGLDEPEKKISGVPEKENHTRMADLSELLKEGTKESHDRAENTQFVKDFLKGNIRKELFKLATTALYFTYSALEEEIDRNKDHPAFAPLYFPTELHRKKALIRDMEYLYGEHWEEQAQCSEATRKYVERIHEVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNLETKEKIVEEANKAFEFNMQVFNELDQAGSLLAKETLEDGLPVHDGKGDLRKCPYYAAQLDKGALEGSSCPFGAALAVLRRPGLQFLLAASVALAAGLLAWYSM", "length": 316, "header": "tr|A0ABI0P094-1|A0ABI0P094_BOVIN Isoform 1 of Heme oxygenase 1 OS=Bos taurus OX=9913 GN=HMOX2 PE=3 SV=1 CANONICAL=A0ABI0P094-1" }, "locus": { "chromosome": "25", "start_pos": 3653531, "end_pos": 3650264, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148518.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148518.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107130.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107130.1" } ] } }, { "isoform_ac": "F1MTY9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094/entry#F1MTY9-1", "sequence": { "sequence": "MLVVTAAPSKNETRGVRAAAMSAELETSEGLDEPEKKISGVPEKENHTRMADLSELLKEGTKESHDRAENTQFVKDFLKGNIRKELFKLATTALYFTYSALEEEIDRNKDHPAFAPLYFPTELHRKKALIRDMEYLYGEHWEEQAQCSEATRKYVERIHEVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNLETKEKIVEEANKAFEFNMQVFNELDQAGSLLAKETLEDGLPAHDGLPAHGRLPTQDGLPVHDGKGDLRKCPYYAAQLDKGALEGSSCPFGAALAVLRRPGLQFLLAASVALAAGLLAWYSM", "length": 354, "header": "tr|F1MTY9-1|A0ABI0P094_BOVIN Computationally mapped isoform of Heme oxygenase 1 OS=Bos taurus OX=9913 GN=HMOX2 PE=3 SV=3 CANONICAL=A0ABI0P094-1" }, "locus": { "chromosome": "25", "start_pos": 3653531, "end_pos": 3614421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047056.5", "url": "https://www.ensembl.org/id/ENSBTAT00000047056.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044292.4", "url": "https://www.ensembl.org/id/ENSBTAP00000044292.4" } ] } }, { "isoform_ac": "G3N371-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094/entry#G3N371-1", "sequence": { "sequence": "MSAELETSEGLDEPEKKISGVPEKENHTRMADLSELLKEGTKESHDRAENTQFVKDFLKGNIRKELFKLATTALYFTYSALEEEIDRNKDHPAFAPLYFPTELHRKKALIRDMEYLYGEHWEEQAQCSEATRKYVERIHEVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGPPCLHPRPNCHLR", "length": 194, "header": "tr|G3N371-1|A0ABI0P094_BOVIN Computationally mapped isoform of Heme oxygenase 1 OS=Bos taurus OX=9913 GN=HMOX2 PE=3 SV=2 CANONICAL=A0ABI0P094-1" }, "locus": { "chromosome": "25", "start_pos": 3653615, "end_pos": 3650264, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063149.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063149.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056345.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056345.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:510243", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510243", "resource": "KEGG Pathway" }, { "id": "R-BTA-189483", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-189483", "resource": "Reactome", "description": "Heme degradation" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-BTA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-BTA-917937", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-917937", "resource": "Reactome", "description": "Iron uptake and transport" }, { "id": "R-BTA-9707564", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9707564", "resource": "Reactome", "description": "Cytoprotection by HMOX1" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VSV5-1", "protein_name": "Heme oxygenase 1", "gene_name": "HMOX2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVELETSEGVDEPEEKSSGAPEKENHTRMADLSELLKEGTKEAHDRAESTQFVKDFLKGNIRKELFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPTELHRKEALVKDMEYFYGGDWEEQAQCSEATRKYVERIHYVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQFYRARMNALDLNLETKEKIVEEANKAFEYNMQVFNELDQAGSLLAKETLADGLPVHDGKGDVRKCPYYSGEQDKGALEGSSCPFQTALAVLSKPSLQFLLAASVALAASLLAWYYM", "length": 316 }, "evidence": [ { "id": "A0ABI0P094", "url": "https://omabrowser.org/oma/group/A0ABI0P094/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YXK7-1", "protein_name": "Heme oxygenase", "gene_name": "HMOX2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSVMESSEGGDEGESLRYEELEDDSVSPTDLSELLKEGTKESHDRAENTQFVKDFLKGQIKKELFKLATTALYFTYTALEEEMDRNKDNPVFAPLYFPLELHRKEALIKDMKYFYGEDWKEKIQCSDATQQYVDRIHHVGQHEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTEEGIQFYTFENISNAQKFKQLYRARLNALDLDKNCKERIVEEANRAFRFNMEVFDELDKIGRSLAEEAQDGGVPVHDGKGDVRKCPYYADKLAGNAAAGCPYHTAVALAKQPIVQLILAACVAVAAGAAAWYVM", "length": 313 }, "evidence": [ { "id": "A0ABI0P094", "url": "https://omabrowser.org/oma/group/A0ABI0P094/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7F079-1", "protein_name": "heme oxygenase (biliverdin-producing)", "gene_name": "hmox2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSAVRTEDAANGTSTANGGGGVKCEEGGVTVLRPTDLSEMLAAGTKEVHQKAENTEFVKDFLRGRIRKELFKLGHVALYFTYSALEEEIERNKDHPQFAPLYFPHELHRRDALAQDLQFFYGSDWQTQISISPATQRYVQRIHQIGKDEPALLVAHAYTRYMGDLSGGQVLRKVAQRALKLPASGDGLNFYMFDNVSNAKAFKQLYRSRMNELELQQDTKLKIVEEAVLAFQFNIEIFEEIGEVGQTLEDDVFDAAPVHGEMQGDISQCPYHAAKMAASGGSSYVCQIAKTVLKNPSGQVLLAAWIAALAGLAAWYLM", "length": 318 }, "evidence": [ { "id": "A0ABI0P094", "url": "https://omabrowser.org/oma/group/A0ABI0P094/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HS67-1", "protein_name": "Heme oxygenase", "gene_name": "Hmox2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSEVETSEGVDESEKKNSVAPEKENHTKMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPMELHRKEALIKDMEYFFGEDWEEQVKCSEAAQKYVDRIHYVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFEHVDNAQQFKQFYRARMNALDMNLKTKERIVEEANKAFEYNMQIFSELDQAGSMLARENQEDGFPMHDGKGDVRKCPFYAAQPDKGTLEGSNCPFRTAMAMLRKPSLQLVLAVSVALAAGLLAWYYM", "length": 316 }, "evidence": [ { "id": "A0ABI0P094", "url": "https://omabrowser.org/oma/group/A0ABI0P094/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O70252-1", "protein_name": "Heme oxygenase 2", "gene_name": "Hmox2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSEVETSEGVDESEKNSMAPEKENHTKMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPTELHRKAALIKDMKYFFGENWEEQVKCSEAAQKYVDRIHYVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFEHVDNAQQFKQFYRARMNALDLNLKTKERIVEEANKAFEYNMQIFSELDQAGSMLARETLEDGLPVHDGKGDIRKCPFYAAQPDKGTLGGSNCPFQTTVAVLRKPSLQLILAASVALVAGLLAWYYM", "length": 315 }, "evidence": [ { "id": "A0ABI0P094", "url": "https://omabrowser.org/oma/group/A0ABI0P094/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P23711-1", "protein_name": "Heme oxygenase 2", "gene_name": "Hmox2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSEVETSEGVDESENNSTAPEKENHTKMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPTELHRKEALIKDMEYFFGENWEEQVKCSEAAQKYVDRIHYVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFEHVDNAQQFKQFYRARMNALDLSMKTKERIVEEANKAFEYNMQIFSELDQAGSMLTKETLEDGLPVHDGKGDVRKCPFYAAQPDKGTLGGSNCPFRTAMAVLRKPSLQLILAASVALVAGLLAWYYM", "length": 315 }, "evidence": [ { "id": "A0ABI0P094", "url": "https://omabrowser.org/oma/group/A0ABI0P094/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P30519-1", "protein_name": "Heme oxygenase 2", "gene_name": "HMOX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAEVETSEGVDESEKKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQAGSTLARETLEDGFPVHDGKGDMRKCPFYAAEQDKGALEGSSCPFRTAMAVLRKPSLQFILAAGVALAAGLLAWYYM", "length": 316 }, "evidence": [ { "id": "A0ABI0P094", "url": "https://omabrowser.org/oma/group/A0ABI0P094/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P094", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P094", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094" } ], "pmid": "" }, { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P094", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094" } ], "pmid": "" }, { "name": "heme catabolic process", "id": "GO:0042167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042167", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P094", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094" } ], "pmid": "" }, { "name": "heme oxidation", "id": "GO:0006788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006788", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P094", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P094", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P094", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094" } ], "pmid": "" }, { "name": "heme oxygenase (decyclizing) activity", "id": "GO:0004392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004392", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P094", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-189398", "name": "HMOX1 dimer, HMOX2 cleave heme", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-29364", "R-ALL-29368", "R-ALL-71185" ], "output_participant_list": [ "R-ALL-71067", "R-ALL-189385", "R-ALL-189396" ], "enzyme_list": [ "Q5E9F2-1", "A0ABI0P094-1" ], "evidence": [ { "id": "R-BTA-189398", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-189398" } ] }, { "id": "R-BTA-6799350", "name": "Exocytosis of specific granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, specific granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q10741-1", "Q3ZBY7-1", "A0A3Q1MGR4-1", "Q05589-1", "F1MLP3-1", "F1MMX5-1", "F1MQP2-1", "P62833-1", "Q1JPA0-1", "Q27955-1", "A0A3Q1M9T8-1", "A0A3Q1LL74-1", "A0ABI0P094-1", "A0AAA9SAV7-1", "A0A3Q1M6K1-1", "O46522-1", "E1BFE2-1" ], "evidence": [ { "id": "R-BTA-6799350", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6799350" } ] }, { "id": "R-BTA-9013009", "name": "RHOA binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61585-1", "Q3ZC07-1", "F1MFK1-1", "A0AAA9TNL3-1", "A0A3Q1LL74-1", "A0ABI0P094-1", "A0A3Q1MW77-1", "A1A4I4-1", "A0A3Q1LM61-1" ], "evidence": [ { "id": "R-BTA-9013009", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013009" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-189385", "participant_name": "CO [cytosol]", "crossref": [ { "id": "9531", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "17245", "database": "ChEBI", "url": "" }, { "id": "HMDB0001361", "database": "HMDB Metabolite", "url": "" }, { "id": "C00237", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-189396", "participant_name": "BV [cytosol]", "crossref": [ { "id": "ZINC000053276076", "database": "ZINC", "url": "" }, { "id": "57991", "database": "ChEBI", "url": "" }, { "id": "C00500", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-29364", "participant_name": "NADPH [cytosol]", "crossref": [ { "id": "57783", "database": "ChEBI", "url": "" }, { "id": "ZINC000008215411", "database": "ZINC", "url": "" }, { "id": "C00005", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-29368", "participant_name": "O2 [cytosol]", "crossref": [ { "id": "15379", "database": "ChEBI", "url": "" }, { "id": "8145133", "database": "PubChem Substance", "url": "" }, { "id": "C00007", "database": "COMPOUND", "url": "" }, { "id": "HMDB0001377", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-71067", "participant_name": "Fe2+ [cytosol]", "crossref": [ { "id": "C14818", "database": "KEGG Gene", "url": "" }, { "id": "27284", "database": "PubChem Compound", "url": "" }, { "id": "29033", "database": "ChEBI", "url": "" }, { "id": "FE+2", "database": "AraCyc", "url": "" }, { "id": "C14818", "database": "COMPOUND", "url": "" }, { "id": "HMDB0000692", "database": "HMDB Metabolite", "url": "" }, { "id": "C00023", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-71185", "participant_name": "ferroheme [cytosol]", "crossref": [ { "id": "60344", "database": "ChEBI", "url": "" }, { "id": "C00032", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LL74", "gene_name": "PLD1", "activity": [ { "ec_number": "3.1.4.4", "activity": "a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + ethanolamine + H(+).", "evidence": [ { "id": "A0A3Q1LL74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL74" } ] }, { "ec_number": "3.1.4.4", "activity": "", "evidence": [ { "id": "A0A3Q1LL74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL74" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1M6K1", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] } ] }, { "uniprot_ac": "A0A3Q1M9T8", "gene_name": "ATP11A", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A3Q1M9T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9T8" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A3Q1M9T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9T8" } ] } ] }, { "uniprot_ac": "A0A3Q1MGR4", "gene_name": "RAB37", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0AAA9SAV7", "gene_name": "AGPAT2", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0AAA9SAV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAV7" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "A0AAA9SAV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0ABI0P094", "gene_name": "HMOX2", "activity": [ { "ec_number": "1.14.14.18", "activity": "heme b + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = biliverdin IXalpha + CO + Fe(2+) + 3 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+).", "evidence": [ { "id": "A0ABI0P094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094" } ] }, { "ec_number": "1.14.14.18", "activity": "", "evidence": [ { "id": "A0ABI0P094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P094" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "E1BFE2", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MLP3", "gene_name": "BST1", "activity": [ { "ec_number": "3.2.2.6", "activity": "NAD(+) + H2O = ADP-D-ribose + nicotinamide + H(+).", "evidence": [ { "id": "F1MLP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLP3" } ] }, { "ec_number": "3.2.2.6", "activity": "", "evidence": [ { "id": "F1MLP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLP3" } ] } ] }, { "uniprot_ac": "F1MMX5", "gene_name": "ATP8B4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MMX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMX5" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MMX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMX5" } ] } ] }, { "uniprot_ac": "F1MQP2", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "F1MQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQP2" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "F1MQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQP2" } ] } ] }, { "uniprot_ac": "O46522", "gene_name": "CYBB", "activity": [ { "ec_number": "1.6.3.-", "activity": "", "evidence": [ { "id": "O46522", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46522" } ] } ] }, { "uniprot_ac": "P61585", "gene_name": "RHOA", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P61585", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61585" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P61585", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61585" } ] } ] }, { "uniprot_ac": "P62833", "gene_name": "RAP1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P62833", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62833" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P62833", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62833" } ] } ] }, { "uniprot_ac": "Q05589", "gene_name": "PLAU", "activity": [ { "ec_number": "3.4.21.73", "activity": "Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin.", "evidence": [ { "id": "Q05589", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05589" } ] }, { "ec_number": "3.4.21.73", "activity": "", "evidence": [ { "id": "Q05589", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05589" } ] } ] }, { "uniprot_ac": "Q10741", "gene_name": "ADAM10", "activity": [ { "ec_number": "3.4.24.81", "activity": "Endopeptidase of broad specificity.", "evidence": [ { "id": "Q10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q10741" } ] }, { "ec_number": "3.4.24.81", "activity": "", "evidence": [ { "id": "Q10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q10741" } ] } ] }, { "uniprot_ac": "Q1JPA0", "gene_name": "ALDH3B1", "activity": [ { "ec_number": "1.2.1.5", "activity": "an aldehyde + NADP(+) + H2O = a carboxylate + NADPH + 2 H(+).", "evidence": [ { "id": "Q1JPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPA0" } ] }, { "ec_number": "1.2.1.28", "activity": "benzaldehyde + NAD(+) + H2O = benzoate + NADH + 2 H(+).", "evidence": [ { "id": "Q1JPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPA0" } ] }, { "ec_number": "1.2.1.7", "activity": "benzaldehyde + NADP(+) + H2O = benzoate + NADPH + 2 H(+).", "evidence": [ { "id": "Q1JPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPA0" } ] }, { "ec_number": "1.2.1.48", "activity": "a long-chain fatty aldehyde + NAD(+) + H2O = a long-chain fatty acid + NADH + 2 H(+).", "evidence": [ { "id": "Q1JPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPA0" } ] }, { "ec_number": "1.2.1.5", "activity": "", "evidence": [ { "id": "Q1JPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPA0" } ] }, { "ec_number": "1.2.1.7", "activity": "", "evidence": [ { "id": "Q1JPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPA0" } ] }, { "ec_number": "1.2.1.28", "activity": "", "evidence": [ { "id": "Q1JPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPA0" } ] } ] }, { "uniprot_ac": "Q27955", "gene_name": "KCNAB2", "activity": [ { "ec_number": "1.1.1.-", "activity": "", "evidence": [ { "id": "Q27955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27955" } ] } ] }, { "uniprot_ac": "Q3ZBY7", "gene_name": "DEGS1", "activity": [ { "ec_number": "1.14.19.17", "activity": "an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O.", "evidence": [ { "id": "Q3ZBY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBY7" } ] }, { "ec_number": "5.2.1.-", "activity": "", "evidence": [ { "id": "Q3ZBY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBY7" } ] }, { "ec_number": "1.14.19.17", "activity": "", "evidence": [ { "id": "Q3ZBY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBY7" } ] } ] }, { "uniprot_ac": "Q3ZC07", "gene_name": "ACTC1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q3ZC07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZC07" } ] } ] }, { "uniprot_ac": "Q5E9F2", "gene_name": "HMOX1", "activity": [ { "ec_number": "1.14.14.18", "activity": "heme b + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = biliverdin IXalpha + CO + Fe(2+) + 3 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+).", "evidence": [ { "id": "Q5E9F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9F2" } ] }, { "ec_number": "1.14.14.18", "activity": "", "evidence": [ { "id": "Q5E9F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9F2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.14.18", "ec_name": "heme b + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = biliverdin IXalpha + CO + Fe(2+) + 3 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+).", "evidence": [ { "id": "1.14.14.18", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.18" }, { "id": "1.14.14.18", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.14.18" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 26, "end_pos": 28 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NZQ6-1", "uniprot_ac": "A0ABI0NZQ6", "uniprot_id": "A0ABI0NZQ6_BOVIN", "mass": { "chemical_mass": 75042.0, "monoisotopic_mass": 75042.0 }, "refseq": {}, "gene_names": [ { "name": "SCNN1D", "type": "recommended", "evidence": [ { "id": "A0ABI0NZQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZQ6" } ] } ], "protein_names": [ { "name": "Sodium channel epithelial 1 subunit delta", "type": "synonym", "evidence": [ { "id": "A0ABI0NZQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZQ6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "This is one of the three pore-forming subunits of the heterotrimeric epithelial sodium channel (ENaC), a critical regulator of sodium balance and fluid homeostasis. ENaC operates in epithelial tissues, where it mediates the electrodiffusion of sodium ions from extracellular fluid through the apical membrane of cells, with water following osmotically. It plays a key role in maintaining sodium homeostasis through electrogenic sodium reabsorption in the kidneys. Additionally, ENaC is essential for airway surface liquid homeostasis, which is crucial for proper mucus clearance.", "evidence": [ { "database": "UniProtKB", "id": "F1MY57", "url": "https://www.uniprot.org/uniprotkb/F1MY57#function" }, { "database": "UniProtKB", "id": "ARBA00049941", "url": "https://www.uniprot.org/uniprotkb/ARBA00049941#function" }, { "database": "UniProtKB", "id": "A0ABI0NWM9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWM9#function" }, { "database": "UniProtKB", "id": "A0ABI0NZQ6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZQ6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZQ6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZQ6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SCNN1D", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZQ6", "locus": { "chromosome": "16", "start_pos": 51229755, "end_pos": 51236428, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017674", "url": "https://www.ensembl.org/id/ENSBTAG00000017674" } ] } } ], "crossref": [ { "id": "ENSBTAG00000017674", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017674", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "528813", "url": "https://www.ncbi.nlm.nih.gov/gene/528813", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:528813", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528813", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1MY57", "url": "https://www.orthodb.org/?gene=F1MY57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11690:SF132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11690:SF132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00858", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00858", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9730628", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9730628", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NWM9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWM9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZQ6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MY57", "url": "https://www.uniprot.org/uniprotkb/F1MY57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MY57-1", "url": "https://www.uniprot.org/uniprotkb/F1MY57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMLATEMQAEGTGQTVGGGPGTWTCPQASPPTLPEEEHGERLVELHASFRELVTFFCTNSTIHGTIRLVCSSQNRLKTASWGLLLAGALGVLYWQFALLFEQYWRYPVIMTVSVHSERKLFPSVTLCDMNPHRPHLARHHLRVLDDFARESIYSLYRFNFSDSMDALGAEVPGPEPAFHLDRRIRLQRLRPLDGQNRVGFKLCNSTGGDCVERAYSSGVVAAREWYRFHYINILALLPAAHEDSHGSHFVFSCRYDDRDCHAQHFQTSHHPTYGSCYTFNGVWAAQRPGVTHRISLVLRAEQLDHLPLLSTKAGIKVMIHPQDHTPFLEHQGFSIRPGTETTIDIREDEVHRLGSPYGQCMDSTGSVDVQLLYNTSYTRQACLVSCFQHLMVETCSCGYFFYPLPAGAEYCSYMRHPAWGHCFHHLYQKLKTHQLPCTTRCPRPCRESSYKLSAGTSRWPSSTSADWVLAVLGEPSRRNPWPSSASIKSWPLPLPSSPSRARTEGPTSRSGAQPLSPEPCPSISLAKVNIFYQELNYRTVDETPVYSVSCLLGQGRERGGASTWASAHHCQHPQVPQLLSAMGSLWSLWFGSSVLSVVEVLELLLDAIALTLLLCCRWLCGSRGQPRAATRVHPPSQRPASGPVAADTTSNAPGPGCLHLPRCCRDFSRSLG", "length": 673, "header": "tr|A0ABI0NZQ6-1|A0ABI0NZQ6_BOVIN Isoform 1 of Sodium channel epithelial 1 subunit delta OS=Bos taurus OX=9913 GN=SCNN1D PE=4 SV=1 CANONICAL=A0ABI0NZQ6-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NWM9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZQ6/entry#A0ABI0NWM9-1", "sequence": { "sequence": "MDAHAQGGCSLEMQAEGTGQTVGGGPGTWTCPQASPPTLPEEEHGERLVELHASFRELVTFFCTNSTIHGTIRLVCSSQNRLKTASWGLLLAGALGVLYWQFALLFEQYWRYPVIMTVSVHSERKLFPSVTLCDMNPHRPHLARHHLRVLDDFARESIYSLYRFNFSDSMDALGAEVPGPEPAFHLDRRIRLQRLRPLDGQNRVGFKLCNSTGGDCVERAYSSGVVAAREWYRFHYINILALLPAAHEDSHGSHFVFSCRYDDRDCHAQHFQTSHHPTYGSCYTFNGVWAAQRPGVTHRISLVLRAEQLDHLPLLSTKAGIKVMIHPQDHTPFLEHQGFSIRPGTETTIDIREDEVHRLGSPYGQCMDSTGSVDVQLLYNTSYTRQACLVSCFQHLMVETCSCGYFFYPLPAGAEYCSYMRHPAWGHCFHHLYQKLKTHQLPCTTRCPRPCRESSYKLSAGTSRWPSSTSADWVLAVLGEPSRRNPWPSSASIKSWPLPLPSSPSRARTEGPTSRSGAQPLSPEPCPSISLAKVNIFYQELNYRTVDETPVYSVPQLLSAMGSLWSLWFGSSVLSVVEVLELLLDAIALTLLLCCRWLCGSRGQPRAATRVHPPSQRPASGPVAADTTSNAPGPGCLHLPRCCRDFSRSLG", "length": 651, "header": "tr|A0ABI0NWM9-1|A0ABI0NWM9_BOVIN Computationally mapped isoform of Sodium channel epithelial 1 subunit delta OS=Bos taurus OX=9913 GN=SCNN1D PE=4 SV=1 CANONICAL=A0ABI0NZQ6-1" }, "locus": { "chromosome": "16", "start_pos": 51235484, "end_pos": 51230348, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146458.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146458.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104254.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104254.1" } ] } }, { "isoform_ac": "A0ABI0NZQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZQ6/entry#A0ABI0NZQ6-1", "sequence": { "sequence": "MAMLATEMQAEGTGQTVGGGPGTWTCPQASPPTLPEEEHGERLVELHASFRELVTFFCTNSTIHGTIRLVCSSQNRLKTASWGLLLAGALGVLYWQFALLFEQYWRYPVIMTVSVHSERKLFPSVTLCDMNPHRPHLARHHLRVLDDFARESIYSLYRFNFSDSMDALGAEVPGPEPAFHLDRRIRLQRLRPLDGQNRVGFKLCNSTGGDCVERAYSSGVVAAREWYRFHYINILALLPAAHEDSHGSHFVFSCRYDDRDCHAQHFQTSHHPTYGSCYTFNGVWAAQRPGVTHRISLVLRAEQLDHLPLLSTKAGIKVMIHPQDHTPFLEHQGFSIRPGTETTIDIREDEVHRLGSPYGQCMDSTGSVDVQLLYNTSYTRQACLVSCFQHLMVETCSCGYFFYPLPAGAEYCSYMRHPAWGHCFHHLYQKLKTHQLPCTTRCPRPCRESSYKLSAGTSRWPSSTSADWVLAVLGEPSRRNPWPSSASIKSWPLPLPSSPSRARTEGPTSRSGAQPLSPEPCPSISLAKVNIFYQELNYRTVDETPVYSVSCLLGQGRERGGASTWASAHHCQHPQVPQLLSAMGSLWSLWFGSSVLSVVEVLELLLDAIALTLLLCCRWLCGSRGQPRAATRVHPPSQRPASGPVAADTTSNAPGPGCLHLPRCCRDFSRSLG", "length": 673, "header": "tr|A0ABI0NZQ6-1|A0ABI0NZQ6_BOVIN Isoform 1 of Sodium channel epithelial 1 subunit delta OS=Bos taurus OX=9913 GN=SCNN1D PE=4 SV=1 CANONICAL=A0ABI0NZQ6-1" }, "locus": { "chromosome": "16", "start_pos": 51234328, "end_pos": 51230348, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137983.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137983.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107226.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107226.1" } ] } }, { "isoform_ac": "F1MY57-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZQ6/entry#F1MY57-1", "sequence": { "sequence": "MENGRLMAQVGRPGWGQAKWWAGAPLSLTSQMQAEGTGQTVGGGPGTWTCPQASPPTLPEEEHGERLVELHASFRELVTFFCTNSTIHGTIRLVCSSQNRLKTASWGLLLAGALGVLYWQFALLFEQYWRYPVIMTVSVHSERKLFPSVTLCDMNPHRPHLARHHLRVLDDFARESIYSLYRFNFSDSMDALGAEVPGPEPAFHLDRRIRLQRLRPLDGQNRVGFKLCNSTGGDCVERAYSSGVVAAREWYRFHYINILALLPAAHEDSHGSHFVFSCRYDDRDCHAQHFQTSHHPTYGSCYTFNGVWAAQRPGVTHRISLVLRAEQLDHLPLLSTKAGIKVMIHPQDHTPFLEHQGFSIRPGTETTIDIREDEVHRLGSPYGQCMDSTGSVDVQLLYNTSYTRQACLVSCFQHLMVETCSCGYFFYPLPAGAEYCSYMRHPAWGHCFHHLYQKLKTHQLPCTTRCPRPCRESSYKLSAGTSRWPSSTSADWVLAVLGEPSRRNPWPSSASIKSWPLPLPSSPSRARTEGPTSRSGAQPLSPEPCPSISLAKVNIFYQELNYRTVDETPVYSVPQLLSAMGSLWSLWFGSSVLSVVEVLELLLDAIALTLLLCCRWLCGSRGQPRAATRVHPPSQRPASGPVAADTTSNAPGPGCLHLPRCCRDFSRSLG", "length": 670, "header": "tr|F1MY57-1|A0ABI0NZQ6_BOVIN Computationally mapped isoform of Sodium channel epithelial 1 subunit delta OS=Bos taurus OX=9913 GN=SCNN1D PE=4 SV=5 CANONICAL=A0ABI0NZQ6-1" }, "locus": { "chromosome": "16", "start_pos": 51233897, "end_pos": 51230348, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023511.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023511.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023511.7", "url": "https://www.ensembl.org/id/ENSBTAP00000023511.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 508, "start_aa": "Thr", "end_pos": 508, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr508", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:528813", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528813", "resource": "KEGG Pathway" }, { "id": "R-BTA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" }, { "id": "R-BTA-9730628", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9730628", "resource": "Reactome", "description": "Sensory perception of salty taste" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZQ6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZQ6" } ], "pmid": "" }, { "name": "sodium channel complex", "id": "GO:0034706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034706", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZQ6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZQ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZQ6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZQ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ligand-gated sodium channel activity", "id": "GO:0015280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015280", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZQ6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "34963", "name": "", "equation": "Na(+)(in) = Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P35526-1" ], "evidence": [ { "id": "34963", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34963" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "P35526", "gene_name": "CLIC5", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "P35526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35526" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 508 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 375, "end_pos": 377 }, { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NWE4-1", "uniprot_ac": "A0ABI0NWE4", "uniprot_id": "A0ABI0NWE4_BOVIN", "mass": { "chemical_mass": 77136.0, "monoisotopic_mass": 77136.0 }, "refseq": {}, "gene_names": [ { "name": "POMGNT1", "type": "recommended", "evidence": [ { "id": "A0ABI0NWE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4" } ] } ], "protein_names": [ { "name": "Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase", "type": "recommended", "evidence": [ { "id": "A0ABI0NWE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "A0ABI0NWE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4/entry#names_and_taxonomy" } ] }, { "name": "POMGnT1", "type": "synonym", "evidence": [ { "id": "A0ABI0NWE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LMT5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMT5#function" }, { "database": "UniProtKB", "id": "RU368119", "url": "https://www.uniprot.org/uniprotkb/RU368119#function" } ] }, { "annotation": "Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S2V9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2V9#function" }, { "database": "UniProtKB", "id": "RU368119", "url": "https://www.uniprot.org/uniprotkb/RU368119#function" }, { "database": "UniProtKB", "id": "A0AAA9TSX3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSX3#function" }, { "database": "UniProtKB", "id": "F6QJC0", "url": "https://www.uniprot.org/uniprotkb/F6QJC0#function" }, { "database": "UniProtKB", "id": "A0A3Q1MF72", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF72#function" }, { "database": "UniProtKB", "id": "A0ABI0NWE4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWE4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "POMGNT1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4", "locus": { "chromosome": "3", "start_pos": 99893598, "end_pos": 99869871, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013322", "url": "https://www.ensembl.org/id/ENSBTAG00000013322" } ] } } ], "crossref": [ { "id": "ENSBTAG00000013322", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013322", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02514", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02514", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13937", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13937", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039474", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039474", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052463", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052463", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LMT5", "url": "https://www.orthodb.org/?gene=A0A3Q1LMT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MF72", "url": "https://www.orthodb.org/?gene=A0A3Q1MF72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46396:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46396:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "11456", "url": "https://www.rhea-db.org/rhea/11456", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54128", "url": "https://www.rhea-db.org/rhea/54128", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LMT5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MF72", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MF72-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S2V9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S2V9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSX3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSX3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWE4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWE4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QJC0", "url": "https://www.uniprot.org/uniprotkb/F6QJC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QJC0-1", "url": "https://www.uniprot.org/uniprotkb/F6QJC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDCCRHGLARTVVTPPYDMDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEASEDLEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAQEQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVLGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRKSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKDAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLRIWDLDVRGNHRGLWRLFRKKNHFLVVGVPASPYSMKKPPSITPIFLESPPKEEGGPGAAEQT", "length": 678, "header": "tr|A0ABI0NWE4-1|A0ABI0NWE4_BOVIN Isoform 1 of Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase OS=Bos taurus OX=9913 GN=POMGNT1 PE=3 SV=1 CANONICAL=A0ABI0NWE4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMT5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4/entry#A0A3Q1LMT5-1", "sequence": { "sequence": "MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEASEDLEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAQEQGRGIHVIVLNQATDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVLGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRKSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKDAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLRIWDLDVRGNHRGLWRLFRKKNHFLVVGVPASPYSMKKPPSITPIFLESPPKEEGGPGAAEQT", "length": 622, "header": "tr|A0A3Q1LMT5-1|A0ABI0NWE4_BOVIN Computationally mapped isoform of Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase OS=Bos taurus OX=9913 GN=POMGNT1 PE=3 SV=1 CANONICAL=A0ABI0NWE4-1" }, "locus": { "chromosome": "3", "start_pos": 99892998, "end_pos": 99885044, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071488.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071488.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058221.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058221.1" } ] } }, { "isoform_ac": "A0A3Q1MF72-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4/entry#A0A3Q1MF72-1", "sequence": { "sequence": "MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEASEDLEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAQEQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVLGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPVSGALGSESRTLPQLGKRPQERMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPVSSKDKTLGPRWGNFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRKSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLRIWDLDVRGNHRGLWRLFRKKNHFLVVGVPASPYSMKKPPSITPIFLESPPKEEGGPGAAEQT", "length": 637, "header": "tr|A0A3Q1MF72-1|A0ABI0NWE4_BOVIN Computationally mapped isoform of Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase OS=Bos taurus OX=9913 GN=POMGNT1 PE=3 SV=1 CANONICAL=A0ABI0NWE4-1" }, "locus": { "chromosome": "3", "start_pos": 99892998, "end_pos": 99885044, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083947.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083947.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067559.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067559.1" } ] } }, { "isoform_ac": "A0AAA9S2V9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4/entry#A0AAA9S2V9-1", "sequence": { "sequence": "MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEASEDLEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAQEQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRKSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKDAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLRIWDLDVRGNHRGLWRLFRKKNHFLVVGVPASPYSMKKPPSITPIFLESPPKEEGGPGAAEQT", "length": 627, "header": "tr|A0AAA9S2V9-1|A0ABI0NWE4_BOVIN Computationally mapped isoform of Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase OS=Bos taurus OX=9913 GN=POMGNT1 PE=3 SV=1 CANONICAL=A0ABI0NWE4-1" }, "locus": { "chromosome": "3", "start_pos": 99892998, "end_pos": 99885044, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102160.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102160.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077627.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077627.1" } ] } }, { "isoform_ac": "A0AAA9TSX3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4/entry#A0AAA9TSX3-1", "sequence": { "sequence": "MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEASEDLEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAQEQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVLGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRKSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKDAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLRIWDLDVRGNHRGLWRLFRKKNHFLVVGVPASPYSMKKPPSITPIFLESPPKEEGGPGAAEQT", "length": 632, "header": "tr|A0AAA9TSX3-1|A0ABI0NWE4_BOVIN Computationally mapped isoform of Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase OS=Bos taurus OX=9913 GN=POMGNT1 PE=3 SV=1 CANONICAL=A0ABI0NWE4-1" }, "locus": { "chromosome": "3", "start_pos": 99892998, "end_pos": 99885044, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127455.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127455.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100160.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100160.1" } ] } }, { "isoform_ac": "A0ABI0NWE4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4/entry#A0ABI0NWE4-1", "sequence": { "sequence": "MDCCRHGLARTVVTPPYDMDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEASEDLEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAQEQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVLGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRKSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKDAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLRIWDLDVRGNHRGLWRLFRKKNHFLVVGVPASPYSMKKPPSITPIFLESPPKEEGGPGAAEQT", "length": 678, "header": "tr|A0ABI0NWE4-1|A0ABI0NWE4_BOVIN Isoform 1 of Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase OS=Bos taurus OX=9913 GN=POMGNT1 PE=3 SV=1 CANONICAL=A0ABI0NWE4-1" }, "locus": { "chromosome": "3", "start_pos": 99892998, "end_pos": 99881321, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149850.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149850.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104122.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104122.1" } ] } }, { "isoform_ac": "F6QJC0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4/entry#F6QJC0-1", "sequence": { "sequence": "MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEASEDLEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAQEQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRKSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKDAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLRIWDLDVRGNHRGLWRLFRKKNHFLVVGVPASPYSMKKPPSITPIFLESPPKEEGGPGAAEQT", "length": 640, "header": "tr|F6QJC0-1|A0ABI0NWE4_BOVIN Computationally mapped isoform of Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase OS=Bos taurus OX=9913 GN=POMGNT1 PE=3 SV=2 CANONICAL=A0ABI0NWE4-1" }, "locus": { "chromosome": "3", "start_pos": 99892998, "end_pos": 99885044, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043096.4", "url": "https://www.ensembl.org/id/ENSBTAT00000043096.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040690.3", "url": "https://www.ensembl.org/id/ENSBTAP00000040690.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 486, "start_aa": "Thr", "end_pos": 486, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr486", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWE4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWE4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWE4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4" } ], "pmid": "" }, { "name": "alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity", "id": "GO:0003827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003827", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWE4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4" } ], "pmid": "" }, { "name": "acetylglucosaminyltransferase activity", "id": "GO:0008375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008375", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWE4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWE4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4" } ], "pmid": "" }, { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWE4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11456", "name": "", "equation": "N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NWE4-1" ], "evidence": [ { "id": "11456", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11456" } ] }, { "id": "54128", "name": "", "equation": "3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl)-L-threonyl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NWE4-1", "Q5EAB6-1" ], "evidence": [ { "id": "54128", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54128" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0ABI0NWE4", "gene_name": "POMGNT1", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0ABI0NWE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4" } ] }, { "ec_number": "2.4.1.101", "activity": "N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+).", "evidence": [ { "id": "A0ABI0NWE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4" } ] }, { "ec_number": "2.4.1.101", "activity": "", "evidence": [ { "id": "A0ABI0NWE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4" } ] } ] }, { "uniprot_ac": "Q5EAB6", "gene_name": "POMGNT1", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "Q5EAB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NWE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWE4" }, { "id": "PF15711", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15711" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ILEI/PANDER", "eco_id": "ECO_0000259", "start_pos": 147, "end_pos": 236, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.101", "ec_name": "N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+).", "evidence": [ { "id": "2.4.1.101", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.101" }, { "id": "2.4.1.101", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.101" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 486 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 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"categories": [ "Protein" ] }, { "id": "A0AAA9THM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMC2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMC2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXB0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXB0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMC4", "url": "https://www.uniprot.org/uniprotkb/E1BMC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMC4-1", "url": "https://www.uniprot.org/uniprotkb/E1BMC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQQIPTGYLFYIWFARMVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFSHLKEVLNNVTELSEIEPNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPSHEGTAEGMENMADAVTHARFVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKSAEHTLVDMVQLLFTRLPQFKEEPKNYMGTNMKKISPCLLNKLELSSGEQTKALNQLERLKMRAGGMSDSSKWKKQKRSPRAPRHMTKVIPGSEQPTSSGTTLSSNLSGGMPFIDVPTPISSASSETASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTVAESGSSELGVPEQPEPQEGAHVEKAQSTSVESIPEVLEECSSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPIAQCQTLLGLIKDEMCRHLFQLLSVERLNLYAASLRVCFLLFESMREHLKFQLEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWHIPSFVTELYINYDCDYYCSNLFEDLTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNNLIQQERKEAARPGYEAVDGTREANSTERAASDGKATGMAPDIAGLNLPGGGRLPAEHGKPGCSDLEEAGDSGADKKFTRKPPRFSCILPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTEHWRNCNGSPFANSDACFALAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPAGSYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPTVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAMAEVEDFVDPNGKICLQREETPSNRGESTVLSFVSWLTLSGTEQSSVRGPSTENQEAKRMALDCIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISGQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDIDNSKPGPGPSRPGPSPLVNQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGYKSQEKRGKSHKYDNKGNRFKKKSKEGSVLRRPRTSSQHAARGGHSDDDEDEGVPASYHTVSLQLLDLMHTLHTRAASIYSSWAEEQRHLETGGRKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGSPSALWEITWERIDCFLPHLRDELFKQTVIQDPVPMEPHAPKPLASAHLTPAAGDTRSPGHPPPPEMPSELGTRDFEKPEGPRPANSSSSGSPVASSPSRLSPTPDGPPPLAQSPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPMPTSEVN", "length": 1898, "header": "tr|A0ABI0NXB0-1|A0ABI0NXB0_BOVIN Isoform 1 of Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Bos taurus OX=9913 GN=GBF1 PE=4 SV=1 CANONICAL=A0ABI0NXB0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SYT8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXB0/entry#A0AAA9SYT8-1", "sequence": { "sequence": "MQQIPTGYLFYIWFARMVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFSHLKEVLNNVTELSEIEPNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPSHEGTAEGMENMADAVTHARFVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKSAEHTLVDMVQLLFTRLPQFKEEPKNYMGTNMKKLKMRAGGMSDSSKWKKQKRSPRAPRHMTKVIPGSEQPTSSGTTLSSNLSGGMPFIDVPTPISSASSETASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTVAESGSSELGVPEQPEPQEGAHVEKAQSTSVESIPEVLEECSSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPIAQCQTLLGLIKDEMCRHLFQLLSVERLNLYAASLRVCFLLFESMREHLKFQLEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWHIPSFVTELYINYDCDYYCSNLFEDLTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNNLIQQERKEAARPGYEAVDGTREANSTERAASDGKATGMAPDIAGLNLPGGGRLPAEHGKPGCSDLEEAGDSGADKKFTRKPPRFSCILPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTEHWRNCNGSPFANSDACFALAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPAGSYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPTVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAMAEVEDFVDPNGKICLQREETPSNRGESTVLSFVSWLTLSGTEQSSVRGPSTENQEAKRMALDCIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISGQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDIDNSKPGPGPSRPGPSPLVNQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGYKSQEKRGKSHKYDNKGNRFKKKSKEGSVLRRPRTSSQHAARGGHSDDDEDEGVPASYHTVSLQVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGSPSALWEITWERIDCFLPHLRDELFKQTVIQDPVPMEPHAPKPLASAHLTPAAGDTRSPGHPPPPEMPSELGTRDFEKPEGPRPANSSSSGSPVASSPSRLSPTPDGPPPLAQSPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPMPTSEVN", "length": 1779, "header": "tr|A0AAA9SYT8-1|A0ABI0NXB0_BOVIN Computationally mapped isoform of Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Bos taurus OX=9913 GN=GBF1 PE=4 SV=2 CANONICAL=A0ABI0NXB0-1" }, "locus": { "chromosome": "26", "start_pos": 23012384, "end_pos": 22900456, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088118.2", "url": "https://www.ensembl.org/id/ENSBTAT00000088118.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091618.2", "url": "https://www.ensembl.org/id/ENSBTAP00000091618.2" } ] } }, { "isoform_ac": "A0AAA9THM1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXB0/entry#A0AAA9THM1-1", "sequence": { "sequence": "MQQIPTGYLFYIWFARMVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFSHLKEVLNNVTELSEIEPNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPSHEGTAEGMENMADAVTHARFVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKSAEHTLVDMVQLLFTRLPQFKEEPKNYMGTNMKKLKMRAGGMSDSSKWKKQKRSPRAPRHMTKVIPGSEQPTSSGTTLSSNLSGGMPFIDVPTPISSASSETASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTVAESGSSELGVPEQPEPQEGAHVEKAQSTSVESIPEVLEECSSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPIAQCQTLLGLIKDEMCRHLFQNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNNLIQQERKEAARPGYEAVDGTREANSTERAASDGKATGMAPDIAGLNLPGGGRLPAEHGKPGCSDLEEAGDSGADKKFTRKPPRFSCILPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTEHWRNCNGSPFANSDACFALAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPAGSYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPTVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAMAEVEDFVDPNGKICLQREETPSNRGESTVLSFVSWLTLSGTEQSSVRGPSTENQEAKRMALDCIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISGQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDIDNSKPGPGPSRPGPSPLVNQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGYKSQEKRGKSHKYDNKGNRFKKKSKEGSVLRRPRTSSQHAARGGHSDDDEDEGVPASYHTVSLQLLDLMHTLHTRAASIYSSWAEEQRHLETGGRKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGSPSALWEITWERIDCFLPHLRDELFKQTVIQDPVPMEPHAPKPLASAHLTPAAGDTRSPGHPPPPEMPSELGTRDFEKPEGPRPANSSSSGSPVASSPSRLSPTPDGPPPLAQSPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPMPTSEVN", "length": 1775, "header": "tr|A0AAA9THM1-1|A0ABI0NXB0_BOVIN Computationally mapped isoform of Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Bos taurus OX=9913 GN=GBF1 PE=4 SV=2 CANONICAL=A0ABI0NXB0-1" }, "locus": { "chromosome": "26", "start_pos": 23012384, "end_pos": 22900456, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113008.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113008.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095709.2", "url": "https://www.ensembl.org/id/ENSBTAP00000095709.2" } ] } }, { "isoform_ac": "A0AAA9TMC2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXB0/entry#A0AAA9TMC2-1", "sequence": { "sequence": "MGFSSRFARMVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFSHLKEVLNNVTELSEIEPNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPSHEGTAEGMENMADAVTHARFVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKSAEHTLVDMVQLLFTRLPQFKEEPKNYMGTNMKKLKMRAGGMSDSSKWKKQKRSPRAPRHMTKVIPGSEQPTSSGTTLSSNLSGGMPFIDVPTPISSASSETASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTVAESGSSELGVPEQPEPQEGAHVEKAQSTSVESIPEVLEECSSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPIAQCQTLLGLIKDEMCRHLFQLLSVERLNLYAASLRVCFLLFESMREHLKFQLEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWHIPSFVTELYINYDCDYYCSNLFEDLTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNNLIQQERKEAARPGYEAVDGTREANSTERAASDGKATGMAPDIAGLNLPGGGRLPAEHGKPGCSDLEEAGDSGADKKFTRKPPRFSCILPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTEHWRNCNGSPFANSDACFALAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPAGSYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPTVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAMAEVEDFVDPNGKICLQREETPSNRGESTVLSFVSWLTLSGTEQSSVRGPSTENQEAKRMALDCIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISGQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDIDNSKPGPGPSRPGPSPLVNQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGYKSQEKRGKSHKYDNKGNRFKKKSKEGSVLRRPRTSSQHAARGGHSDDDEDEGVPASYHTVSLQLLDLMHTLHTRAASIYSSWAEEQRHLETGGRKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGSPSALWEITWERIDCFLPHLRDELFKQTVIQDPVPMEPHAPKPLASAHLTPAAGDTRSPGHPPPPEMPSELGTRDFEKPEGPRPANSSSSGSPVASSPSRLSPTPDGPPPLAQSPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPMPTSEVN", "length": 1866, "header": "tr|A0AAA9TMC2-1|A0ABI0NXB0_BOVIN Computationally mapped isoform of Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Bos taurus OX=9913 GN=GBF1 PE=4 SV=1 CANONICAL=A0ABI0NXB0-1" }, "locus": { "chromosome": "26", "start_pos": 23012384, "end_pos": 22898944, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093725.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093725.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097466.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097466.1" } ] } }, { "isoform_ac": "A0ABI0NXB0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXB0/entry#A0ABI0NXB0-1", "sequence": { "sequence": "MQQIPTGYLFYIWFARMVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFSHLKEVLNNVTELSEIEPNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPSHEGTAEGMENMADAVTHARFVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKSAEHTLVDMVQLLFTRLPQFKEEPKNYMGTNMKKISPCLLNKLELSSGEQTKALNQLERLKMRAGGMSDSSKWKKQKRSPRAPRHMTKVIPGSEQPTSSGTTLSSNLSGGMPFIDVPTPISSASSETASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTVAESGSSELGVPEQPEPQEGAHVEKAQSTSVESIPEVLEECSSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPIAQCQTLLGLIKDEMCRHLFQLLSVERLNLYAASLRVCFLLFESMREHLKFQLEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWHIPSFVTELYINYDCDYYCSNLFEDLTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNNLIQQERKEAARPGYEAVDGTREANSTERAASDGKATGMAPDIAGLNLPGGGRLPAEHGKPGCSDLEEAGDSGADKKFTRKPPRFSCILPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTEHWRNCNGSPFANSDACFALAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPAGSYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPTVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAMAEVEDFVDPNGKICLQREETPSNRGESTVLSFVSWLTLSGTEQSSVRGPSTENQEAKRMALDCIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISGQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDIDNSKPGPGPSRPGPSPLVNQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGYKSQEKRGKSHKYDNKGNRFKKKSKEGSVLRRPRTSSQHAARGGHSDDDEDEGVPASYHTVSLQLLDLMHTLHTRAASIYSSWAEEQRHLETGGRKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGSPSALWEITWERIDCFLPHLRDELFKQTVIQDPVPMEPHAPKPLASAHLTPAAGDTRSPGHPPPPEMPSELGTRDFEKPEGPRPANSSSSGSPVASSPSRLSPTPDGPPPLAQSPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPMPTSEVN", "length": 1898, "header": "tr|A0ABI0NXB0-1|A0ABI0NXB0_BOVIN Isoform 1 of Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Bos taurus OX=9913 GN=GBF1 PE=4 SV=1 CANONICAL=A0ABI0NXB0-1" }, "locus": { "chromosome": "26", "start_pos": 23012384, "end_pos": 22900456, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136082.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136082.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105806.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105806.1" } ] } }, { "isoform_ac": "E1BMC4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXB0/entry#E1BMC4-1", "sequence": { "sequence": "MVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFSHLKEVLNNVTELSEIEPNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPSHEGTAEGMENMADAVTHARFVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKSAEHTLVDMVQLLFTRLPQFKEEPKNYMGTNMKKISPCLLNKLELSSGEQTKALNQLERVLLFKNLKLKMRAGGMSDSSKWKKQKRSPRAPRHMTKVIPGSEQPTSSGTTLSSNLSGGMPFIDVPTPISSASSETASAVVSPSTDSGLEFSSQTTSKEDLTDLEQPGSPGYSTVAESGSSELGVPEQPEPQEGAHVEKAQSTSVESIPEVLEECSSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPIAQCQTLLGLIKDEMCRHLFQLLSVERLNLYAASLRVCFLLFESMREHLKFQLEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWHIPSFVTELYINYDCDYYCSNLFEDLTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNNLIQQERKEAARPGYEAVDGTREANSTERAASDGKATGMAPDIAGLNLPGGGRLPAEHGKPGCSDLEEAGDSGADKKFTRKPPRFSCILPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTEHWRNCNGSPFANSDACFALAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPAGSYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPTVFGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAMAEVEDFVDPNGKICLQREETPSNRGESTVLSFVSWLTLSGTEQSSVRGPSTENQEAKRMALDCIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERAVVGLLRLAIRLLRREEISGQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDIDNSKPGPGPSRPGPSPLVNQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGYKSQEKRGKSHKYDNKGNRFKKKSKEGSVLRRPRTSSQHAARGGHSDDDEDEGVPASYHTVSLQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETGGRKIEADSRTLWAHCWCPLLQGIACLCCDARRQVRMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGSPSALWEITWERIDCFLPHLRDELFKQTVIQDPVPMEPHAPKPLASAHLTPAAGDTRSPGHPPPPEMPSELGTRDFEKPEGPRPANSSSSGSPVASSPSRLSPTPDGPPPLAQSPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPMPTSEVN", "length": 1894, "header": "tr|E1BMC4-1|A0ABI0NXB0_BOVIN Computationally mapped isoform of Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Bos taurus OX=9913 GN=GBF1 PE=4 SV=2 CANONICAL=A0ABI0NXB0-1" }, "locus": { "chromosome": "26", "start_pos": 23012384, "end_pos": 22901703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061619.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061619.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053253.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053253.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1835, "start_aa": "Thr", "end_pos": 1835, "end_aa": "Thr", "residue": 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"IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:525199", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525199", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PFMCESC", "url": "https://omabrowser.org/oma/group/PFMCESC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BIC9", "url": "https://www.orthodb.org/?gene=E1BIC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NYU0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYU0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIC9", "url": "https://www.uniprot.org/uniprotkb/E1BIC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIC9-1", "url": "https://www.uniprot.org/uniprotkb/E1BIC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESGAVLLESKSSPINLLHEMHQLRLLGHLCDVTVSVEYQGVREEFMAHKAVLAATSKFFKEVFLNEKTVDGARTNVYLDEVQVADFASFLEFVYTAKVQVEEDRVQRMLEMAEKLKCLDLSETCFQLKKQMLESVLLELQNFSESQEAEGSSGAQVTAALAPEAWAGMAPDGPLANGVASSLDPPAERIGNGLLPDLPPRKSREKPDKRKEVAKPPYPKLRRASGRLAGRKVFVEIPKKKYTRRLREQQKSVEQDMGGCGGPREPSPEALENEKEAVTKDEEDSGAGAGVEAAPPKVGRGEEGDEEEEEGEEGPGRRRSNFQCTRCEKAFLYEKSFLKHVRLHHGVATEVVHRCDTCGQTFANRCNLKGHQRHVHSSERHFPCELCGKKFKRKKDVKRHVVQVHEGGGERHQCQQCGKGLSSKTALRLHERTHTGHKPYGCSECPATFSQPSALKTHLRIHTGEKPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQLNALQRHHRIHTGEKPFMCNACGRAFTDKSTLRRHTSIHDKTTPWKSFLVIVDGSPKNGDGHKTEQPDDEYAPSKLSDKLLSFAENGHFHNLATVQGSMPAMHEDSPADPACKSDGPVGSQDTLLATAISELSELTPQTERPTLRSLTHVD", "length": 714, "header": "tr|A0ABI0NYU0-1|A0ABI0NYU0_BOVIN Isoform 1 of GDNF-inducible zinc finger protein 1 OS=Bos taurus OX=9913 GN=GZF1 PE=3 SV=1 CANONICAL=A0ABI0NYU0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NYU0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0/entry#A0ABI0NYU0-1", "sequence": { "sequence": "MESGAVLLESKSSPINLLHEMHQLRLLGHLCDVTVSVEYQGVREEFMAHKAVLAATSKFFKEVFLNEKTVDGARTNVYLDEVQVADFASFLEFVYTAKVQVEEDRVQRMLEMAEKLKCLDLSETCFQLKKQMLESVLLELQNFSESQEAEGSSGAQVTAALAPEAWAGMAPDGPLANGVASSLDPPAERIGNGLLPDLPPRKSREKPDKRKEVAKPPYPKLRRASGRLAGRKVFVEIPKKKYTRRLREQQKSVEQDMGGCGGPREPSPEALENEKEAVTKDEEDSGAGAGVEAAPPKVGRGEEGDEEEEEGEEGPGRRRSNFQCTRCEKAFLYEKSFLKHVRLHHGVATEVVHRCDTCGQTFANRCNLKGHQRHVHSSERHFPCELCGKKFKRKKDVKRHVVQVHEGGGERHQCQQCGKGLSSKTALRLHERTHTGHKPYGCSECPATFSQPSALKTHLRIHTGEKPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQLNALQRHHRIHTGEKPFMCNACGRAFTDKSTLRRHTSIHDKTTPWKSFLVIVDGSPKNGDGHKTEQPDDEYAPSKLSDKLLSFAENGHFHNLATVQGSMPAMHEDSPADPACKSDGPVGSQDTLLATAISELSELTPQTERPTLRSLTHVD", "length": 714, "header": "tr|A0ABI0NYU0-1|A0ABI0NYU0_BOVIN Isoform 1 of GDNF-inducible zinc finger protein 1 OS=Bos taurus OX=9913 GN=GZF1 PE=3 SV=1 CANONICAL=A0ABI0NYU0-1" }, "locus": { "chromosome": "13", "start_pos": 42035731, "end_pos": 42030334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136692.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136692.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105245.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105245.1" } ] } }, { "isoform_ac": "E1BIC9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0/entry#E1BIC9-1", "sequence": { "sequence": "MESGAVLLESKSSPINLLHEMHQLRLLGHLCDVTVSVEYQGVREEFMAHKAVLAATSKFFKEVFLNEKTVDGARTNVYLDEVQVADFASFLEFVYTAKVQVEEDRVQRMLEMAEKLKCLDLSETCFQLKKQMLESVLLELQNFSESQEAEGSSGAQVTAALAPEAWAGMAPDGPLANGVASSLDPPAERIGNGLLPDLPPRKSREKPDKRKEVAKPPYPKLRRASGRLAGRKVFVEIPKKKYTRRLREQQKSVEQDMGGCGGPREPSPEALENEKEAVTKDEEDSGAGAGVEAAPPKVGRGEEGDEEEEEGEEGPGRRRSNFQCTRCEKAFLYEKSFLKHVRLHHGVATEVVHRCDTCGQTFANRCNLKGHQRHVHSSERHFPCELCGKKFKRKKDVKRHVVQVHEGGGERHQCQQCGKGLSSKTALRLHERTHTGHKPYGCSECPATFSQPSALKTHLRIHTGEKPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQLNALQRHHRIHTGEKPFMCNACGRAFTDKSTLRRHTSIHDKTTPWKSFLVIVDGSPKNGDGHKTEQPDDEYAPSKLSDKLLSFAENGHFHNLATVQGSMPAMHEDSPADPACKSDGPVGSQDTLLATAISELSELTPQTEPGPHSSAL", "length": 711, "header": "tr|E1BIC9-1|A0ABI0NYU0_BOVIN Computationally mapped isoform of GDNF-inducible zinc finger protein 1 OS=Bos taurus OX=9913 GN=GZF1 PE=3 SV=2 CANONICAL=A0ABI0NYU0-1" }, "locus": { "chromosome": "13", "start_pos": 42035717, "end_pos": 42030334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046451.6", "url": "https://www.ensembl.org/id/ENSBTAT00000046451.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043751.3", "url": "https://www.ensembl.org/id/ENSBTAP00000043751.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:525199", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:525199", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z5W4-1", "protein_name": "GDNF inducible zinc finger protein 1", "gene_name": "GZF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMEKKKILMKSKVAAPNLLRALHSLYQFGHLCDVTVHTQHLGIQEEFLVHKAVLAASSNYFKGLFLHDGMLDTKNCTVTLQDIYTEEFTSFLEFVYTAEVEIEAGKLQRMKEIAERLECKDLLDICEEVRAEGKKGLDLSLHLKSQLCENGVPQWPCIQQEENRKLSSCSQVVAVPMQRKLWERQKCNKLLAGYELTEGQPANLEQEGTAFPQQKSRTIELPKCDRTDNRGRFGMDVISLEQRNTHSPVSQTVSKEACVVIRDMLSEQWEDGNSLISDLSSKTKRRRSLRRVAKVLPEIACEKCNESFHVIKQYQLHMELKHGVNLSVKYSCNMCEQLFSSHQNLRQHCLTVHSAERGFSCVFCDKKFKHQKDRNDHIQRVHEKQRDPQACPYCDKVISSKCGLTVHIRTHTGEKPYKCECCPASFAHRSAYKTHIRKIHESGQERKLMPVYWMVVPPTHRPNAASKDSDREIWDGMSEAELEKSAMHKESASCEEEPARPPVTQTDCSELQEQKQKCTEAQRGTETLSEEGNEAEGEKSVKGEEEGVHDAEYSDVEDSRDNDEACTEEDDEDDECSNEKCAEECESAEEFKIKKVNRSGVNKKSAYVIRCNKCNEQFVSRKKYVDHCRDIHQCLPGKVYQCDICSKSFASYNSWKEHRACVHTDERQFACSLCNATFKRKRDVRTHYVRKHEGRVKRPLCSVCGKILSSRTALVFHMRTHTGEKPYECGICHSKFAQPSQLKIHTRSHTGEKPYVCEDCGACFADKGKLTGHKRTHTGERLFKCDVCGKHFATNEYLKCHKRCHMGAKPYKCEVCGKTFGLRASLAQHSNVHAETRPYFCEQCGKTFTQQGALRRHQRIHTGEKPYKCRACERTFTDMSTLRRHVSIHDRNAHWRSFLIDLTTKKTHNWSKIETFSGACMGEDSVPEIWSVDRAFCREKKDGK", "length": 944 }, "evidence": [ { "id": "A0ABI0NYU0", "url": "https://omabrowser.org/oma/group/A0ABI0NYU0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7JTP0-1", "protein_name": "GDNF-inducible zinc finger protein 1", "gene_name": "Gzf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQATDPGLTTSQSPCPKSRKSTQHNARNRLCSWTCARSAFLACRGRGPSGGGAGSWQPFRRPRDPLFLRGLFQGAGPAEAPTARRKMESGTVLLESKSSPLHLLHEMHELRLLGHLCDVTVSVEYQGVCEDFMAHKAVLAATSKFFKEVFLNEKRVDGTRTNVCLKEVQVVDFASFLEFVYTARVQVEEDRVQRMLEVAEKLKCWDLSETCFHLKKQMLESVLLESQNFFVSQEVEASSGPHVSVTPSSKASIPGEEAHSSGLVDTSDYLIERFDNDLLPEMPSRKCKEKLDKKKDVAKPPYPKIRRPSGRLAGRKVFVEIPKKKYTRRLREQQRSAEEAAENDRCSQNQSPDTERLETEPASKSEACSSGVKLEESQQKVEGEKEEEGKDGEKKSNFRCTVCEKAFLYEKSYLKHIRHHHGVATEVVYQCDTCGQTFANRCNLKSHQRHVHSSERHFPCEMCAKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKTSLRMHERTHTGDRPYGCTKCEAKFSQPSALKTHMRIHTGERPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCLRTFAQRNSLYQHAKIHTGERPYCCDQCGKQFTQVNALQRHHRIHTGEKPFMCNACGRTFTDKSTLRRHTSIHDKNTPWKSFLVIVDGSPKNDGHTEQPDDEYASTKLSDRLLSFGENSHFNNLLEVQSNVPAMQENSSTDTACKAVVSQDALLTTTINELGELTPQPGSMTTHLPSLTNME", "length": 787 }, "evidence": [ { "id": "A0ABI0NYU0", "url": "https://omabrowser.org/oma/group/A0ABI0NYU0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZUU2-1", "protein_name": "GDNF-inducible zinc finger protein 1", "gene_name": "Gzf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESGTVLLESKSSPLNLLHEMHELRLLGHLCDVTVIVDYQGVREDFMAHKAVLAATSKFFKEVFLNEKRADGTRTNVYLSEVQVVDFASFLEFVYTARVRVKEDRVQQMLEVAEKLKCLDLSETCLQLKKQMLESVLLELQNFSESQEVEASSGPQVSVTPSSKASVPAGEDAHSNGLVDSSDYPIERLGNGLSPETPSKKCKEKLDKKKDVAKPPFPKIRRASGRLAGKKVFVEIPKKKYTRRLREQQKSAEEAAKNDKCPQDQSPDNERVEAEPASKSEACPASVEREESLQKVEGEKEEEEGKDGEEKKKSNFQCTVCDKAFLYEKSFLKHIKYHHGVATEVVYRCDTCGQTFANRCNLKSHQRHVHSSERHFPCEMCAKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKTALRLHERTHTGDKPYGCTKCDAKFSQPSALKTHLRVHTGERPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCLRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQVNALQRHHRIHTGEKPYMCNACGRTFTDKSTLRRHTSIHDKNTPWKSFLVIVDGSPKNDEGQKTEQPDEEYASPKLSDRLLSFGENSHFNNLLEVQGNVPAVQENSSTDTACKAVVSQDALLTTSISALGELTPQTVSMPAHLPSLTNME", "length": 707 }, "evidence": [ { "id": "A0ABI0NYU0", "url": "https://omabrowser.org/oma/group/A0ABI0NYU0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4VBD9-1", "protein_name": "GDNF-inducible zinc finger protein 1", "gene_name": "Gzf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESGTVLLESKSSPLNLLHEMHELRLLGHLCDVTVSIENQGVHEDFMAHKAVLAATSKFFKEVFLNEKSADGTRTNVYLNEVQAVDFASFLEFVYTAKVRVEEDRVQQMLEVAEKLKCLDLSETCLQLKKQMLESVLLELQNFSESQEVEASSGPQVSVTPSSKASVPGEDAHSNGLVDSSDYPIERLGNGLSPETPSKKCKEKLDKKKDVAKPPFPKIRRASGRLAGKKVFVEIPKKKYTRRLREQQKSAEEAAENDKCPQDQSPDNERMETEPAAKSEACPASVELEESLQKVEGEKEEEEGKDGEEKKKSNFQCTVCDKAFLYEKSFLKHIKYHHGVATEVVYRCDTCGQTFANRCNLKSHQRHVHSSERHFPCEMCAKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKTALRLHERTHTGDKPYGCTKCDAKFSQPSALKTHLRVHTGERPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCLRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQVNALQRHHRIHTGEKPYMCNACGRTFTDKSTLRRHTSIHDKNTPWKSFLVIVDGSPKNDEGHKTEQPDDEYASPKLSDRLLSFGENSHFNNLLEVQGNVPAVQENSSTGAACKAVVSQDALLTTSISALGELTPQAVSMPAHLPSLTNME", "length": 706 }, "evidence": [ { "id": "A0ABI0NYU0", "url": "https://omabrowser.org/oma/group/A0ABI0NYU0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H116-1", "protein_name": "GDNF-inducible zinc finger protein 1", "gene_name": "GZF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFFKEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLDLSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDSLDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKYTRRLREQQKTAEGDVGDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELSKKAGPEEEEEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANRCNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKTALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKNTPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDKLLSFAENGHFHNLAAVQDTVPTMQENSSADTACKADDSVVSQDTLLATTISELSELTPQTDSMPTQLHSLSNME", "length": 711 }, "evidence": [ { "id": "A0ABI0NYU0", "url": "https://omabrowser.org/oma/group/A0ABI0NYU0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYU0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYU0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYU0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYU0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYU0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYU0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYU0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYU0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYU0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYU0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NYU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 103, "start_aa": "Cys", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NYU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYU0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 322, "end_pos": 349, "start_aa": "Phe", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NWC8-1", "uniprot_ac": "A0ABI0NWC8", "uniprot_id": "A0ABI0NWC8_BOVIN", "mass": { "chemical_mass": 44092.0, "monoisotopic_mass": 44092.0 }, "refseq": {}, "gene_names": [ { "name": "UBE2Q1", "type": "recommended", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] } ], "protein_names": [ { "name": "E2 ubiquitin-conjugating enzyme", "type": "recommended", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.23", "type": "synonym", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWC8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UBE2Q1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8", "locus": { "chromosome": "3", "start_pos": 16032162, "end_pos": 16021541, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007515", "url": "https://www.ensembl.org/id/ENSBTAG00000007515" } ] } } ], "crossref": [ { "id": "ENSBTAG00000007515", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007515", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23802", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23802", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BIE5", "url": "https://www.orthodb.org/?gene=E1BIE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NWC8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWC8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIE5", "url": "https://www.uniprot.org/uniprotkb/E1BIE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIE5-1", "url": "https://www.uniprot.org/uniprotkb/E1BIE5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQQPQPQGQQQGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPPRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEDVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 396, "header": "tr|A0ABI0NWC8-1|A0ABI0NWC8_BOVIN Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Bos taurus OX=9913 GN=UBE2Q1 PE=4 SV=1 CANONICAL=A0ABI0NWC8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NWC8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8/entry#A0ABI0NWC8-1", "sequence": { "sequence": "MQQPQPQGQQQGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPPRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEDVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 396, "header": "tr|A0ABI0NWC8-1|A0ABI0NWC8_BOVIN Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Bos taurus OX=9913 GN=UBE2Q1 PE=4 SV=1 CANONICAL=A0ABI0NWC8-1" }, "locus": { "chromosome": "3", "start_pos": 16030380, "end_pos": 16022527, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154443.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154443.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104067.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104067.1" } ] } }, { "isoform_ac": "E1BIE5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8/entry#E1BIE5-1", "sequence": { "sequence": "MRKFRAESPACSPRLRTGEEGPRAGNTVPRSACLDELSCEFLLAGAGGAGAGAAPGPHLPPRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEDVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG", "length": 390, "header": "tr|E1BIE5-1|A0ABI0NWC8_BOVIN Computationally mapped isoform of E2 ubiquitin-conjugating enzyme OS=Bos taurus OX=9913 GN=UBE2Q1 PE=4 SV=2 CANONICAL=A0ABI0NWC8-1" }, "locus": { "chromosome": "3", "start_pos": 16030380, "end_pos": 16021760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009889.6", "url": "https://www.ensembl.org/id/ENSBTAT00000009889.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009889.5", "url": "https://www.ensembl.org/id/ENSBTAP00000009889.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWC8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWC8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWC8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWC8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWC8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983140" } ] }, { "id": "R-BTA-983152", "name": "Transfer of ubiquitin from E1 to E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A3KMV5-1", "A3KN22-1", "A6H795-1", "Q32PA5-1", "Q3MHP1-1", "A5PJC4-1", "Q0P5K3-1", "Q17QG5-1", "Q1RMW1-1", "Q1RMX2-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32P99-1", "Q1RML1-1", "A0A3Q1MLB6-1", "F1N1X8-1", "F1N3I3-1", "F1ME38-1", "A0A3Q1MAR8-1", "Q32L27-1", "A0ABI0NWC8-1" ], "evidence": [ { "id": "R-BTA-983152", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983152" } ] }, { "id": "R-BTA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983156" } ] }, { "id": "R-BTA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1MAR8", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] } ] }, { "uniprot_ac": "A0A3Q1MLB6", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MLB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLB6" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MLB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLB6" } ] } ] }, { "uniprot_ac": "A0A3Q1MLH2", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A3Q1MLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLH2" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A3Q1MLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLH2" } ] } ] }, { "uniprot_ac": "A0A3Q1N3G7", "gene_name": "TRIM36", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1N3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1N3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G7" } ] } ] }, { "uniprot_ac": "A0AAA9RXI4", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI4" } ] } ] }, { "uniprot_ac": "A0AAA9RXX2", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXX2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXX2" } ] } ] }, { "uniprot_ac": "A0AAA9RZ14", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ14" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0AAA9RZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ14" } ] } ] }, { "uniprot_ac": "A0AAA9S100", "gene_name": "MKRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9S100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S100" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9S100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S100" } ] } ] }, { "uniprot_ac": "A0AAA9TKS8", "gene_name": "RNF217", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0AAA9TKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKS8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0AAA9TKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKS8" } ] } ] }, { "uniprot_ac": "A0AAA9TWH7", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9TWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWH7" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0AAA9TWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWH7" } ] } ] }, { "uniprot_ac": "A0AAF6DMH9", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAF6DMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAF6DMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH9" } ] } ] }, { "uniprot_ac": "A0ABI0NWC8", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] } ] }, { "uniprot_ac": "A0JN74", "gene_name": "TRIM11", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0JN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JN74" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0JN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JN74" } ] } ] }, { "uniprot_ac": "A1A4I9", "gene_name": "UFL1", "activity": [ { "ec_number": "2.3.2.-", "activity": "", "evidence": [ { "id": "A1A4I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I9" } ] } ] }, { "uniprot_ac": "A3KMV5", "gene_name": "UBA1", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A3KMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KMV5" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A3KMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KMV5" } ] } ] }, { "uniprot_ac": "A3KN22", "gene_name": "UBE2M", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "A3KN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KN22" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "A3KN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KN22" } ] } ] }, { "uniprot_ac": "A5D7F8", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] } ] }, { "uniprot_ac": "A5PJC4", "gene_name": "UBE2L6", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] } ] }, { "uniprot_ac": "A5PKG6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5PKG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKG6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5PKG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKG6" } ] } ] }, { "uniprot_ac": "A6H795", "gene_name": "UBE2W", "activity": [ { "ec_number": "2.3.2.25", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-N-terminal-amino acid = [E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[acceptor protein].", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] } ] }, { "uniprot_ac": "E1B782", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B782" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1B782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B782" } ] } ] }, { "uniprot_ac": "E1B7D3", "gene_name": "TRIM39", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7D3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7D3" } ] } ] }, { "uniprot_ac": "E1B7G3", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] } ] }, { "uniprot_ac": "E1B7Q7", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7Q7" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1B7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7Q7" } ] } ] }, { "uniprot_ac": "E1B8R6", "gene_name": "ARIH2", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1B8R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R6" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1B8R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R6" } ] } ] }, { "uniprot_ac": "E1BAV2", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BAV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAV2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BAV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAV2" } ] } ] }, { "uniprot_ac": "E1BBN5", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] } ] }, { "uniprot_ac": "E1BBY2", "gene_name": "TRIM41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY2" } ] } ] }, { "uniprot_ac": "E1BCU1", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU1" } ] } ] }, { "uniprot_ac": "E1BCW1", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BCW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCW1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BCW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCW1" } ] } ] }, { "uniprot_ac": "E1BH71", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH71" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH71" } ] } ] }, { "uniprot_ac": "E1BID7", "gene_name": "TRIM69", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] } ] }, { "uniprot_ac": "E1BIP5", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1BIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1BIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ] } ] }, { "uniprot_ac": "E1BIW0", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BIW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BIW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW0" } ] } ] }, { "uniprot_ac": "E1BJS7", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS7" } ] } ] }, { "uniprot_ac": "E1BL26", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] } ] }, { "uniprot_ac": "E1BNQ6", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ] } ] }, { "uniprot_ac": "E1BNY9", "gene_name": "HUWE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] } ] }, { "uniprot_ac": "F1MBM6", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBM6" } ] } ] }, { "uniprot_ac": "F1ME38", "gene_name": "UBA6", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "F1ME38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME38" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "F1ME38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME38" } ] } ] }, { "uniprot_ac": "F1MEX6", "gene_name": "RNF19B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "F1MEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEX6" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "F1MEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEX6" } ] } ] }, { "uniprot_ac": "F1MJ10", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] } ] }, { "uniprot_ac": "F1MJS5", "gene_name": "HECTD3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJS5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJS5" } ] } ] }, { "uniprot_ac": "F1MLS5", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MLS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLS5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MLS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLS5" } ] } ] }, { "uniprot_ac": "F1MM41", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM41" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM41" } ] } ] }, { "uniprot_ac": "F1MTS8", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MTS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTS8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MTS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTS8" } ] } ] }, { "uniprot_ac": "F1MWS4", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MWS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWS4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MWS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWS4" } ] } ] }, { "uniprot_ac": "F1MYL0", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MYL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYL0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MYL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYL0" } ] } ] }, { "uniprot_ac": "F1N1X8", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1N1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1X8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1N1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1X8" } ] } ] }, { "uniprot_ac": "F1N3I3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3I3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "F1N3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3I3" } ] } ] }, { "uniprot_ac": "F1N495", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N495" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N495" } ] } ] }, { "uniprot_ac": "F1N5G3", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N5G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1N5G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5G3" } ] } ] }, { "uniprot_ac": "F1N645", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N645" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N645" } ] } ] }, { "uniprot_ac": "F1N6G5", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ] } ] }, { "uniprot_ac": "F1N703", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N703" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N703" } ] } ] }, { "uniprot_ac": "F1N7A0", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] } ] }, { "uniprot_ac": "P61085", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P61085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61085" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P61085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61085" } ] } ] }, { "uniprot_ac": "Q0II22", "gene_name": "RNF126", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q0II22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q0II22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II22" } ] } ] }, { "uniprot_ac": "Q0P5K3", "gene_name": "UBE2N", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] } ] }, { "uniprot_ac": "Q17QG5", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q17QG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QG5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q17QG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QG5" } ] } ] }, { "uniprot_ac": "Q1JQA1", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q1JQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q1JQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA1" } ] } ] }, { "uniprot_ac": "Q1RML1", "gene_name": "UBE2S", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q1RML1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RML1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q1RML1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RML1" } ] } ] }, { "uniprot_ac": "Q1RMW1", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q1RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMW1" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q1RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMW1" } ] } ] }, { "uniprot_ac": "Q1RMX2", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] } ] }, { "uniprot_ac": "Q29RQ5", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q29RQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RQ5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q29RQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RQ5" } ] } ] }, { "uniprot_ac": "Q2T9X7", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2T9X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2T9X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X7" } ] } ] }, { "uniprot_ac": "Q2TA03", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2TA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA03" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2TA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA03" } ] } ] }, { "uniprot_ac": "Q2TA10", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] } ] }, { "uniprot_ac": "Q32L27", "gene_name": "UBE2Q2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32L27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L27" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32L27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L27" } ] } ] }, { "uniprot_ac": "Q32LN1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] } ] }, { "uniprot_ac": "Q32LN5", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32LN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q32LN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN5" } ] } ] }, { "uniprot_ac": "Q32P99", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] } ] }, { "uniprot_ac": "Q32PA5", "gene_name": "UBE2C", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] } ] }, { "uniprot_ac": "Q3MHP1", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] } ] }, { "uniprot_ac": "Q4U5R4", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q4U5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4U5R4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q4U5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4U5R4" } ] } ] }, { "uniprot_ac": "Q5E9J6", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q5E9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q5E9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J6" } ] } ] }, { "uniprot_ac": "Q7YRV4", "gene_name": "TRIM21", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q7YRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRV4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q7YRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRV4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" }, { "id": "PS50127", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50127" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBC core", "eco_id": "ECO_0000259", "start_pos": 225, "end_pos": 389, "start_aa": "Gln", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.23", "ec_name": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "2.3.2.23", "database": "BRENDA Enzymes", "url": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NV07-1", "uniprot_ac": "A0ABI0NV07", "uniprot_id": "A0ABI0NV07_BOVIN", "mass": { "chemical_mass": 71659.0, "monoisotopic_mass": 71659.0 }, "refseq": {}, "gene_names": [ { "name": "LOC524642", "type": "recommended", "evidence": [ { "id": "A0ABI0NV07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV07" } ] } ], "protein_names": [ { "name": "GP-PDE domain-containing protein", "type": "recommended", 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23344", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23344:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23344:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NKA4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKA4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NV07", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NV07-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P243", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P243", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P243-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P243-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDINRTETGNEETGRWKNFNSWIKYYFNYECYMTFLNGCYSCKWEAQQKKKAKRPLCCCSLRERLFYPWLIMSFCLSVLLFFTWIETSNEFNGFDWVVFLGTGVWFFWSIVLLSFLGILAAYTTLLLVLGFLLCWEKQRLYLHWYHKILVLIMIPFFSLLLWILLTYWKDRWLTIGLSLQILAPYVHLSSISVMVLLSWPVAFYLIHLEGEARMRRYQITSNERRRNTCCSMLTKLRALQVAVGVPFFFILLCLYVVPFGTYSPCLQEKEKLAPKPNFFGHRGAPMLGPENTIMSFEKAVEYGAHGLESDVQISFDGVPFLMHDYDLRRTTNIKEVLPDAARRHPSLFRWSFLTTLNAGKWFSDVKPFFRMKPLSEDDKERARNQRIAKLTDLLAIAQKEKKLVIFDLNAPPSRHPSRLSYIHLVVRVILDSKIEQHLIAWLPGSERRYIKSKAPGFQHVGTFYTLQELADENITRINVDYKRLYYNGLREYKAANISINLYIVNEPWLFSLVWCHSIHSVTTDNIEVLNEMNHPYYFMSLSPTLPLHCPLCSPQGSYLRAETICDIGDKALFLLSPRSFCYSQGEITVGINNWLFIESPQCAFLGFCNSTL", "length": 613, "header": "tr|A0ABI0NV07-1|A0ABI0NV07_BOVIN Isoform 1 of GP-PDE domain-containing protein OS=Bos taurus OX=9913 GN=LOC524642 PE=3 SV=1 CANONICAL=A0ABI0NV07-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NKA4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV07/entry#A0ABI0NKA4-1", "sequence": { "sequence": "SFISLKILNIFFIGNYSQIAPLLIPLFSYASSSPVLSPILGRDTTNFFILEIETHFCRVVFLGTGVWFFWSIVLLSFLGILAAYTTLLLVLGFLLCWEKQRLYLHWYHKILVLIMIPFFSLLLWILLTYWKDRWLTIGLSLQILAPYVHLSSISVMVLLSWPVAFYLIHLEGEARMRRYQITSNERRRNTCCSMLTKLRALQVAVGVPFFFILLCLYVVPFGTYSPCLQEKEKLAPKPNFFGHRGAPMLGPENTIMSFEKAVEYGAHGLESDVQISFDGVPFLMHDYDLRRTTNIKEVLPDAARRHPSLFRWSFLTTLNAGKWFSDAWVKPFFRMKPLSEDDKERARNQRIAKLTDLLAIAQKEKKLVIFDLNAPPSRHPSRLSYIHLVVRVILDSKIEQHLIAWLPGSERRYIKSKAPGFQHVGTFYTLQELADENITRINVDYKRLYYNGLREYKAANISINLYIVNEPWLFSLVWCHSIHSVTTDNIEVLNEMNHPYYFMTPNFYLFLWIFMDILSAVFIVSIFRFHWWRESQSEKIRQGITSYTGKVRGLAPSNLFIPPHCLHEAGLALNISDKN", "length": 579, "header": "tr|A0ABI0NKA4-1|A0ABI0NV07_BOVIN Computationally mapped isoform of GP-PDE domain-containing protein OS=Bos taurus OX=9913 GN=LOC524642 PE=3 SV=1 CANONICAL=A0ABI0NV07-1" }, "locus": { "chromosome": "29", "start_pos": 19083262, "end_pos": 18992423, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153711.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153711.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105096.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105096.1" } ] } }, { "isoform_ac": "A0ABI0NV07-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV07/entry#A0ABI0NV07-1", "sequence": { "sequence": "MDDINRTETGNEETGRWKNFNSWIKYYFNYECYMTFLNGCYSCKWEAQQKKKAKRPLCCCSLRERLFYPWLIMSFCLSVLLFFTWIETSNEFNGFDWVVFLGTGVWFFWSIVLLSFLGILAAYTTLLLVLGFLLCWEKQRLYLHWYHKILVLIMIPFFSLLLWILLTYWKDRWLTIGLSLQILAPYVHLSSISVMVLLSWPVAFYLIHLEGEARMRRYQITSNERRRNTCCSMLTKLRALQVAVGVPFFFILLCLYVVPFGTYSPCLQEKEKLAPKPNFFGHRGAPMLGPENTIMSFEKAVEYGAHGLESDVQISFDGVPFLMHDYDLRRTTNIKEVLPDAARRHPSLFRWSFLTTLNAGKWFSDVKPFFRMKPLSEDDKERARNQRIAKLTDLLAIAQKEKKLVIFDLNAPPSRHPSRLSYIHLVVRVILDSKIEQHLIAWLPGSERRYIKSKAPGFQHVGTFYTLQELADENITRINVDYKRLYYNGLREYKAANISINLYIVNEPWLFSLVWCHSIHSVTTDNIEVLNEMNHPYYFMSLSPTLPLHCPLCSPQGSYLRAETICDIGDKALFLLSPRSFCYSQGEITVGINNWLFIESPQCAFLGFCNSTL", "length": 613, "header": "tr|A0ABI0NV07-1|A0ABI0NV07_BOVIN Isoform 1 of GP-PDE domain-containing protein OS=Bos taurus OX=9913 GN=LOC524642 PE=3 SV=1 CANONICAL=A0ABI0NV07-1" }, "locus": { "chromosome": "29", "start_pos": 19073989, "end_pos": 18983511, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154731.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154731.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104443.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104443.1" } ] } }, { "isoform_ac": "A0ABI0P243-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV07/entry#A0ABI0P243-1", "sequence": { "sequence": "SFLGILAAYTTLLLVLGFLLCWEKQRLYLHWYHKILVLIMIPFFSLLLWILLTYWKDRWLTIGLSLQILAPYVHLSSISVMVLLSWPVAFYLIHLEGEARMRRYQITSNERRRNTCCSMLTKLRALQVAVGVPFFFILLCLYVVPFGTYSPCLQEKEKLAPKPNFFGHRGAPMLGPENTIMSFEKAVEYGAHGLESDVQISFDGVPFLMHDYDLRRTTNIKEVLPDAARRHPSLFRWSFLTTLNAGKWFSDVKPFFRMKPLSEDDKERARNQRIAKLTDLLAIAQKEKKLVIFDLNAPPSRHPSRLSYIHLVVRVILDSKIEQHLIAWLPGSERRYIKSKAPGFQHVGTFYTLQELADENITRINVDYKRLYYNGLREYKAANISINLYIVNEPWLFSLVWCHSIHSVTTDNIEVLNEMNHPYYFMTPNFYLFLWIFMDILSAVFIVSIFRFHWNLCCFLFYPTEASSASLQNEVVEIMGIPAPFPEREREPPSSKAVVPEIVNETTISTVHPTDDIGQPVPTEPAFEPIQAPTSEANREATLQTVLPTLEANEPTVPSVEKPPPET", "length": 567, "header": "tr|A0ABI0P243-1|A0ABI0P243_BOVIN Computationally mapped isoform of GP-PDE domain-containing protein OS=Bos taurus OX=9913 GN=LOC524642 PE=3 SV=1 CANONICAL=A0ABI0NV07-1" }, "locus": { "chromosome": "29", "start_pos": 19094300, "end_pos": 18993406, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150680.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150680.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105122.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105122.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV07", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV07" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV07", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV07" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NV07", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV07" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NV07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV07" }, { "id": "PS51704", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51704" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GP-PDE", "eco_id": "ECO_0000259", "start_pos": 277, "end_pos": 534, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 474, "end_pos": 476 }, { "start_pos": 497, "end_pos": 499 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 610, "end_pos": 612 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", 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"categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015925", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015925", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46399:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46399:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01365", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01365", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06459", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06459", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08709", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08709", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21119", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21119", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NLW8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLW8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM46", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM46-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZM1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZM1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGGEGGEDEIQFLRTEDEVVLQCIANVHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVPPDLCVCNFVLEQSLSVRALQEMLANTGENGGEGAAQGGGHRTLLYGHAILLRHSFSGMYLTCLTTSRSQTDKLAFDVGLREHATGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSISNGNIQVDASFMQTLWNVHPTCSGSSIEEGYLLGGHVVRLFHGHDECLTIPSTDQNDSQHRRIYYEAGGAGTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGHYLALTEDQGLILQDRGKSDTKSTAFSFRASKEIKEKLDSSHKRDIEGMGVPEIKYGDSVCFVQHIASGLWVTYKAQDAKTSRLGPLKRKVILHQEGHMDDGLTLQRCQREESQAARIIRNTTALFSQFVSGNSRTAAPVTLPIEEVLQTLHDLIAYFQPPEEGMQHEGKQNKLRSLKNRQNLFKEEGMLALVLNCIDRLNIYNSIAHFAGIAREESGMAWKEILNLLYKLLAALIRGNRNNCAQFSNNLDWLISKLDRLESSSGILEVLHCILIESPEALNLIAEGHIKSIISLLDKHGRNHKVLDVLCSLCLCDGVAVRANQNLICDNLLPRRNLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKWYFELIIDQVDPFLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGRIPRAVASINQHLLKSDDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPSGYAPCYEALLPKEKMRLEPVKEYKRDAEGIRDLLGTTQFLSQASFIPCPIDTSQVVLPPHLEKIRDRLAENIHELWGMNKIELGWTFGKIRDDNKRQHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIAHVNPAAEDDLKKVKLPKNYMMSNGYKPAPLDLSDVKLLPPQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVPYSLLDERTKKSNRDSLREAVRTFVGYGYNIEPSDQELADPAVEKVSIDKIRFFRVERSYAVRSGKWYFEFEVVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSRGQRWHQGSGYFGRTWQPGDVVGCMINLDDASMIFTLNGELLITNKGSELAFADYEIDNGFVPICSLGLSQIGRMNLGMDASTFKFYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPQIEVVRIDGTMDTPPCLKVTHKTFGTQNSSATMIYCRLSMPVECHSSFSHSPCMDSDAFQKRKQMQEILSHTTTQCYYAIRIFAGQDPSCVWVGWVTPDYHLYSEKFDLNKNCTVTVTLGDERGRVHESVKRSNCYMVWGGDIVATSQRASRSNVDLEIGCLVDLAMGMLSFSANGRELGTCYQVEPNTKVFPAVFLQPTSTSLFQFELGKLKNAMPLSAAIFKSEEKNPVPQCPPRLDVQTIQPVLWSRMPSSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMRFHYHTLRLYSALCALGNSRVAYALCSHVDLSQLFYAIDNKYLPGLLRSGFYDLLISIHLASAKERKLMMKNEYIIPITSTTRKIRLYPDESKRHGLPGVGPRTCLKPGFRFSTPCFITTNEEHQKQSPEIPLELLKTKALGMLTEAVQCSGAHIRDPVGGSVEFQFVPVLKLIGTLLIMGVFDDDDVRQILLLIDPSVFGEHSGETEEGAEKEEVTQVEEKAVEAGEKASREAPIKGLLQTRLPESVKLQMCELLSYLCDCELQHRVEAIVAFGDIYVSKLQENQKFRYNELMQALNMSAALTARKTREFRSPPQEQINMLLNFQLGENCPCPEEIREELYDFHEDLLLHCGVPLEEEEEEEEDSSWTGKFCALVQRIKGPPKPEKEQPTEEEERCPTTLKELISQTMIRWAQEDQIQDAELVRMMFNLLRRQYDSIGELLQALRKTYTISQASVSDTISLLAALGQIRCLLSVRMGKEEELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGAEKLQIAFPKMVASCCRFLCYFCRISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELALGLEEPDLEKVVTYLAGCGLQSCPMLLAKGYPDVGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKLLIRRPECFGPALRGEGGNGLLAAMQGAIKISENPALDLPSQGYKREVSTEDDDDEEEIVHMGNAIMSFYSALIDLLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLPSLNKDGSVSEPDMAANFCPDHKAPMVLFLDRVYGIKDQTFLLHLLEVGFLPDLRASASLDTVSLSTTEAALALNRYICSAVLPLLTRCAPLFAGTEHYTSLIDSTLQTIYRLSKGRSLTKAQRDTIEECLLAICNHLRPSMLQQLLRRLVFDVPQLNEYCKMPLKLLTNHYEQCWKYYCLPSGWGSYGLAVEEELHLTEKLFWGIFDSLSHKRYDPDLFRMALPCLSAIAGALPPDYLDTRISATLEKQVSVDTDGNFDPKPINTVNFSLPEKLEYIVTKYAEHSHDRWACDKSQNGWKYGISLDENVKTHPLIRPFKTLTEKEKDIYRWPARESLKTMLAVGWTVERTKEGEALVQQRENEKLRSVSQASQGNSYSPAPLDLSNVVLSRELQGMVEVVAENYHNIWAKKKKLELESKGGGSHPLLVPYDTLTAKEKFRDREKAQDLFKFLQVNGIVVSRGMKDMELDASSMEKRFAYKFLKKVLKYVDSAQEFIAHLEAIVSSGKNEKSPHDQEIKFFAKVLLPLVDQYFINHRLYFLSSPLKPLSSSGYASHKEKEMVASLFCKLAALVRHRISLFGSDSTTMVSCLHILAQTLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTLENLKLGKFTHSRTQIKGVSQNINYTTVALLPILTSIFEHVAQHQFGVDLLLGDVQLSCYHILCSLYSLGTGKNIYVERQRPALGECLASLAAAIPVAFLEPTLNRYNPLSVFNTKTPRERSILGMPDTVEEMCPDIPQLEGLMKEINDLAESGARYTEMPHVIEVILPMLCNYLSYWWERGPEHLPPSAGPWCTKVTSEHLSVILGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLRSHFIPTLEKLKKKAIKTVQEEEQLRADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSNWLKSPDADSDQLFRMVAEIFILWCKSHNFKREEQNFVIQNEINNLAFLTGDSKSKMSKAMQVKSGGQDQERKKTKRRGDFYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKSRYSYKDTDEEVKEHLRNNLHLQEKSDDPAVKWQLNLYKDVLKSEEPSNPEKTVERVQRISAAVFHLEQVEQPLRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQRFWIETEEYSFEEKLVQDLAKSPKVEEEEEEEVEKQPDPLHQIILHFSRNALTERSKLEDDPLYTSYASMMAKSCQSGEDEDEDEDKEKTFEEKEMEKQKTLYQQARLHERGAAEMVLQMISASKGEMSPMVVETLKLGIAILNGGNAGVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKVLQNDEFTRDLFRFLQLLCEGHNSDFQNFLRTQMGNTTTVNVIISTVDYLLRLQESISDFYWYYSGKDIIDESGQHNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSTNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGIISKKEFQKAMEGQKQYTQSEIDFLLSCAEADENDMFNYIDFVDRFHEPAKDIGFNVAVLLTNLSEHMPNDSRLKCLLDPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISESDSADRPDEEEEEGGDSSYVLEVEGEEEEEEKSFECASAFAMACGSVKRNVANFLKRATLKNLRKQYRKVKKMTFKELVKVFFSFFWTLFMGLFHLLFTIVGGIIQVLWSTVFGGGLIEGAKNIRVTKILGDMPDPTQFGIHDDAMEAERAEVPEPGIATELVHFVKGQKGDADIMSDLFGLHPKKEGGLKHGPEVGLGDLSEIIGKDETPTLESTVRKKRKAQAAEMKAAHEAERKIESEKADMEDGEKEDTAKEEEQAEALWADVTKRKKRRCGQKVEKPEAFMANFFKGLEIYQTKLLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLEEETEDVANLWNSFNDEEEEEAVVFFVLQESTGYMAPTLRALAIIHTVISLVCVVGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKNALDFSPVEETKAEAASLVSWLSSIDMKYHVWKLGVVFTDNSFLYLAWYTTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDDDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG", "length": 4872, "header": "tr|A0ABI0NZM1-1|A0ABI0NZM1_BOVIN Isoform 1 of Ryanodine receptor 3 OS=Bos taurus OX=9913 GN=RYR3 PE=3 SV=1 CANONICAL=A0ABI0NZM1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NLW8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZM1/entry#A0ABI0NLW8-1", "sequence": { "sequence": "MAEGGEGGEDEIQFLRTEDEVVLQCIANVHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVPPDLCVCNFVLEQSLSVRALQEMLANTGENGGEGAAQGGGHRTLLYGHAILLRHSFSGMYLTCLTTSRSQTDKLAFDVGLREHATGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSISNGNIQVDASFMQTLWNVHPTCSGSSIEEGYLLGGHVVRLFHGHDECLTIPSTDQNDSQHRRIYYEAGGAGTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGHYLALTEDQGLILQDRGKSDTKSTAFSFRASKEIKEKLDSSHKRDIEGMGVPEIKYGDSVCFVQHIASGLWVTYKAQDAKTSRLGPLKRKVILHQEGHMDDGLTLQRCQREESQAARIIRNTTALFSQFVSGNSRTAAPVTLPIEEVLQTLHDLIAYFQPPEEGMQHEGKQNKLRSLKNRQNLFKEEGMLALVLNCIDRLNIYNSIAHFAGIAREESGMAWKEILNLLYKLLAALIRGNRNNCAQFSNNLDWLISKLDRLESSSGILEVLHCILIESPEALNLIAEGHIKSIISLLDKHGRNHKVLDVLCSLCLCDGVAVRANQNLICDNLLPRRNLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKWYFELIIDQVDPFLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGRIPRAVASINQHLLKSDDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPSGYAPCYEALLPKEKMRLEPVKEYKRDAEGIRDLLGTTQFLSQASFIPCPIDTSQVVLPPHLEKIRDRLAENIHELWGMNKIELGWTFGKIRDDNKRQHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIAHVNPAAEDDLKKVKLPKNYMMSNGYKPAPLDLSDVKLLPPQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVPYSLLDERTKKSNRDSLREAVRTFVGYGYNIEPSDQELADPAVEKVSIDKIRFFRVERSYAVRSGKWYFEFEVVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSRGQRWHQGSGYFGRTWQPGDVVGCMINLDDASMIFTLNGELLITNKGSELAFADYEIDNGFVPICSLGLSQIGRMNLGMDASTFKFYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPQIEVVRIDGTMDTPPCLKVTHKTFGTQNSSATMIYCRLSMPVECHSSFSHSPCMDSDAFQKRKQMQEILSHTTTQCYYAIRIFAGQDPSCVWVGWVTPDYHLYSEKFDLNKNCTVTVTLGDERGRVHESVKRSNCYMVWGGDIVATSQRASRSNVDLEIGCLVDLAMGMLSFSANGRELGTCYQVEPNTKVFPAVFLQPTSTSLFQFELGKLKNAMPLSAAIFKSEEKNPVPQCPPRLDVQTIQPVLWSRMPSSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMRFHYHTLRLYSALCALGNSRVAYALCSHVDLSQLFYAIDNKYLPGLLRSGFYDLLISIHLASAKERKLMMKNEYIIPITSTTRKIRLYPDESKRHGLPGVGPRTCLKPGFRFSTPCFITTNEEHQKQSPEIPLELLKTKALGMLTEAVQCSGAHIRDPVGGSVEFQFVPVLKLIGTLLIMGVFDDDDVRQILLLIDPSVFGEHSGETEEGAEKEEVTQVEEKAVEAGEKASREAPIKGLLQTRLPESVKLQMCELLSYLCDCELQHRVEAIVAFGDIYVSKLQENQKFRYNELMQALNMSAALTARKTREFRSPPQEQINMLLNFQLGENCPCPEEIREELYDFHEDLLLHCGVPLEEEEEEEEDSSWTGKFCALVQRIKGPPKPEKEQPTEEEERCPTTLKELISQTMIRWAQEDQIQDAELVRMMFNLLRRQYDSIGELLQALRKTYTISQASVSDTISLLAALGQIRCLLSVRMGKEEELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGAEKLQIAFPKMVASCCRFLCYFCRISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELALGLEEPDLEKVVTYLAGCGLQSCPMLLAKGYPDVGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKLLIRRPECFGPALRGEGGNGLLAAMQGAIKISENPALDLPSQGYKREVSTEDDDDEEEIVHMGNAIMSFYSALIDLLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLPSLNKDGSVSEPDMAANFCPDHKAPMVLFLDRVYGIKDQTFLLHLLEVGFLPDLRASASLDTVSLSTTEAALALNRYICSAVLPLLTRCAPLFAGTEHYTSLIDSTLQTIYRLSKGRSLTKAQRDTIEECLLAICNHLRPSMLQQLLRRLVFDVPQLNEYCKMPLKLLTNHYEQCWKYYCLPSGWGSYGLAVEEELHLTEKLFWGIFDSLSHKRYDPDLFRMALPCLSAIAGALPPDYLDTRISATLEKQVSVDTDGNFDPKPINTVNFSLPEKLEYIVTKYAEHSHDRWACDKSQNGWKYGISLDENVKTHPLIRPFKTLTEKEKDIYRWPARESLKTMLAVGWTVERTKEGEALVQQRENEKLRSVSQASQGNSYSPAPLDLSNVVLSRELQGMVEVVAENYHNIWAKKKKLELESKGGGSHPLLVPYDTLTAKEKFRDREKAQDLFKFLQVNGIVVSRGMKDMELDASSMEKRFAYKFLKKVLKYVDSAQEFIAHLEAIVSSGKNEKSPHDQEIKFFAKVLLPLVDQYFINHRLYFLSSPLKPLSSSGYASHKEKEMVASLFCKLAALVRHRISLFGSDSTTMVSCLHILAQTLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTLENLKLGKFTHSRTQIKGVSQNINYTTVALLPILTSIFEHVAQHQFGVDLLLGDVQLSCYHILCSLYSLGTGKNIYVERQRPALGECLASLAAAIPVAFLEPTLNRYNPLSVFNTKTPRERSILGMPDTVEEMCPDIPQLEGLMKEINDLAESGARYTEMPHVIEVILPMLCNYLSYWWERGPEHLPPSAGPWCTKVTSEHLSVILGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLRSHFIPTLEKLKKKAIKTVQEEEQLRADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSNWLKSPDADSDQLFRMVAEIFILWCKSHNFKREEQNFVIQNEINNLAFLTGDSKSKMSKSGGQDQERKKTKRRGDFYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKSRYSYKDTDEEVKEHLRNNLHLQEKSDDPAVKWQLNLYKDVLKSEEPSNPEKTVERVQRISAAVFHLEQVEQPLRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQRFWIETEEYSFEEKLVQDLAKSPKVEEEEEEEVEKQPDPLHQIILHFSRNALTERSKLEDDPLYTSYASMMAKSCQSGEDEDEDEDKEKTFEEKEMEKQKTLYQQARLHERGAAEMVLQMISASKGEMSPMVVETLKLGIAILNGGNAGVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKVLQNDEFTRDLFRFLQLLCEGHNSDFQNFLRTQMGNTTTVNVIISTVDYLLRLQESISDFYWYYSGKDIIDESGQHNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSTNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGIISKKEFQKAMEGQKQYTQSEIDFLLSCAEADENDMFNYIDFVDRFHEPAKDIGFNVAVLLTNLSEHMPNDSRLKCLLDPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISESDSADRPDEEEEEGGDSSYVLEVEGEEEEEEKSFECASAFAMACGSVKRNVANFLKRATLKNLRKQYRKVKKMTFKELVKVFFSFFWTLFMGLFHLLFTIVGGIIQVLWSTVFGGGLIEGAKNIRVTKILGDMPDPTQFGIHDDAMEAERAEVPEPGIATELVHFVKGQKGDADIMSDLFGLHPKKEGGLKHGPEVGLGDLSEIIGKDETPTLESTVRKKRKAQAAEMKAAHEAERKIESEKADMEDGEKEDTAKEEEQAEALWADVTKRKKRRCGQKVEKPEAFMANFFKGLEIYQTKLLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLEEETEDVANLWNSFNDEEEEEAVVFFVLQESTGYMAPTLRALAIIHTVISLVCVVGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKNALDFSPVEETKAEAASLVSWLSSIDMKYHVWKLGVVFTDNSFLYLAWYTTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDDDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG", "length": 4867, "header": "tr|A0ABI0NLW8-1|A0ABI0NZM1_BOVIN Computationally mapped isoform of Ryanodine receptor 3 OS=Bos taurus OX=9913 GN=RYR3 PE=3 SV=1 CANONICAL=A0ABI0NZM1-1" }, "locus": { "chromosome": "10", "start_pos": 29286406, "end_pos": 28728710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150531.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150531.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106316.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106316.1" } ] } }, { "isoform_ac": "A0ABI0NM46-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZM1/entry#A0ABI0NM46-1", "sequence": { "sequence": "MAEGGEGGEDEIQFLRTEDEVVLQCIANVHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVPPDLCVCNFVLEQSLSVRALQEMLANTGENGGEGAAQGGGHRTLLYGHAILLRHSFSGMYLTCLTTSRSQTDKLAFDVGLREHATGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSISNGNIQVDASFMQTLWNVHPTCSGSSIEEGYLLGGHVVRLFHGHDECLTIPSTDQNDSQHRRIYYEAGGAGTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGHYLALTEDQGLILQDRGKSDTKSTAFSFRASKEIKEKLDSSHKRDIEGMGVPEIKYGDSVCFVQHIASGLWVTYKAQDAKTSRLGPLKRKVILHQEGHMDDGLTLQRCQREESQAARIIRNTTALFSQFVSGNSRTAAPVTLPIEEVLQTLHDLIAYFQPPEEGMQHEGKQNKLRSLKNRQNLFKEEGMLALVLNCIDRLNIYNSIAHFAGIAREESGMAWKEILNLLYKLLAALIRGNRNNCAQFSNNLDWLISKLDRLESSSGILEVLHCILIESPEALNLIAEGHIKSIISLLDKHGRNHKVLDVLCSLCLCDGVAVRANQNLICDNLLPRRNLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKWYFELIIDQVDPFLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGRIPRAVASINQHLLKSDDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPSGYAPCYEALLPKEKMRLEPVKEYKRDAEGIRDLLGTTQFLSQASFIPCPIDTSQVVLPPHLEKIRDRLAENIHELWGMNKIELGWTFGKIRDDNKRQHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIAHVNPAAEDDLKKVKLPKNYMMSNGYKPAPLDLSDVKLLPPQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVPYSLLDERTKKSNRDSLREAVRTFVGYGYNIEPSDQELADPAVEKVSIDKIRFFRVERSYAVRSGKWYFEFEVVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSRGQRWHQGSGYFGRTWQPGDVVGCMINLDDASMIFTLNGELLITNKGSELAFADYEIDNGFVPICSLGLSQIGRMNLGMDASTFKFYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPQIEVVRIDGTMDTPPCLKVTHKTFGTQNSSATMIYCRLSMPVECHSSFSHSPCMDSDAFQKRKQMQEILSHTTTQCYYAIRIFAGQDPSCVWVGWVTPDYHLYSEKFDLNKNCTVTVTLGDERGRVHESVKRSNCYMVWGGDIVATSQRASRSNVDLEIGCLVDLAMGMLSFSANGRELGTCYQVEPNTKVFPAVFLQPTSTSLFQFELGKLKNAMPLSAAIFKSEEKNPVPQCPPRLDVQTIQPVLWSRMPSSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMRFHYHTLRLYSALCALGNSRVAYALCSHVDLSQLFYAIDNKYLPGLLRSGFYDLLISIHLASAKERKLMMKNEYIIPITSTTRKIRLYPDESKRHGLPGVGPRTCLKPGFRFSTPCFITTNEEHQKQSPEIPLELLKTKALGMLTEAVQCSGAHIRDPVGGSVEFQFVPVLKLIGTLLIMGVFDDDDVRQILLLIDPSVFGEHSGETEEGAEKEEVTQVEEKAVEAGEKASREAPIKGLLQTRLPESVKLQMCELLSYLCDCELQHRVEAIVAFGDIYVSKLQENQKFRYNELMQALNMSAALTARKTREFRSPPQEQINMLLNFQLGENCPCPEEIREELYDFHEDLLLHCGVPLEEEEEEEEDSSWTGKFCALVQRIKGPPKPEKEQPTEEEERCPTTLKELISQTMIRWAQEDQIQDAELVRMMFNLLRRQYDSIGELLQALRKTYTISQASVSDTISLLAALGQIRCLLSVRMGKEEELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGAEKLQIAFPKMVASCCRFLCYFCRISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELALGLEEPDLEKVVTYLAGCGLQSCPMLLAKGYPDVGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKLLIRRPECFGPALRGEGGNGLLAAMQGAIKISENPALDLPSQGYKREVTEDDDDEEEIVHMGNAIMSFYSALIDLLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLPSLNKDGSVSEPDMAANFCPDHKAPMVLFLDRVYGIKDQTFLLHLLEVGFLPDLRASASLDTVSLSTTEAALALNRYICSAVLPLLTRCAPLFAGTEHYTSLIDSTLQTIYRLSKGRSLTKAQRDTIEECLLAICNHLRPSMLQQLLRRLVFDVPQLNEYCKMPLKLLTNHYEQCWKYYCLPSGWGSYGLAVEEELHLTEKLFWGIFDSLSHKRYDPDLFRMALPCLSAIAGALPPDYLDTRISATLEKQVSVDTDGNFDPKPINTVNFSLPEKLEYIVTKYAEHSHDRWACDKSQNGWKYGISLDENVKTHPLIRPFKTLTEKEKDIYRWPARESLKTMLAVGWTVERTKEGEALVQQRENEKLRSVSQASQGNSYSPAPLDLSNVVLSRELQGMVEVVAENYHNIWAKKKKLELESKGGGSHPLLVPYDTLTAKEKFRDREKAQDLFKFLQVNGIVVSRGMKDMELDASSMEKRFAYKFLKKVLKYVDSAQEFIAHLEAIVSSGKNEKSPHDQEIKFFAKVLLPLVDQYFINHRLYFLSSPLKPLSSSGYASHKEKEMVASLFCKLAALVRHRISLFGSDSTTMVSCLHILAQTLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTLENLKLGKFTHSRTQIKGVSQNINYTTVALLPILTSIFEHVAQHQFGVDLLLGDVQLSCYHILCSLYSLGTGKNIYVERQRPALGECLASLAAAIPVAFLEPTLNRYNPLSVFNTKTPRERSILGMPDTVEEMCPDIPQLEGLMKEINDLAESGARYTEMPHVIEVILPMLCNYLSYWWERGPEHLPPSAGPWCTKVTSEHLSVILGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLRSHFIPTLEKLKKKAIKTVQEEEQLRADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSNWLKSPDADSDQLFRMVAEIFILWCKSHNFKREEQNFVIQNEINNLAFLTGDSKSKMSKSGGQDQERKKTKRRGDFYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKSRYSYKDTDEEVKEHLRNNLHLQEKSDDPAVKWQLNLYKDVLKSEEPSNPEKTVERVQRISAAVFHLEQVEQPLRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHKINNFFLSTFQRVWLEKVNEKTQYDRLILILMKSPKVEEEEEEEVEKQPDPLHQIILHFSRNALTERSKLEDDPLYTSYASMMAKSCQSGEDEDEDEDKEKTFEEKEMEKQKTLYQQARLHERGAAEMVLQMISASKGEMSPMVVETLKLGIAILNGGNAGVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTREKVLQNDEFTRDLFRFLQLLCEGHNSDFQNFLRTQMGNTTTVNVIISTVDYLLRLQESISDFYWYYSGKDIIDESGQHNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSTNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGIISKKEFQKAMEGQKQYTQSEIDFLLSCAEADENDMFNYIDFVDRFHEPAKDIGFNVAVLLTNLSEHMPNDSRLKCLLDPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISESDSADRPDEEEEEGGDSSYVLEVEGEEEEEEKSFECASAFAMACGSVKRNVANFLKRATLKNLRKQYRKVKKMTFKELVKVFFSFFWTLFMGLFHLLFTIVGGIIQVLWSTVFGGGLIEGAKNIRVTKILGDMPDPTQFGIHDDAMEAERAEVPEPGIATELVHFVKGQKGDADIMSDLFGLHPKKEGGLKHGPEVGLGDLSEIIGKDETPTLESTVRKKRKAQAAEMKAAHEAERKIESEKADMEDGEKEDTAKEEEQAEALWADVTKRKKRRCGQKVEKPEAFMANFFKGLEIYQTKLLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLEEETEDVANLWNSFNDEEEEEAVVFFVLQESTGYMAPTLRALAIIHTVISLVCVVGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKNALDFSPVEETKAEAASLVSWLSSIDMKYHVWKLGVVFTDNSFLYLAWYTTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDDDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG", "length": 4861, "header": "tr|A0ABI0NM46-1|A0ABI0NZM1_BOVIN Computationally mapped isoform of Ryanodine receptor 3 OS=Bos taurus OX=9913 GN=RYR3 PE=3 SV=1 CANONICAL=A0ABI0NZM1-1" }, "locus": { "chromosome": "10", "start_pos": 29286406, "end_pos": 28728710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144155.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144155.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106373.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106373.1" } ] } }, { "isoform_ac": "A0ABI0NZM1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZM1/entry#A0ABI0NZM1-1", "sequence": { "sequence": "MAEGGEGGEDEIQFLRTEDEVVLQCIANVHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVPPDLCVCNFVLEQSLSVRALQEMLANTGENGGEGAAQGGGHRTLLYGHAILLRHSFSGMYLTCLTTSRSQTDKLAFDVGLREHATGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSISNGNIQVDASFMQTLWNVHPTCSGSSIEEGYLLGGHVVRLFHGHDECLTIPSTDQNDSQHRRIYYEAGGAGTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGHYLALTEDQGLILQDRGKSDTKSTAFSFRASKEIKEKLDSSHKRDIEGMGVPEIKYGDSVCFVQHIASGLWVTYKAQDAKTSRLGPLKRKVILHQEGHMDDGLTLQRCQREESQAARIIRNTTALFSQFVSGNSRTAAPVTLPIEEVLQTLHDLIAYFQPPEEGMQHEGKQNKLRSLKNRQNLFKEEGMLALVLNCIDRLNIYNSIAHFAGIAREESGMAWKEILNLLYKLLAALIRGNRNNCAQFSNNLDWLISKLDRLESSSGILEVLHCILIESPEALNLIAEGHIKSIISLLDKHGRNHKVLDVLCSLCLCDGVAVRANQNLICDNLLPRRNLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKWYFELIIDQVDPFLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGRIPRAVASINQHLLKSDDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPSGYAPCYEALLPKEKMRLEPVKEYKRDAEGIRDLLGTTQFLSQASFIPCPIDTSQVVLPPHLEKIRDRLAENIHELWGMNKIELGWTFGKIRDDNKRQHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIAHVNPAAEDDLKKVKLPKNYMMSNGYKPAPLDLSDVKLLPPQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVPYSLLDERTKKSNRDSLREAVRTFVGYGYNIEPSDQELADPAVEKVSIDKIRFFRVERSYAVRSGKWYFEFEVVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSRGQRWHQGSGYFGRTWQPGDVVGCMINLDDASMIFTLNGELLITNKGSELAFADYEIDNGFVPICSLGLSQIGRMNLGMDASTFKFYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPQIEVVRIDGTMDTPPCLKVTHKTFGTQNSSATMIYCRLSMPVECHSSFSHSPCMDSDAFQKRKQMQEILSHTTTQCYYAIRIFAGQDPSCVWVGWVTPDYHLYSEKFDLNKNCTVTVTLGDERGRVHESVKRSNCYMVWGGDIVATSQRASRSNVDLEIGCLVDLAMGMLSFSANGRELGTCYQVEPNTKVFPAVFLQPTSTSLFQFELGKLKNAMPLSAAIFKSEEKNPVPQCPPRLDVQTIQPVLWSRMPSSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMRFHYHTLRLYSALCALGNSRVAYALCSHVDLSQLFYAIDNKYLPGLLRSGFYDLLISIHLASAKERKLMMKNEYIIPITSTTRKIRLYPDESKRHGLPGVGPRTCLKPGFRFSTPCFITTNEEHQKQSPEIPLELLKTKALGMLTEAVQCSGAHIRDPVGGSVEFQFVPVLKLIGTLLIMGVFDDDDVRQILLLIDPSVFGEHSGETEEGAEKEEVTQVEEKAVEAGEKASREAPIKGLLQTRLPESVKLQMCELLSYLCDCELQHRVEAIVAFGDIYVSKLQENQKFRYNELMQALNMSAALTARKTREFRSPPQEQINMLLNFQLGENCPCPEEIREELYDFHEDLLLHCGVPLEEEEEEEEDSSWTGKFCALVQRIKGPPKPEKEQPTEEEERCPTTLKELISQTMIRWAQEDQIQDAELVRMMFNLLRRQYDSIGELLQALRKTYTISQASVSDTISLLAALGQIRCLLSVRMGKEEELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGAEKLQIAFPKMVASCCRFLCYFCRISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELALGLEEPDLEKVVTYLAGCGLQSCPMLLAKGYPDVGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKLLIRRPECFGPALRGEGGNGLLAAMQGAIKISENPALDLPSQGYKREVSTEDDDDEEEIVHMGNAIMSFYSALIDLLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLPSLNKDGSVSEPDMAANFCPDHKAPMVLFLDRVYGIKDQTFLLHLLEVGFLPDLRASASLDTVSLSTTEAALALNRYICSAVLPLLTRCAPLFAGTEHYTSLIDSTLQTIYRLSKGRSLTKAQRDTIEECLLAICNHLRPSMLQQLLRRLVFDVPQLNEYCKMPLKLLTNHYEQCWKYYCLPSGWGSYGLAVEEELHLTEKLFWGIFDSLSHKRYDPDLFRMALPCLSAIAGALPPDYLDTRISATLEKQVSVDTDGNFDPKPINTVNFSLPEKLEYIVTKYAEHSHDRWACDKSQNGWKYGISLDENVKTHPLIRPFKTLTEKEKDIYRWPARESLKTMLAVGWTVERTKEGEALVQQRENEKLRSVSQASQGNSYSPAPLDLSNVVLSRELQGMVEVVAENYHNIWAKKKKLELESKGGGSHPLLVPYDTLTAKEKFRDREKAQDLFKFLQVNGIVVSRGMKDMELDASSMEKRFAYKFLKKVLKYVDSAQEFIAHLEAIVSSGKNEKSPHDQEIKFFAKVLLPLVDQYFINHRLYFLSSPLKPLSSSGYASHKEKEMVASLFCKLAALVRHRISLFGSDSTTMVSCLHILAQTLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTLENLKLGKFTHSRTQIKGVSQNINYTTVALLPILTSIFEHVAQHQFGVDLLLGDVQLSCYHILCSLYSLGTGKNIYVERQRPALGECLASLAAAIPVAFLEPTLNRYNPLSVFNTKTPRERSILGMPDTVEEMCPDIPQLEGLMKEINDLAESGARYTEMPHVIEVILPMLCNYLSYWWERGPEHLPPSAGPWCTKVTSEHLSVILGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLRSHFIPTLEKLKKKAIKTVQEEEQLRADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSNWLKSPDADSDQLFRMVAEIFILWCKSHNFKREEQNFVIQNEINNLAFLTGDSKSKMSKAMQVKSGGQDQERKKTKRRGDFYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKSRYSYKDTDEEVKEHLRNNLHLQEKSDDPAVKWQLNLYKDVLKSEEPSNPEKTVERVQRISAAVFHLEQVEQPLRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQRFWIETEEYSFEEKLVQDLAKSPKVEEEEEEEVEKQPDPLHQIILHFSRNALTERSKLEDDPLYTSYASMMAKSCQSGEDEDEDEDKEKTFEEKEMEKQKTLYQQARLHERGAAEMVLQMISASKGEMSPMVVETLKLGIAILNGGNAGVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKVLQNDEFTRDLFRFLQLLCEGHNSDFQNFLRTQMGNTTTVNVIISTVDYLLRLQESISDFYWYYSGKDIIDESGQHNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSTNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGIISKKEFQKAMEGQKQYTQSEIDFLLSCAEADENDMFNYIDFVDRFHEPAKDIGFNVAVLLTNLSEHMPNDSRLKCLLDPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISESDSADRPDEEEEEGGDSSYVLEVEGEEEEEEKSFECASAFAMACGSVKRNVANFLKRATLKNLRKQYRKVKKMTFKELVKVFFSFFWTLFMGLFHLLFTIVGGIIQVLWSTVFGGGLIEGAKNIRVTKILGDMPDPTQFGIHDDAMEAERAEVPEPGIATELVHFVKGQKGDADIMSDLFGLHPKKEGGLKHGPEVGLGDLSEIIGKDETPTLESTVRKKRKAQAAEMKAAHEAERKIESEKADMEDGEKEDTAKEEEQAEALWADVTKRKKRRCGQKVEKPEAFMANFFKGLEIYQTKLLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLEEETEDVANLWNSFNDEEEEEAVVFFVLQESTGYMAPTLRALAIIHTVISLVCVVGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKNALDFSPVEETKAEAASLVSWLSSIDMKYHVWKLGVVFTDNSFLYLAWYTTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDDDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG", "length": 4872, "header": "tr|A0ABI0NZM1-1|A0ABI0NZM1_BOVIN Isoform 1 of Ryanodine receptor 3 OS=Bos taurus OX=9913 GN=RYR3 PE=3 SV=1 CANONICAL=A0ABI0NZM1-1" }, "locus": { "chromosome": "10", "start_pos": 29286406, "end_pos": 28728710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145353.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145353.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105955.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105955.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZM1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZM1" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZM1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZM1" } ], "pmid": "" }, { "name": "ryanodine-sensitive calcium-release channel activity", "id": "GO:0005219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005219", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZM1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZM1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZM1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZM1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "sarcoplasmic reticulum membrane", "id": "GO:0033017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033017", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZM1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1280, "end_pos": 1282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1364, "end_pos": 1366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1853, "end_pos": 1855, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2121, "end_pos": 2123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2213, "end_pos": 2215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2607, "end_pos": 2609, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2991, "end_pos": 2993, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3276, "end_pos": 3278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3760, "end_pos": 3762, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3801, "end_pos": 3803, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3888, "end_pos": 3890, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4000, "end_pos": 4002, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4007, "end_pos": 4009, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4699, "end_pos": 4701, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MPF0-1", "A0AAA9RSQ6-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NZM1", "database": 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"Ensembl Transcript", "id": "ENSBTAT00000154716.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154716.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106222.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106222.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 35, "start_aa": "Thr", "end_pos": 35, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr35", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 63, 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"categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24264", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24264", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24264:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24264:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NSE8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSE8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYC2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYC2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZT4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZT4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6T2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6T2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6T2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P731", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P731", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P731-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P731-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQESRTREAAGVFVLGGVVPLHPLPLLGRYKGSPPATQVHFSTMHSLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLALPSACASAGTECLISGWGNTLSSGVNYPDLLQCLEAPLLSHADCEASYPGEITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS", "length": 290, "header": "tr|A0ABI0NZT4-1|A0ABI0NZT4_BOVIN Isoform 1 of trypsin OS=Bos taurus OX=9913 GN=PRSS2 PE=4 SV=1 CANONICAL=A0ABI0NZT4-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NSE8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT4/entry#A0ABI0NSE8-1", "sequence": { "sequence": "MRKTSVLIVRKRRNTTPVSYYPSASVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLALPSACASAGTECLISGWGNTLSSGVNYPDLLQCLEAPLLSHADCEASYPGEITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS", "length": 259, "header": "tr|A0ABI0NSE8-1|A0ABI0NZT4_BOVIN Computationally mapped isoform of trypsin OS=Bos taurus OX=9913 GN=PRSS2 PE=4 SV=1 CANONICAL=A0ABI0NZT4-1" }, "locus": { "chromosome": "4", "start_pos": 106075600, "end_pos": 106071112, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145031.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145031.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106977.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106977.1" } ] } }, { "isoform_ac": "A0ABI0NYC2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT4/entry#A0ABI0NYC2-1", "sequence": { "sequence": "SHPLVHPFWGFVGRVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLALPSACASAGTECLISGWGNTLSSGVNYPDLLQCLEAPLLSHADCEASYPGEITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS", "length": 248, "header": "tr|A0ABI0NYC2-1|A0ABI0NYC2_BOVIN Computationally mapped isoform of trypsin OS=Bos taurus OX=9913 GN=PRSS2 PE=4 SV=1 CANONICAL=A0ABI0NZT4-1" }, "locus": { "chromosome": "4", "start_pos": 106075600, "end_pos": 106072114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139581.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139581.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107202.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107202.1" } ] } }, { "isoform_ac": "A0ABI0NZT4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT4/entry#A0ABI0NZT4-1", "sequence": { "sequence": "MQESRTREAAGVFVLGGVVPLHPLPLLGRYKGSPPATQVHFSTMHSLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLALPSACASAGTECLISGWGNTLSSGVNYPDLLQCLEAPLLSHADCEASYPGEITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS", "length": 290, "header": "tr|A0ABI0NZT4-1|A0ABI0NZT4_BOVIN Isoform 1 of trypsin OS=Bos taurus OX=9913 GN=PRSS2 PE=4 SV=1 CANONICAL=A0ABI0NZT4-1" }, "locus": { "chromosome": "4", "start_pos": 106075600, "end_pos": 106071762, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140018.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140018.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105796.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105796.1" } ] } }, { "isoform_ac": "A0ABI0P6T2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT4/entry#A0ABI0P6T2-1", "sequence": { "sequence": "MQESRTREAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLALPSACASAGTECLISGWGNTLSSGVNYPDLLQCLEAPLLSHADCEASYPGEITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS", "length": 244, "header": "tr|A0ABI0P6T2-1|A0ABI0P6T2_BOVIN Computationally mapped isoform of trypsin OS=Bos taurus OX=9913 GN=PRSS2 PE=4 SV=1 CANONICAL=A0ABI0NZT4-1" }, "locus": { "chromosome": "4", "start_pos": 106075600, "end_pos": 106071762, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151271.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151271.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107283.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107283.1" } ] } }, { "isoform_ac": "A0ABI0P731-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT4/entry#A0ABI0P731-1", "sequence": { "sequence": "MAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLALPSACASAGTECLISGWGNTLSSGVNYPDLLQCLEAPLLSHADCEASYPGEITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS", "length": 234, "header": "tr|A0ABI0P731-1|A0ABI0P731_BOVIN Computationally mapped isoform of trypsin OS=Bos taurus OX=9913 GN=PRSS2 PE=4 SV=1 CANONICAL=A0ABI0NZT4-1" }, "locus": { "chromosome": "4", "start_pos": 106075600, "end_pos": 106071502, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141496.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141496.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107150.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107150.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZT4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZT4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NZT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZT4" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 287, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.21.4", "ec_name": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "3.4.21.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.21.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NUS3-1", "uniprot_ac": "A0ABI0NUS3", "uniprot_id": "A0ABI0NUS3_BOVIN", "mass": { "chemical_mass": 44948.0, "monoisotopic_mass": 44948.0 }, "refseq": {}, "gene_names": [ { "name": "C1H3orf38", "type": "recommended", "evidence": [ { "id": "A0ABI0NUS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUS3" } ] } ], "protein_names": [ { "name": "Chromosome 1 C3orf38 homolog", "type": "synonym", "evidence": [ { "id": "A0ABI0NUS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUS3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUS3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUS3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "C1H3orf38", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUS3", "locus": { "chromosome": "1", "start_pos": 36163235, "end_pos": 36156238, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007970", "url": "https://www.ensembl.org/id/ENSBTAG00000007970" } ] } } ], "crossref": [ { "id": "IPR026698", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026698", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21084", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21084", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21084:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21084:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NSQ1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUS3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUS3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRDTSLSSQQPGTTDRSTEFPECPHLLRLPPTGLEYPRLFSGERPERHFRYLLPRRRPAGPKEATLLAASSPPILGVEMTGLSYTEMEGCRNLLSLLDNDEIMALCDTITNRLVQPEDRQDAIRAILVYSQSVEELLRRRKVHREIIFKYLATQGVIIPPATEKHNLIQHAKDYWKKQLQPKLKETPEPVKTEDIRLSEQQEKEEKNAEKVDFRRLGEEFCQWFFELLNSQNPLLGPPQDEWGPQHFWHDVKLRFYYNTSEQNVIDYHGAEIVSLRLLSLVKEEYLFLSPNLDSHGLKYAASPHGLVMVGVAGTVHRGNTCLGIFEQIFGLIRCPFVENTWKIKFINLRIIGESSLAPGRLMKPAITFEPSDLEAFYNVNTLCGPVKYNSM", "length": 391, "header": "tr|A0ABI0NUS3-1|A0ABI0NUS3_BOVIN Isoform 1 of Chromosome 1 C3orf38 homolog OS=Bos taurus OX=9913 GN=C1H3orf38 PE=4 SV=1 CANONICAL=A0ABI0NUS3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NSQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUS3/entry#A0ABI0NSQ1-1", "sequence": { "sequence": "MLWANAACFVSKIQDAIRAILVYSQSVEELLRRRKVHREIIFKYLATQGVIIPPATEKHNLIQHAKDYWKKQLQPKLKETPEPVKTEDIRLSEQQEKEEKNAEKVDFRRLGEEFCQWFFELLNSQNPLLGPPQDEWGPQHFWHDVKLRFYYNTSEQNVIDYHGAEIVSLRLLSLVKEEYLFLSPNLDSHGLKYAASPHGLVMVGVAGTVHRGNTCLGIFEQIFGLIRCPFVENTWKIKFINLRIIGESSLAPGRLMKPAITFEPSDLEAFYNVNTLCGPVKYNSM", "length": 285, "header": "tr|A0ABI0NSQ1-1|A0ABI0NUS3_BOVIN Computationally mapped isoform of Chromosome 1 C3orf38 homolog OS=Bos taurus OX=9913 GN=C1H3orf38 PE=4 SV=1 CANONICAL=A0ABI0NUS3-1" }, "locus": { "chromosome": "1", "start_pos": 36162231, "end_pos": 36157072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139178.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139178.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106103.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106103.1" } ] } }, { "isoform_ac": "A0ABI0NUS3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUS3/entry#A0ABI0NUS3-1", "sequence": { "sequence": "MRDTSLSSQQPGTTDRSTEFPECPHLLRLPPTGLEYPRLFSGERPERHFRYLLPRRRPAGPKEATLLAASSPPILGVEMTGLSYTEMEGCRNLLSLLDNDEIMALCDTITNRLVQPEDRQDAIRAILVYSQSVEELLRRRKVHREIIFKYLATQGVIIPPATEKHNLIQHAKDYWKKQLQPKLKETPEPVKTEDIRLSEQQEKEEKNAEKVDFRRLGEEFCQWFFELLNSQNPLLGPPQDEWGPQHFWHDVKLRFYYNTSEQNVIDYHGAEIVSLRLLSLVKEEYLFLSPNLDSHGLKYAASPHGLVMVGVAGTVHRGNTCLGIFEQIFGLIRCPFVENTWKIKFINLRIIGESSLAPGRLMKPAITFEPSDLEAFYNVNTLCGPVKYNSM", "length": 391, "header": "tr|A0ABI0NUS3-1|A0ABI0NUS3_BOVIN Isoform 1 of Chromosome 1 C3orf38 homolog OS=Bos taurus OX=9913 GN=C1H3orf38 PE=4 SV=1 CANONICAL=A0ABI0NUS3-1" }, "locus": { "chromosome": "1", "start_pos": 36162231, "end_pos": 36156437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145246.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145246.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105008.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105008.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 258, "end_pos": 260 } ] }, "class_list": [], "section_stats": [ { "table_id": 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NZX5-1", "uniprot_ac": "A0ABI0NZX5", "uniprot_id": "A0ABI0NZX5_BOVIN", "mass": { "chemical_mass": 65503.0, "monoisotopic_mass": 65503.0 }, "refseq": { "ac": "XP_005219856", "name": "zinc finger protein 583 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219856" }, "gene_names": [ { "name": "ZNF583", "type": "recommended", "evidence": [ { "id": "A0ABI0NZX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX5" } ] }, { "name": "ZNF583", "type": "synonym", "evidence": [ { "id": "XP_005219856", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219856" } ] } ], "protein_names": [ { "name": "Zinc finger protein 583", "type": "recommended", "evidence": [ { "id": "A0ABI0NZX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX5/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 583 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005219856", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219856" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NT69", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT69#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0ABI0NXR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXR1#function" }, { "database": "UniProtKB", "id": "A0ABI0NZX5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZX5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF583", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX5", "locus": {} } ], "crossref": [ { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "789836", "url": "https://www.ncbi.nlm.nih.gov/gene/789836", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14196:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14196:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390:SF159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390:SF159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005219856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219856", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NT69", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT69-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXR1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZX5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZX5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEDLVTFRDVAVNFSQEEWEWLNPAQRSLYRTVMLDNYRSLVSLGISVSKPDVISLLEQGKEPWMVKEEGPRGACPGWEYTFKNKEFPSKQVIYEESSKVMMMGRSHLSYNLNCSSWRGDSKSKDWFKNQLGTQEVHASQLIVTHREILNEDHSNEYTKSWQTFHQDTIFDIKQKRNKHEPQKRSYRKKPIEMKHKKVYVEKKLLKCNECEKVFNQSSSLTLHQRIHTGEKPYACVECGKTFSQSANLAQHKRIHTGEKPYECKECRKAFSQNAHLAQHQRVHTGEKPYQCKECKKAFSQIAHLTQHQRVHTGERPFECIECGKAFSNGSFLAQHQRIHTGEKPYVCHVCAKAFSHRGYLIVHQRIHTGERPYECKECRKTFSQYAHLAQHQRVHTGEKPYECKVCRKAFSQIAYLDQHQRVHTGEKPYECIECGKAFSNSSSLAQHQRSHTGEKPYMCKECRKTFSQNAGLAQHQRIHTGEKPYECNICGKAFSYSGSLTLHQRIHTGERPYECKDCRKSFRQRAHLAHHERIHTMESFLTLSSPSASMSSQLPRPVGFIS", "length": 563, "header": "tr|A0ABI0NZX5-1|A0ABI0NZX5_BOVIN Isoform 1 of Zinc finger protein 583 OS=Bos taurus OX=9913 GN=ZNF583 PE=3 SV=1 CANONICAL=A0ABI0NZX5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NT69-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX5/entry#A0ABI0NT69-1", "sequence": { "sequence": "MQDLVTFRDVAVNFSQEEWEWLNPAQRSLYRTVMLDNYRSLVSLGISVSKPDVISLLEQGKEPWMVKEEGPRGACPGWEYTFKNKEFPSKQVIYEESSKVMMMGRSHLSYNLNCSSWRGDSKSKDWFKNQLGTQEVHASQLIVTHREILNEDHSNEYTKSWQTFHQDTIFDIKQKRNKHEPQKRSYRKKPIEMKHKKVYVEKKLLKCNECEKVFNQSSSLTLHQRIHTGEKPYACVECGKTFSQSANLAQHKRIHTGEKPYECKECRKAFSQNAHLAQHQRVHTGEKPYQCKECKKAFSQIAHLTQHQRVHTGERPFECIECGKAFSNGSFLAQHQRIHTGEKPYVCHVCAKAFSHRGYLIVHQRIHTGERPYECKECRKTFSQYAHLAQHQRVHTGEKPYECKVCRKAFSQIAYLDQHQRVHTGEKPYECIECGKAFSNSSSLAQHQRSHTGEKPYMCKECRKTFSQNAGLAQHQRIHTGEKPYECNICGKAFSYSGSLTLHQRIHTGERPYECKDCRKSFRQRAHLAHHERIHTMESFLTLSSPSASMSSQLPRPVGFIS", "length": 562, "header": "tr|A0ABI0NT69-1|A0ABI0NZX5_BOVIN Computationally mapped isoform of Zinc finger protein 583 OS=Bos taurus OX=9913 GN=ZNF583 PE=3 SV=1 CANONICAL=A0ABI0NZX5-1" }, "locus": { "chromosome": "18", "start_pos": 63773405, "end_pos": 63751744, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": 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583 OS=Bos taurus OX=9913 GN=ZNF583 PE=3 SV=1 CANONICAL=A0ABI0NZX5-1" }, "locus": { "chromosome": "18", "start_pos": 63758336, "end_pos": 63751744, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136436.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136436.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104889.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104889.1" } ] } }, { "isoform_ac": "A0ABI0NZX5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX5/entry#A0ABI0NZX5-1", "sequence": { "sequence": "MSEDLVTFRDVAVNFSQEEWEWLNPAQRSLYRTVMLDNYRSLVSLGISVSKPDVISLLEQGKEPWMVKEEGPRGACPGWEYTFKNKEFPSKQVIYEESSKVMMMGRSHLSYNLNCSSWRGDSKSKDWFKNQLGTQEVHASQLIVTHREILNEDHSNEYTKSWQTFHQDTIFDIKQKRNKHEPQKRSYRKKPIEMKHKKVYVEKKLLKCNECEKVFNQSSSLTLHQRIHTGEKPYACVECGKTFSQSANLAQHKRIHTGEKPYECKECRKAFSQNAHLAQHQRVHTGEKPYQCKECKKAFSQIAHLTQHQRVHTGERPFECIECGKAFSNGSFLAQHQRIHTGEKPYVCHVCAKAFSHRGYLIVHQRIHTGERPYECKECRKTFSQYAHLAQHQRVHTGEKPYECKVCRKAFSQIAYLDQHQRVHTGEKPYECIECGKAFSNSSSLAQHQRSHTGEKPYMCKECRKTFSQNAGLAQHQRIHTGEKPYECNICGKAFSYSGSLTLHQRIHTGERPYECKDCRKSFRQRAHLAHHERIHTMESFLTLSSPSASMSSQLPRPVGFIS", "length": 563, "header": "tr|A0ABI0NZX5-1|A0ABI0NZX5_BOVIN Isoform 1 of Zinc finger protein 583 OS=Bos taurus OX=9913 GN=ZNF583 PE=3 SV=1 CANONICAL=A0ABI0NZX5-1" }, "locus": { "chromosome": "18", "start_pos": 63763521, "end_pos": 63751744, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149823.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149823.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107337.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107337.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZX5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZX5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZX5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": 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Protein-glucosylgalactosylhydroxylysine glucosidase OS=Bos taurus OX=9913 GN=PGGHG PE=3 SV=1 CANONICAL=A0ABI0NZU1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NTV1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZU1/entry#A0ABI0NTV1-1", "sequence": { "sequence": "MEDAGEDATRFTARSLPSDPRLLATVTNAYLGTRVYHETLHVSGVYNGALGDTHRAILPSPLNVQLEAPAGTGEQLTKTYVLDTNTGSFVHTLEGPSFRASQRIYAHRTLPHVLAFSVSITRLAKGSWPVTVRLQSAFSPESPDLDLHLGPDFQGARYLCGRTLTPEQPGGAQQEVHMLWTPVPLALTLGEGQEDATWEFLTVVGGSQAEAQACLAEALQLQARHALYTAHAQAWAQLWADCGLDVEGPLALRQALRGALYYLLSALPQPGASGYVCHGLSPGGLSNGSRGECYWGHVFWDQDLWVLPGLLLLHPEAAKALLQYRIRTLSGALDNARSLGYQGAKFAWESAGSGLEVCPEAIYGTQEIHVNGAVVLAFQLYYHTTQDLELFREAGGWDVVRAVAEFWCSRVEWNPEEEKYHLKGVMPPDEYHPGVNNSVYTNVLVQNSLRFAAALAQDLGHPVPNQWLVVADKIKVPFDPKLNFHPEFDGYRPGEEVKQADVVLLGYPVPFPLSPHVRRQNLEIYEAVTSPHGPAMTWSMFAVGWMELKDPGRAWALLERSFANVTEPFKVWTENADGSGAVNFLTGMGGFLQAVLFGVTGFRITRAGLTFNPMCPVGISAVCVSGISYQGSRLDFSLSVGFVTVEVTAQAGPWAPSLEAELWPSRTRLPLPPDGPAASVCLRIPCMSRARLDVRVGL", "length": 698, "header": "tr|A0ABI0NTV1-1|A0ABI0NZU1_BOVIN Computationally mapped isoform of Protein-glucosylgalactosylhydroxylysine glucosidase OS=Bos taurus OX=9913 GN=PGGHG PE=3 SV=1 CANONICAL=A0ABI0NZU1-1" }, "locus": { "chromosome": "11", "start_pos": 82967009, "end_pos": 82957164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150429.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150429.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107062.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107062.1" } ] } }, { "isoform_ac": "A0ABI0NZU1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZU1/entry#A0ABI0NZU1-1", "sequence": { "sequence": 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"ec_number": "3.2.1.107", "activity": "(5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[collagen] + H2O = (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + D-glucose.", "evidence": [ { "id": "A0ABI0NZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZU1" } ] }, { "ec_number": "3.2.1.107", "activity": "", "evidence": [ { "id": "A0ABI0NZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZU1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZU1" }, { "id": "PF03632", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03632" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycoside hydrolase family 65 central catalytic", "eco_id": "ECO_0000259", "start_pos": 339, "end_pos": 540, "start_aa": "Asp", "end_aa": "Arg", 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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[provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377550" }, "gene_names": [ { "name": "OR2J3B", "type": "recommended", "evidence": [ { "id": "A0ABI0NUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUL0" } ] }, { "name": "OR2J3B", "type": "synonym", "evidence": [ { "id": "NP_001377550", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377550" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUL0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 2 subfamily J member 3B", "type": "synonym", "evidence": [ { "id": "NP_001377550", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377550" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377550", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377550" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUL0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUL0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUL0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUL0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2J3B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUL0", "locus": {} } ], "crossref": [ { "id": "cd15947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "789358", "url": "https://www.ncbi.nlm.nih.gov/gene/789358", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"https://www.ncbi.nlm.nih.gov/gene/532454", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377078", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377078", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NUM4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUM4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUM4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPKPRANGTAVTEFILLGLVETPGLWPAVFVLFLFAYLVTVGGNLSILAAILVEPKLHTPMYFFLGNLSVLDIGCITVTVPLMLGRLLSHKRTVPYAACLTQLFFFHLLVGVDCFLLTAMAYDRFLAICRPLTYSTRMSQTVQRILVAVSWACAFSNALTHTVAISTLNFCGPNVINHFYCDLPQLFQLSCSSTQLNELLLFGVGFIMAGTPLALVVTSYIHVAAAVLGIRSVEGRKKAFSTCGSHLTVVAIFYGSGIFNYMRLGSAKLSVKDKAVGIFNTVANPMLNPIIYSLRNPDVQGALRRVIKGRWSLE", "length": 315, "header": "tr|A0ABI0NUM4-1|A0ABI0NUM4_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR3A1 PE=3 SV=1 CANONICAL=A0ABI0NUM4-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NUM4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUM4/entry#A0ABI0NUM4-1", "sequence": { "sequence": "MQPKPRANGTAVTEFILLGLVETPGLWPAVFVLFLFAYLVTVGGNLSILAAILVEPKLHTPMYFFLGNLSVLDIGCITVTVPLMLGRLLSHKRTVPYAACLTQLFFFHLLVGVDCFLLTAMAYDRFLAICRPLTYSTRMSQTVQRILVAVSWACAFSNALTHTVAISTLNFCGPNVINHFYCDLPQLFQLSCSSTQLNELLLFGVGFIMAGTPLALVVTSYIHVAAAVLGIRSVEGRKKAFSTCGSHLTVVAIFYGSGIFNYMRLGSAKLSVKDKAVGIFNTVANPMLNPIIYSLRNPDVQGALRRVIKGRWSLE", "length": 315, "header": "tr|A0ABI0NUM4-1|A0ABI0NUM4_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR3A1 PE=3 SV=1 CANONICAL=A0ABI0NUM4-1" }, "locus": { "chromosome": "19", "start_pos": 24051201, "end_pos": 24050257, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144883.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144883.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107597.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107597.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUM4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUM4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUM4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUM4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUM4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUM4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NUM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUM4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 293, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 }, { "start_pos": 68, "end_pos": 70 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NUN5-1", "uniprot_ac": "A0ABI0NUN5", "uniprot_id": "A0ABI0NUN5_BOVIN", "mass": { "chemical_mass": 69034.0, "monoisotopic_mass": 69034.0 }, "refseq": {}, "gene_names": [ { "name": "OGFOD1", "type": "recommended", "evidence": [ { "id": "A0ABI0NUN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUN5" } ] } ], "protein_names": [ { "name": "Prolyl 3-hydroxylase OGFOD1", "type": "recommended", "evidence": [ { "id": "A0ABI0NUN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUN5/entry#names_and_taxonomy" } ] }, { "name": "2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0ABI0NUN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUN5/entry#names_and_taxonomy" } ] }, { "name": "uS12 prolyl 3-hydroxylase", "type": "synonym", "evidence": [ { "id": "A0ABI0NUN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUN5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUN5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUN5#function" }, { "database": "UniProtKB", "id": "ARBA00055047", "url": "https://www.uniprot.org/uniprotkb/ARBA00055047#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NUN5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUN5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OGFOD1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUN5", "locus": {} } ], "crossref": [ { "id": "IPR005123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039558", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039558", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051842", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051842", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12117:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12117:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "54156", "url": "https://www.rhea-db.org/rhea/54156", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NUN5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUN5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWP4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWP4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0H6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0H6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P336", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P336", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P336-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P336-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVSGAPIGKSGTGSTFLYLGAFYWVAVGKHRKGGILGIIVSLGKELLLQRAVDLVASEEMNGKRPAEPGSDRAGKKVKKEVMAKFSDAVTEETLKKQVAEAWSRRTPFRHEAIVMDMDPFLHCVIPNFIQSQNFLEGLQKELLNLDFHEKYNDLYKFQQSDDLKKRREPHICALRKILFEHFRSWISDISKIDLESTIDMSCAKYEFSDALLCHDDELEGRRIAFILYLVPPWDASLGGTLDLFSVDEHFQPKQIVKSLIPSWNTLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGPSLTRPPTYFEPLIARSPHIPQDHEILYDWINPTYLDMEYQAQIQEEFEESSEILLKEFLQPEKFAEVCEALERGRVEWSSRGPPNKRFYEKAEESQLPDILRDCMALFRSEAMFLLLSNFTGLKLHFLAPSEDEPEDKKERDAVSAAENTEEGTSHSSSEPENSWAATSDSSLQSEGPTDPEEDEAKKESSVPTCQGELRHWKTGHYTLIHDNSKTEFALDLLLYCGCEGWEPEYGGFTSYIAKGEDEELLTVNPENNSLALVYRDRETLKFVKHINHRSLEQKKSFPNRTGFWDFSFVYYE", "length": 603, "header": "tr|A0ABI0NUN5-1|A0ABI0NUN5_BOVIN Isoform 1 of Prolyl 3-hydroxylase OGFOD1 OS=Bos taurus OX=9913 GN=OGFOD1 PE=3 SV=1 CANONICAL=A0ABI0NUN5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NUN5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUN5/entry#A0ABI0NUN5-1", "sequence": { "sequence": "MAAVSGAPIGKSGTGSTFLYLGAFYWVAVGKHRKGGILGIIVSLGKELLLQRAVDLVASEEMNGKRPAEPGSDRAGKKVKKEVMAKFSDAVTEETLKKQVAEAWSRRTPFRHEAIVMDMDPFLHCVIPNFIQSQNFLEGLQKELLNLDFHEKYNDLYKFQQSDDLKKRREPHICALRKILFEHFRSWISDISKIDLESTIDMSCAKYEFSDALLCHDDELEGRRIAFILYLVPPWDASLGGTLDLFSVDEHFQPKQIVKSLIPSWNTLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGPSLTRPPTYFEPLIARSPHIPQDHEILYDWINPTYLDMEYQAQIQEEFEESSEILLKEFLQPEKFAEVCEALERGRVEWSSRGPPNKRFYEKAEESQLPDILRDCMALFRSEAMFLLLSNFTGLKLHFLAPSEDEPEDKKERDAVSAAENTEEGTSHSSSEPENSWAATSDSSLQSEGPTDPEEDEAKKESSVPTCQGELRHWKTGHYTLIHDNSKTEFALDLLLYCGCEGWEPEYGGFTSYIAKGEDEELLTVNPENNSLALVYRDRETLKFVKHINHRSLEQKKSFPNRTGFWDFSFVYYE", "length": 603, "header": "tr|A0ABI0NUN5-1|A0ABI0NUN5_BOVIN Isoform 1 of Prolyl 3-hydroxylase OGFOD1 OS=Bos taurus OX=9913 GN=OGFOD1 PE=3 SV=1 CANONICAL=A0ABI0NUN5-1" }, "locus": { "chromosome": "18", "start_pos": 24184804, "end_pos": 24155052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149440.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149440.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107517.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107517.1" } ] } }, { "isoform_ac": "A0ABI0NWP4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUN5/entry#A0ABI0NWP4-1", "sequence": { "sequence": "MAAVSGAPIGKSGTGSTFLYLGAFYWVAVGKHRKGGILGIIVSLGKELLLQRAVDLVASEEMNGKRPAEPGSDRAGKKVKKEVMAKFSDAVTEETLKKQVAEAWSRRTPFRHEAIVMDMDPFLHCVIPNFIQSQNFLEGLQKELLNLDFHEKYNDLYKFQQSDDLKKRREPHICALRKILFEHFRSWISDISKIDLESTIDMSCAKYEFSDALLCHDDELEGRRIAFILYLVPPWDASLGGTLDLFSVDEHFQPKQIVKSLIPSWNTLVFFEVSPVSFHQHEILYDWINPTYLDMEYQAQIQEEFEESSEILLKEFLQPEKFAEVCEALERGRVEWSSRGPPNKRFYEKAEESQLPDILRDCMALFRSEAMFLLLSNFTGLKLHFLAPSEDEPEDKKERDAVSAAENTEEGTSHSSSEPENSWAATSDSSLQSEGPTDPEEDEAKKESSVPTCQGELRHWKTGHYTLIHDNSKTEFALDLLLYCGCEGWEPEYGGFTSYIAKGEDEELLTVNPENNSLALVYRDRETLKFVKHINHRSLEQKKSFPNRTGFWDFSFVYYE", "length": 560, "header": "tr|A0ABI0NWP4-1|A0ABI0NWP4_BOVIN Computationally mapped isoform of 2-oxoglutarate and iron dependent oxygenase domain containing 1 OS=Bos taurus OX=9913 GN=OGFOD1 PE=4 SV=1 CANONICAL=A0ABI0NUN5-1" }, "locus": { "chromosome": "18", "start_pos": 24184804, "end_pos": 24155052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153505.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153505.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105439.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105439.1" } ] } }, { "isoform_ac": "A0ABI0P0H6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUN5/entry#A0ABI0P0H6-1", "sequence": { "sequence": "MNGKRPAEPGSDRAGKKVKKEVMAKFSDAVTEETLKKQVAEAWSRRTPFRHEAIVMDMDPFLHCVIPNFIQSQNFLEGLQKELLNLDFHEKYNDLYKFQQSDDLKKRREPHICALRKILFEHFRSWISDISKIDLESTIDMSCAKYEFSGWTGWISLQSRGTRGQIANIHWIIEKAREFQKNVYFCFIDYAKAFDCVDHKKLKNSERDALLCHDDELEGRRIAFILYLVPPWDASLGGTLDLFSVDEHFQPKQIVKSLIPSWNTLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGPSLTRPPTYFEPLIARSPHIPQDHEILYDWINPTYLDMEYQAQIQEEFEESSEILLKEFLQPEKFAEVCEALERGRVEWSSRGPPNKRFYEKAEESQLPDILRDCMALFRSEAMFLLLSNFTGLKLHFLAPSEDEPEDKKERDAVSAAENTEEGTSHSSSEPENSWAATSDSSLQSEGPTDPEEDEAKKESSVPTCQGELRHWKTGHYTLIHDNSKTEFALDLLLYCGCEGWEPEYGGFTSYIAKGEDEELLTVNPENNSLALVYRDRETLKFVKHINHRSLEQKKSFPNRTGFWDFSFVYYE", "length": 600, "header": "tr|A0ABI0P0H6-1|A0ABI0P0H6_BOVIN Computationally mapped isoform of Prolyl 3-hydroxylase OGFOD1 OS=Bos taurus OX=9913 GN=OGFOD1 PE=3 SV=1 CANONICAL=A0ABI0NUN5-1" }, "locus": { "chromosome": "18", "start_pos": 24184621, "end_pos": 24155052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154922.1", "url": 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NVE5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVE5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYM8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYM8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P167", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P167", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P167-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P167-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"MGDFSQRASPNIEIMLPRGKQSLWRITMEESRICRVGVKPDMLHHCQSNDIPQCNDSNYGSTSNKHSVEEDESSNITTKSRDLLSPVYCTQESREEPPGPGAGTDPSGGQQDSECHRNKEKILGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRNVQKQMKILQKKQAQIVKEKVNLQHEHNKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQFTLNEIQTQLKQHDVHSVKLRQENIELGEKLKKLIEQYALREEHIGKVFKHKELQQHLVDAKLQQTAQLIKEADKKHRREREFLLKEATESRHKYEEMKQQEIQLKQQLSLYMDKFEEFQTTMEKSNELFTTFRQEMEKMTKKMKNLEKEVIMWCTKWENNNKILLEMAEEKTVHDKEYRVFQIKLERLEKLYRALQMERNELNEKVQVLKEKPTPIIQPCSALDSQKEVITHSKRAPGGKLGVESSAVQMTLFMGSLLGIDSVD", "length": 498, "header": "tr|A0ABI0NVE5-1|A0ABI0NVE5_BOVIN Isoform 1 of Taxilin gamma OS=Bos taurus OX=9913 GN=LOC132344515 PE=3 SV=1 CANONICAL=A0ABI0NVE5-1" }, "locus": { "chromosome": "Y", "start_pos": 23319649, "end_pos": 23231548, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149818.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149818.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104679.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104679.1" } ] } }, { "isoform_ac": "A0ABI0NYM8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE5/entry#A0ABI0NYM8-1", "sequence": { "sequence": "MEESRICRVGVKPDMLHHCQSNDIPQCNDSNYGSTSNKHSVEEDESSNITTKSRDLLSPVYCTQESREEPPGPGAGTDPSGGQQDSECHRNKEKILGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRNVQKQMKILQKKQAQIVKEKVNLQHEHNKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQFTLNEIQTQLKQHDVHSVKLRQENIELGEKLKKLIEQYALREEHIGKVFKHKELQQHLVDAKLQQTAQLIKEADKKHRREREFLLKEATESRHKYEEMKQQEIQLKQQLSLYMDKFEEFQTTMEKSNELFTTFRQEMEKMTKKMKNLEKEVIMWCTKWENNNKILLEMAEEKTVHDKEYRVFQIKLERLEKLYRALQMERNELNEKVQKALYSGKLLDKG", "length": 426, "header": "tr|A0ABI0NYM8-1|A0ABI0NYM8_BOVIN Computationally mapped isoform of Taxilin gamma OS=Bos taurus OX=9913 GN=LOC132344515 PE=3 SV=1 CANONICAL=A0ABI0NVE5-1" }, "locus": { "chromosome": "Y", "start_pos": 23318787, "end_pos": 23230900, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145862.1", "url": 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"start_pos": 23318787, "end_pos": 23231548, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146117.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146117.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107609.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107609.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NVE5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVE5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" }, { 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10489:SF951", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10489:SF951", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NVF4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVF4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARAFGAVLPLNWFGDASSRQPSNSSLGNGSESTRPTWGPRSLDGLEGVAEAGAALALRALIAGAYLALCAVGLVGNVLVLVLVRSQQRRRHSLLNCFLLNLAATDLQFVLTLPFWAVDMVRDFSWPFGGAMCKVVLTLTVLNMYASGFFLSAMSVARYYAVARALRPRRPGTLWAVCVCSLLWATAVLATAPTALFATAASIGGERLCLLRFPDGGPDWLAFYHLQKITVAFVLPLVTLGTCSLLFLRFLRRQRVRWSSGVRHRRRSRVTRALACVLLVFVLCWLPNQALTFWGVLIKLNAVPWDRAYFLVQAYLFPVSICLAHSNSCLNPLLYCLLRRDFRQGLQELCGLAKHPADLRPGCPIDSRAPATGLSD", "length": 376, "header": "tr|A0ABI0NVF4-1|A0ABI0NVF4_BOVIN Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Bos taurus OX=9913 GN=LOC530472 PE=4 SV=1 CANONICAL=A0ABI0NVF4-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NVF4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVF4/entry#A0ABI0NVF4-1", "sequence": { "sequence": 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"endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZF3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZF3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "COPII receptor activity", "id": "GO:0097020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZF3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NYI2-1", "uniprot_ac": "A0ABI0NYI2", "uniprot_id": "A0ABI0NYI2_BOVIN", "mass": { "chemical_mass": 19701.0, "monoisotopic_mass": 19701.0 }, "refseq": {}, "gene_names": [ { "name": "CCL28", "type": "recommended", "evidence": [ { "id": "A0ABI0NYI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYI2" } ] } ], "protein_names": [ { "name": "C-C motif chemokine", "type": "recommended", "evidence": [ { "id": "A0ABI0NYI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYI2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF00048", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00048", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NVK6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NVK6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NVK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYI2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYI2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4L0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4L0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4L0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4L0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQTLSCSMRNLVLSPGIEPRPLPLGARSLNHLLDPQTHLCCFCTLGQMGMQQTGLALLALAACVAFRPSEAILPIASSCCTEVSHHISRRLLERVTTCRIQRADGDCDLAAVILHVKRRRVCVSPHNHVIKQWMNEQAAKKEAKGNICHKKRHHGRRNSKGAHRERQETHGHKTPY", "length": 176, "header": "tr|A0ABI0NYI2-1|A0ABI0NYI2_BOVIN Isoform 1 of C-C motif chemokine OS=Bos taurus OX=9913 GN=CCL28 PE=3 SV=1 CANONICAL=A0ABI0NYI2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NVK6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYI2/entry#A0ABI0NVK6-1", "sequence": { "sequence": "MDFSLWRKESGGHSLLWCRGFSSWCLLLWSTGPRQTHLCCFCTLGQMGMQQTGLALLALAACVAFRPSEAILPIASSCCTEVSHHISRRLLERVTTCRIQRADGDCDLAAVILHVKRRRVCVSPHNHVIKQWMNEQAAKKEAKGNICHKKRHHGRRNSKGAHRERQETHGHKTPY", "length": 175, "header": "tr|A0ABI0NVK6-1|A0ABI0NYI2_BOVIN Computationally mapped isoform of C-C motif chemokine OS=Bos taurus OX=9913 GN=CCL28 PE=3 SV=1 CANONICAL=A0ABI0NYI2-1" }, "locus": { "chromosome": "20", "start_pos": 31390136, "end_pos": 31367337, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144385.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144385.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104783.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104783.1" } ] } }, { "isoform_ac": "A0ABI0NYI2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYI2/entry#A0ABI0NYI2-1", "sequence": { "sequence": "MQTLSCSMRNLVLSPGIEPRPLPLGARSLNHLLDPQTHLCCFCTLGQMGMQQTGLALLALAACVAFRPSEAILPIASSCCTEVSHHISRRLLERVTTCRIQRADGDCDLAAVILHVKRRRVCVSPHNHVIKQWMNEQAAKKEAKGNICHKKRHHGRRNSKGAHRERQETHGHKTPY", "length": 176, "header": "tr|A0ABI0NYI2-1|A0ABI0NYI2_BOVIN Isoform 1 of C-C motif chemokine OS=Bos taurus OX=9913 GN=CCL28 PE=3 SV=1 CANONICAL=A0ABI0NYI2-1" }, "locus": { "chromosome": "20", "start_pos": 31390136, "end_pos": 31357067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139826.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139826.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105345.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105345.1" } ] } }, { "isoform_ac": "A0ABI0P4L0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYI2/entry#A0ABI0P4L0-1", "sequence": { "sequence": "AGASAPAPSLPTRGALAYRYVCWDSRQAILPIASSCCTEVSHHISRRLLERVTTCRIQRADGDCDLAAVILHVKRRRVCVSPHNHVIKQWMNEQAAKKEAKGNICHKKRHHGRRNSKGAHRERQETHGHKTPY", "length": 133, "header": "tr|A0ABI0P4L0-1|A0ABI0P4L0_BOVIN Computationally mapped isoform of C-C motif chemokine OS=Bos taurus OX=9913 GN=CCL28 PE=3 SV=1 CANONICAL=A0ABI0NYI2-1" }, "locus": { "chromosome": "20", "start_pos": 31390136, "end_pos": 31380232, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146907.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146907.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106675.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106675.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": 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{ "uniprot_canonical_ac": "A0ABI0NW24-1", "uniprot_ac": "A0ABI0NW24", "uniprot_id": "A0ABI0NW24_BOVIN", "mass": { "chemical_mass": 35134.0, "monoisotopic_mass": 35134.0 }, "refseq": { "ac": "NP_001377412", "name": "olfactory receptor family 6 subfamily C member 35", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377412" }, "gene_names": [ { "name": "OR6C35", "type": "recommended", "evidence": [ { "id": "A0ABI0NW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW24" } ] }, { "name": "OR6C2", "type": "synonym", "evidence": [ { "id": "NP_001377412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377412" } ] }, { "name": "OR6C35", "type": "synonym", "evidence": [ { "id": "NP_001377412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377412" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW24/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 6 subfamily C member 35", "type": "synonym", "evidence": [ { "id": "NP_001377412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377412" } ] }, { "name": "olfactory receptor, family 6, subfamily C, member 2", "type": "synonym", "evidence": [ { "id": "NP_001377412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377412" } ] }, { "name": "putative LOC787401 protein", "type": "synonym", "evidence": [ { "id": "NP_001377412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377412" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377412" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW24", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW24#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW24", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW24" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR6C35", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW24", "locus": {} } ], "crossref": [ { "id": "cd15912", "url": 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"Ensembl Peptide", "id": "ENSBTAP00000105214.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105214.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW90", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW90" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW90", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW90" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW90", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW90" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW90", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW90" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NW90", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW90" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NW90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW90" }, { "id": "PS50177", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50177" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NTF2", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 56, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NZ14-1", "uniprot_ac": "A0ABI0NZ14", "uniprot_id": "A0ABI0NZ14_BOVIN", "mass": { "chemical_mass": 70029.0, "monoisotopic_mass": 70029.0 }, "refseq": {}, "gene_names": [ { "name": "RLIM", "type": "recommended", "evidence": [ { "id": "A0ABI0NZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ14" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0ABI0NZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ14/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0ABI0NZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ14/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZ14", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ14" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RLIM", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ14", "locus": { "chromosome": "X", "start_pos": 76517923, "end_pos": 76498639, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015630", "url": "https://www.ensembl.org/id/ENSBTAG00000015630" } ] } } ], "crossref": [ { "id": "cd16674", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16674", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539871", "url": "https://www.ncbi.nlm.nih.gov/gene/539871", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539871", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539871", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR45931", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45931", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45931:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45931:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25914", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25914", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NW94", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NW94-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NW94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ14", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ14-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLGPRESSSGDFNIIFHLFIKMESSDCNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEEELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNPENENEPSARRSSGESMDNNSQRQMENPRSETTSARPPRSERNSTEALTGEAPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPDLLTRGLFAASGTRNASQGAGSSDTTGNGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPSGSVSSRNMERSESRNGRGGSGGSSSSGSSSSSSPSSSSNGESSETSSEVFEGSNEGSSSSGSSGARREGRHRAPVTFDESGSLPFLSLAQFFLLNEDDDDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASGNRESIV", "length": 633, "header": "tr|A0ABI0NZ14-1|A0ABI0NZ14_BOVIN Isoform 1 of RING-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=RLIM PE=3 SV=1 CANONICAL=A0ABI0NZ14-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NW94-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ14/entry#A0ABI0NW94-1", "sequence": { "sequence": "MESSDCNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEEELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNPENENEPSARRSSGESMDNNSQRQMENPRSETTSARPPRSERNSTEALTGEAPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPDLLTRGLFAASGTRNASQGAGSSDTTGNGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPSGSVSSRNMERSESRNGRGGSGGSSSSGSSSSSSPSSSSNGESSETSSEVFEGSNEGSSSSGSSGARREGRHRAPVTFDESGSLPFLSLAQFFLLNEDDDDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASGNRESIV", "length": 611, "header": "tr|A0ABI0NW94-1|A0ABI0NZ14_BOVIN Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=RLIM PE=3 SV=1 CANONICAL=A0ABI0NZ14-1" }, "locus": { "chromosome": "X", "start_pos": 76517113, "end_pos": 76513214, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148047.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148047.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104007.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104007.1" } ] } }, { "isoform_ac": "A0ABI0NZ14-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ14/entry#A0ABI0NZ14-1", "sequence": { "sequence": "MSLGPRESSSGDFNIIFHLFIKMESSDCNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEEELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNPENENEPSARRSSGESMDNNSQRQMENPRSETTSARPPRSERNSTEALTGEAPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPDLLTRGLFAASGTRNASQGAGSSDTTGNGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPSGSVSSRNMERSESRNGRGGSGGSSSSGSSSSSSPSSSSNGESSETSSEVFEGSNEGSSSSGSSGARREGRHRAPVTFDESGSLPFLSLAQFFLLNEDDDDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASGNRESIV", "length": 633, "header": "tr|A0ABI0NZ14-1|A0ABI0NZ14_BOVIN Isoform 1 of RING-type E3 ubiquitin transferase OS=Bos taurus OX=9913 GN=RLIM PE=3 SV=1 CANONICAL=A0ABI0NZ14-1" }, "locus": { "chromosome": "X", "start_pos": 76517113, "end_pos": 76509529, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142154.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142154.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105662.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105662.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:539871", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539871", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZ14", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ14" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZ14", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ14" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZ14", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" }, { "start_pos": 613, "end_pos": 615, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ14" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 579, "end_pos": 620, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376832" }, "gene_names": [ { "name": "OR9K1", "type": "recommended", "evidence": [ { "id": "A0ABI0NWH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWH1" } ] }, { "name": "OR9K1", "type": "synonym", "evidence": [ { "id": "NP_001376832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376832" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NWH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWH1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 9K2", "type": "synonym", "evidence": [ { "id": "NP_001376832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376832" } ] }, { "name": "olfactory receptor family 9 subfamily K member 1", "type": "synonym", "evidence": [ { "id": "NP_001376832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376832" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376832", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376832" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWH1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWH1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWH1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWH1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR9K1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWH1", "locus": {} } ], "crossref": [ { "id": "512340", "url": 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"start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NWH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWH1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 291, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NWK0-1", "uniprot_ac": "A0ABI0NWK0", "uniprot_id": "A0ABI0NWK0_BOVIN", "mass": { "chemical_mass": 77695.0, "monoisotopic_mass": 77695.0 }, "refseq": {}, "gene_names": [ { "name": "KLHDC7B", "type": "recommended", "evidence": [ { "id": "A0ABI0NWK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWK0" } ] } ], "protein_names": [ { "name": "Kelch domain containing 7B", "type": "recommended", "evidence": [ { "id": "A0ABI0NWK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWK0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWK0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWK0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KLHDC7B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWK0", "locus": { "chromosome": "5", "start_pos": 119853360, "end_pos": 119850778, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046800", "url": "https://www.ensembl.org/id/ENSBTAG00000046800" } ] } } ], "crossref": [ { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052310", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052310", "database": "InterPro", "categories": [ "Protein 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"MAQSASEAGGLAWGWDGDADEDWEDAALTLLALAVVAATALALHWFGSAQDQEAGGPASTALRPSQVEAAGPALPVKHKVSGAVEGHSSVQGKPGPPGHGQGSPAAAGAQDQEPLGGGSLAAAASPPLKTPAGEGASGGVLGPPETLRRKGKEAHRSGSALPCGSKGEGSSAPLLIHFTPRDPGREVEVWGEAGGVRGTAPDHRIGRDSRPWQQGRGSPASRGQSPGSRWGQVDSGRSGYRRRKLDALSLGSVVSVWDAVGAASCLPSGSQGLLFPQEPPPLCSLQTRPLMGVSERGLGESGPQATRGLALDSGATAGHRQGLGEKQEEARKLMMFLQRPGGWGVAEGPRKSRASVVALPRWLDLGSCLEALAFAQQHGDPGLAQETYAWMSDNLLHVLRDPSLYRQLSGADRERIVSLRTSRGPAVLGALVLPGLYRASRSELTRGSPAAEALAVGPAALPPPAYLHVFHPGENSWRPLTKVPQEAPLRGCGLCTLHNYLFLAGGVRGSGAEAVCCNEVFCYNPLTNIWSQVRPMQQARAQLKLVALDGLLYAIGGECLYSMECYDPRTDAWSPRAPLPAGAFPVAHDAVACQGDIYVTGGHLFHRLLRYRPTKDAWDECPYSASHRRSSDMVALGGFLYRFDLLRGVGAAVMRYNTVTSSWSRAASLPLPAPAPLRCAVLGNTIYCLNHQVTATFTVSEGTAQFQAKELQPFPLETKGVLCPFTLTLPARGPLQTAL", "length": 739, "header": "tr|A0ABI0NWK0-1|A0ABI0NWK0_BOVIN Isoform 1 of Kelch domain containing 7B OS=Bos taurus OX=9913 GN=KLHDC7B PE=4 SV=1 CANONICAL=A0ABI0NWK0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NWK0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWK0/entry#A0ABI0NWK0-1", "sequence": { "sequence": "MAQSASEAGGLAWGWDGDADEDWEDAALTLLALAVVAATALALHWFGSAQDQEAGGPASTALRPSQVEAAGPALPVKHKVSGAVEGHSSVQGKPGPPGHGQGSPAAAGAQDQEPLGGGSLAAAASPPLKTPAGEGASGGVLGPPETLRRKGKEAHRSGSALPCGSKGEGSSAPLLIHFTPRDPGREVEVWGEAGGVRGTAPDHRIGRDSRPWQQGRGSPASRGQSPGSRWGQVDSGRSGYRRRKLDALSLGSVVSVWDAVGAASCLPSGSQGLLFPQEPPPLCSLQTRPLMGVSERGLGESGPQATRGLALDSGATAGHRQGLGEKQEEARKLMMFLQRPGGWGVAEGPRKSRASVVALPRWLDLGSCLEALAFAQQHGDPGLAQETYAWMSDNLLHVLRDPSLYRQLSGADRERIVSLRTSRGPAVLGALVLPGLYRASRSELTRGSPAAEALAVGPAALPPPAYLHVFHPGENSWRPLTKVPQEAPLRGCGLCTLHNYLFLAGGVRGSGAEAVCCNEVFCYNPLTNIWSQVRPMQQARAQLKLVALDGLLYAIGGECLYSMECYDPRTDAWSPRAPLPAGAFPVAHDAVACQGDIYVTGGHLFHRLLRYRPTKDAWDECPYSASHRRSSDMVALGGFLYRFDLLRGVGAAVMRYNTVTSSWSRAASLPLPAPAPLRCAVLGNTIYCLNHQVTATFTVSEGTAQFQAKELQPFPLETKGVLCPFTLTLPARGPLQTAL", "length": 739, "header": "tr|A0ABI0NWK0-1|A0ABI0NWK0_BOVIN Isoform 1 of Kelch domain containing 7B OS=Bos taurus OX=9913 GN=KLHDC7B PE=4 SV=1 CANONICAL=A0ABI0NWK0-1" }, "locus": { "chromosome": "5", "start_pos": 119853357, "end_pos": 119849908, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138576.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138576.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104938.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104938.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140652.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140652.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105768.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105768.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NX61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX61" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NX61", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NX61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX61" }, { "id": "PS50127", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50127" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBC core", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 147, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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Specifically binds to scaffold/matrix attachment region DNA. Also binds single-stranded RNA. Enhances RNA unwinding activity of DDX39A. May participate in important transcriptional or translational control of cell growth, metabolism and carcinogenesis. Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. The TREX complex is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NXF1 pathway. 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{ "id": "A0ABI0P527", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P527", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P527-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P527-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRGWKMALSGGLRCCRRVLSWVPVLVIVLVVLWSYYAYVFELCLVTVLSPAEKVIYLIFYHAIFVFFTWTYWKSIFTLPQQPNQKFHLSYTDKERYENEERPEVQKQMLVDMAKKLPVYTRTGSGAVRFCDRCHLIKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAYSVLYCLYIATTVFSYFIKYWRGELPGVRSKFHVLFLLFVACMFFVSLVILFGYHCWLVSRNKTTLEAFCTPVFMSGPEKNGFNLGFVKNIQQVFGDNKKFWLIPIGSSPGDGHSFPMRSMNESQNPLLANEEPWEENEDDNRGPSISNEVYRVQCWKPF", "length": 339, "header": "tr|A0ABI0NXA5-1|A0ABI0NXA5_BOVIN Isoform 1 of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC15 PE=3 SV=1 CANONICAL=A0ABI0NXA5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NXA5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXA5/entry#A0ABI0NXA5-1", "sequence": { "sequence": "MRRGWKMALSGGLRCCRRVLSWVPVLVIVLVVLWSYYAYVFELCLVTVLSPAEKVIYLIFYHAIFVFFTWTYWKSIFTLPQQPNQKFHLSYTDKERYENEERPEVQKQMLVDMAKKLPVYTRTGSGAVRFCDRCHLIKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAYSVLYCLYIATTVFSYFIKYWRGELPGVRSKFHVLFLLFVACMFFVSLVILFGYHCWLVSRNKTTLEAFCTPVFMSGPEKNGFNLGFVKNIQQVFGDNKKFWLIPIGSSPGDGHSFPMRSMNESQNPLLANEEPWEENEDDNRGPSISNEVYRVQCWKPF", "length": 339, "header": "tr|A0ABI0NXA5-1|A0ABI0NXA5_BOVIN Isoform 1 of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC15 PE=3 SV=1 CANONICAL=A0ABI0NXA5-1" }, "locus": { "chromosome": "X", "start_pos": 75837438, "end_pos": 75746325, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138580.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138580.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104308.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104308.1" } ] } }, { "isoform_ac": "A0ABI0NZW6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXA5/entry#A0ABI0NZW6-1", "sequence": { "sequence": "MRRGWKMALSGGLRCCRRVLSWVPVLVIVLVVLWSYYAYVFELCLVIYLIFYHAIFVFFTWTYWKSIFTLPQQPNQKFHLSYTDKERYENEERPEVQKQMLVDMAKKLPVYTRTGSGAVRFCDRCHLIKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAYSVLYCLYIATTVFSYFIKYWRGELPGVRSKFHVLFLLFVACMFFVSLVILFGYHCWLVSRNKTTLEAFCTPVFMSGPEKNGFNLGFVKNIQQVFGDNKKFWLIPIGSSPGDGHSFPMRSMNESQNPLLANEEPWEENEDDNRDYPEGSSSLAVETET", "length": 328, "header": "tr|A0ABI0NZW6-1|A0ABI0NZW6_BOVIN Computationally mapped isoform of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC15 PE=3 SV=1 CANONICAL=A0ABI0NXA5-1" }, "locus": { "chromosome": "X", "start_pos": 75818504, "end_pos": 75746325, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151675.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151675.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104422.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104422.1" } ] } }, { "isoform_ac": "A0ABI0P527-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXA5/entry#A0ABI0P527-1", "sequence": { "sequence": "MRRGWKMALSGGLRCCRRVLSWVPVLVIVLVVLWSYYAYVFELCLVTVLSPAEKVIYLIFYHAIFVFFTWTYWKSIFTLPQQPNQKFHLSYTDKERYENEERPEVQKQMLVDMAKKLPVYTRTGSGAVRFCDRCHLIKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAYSVLYCLYIATTVFSYFIKYWRGELPGVRSKFHVLFLLFVACMFFVSLVILFGYHCWLVSRNKTTLEAFCTPVFMSGPEKNGFNLGFVKNIQQVFGDNKKFWLIPIGSSPGDGHSFPMRSMNESQNPLLANEEPWEENEDDNRDYPEGSSSLAVETET", "length": 337, "header": "tr|A0ABI0P527-1|A0ABI0P527_BOVIN Computationally mapped isoform of Palmitoyltransferase OS=Bos taurus OX=9913 GN=ZDHHC15 PE=3 SV=1 CANONICAL=A0ABI0NXA5-1" }, "locus": { "chromosome": "X", "start_pos": 75818504, "end_pos": 75746325, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139576.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139576.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105942.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105942.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:615421", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615421", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXA5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXA5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXA5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3X756-1", "E1BPA5-1", "F1MVC6-1", "E1B987-1", "E1BJK1-1", "F6R785-1", "A0AAA9TDW4-1", "A0AAA9TVJ9-1", "A0AAA9TM40-1", "E1B6X9-1", "E1BKA0-1", "E1BK60-1", "Q58CU4-1", "A2VDT6-1", "A0AAF6ZH94-1", "A0AAA9RZ07-1", "Q0VC89-1", "E1BLT8-1", "G3MXF3-1", "P15103-1", "Q2HJ95-1", "Q58DA8-1", "A0A3Q1M794-1", "A0A3Q1LVW6-1", "Q58DT3-1", "A0A3Q1M403-1", "A0ABI0NXA5-1" ], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LVW6", "gene_name": "ZDHHC13", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1LVW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVW6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1LVW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVW6" } ] } ] }, { "uniprot_ac": "A0A3Q1M403", "gene_name": "", "activity": [ { "ec_number": "6.3.1.2", "activity": "L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "A0A3Q1M403", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M403" } ] } ] }, { "uniprot_ac": "A0A3Q1M794", "gene_name": "ZDHHC3", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A3Q1M794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M794" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A3Q1M794", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M794" } ] } ] }, { "uniprot_ac": "A0AAA9RZ07", "gene_name": "ZDHHC8", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9RZ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ07" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9RZ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ07" } ] } ] }, { "uniprot_ac": "A0AAA9TDW4", "gene_name": "ZDHHC7", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9TDW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDW4" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9TDW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDW4" } ] } ] }, { "uniprot_ac": "A0AAA9TM40", "gene_name": "ZDHHC18", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9TM40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM40" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9TM40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM40" } ] } ] }, { "uniprot_ac": "A0AAA9TVJ9", "gene_name": "ZDHHC23", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAA9TVJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ9" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAA9TVJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ9" } ] } ] }, { "uniprot_ac": "A0AAF6ZH94", "gene_name": "ZDHHC9", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0AAF6ZH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZH94" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0AAF6ZH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZH94" } ] } ] }, { "uniprot_ac": "A0ABI0NXA5", "gene_name": "ZDHHC15", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0ABI0NXA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXA5" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0ABI0NXA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXA5" } ] } ] }, { "uniprot_ac": "A2VDT6", "gene_name": "ZDHHC21", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A2VDT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A2VDT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT6" } ] } ] }, { "uniprot_ac": "E1B6X9", "gene_name": "ZDHHC12", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1B6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X9" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1B6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X9" } ] } ] }, { "uniprot_ac": "E1B987", "gene_name": "ZDHHC22", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1B987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1B987", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B987" } ] } ] }, { "uniprot_ac": "E1BJK1", "gene_name": "ZDHHC17", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJK1" } ] } ] }, { "uniprot_ac": "E1BK60", "gene_name": "ZDHHC14", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BK60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BK60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK60" } ] } ] }, { "uniprot_ac": "E1BKA0", "gene_name": "ZDHHC4", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BKA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKA0" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BKA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKA0" } ] } ] }, { "uniprot_ac": "E1BLT8", "gene_name": "ZDHHC5", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BLT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLT8" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BLT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLT8" } ] } ] }, { "uniprot_ac": "E1BPA5", "gene_name": "ZDHHC24", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "E1BPA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA5" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "E1BPA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA5" } ] } ] }, { "uniprot_ac": "F1MVC6", "gene_name": "", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "F1MVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC6" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "F1MVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVC6" } ] } ] }, { "uniprot_ac": "F6R785", "gene_name": "ZDHHC1", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "F6R785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "F6R785", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R785" } ] } ] }, { "uniprot_ac": "G3MXF3", "gene_name": "ZDHHC2", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "G3MXF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXF3" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "G3MXF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXF3" } ] } ] }, { "uniprot_ac": "G3X756", "gene_name": "", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "G3X756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X756" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "G3X756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X756" } ] } ] }, { "uniprot_ac": "P15103", "gene_name": "GLUL", "activity": [ { "ec_number": "6.3.1.2", "activity": "L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+).", "evidence": [ { "id": "P15103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15103" } ] }, { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "P15103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15103" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "P15103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15103" } ] } ] }, { "uniprot_ac": "Q0VC89", "gene_name": "ZDHHC20", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q0VC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC89" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "Q0VC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC89" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "Q0VC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC89" } ] } ] }, { "uniprot_ac": "Q2HJ95", "gene_name": "ZDHHC6", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "Q2HJ95", "database": "UniProtKB", "url": 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"table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NXN3-1", "uniprot_ac": "A0ABI0NXN3", "uniprot_id": "A0ABI0NXN3_BOVIN", "mass": { "chemical_mass": 69580.0, "monoisotopic_mass": 69580.0 }, "refseq": {}, "gene_names": [ { "name": "PIGQ", "type": "recommended", "evidence": [ { "id": "A0ABI0NXN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN3" } ] } ], "protein_names": [ { "name": "Phosphatidylinositol glycan anchor biosynthesis class Q", "type": "synonym", "evidence": [ { "id": "A0ABI0NXN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXN3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PIGQ", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN3", "locus": {} } ], "crossref": [ { "id": "508048", "url": "https://www.ncbi.nlm.nih.gov/gene/508048", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21329:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21329:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NXN3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXN3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYZ8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4R7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4R7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4R7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRLLQLLWAQLSGPGMVLKAFFPTCCASADSGLLVGRWVPEQSSAVVLAVVHFPFIPVQVKELLAQVQQASQVGVAVLGTWCHRRQEPEESLGHFLEGLGTLFSHEPWLQLCRERGSKSWNCKATRRQGPTPLAPACEDQVMLIFYDQRKVLLSRLHPPAALPERQAGDATASAGGLAAVFDTVARSEVLFQSDRFDEGPVRLTHWQSEGVEASILVELAKRAAGPVCLLLACLLSLVSAASACRVFRPWPLSFIWSKLSTCEQLRHRLDQLTLVVSAHRAEGPAQLMRKANTLVSVLLDMALGLLLLSWLHRKDRFAHLAEALVPVADRVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEHILWHLGLSACLGLTVALSILSDIISLLTFHIYCFYVYGARLYSLKIHGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQVWRAGIPPRTGEGCPNWHQAALFIGTLLFTILIFLLPTTALYYLVFTLLRLLVVTVQGLVHLLVDLINSLPLYSLGLRLCRPYRLAAGVKFRVLEHEAGRPLRLLMQINPLPFSHVVRTYRLPSCGCHPKHSWGSLCRKLFFGELIYPWRQRGDKQD", "length": 618, "header": "tr|A0ABI0NXN3-1|A0ABI0NXN3_BOVIN Isoform 1 of Phosphatidylinositol glycan anchor biosynthesis class Q OS=Bos taurus OX=9913 GN=PIGQ PE=4 SV=1 CANONICAL=A0ABI0NXN3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NXN3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN3/entry#A0ABI0NXN3-1", "sequence": { "sequence": "MPRLLQLLWAQLSGPGMVLKAFFPTCCASADSGLLVGRWVPEQSSAVVLAVVHFPFIPVQVKELLAQVQQASQVGVAVLGTWCHRRQEPEESLGHFLEGLGTLFSHEPWLQLCRERGSKSWNCKATRRQGPTPLAPACEDQVMLIFYDQRKVLLSRLHPPAALPERQAGDATASAGGLAAVFDTVARSEVLFQSDRFDEGPVRLTHWQSEGVEASILVELAKRAAGPVCLLLACLLSLVSAASACRVFRPWPLSFIWSKLSTCEQLRHRLDQLTLVVSAHRAEGPAQLMRKANTLVSVLLDMALGLLLLSWLHRKDRFAHLAEALVPVADRVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEHILWHLGLSACLGLTVALSILSDIISLLTFHIYCFYVYGARLYSLKIHGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQVWRAGIPPRTGEGCPNWHQAALFIGTLLFTILIFLLPTTALYYLVFTLLRLLVVTVQGLVHLLVDLINSLPLYSLGLRLCRPYRLAAGVKFRVLEHEAGRPLRLLMQINPLPFSHVVRTYRLPSCGCHPKHSWGSLCRKLFFGELIYPWRQRGDKQD", "length": 618, "header": "tr|A0ABI0NXN3-1|A0ABI0NXN3_BOVIN Isoform 1 of Phosphatidylinositol glycan anchor biosynthesis class Q OS=Bos taurus OX=9913 GN=PIGQ PE=4 SV=1 CANONICAL=A0ABI0NXN3-1" }, "locus": { "chromosome": "25", "start_pos": 511083, "end_pos": 499033, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151171.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151171.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105603.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105603.1" } ] } }, { "isoform_ac": "A0ABI0NYZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN3/entry#A0ABI0NYZ8-1", "sequence": { "sequence": "MRSSSSPFFLSFNSGPGMVLKAFFPTCCASADSGLLVGRWVPEQSSAVVLAVVHFPFIPVQVKELLAQVQQASQVGVAVLGTWCHRRQEPEESLGHFLEGLGTLFSHEPWLQLCRERGSKSWNCKATRRQGPTPLAPACEDQVMLIFYDQRKVLLSRLHPPAALPERQAGDATASAGGLAAVFDTVARSEVLFQSDRFDEGPVRLTHWQSEGVEASILVELAKRAAGPVCLLLACLLSLVSAASACRVFRPWPLSFIWSKLSTCEQLRHRLDQLTLVVSAHRAEGPAQLMRKANTLVSVLLDMALGLLLLSWLHRKDRFAHLAEALVPVADRVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEHILWHLGLSACLGLTVALSILSDIISLLTFHIYCFYVYGARLYSLKIHGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILIFLLPTTALYYLVFTLLRLLVVTVQGLVHLLVDLINSLPLYSLGLRLCRPYRLAAGVKFRVLEHEAGRPLRLLMQINPLPFSHVVRTYRLPSCGCHPKHSWGSLCRKLFFGELIYPWRQRGDKQD", "length": 598, "header": "tr|A0ABI0NYZ8-1|A0ABI0NYZ8_BOVIN Computationally mapped isoform of Phosphatidylinositol glycan anchor biosynthesis class Q OS=Bos taurus OX=9913 GN=PIGQ PE=4 SV=1 CANONICAL=A0ABI0NXN3-1" }, "locus": { "chromosome": "25", "start_pos": 511083, "end_pos": 501213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139181.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139181.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106376.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106376.1" } ] } }, { "isoform_ac": "A0ABI0P4R7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN3/entry#A0ABI0P4R7-1", "sequence": { "sequence": "MPRLLQLLWAQLSGPGMVLKAFFPTCCASADSGLLVGRWVPEQSSAVVLAVVHFPFIPVQVKELLAQVQQASQVGVAVLGTWCHRRQEPEESLGHFLEGLGTLFSHEPWLQLCRERGSKSWNCKATRRQGPTPLAPACEDQVMLIFYDQRKVLLSRLHPPAALPERQAGDATASAGGLAAVFDTVARSEVLFQSDRFDEGPVRLTHWQSEGVEASILVELAKRAAGPVCLLLACLLSLVSAASACRVFRPWPLSFIWSKLSTCEQLRHRLDQLTLVVSAHRAEGPAQLMRKANTLVSVLLDMALGLLLLSWLHRKDRFAHLAEALVPVADRVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEHILWHLGLSACLGLTVALSILSDIISLLTFHIYCFYVYGARLYSLKIHGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILIFLLPTTALYYLVFTLLRLLVVTVQGLVHLLVDLINSLPLYSLGLRLCRPYRLAAGVKFRVLEHEAGRPLRLLMQINPLPFSHVVRTYRLPSCGCHPKHSWGSLCRKLFFGELIYPWRQRGDKQD", "length": 597, "header": "tr|A0ABI0P4R7-1|A0ABI0P4R7_BOVIN Computationally mapped isoform of Phosphatidylinositol glycan anchor biosynthesis class Q OS=Bos taurus OX=9913 GN=PIGQ PE=4 SV=1 CANONICAL=A0ABI0NXN3-1" }, "locus": { "chromosome": "25", "start_pos": 511083, "end_pos": 499033, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144341.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144341.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106182.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106182.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXN3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXN3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NXN9-1", "uniprot_ac": "A0ABI0NXN9", "uniprot_id": "A0ABI0NXN9_BOVIN", "mass": { "chemical_mass": 56944.0, "monoisotopic_mass": 56944.0 }, "refseq": {}, "gene_names": [ { "name": "LOC132344514", "type": "recommended", "evidence": [ { "id": "A0ABI0NXN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN9" } ] } ], "protein_names": [ { "name": "Preferentially expressed antigen in melanoma", "type": "recommended", "evidence": [ { "id": "A0ABI0NXN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXN9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC132344514", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN9", "locus": {} } ], "crossref": [ { "id": "IPR026271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14224:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14224:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NXN9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXN9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYLQDSFQRRFFRMNVQAPPRLLELGAQCLLRNEALAIMALEELPIELFPPLFMEAFAGRHTEALKAMVQAWPFPCLPLGALMQDHQPHLDTFQAALDGLDVLLAQEVRPRRWKLQVLDLRRKTHQDFWTLWSGMKVSVCSLLEPEPAQPMQKRCRVEAQAGLKPEQAPVEVLVDLCIKEDTLDETLSYLLKKAKKRGKLLHIRCQKLRIFTMPMHSIRKILKVVQLDSIQDLEVNCIWKLATLSRFLPHLGRMGNLRRLLLSRIHILPHTTPDQENCVNQLSAQFLNLPHLQELYLDSISFLEGRLHQVLRCLNTPLETLSITNCLISESDLTYLSQCPSVSLLKDLGLSGVNLTSLNLESLQVLIERTSATLQELDLDECGIMDSQFSALLPSLSGCSQLTTFSFCGNPISMAVLESLLHHTMGLSKLSHVLYPAPLESYEDVHGTLHLGLLAQLHARLKQLLCKSGRPSMFWVSASPCPHCGDQILYDTEPILCPCYLPD", "length": 503, "header": "tr|A0ABI0NXN9-1|A0ABI0NXN9_BOVIN Isoform 1 of Preferentially expressed antigen in melanoma OS=Bos taurus OX=9913 GN=LOC132344514 PE=3 SV=1 CANONICAL=A0ABI0NXN9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NXN9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXN9/entry#A0ABI0NXN9-1", "sequence": { "sequence": "MYLQDSFQRRFFRMNVQAPPRLLELGAQCLLRNEALAIMALEELPIELFPPLFMEAFAGRHTEALKAMVQAWPFPCLPLGALMQDHQPHLDTFQAALDGLDVLLAQEVRPRRWKLQVLDLRRKTHQDFWTLWSGMKVSVCSLLEPEPAQPMQKRCRVEAQAGLKPEQAPVEVLVDLCIKEDTLDETLSYLLKKAKKRGKLLHIRCQKLRIFTMPMHSIRKILKVVQLDSIQDLEVNCIWKLATLSRFLPHLGRMGNLRRLLLSRIHILPHTTPDQENCVNQLSAQFLNLPHLQELYLDSISFLEGRLHQVLRCLNTPLETLSITNCLISESDLTYLSQCPSVSLLKDLGLSGVNLTSLNLESLQVLIERTSATLQELDLDECGIMDSQFSALLPSLSGCSQLTTFSFCGNPISMAVLESLLHHTMGLSKLSHVLYPAPLESYEDVHGTLHLGLLAQLHARLKQLLCKSGRPSMFWVSASPCPHCGDQILYDTEPILCPCYLPD", "length": 503, "header": "tr|A0ABI0NXN9-1|A0ABI0NXN9_BOVIN Isoform 1 of Preferentially expressed antigen in melanoma OS=Bos taurus OX=9913 GN=LOC132344514 PE=3 SV=1 CANONICAL=A0ABI0NXN9-1" }, "locus": { "chromosome": "Y", "start_pos": 22897318, "end_pos": 22893394, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152754.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152754.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106062.1", "url": 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[provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377522" }, "gene_names": [ { "name": "OR4D2F", "type": "recommended", "evidence": [ { "id": "A0ABI0NXP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXP5" } ] }, { "name": "OR4D2F", "type": "synonym", "evidence": [ { "id": "NP_001377522", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377522" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 4 subfamily D member 2F", "type": "synonym", "evidence": [ { "id": "A0ABI0NXP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXP5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4D2", "type": "synonym", "evidence": [ { "id": "NP_001377522", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377522" } ] }, { "name": "olfactory receptor family 4 subfamily D member 2F", "type": "synonym", "evidence": [ { "id": "NP_001377522", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377522" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377522" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXP5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXP5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXP5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXP5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4D2F", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXP5", "locus": {} } ], "crossref": [ { "id": "cd15936", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377719", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377719", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NXW2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXW2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPYGNGNLSVMPLQEFVLDGFGGGPQTQALLFTLFLVLYLVDVLGNLTMIVVITLDARLHSPMYFFLKNLSFLDLCYSSVIYPKALFDLMSSTKVITFAGCVTQFFFFSTMITTEGFLLAVMAYDRFMAICNPLLYPISMRPSVCALLMLGCYCGGSFNSILQASFTFSLPFCSSNHIDHFHCDVPPLLKLACADTTTNELVMFGLCGLVIVGTILVVLVSYGYITVTILRIRSGGGRHKLFSTCGSHMTAVSLLYGTAFIMYAQPGALQSMEQGKVVSVFYTLVIPMLNPLIYSLRNKDVKDALWRLSQKHTAT", "length": 316, "header": "tr|A0ABI0NXW2-1|A0ABI0NXW2_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR9S43B PE=3 SV=1 CANONICAL=A0ABI0NXW2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NXW2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW2/entry#A0ABI0NXW2-1", "sequence": { "sequence": "MSPYGNGNLSVMPLQEFVLDGFGGGPQTQALLFTLFLVLYLVDVLGNLTMIVVITLDARLHSPMYFFLKNLSFLDLCYSSVIYPKALFDLMSSTKVITFAGCVTQFFFFSTMITTEGFLLAVMAYDRFMAICNPLLYPISMRPSVCALLMLGCYCGGSFNSILQASFTFSLPFCSSNHIDHFHCDVPPLLKLACADTTTNELVMFGLCGLVIVGTILVVLVSYGYITVTILRIRSGGGRHKLFSTCGSHMTAVSLLYGTAFIMYAQPGALQSMEQGKVVSVFYTLVIPMLNPLIYSLRNKDVKDALWRLSQKHTAT", "length": 316, "header": "tr|A0ABI0NXW2-1|A0ABI0NXW2_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR9S43B PE=3 SV=1 CANONICAL=A0ABI0NXW2-1" }, "locus": { "chromosome": "3", "start_pos": 119168978, "end_pos": 119168031, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151199.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151199.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104968.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104968.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXW2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXW2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXW2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NXW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXW2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 295, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 47, "end_pos": 49 }, { "start_pos": 70, "end_pos": 72 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NXX1-1", "uniprot_ac": "A0ABI0NXX1", "uniprot_id": "A0ABI0NXX1_BOVIN", "mass": { "chemical_mass": 80439.0, "monoisotopic_mass": 80439.0 }, "refseq": { "ac": "XP_002707864", "name": "BBSome complex assembly protein BBS10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002707864" }, "gene_names": [ { "name": "BBS10", "type": "recommended", "evidence": [ { "id": "A0ABI0NXX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXX1" } ] }, { "name": "BBS10", "type": "synonym", "evidence": [ { "id": "XP_002707864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002707864" } ] } ], "protein_names": [ { "name": "BBSome complex assembly protein BBS10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002707864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002707864" } ] }, { "name": "Bardet-Biedl syndrome 10", "type": "synonym", "evidence": [ { "id": "A0ABI0NXX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXX1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXX1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXX1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BBS10", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXX1", "locus": {} } ], "crossref": [ { "id": "538638", "url": "https://www.ncbi.nlm.nih.gov/gene/538638", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14667", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14667", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14667:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14667:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00118", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00118", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002707864", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002707864", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NXX1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXX1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2U0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2U0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2U0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGSVTVALHVAEVLETIVSGCLGPEGRQVLCTKPTGEVLLSRDGGCLLKALHLEHPVARVMVACVSSHLRKTGDGAKTFIIFLCHLLRGLREITDKEKDSFLFENIQTCGRHWKNCCRWKFISQAFLTFQTQILDYVMDHYLSRHFLSIFSSCTKERTLCRSSLEMLLGAYFCGRVGRNNQNLMSQLMCDYVFKCTACESRFEEVLELVDDCFVELKVGVTGLPVSDSRIIAGLVLQRDFSVYCPADGDIRIVIVTETIQPLFSISGSEFTLNSEAQFQTSQFWITERTKAIVKHLQNQNVKLLLSTVKQPDLVIYCAGLNGISVVECLSSEELSLIQRVIGLAPFVLPEASSQYELSHTALAKFCKPLILRSKRFVHLGLMSTCSFAPHCIALCAPVQGLVEQHENALHGAFKMLRQAFKDLDLNCVTQTSDQSCTSGPCIYKNSRESNELPKIVNSSIQRSYQDTVVKKKGELAKTQTNLKVCSNLIVPSVKLEQNVLCSTPKVAVTDSYQTDETLRCSSPNKGRIMDDQEPFIESNSANSKPENTRRGISYENLQVTKLARKDSILPLRYKSLETCTSQSYYSSSIPAGCVLPVGGNFEILLHYYLLNYAKKCQQSEQTMVSRIIANAILGVPKILYKSKKGNYSFPQVYVRALQALQTNQPMISNQTGLESVAGKYQLLTSVLQCLTNILTVDLVINIKRQPQEVYDQDSEEEL", "length": 721, "header": "tr|A0ABI0NXX1-1|A0ABI0NXX1_BOVIN Isoform 1 of Bardet-Biedl syndrome 10 OS=Bos taurus OX=9913 GN=BBS10 PE=4 SV=1 CANONICAL=A0ABI0NXX1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NXX1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXX1/entry#A0ABI0NXX1-1", "sequence": { "sequence": "MAAAGSVTVALHVAEVLETIVSGCLGPEGRQVLCTKPTGEVLLSRDGGCLLKALHLEHPVARVMVACVSSHLRKTGDGAKTFIIFLCHLLRGLREITDKEKDSFLFENIQTCGRHWKNCCRWKFISQAFLTFQTQILDYVMDHYLSRHFLSIFSSCTKERTLCRSSLEMLLGAYFCGRVGRNNQNLMSQLMCDYVFKCTACESRFEEVLELVDDCFVELKVGVTGLPVSDSRIIAGLVLQRDFSVYCPADGDIRIVIVTETIQPLFSISGSEFTLNSEAQFQTSQFWITERTKAIVKHLQNQNVKLLLSTVKQPDLVIYCAGLNGISVVECLSSEELSLIQRVIGLAPFVLPEASSQYELSHTALAKFCKPLILRSKRFVHLGLMSTCSFAPHCIALCAPVQGLVEQHENALHGAFKMLRQAFKDLDLNCVTQTSDQSCTSGPCIYKNSRESNELPKIVNSSIQRSYQDTVVKKKGELAKTQTNLKVCSNLIVPSVKLEQNVLCSTPKVAVTDSYQTDETLRCSSPNKGRIMDDQEPFIESNSANSKPENTRRGISYENLQVTKLARKDSILPLRYKSLETCTSQSYYSSSIPAGCVLPVGGNFEILLHYYLLNYAKKCQQSEQTMVSRIIANAILGVPKILYKSKKGNYSFPQVYVRALQALQTNQPMISNQTGLESVAGKYQLLTSVLQCLTNILTVDLVINIKRQPQEVYDQDSEEEL", "length": 721, "header": "tr|A0ABI0NXX1-1|A0ABI0NXX1_BOVIN Isoform 1 of Bardet-Biedl syndrome 10 OS=Bos taurus OX=9913 GN=BBS10 PE=4 SV=1 CANONICAL=A0ABI0NXX1-1" }, "locus": { "chromosome": "5", "start_pos": 5831731, "end_pos": 5828984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154611.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154611.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104682.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104682.1" } ] } }, { "isoform_ac": "A0ABI0P2U0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXX1/entry#A0ABI0P2U0-1", "sequence": { "sequence": "MVKRVMVACVSSHLRKTGDGAKTFIIFLCHLLRGLREITDKEKDSFLFENIQTCGRHWKNCCRWKFISQAFLTFQTQILDYVMDHYLSRHFLSIFSSCTKERTLCRSSLEMLLGAYFCGRVGRNNQNLMSQLMCDYVFKCTACESRFEEVLELVDDCFVELKVGVTGLPVSDSRIIAGLVLQRDFSVYCPADGDIRIVIVTETIQPLFSISGSEFTLNSEAQFQTSQFWITERTKAIVKHLQNQNVKLLLSTVKQPDLVIYCAGLNGISVVECLSSEELSLIQRVIGLAPFVLPEASSQYELSHTALAKFCKPLILRSKRFVHLGLMSTCSFAPHCIALCAPVQGLVEQHENALHGAFKMLRQAFKDLDLNCVTQTSDQSCTSGPCIYKNSRESNELPKIVNSSIQRSYQDTVVKKKGELAKTQTNLKVCSNLIVPSVKLEQNVLCSTPKVAVTDSYQTDETLRCSSPNKGRIMDDQEPFIESNSANSKPENTRRGISYENLQVTKLARKDSILPLRYKSLETCTSQSYYSSSIPAGCVLPVGGNFEILLHYYLLNYAKKCQQSEQTMVSRIIANAILGVPKILYKSKKGNYSFPQVYVRALQALQTNQPMISNQTGLESVAGKYQLLTSVLQCLTNILTVDLVINIKRQPQEVYDQDSEEEL", "length": 663, "header": "tr|A0ABI0P2U0-1|A0ABI0P2U0_BOVIN Computationally mapped isoform of Bardet-Biedl syndrome 10 OS=Bos taurus OX=9913 GN=BBS10 PE=4 SV=1 CANONICAL=A0ABI0NXX1-1" }, "locus": { "chromosome": "5", "start_pos": 5831339, "end_pos": 5828984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": 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"tr|A0ABI0NXZ4-1|A0ABI0NXZ4_BOVIN Isoform 1 of Zinc finger matrin-type protein 3 OS=Bos taurus OX=9913 GN=ZMAT3 PE=4 SV=1 CANONICAL=A0ABI0NXZ4-1" }, "locus": { "chromosome": "1", "start_pos": 88037605, "end_pos": 88010226, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146066.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146066.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104707.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104707.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXZ4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ4" } ], "pmid": "" }, { "name": "nucleic acid 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"end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0NXZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ4" }, { "id": "SM00451", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00451" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U1-type", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 101, "start_aa": "Cys", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 244, "end_pos": 246 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ5", "locus": {} } ], "crossref": [ { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NXZ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVSDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNVLNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIVPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGIIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPLGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTYTVFKCHSCLKVLKNVEFMNHMNHHLELERLRCDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYRQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPERKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPS", "length": 543, "header": "tr|A0ABI0NXZ5-1|A0ABI0NXZ5_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NXZ5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NXZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ5/entry#A0ABI0NXZ5-1", "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVSDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNVLNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIVPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGIIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPLGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTYTVFKCHSCLKVLKNVEFMNHMNHHLELERLRCDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYRQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPERKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPS", "length": 543, "header": "tr|A0ABI0NXZ5-1|A0ABI0NXZ5_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NXZ5-1" }, "locus": { "chromosome": "Y", "start_pos": 45337519, "end_pos": 45335891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141365.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141365.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106158.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106158.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXZ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXZ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXZ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NXZ5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXZ5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 343, "end_pos": 371, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 68, 96 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 523, "end_pos": 525 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NYL0-1", "uniprot_ac": "A0ABI0NYL0", "uniprot_id": "A0ABI0NYL0_BOVIN", "mass": { "chemical_mass": 34898.0, "monoisotopic_mass": 34898.0 }, "refseq": { "ac": "NP_001377515", "name": "olfactory receptor family 4 subfamily D member 2G", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NYR1-1", "uniprot_ac": "A0ABI0NYR1", "uniprot_id": "A0ABI0NYR1_BOVIN", "mass": { "chemical_mass": 35040.0, "monoisotopic_mass": 35040.0 }, "refseq": {}, "gene_names": [ { "name": "OR13P11", "type": "recommended", "evidence": [ { "id": "A0ABI0NYR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR1" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 13 subfamily P member 11", "type": "synonym", "evidence": [ { "id": "A0ABI0NYR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR13P11", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR1", "locus": {} } ], "crossref": [ { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NYR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYR1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQELNQSTVTEFILMGFASNPRTNPLLFTFFLVFYLLILVSNSLLITLIHQDTRLHTPMYFFISVLSMLDMCYTTTTVPQMLVHILSKKRAISFARCVAQMYIFLLFGIIEYCLFSIISVDRYVAICHPLRYKVIMSPWVCLLMVGICAAYGVVGGLSYTFFAMCLSYCGPNEIDHYFCEVPAVLKLACADTSLNDLVDFITGFNVIVVPLSLIVLVYVNIFATIMKIRSAQGRIKAFSTCTSHITVVTMFAIPCIITYMSPGSDSLSNSGKKMALFYNIATAFLNPVIYSLRNKDVKNAFLKLMGRGRAPE", "length": 312, "header": "tr|A0ABI0NYR1-1|A0ABI0NYR1_BOVIN Isoform 1 of Olfactory receptor family 13 subfamily P member 11 OS=Bos taurus OX=9913 GN=OR13P11 PE=3 SV=1 CANONICAL=A0ABI0NYR1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NYR1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR1/entry#A0ABI0NYR1-1", "sequence": { "sequence": "MQELNQSTVTEFILMGFASNPRTNPLLFTFFLVFYLLILVSNSLLITLIHQDTRLHTPMYFFISVLSMLDMCYTTTTVPQMLVHILSKKRAISFARCVAQMYIFLLFGIIEYCLFSIISVDRYVAICHPLRYKVIMSPWVCLLMVGICAAYGVVGGLSYTFFAMCLSYCGPNEIDHYFCEVPAVLKLACADTSLNDLVDFITGFNVIVVPLSLIVLVYVNIFATIMKIRSAQGRIKAFSTCTSHITVVTMFAIPCIITYMSPGSDSLSNSGKKMALFYNIATAFLNPVIYSLRNKDVKNAFLKLMGRGRAPE", "length": 312, "header": "tr|A0ABI0NYR1-1|A0ABI0NYR1_BOVIN Isoform 1 of Olfactory receptor family 13 subfamily P member 11 OS=Bos taurus OX=9913 GN=OR13P11 PE=3 SV=1 CANONICAL=A0ABI0NYR1-1" }, "locus": { "chromosome": "3", "start_pos": 102985231, "end_pos": 102929907, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151772.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151772.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105478.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105478.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYR1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NYR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NYR9-1", "uniprot_ac": "A0ABI0NYR9", "uniprot_id": "A0ABI0NYR9_BOVIN", "mass": { "chemical_mass": 80375.0, "monoisotopic_mass": 80375.0 }, "refseq": { "ac": "XP_002691170", "name": "probable E3 ubiquitin-protein ligase IRF2BPL", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691170" }, "gene_names": [ { "name": "IRF2BPL", "type": "recommended", "evidence": [ { "id": "A0ABI0NYR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR9" } ] }, { "name": "IRF2BPL", "type": "synonym", "evidence": [ { "id": "XP_002691170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691170" } ] } ], "protein_names": [ { "name": "Interferon regulatory factor 2 binding protein like", "type": "synonym", "evidence": [ { "id": "A0ABI0NYR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR9/entry#names_and_taxonomy" } ] }, { "name": "probable E3 ubiquitin-protein ligase IRF2BPL", "type": "synonym", "evidence": [ { "id": "XP_002691170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691170" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NYR9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IRF2BPL", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR9", "locus": { "chromosome": "10", "start_pos": 88235845, "end_pos": 88238861, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000025329", "url": "https://www.ensembl.org/id/ENSBTAG00000025329" } ] } } ], "crossref": [ { "id": "cd16717", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16717", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "613845", "url": "https://www.ncbi.nlm.nih.gov/gene/613845", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022750", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022750", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044882", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044882", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613845", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613845", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR10816", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10816", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10816:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10816:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11261", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11261", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002691170", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691170", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NYR9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYR9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAAQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRAHGCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAQQQQQQQQQQQQLNHVDGSSKAAVLAAPSGLERYGLSAAAAAAVEQRSRFEYPPPPVSLGSSSHAARLPNGLGGPNGFPKPNPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVAGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAPVLPPPPPHALGSRGPPTPAPPGAPGGPACLGGAPGVSVASSSAASSTSSSVAEVGVGAGGKRPGSVSSTDQERELKEKQRNAEALAELSESLRNRAEEWANKPKMVRDTLLTLAGCTPYEVRFKKDHSLLGRVFAFDAVSKPGMDYELKLFIEYPTGSGNVYSSASGVAKQMYQDCMKDFGRGLSSGFKYLEYEKKHGSGDWRLLGDLLPEAVRFFKEGVPGADMLPQPYLDASCPMLPTALVSLSRAPSAPPGTGALPPATPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLTSRNGDLNLQVAPPPPSTHPGMDQVHPQNIPDSPMANSGPLCCTICHERLEDTHFVQCPSVPSHKFCFPCSRESIKAQGATGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDP", "length": 774, "header": "tr|A0ABI0NYR9-1|A0ABI0NYR9_BOVIN Isoform 1 of Interferon regulatory factor 2 binding protein like OS=Bos taurus OX=9913 GN=IRF2BPL PE=3 SV=1 CANONICAL=A0ABI0NYR9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NYR9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYR9/entry#A0ABI0NYR9-1", "sequence": { "sequence": "MSAAQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRAHGCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAQQQQQQQQQQQQLNHVDGSSKAAVLAAPSGLERYGLSAAAAAAVEQRSRFEYPPPPVSLGSSSHAARLPNGLGGPNGFPKPNPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVAGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAPVLPPPPPHALGSRGPPTPAPPGAPGGPACLGGAPGVSVASSSAASSTSSSVAEVGVGAGGKRPGSVSSTDQERELKEKQRNAEALAELSESLRNRAEEWANKPKMVRDTLLTLAGCTPYEVRFKKDHSLLGRVFAFDAVSKPGMDYELKLFIEYPTGSGNVYSSASGVAKQMYQDCMKDFGRGLSSGFKYLEYEKKHGSGDWRLLGDLLPEAVRFFKEGVPGADMLPQPYLDASCPMLPTALVSLSRAPSAPPGTGALPPATPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLTSRNGDLNLQVAPPPPSTHPGMDQVHPQNIPDSPMANSGPLCCTICHERLEDTHFVQCPSVPSHKFCFPCSRESIKAQGATGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDP", "length": 774, "header": "tr|A0ABI0NYR9-1|A0ABI0NYR9_BOVIN Isoform 1 of Interferon 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[provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377123" }, "gene_names": [ { "name": "OR4C3", "type": "recommended", "evidence": [ { "id": "A0ABI0NYW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYW1" } ] }, { "name": "OR4C3", "type": "synonym", "evidence": [ { "id": "NP_001377123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377123" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NYW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYW1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 4 subfamily C member 3", "type": "synonym", "evidence": [ { "id": "NP_001377123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377123" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB18 is required for the localization of ZFYVE1 to lipid droplets and for its function in mediating the formation of endoplasmic reticulum-lipid droplets (ER-LD) contacts. Also required for maintaining endoplasmic reticulum structure. Plays a role in apical endocytosis/recycling. 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triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377140" }, "gene_names": [ { "name": "OR2AH1", "type": "recommended", "evidence": [ { "id": "A0ABI0NZ91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ91" } ] }, { "name": "OR2AH1", "type": "synonym", "evidence": [ { "id": "NP_001377140", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377140" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NZ91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ91/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 2G3", "type": "synonym", "evidence": [ { "id": "NP_001377140", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377140" } ] }, { "name": "olfactory receptor family 2 subfamily AH member 1", "type": "synonym", "evidence": [ { "id": "NP_001377140", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377140" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377140", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377140" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZ91", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ91#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZ91", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ91" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2AH1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ91", "locus": {} } ], "crossref": [ { "id": "cd15237", "url": 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[], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 66, "end_pos": 68 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Was also reported to mediate dimethylation of pre-miR-145; however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZ92", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ92#function" }, { "database": "UniProtKB", "id": "ARBA00045273", "url": "https://www.uniprot.org/uniprotkb/ARBA00045273#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZ92", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ92" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BCDIN3D", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ92", "locus": { "chromosome": "5", "start_pos": 30047717, "end_pos": 30041969, "strand": "-", "evidence": [ { "database": "Ensembl 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"categories": [ "Protein Classification" ] }, { "id": "PF06859", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06859", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "58640", "url": "https://www.rhea-db.org/rhea/58640", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "58656", "url": "https://www.rhea-db.org/rhea/58656", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NZ92", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ92-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMMPRGNANPLFPLSPMGGRLYTQSLCRSAQARWSPGGLKVQDFRFRGDSEARLRLMAASTEQATGGVEKTAAEEKPRVLEPGAAPFGNFPHYSRFHPPEQRLRLLPPELLRRLFPQSPETRPILGLDVGCNSGDLSVALYKHFLSLHDGETCLDASRELHLLCCDIDPVLVERAEKECPFPDGLTFITLDFMNQRTRKVLLSSFLSQFGRSVFDIGFCMSVTMWIHLNHGDQGLWEFLAHLSSLCRYLLVEPQPWKCYRAAARRLRKLGLHDFDHFRSLAIRGDMASQIVQILTQDHGMELVCCFGNTKWDRSLLLFRTKQATETHPIPESLIEEGKERNRIRFWRE", "length": 349, "header": "tr|A0ABI0NZ92-1|A0ABI0NZ92_BOVIN Isoform 1 of RNA methyltransferase OS=Bos taurus OX=9913 GN=BCDIN3D PE=3 SV=1 CANONICAL=A0ABI0NZ92-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NZ92-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ92/entry#A0ABI0NZ92-1", "sequence": { "sequence": 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ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12386", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12386", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04718", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04718", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NZB8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZB8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQFVRNLAEKAPALVNAAVTYSKPRLATFWYYAKVELVPPTPAEIPTAIQSLTKIINSAKTGSFKQLTVKEALLNGLVATEVWMWFYVGEIIGKRGIMGYDV", "length": 103, "header": "tr|A0ABI0NZB8-1|A0ABI0NZB8_BOVIN Isoform 1 of ATP synthase F(0) complex subunit g, mitochondrial OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NZB8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NZB8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZB8/entry#A0ABI0NZB8-1", "sequence": { "sequence": "MAQFVRNLAEKAPALVNAAVTYSKPRLATFWYYAKVELVPPTPAEIPTAIQSLTKIINSAKTGSFKQLTVKEALLNGLVATEVWMWFYVGEIIGKRGIMGYDV", "length": 103, "header": "tr|A0ABI0NZB8-1|A0ABI0NZB8_BOVIN Isoform 1 of ATP synthase F(0) complex subunit g, mitochondrial OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NZB8-1" }, "locus": { "chromosome": "3", "start_pos": 28514381, "end_pos": 28514073, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143210.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143210.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106982.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106982.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { 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"https://www.uniprot.org/uniprotkb/A0ABI0NZB8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "proton transmembrane transporter activity", "id": "GO:0015078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015078", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZB8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZB8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proton motive force-driven ATP synthesis", "id": "GO:0015986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015986", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZB8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 42 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { 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"https://www.uniprot.org/uniprotkb/A0ABI0NZC5", "locus": {} } ], "crossref": [ { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF56", "database": "PANTHER", "categories": [ "Protein 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"MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSSSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVRNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYKQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKTG", "length": 543, "header": "tr|A0ABI0NZC5-1|A0ABI0NZC5_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0NZC5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NZC5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZC5/entry#A0ABI0NZC5-1", "sequence": { "sequence": 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"ENSBTAP00000106560.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106560.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZC5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZC5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZC5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZC5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZC5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0NZC5", "database": "UniProtKB", "url": 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"MSVSALSPSRALGGVSGLLQVVSLLGLVLLLIKAAQLYLRRQWLLKALHHFPSPPSHWFYGHKREFQEEGELPHLLKRVEKYPRACVRWMWGTRALLLVYDPDYMKMVLGRSDPKAQIIHRFVKPWIGTGLLLLEGQTWFQHRRMLTPAFHYDILKPYVGIMADSVRVMLDKWEELVSQDSHLEIFGHVSLMTLDTIMKCAFSQQGSVQTDRNSQSYIQAIKDVSHLIISRLRNAFHQNDLIYRLTPEGHWNHRACQLAHQHTDAVIKERKVRLQKEGELEKVRSRRHLDFLDILLFARMENGSSLSDEDLRAEVDTFMFEGHDTTASGISWILYALASHPEHQQRCREEIQSLLADGASITWDHLDQMPYTTMCIKEAMRLYPPVPVISRELSKPITFPDGRSLPAGILVSLSIYGLHHNPKVWPNPEVFDPTRFAPGSTRHSHAFLPFSGGSRNCIGKQFAMNELKVAVALTLLRFELSPDSSRVPVPMPVIVLRSKNGIYLQLRKLSDPGT", "length": 514, "header": "tr|A0ABI0NZF4-1|A0ABI0NZF4_BOVIN Isoform 1 of Cytochrome P450 family 4 subfamily A member 59 OS=Bos taurus OX=9913 GN=CYP4A11 PE=3 SV=1 CANONICAL=A0ABI0NZF4-1" }, "locus": { "chromosome": "3", "start_pos": 99222157, "end_pos": 99208616, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154639.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154639.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107049.1", 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376886" }, "gene_names": [ { "name": "OR7E201", "type": "recommended", "evidence": [ { "id": "A0ABI0NZG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG2" } ] }, { "name": "OR7E201", "type": "synonym", "evidence": [ { "id": "NP_001376886", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376886" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 7 subfamily E member 201", "type": "synonym", "evidence": [ { "id": "A0ABI0NZG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 18", "type": "synonym", "evidence": [ { "id": "NP_001376886", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376886" } ] }, { "name": "olfactory receptor family 7 subfamily E member 201", "type": "synonym", "evidence": [ { "id": "NP_001376886", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376886" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376886", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376886" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZG2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZG2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR7E201", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZG2", "locus": {} } ], "crossref": [ { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514883", "url": "https://www.ncbi.nlm.nih.gov/gene/514883", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein 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"isoform_ac": "A0ABI0NZR0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZR0/entry#A0ABI0NZR0-1", "sequence": { "sequence": "MRPIQKEPEKVEVLQPEEHFEQFLFPVISEVQEAIVPRTGVHRKAYDIIGSGCRKWAINSSNKTQVESLGKSTLNYFQNQWSQGQSDQKVQEGGEGDSGHKIKEVFAKALERLGKESEDYLQWALTWTGNRYLQCSINHPTISSFE", "length": 146, "header": "tr|A0ABI0NZR0-1|A0ABI0NZR0_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0NZR0-1" }, "locus": { "chromosome": "6", "start_pos": 55750300, "end_pos": 55747978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152087.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152087.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106037.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106037.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0NZR5-1", "uniprot_ac": "A0ABI0NZR5", "uniprot_id": "A0ABI0NZR5_BOVIN", "mass": { "chemical_mass": 34327.0, "monoisotopic_mass": 34327.0 }, "refseq": { "ac": "NP_001376815", "name": "olfactory receptor family 7 subfamily E member 182", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376815" }, "gene_names": [ { "name": "OR7E182", "type": "recommended", "evidence": [ { "id": "A0ABI0NZR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZR5" } ] }, { "name": "OR7E182", "type": "synonym", "evidence": [ { "id": "NP_001376815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376815" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 7 subfamily E member 182", "type": "synonym", "evidence": [ { "id": "A0ABI0NZR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZR5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 18", "type": "synonym", "evidence": [ { "id": "NP_001376815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376815" } ] }, { "name": "olfactory receptor family 7 subfamily E member 182", "type": "synonym", "evidence": [ { "id": "NP_001376815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376815" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376815", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376815" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZR5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZR5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR7E182", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZR5", "locus": {} } ], "crossref": [ { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "511642", "url": "https://www.ncbi.nlm.nih.gov/gene/511642", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376815", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376815", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NZR5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZR5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZR5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPQNLTDVSEFLLLGLSDDPDMQPLLFGLFLSMYLVTVLGNLLIILAVSSNSHLHTPMYFFLSNLSLTDVSFSTTTIPKMLVNLQTHSKSITYAGCLTQLTFFSLFAFLESLLLTVMAYDRLVAICHPLHYLVIMNPRFCGLLVLVSFSISLLTSLLHCLMVSQLTFCEDVEVPHFFCELSQLLNLSCSDTFINNILIYFIGAILGGVPLSGIIYSYTQITSSILRVSSSYGKYKAFSTCGSHLSVVCLFYGTGLGVYLSSTVSSSHRKSAVVSVMYTVVTPMLNPFIYSLRNKDIKSTLWRIIIKKA", "length": 309, "header": "tr|A0ABI0NZR5-1|A0ABI0NZR5_BOVIN Isoform 1 of Olfactory receptor family 7 subfamily E member 182 OS=Bos taurus OX=9913 GN=OR7E182 PE=3 SV=1 CANONICAL=A0ABI0NZR5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NZR5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZR5/entry#A0ABI0NZR5-1", "sequence": { "sequence": "MKPQNLTDVSEFLLLGLSDDPDMQPLLFGLFLSMYLVTVLGNLLIILAVSSNSHLHTPMYFFLSNLSLTDVSFSTTTIPKMLVNLQTHSKSITYAGCLTQLTFFSLFAFLESLLLTVMAYDRLVAICHPLHYLVIMNPRFCGLLVLVSFSISLLTSLLHCLMVSQLTFCEDVEVPHFFCELSQLLNLSCSDTFINNILIYFIGAILGGVPLSGIIYSYTQITSSILRVSSSYGKYKAFSTCGSHLSVVCLFYGTGLGVYLSSTVSSSHRKSAVVSVMYTVVTPMLNPFIYSLRNKDIKSTLWRIIIKKA", "length": 309, "header": "tr|A0ABI0NZR5-1|A0ABI0NZR5_BOVIN Isoform 1 of Olfactory receptor family 7 subfamily E member 182 OS=Bos taurus OX=9913 GN=OR7E182 PE=3 SV=1 CANONICAL=A0ABI0NZR5-1" }, "locus": { "chromosome": "7", "start_pos": 13763691, "end_pos": 13762765, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136415.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136415.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106804.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106804.1" } ] } } ], "glycosylation": 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Monomethylates 'Lys-491' of CGAS, promoting interaction between SGF29 and CGAS.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0#function" }, { "database": "UniProtKB", "id": "ARBA00058230", "url": "https://www.uniprot.org/uniprotkb/ARBA00058230#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SETD7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0", "locus": { "chromosome": "17", "start_pos": 18208367, "end_pos": 18156231, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003581", "url": "https://www.ensembl.org/id/ENSBTAG00000003581" } ] } } ], "crossref": [ { "id": "cd10530", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10530", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46820", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46820", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46820:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46820:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "51736", "url": "https://www.rhea-db.org/rhea/51736", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { 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CANONICAL=A0ABI0NZS0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NZS0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0/entry#A0ABI0NZS0-1", "sequence": { "sequence": "MVPRRVGTQRARGSAPALAQPPRAPGGTRGSRAAPSWAGSPAAMDSDDEMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFIHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLLSTEEGRPHFELMPGSSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAAGPDTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCVYDMFVHPRFGPIKCIRTLRAVEANEELTVAYGYDHSPPGKSGPEAPEWYQVELKAFQATQQK", "length": 409, "header": "tr|A0ABI0NZS0-1|A0ABI0NZS0_BOVIN Isoform 1 of Histone-lysine N-methyltransferase SETD7 OS=Bos taurus OX=9913 GN=SETD7 PE=4 SV=1 CANONICAL=A0ABI0NZS0-1" }, "locus": { "chromosome": "17", "start_pos": 18207363, "end_pos": 18155335, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150961.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150961.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107256.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107256.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "histone H3K4 monomethyltransferase activity", "id": "GO:0140945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140945", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NZS0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "51736", "name": "", "equation": "L-lysyl-[protein] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2YDJ8-1", "Q0P585-1", "P0DPE2-1", "A4FV98-1", "E1BI64-1", "A5PK19-1", "A6QP81-1", "E1B906-1", "G3X834-1", "F1MDT8-1", "A0A3Q1MPX3-1", "A0AAA9SSU7-1", "A0ABI0NZS0-1" ], "evidence": [ { "id": "51736", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51736" } ] }, { "id": "60264", "name": "", "equation": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TQW6-1", "E1B9N8-1", "F1MHA1-1", "E1BKN0-1", "E1B906-1", "F1N6Y5-1", "E1BLX2-1", "A0ABI0NZS0-1" ], "evidence": [ { "id": "60264", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60264" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MPX3", "gene_name": "PRDM9", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.355", "activity": "L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.355", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "A0A3Q1MPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPX3" } ] } ] }, { "uniprot_ac": "A0AAA9SSU7", "gene_name": "", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.355", "activity": "L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.355", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "A0AAA9SSU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSU7" } ] } ] }, { "uniprot_ac": "A0AAA9TQW6", "gene_name": "KMT2C", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0AAA9TQW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQW6" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "A0AAA9TQW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQW6" } ] } ] }, { "uniprot_ac": "A0ABI0NZS0", "gene_name": "SETD7", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0ABI0NZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "A0ABI0NZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZS0" } ] } ] }, { "uniprot_ac": "A4FV98", "gene_name": "EEF1AKMT3", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A4FV98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FV98" } ] } ] }, { "uniprot_ac": "A5PK19", "gene_name": "METTL13", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A5PK19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PK19" } ] } ] }, { "uniprot_ac": "A6QP81", "gene_name": "METTL21C", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A6QP81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QP81" } ] } ] }, { "uniprot_ac": "E1B906", "gene_name": "SETD4", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1B906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "E1B906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B906" } ] } ] }, { "uniprot_ac": "E1B9N8", "gene_name": "KMT2D", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1B9N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N8" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "E1B9N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N8" } ] } ] }, { "uniprot_ac": "E1BI64", "gene_name": "SETD6", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "E1BI64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI64" } ] } ] }, { "uniprot_ac": "E1BKN0", "gene_name": "KMT2B", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1BKN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKN0" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "E1BKN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKN0" } ] } ] }, { "uniprot_ac": "E1BLX2", "gene_name": "SETD1A", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "E1BLX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "E1BLX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLX2" } ] } ] }, { "uniprot_ac": "F1MDT8", "gene_name": "SETD2", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "F1MDT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDT8" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "F1MDT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDT8" } ] } ] }, { "uniprot_ac": "F1MHA1", "gene_name": "KMT2A", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "F1MHA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHA1" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "F1MHA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHA1" } ] } ] }, { "uniprot_ac": "F1N6Y5", "gene_name": "SETD1B", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "F1N6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6Y5" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "F1N6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6Y5" } ] } ] }, { "uniprot_ac": "G3X834", "gene_name": "", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", 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[provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377286" }, "gene_names": [ { "name": "OR51L15", "type": "recommended", "evidence": [ { "id": "A0ABI0NZU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZU2" } ] }, { "name": "OR51L15", "type": "synonym", "evidence": [ { "id": "NP_001377286", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377286" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0NZU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZU2/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 51 subfamily L member 15", "type": "synonym", "evidence": [ { "id": "NP_001377286", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377286" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376918" }, "gene_names": [ { "name": "OR51V1B", "type": "recommended", "evidence": [ { "id": "A0ABI0P029", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P029" } ] }, { "name": "OR51V1B", "type": "synonym", "evidence": [ { "id": "NP_001376918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376918" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0P029", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P029/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 51V1", "type": "synonym", "evidence": [ { "id": "NP_001376918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376918" } ] }, { "name": "olfactory receptor family 51 subfamily V member 1B", "type": "synonym", "evidence": [ { "id": "NP_001376918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376918" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376918", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376918" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P029", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P029#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P029", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P029" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR51V1B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P029", "locus": {} } ], "crossref": [ { "id": "cd15222", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15222", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "516414", "url": "https://www.ncbi.nlm.nih.gov/gene/516414", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376918", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376918", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0P029", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P029", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P029-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P029-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P060", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P060" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P060", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P060" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": 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"pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P093" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 305, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P283-1", "uniprot_ac": "A0ABI0P283", "uniprot_id": "A0ABI0P283_BOVIN", "mass": { "chemical_mass": 124737.0, "monoisotopic_mass": 124737.0 }, "refseq": {}, "gene_names": [ { "name": "ADCY3", "type": "recommended", "evidence": [ { "id": "A0ABI0P283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283" } ] } ], "protein_names": [ { "name": "Adenylate cyclase type 3", "type": "recommended", "evidence": [ { "id": "A0ABI0P283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283/entry#names_and_taxonomy" } ] }, { "name": "4.6.1.1", "type": "synonym", "evidence": [ { "id": "A0ABI0P283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.", "evidence": [ { "database": "UniProtKB", "id": "F1MPC9", "url": "https://www.uniprot.org/uniprotkb/F1MPC9#function" }, { "database": "UniProtKB", "id": "PIRNR039050", "url": "https://www.uniprot.org/uniprotkb/PIRNR039050#function" }, { "database": "UniProtKB", "id": "A0ABI0NXU2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXU2#function" }, { "database": "UniProtKB", "id": "A0ABI0P283", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P283", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ADCY3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283", "locus": { "chromosome": "11", "start_pos": 74418321, "end_pos": 74334959, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018705", "url": "https://www.ensembl.org/id/ENSBTAG00000018705" } ] } } ], "crossref": [ { "id": "ENSBTAG00000018705", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018705", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07302", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07302", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "535603", "url": "https://www.ncbi.nlm.nih.gov/gene/535603", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018297", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018297", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MPC9", "url": "https://www.orthodb.org/?gene=F1MPC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45627", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45627", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45627:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45627:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00211", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00211", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-163615", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163615", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-170660", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170660", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-170670", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170670", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-418597", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5610787", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5610787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "15389", "url": "https://www.rhea-db.org/rhea/15389", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NXU2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXU2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P283", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P283-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MPC9", "url": "https://www.uniprot.org/uniprotkb/F1MPC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MPC9-1", "url": "https://www.uniprot.org/uniprotkb/F1MPC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRTQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPESLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSGDKLAPLAVAGVGLVLDIILFVLCKKGLLPNRVTRRVVPYLLWLLISAQVFSYLGLNFSRAHAASDTVGWQAFFVFSFFITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDGLKGVQLLREILANVFLYLCAIVVGIMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGEGGSRCDYLEEKGIETYLIIASKPEVKKTAAQNGLNGSALLNGAPPSSKPSSPALIETKESNGSIHTSGSVSEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESAQVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTAVVEILIDPWLMTNYVTFVVGEALLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMANVVDMLSCLQYYTGPTNGTAEMQVEDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLMLLIAGAVAVINIYAWCPIFDDYDRKRFQQHDFPMVALEKMQVFSSSGLNGTDRLPLVPSKYSMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKDEKSDKERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQVRPGDRIRTVHVLLGTVACSVGPEC", "length": 1110, "header": "tr|A0ABI0P283-1|A0ABI0P283_BOVIN Isoform 1 of Adenylate cyclase type 3 OS=Bos taurus OX=9913 GN=ADCY3 PE=3 SV=1 CANONICAL=A0ABI0P283-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NXU2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283/entry#A0ABI0NXU2-1", "sequence": { "sequence": "MRLTFVPESLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSGDKLAPLAVAGVGLVLDIILFVLCKKGLLPNRVTRRVVPYLLWLLISAQVFSYLGLNFSRAHAASDTVGWQAFFVFSFFITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDGLKGVQLLREILANVFLYLCAIVVGIMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGEGGSRCDYLEEKGIETYLIIASKPEVKKTAAQNGLNGSALLNGAPPSSKPSSPALIETKESNGSIHTSGSVSEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESAQVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTAVVEILIDPWLMTNYVTFVVGEALLLILTICSLAAIFPRLSCLQYYTGPTNGTAEMQVEDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLMLLIAGAVAVINIYAWCPIFDDYDRKRFQQHDFPMVALEKMQVFSSSGLNGTDRLPLVPSKYSMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKDEKSDKERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKLATFPNGASITLPHQVVDNS", "length": 1054, "header": "tr|A0ABI0NXU2-1|A0ABI0P283_BOVIN Computationally mapped isoform of Adenylate cyclase type 3 OS=Bos taurus OX=9913 GN=ADCY3 PE=3 SV=1 CANONICAL=A0ABI0P283-1" }, "locus": { "chromosome": "11", "start_pos": 74418091, "end_pos": 74335789, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150188.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150188.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104629.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104629.1" } ] } }, { "isoform_ac": "A0ABI0P283-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283/entry#A0ABI0P283-1", "sequence": { "sequence": "MPRTQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPESLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSGDKLAPLAVAGVGLVLDIILFVLCKKGLLPNRVTRRVVPYLLWLLISAQVFSYLGLNFSRAHAASDTVGWQAFFVFSFFITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDGLKGVQLLREILANVFLYLCAIVVGIMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGEGGSRCDYLEEKGIETYLIIASKPEVKKTAAQNGLNGSALLNGAPPSSKPSSPALIETKESNGSIHTSGSVSEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESAQVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTAVVEILIDPWLMTNYVTFVVGEALLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMANVVDMLSCLQYYTGPTNGTAEMQVEDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLMLLIAGAVAVINIYAWCPIFDDYDRKRFQQHDFPMVALEKMQVFSSSGLNGTDRLPLVPSKYSMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKDEKSDKERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQVRPGDRIRTVHVLLGTVACSVGPEC", "length": 1110, "header": "tr|A0ABI0P283-1|A0ABI0P283_BOVIN Isoform 1 of Adenylate cyclase type 3 OS=Bos taurus OX=9913 GN=ADCY3 PE=3 SV=1 CANONICAL=A0ABI0P283-1" }, "locus": { "chromosome": "11", "start_pos": 74417422, "end_pos": 74335633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153237.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153237.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106890.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106890.1" } ] } }, { "isoform_ac": "F1MPC9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283/entry#F1MPC9-1", "sequence": { "sequence": "MPRTQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPESLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSGDKLAPLAVAGVGLVLDIILFVLCKKGLLPNRVTRRVVPYLLWLLISAQVFSYLGLNFSRAHAASDTVGWQAFFVFSFFITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDGLKGVQLLREENLMLSILPKHVADEMLKDMKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGEGGSRCDYLEEKGIETYLIIASKPEVKKTAAQNGLNGSALLNGAPPSSKPSSPALIETKESNGSIHTSGSVSEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESAQVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTAVVEILIDPWLMTNYVTFVVGEALLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMANVVDMLSCLQYYTGPTNGTAEMQVEDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLMLLIAGAVAVINIYAWCPIFDDYDRKRFQQHDFPMVALEKMQVFSSSGLNGTDRLPLVPSKYSMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKDEKSDKERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKLATFPNGASITLPHQVVDNS", "length": 1095, "header": "tr|F1MPC9-1|A0ABI0P283_BOVIN Computationally mapped isoform of Adenylate cyclase type 3 OS=Bos taurus OX=9913 GN=ADCY3 PE=3 SV=4 CANONICAL=A0ABI0P283-1" }, "locus": { "chromosome": "11", "start_pos": 74418091, "end_pos": 74335633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032950.6", "url": "https://www.ensembl.org/id/ENSBTAT00000032950.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032877.6", "url": "https://www.ensembl.org/id/ENSBTAP00000032877.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-163615", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163615", "resource": "Reactome", "description": "PKA activation" }, { "id": "R-BTA-170660", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170660", "resource": "Reactome", "description": "Adenylate cyclase activating pathway" }, { "id": "R-BTA-170670", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170670", "resource": "Reactome", "description": "Adenylate cyclase inhibitory pathway" }, { "id": "R-BTA-418597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418597", "resource": "Reactome", "description": "G alpha (z) signalling events" }, { "id": "R-BTA-5610787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5610787", "resource": "Reactome", "description": "Hedgehog 'off' state" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "adenylate cyclase activity", "id": "GO:0004016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004016", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P283", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P283", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P283", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P283", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cAMP biosynthetic process", "id": "GO:0006171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006171", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P283", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P283", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P283", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P283" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1033, "end_pos": 1035, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 509, "end_pos": 511, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 736, "end_pos": 738, "annotation": "n_glycosylation_sequon" }, { "start_pos": 829, "end_pos": 831, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15389", "name": "", "equation": "ATP = 3',5'-cyclic AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TFX0-1", "A0A3Q1MA58-1", "E1B9K3-1", "E1BQ12-1", "E1BHU9-1", "A0ABI0P283-1", "P19754-1", "A0ABI0P529-1", "Q29450-1", "E1BM79-1", "A0AAA9U028-1" ], "evidence": [ { "id": "15389", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15389" } ] }, { "id": "R-BTA-111930", "name": "Adenylate cyclase produces cAMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19754-1", "E1BHU9-1", "A0ABI0P283-1", "A0AAA9TFX0-1", "E1B9K3-1", "E1BM79-1", "E1BQ12-1", "A0A3Q1MA58-1" ], "evidence": [ { "id": "R-BTA-111930", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111930" } ] }, { "id": "R-BTA-170666", "name": "Adenylate cyclase increases the GTPase activity of G alpha-olf", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19754-1", "E1BHU9-1", "A0ABI0P283-1", "A0AAA9TFX0-1", "P63097-1", "E1B9K3-1", "E1BM79-1", "E1BQ12-1", "A0A3Q1MA58-1" ], "evidence": [ { "id": "R-BTA-170666", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170666" } ] }, { "id": "R-BTA-170671", "name": "G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19754-1", "E1BHU9-1", "A0ABI0P283-1", "A0AAA9TFX0-1", "P63097-1", "E1B9K3-1", "E1BM79-1", "E1BQ12-1", "A0A3Q1MA58-1" ], "evidence": [ { "id": "R-BTA-170671", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170671" } ] }, { "id": "R-BTA-170672", "name": "Galpha-olf:GTP binds to adenylate cyclase and activates it", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19754-1", "E1BHU9-1", "A0ABI0P283-1", "A0AAA9TFX0-1", "E1B9K3-1", "E1BM79-1", "E1BQ12-1", "A0A3Q1MA58-1" ], "evidence": [ { "id": "R-BTA-170672", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170672" } ] }, { "id": "R-BTA-170674", "name": "Dissociation of the Gi alpha:G olf complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19754-1", "E1BHU9-1", "A0ABI0P283-1", "A0AAA9TFX0-1", "P63097-1", "E1B9K3-1", "E1BM79-1", "E1BQ12-1", "A0A3Q1MA58-1" ], "evidence": [ { "id": "R-BTA-170674", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170674" } ] }, { "id": "R-BTA-170676", "name": "Adenylate cyclase converts ATP into cyclic AMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19754-1", "E1BHU9-1", "A0ABI0P283-1", "A0AAA9TFX0-1", "E1B9K3-1", "E1BM79-1", "E1BQ12-1", "A0A3Q1MA58-1" ], "evidence": [ { "id": "R-BTA-170676", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170676" } ] }, { "id": "R-BTA-170677", "name": "The G alpha-olf:GDP:Adenylate cyclase complex dissociates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19754-1", "E1BHU9-1", "A0ABI0P283-1", "A0AAA9TFX0-1", "E1B9K3-1", "E1BM79-1", "E1BQ12-1", "A0A3Q1MA58-1" ], "evidence": [ { "id": "R-BTA-170677", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170677" } ] }, { "id": "R-BTA-170685", "name": "Adenylaye cyclase increases the GTPase activity of G alpha-olf", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19754-1", "E1BHU9-1", "A0ABI0P283-1", "A0AAA9TFX0-1", "E1B9K3-1", "E1BM79-1", "E1BQ12-1", "A0A3Q1MA58-1" ], "evidence": [ { "id": "R-BTA-170685", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170685" } ] }, { "id": "R-BTA-170686", "name": "Adenylate cyclase increases the GTPase activity of Gi alpha", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19754-1", "E1BHU9-1", "A0ABI0P283-1", "A0AAA9TFX0-1", "P63097-1", "E1B9K3-1", "E1BM79-1", "E1BQ12-1", "A0A3Q1MA58-1" ], "evidence": [ { "id": "R-BTA-170686", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170686" } ] }, { "id": "R-BTA-392064", "name": "G alpha (z) inhibits adenylate cyclase", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19754-1", "E1BHU9-1", "A0ABI0P283-1", "A0AAA9TFX0-1", "E1B9K3-1", "E1BM79-1", "E1BQ12-1", "A0A3Q1MA58-1" ], "evidence": [ { "id": "R-BTA-392064", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-392064" } ] }, { "id": "R-BTA-5610727", "name": "GPR161 promotes cAMP production in a G alpha(s)-dependent manner", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19754-1", "E1BHU9-1", "A0ABI0P283-1", "A0AAA9TFX0-1", "E1B9K3-1", "E1BM79-1", "E1BQ12-1", "A0A3Q1MA58-1" ], "evidence": [ { "id": "R-BTA-5610727", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5610727" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MA58", "gene_name": "ADCY4", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0A3Q1MA58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA58" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0A3Q1MA58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA58" } ] } ] }, { "uniprot_ac": "A0AAA9TFX0", "gene_name": "ADCY2", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0AAA9TFX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFX0" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0AAA9TFX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFX0" } ] } ] }, { "uniprot_ac": "A0AAA9U028", "gene_name": "ADCY10", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0AAA9U028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U028" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0AAA9U028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U028" } ] } ] }, { "uniprot_ac": "A0ABI0P283", "gene_name": "ADCY3", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0ABI0P283", "database": "UniProtKB", 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"https://www.orthodb.org/?gene=E1BPN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45864", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45864", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45864:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45864:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08766", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08766", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23040", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23040", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005220202", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220202", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1N2B0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N2B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N2B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N2B0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1A3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1A3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1V4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1V4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P606", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P606", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P606-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P606-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BPN5", "url": "https://www.uniprot.org/uniprotkb/E1BPN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BPN5-1", "url": "https://www.uniprot.org/uniprotkb/E1BPN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALVTVQRSPTPSTTSSPCASSSHLEDSESAALLCCECEDSEIFSDSNEADSGEEECRSQPRSISESFLTVKGAALFLPRGNGSSTPRVSHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARMHNYYPGSLFLTWVSYYESHINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTRLREIMMQKDLENITSKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEPICKPGLELNKKEITTSADQIAEVKTMESHPPIPPVFVEHVVPQDENQKALCTKERMICLEFTSQEFHAGQIEDELNLNDINGCSSGCCLNEPKFPLDNCHASKALIQPGKDPEMAHKFPDLTVEDLETDALKADMNVHLLPMEELTSRLKDLPMSPDPESPSPQPSCQATVSDFSGDRIDFFSALEKFVELSQETRSRSFSHSRMEEVGGGRNESCRLSVVEAAPSEATTDDQRSSSLSNTPHASEESSVDEEQSKAISEQVSPDIFMQPHSENAMSVKEIVTEIESISQGVGQIQVKGDVLSNPCHTPKKHIVHELPLERAQAAENRPGNLEQSEGSCPAQPEPAKDSGKGDPEGCPGAHSSTAEVEEEEPVEGEQELWGPGMPPGAKWYPGSVRRATLEFEERLRQEQEHHGAAPAGTSLSTRKNSKNDSSVADLAAKGKSDEAAPELSYVPKEPETGRGQGRCGGSESGSLLRPEQLAIVPAPELRESHPAPATQDGPRHEGILREPRTVVSGQGPETPAAPAAFPKKIEIIEYTYTATSPDPGPGWERASSEKSGAQGLRTVKVEETLTVLCALDENLNRTLSPDQAPLHPRVLPPPHSSSPQHEHSRPVDLPPTLSSPAAPIVSPTTQPCGASPDHLHPQTVVHLEGFTGQSSTTDSEPSTEQGSWEESQEGPLSRASEVPYQGSQFSSEDLHLISQLGNNIGEQPEKLDPTSVAHQLPHSSSSDSIESPSQSPRVVKGRAKEIESRATSQVGLPKPPQLRRSASLAKLGYLDLCKDCSPEREPVSSESPHLKLLQPFLRTDSGMEAQEPPENPDTPQNREPTKYLIEQLRTTECIAQSRPVERPLAQYAKEFGSSQQCLLPRAGPGLTSSEGGLPSVPTQGLQDTSPAPGLAVAPREQHGRTHPLRRLRKANDKKRTTNPFYNTM", "length": 1429, "header": "tr|A0ABI0P1A3-1|A0ABI0P1A3_BOVIN Isoform 1 of protein-serine/threonine phosphatase OS=Bos taurus OX=9913 GN=SSH2 PE=3 SV=1 CANONICAL=A0ABI0P1A3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N2B0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3/entry#A0A3Q1N2B0-1", "sequence": { "sequence": "MNISESFLTVKGAALFLPRGNGSSTPRVSHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARMHNYYPGSLFLTWVSYYESHINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTRLREIMMQKDLENITSKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEPICKPGLELNKKEITTSADQIAEVKTMESHPPIPPVFVEHVVPQDENQKALCTKERMICLEFTSQEFHAGQIEDELNLNDINGCSSGCCLNEPKFPLDNCHASKALIQPGKDPEMAHKFPDLTVEDLETDALKADMNVHLLPMEELTSRLKDLPMSPDPESPSPQPSCQATVSDFSGDRIDFFSALEKFVELSQETRSRSFSHSRMEEVGGGRNESCRLSVVEAAPSEATTDDQRSSSLSNTPHASEESSVDEEQSKAISEQVSPDIFMQPHSENAMSVKEIVTEIESISQGVGQIQVKGDVLSNPCHTPKKHIVHELPLERAQAAENRPGNLEQSEGSCPAQPEPAKDSGKGDPEGCPGAHSSTAEVEEEEPVEGEQELWGPGMPPGAKWYPGSVRRATLEFEERLRQEQEHHGAAPAGTSLSTRKNSKNDSSVADLAAKGKSDEAAPELSYVPKEPETGRGQGRCGGSESGSLLRPEQLAIVPAPELRESHPAPATQDGPRHEGILREPRTVVSGQGPETPAAPAAFPKKIEIIEYTYTATSPDPGPGWERASSEKSGAQGLRTVKVEETLTVLCALDENLNRTLSPDQAPLHPRVLPPPHSSSPQHEHSRPVDLPPTLSSPAAPIVSPTTQPCGASPDHLHPQTVVHLEGFTGQSSTTDSEPSTEQGSWEESQEGPLSRASEVPYQGSQFSSEDLHLISQLGNNIGEQPEKLDPTSVAHQLPHSSSSDSIESPSQSPRVVKGRAKEIESRATSQVGLPKPPQLRRSASLAKLGYLDLCKDCSPEREPVSSESPHLKLLQPFLRTDSGMEAQEPPENPDTPQNREPTKYLIEQLRTTECIAQSRPVERPLAQYAKEFGSSQQCLLPRAGPGLTSSEGGLPSVPTQGLQDTSPAPGLAVAPREQHGRTHPLRRLRKANDKKRTTNPFYNTM", "length": 1368, "header": "tr|A0A3Q1N2B0-1|A0ABI0P1A3_BOVIN Computationally mapped isoform of protein-serine/threonine phosphatase OS=Bos taurus OX=9913 GN=SSH2 PE=3 SV=2 CANONICAL=A0ABI0P1A3-1" }, "locus": { "chromosome": "19", "start_pos": 20976938, "end_pos": 20882418, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077654.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077654.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063364.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063364.2" } ] } }, { "isoform_ac": "A0ABI0P1A3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3/entry#A0ABI0P1A3-1", "sequence": { "sequence": "MALVTVQRSPTPSTTSSPCASSSHLEDSESAALLCCECEDSEIFSDSNEADSGEEECRSQPRSISESFLTVKGAALFLPRGNGSSTPRVSHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARMHNYYPGSLFLTWVSYYESHINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTRLREIMMQKDLENITSKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEPICKPGLELNKKEITTSADQIAEVKTMESHPPIPPVFVEHVVPQDENQKALCTKERMICLEFTSQEFHAGQIEDELNLNDINGCSSGCCLNEPKFPLDNCHASKALIQPGKDPEMAHKFPDLTVEDLETDALKADMNVHLLPMEELTSRLKDLPMSPDPESPSPQPSCQATVSDFSGDRIDFFSALEKFVELSQETRSRSFSHSRMEEVGGGRNESCRLSVVEAAPSEATTDDQRSSSLSNTPHASEESSVDEEQSKAISEQVSPDIFMQPHSENAMSVKEIVTEIESISQGVGQIQVKGDVLSNPCHTPKKHIVHELPLERAQAAENRPGNLEQSEGSCPAQPEPAKDSGKGDPEGCPGAHSSTAEVEEEEPVEGEQELWGPGMPPGAKWYPGSVRRATLEFEERLRQEQEHHGAAPAGTSLSTRKNSKNDSSVADLAAKGKSDEAAPELSYVPKEPETGRGQGRCGGSESGSLLRPEQLAIVPAPELRESHPAPATQDGPRHEGILREPRTVVSGQGPETPAAPAAFPKKIEIIEYTYTATSPDPGPGWERASSEKSGAQGLRTVKVEETLTVLCALDENLNRTLSPDQAPLHPRVLPPPHSSSPQHEHSRPVDLPPTLSSPAAPIVSPTTQPCGASPDHLHPQTVVHLEGFTGQSSTTDSEPSTEQGSWEESQEGPLSRASEVPYQGSQFSSEDLHLISQLGNNIGEQPEKLDPTSVAHQLPHSSSSDSIESPSQSPRVVKGRAKEIESRATSQVGLPKPPQLRRSASLAKLGYLDLCKDCSPEREPVSSESPHLKLLQPFLRTDSGMEAQEPPENPDTPQNREPTKYLIEQLRTTECIAQSRPVERPLAQYAKEFGSSQQCLLPRAGPGLTSSEGGLPSVPTQGLQDTSPAPGLAVAPREQHGRTHPLRRLRKANDKKRTTNPFYNTM", "length": 1429, "header": "tr|A0ABI0P1A3-1|A0ABI0P1A3_BOVIN Isoform 1 of protein-serine/threonine phosphatase OS=Bos taurus OX=9913 GN=SSH2 PE=3 SV=1 CANONICAL=A0ABI0P1A3-1" }, "locus": { "chromosome": "19", "start_pos": 21123875, "end_pos": 20882418, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144428.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144428.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105195.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105195.1" } ] } }, { "isoform_ac": "A0ABI0P1V4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3/entry#A0ABI0P1V4-1", "sequence": { "sequence": "MSSHLEDSESAALLCCECEDSEIFSDSNEADSGEEECRSQPRSISESFLTVKGAALFLPRGNGSSTPRVSHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARMHNYYPGSLFLTWVSYYESHINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTRLREIMMQKDLENITSKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEPICKPGLELNKKEITTSADQIAEVKTMESHPPIPPVFVEHVVPQDENQKALCTKERMICLEFTSQEFHAGQIEDELNLNDINGCSSGCCLNEPKFPLDNCHASKALIQPGKDPEMAHKFPDLTVEDLETDALKADMNVHLLPMEELTSRLKDLPMSPDPESPSPQPSCQATVSDFSGDRIDFFSALEKFVELSQETRSRSFSHSRMEEVGGGRNESCRLSVVEAAPSEATTDDQRSSSLSNTPHASEESSVDEEQSKAISEQVSPDIFMQPHSENAMSVKEIVTEIESISQGVGQIQVKGDVLSNPCHTPKKHIVHELPLERAQAAENRPGNLEQSEGSCPAQPEPAKDSGKGDPEGCPGAHSSTAEVEEEEPVEGEQELWGPGMPPGAKWYPGSVRRATLEFEERLRQEQEHHGAAPAGTSLSTRKNSKNDSSVADLAAKGKSDEAAPELSYVPKEPETGRGQGRCGGSESGSLLRPEQLAIVPAPELRESHPAPATQDGPRHEGILREPRTVVSGQGPETPAAPAAFPKKIEIIEYTYTATSPDPGPGWERASSEKSGAQGLRTVKVEETLTVLCALDENLNRTLSPDQAPLHPRVLPPPHSSSPQHEHSRPVDLPPTLSSPAAPIVSPTTQPCGASPDHLHPQTVVHLEGFTGQSSTTDSEPSTEQGSWEESQEGPLSRASEVPYQGSQFSSEDLHLISQLGNNIGEQPEKLDPTSVAHQLPHSSSSDSIESPSQSPRVVKGRAKEIESRATSQVGLPKPPQLRRSASLAKLGYLDLCKDCSPEREPVSSESPHLKLLQPFLRTDSGMEAQEPPENPDTPQNREPTKYLIEQLRTTECIAQSRPVERPLAQYAKEFGSSQQCLLPRAGPGLTSSEGGLPSVPTQGLQDTSPAPGLAVAPREQHGRTHPLRRLRKANDKKRTTNPFYNTM", "length": 1409, "header": "tr|A0ABI0P1V4-1|A0ABI0P1V4_BOVIN Computationally mapped isoform of protein-serine/threonine phosphatase OS=Bos taurus OX=9913 GN=SSH2 PE=3 SV=1 CANONICAL=A0ABI0P1A3-1" }, "locus": { "chromosome": "19", "start_pos": 21117861, "end_pos": 20882418, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154646.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154646.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104718.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104718.1" } ] } }, { "isoform_ac": "A0ABI0P606-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3/entry#A0ABI0P606-1", "sequence": { "sequence": "MALVTVQRSPTPSTTSSPCASEADSGEEECRSQPRSISESFLTVKGAALFLPRGNGSSTPRVSHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARMHNYYPGSLFLTWVSYYESHINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTRLREIMMQKDLENITSKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEPICKPGLELNKKEITTSADQIAEVKTMESHPPIPPVFVEHVVPQDENQKALCTKERMICLEFTSQEFHAGQIEDELNLNDINGCSSGCCLNEPKFPLDNCHASKALIQPGKDPEMAHKFPDLTVEDLETDALKADMNVHLLPMEELTSRLKDLPMSPDPESPSPQPSCQATVSDFSGDRIDFFSALEKFVELSQETRSRSFSHSRMEEVGGGRNESCRLSVVEAAPSEATTDDQRSSSLSNTPHASEESSVDEEQSKAISEQVSPDIFMQPHSENAMSVKEIVTEIESISQGVGQIQVKGDVLSNPCHTPKKHIVHELPLERAQAAENRPGNLEQSEGSCPAQPEPAKDSGKGDPEGCPGAHSSTAEVEEEEPVEGEQELWGPGMPPGAKWYPGSVRRATLEFEERLRQEQEHHGAAPAGTSLSTRKNSKNDSSVADLAAKGKSDEAAPELSYVPKEPETGRGQGRCGGSESGSLLRPEQLAIVPAPELRESHPAPATQDGPRHEGILREPRTVVSGQGPETPAAPAAFPKKIEIIEYTYTATSPDPGPGWERASSEKSGAQGLRTVKVEETLTVLCALDENLNRTLSPDQAPLHPRVLPPPHSSSPQHEHSRPVDLPPTLSSPAAPIVSPTTQPCGASPDHLHPQTVVHLEGFTGQSSTTDSEPSTEQGSWEESQEGPLSRASEVPYQGSQFSSEDLHLISQLGNNIGEQPEKLDPTSVAHQLPHSSSSDSIESPSQSPRVVKGRAKEIESRATSQVGLPKPPQLRRSASLAKLGYLDLCKDCSPEREPVSSESPHLKLLQPFLRTDSGMEAQEPPENPDTPQNREPTKYLIEQLRTTECIAQSRPVERPLAQYAKEFGSSQQCLLPRAGPGLTSSEGGLPSVPTQGLQDTSPAPGLAVAPREQHGRTHPLRRLRKANDKKRTTNPFYNTM", "length": 1402, "header": "tr|A0ABI0P606-1|A0ABI0P606_BOVIN Computationally mapped isoform of protein-serine/threonine phosphatase OS=Bos taurus OX=9913 GN=SSH2 PE=3 SV=1 CANONICAL=A0ABI0P1A3-1" }, "locus": { "chromosome": "19", "start_pos": 21123875, "end_pos": 20882418, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139439.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139439.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106820.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106820.1" } ] } }, { "isoform_ac": "E1BPN5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3/entry#E1BPN5-1", "sequence": { "sequence": "MTLSTLAREKKAPLACTCSLGGPDMIPYFSANAVISQNAINQLISESFLTVKGAALFLPRGNGSSTPRVSHRRNKHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQDTEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVHIFKPVSVQAMWSALQSLHKACEVARMHNYYPGSLFLTWVSYYESHINSDQSSVNEWNAMQDVQSHRPDSPALFTDIPTERERTERLIKTRLREIMMQKDLENITSKEIRTELEMQMVCNLREFKEFIDNEMIVILGQMDSPTQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPSFMRQLEEYQGILLASKQRHNKLWRSHSDSDLSDHHEPICKPGLELNKKEITTSADQIAEVKTMESHPPIPPVFVEHVVPQDENQKALCTKERMICLEFTSQEFHAGQIEDELNLNDINGCSSGCCLNEPKFPLDNCHASKALIQPGKDPEMAHKFPDLTVEDLETDALKADMNVHLLPMEELTSRLKDLPMSPDPESPSPQPSCQATVSDFSGDRIDFFSALEKFVELSQETRSRSFSHSRMEEVGGGRNESCRLSVVEAAPSEATTDDQRSSSLSNTPHASEESSVDEEQSKAISEQVSPDIFMQPHSENAMSVKEIVTEIESISQGVGQIQVKGDVLSNPCHTPKKHIVHELPLERAQAAENRPGNLEQSEGSCPAQPEPAKDSGKGDPEGCPGAHSSTAEVEEEEPVEGEQELWGPGMPPGAKWYPGSVRRATLEFEERLRQEQEHHGAAPAGTSLSTRKNSKNDSSVADLAAKGKSDEAAPELSYVPKEPETGRGQGRCGGSESGSLLRPEQLAIVPAPELRESHPAPATQDGPRHEGILREPRTVVSGQGPETPAAPAAFPKKIEIIEYTYTATSPDPGPGWERASSEKSGAQGLRTVKVEETLTVLCALDENLNRTLSPDQAPLHPRVLPPPHSSSPQHEHSRPVDLPPTLSSPAAPIVSPTTQPCGASPDHLHPQTVVHLEGFTGQSSTTDSEPSTEQGSWEESQEGPLSRASEVPYQGSQFSSEDLHLISQLGNNIGEQPEKLDPTSVAHQLPHSSSSDSIESPSQSPRVVKGRAKEIESRATSQVGLPKPPQLRRSASLAKLGYLDLCKDCSPEREPVSSESPHLKLLQPFLRTDSGMEAQEPPENPDTPQNREPTKYLIEQLRTTECIAQSRPVERPLAQYAKEFGSSQQCLLPRAGPGLTSSEGGLPSVPTQGLQDTSPAPGLAVAPREQHGRTHPLRRLRKANDKKRTTNPFYNTM", "length": 1409, "header": "tr|E1BPN5-1|A0ABI0P1A3_BOVIN Computationally mapped isoform of protein-serine/threonine phosphatase OS=Bos taurus OX=9913 GN=SSH2 PE=3 SV=3 CANONICAL=A0ABI0P1A3-1" }, "locus": { "chromosome": "19", "start_pos": 20980569, "end_pos": 20882418, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014625.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014625.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014625.6", "url": "https://www.ensembl.org/id/ENSBTAP00000014625.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 11, "start_aa": "Thr", "end_pos": 11, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr11", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1A3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1A3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1A3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of actin filament polymerization", "id": "GO:0030837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030837", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1A3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1081, "end_pos": 1083, "annotation": "n_glycosylation_sequon" }, { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 711, "end_pos": 713, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" }, { "start_pos": 928, "end_pos": 930, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAF6DLF7-1", "F1MI92-1", "A0A3Q1MV48-1", "E1BEW5-1", "F1ME76-1", "E1BAB2-1", "E1BBD9-1", "A0A3Q1N5B2-1", "A0ABI0P1A3-1", "F1MBQ1-1", "A0AAA9RTM1-1", "G3N3B3-1", "A0AAF6YJP2-1", "P48452-1", "O62829-1", "Q0IIF0-1", "A5PJZ2-1", "Q17QJ3-1", "F6RRD7-1", "Q5BIP9-1", "A0AAA9TT76-1", "Q0P594-1", "A6H772-1", "O62830-1", "P61287-1", "A0AAA9U0H6-1", "Q3SWW9-1", "Q3T0E7-1", "P0C591-1", "P67774-1", "Q0IID7-1", "Q1RMV9-1", "Q2KJ36-1", "P79126-1", "Q17QI2-1", "Q17QM8-1", "Q2KJD7-1", "E1B9Y5-1", "E1BIZ2-1", "F1MI99-1", "F1MP34-1", "F1MEZ2-1", "F1MQM7-1", "F1MM08-1", "F1N719-1", "A0AAA9T455-1", "Q58DC0-1", "A0AAA9SWY4-1", "A0A3Q1LZA9-1", "A0AAA9S454-1", "A0AAA9SCR0-1", "A0AAA9TD32-1", "A0AAA9TV14-1", "A0AAA9S745-1", "F1N580-1", "E1BMD4-1", "E1BF95-1", "E1BIE7-1", "A0A3Q1N224-1", "A0A3Q1MLC5-1", "A0A3Q1MH98-1", "F1MW70-1", "A0A3Q1MZU1-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LZA9", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] } ] }, { "uniprot_ac": "A0A3Q1MH98", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] } ] }, { "uniprot_ac": "A0A3Q1MLC5", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] } ] }, { "uniprot_ac": "A0A3Q1MV48", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] } ] }, { "uniprot_ac": "A0A3Q1MZU1", "gene_name": "CTDSPL2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZU1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZU1" } ] } ] }, { "uniprot_ac": "A0A3Q1N224", "gene_name": "PHLPP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N224" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1N224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N224" } ] } ] }, { "uniprot_ac": "A0A3Q1N5B2", "gene_name": "CDC14B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5B2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5B2" } ] } ] }, { "uniprot_ac": "A0AAA9RTM1", "gene_name": "DUSP22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": 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"O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWY4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9SWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWY4" } ] } ] }, { "uniprot_ac": "A0AAA9T455", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9T455", "database": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] } ] }, { "uniprot_ac": "A0AAF6DLF7", "gene_name": "DUSP7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] } ] }, { "uniprot_ac": "A0AAF6YJP2", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6YJP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6YJP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJP2" } ] } ] }, { "uniprot_ac": "A0ABI0P1A3", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0ABI0P1A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0ABI0P1A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3" } ] } ] }, { "uniprot_ac": "A5PJZ2", "gene_name": "PPM1L", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A5PJZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A5PJZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJZ2" } ] } ] }, { "uniprot_ac": "A6H772", "gene_name": "PPP4C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A6H772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H772" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A6H772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H772" } ] } ] }, { "uniprot_ac": "E1B9Y5", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1B9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Y5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1B9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Y5" } ] } ] }, { "uniprot_ac": "E1BAB2", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ] } ] }, { "uniprot_ac": "E1BBD9", "gene_name": "LOC112445820", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BBD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BBD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ] } ] }, { "uniprot_ac": "E1BEW5", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] } ] }, { "uniprot_ac": "E1BF95", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BF95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF95" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BF95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF95" } ] } ] }, { "uniprot_ac": "E1BIE7", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIE7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIE7" } ] } ] }, { "uniprot_ac": "E1BIZ2", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ2" } ] } ] }, { "uniprot_ac": "E1BMD4", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] } ] }, { "uniprot_ac": "F1MBQ1", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MBQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MBQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ1" } ] } ] }, { "uniprot_ac": "F1ME76", "gene_name": "DUSP13B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] } ] }, { "uniprot_ac": "F1MEZ2", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] } ] }, { "uniprot_ac": "F1MI92", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI92" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI92" } ] } ] }, { "uniprot_ac": "F1MI99", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] } ] }, { "uniprot_ac": "F1MM08", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] } ] }, { "uniprot_ac": "F1MP34", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] } ] }, { "uniprot_ac": "F1MQM7", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] } ] }, { "uniprot_ac": "F1MW70", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] } ] }, { "uniprot_ac": "F1N580", "gene_name": "PPM1E", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N580" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N580" } ] } ] }, { "uniprot_ac": "F1N719", "gene_name": "PPP5C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": 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"evidence": [ { "id": "G3N3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B3" } ] } ] }, { "uniprot_ac": "O62829", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] } ] }, { "uniprot_ac": "O62830", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O62830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62830" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O62830", "database": "UniProtKB", "url": 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"ENSBTAG00000030337", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000030337", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21937", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21937", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR026060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MMHYKEE", "url": "https://omabrowser.org/oma/group/MMHYKEE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A452DJ80", "url": "https://www.orthodb.org/?gene=A0A452DJ80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13168", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13168", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13168:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13168:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A452DJ80", "url": "https://www.uniprot.org/uniprotkb/A0A452DJ80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DJ80-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DJ80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1X9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1X9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1X9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1X9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTGHTPAIPARGSQVRRRPCPSAHEQCCSEPASHGLRRQLRRCRCHYGPLQSRRLEARAVPEVLGEVGGAGHADQGFLKHHLGAATPENPEIELLRLELAEMKEKYEAIVEENKKLKTKLAQYEPPQEEKRAE", "length": 134, "header": "tr|A0ABI0P1X9-1|A0ABI0P1X9_BOVIN Isoform 1 of MYC binding protein OS=Bos taurus OX=9913 GN=MYCBP PE=4 SV=1 CANONICAL=A0ABI0P1X9-1" }, "isoforms": [ { "isoform_ac": "A0A452DJ80-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1X9/entry#A0A452DJ80-1", "sequence": { "sequence": "MSSAAPSPPATVSGASYAAAAVTMAHYKAADSKREQFRRYLEKSGVLDTLTKVLVALYEEPEKPNSALDFLKHHLGAATPENPEIELLRLELAEMKEKYEAIVEENKKLKTKLAQYEPPQEEKRAE", "length": 126, "header": "tr|A0A452DJ80-1|A0ABI0P1X9_BOVIN Computationally mapped isoform of MYC binding protein OS=Bos taurus OX=9913 GN=MYCBP PE=4 SV=1 CANONICAL=A0ABI0P1X9-1" }, "locus": { "chromosome": "3", "start_pos": 107117628, "end_pos": 107111928, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000042835.4", "url": "https://www.ensembl.org/id/ENSBTAT00000042835.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040445.2", "url": "https://www.ensembl.org/id/ENSBTAP00000040445.2" } ] } }, { "isoform_ac": "A0ABI0P1X9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1X9/entry#A0ABI0P1X9-1", "sequence": { "sequence": "MKTGHTPAIPARGSQVRRRPCPSAHEQCCSEPASHGLRRQLRRCRCHYGPLQSRRLEARAVPEVLGEVGGAGHADQGFLKHHLGAATPENPEIELLRLELAEMKEKYEAIVEENKKLKTKLAQYEPPQEEKRAE", "length": 134, "header": "tr|A0ABI0P1X9-1|A0ABI0P1X9_BOVIN Isoform 1 of MYC binding protein OS=Bos taurus OX=9913 GN=MYCBP PE=4 SV=1 CANONICAL=A0ABI0P1X9-1" }, "locus": { "chromosome": "3", "start_pos": 107117628, "end_pos": 107111855, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154581.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154581.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106724.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106724.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZT87-1", "protein_name": "Myc binding protein", "gene_name": "Mycbp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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{ "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616091", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616091", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LS33", "url": "https://www.orthodb.org/?gene=A0A3Q1LS33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46460", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46460", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46460:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46460:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02870", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02870", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002698630", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698630", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24000", "url": "https://www.rhea-db.org/rhea/24000", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "53428", "url": "https://www.rhea-db.org/rhea/53428", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LPH3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LS33", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LS33-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3X2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3X2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAW2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RW79", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RW79-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7D3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7D3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7D3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBD1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBD1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NL65", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NL65-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0N3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0N3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDETCEMKYKVVDSPLGKLEISGCERGLHGIKLHGGKTPDTGPAEAAAPAEQLGGSGAVLEPLLQCAAWLDAYFREPAVLEGLPVPALHHPIFQKESFTRQVLWKLLTLVKFGETVSYQQLAALAGNPRAARAVGGAMRSNPIPILIPCHRVVCSSGAMGNYSGGVGVKEWLLAHEGRPAGKAARGGGSRATGSWRGALGSTASSQPAGRD", "length": 211, "header": "tr|A0ABI0P0N3-1|A0ABI0P0N3_BOVIN Isoform 1 of Methylated-DNA--protein-cysteine methyltransferase OS=Bos taurus OX=9913 GN=MGMT PE=3 SV=1 CANONICAL=A0ABI0P0N3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPH3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3/entry#A0A3Q1LPH3-1", "sequence": { "sequence": "MGCSSLALLWPLHVISVLAEGWLAWEEPKCNECRAPFLREVLGRMDETCEMKYKVVDSPLGKLEISGCERGLHGIKLHGGKTPDTGPAEAAAPAEQLGGSGAVLEPLLQCAAWLDAYFREPAVLEGLPVPALHHPIFQKESFTRQVLWKLLTLVKFGETVSYQQLAALAGNPRAARAVGGAMRSNPIPILIPCHRVVCSSGAMGNYSGGVGVKEWLLAHEGRPAGKAARGGGSRATGSWRGALGSTASSQPAGRD", "length": 255, "header": "tr|A0A3Q1LPH3-1|A0ABI0P0N3_BOVIN Computationally mapped isoform of Methylated-DNA--protein-cysteine methyltransferase OS=Bos taurus OX=9913 GN=MGMT PE=3 SV=1 CANONICAL=A0ABI0P0N3-1" }, "locus": { "chromosome": "26", "start_pos": 49095059, "end_pos": 48868772, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087196.3", "url": "https://www.ensembl.org/id/ENSBTAT00000087196.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056825.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056825.2" } ] } }, { "isoform_ac": "A0A3Q1LS33-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3/entry#A0A3Q1LS33-1", "sequence": { "sequence": "MWCSRGTQVPVRIGVLMRPGVSSGLGVPTRLGVPGAVESTALPEVLGRMDETCEMKYKVVDSPLGKLEISGCERGLHGIKLHGGKTPDTGPAEAAAPAEQLGGSGAVLEPLLQCAAWLDAYFREPAVLEGLPVPALHHPIFQKESFTRQVLWKLLTLVKFGETVSYQQLAALAGNPRAARAVGGAMRSNPIPILIPCHRVVCSSGAMGNYSGGVGVKEWLLAHEGRPAGKAARGGGSRATGSWRGALGSTASSQPAGRD", "length": 259, "header": "tr|A0A3Q1LS33-1|A0ABI0P0N3_BOVIN Computationally mapped isoform of Methylated-DNA--protein-cysteine methyltransferase OS=Bos taurus OX=9913 GN=MGMT PE=3 SV=2 CANONICAL=A0ABI0P0N3-1" }, "locus": { "chromosome": "26", "start_pos": 49095059, "end_pos": 48858237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083381.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083381.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063123.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063123.2" } ] } }, { "isoform_ac": "A0A3Q1M3X2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3/entry#A0A3Q1M3X2-1", "sequence": { "sequence": "MGCSSLALLWPLHVISVLAEGWLAWEEPKCNECRAPFLRESERAVSSEHLPGQPPVNTGAIVLRAELNCTVSVLGRMDETCEMKYKVVDSPLGKLEISGCERGLHGIKLHGGKTPDTGPAEAAAPAEQLGGSGAVLEPLLQCAAWLDAYFREPAVLEGLPVPALHHPIFQKESFTRQVLWKLLTLVKFGETVSYQQLAALAGNPRAARAVGGAMRSNPIPILIPCHRVVCSSGAMGNYSGGVGVKEWLLAHEGRPAGKAARGGGSRATGSWRGALGSTASSQPAGRD", "length": 287, "header": "tr|A0A3Q1M3X2-1|A0ABI0P0N3_BOVIN Computationally mapped isoform of Methylated-DNA--protein-cysteine methyltransferase OS=Bos taurus OX=9913 GN=MGMT PE=3 SV=1 CANONICAL=A0ABI0P0N3-1" }, "locus": { "chromosome": "26", "start_pos": 49095059, "end_pos": 48868772, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081192.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081192.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068246.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068246.2" } ] } }, { "isoform_ac": "A0A3Q1MAW2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3/entry#A0A3Q1MAW2-1", "sequence": { "sequence": "MTHQHFSHLNAPFMCVDSPWRFGLCLLWSYLKRHLLPAEAAAPAEQLGGSGAVLEPLLQCAAWLDAYFREPAVLEGLPVPALHHPIFQKESFTRQVLWKLLTLVKFGETVSYQQLAALAGNPRAARAVGGAMRSNPIPILIPCHRVVCSSGAMGNYSGGVGVKEWLLAHEGRPAGKAARGGGSRATGSWRGALGSTASSQPAGRD", "length": 205, "header": "tr|A0A3Q1MAW2-1|A0ABI0P0N3_BOVIN Computationally mapped isoform of Methylated-DNA--protein-cysteine methyltransferase OS=Bos taurus OX=9913 GN=MGMT PE=3 SV=2 CANONICAL=A0ABI0P0N3-1" }, "locus": { "chromosome": "26", "start_pos": 49095059, "end_pos": 48911299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072627.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072627.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067773.3", "url": "https://www.ensembl.org/id/ENSBTAP00000067773.3" } ] } }, { "isoform_ac": "A0AAA9RW79-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3/entry#A0AAA9RW79-1", "sequence": { "sequence": "MWCSRGTQVPVRIGVLMRPGVSSGLGVPTRLGVPGAVESTALPESERAVSSEHLPGQPPVNTGAIVLRAELNCTVSVLGRMDETCEMKYKVVDSPLGKLEISGCERGLHGIKLHGGKTPDTGPAEAAAPAEQLGGSGAVLEPLLQCAAWLDAYFREPAVLEGLPVPALHHPIFQKESFTRQVLWKLLTLVKFGETVSYQQLAALAGNPRAARAVGGAMRSNPIPILIPCHRVVCSSGAMGNYSGGVGVKEWLLAHEGRPAGKAARGGGSRATGSWRGALGSTASSQPAGRD", "length": 291, "header": "tr|A0AAA9RW79-1|A0ABI0P0N3_BOVIN Computationally mapped isoform of Methylated-DNA--protein-cysteine methyltransferase OS=Bos taurus OX=9913 GN=MGMT PE=3 SV=1 CANONICAL=A0ABI0P0N3-1" }, "locus": { "chromosome": "26", "start_pos": 49095059, "end_pos": 48858237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113457.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113457.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076638.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076638.1" } ] } }, { "isoform_ac": "A0AAA9S7D3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3/entry#A0AAA9S7D3-1", "sequence": { "sequence": "MREGFQSLQEVLAQPGWRVSEPPGGTGPAHQKGGSTLHVGSNKQCGAIAFQLWCSGYCSSACCHLTWKPAEAAAPAEQLGGSGAVLEPLLQCAAWLDAYFREPAVLEGLPVPALHHPIFQKESFTRQVLWKLLTLVKFGETVSYQQLAALAGNPRAARAVGGAMRSNPIPILIPCHRVVCSSGAMGNYSGGVGVKEWLLAHEGRPAGKAARGGGSRATGSWRGALGSTASSQPAGRD", "length": 237, "header": "tr|A0AAA9S7D3-1|A0ABI0P0N3_BOVIN Computationally mapped isoform of Methylated-DNA--protein-cysteine methyltransferase OS=Bos taurus OX=9913 GN=MGMT PE=3 SV=2 CANONICAL=A0ABI0P0N3-1" }, "locus": { "chromosome": "26", "start_pos": 49095059, "end_pos": 48931584, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116891.2", "url": "https://www.ensembl.org/id/ENSBTAT00000116891.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079222.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079222.1" } ] } }, { "isoform_ac": "A0AAA9TBD1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3/entry#A0AAA9TBD1-1", "sequence": { "sequence": "MGCSSLALLWPLHVISVLAEGWLAWEEPKCNECRAPFLREMSACGGAAGEVQGNALSRANPGLSVGRDTWKCCVQENLCKVTVLVKFIWSVFGTQRSREQSERAVSSEHLPGQPPVNTGAIVLRAELNCTVSVLGRMDETCEMKYKVVDSPLGKLEISGCERGLHGIKLHGGKTPDTGPAEAAAPAEQLGGSGAVLEPLLQCAAWLDAYFREPAVLEGLPVPALHHPIFQKESFTRQVLWKLLTLVKFGETVSYQQLAALAGNPRAARAVGGAMRSNPIPILIPCHRVVCSSGAMGNYSGGVGVKEWLLAHEGRPAGKAARGGGSRATGSWRGALGSTASSQPAGRD", "length": 347, "header": "tr|A0AAA9TBD1-1|A0ABI0P0N3_BOVIN Computationally mapped isoform of Methylated-DNA--protein-cysteine methyltransferase OS=Bos taurus OX=9913 GN=MGMT PE=3 SV=1 CANONICAL=A0ABI0P0N3-1" }, "locus": { "chromosome": "26", "start_pos": 49095059, "end_pos": 48868772, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094045.2", "url": "https://www.ensembl.org/id/ENSBTAT00000094045.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094153.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094153.1" } ] } }, { "isoform_ac": "A0ABI0NL65-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3/entry#A0ABI0NL65-1", "sequence": { "sequence": "MPCTLPAPGPSHRQSERAVSSEHLPGQPPVNTGAIVLRAELNCTVSVLGRMDETCEMKYKVVDSPLGKLEISGCERGLHGIKLHGGKTPDTGPAEAAAPAEQLGGSGAVLEPLLQCAAWLDAYFREPAVLEGLPVPALHHPIFQKESFTRQVLWKLLTLVKFGETVSYQQLAALAGNPRAARAVGGAMRSNPIPILIPCHRVVCSSGAMGNYSGGVGVKEWLLAHEGRPAGKAARGGGSRATGSWRGALGSTASSQPAGRD", "length": 261, "header": "tr|A0ABI0NL65-1|A0ABI0P0N3_BOVIN Computationally mapped isoform of Methylated-DNA--protein-cysteine methyltransferase OS=Bos taurus OX=9913 GN=MGMT PE=3 SV=1 CANONICAL=A0ABI0P0N3-1" }, "locus": { "chromosome": "26", "start_pos": 49095059, "end_pos": 48855971, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137276.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137276.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105712.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105712.1" } ] } }, { "isoform_ac": "A0ABI0P0N3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3/entry#A0ABI0P0N3-1", "sequence": { "sequence": "MDETCEMKYKVVDSPLGKLEISGCERGLHGIKLHGGKTPDTGPAEAAAPAEQLGGSGAVLEPLLQCAAWLDAYFREPAVLEGLPVPALHHPIFQKESFTRQVLWKLLTLVKFGETVSYQQLAALAGNPRAARAVGGAMRSNPIPILIPCHRVVCSSGAMGNYSGGVGVKEWLLAHEGRPAGKAARGGGSRATGSWRGALGSTASSQPAGRD", "length": 211, "header": "tr|A0ABI0P0N3-1|A0ABI0P0N3_BOVIN Isoform 1 of Methylated-DNA--protein-cysteine methyltransferase OS=Bos taurus OX=9913 GN=MGMT PE=3 SV=1 CANONICAL=A0ABI0P0N3-1" }, "locus": { "chromosome": "26", "start_pos": 49095059, "end_pos": 48870444, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138268.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138268.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104381.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104381.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:616091", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616091", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "methylated-DNA-[protein]-cysteine S-methyltransferase activity", "id": "GO:0003908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003908", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0N3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0N3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0N3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0N3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0N3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0N3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0N3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24000", "name": "", "equation": "a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = S-methyl-L-cysteinyl-[protein] + a 2'-deoxyguanosine in DNA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P0N3-1", "P29177-1" ], "evidence": [ { "id": "24000", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24000" } ] }, { "id": "53428", "name": "", "equation": "a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P0N3-1", "P29177-1" ], "evidence": [ { "id": "53428", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53428" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0ABI0P0N3", "gene_name": "MGMT", "activity": [ { "ec_number": "2.1.1.63", "activity": "a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = S-methyl-L-cysteinyl-[protein] + a 2'-deoxyguanosine in DNA.", "evidence": [ { "id": "A0ABI0P0N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3" } ] }, { "ec_number": "2.1.1.63", "activity": "", "evidence": [ { "id": "A0ABI0P0N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3" } ] } ] }, { "uniprot_ac": "P29177", "gene_name": "MGMT", "activity": [ { "ec_number": "2.1.1.63", "activity": "a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = S-methyl-L-cysteinyl-[protein] + a 2'-deoxyguanosine in DNA.", "evidence": [ { "id": "P29177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29177" } ] }, { "ec_number": "2.1.1.63", "activity": "", "evidence": [ { "id": "P29177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29177" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P0N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3" }, { "id": "PF01035", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding", "eco_id": "ECO_0000259", "start_pos": 100, "end_pos": 177, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P0N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0N3" }, { "id": "PF02870", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02870" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methylguanine DNA methyltransferase ribonuclease-like", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 86, "start_aa": "Met", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.63", "ec_name": "a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = S-methyl-L-cysteinyl-[protein] + a 2'-deoxyguanosine in DNA.", "evidence": [ { "id": "2.1.1.63", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.63" }, { "id": "2.1.1.63", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.63" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P218-1", "uniprot_ac": "A0ABI0P218", "uniprot_id": "A0ABI0P218_BOVIN", "mass": { "chemical_mass": 71699.0, "monoisotopic_mass": 71699.0 }, "refseq": {}, "gene_names": [ { "name": "UTP6", "type": "recommended", "evidence": [ { "id": "A0ABI0P218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218" } ] } ], "protein_names": [ { "name": "UTP6 small subunit processome component", "type": "synonym", "evidence": [ { "id": "A0ABI0P218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P218", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UTP6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218", "locus": { "chromosome": "19", "start_pos": 18250261, "end_pos": 18221895, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015612", "url": "https://www.ensembl.org/id/ENSBTAG00000015612" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015612", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015612", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LQ64", "url": "https://www.orthodb.org/?gene=A0A3Q1LQ64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LTN3", "url": "https://www.orthodb.org/?gene=A0A3Q1LTN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23271:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23271:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24892", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24892", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LQ64", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQ64-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LTN3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LTN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P218", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P218-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R8I1", "url": "https://www.uniprot.org/uniprotkb/F6R8I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R8I1-1", "url": "https://www.uniprot.org/uniprotkb/F6R8I1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEVIQERVEDRLPELQQLERTGLFSHAEINGFLLRAIIRKALELEYRIQRRSLLKDDFIRYVQYEIHLLDLIEKRRARVGYTFKKDEIEDPIIHRIQSVFRRASIKWKDDVRLWLSFIAFCRKWASNVHLSKIFSSLLAFHSNKPGLWILAAKWELEDRFSSESARQLFLRALRFHPRCPKLYEEYFRMELMHAEKLRKEKQEFEKANMDVGNLEHAEEILTGELARIIYKNSTSVIKSAKFHVSLLSIARLFDFAKDLQREIYNDLKALHADDPVTWDYVARQELVIESQPVEELPATKQAKAKEVGRREERCCAVYEEAVKTVPTEAMWKCYMNFCMERFTKKTSSRLLRKKRLERTMVAFWKAHELKLLPELQYRQLSKLLLHRQLLKESLEVADAGVKLFKKSVEMWQVKLEALITSESHEMSKGFEQAFEYLKPQICLPLWLTWAQWSEDAGKQEETEAIYKRAIFGLPGADSVPVKEMYLNWAYRSGGYKKARDVFKSLQENRPFSVDFFRKMIQFEKEQESCKMENLREYYERALREFGTNDSDLWMDYIKEELNHPLGRPENCGQIYWRAMKMLQGESVEQFMAKHALYQAGRL", "length": 603, "header": "tr|A0ABI0P218-1|A0ABI0P218_BOVIN Isoform 1 of UTP6 small subunit processome component OS=Bos taurus OX=9913 GN=UTP6 PE=3 SV=1 CANONICAL=A0ABI0P218-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQ64-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218/entry#A0A3Q1LQ64-1", "sequence": { "sequence": "MAEVIQERVEDRLPELQQLERTGLFSHAEIKAIIRKALELEYRIQRRSLLKDDFIRYVQYEIHLLDLIEKRRARVGYTFKKDEIEDPIIHRIQSVFRRASIKWKDDVRLWLSFIAFCRKWASNVHLSKIFSSLLAFHSNKPGLWILAAKWELEDRFSSESARQLFLRALRFHPRCPKLYEEYFRMELMHAEKLRKEKQEFEKANMDVGNLEHAEEILTGELARIIYKNSTSVIKSAKFHVSLLSIARLFDFAKDLQREIYNDLKALHADDPVTWDYVARQELVIESQPVEELPATKQAKAKEVGRREERCCAVYEEAVKTVPTEAMWKCYMNFCMERFTKKTSSRLLRKKRLERTMVAFWKAHELKLLPELQYRQLSKLLLHRQLLKESLEVADAGVKLFKKSVEMWQVKLEALITSESHEMSKGFEQAFEYLKPQICLPLWLTWAQWSEDAGKQEETEAIYKRAIFGLPGADSVPVKEMYLNWAYRSGGYKKARDVFKSLQENRPFSVDFFRKMIQFEKEQPLFHRCDFRNGSQAKKKRNLS", "length": 543, "header": "tr|A0A3Q1LQ64-1|A0ABI0P218_BOVIN Computationally mapped isoform of UTP6 small subunit processome component OS=Bos taurus OX=9913 GN=UTP6 PE=3 SV=2 CANONICAL=A0ABI0P218-1" }, "locus": { "chromosome": "19", "start_pos": 18244324, "end_pos": 18222023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077907.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077907.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057101.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057101.2" } ] } }, { "isoform_ac": "A0A3Q1LTN3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218/entry#A0A3Q1LTN3-1", "sequence": { "sequence": "MAEVIQERVEDRLPELQQLERTGLFSHAEIKAIIRKALELEYRIQRRSLLKDDFIRYVQYEIHLLDLIEKRRARVGYTFKKDEIEDPIIHRIQSVFRRASIKWKDDVRLWLSFIAFCRKWASNVHLSKIFSSLLAFHSNKPGLWILAAKWELEDRFSSESARQLFLRALRFHPRCPKLYEEYFRMELMHAEKLRKEKQEFEKANMDVGNLEHAEEILTGELARIIYKNSTSVIKSAKFHVSLLSIARLFDFAKDLQREIYNDLKALHADDPVTWDYVARQELVIESQPVEELPATKQAKAKEVGRREERCCAVYEEAVKTVPTEAMWKCYMNFCMERFTKKTSSRLLRKKRLERTMVAFWKAHELKLLPELQYRQLSKLLLHRQLLKESLEVADAGVKLFKKSVEMWQVKLEALITSESHEMSKGFEQAFEYLKPQICLPLWLTWAQWSEDAGKQEETEAIYKRAIFGLPGADSVPVKEMYLNWAYRSGGYKKARDVFKSLQENRPFSVDFFRKMIQFEKEQESCKMENLREYYERALREFGTNDSGKNT", "length": 550, "header": "tr|A0A3Q1LTN3-1|A0ABI0P218_BOVIN Computationally mapped isoform of UTP6 small subunit processome component OS=Bos taurus OX=9913 GN=UTP6 PE=3 SV=2 CANONICAL=A0ABI0P218-1" }, "locus": { "chromosome": "19", "start_pos": 18250054, "end_pos": 18222023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071816.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071816.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060702.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060702.2" } ] } }, { "isoform_ac": "A0ABI0P218-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218/entry#A0ABI0P218-1", "sequence": { "sequence": "MAEVIQERVEDRLPELQQLERTGLFSHAEINGFLLRAIIRKALELEYRIQRRSLLKDDFIRYVQYEIHLLDLIEKRRARVGYTFKKDEIEDPIIHRIQSVFRRASIKWKDDVRLWLSFIAFCRKWASNVHLSKIFSSLLAFHSNKPGLWILAAKWELEDRFSSESARQLFLRALRFHPRCPKLYEEYFRMELMHAEKLRKEKQEFEKANMDVGNLEHAEEILTGELARIIYKNSTSVIKSAKFHVSLLSIARLFDFAKDLQREIYNDLKALHADDPVTWDYVARQELVIESQPVEELPATKQAKAKEVGRREERCCAVYEEAVKTVPTEAMWKCYMNFCMERFTKKTSSRLLRKKRLERTMVAFWKAHELKLLPELQYRQLSKLLLHRQLLKESLEVADAGVKLFKKSVEMWQVKLEALITSESHEMSKGFEQAFEYLKPQICLPLWLTWAQWSEDAGKQEETEAIYKRAIFGLPGADSVPVKEMYLNWAYRSGGYKKARDVFKSLQENRPFSVDFFRKMIQFEKEQESCKMENLREYYERALREFGTNDSDLWMDYIKEELNHPLGRPENCGQIYWRAMKMLQGESVEQFMAKHALYQAGRL", "length": 603, "header": "tr|A0ABI0P218-1|A0ABI0P218_BOVIN Isoform 1 of UTP6 small subunit processome component OS=Bos taurus OX=9913 GN=UTP6 PE=3 SV=1 CANONICAL=A0ABI0P218-1" }, "locus": { "chromosome": "19", "start_pos": 18247618, "end_pos": 18222023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144109.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144109.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107188.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107188.1" } ] } }, { "isoform_ac": "F6R8I1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218/entry#F6R8I1-1", "sequence": { "sequence": "MAIIRKALELEYRIQRRSLLKDDFIRYVQYEIHLLDLIEKRRARVGYTFKKDEIEDPIIHRIQSVFRRASIKWKDDVRLWLSFIAFCRKWASNVHLSKIFSSLLAFHSNKPGLWILAAKWELEDRFSSESARQLFLRALRFHPRCPKLYEEYFRMELMHAEKLRKEKQEFEKANMDVGNLEHAEEILTGELARIIYKNSTSVIKSAKFHVSLLSIARLFDFAKDLQREIYNDLKALHADDPVTWDYVARQELVIESQPVEELPATKQAKAKEVGRREERCCAVYEEAVKTVPTEAMWKCYMNFCMERFTKKTSSRLLRKKRLERTMVAFWKAHELKLLPELQYRQLSKLLLHRQLLKESLEVADAGVKLFKKSVEMWQVKLEALITSESHEMSKGFEQAFEYLKPQICLPLWLTWAQWSEDAGKQEETEAIYKRAIFGLPGADSVPVKEMYLNWAYRSGGYKKARDVFKSLQENRPFSVDFFRKMIQFEKEQESCKMENLREYYERALREFGTNDSDLWMDYIKEELNHPLGRPENCGQIYWRAMKMLQGESVEQFMAKHALYQAGRL", "length": 568, "header": "tr|F6R8I1-1|A0ABI0P218_BOVIN Computationally mapped isoform of UTP6 small subunit processome component OS=Bos taurus OX=9913 GN=UTP6 PE=3 SV=2 CANONICAL=A0ABI0P218-1" }, "locus": { "chromosome": "19", "start_pos": 18247618, "end_pos": 18209367, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020740.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020740.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020740.6", "url": "https://www.ensembl.org/id/ENSBTAP00000020740.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P218", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "snoRNA binding", "id": "GO:0030515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P218", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P218", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 549, "end_pos": 551, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218" }, { "id": "PF08640", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08640" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U3 small nucleolar RNA-associated protein 6 N-terminal", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 96, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P218" }, { "id": "PF24892", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24892" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U3 small nucleolar RNA-associated protein 6 homolog C-terminal", "eco_id": "ECO_0000259", "start_pos": 313, "end_pos": 583, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 233, "end_pos": 235 }, { "start_pos": 549, "end_pos": 551 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P361-1", "uniprot_ac": "A0ABI0P361", "uniprot_id": "A0ABI0P361_BOVIN", "mass": { "chemical_mass": 121849.0, "monoisotopic_mass": 121849.0 }, "refseq": {}, "gene_names": [ { "name": "LIMCH1", "type": "recommended", "evidence": [ { "id": "A0ABI0P361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361" } ] } ], "protein_names": [ { "name": "LIM and calponin homology domains 1", "type": "synonym", "evidence": [ { "id": "A0ABI0P361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P361", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LIMCH1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361", "locus": { "chromosome": "6", "start_pos": 60573879, "end_pos": 60223942, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010677", "url": "https://www.ensembl.org/id/ENSBTAG00000010677" } ] } } ], "crossref": [ { "id": "ENSBTAG00000010677", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010677", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08368", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08368", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21278", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21278", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "535165", "url": "https://www.ncbi.nlm.nih.gov/gene/535165", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15551", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15551", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15551:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15551:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15949", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15949", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LR09", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LR09-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0L9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0L9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2M8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2M8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MKV4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MKV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MRR5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MRR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXL5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXL5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P361", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P361-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BC91", "url": "https://www.uniprot.org/uniprotkb/E1BC91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BC91-1", "url": "https://www.uniprot.org/uniprotkb/E1BC91-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACPVLGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVAVKSLDYSRKLKNVLVTIYWLGKAANSCASYSGTTLNLKEFEGLLAQMRKETDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINSQLREEDDKWQDDLARWKSRRRSASQDLIRKEEERKKMEKLLAGEDGTRERRKSIKTYREIVQEKERRERELHEAYKNARTQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSPFLSDPNPMKYLRQQSLPPPKFTATVETTIARPSVLDASMSAGSGSPSKTVSPKAVPMLTPKPYSQPKNSQEVLKTFKVDGKVTMNGETTHGDEEEKERECPTVALAPSLTKSQMFEGEARVHGSPVELKQDSNSIEINIKKPSSLPQELTATTEETEANSREDENDGEEAEKGNTEVAPSEPQLFTTTVTRSSPTVAFVELSPSPQLKNEVPEEKEQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPETNQSPLPNLNSQVDSPSSEKSPVTTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSVTEGSGTVNKMDLENCCEEEQETRQKRPLQEDNSDSLLKTREGDPLEEKGSSLTQEVLTHSENPASEGIYHQLDTEAGAPQCGVNPQLAQDPSQNQQVSNPPMHILEDVKPKTLPLDKSINHQIESPSERRKKSPRENFQAGRLSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFKCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL", "length": 1083, "header": "tr|A0ABI0P361-1|A0ABI0P361_BOVIN Isoform 1 of LIM and calponin homology domains 1 OS=Bos taurus OX=9913 GN=LIMCH1 PE=4 SV=1 CANONICAL=A0ABI0P361-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LR09-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361/entry#A0A3Q1LR09-1", "sequence": { "sequence": "MACPVLGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVAVKSLDYSRKLKNVLVTIYWLGKAANSCASYSGTTLNLKEFEGLLAQMRKETDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINSQLREEDDKWQDDLARWKSRRRSASQDLIRKEEERKKMEKLLAGEDGTRERRKSIKTYREIVQEKERRERELHEAYKNARTQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSPFLSDPNPMKYLRQQSLPPPKFTATVETTIARPSVLDASMSAGSGSPSKTVSPKAVPMLTPKPYSQPKNSQEVLKTFKVDGKVTMNGETTHGDEEEKERECPTVALAPSLTKSQMFEGEARVHGSPVELKQDSNSIEINIKKPSSLPQELTATTEETEANSREDENDGEEAEKGNTEVAPSEPQLFTTTVTRSSPTVAFVELSPSPQLKNEVPEEKEQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPETNQSPLPNLNSQESPGTASIPLRVQNSWRRSQFFSQSVDSPSSEKSPVTTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSVTEGSGTVNKMDLENCCEEEQETRQKRPLQEDNSDSLLKTREGDPLEEKGSSLTQEVLTHSENPASEGIYHQLDTEAGAPQCGVNPQLAQDPSQNQQVSNPPMHILEDVKPKTLPLDKSINHQIESPSERRKKSPRENFQAGRLSPCSPTPPGQSPNRYKRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFKCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL", "length": 1099, "header": "tr|A0A3Q1LR09-1|A0ABI0P361_BOVIN Computationally mapped isoform of LIM and calponin homology domains 1 OS=Bos taurus OX=9913 GN=LIMCH1 PE=4 SV=3 CANONICAL=A0ABI0P361-1" }, "locus": { "chromosome": "6", "start_pos": 60572875, "end_pos": 60224141, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080808.3", "url": "https://www.ensembl.org/id/ENSBTAT00000080808.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062672.3", "url": "https://www.ensembl.org/id/ENSBTAP00000062672.3" } ] } }, { "isoform_ac": "A0A3Q1M0L9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361/entry#A0A3Q1M0L9-1", "sequence": { "sequence": "MLRHWREQGFYYNMRETDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINSQLREEDDKWQDDLARWKSRRRSASQDLIRKEEERKKMEKLLAGEDGTRERRKSIKTYREIVQEKERRERELHEAYKNARTQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSPFLSDPNPMKYLRQQSLPPPKFTATVETTIARPSVLDASMSAGSGSPSKTVSPKAVPMLTPKPYSQPKNSQEVLKTFKVDGKVTMNGETTHGDEEEKERECPTVALAPSLTKSQMFEGEARVHGSPVELKQDSNSIEINIKKPSSLPQELTATTEETEANSREDENDGEEAEKGNTEVAPSEPQLFTTTVTRSSPTVAFVELSPSPQLKNEVPEEKEQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPETNQSPLPNLNSQVDSPSSEKSPVTTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSVTEGSGTVNKMDLENCCEEEQETRQKRPLQEDNSDSLLKTREGDPLEEKGSLTQEVLTHSENPASEGIYHQLDTEAGAPQCGVNPQLAQDPSQNQQVSNPPMHILEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFKCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL", "length": 897, "header": "tr|A0A3Q1M0L9-1|A0ABI0P361_BOVIN Computationally mapped isoform of LIM and calponin homology domains 1 OS=Bos taurus OX=9913 GN=LIMCH1 PE=4 SV=2 CANONICAL=A0ABI0P361-1" }, "locus": { "chromosome": "6", "start_pos": 60572875, "end_pos": 60489259, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083472.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083472.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066759.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066759.2" } ] } }, { "isoform_ac": "A0A3Q1M2M8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361/entry#A0A3Q1M2M8-1", "sequence": { "sequence": "MACPVLGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVAVKSLDYSRKLKNVLVTIYWLGKAANSCASYSGTTLNLKEFEGLLAQMRKETDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINSQLREEDDKWQDDLARWKSRRRSASQDLIRKEEERKKMEKLLAGEDGTRERRKSIKTYREIVQEKERRERELHEAYKNARTQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSPFLSDPNPMKYLRQQSLPPPKFTATVETTIARPSVLDASMSAGSGSPSKTVSPKAVPMLTPKPYSQPKNSQEVLKTFKVDGKVTMNGETTHGDEEEKERECPTVALAPSLTKSQMFEGEARVHGSPVELKQDSNSIEINIKKPSSLPQELTATTEETEANSREDENDGEEAEKGNTEVAPSEPQLFTTTVTRSSPTVAFVELSPSPQLKNEVPEEKEQKKPENEMSGKVELVLSQKERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSVTEGSGTVNKMDLENCCEEEQETRQKRPLQEDNSDSLLKTREGDPLEEKGSLTQEVLTHSENPASEGIYHQLDTEAGAPQCGVNPQLAQDPSQNQQVSNPPMHILEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFKCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL", "length": 980, "header": "tr|A0A3Q1M2M8-1|A0ABI0P361_BOVIN Computationally mapped isoform of LIM and calponin homology domains 1 OS=Bos taurus OX=9913 GN=LIMCH1 PE=4 SV=2 CANONICAL=A0ABI0P361-1" }, "locus": { "chromosome": "6", "start_pos": 60572875, "end_pos": 60224141, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081117.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081117.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064061.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064061.2" } ] } }, { "isoform_ac": "A0A3Q1MKV4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361/entry#A0A3Q1MKV4-1", "sequence": { "sequence": "MLRLCQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVAVKSLDYSRKLKNVLVTIYWLGKAANSCASYSGTTLNLKEFEGLLAQMRKETDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINSQLREEDDKWQDDLARWKSRRRSASQDLIRKEEERKKMEKLLAGEDGTRERRKSIKTYREIVQEKERRERELHEAYKNARTQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSPFLSDPNPMKYLRQQSLPPPKFTATVETTIARPSVLDASMSAGSGSPSKTVSPKAVPMLTPKPYSQPKNSQEVLKTFKVDGKVTMNGETTHGDEEEKERECPTVALAPSLTKSQMFEGEARVHGSPVELKQDSNSIEINIKKPSSLPQELTATTEETEANSREDENDGEEAEKGNTEVAPSEPQLFTTTVTRSSPTVAFVELSPSPQLKNEVPEEKEQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPETNQSPLPNLNSQESPGTASIPLRVQNSWRRSQFFSQSVDSPSSEKSPVTTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSVTEGSGTVNKMDLENCCEEEQETRQKRPLQEDNSDSLLKTREGDPLEEKGSSLTQEVLTHSENPASEGIYHQLDTEAGAPQCGVNPQLAQDPSQNQQVSNPPMHILEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFKCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL", "length": 1043, "header": "tr|A0A3Q1MKV4-1|A0ABI0P361_BOVIN Computationally mapped isoform of LIM and calponin homology domains 1 OS=Bos taurus OX=9913 GN=LIMCH1 PE=4 SV=2 CANONICAL=A0ABI0P361-1" }, "locus": { "chromosome": "6", "start_pos": 60572875, "end_pos": 60240080, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082358.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082358.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069883.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069883.2" } ] } }, { "isoform_ac": "A0A3Q1MRR5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361/entry#A0A3Q1MRR5-1", "sequence": { "sequence": "MACPVLGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVAVKSLDYSRKLKNVLVTIYWLGKAANSCASYSGTTLNLKEFEGLLAQMRKETDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFSYPETIEEEEGEVGSHCEEDPVSQMDTSGKPPDGGSELPTSCGKEQPPPEGAVVAPAPKSEEKAAAEMQKRRRLEQAGIKVMPAAQRFASQKQLNDEKEAVRNIILRKENPFLVHQHGRDSESEDEVACRLPDLEKDDFAARRARMNQTKPVVPLNQLLYGPYRKKEAEKSDGSKQHSKGISEKKTLEHKRNQGQTEEVKSRVTCIVRAQESEPAEAGLRKVPDLYKDDLAQRRIQSRLGPHREAPSFITVASITEADLETWERLKVSEKTRDGDVEHTCAPEPSPEIKAETAIRDDFASRKARAYKKASSSPRQKFVHFGPVTEIDQQTWKRLSIGRAGPRADAEEGISHDSKTHTCAVSAASAATSSLKEDRMLNPQNDCRTVTSDVDDCCKRVSQLAPVPESQEERSFSAGEGPRRTEEVTRKQQPQDRKEEPEGVAQRDSEMAPKAERSEEGGQPLHPVTSEWEASEREEKLEKMTAPVWSHSGPKGQRKLYNSQKDDMMTWRTGMSRSHIGSNNQFLPVAFAKQHIWEESAKGPPIKDKRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINSQLREEDDKWQDDLARWKSRRRSASQDLIRKEEERKKMEKLLAGEDGTRERRKSIKTYREIVQEKERRERELHEAYKNARTQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSPFLSDPNPMKYLRQQSLPPPKFTATVETTIARPSVLDASMSAGSGSPSKTVSPKAVPMLTPKPYSQPKNSQEVLKTFKVDGKVTMNGETTHGDEEEKERECPTVALAPSLTKSQMFEGEARVHGSPVELKQDSNSIEINIKKPSSLPQELTATTEETEANSREDENDGEEAEKGNTEVAPSEPQLFTTTVTRSSPTVAFVELSPSPQLKNEVPEEKEQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPETNQSPLPNLNSQVDSPSSEKSPVTTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSVTEGSGTVNKMDLENCCEEEQETRQKRPLQEDNSDSLLKTREGDPLEEKGSLTQEVLTHSENPASEGIYHQLDTEAGAPQCGVNPQLAQDPSQNQQVSNPPMHILEDVKPKTLPLDKSINHQIESPSERRKKSPRENFQAGRLSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFKCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL", "length": 1626, "header": "tr|A0A3Q1MRR5-1|A0ABI0P361_BOVIN Computationally mapped isoform of LIM and calponin homology domains 1 OS=Bos taurus OX=9913 GN=LIMCH1 PE=4 SV=2 CANONICAL=A0ABI0P361-1" }, "locus": { "chromosome": "6", "start_pos": 60572875, "end_pos": 60224141, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079657.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079657.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057058.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057058.2" } ] } }, { "isoform_ac": "A0AAA9TXL5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361/entry#A0AAA9TXL5-1", "sequence": { "sequence": "MDPERRVKETDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINSQLREEDDKWQDDLARWKSRRRSASQDLIRKEEERKKMEKLLAGEDGTRERRKSIKTYREIVQEKERRERELHEAYKNARTQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSPFLSDPNPMKYLRQQSLPPPKFTATVETTIARPSVLDASMSAGSGSPSKTVSPKAVPMLTPKPYSQPKNSQEVLKTFKVDGKVTMNGETTHGDEEEKERECPTVALAPSLTKSQMFEGEARVHGSPVELKQDSNSIEINIKKPSSLPQELTATTEETEANSREDENDGEEAEKGNTEVAPSEPQLFTTTVTRSSPTVAFVELSPSPQLKNEVPEEKEQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPETNQSPLPNLNSQVDSPSSEKSPVTTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSVTEGSGTVNKMDLENCCEEEQETRQKRPLQEDNSDSLLKTREGDPLEEKGSLTQEVLTHSENPASEGIYHQLDTEAGAPQCGVNPQLAQDPSQNQQVSNPPMHILEDVKPKTLPLDKSINHQIESPSERRKKSPRENFQAGRLSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFKCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL", "length": 916, "header": "tr|A0AAA9TXL5-1|A0ABI0P361_BOVIN Computationally mapped isoform of LIM and calponin homology domains 1 OS=Bos taurus OX=9913 GN=LIMCH1 PE=4 SV=1 CANONICAL=A0ABI0P361-1" }, "locus": { "chromosome": "6", "start_pos": 60572875, "end_pos": 60489749, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126049.2", "url": "https://www.ensembl.org/id/ENSBTAT00000126049.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101391.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101391.1" } ] } }, { "isoform_ac": "A0ABI0P361-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361/entry#A0ABI0P361-1", "sequence": { "sequence": "MACPVLGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVAVKSLDYSRKLKNVLVTIYWLGKAANSCASYSGTTLNLKEFEGLLAQMRKETDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINSQLREEDDKWQDDLARWKSRRRSASQDLIRKEEERKKMEKLLAGEDGTRERRKSIKTYREIVQEKERRERELHEAYKNARTQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSPFLSDPNPMKYLRQQSLPPPKFTATVETTIARPSVLDASMSAGSGSPSKTVSPKAVPMLTPKPYSQPKNSQEVLKTFKVDGKVTMNGETTHGDEEEKERECPTVALAPSLTKSQMFEGEARVHGSPVELKQDSNSIEINIKKPSSLPQELTATTEETEANSREDENDGEEAEKGNTEVAPSEPQLFTTTVTRSSPTVAFVELSPSPQLKNEVPEEKEQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPETNQSPLPNLNSQVDSPSSEKSPVTTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSVTEGSGTVNKMDLENCCEEEQETRQKRPLQEDNSDSLLKTREGDPLEEKGSSLTQEVLTHSENPASEGIYHQLDTEAGAPQCGVNPQLAQDPSQNQQVSNPPMHILEDVKPKTLPLDKSINHQIESPSERRKKSPRENFQAGRLSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFKCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL", "length": 1083, "header": "tr|A0ABI0P361-1|A0ABI0P361_BOVIN Isoform 1 of LIM and calponin homology domains 1 OS=Bos taurus OX=9913 GN=LIMCH1 PE=4 SV=1 CANONICAL=A0ABI0P361-1" }, "locus": { "chromosome": "6", "start_pos": 60572875, "end_pos": 60224141, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136792.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136792.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105681.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105681.1" } ] } }, { "isoform_ac": "E1BC91-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361/entry#E1BC91-1", "sequence": { "sequence": "MACPVLGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVAVKSLDYSRKLKNVLVTIYWLGKAANSCASYSGTTLNLKEFEGLLAQMRKETDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINSQLREEDDKWQDDLARWKSRRRSASQDLIRKEEERKKMEKLLAGEDGTRERRKSIKTYREIVQEKERRERELHEAYKNARTQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSPFLSDPNPMKYLRQQSLPPPKFTATVETTIARPSVLDASMSAGSGSPSKTVSPKAVPMLTPKPYSQPKNSQEVLKTFKVDGKVTMNGETTHGDEEEKERECPTVALAPSLTKSQMFEGEARVHGSPVELKQDSNSIEINIKKPSSLPQELTATTEETEANSREDENDGEEAEKGNTEVAPSEPQLFTTTVTRSSPTVAFVELSPSPQLKNEVPEEKEQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPETNQSPLPNLNSQESPGTASIPLRVQNSWRRSQFFSQSVDSPSSEKSPVTTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSVTEGSGTVNKMDLENCCEEEQETRQKRPLQEDNSDSLLKTREGDPLEEKGSSLTQEVLTHSENPASEGIYHQLDTEAGAPQCGVNPQLAQDPSQNQQVSNPPMHILEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFKCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL", "length": 1083, "header": "tr|E1BC91-1|A0ABI0P361_BOVIN Computationally mapped isoform of LIM and calponin homology domains 1 OS=Bos taurus OX=9913 GN=LIMCH1 PE=4 SV=5 CANONICAL=A0ABI0P361-1" }, "locus": { "chromosome": "6", "start_pos": 60572875, "end_pos": 60224141, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039655.7", "url": "https://www.ensembl.org/id/ENSBTAT00000039655.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000039445.7", "url": "https://www.ensembl.org/id/ENSBTAP00000039445.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 997, "start_aa": "Thr", "end_pos": 997, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr997", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P361", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P361", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361" } ], "pmid": "" }, { "name": "myosin II head/neck binding", "id": "GO:0032034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032034", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P361", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P361", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361" } ], "pmid": "" }, { "name": "positive regulation of macromolecule metabolic process", "id": "GO:0010604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010604", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P361", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361" } ], "pmid": "" }, { "name": "regulation of primary metabolic process", "id": "GO:0080090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080090", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P361", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361" } ], "pmid": "" }, { "name": "regulation of focal adhesion assembly", "id": "GO:0051893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051893", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P361", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P361", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P361", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P361", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1004, "end_pos": 1006, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 475, "end_pos": 477, "annotation": "n_glycosylation_sequon" }, { "start_pos": 738, "end_pos": 740, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 138, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P361", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P361" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 1011, "end_pos": 1077, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 997 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1004, "end_pos": 1006 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 475, "end_pos": 477 }, { "start_pos": 738, "end_pos": 740 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P3K7-1", "uniprot_ac": "A0ABI0P3K7", "uniprot_id": "A0ABI0P3K7_BOVIN", "mass": { "chemical_mass": 34778.0, "monoisotopic_mass": 34778.0 }, "refseq": { "ac": "XP_003586956", "name": "fibrinogen silencer-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586956" }, "gene_names": [ { "name": "FSBP", "type": "recommended", "evidence": [ { "id": "A0ABI0P3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7" } ] }, { "name": "FSBP", "type": "synonym", "evidence": [ { "id": "XP_003586956", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586956" } ] } ], "protein_names": [ { "name": "Fibrinogen silencer binding protein", "type": "synonym", "evidence": [ { "id": "A0ABI0P3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7/entry#names_and_taxonomy" } ] }, { "name": "fibrinogen silencer-binding protein", "type": "synonym", "evidence": [ { "id": "XP_003586956", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586956" } ] } ], "function": [ { "annotation": "Multifunctional ATPase that could play with RAD54, a redundant role in homologous recombination (HR), a major pathway for repairing DNA double-strand breaks (DSBs), single-stranded DNA (ssDNA) gaps, and stalled or collapsed replication forks. Could act as a molecular motor during the homology search and guide RAD51 ssDNA along a donor dsDNA thereby changing the homology search from the diffusion-based mechanism to a motor-guided mechanism. Once DNA strand exchange occured, could dissociate RAD51 from nucleoprotein filaments formed on dsDNA. May also function as a molecular adapter, promoting MDM2-MDM4 heterodimerization to facilitate the ubiquitin-dependent degradation of p53, thereby modulating the cellular decision between cell cycle arrest and progression in response to DNA damage.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NJU3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJU3#function" }, { "database": "UniProtKB", "id": "ARBA00094108", "url": "https://www.uniprot.org/uniprotkb/ARBA00094108#function" }, { "database": "UniProtKB", "id": "A0ABI0NMV1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV1#function" }, { "database": "UniProtKB", "id": "A0ABI0P814", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P814#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FSBP", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7", "locus": { "chromosome": "14", "start_pos": 69911873, "end_pos": 69905996, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000024984", "url": "https://www.ensembl.org/id/ENSBTAG00000024984" } ] } } ], "crossref": [ { "id": "ENSBTAG00000024984", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000024984", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100848732", "url": "https://www.ncbi.nlm.nih.gov/gene/100848732", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "533414", "url": "https://www.ncbi.nlm.nih.gov/gene/533414", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028002", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028002", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100848732", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100848732", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERNNLPC", "url": "https://omabrowser.org/oma/group/ERNNLPC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BJC3", "url": "https://www.orthodb.org/?gene=E1BJC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15386", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15386", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15386:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15386:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45629", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45629", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45629:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45629:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13873", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003586956", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586956", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NJU3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJU3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMV1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMV1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3K7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3K7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P814", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P814", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P814-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P814-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJC3", "url": "https://www.uniprot.org/uniprotkb/E1BJC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BJC3-1", "url": "https://www.uniprot.org/uniprotkb/E1BJC3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLKLVKPYVKILEEHTNKHSVIVEKNRCWDIIAVNYNAIGVDRPPRTAQGLRTLYKRLKEYAKQELLQQKETQSDFKSNISEPTKKVMEMIPQISSFCLVRDRNHIQSANLDEEAQAGTSSLQVMLDRHPVAITVEVKQEEDIKPPLPLVLNSQQSDTLEQREEQELVRVMERSLSPSLSSVDMRMTSSPSSIPRRDDFFRHESGENFRSQLGYDPQILQMLKEEHQIILENQKSFGLYVQEKRDGLKRRQQLEEELLRAKIEVEKLKAIRLRHDLPEYNSL", "length": 299, "header": "tr|A0ABI0P3K7-1|A0ABI0P3K7_BOVIN Isoform 1 of Fibrinogen silencer binding protein OS=Bos taurus OX=9913 GN=FSBP PE=4 SV=1 CANONICAL=A0ABI0P3K7-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NJU3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7/entry#A0ABI0NJU3-1", "sequence": { "sequence": "MDRGAWWATVHGVAKSRTGLSDFTFFLMELEGGKQKQQGRLILLNMRRSAAPSQLQGNPFKKPKFISPARSHPSPNEEVAKLNSDIKLFEVAANKNNFLQPQNDPRTCNFNLPTKECAKGINHGDNYREKYCLEASTKTTLDLHHTGTGYKLKELEKIEEGQTMMIGGKEIEVMGIISPDDFNSGRCFQFGGGCSAILSSSQAAKKCFSNPFKSVCKLSSKENKQNSFQSCKPRHDPYAPNSLVMLRPDKNHQWLFNKNCFPVVDVVIDPHLVYYLRPHQKEGITFLYECVMGMRVNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPIVKKTLIVTPGSLVNNWKKEFQKWLGIERIKIFTVDQDHKVEEFTKSPFYSVLIISYEMLLRSLDQIKNVKFDLLICDEGHRLKNSTIKTTTALISLSCEKRIILTGTPVQNDLQEFFTLIDFVNPGILGSLSAYRKIYEEPIIISRQPSASEEERELGEQRAAELTCLTGLFILRRTQEVINQYLPPKIENVVFCRPGALQIALYRKLLNSQAVRFCLQGLLENTSHLICIGALKKLCNHPCLLFGSIKEKESNSTWDESEERNLYEGLMNVFPADYNPIMFTEEESGKLQVLSKLLAVIRELRPAEKVVLVSNYTRTLDILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSKYSSDFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKHPVHIYRLLTTGTIEEKIYQRQISKQGLSGAVVDLSKTSDHIQFSVEELKNLFTLHESSHCVTHDLLDCECTGENHTGDSLEKLPVSRNCQLGPHQQKSDSLKPLSMSQLKQWRHFPGDHLNLTDPFLERIRENVSFFFQNITNQTTAI", "length": 889, "header": "tr|A0ABI0NJU3-1|A0ABI0P3K7_BOVIN Computationally mapped isoform of Fibrinogen silencer binding protein OS=Bos taurus OX=9913 GN=FSBP PE=4 SV=1 CANONICAL=A0ABI0P3K7-1" }, "locus": { "chromosome": "14", "start_pos": 69976195, "end_pos": 69858952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148993.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148993.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104504.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104504.1" } ] } }, { "isoform_ac": "A0ABI0NMV1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7/entry#A0ABI0NMV1-1", "sequence": { "sequence": "MDRGAWWATVHGVAKSRTGLSDFTFFLMELEGGKQKQQGRLILLNMRRSAAPSQLQGNPFKKPKFISPARSHPSPNEEVAKLNSDIKLFEVAANKNNFLQPQNDPRTCNFNLPTKECAKGINHGDNYREKYCLEASTKTTLDLHHTVHSAPKEITVSKGQEEKPDSLVKYFSVVWCKASKKKHKKWEGDGVLIVKGKSFTLKDLEGKDIGRGTGYKLKELEKIEEGQTMMIGGKEIEVMGIISPDDFNSGRCFQFGGGCSAILSSSQAAKKCFSNPFKSVCKLSSKENKQNSFQSCKPRHDPYAPNSLVMLRPDKNHQWLFNKNCFPVVDVVIDPHLVYYLRPHQKEGITFLYECVMGMRVNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPIVKKTLIVTPGSLVNNWKKEFQKWLGIERIKIFTVDQDHKVEEFTKSPFYSVLIISYEMLLRSLDQIKNVKFDLLICDEGHRLKNSTIKTTTALISLSCEKRIILTGTPVQNDLQEFFTLIDFVNPGILGSLSAYRKIYEEPIIISRQPSASEEERELGEQRAAELTCLTGLFILRRTQEVINQYLPPKIENVVFCRPGALQIALYRKLLNSQAVRFCLQGLLENTSHLICIGALKKLCNHPCLLFGSIKEKESNSTWDESEERNLYEGLMNVFPADYNPIMFTEEESGKLQVLSKLLAVIRELRPAEKVVLVSNYTRTLDILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSKYSSDFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKHPVHIYRLLTTGTIEEKIYQRQISKQGLSGAVVDLSKTSDHIQFSVEELKNLFTLHESSHCVTHDLLDCECTGENHTGDSLEKLPVSRNCQLGPHQQKSDSLKPLSMSQLKQWRHFPGDHLNLTDPFLERIRENVSFFFQNITNQTTAI", "length": 954, "header": "tr|A0ABI0NMV1-1|A0ABI0P3K7_BOVIN Computationally mapped isoform of Fibrinogen silencer binding protein OS=Bos taurus OX=9913 GN=FSBP PE=4 SV=1 CANONICAL=A0ABI0P3K7-1" }, "locus": { "chromosome": "14", "start_pos": 69976195, "end_pos": 69858952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136537.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136537.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106857.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106857.1" } ] } }, { "isoform_ac": "A0ABI0P3K7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7/entry#A0ABI0P3K7-1", "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLKLVKPYVKILEEHTNKHSVIVEKNRCWDIIAVNYNAIGVDRPPRTAQGLRTLYKRLKEYAKQELLQQKETQSDFKSNISEPTKKVMEMIPQISSFCLVRDRNHIQSANLDEEAQAGTSSLQVMLDRHPVAITVEVKQEEDIKPPLPLVLNSQQSDTLEQREEQELVRVMERSLSPSLSSVDMRMTSSPSSIPRRDDFFRHESGENFRSQLGYDPQILQMLKEEHQIILENQKSFGLYVQEKRDGLKRRQQLEEELLRAKIEVEKLKAIRLRHDLPEYNSL", "length": 299, "header": "tr|A0ABI0P3K7-1|A0ABI0P3K7_BOVIN Isoform 1 of Fibrinogen silencer binding protein OS=Bos taurus OX=9913 GN=FSBP PE=4 SV=1 CANONICAL=A0ABI0P3K7-1" }, "locus": { "chromosome": "14", "start_pos": 69910869, "end_pos": 69906195, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147042.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147042.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105334.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105334.1" } ] } }, { "isoform_ac": "A0ABI0P814-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7/entry#A0ABI0P814-1", "sequence": { "sequence": "MLWRWGCRCLLRVVLVPGPSLPSDSRRLILLNMRRSAAPSQLQGNPFKKPKFISPARSHPSPNEEVAKLNSDIKLFEVAANKNNFLQPQNDPRTCNFNLPTKECAKGINHGDNYREKYCLEASTKTTLDLHHTVHSAPKEITVSKGQEEKPDSLVKYFSVVWCKASKKKHKKWEGDGVLIVKGKSFTLKDLEGKDIGRGTGYKLKELEKIEEGQTMMIGGKEIEVMGIISPDDFNSGRCFQFGGGCSAILSSSQAAKKCFSNPFKSVCKLSSKENKQNSFQSCKPRHDPYAPNSLVMLRPDKNHQWLFNKNCFPVVDVVIDPHLVYYLRPHQKEGITFLYECVMGMRVNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPIVKKTLIVTPGSLVNNWKKEFQKWLGIERIKIFTVDQDHKVEEFTKSPFYSVLIISYEMLLRSLDQIKNVKFDLLICDEGHRLKNSTIKTTTALISLSCEKRIILTGTPVQNDLQEFFTLIDFVNPGILGSLSAYRKIYEEPIIISRQPSASEEERELGEQRAAELTCLTGLFILRRTQEVINQYLPPKIENVVFCRPGALQIALYRKLLNSQAVRFCLQGLLENTSHLICIGALKKLCNHPCLLFGSIKEKESNSTWDESEERNLYEGLMNVFPADYNPIMFTEEESGKLQVLSKLLAVIRELRPAEKVVLVSNYTRTLDILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSKYSSDFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKHPVHIYRLLTTGTIEEKIYQRQISKQGLSGAVVDLSKTSDHIQFSVEELKNLFTLHESSHCVTHDLLDCECTGENHTGDSLEKLPVSRNCQLGPHQQKSDSLKPLSMSQLKQWRHFPGDHLNLTDPFLERIRENVSFFFQNITNQTTAI", "length": 941, "header": "tr|A0ABI0P814-1|A0ABI0P814_BOVIN Computationally mapped isoform of DNA repair and recombination protein RAD54B OS=Bos taurus OX=9913 GN=FSBP PE=3 SV=1 CANONICAL=A0ABI0P3K7-1" }, "locus": { "chromosome": "14", "start_pos": 69976195, "end_pos": 69858299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148989.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148989.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107469.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107469.1" } ] } }, { "isoform_ac": "E1BJC3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7/entry#E1BJC3-1", "sequence": { "sequence": "MRRSAAPSQLQGNPFKKPKFISPARSHPSPNEEVAKLNSDIKLFEVAANKNNFLQPQNDPRTCNFNLPTKECAKGINHGDNYREKYCLEASTKTTLDLHHTVQTWMRKHRLVPVHYR", "length": 117, "header": "tr|E1BJC3-1|A0ABI0P3K7_BOVIN Computationally mapped isoform of Fibrinogen silencer binding protein OS=Bos taurus OX=9913 GN=FSBP PE=4 SV=2 CANONICAL=A0ABI0P3K7-1" }, "locus": { "chromosome": "14", "start_pos": 69910393, "end_pos": 69875365, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034843.4", "url": "https://www.ensembl.org/id/ENSBTAT00000034843.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034727.2", "url": "https://www.ensembl.org/id/ENSBTAP00000034727.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100848732", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100848732", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NUT3-1", "protein_name": "Fibrinogen silencer binding protein", "gene_name": "FSBP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLKLVKPYVKILEEHTNKHSVIVEKNKCWDIIADNYNAIGVDRPPRTAQGLRTLYKRLKEYAKQELLQQKETHSDCKSSISEPTKKVVEMIPQISNVCLRDRSGAQSASIDKETIAGTSSPQAVLDHHPATVMMKLQLEEDVKPPPSLIIDSQPSENVEQEEEHQLVHVMERSPSTSVSSVDMRVMMSPSPVPRRDEFFRLEVGERFRPMCGYDPQMLQMLKEEHQIMLENQRKIGLYVQEKRDGLKRKQQLEEELLRTKIKVEKLKAIRLRRDLPEYSII", "length": 298 }, "evidence": [ { "id": "A0ABI0P3K7", "url": "https://omabrowser.org/oma/group/A0ABI0P3K7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A287AE18-1", "protein_name": "DNA repair and recombination protein RAD54B", "gene_name": "RAD54B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRSAAPSQLQGNPLKKPRFIPPARSDPGLNEEKKLNSDVKLFEVPANKNAFLQSQNDPRICSFNLPPEESAREINREDNYREKYHLEASAKTTLDPHHTAHSAPKEVMVSNGQEEEPDSLVKYFSVVWCKASKKKHKKWEGDAVLIVKGKSFALKDLEGKDIGRGIGYKFKELEKIEEGQTMMIGGKEIEVMGVISPDDFSSGRCFQLGLSGALNSSQTPKKCTSNPFKSVCKLSSKENRQNGFQNCKPRHDPYAPNSLVMLRPDNNHQWMFNKNHFPIVDVVIDPHLVYHLRPHQREGIIFLYECVMGMRVNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKTLIVTPGSLVNNWRKEFQKWLGSERIKIFTVDPDHKVEEFTKSPLYSVLIISYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALFSLPCEKRIILTGTPVQNDLQEFFSLIDFVNPGILGSLSCYRKIYEEPIITSRQPSASQEEKELGERRACELTCLTGLFILRRTQEVINKYLPPKIENVVFCRPGALQIELYRKLLNSQAVRFCLQGLMENSSHLICIGALKKLCNHPCLLFSSVKEKECSSAWDENEERRLYEDLLKVFPPDYNPLMFAEEESGKLQVLSKLLAVIHELRPAEKVVLVSNYTQTLNILQEVCRRHGYGCTRLDGQTPISQRQQIVDGFNSKYSSDFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKHPVHIYRLLTTGTIEEKIYQRQISKQDLSGAVVDLTKTSDHIQFSVEELKNLFTLHENSHCVTHDLLDCECTGENHPGDSLEKFPLSRTCQLGPHQQKSNSLKPLSMSQLKQWKHFSGDHLNLSDPFLERIRGNVSFFFQNITNQTTAT", "length": 906 }, "evidence": [ { "id": "A0ABI0P3K7", "url": "https://omabrowser.org/oma/group/A0ABI0P3K7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3L7I3P3-1", "protein_name": "Fibrinogen silencer-binding protein", "gene_name": "Fsbp", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLSLVKPYVKILEEHTNKNSVIVEKNRCWDVIAVNYNAIGVDRPPRTAQGLRSLYKRLKEYAKQELLQQKEAQSDFKSSISEPTKKVMEMIPQISSFCLIRDRNHIQSANLDEAAQAGTSSLQVMVDHHPVAITVEVKQEEDIKSSPPLFPNPQHNDTSEQREEHELVHVMEEPLSPSLSSVDMRMTSSPSSIPRRDDFFHHESGEHFRSLLRYDPQILQMLKEEHQIILENQKNFGLYVQEKRDGLRRRQQLEEELLRAKIEVEKLKATRLRHDLTEYSSL", "length": 299 }, "evidence": [ { "id": "A0ABI0P3K7", "url": "https://omabrowser.org/oma/group/A0ABI0P3K7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95073-1", "protein_name": "Fibrinogen silencer-binding protein", "gene_name": "FSBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLKLVKPYVKILEEHTNKHSVIVEKNRCWDIIAVNYNAIGVDRPPRTAQGLRTLYKRLKEYAKQELLQQKETQSDFKSNISEPTKKVMEMIPQISSFCLVRDRNHIQSANLDEEAQAGTSSLQVMLDHHPVAITVEVKQEEDIKPPPPLVLNSQQSDTLEQREEHELVHVMERSLSPSLSSVDMRMTSSPSSIPRRDDFFRHESGEHFRSLLGYDPQILQMLKEEHQIILENQKNFGLYVQEKRDGLKRRQQLEEELLRAKIEVEKLKAIRLRHDLPEYNSL", "length": 299 }, "evidence": [ { "id": "A0ABI0P3K7", "url": "https://omabrowser.org/oma/group/A0ABI0P3K7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BKE5-1", "protein_name": "Fibrinogen silencer-binding protein", "gene_name": "Fsbp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLNLVKPYVKILEEHTNKNSVIVEKNRCWDVIAVNYNAIGVDRPPRTAQGLRSLYKRLKEYAKQELLQQKEAQSEFKSSVSEPTKQVMEMIPQIASFGLIRDRSHIQSANLDETAQAGTSSLQVMVDHHPVAITVEVKQEEDIKPSPPLVSNPQLSDTLEQREEHELMHVVEGSESPSLSSVDMRMTSSPSSVPRRDEIFHQESGEHFRSLLRCDPQVLQMLKEEHQIILENQKNFGLYVQEKRDGLRRRQRLEEELLRAKIEVEKLKATRLRRDLPEYSSL", "length": 299 }, "evidence": [ { "id": "A0ABI0P3K7", "url": "https://omabrowser.org/oma/group/A0ABI0P3K7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", "F1N2W9-1", "E1BB03-1", "E1BMP7-1", "A0JND9-1", "E1BAS6-1", "A0AAA9RXM7-1", "Q59HJ6-1", "Q2KJ94-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "A0AAF6Z0E4-1", "G3MZH7-1", "F1MKC7-1", "A0AAA9S7V9-1", "A0AAF6YME1-1", "F1MFR1-1", "Q3T084-1", "E1B7X9-1", "A0ABI0P204-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LG16", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] } ] }, { "uniprot_ac": "A0A3Q1LQC3", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] } ] }, { "uniprot_ac": "A0A3Q1LSH0", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] } ] }, { "uniprot_ac": "A0A3Q1LT80", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] } ] }, { "uniprot_ac": "A0A3Q1LTL4", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] } ] }, { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1LXD0", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] } ] }, { "uniprot_ac": "A0A3Q1M0A4", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A3Q1M0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0A4" } ] } ] }, { "uniprot_ac": "A0A3Q1M155", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] } ] }, { "uniprot_ac": "A0A3Q1M493", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": 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phosphate + H(+).", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] } ] }, { "uniprot_ac": "A0AAA9RXM7", "gene_name": "HLTF", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXM7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXM7", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] } ] }, { "uniprot_ac": "A0AAA9SX42", "gene_name": "TDRD12", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SX42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9SX42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX42" } ] } ] }, { "uniprot_ac": "A0AAA9T2L7", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0AAA9T2L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2L7" } ] }, { "ec_number": "5.6.2.3", "activity": "", 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"url": "https://www.uniprot.org/uniprotkb/A4FUD9" } ] } ] }, { "uniprot_ac": "A4K436", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A4K436", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4K436" } ] } ] }, { "uniprot_ac": "A5D7C1", "gene_name": "DDX52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] } ] }, { "uniprot_ac": "A5PJA1", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": 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"evidence": [ { "id": "A7Z019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7Z019" } ] } ] }, { "uniprot_ac": "E1B7X9", "gene_name": "SMARCAD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1B7X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7X9" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B9N7", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "O18956", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] } ] }, { "uniprot_ac": "P09487", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.9.1.1", "activity": "N-phosphocreatine + H2O = creatine + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] } ] }, { "uniprot_ac": "P19120", "gene_name": "HSPA8", "activity": [ { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62739" } ] } ] }, { "uniprot_ac": "P63258", "gene_name": "ACTG1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P63258" } ] } ] }, { "uniprot_ac": "P68138", "gene_name": "ACTA1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68138" } ] } ] }, { "uniprot_ac": "Q05B79", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBV2" } ] } ] }, { "uniprot_ac": "Q3ZC07", "gene_name": "ACTC1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q3ZC07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZC07" } ] } ] }, { "uniprot_ac": "Q3ZC91", "gene_name": "SMPDL3A", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "Q3ZC91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZC91" } ] }, { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "Q3ZC91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZC91" } ] } ] }, { "uniprot_ac": "Q3ZCH0", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q3ZCH0", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/Q59HJ6" } ] } ] }, { "uniprot_ac": "Q5E9B5", "gene_name": "ACTG2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q5E9B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9B5" } ] } ] }, { "uniprot_ac": "Q5E9H5", "gene_name": "BCS1L", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5E9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9H5" } ] } ] }, { "uniprot_ac": "Q5E9M9", "gene_name": "RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q5E9M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9M9" } ] } ] }, { "uniprot_ac": "Q5E9N5", "gene_name": "CLPB", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5E9N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9N5" } ] } ] }, { "uniprot_ac": "Q5W5U4", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5W5U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5W5U4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5W5U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5W5U4" } ] } ] }, { "uniprot_ac": "Q76LV2", "gene_name": "HSP90AA1", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q76LV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q76LV2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "Q76LV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q76LV2" } ] } ] }, { "uniprot_ac": "Q95M18", "gene_name": "HSP90B1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q95M18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95M18" } ] } ] }, { "uniprot_ac": "Q9TTA5", "gene_name": "SMARCAL1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q9TTA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9TTA5" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "Q9TTA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9TTA5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K7" }, { "id": "PF13873", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb/SANT-like DNA-binding", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 85, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 96, "end_pos": 98 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P0K6-1", "uniprot_ac": "A0ABI0P0K6", "uniprot_id": "A0ABI0P0K6_BOVIN", "mass": { "chemical_mass": 71881.0, "monoisotopic_mass": 71881.0 }, "refseq": { "ac": "NP_001178129", "name": "leucine zipper putative tumor suppressor 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178129" }, "gene_names": [ { "name": "LZTS3", "type": "recommended", "evidence": [ { "id": "A0ABI0P0K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0K6" } ] }, { "name": "LZTS3", "type": "synonym", "evidence": [ { "id": "NP_001178129", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178129" } ] }, { "name": "PROSAPIP1", "type": "synonym", "evidence": [ { "id": "NP_001178129", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178129" } ] } ], "protein_names": [ { "name": "Leucine zipper tumor suppressor family member 3", "type": "synonym", "evidence": [ { "id": "A0ABI0P0K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0K6/entry#names_and_taxonomy" } ] }, { "name": "leucine zipper putative tumor suppressor 3", "type": "synonym", "evidence": [ { "id": "NP_001178129", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178129" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0K6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0K6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LZTS3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0K6", "locus": { "chromosome": "13", "start_pos": 52039191, "end_pos": 52028263, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020454", "url": "https://www.ensembl.org/id/ENSBTAG00000020454" } ] } } ], "crossref": [ { "id": "ENSBTAG00000020454", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020454", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "512397", "url": "https://www.ncbi.nlm.nih.gov/gene/512397", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR045329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512397", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512397", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BNL7", "url": "https://www.orthodb.org/?gene=E1BNL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19354", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19354", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19354:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19354:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178129", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178129", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5I4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5I4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MJ16", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJ16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MJ16-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJ16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0K6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0K6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0K6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNL7", "url": "https://www.uniprot.org/uniprotkb/E1BNL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BNL7-1", "url": "https://www.uniprot.org/uniprotkb/E1BNL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHTQEFAMKSVGTRTGGGGNQGSFPGPRSSGVSRERPGRYPSEDKALANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPSHPPKLLAASGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPGGLKGGLDKSRTMTPAGGGGSGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTASYGSGSGGGSSGGGSGYQDLATSDSGRASSKSGSSSSMGRPGHLGSGEGGGGGLPFTACSPPSPSALIQELEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRMEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASLELGEGELPSACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVAAAASLVSLDGEADTGGESGTRALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAWTPSRLERIESTEI", "length": 672, "header": "tr|A0ABI0P0K6-1|A0ABI0P0K6_BOVIN Isoform 1 of Leucine zipper tumor suppressor family member 3 OS=Bos taurus OX=9913 GN=LZTS3 PE=4 SV=1 CANONICAL=A0ABI0P0K6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M5I4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0K6/entry#A0A3Q1M5I4-1", "sequence": { "sequence": "MAPADRASEGPRLEAPSAPHPLGECPPGLVMAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHTQEFAMKSVGTRTGGGGNQGSFPGPRSSGVSRERPGRYPSEDKALANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPSHPPKLLAASGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPGGLKGGLDKSRTMTPAGGGGSGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTASYGSGSGGGSSGGGSGYQDLATSDSGRASSKSGSSSSMGRPGHLGSGEGGGGGLPFTACSPPSPSALIQELEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRMEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASLELGEGELPSACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVAAAASLVSLDGEADTGGESGTRALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAWTPSRLERIESTEI", "length": 702, "header": "tr|A0A3Q1M5I4-1|A0ABI0P0K6_BOVIN Computationally mapped isoform of Leucine zipper tumor suppressor family member 3 OS=Bos taurus OX=9913 GN=LZTS3 PE=4 SV=1 CANONICAL=A0ABI0P0K6-1" }, "locus": { "chromosome": "13", "start_pos": 52036244, "end_pos": 52032874, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077939.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077939.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065561.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065561.2" } ] } }, { "isoform_ac": "A0A3Q1MJ16-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0K6/entry#A0A3Q1MJ16-1", "sequence": { "sequence": "MAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHTQEFAMKSVGTRTGGGGNQGSFPGPRSSGVSRERPGRYPSEDKALANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPSHPPKLLAASGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPGGLKGGLDKSRTMTPAGGGGSGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTASYGSGSGGGSSGGGSGYQDLATSDSGRASSKSGSSSSMGRPGHLGSGEGGGGGLPFTACSPPSPSALIQELEERLWEKEQEVAALRRSLEQSEAAVAQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRMEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASLELGEGELPSACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVAAAASLVSLDGEADTGGESGTRALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAWTPSRLERIESTEI", "length": 626, "header": "tr|A0A3Q1MJ16-1|A0ABI0P0K6_BOVIN Computationally mapped isoform of Leucine zipper tumor suppressor family member 3 OS=Bos taurus OX=9913 GN=LZTS3 PE=4 SV=1 CANONICAL=A0ABI0P0K6-1" }, "locus": { "chromosome": "13", "start_pos": 52036244, "end_pos": 52033559, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075901.3", "url": "https://www.ensembl.org/id/ENSBTAT00000075901.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070748.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070748.2" } ] } }, { "isoform_ac": "A0ABI0P0K6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0K6/entry#A0ABI0P0K6-1", "sequence": { "sequence": "MAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHTQEFAMKSVGTRTGGGGNQGSFPGPRSSGVSRERPGRYPSEDKALANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPSHPPKLLAASGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPGGLKGGLDKSRTMTPAGGGGSGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTASYGSGSGGGSSGGGSGYQDLATSDSGRASSKSGSSSSMGRPGHLGSGEGGGGGLPFTACSPPSPSALIQELEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRMEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASLELGEGELPSACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVAAAASLVSLDGEADTGGESGTRALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAWTPSRLERIESTEI", "length": 672, "header": "tr|A0ABI0P0K6-1|A0ABI0P0K6_BOVIN Isoform 1 of Leucine zipper tumor suppressor family member 3 OS=Bos taurus OX=9913 GN=LZTS3 PE=4 SV=1 CANONICAL=A0ABI0P0K6-1" }, "locus": { "chromosome": "13", "start_pos": 52036244, "end_pos": 52033559, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137884.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137884.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104021.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104021.1" } ] } }, { "isoform_ac": "E1BNL7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0K6/entry#E1BNL7-1", "sequence": { "sequence": "MRAAQAATAHPTPNTSVLSRSRCPGVPGTRQLCECPPGLVMAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHTQEFAMKSVGTRTGGGGNQGSFPGPRSSGVSRERPGRYPSEDKALANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPPQYREPSHPPKLLAASGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNGTPEGRQGPGGLKGGLDKSRTMTPAGGGGSGLSDSGRNSLTSLPTYSSSYSQHLAPLSASTSHINRIGTASYGSGSGGGSSGGGSGYQDLATSDSGRASSKSGSSSSMGRPGHLGSGEGGGGGLPFTACSPPSPSALIQELEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRMEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASLELGEGELPSACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVAAAASLVSLDGEADTGGESGTRALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHGEEKKAWTPSRLERIESTEI", "length": 712, "header": "tr|E1BNL7-1|A0ABI0P0K6_BOVIN Computationally mapped isoform of Leucine zipper tumor suppressor family member 3 OS=Bos taurus OX=9913 GN=LZTS3 PE=4 SV=2 CANONICAL=A0ABI0P0K6-1" }, "locus": { "chromosome": "13", "start_pos": 52036244, "end_pos": 52032658, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027256.5", "url": "https://www.ensembl.org/id/ENSBTAT00000027256.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027256.4", "url": "https://www.ensembl.org/id/ENSBTAP00000027256.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 649, "start_aa": "Thr", "end_pos": 649, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr649", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:512397", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512397", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0K6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0K6" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0K6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0K6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of dendritic spine morphogenesis", "id": "GO:0061001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061001", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0K6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0K6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 649 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 182, "end_pos": 184 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P1Y8-1", "uniprot_ac": "A0ABI0P1Y8", "uniprot_id": "A0ABI0P1Y8_BOVIN", "mass": { "chemical_mass": 37596.0, "monoisotopic_mass": 37596.0 }, "refseq": {}, "gene_names": [ { "name": "MGLL", "type": "recommended", "evidence": [ { "id": "A0ABI0P1Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8" } ] } ], "protein_names": [ { "name": "Monoglyceride lipase", "type": "recommended", "evidence": [ { "id": "A0ABI0P1Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.23", "type": "synonym", "evidence": [ { "id": "A0ABI0P1Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8/entry#names_and_taxonomy" } ] }, { "name": "Monoacylglycerol lipase", "type": "synonym", "evidence": [ { "id": "A0ABI0P1Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.", "evidence": [ { "database": "UniProtKB", "id": "F1MC02", "url": "https://www.uniprot.org/uniprotkb/F1MC02#function" }, { "database": "UniProtKB", "id": "ARBA00058731", "url": "https://www.uniprot.org/uniprotkb/ARBA00058731#function" }, { "database": "UniProtKB", "id": "A0ABI0P1Y8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8#function" }, { "database": "UniProtKB", "id": "A0A3Q1N439", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N439#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MGLL", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8", "locus": { "chromosome": "22", "start_pos": 59826846, "end_pos": 59737137, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018248", "url": "https://www.ensembl.org/id/ENSBTAG00000018248" } ] } } ], "crossref": [ { "id": "ENSBTAG00000018248", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018248", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "505290", "url": "https://www.ncbi.nlm.nih.gov/gene/505290", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MFP1", "url": "https://www.orthodb.org/?gene=A0A3Q1MFP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N439", "url": "https://www.orthodb.org/?gene=A0A3Q1N439", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MC02", "url": "https://www.orthodb.org/?gene=F1MC02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12146", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12146", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1482883", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482883", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-426048", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-426048", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "26132", "url": "https://www.rhea-db.org/rhea/26132", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34019", "url": "https://www.rhea-db.org/rhea/34019", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44688", "url": "https://www.rhea-db.org/rhea/44688", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MFP1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MFP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N439", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N439", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N439-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N439-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1Y8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MC02", "url": "https://www.uniprot.org/uniprotkb/F1MC02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MC02-1", "url": "https://www.uniprot.org/uniprotkb/F1MC02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQTAPEDPFRMPEERPPRLTPQNVPYQDLPHLVNADGQHLFCRYWRPLSAPRALVFVSHGAGEHCGRYDELAQMLVGLGLLVFAHDHVGHGQSEGERMVVSDFHVFIRDVLQHVDAVQKDYPGLPVFLLGHSMGGAICILTAAERPGHFSGMVLISPLVVANPESATLFKDPPKILEEVFQLTGRTIVSWMPASLWVFAAKVLNLVLPNMSLGRIDSSVLSRNKTEVDIYNTDPLVCRAGLKVCFGNQLLNAVSRVERALPKLTLPFLLLQGSADRLCNSRGAYLLMESAKSQDKTLKIYEGAYHILHKELPEVTSSVFREINTWVSQRTAVEGMGCPP", "length": 339, "header": "tr|A0ABI0P1Y8-1|A0ABI0P1Y8_BOVIN Isoform 1 of Monoglyceride lipase OS=Bos taurus OX=9913 GN=MGLL PE=3 SV=1 CANONICAL=A0ABI0P1Y8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MFP1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8/entry#A0A3Q1MFP1-1", "sequence": { "sequence": "MQTAPEDPFRMPEERPPRLTPQNVPYQDLPHLVNADGQHLFCRYWRPLSAPRALVFVSHGAGEHCGRYDELAQMLVGLGLLVFAHDHVGHGQSEGERMVVSDFHVFIRDVLQHVDAVQKDYPGLPVFLLGHSMGGAICILTAAERPGHFSGMVLISPLVVANPESATLFKVDIYNTDPLVCRAGLKVCFGNQLLNAVSRVERALPKLTLPFLLLQGSADRLCNSRGAYLLMESAKSQDKTLKIYEGAYHILHKELPEVTSSVFREINTWVSQRTAVEGMGCPP", "length": 283, "header": "tr|A0A3Q1MFP1-1|A0ABI0P1Y8_BOVIN Computationally mapped isoform of Monoglyceride lipase OS=Bos taurus OX=9913 GN=MGLL PE=3 SV=2 CANONICAL=A0ABI0P1Y8-1" }, "locus": { "chromosome": "22", "start_pos": 59824837, "end_pos": 59737968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080050.3", "url": "https://www.ensembl.org/id/ENSBTAT00000080050.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069967.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069967.2" } ] } }, { "isoform_ac": "A0A3Q1N439-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8/entry#A0A3Q1N439-1", "sequence": { "sequence": "MQTAPEDPFRMPEERPPRLTPQNVPYQDLPHLVNADGQHLFCRYWRPLSAPRALVFVSHGAGEHCGRYDELAQMLVGLGLLVFAHDHVGHGQSEGERMVVSDFHVFIRDVLQHVDAVQKDYPGLPVFLLGHSMGGAICILTAAERPGHFSGMVLISPLVVANPESATLFKVFAAKVLNLVLPNMSLGRIDSSVLSRNKTEVDIYNTDPLVCRAGLKVCFGNQLLNAVSRVERALPKLTLPFLLLQGSADRLCNSRGAYLLMESAKSQDKTLKIYEGAYHILHKELPEVTSSVFREINTWVSQRTAVEGMGCPP", "length": 313, "header": "tr|A0A3Q1N439-1|A0ABI0P1Y8_BOVIN Computationally mapped isoform of Monoglyceride lipase OS=Bos taurus OX=9913 GN=MGLL PE=3 SV=2 CANONICAL=A0ABI0P1Y8-1" }, "locus": { "chromosome": "22", "start_pos": 59824837, "end_pos": 59737968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072869.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072869.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064451.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064451.2" } ] } }, { "isoform_ac": "A0ABI0P1Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8/entry#A0ABI0P1Y8-1", "sequence": { "sequence": "MQTAPEDPFRMPEERPPRLTPQNVPYQDLPHLVNADGQHLFCRYWRPLSAPRALVFVSHGAGEHCGRYDELAQMLVGLGLLVFAHDHVGHGQSEGERMVVSDFHVFIRDVLQHVDAVQKDYPGLPVFLLGHSMGGAICILTAAERPGHFSGMVLISPLVVANPESATLFKDPPKILEEVFQLTGRTIVSWMPASLWVFAAKVLNLVLPNMSLGRIDSSVLSRNKTEVDIYNTDPLVCRAGLKVCFGNQLLNAVSRVERALPKLTLPFLLLQGSADRLCNSRGAYLLMESAKSQDKTLKIYEGAYHILHKELPEVTSSVFREINTWVSQRTAVEGMGCPP", "length": 339, "header": "tr|A0ABI0P1Y8-1|A0ABI0P1Y8_BOVIN Isoform 1 of Monoglyceride lipase OS=Bos taurus OX=9913 GN=MGLL PE=3 SV=1 CANONICAL=A0ABI0P1Y8-1" }, "locus": { "chromosome": "22", "start_pos": 59824837, "end_pos": 59737968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143220.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143220.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105314.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105314.1" } ] } }, { "isoform_ac": "F1MC02-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8/entry#F1MC02-1", "sequence": { "sequence": "MPEERPPRLTPQNVPYQDLPHLVNADGQHLFCRALVFVSHGAGEHCGRYDELAQMLVGLGLLVFAHDHVGHGQSEGERMVVSDFHVFIRDVLQHVDAVQKDYPGLPVFLLGHSMGGAICILTAAERPGHFSGMVLISPLVVANPESATLFKVFAAKVLNLVLPNMSLGRIDSSVLSRNKTEVDIYNTDPLVCRAGLKVCFGNQLLNAVSRVERALPKLTLPFLLLQGSADRLCNSRGAYLLMESAKSQDKTLKIYEGAYHILHKELPEVTSSVFREINTWVSQRTAVEGMGCPP", "length": 294, "header": "tr|F1MC02-1|A0ABI0P1Y8_BOVIN Computationally mapped isoform of Monoglyceride lipase OS=Bos taurus OX=9913 GN=MGLL PE=3 SV=5 CANONICAL=A0ABI0P1Y8-1" }, "locus": { "chromosome": "22", "start_pos": 59824837, "end_pos": 59738463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024289.8", "url": "https://www.ensembl.org/id/ENSBTAT00000024289.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024289.8", "url": "https://www.ensembl.org/id/ENSBTAP00000024289.8" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-1482883", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482883", "resource": "Reactome", "description": "Acyl chain remodeling of DAG and TAG" }, { "id": "R-BTA-426048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-426048", "resource": "Reactome", "description": "Arachidonate production from DAG" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8" } ], "pmid": "" }, { "name": "acylglycerol catabolic process", "id": "GO:0046464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046464", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "26132", "name": "", "equation": "2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1MLE6-1", "Q5EA42-1", "P16386-1", "Q08DW9-1", "Q1JPD2-1", "Q1LZ86-1", "F1MUV1-1", "A0ABI0P1Y8-1", "A0AAA9TLW2-1" ], "evidence": [ { "id": "26132", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/26132" } ] }, { "id": "34019", "name": "", "equation": "a 1-acylglycerol + H2O = glycerol + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1Y8-1", "Q1LZ86-1" ], "evidence": [ { "id": "34019", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34019" } ] }, { "id": "44688", "name": "", "equation": "a 2-acylglycerol + H2O = glycerol + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1Y8-1", "Q1LZ86-1" ], "evidence": [ { "id": "44688", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44688" } ] }, { "id": "R-BTA-1482543", "name": "2-MAG is hydrolyzed to fatty acid and glycerol by MGLL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-1500593" ], "enzyme_list": [ "A0ABI0P1Y8-1" ], "evidence": [ { "id": "R-BTA-1482543", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482543" } ] }, { "id": "R-BTA-426043", "name": "2-AG hydrolysis to arachidonate by MAGL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-ALL-426030" ], "output_participant_list": [ "R-ALL-422506" ], "enzyme_list": [ "A0ABI0P1Y8-1" ], "evidence": [ { "id": "R-BTA-426043", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-426043" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1500593", "participant_name": "fatty acid [endoplasmic reticulum membrane]", "crossref": [ { "id": "35366", "database": "ChEBI", "url": "" }, { "id": "C00162", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-422506", "participant_name": "AA [plasma membrane]", "crossref": [ { "id": "ZINC000004474696", "database": "ZINC", "url": "" }, { "id": "32395", "database": "ChEBI", "url": "" }, { "id": "C00219", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-426030", "participant_name": "2AG [plasma membrane]", "crossref": [ { "id": "52392", "database": "ChEBI", "url": "" }, { "id": "729", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000004654969", "database": "ZINC", "url": "" }, { "id": "HMDB0004666", "database": "HMDB Metabolite", "url": "" }, { "id": "C13856", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MLE6", "gene_name": "LIPE", "activity": [ { "ec_number": "3.1.1.23", "activity": "Hydrolyzes glycerol monoesters of long-chain fatty acids.", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] }, { "ec_number": "3.1.1.79", "activity": "a monoacylglycerol + H2O = glycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] }, { "ec_number": "3.1.1.23", "activity": "", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] }, { "ec_number": "3.1.1.79", "activity": "", "evidence": [ { "id": "A0A3Q1MLE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLE6" } ] } ] }, { "uniprot_ac": "A0AAA9TLW2", "gene_name": "LOC513210", "activity": [ { "ec_number": "3.5.1.99", "activity": "N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + H2O = ethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate.", "evidence": [ { "id": "A0AAA9TLW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLW2" } ] }, { "ec_number": "3.5.1.99", "activity": "", "evidence": [ { "id": "A0AAA9TLW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLW2" } ] } ] }, { "uniprot_ac": "A0ABI0P1Y8", "gene_name": "MGLL", "activity": [ { "ec_number": "3.1.1.23", "activity": "Hydrolyzes glycerol monoesters of long-chain fatty acids.", "evidence": [ { "id": "A0ABI0P1Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8" } ] }, { "ec_number": "3.1.1.23", "activity": "", "evidence": [ { "id": "A0ABI0P1Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y8" } ] } ] }, { "uniprot_ac": "F1MUV1", "gene_name": "FAAH", "activity": [ { "ec_number": "3.5.1.99", "activity": "N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + H2O = ethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate.", "evidence": [ { "id": "F1MUV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUV1" } ] }, { "ec_number": "3.5.1.99", "activity": "", "evidence": [ { "id": "F1MUV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUV1" } ] } ] }, { "uniprot_ac": "P16386", "gene_name": "LIPE", "activity": [ { "ec_number": "3.1.1.23", "activity": "Hydrolyzes glycerol monoesters of long-chain fatty acids.", "evidence": [ { "id": "P16386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16386" } ] }, { "ec_number": 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"MSFQNQSSVLHKFKGILFSTMSSEELLNSLDSFDAREDDVFLVSYPKSGTHWIAEVIENIPNARITLTPPIELGDISKLEELKTYSERRVIPTHLSYDMLPMNIKQKQCKIIYIIRNPKDTAVSLFHYYRDNPNLPSIETWHEFLELFLRGDVVYGSWFDHILSWEEHKNAKNILIIFYEEMKKDPSKNIKKITTFLGLNVSDSEINKIAWKTSFSEMKNNTAEENCDPNHTICALTSNRKLVFRKGAVGDWINYFTSKQKRVFDELFTEKMKHSELAGHFRDYS", "length": 285 }, "evidence": [ { "id": "A0ABI0P531", "url": "https://omabrowser.org/oma/group/A0ABI0P531/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sulfotransferase activity", "id": "GO:0008146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008146", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P531", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P531" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sulfation", "id": "GO:0051923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051923", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P531", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P531" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P531", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P531" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "70607", "name": "", "equation": "4-ethylphenol + 3'-phosphoadenylyl sulfate = 4-ethylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P443-1", "uniprot_ac": "A0ABI0P443", "uniprot_id": "A0ABI0P443_BOVIN", "mass": { "chemical_mass": 41244.0, "monoisotopic_mass": 41244.0 }, "refseq": { "ac": "XP_005214760", "name": "serine/threonine-protein kinase Sgk2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214760" }, "gene_names": [ { "name": "SGK2", "type": "recommended", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "name": "SGK2", "type": "synonym", "evidence": [ { "id": "XP_005214760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214760" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase Sgk2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_005214760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214760" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P443", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SGK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443", "locus": { "chromosome": "13", "start_pos": 72175596, "end_pos": 72156148, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021033", "url": "https://www.ensembl.org/id/ENSBTAG00000021033" } ] } } ], "crossref": [ { "id": "ENSBTAG00000021033", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021033", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "517909", "url": "https://www.ncbi.nlm.nih.gov/gene/517909", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PRANGNI", "url": "https://omabrowser.org/oma/group/PRANGNI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M0A8", "url": "https://www.orthodb.org/?gene=A0A3Q1M0A8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MCB9", "url": "https://www.orthodb.org/?gene=A0A3Q1MCB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MZF7", "url": "https://www.orthodb.org/?gene=F1MZF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24351", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24351", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005214760", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214760", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M0A8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0A8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCB9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P443", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P443-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZF7", "url": "https://www.uniprot.org/uniprotkb/F1MZF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZF7-1", "url": "https://www.uniprot.org/uniprotkb/F1MZF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSSPAGTPSPQPLRANGNINLGPSANPNARPTDFDFLKVIGKGNYGKVLLAKHKSDGMFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLRIPGGRTVAACDLLQALLHKDQRQRLGSKTDFLEIKSHVFFSPINWDDLYHKRLTPPFNPNVAGPADLKHFDPEFTQEAVSKSIGCTPDTMASSSGASSAFLGFSYAPDDDAILDC", "length": 367, "header": "tr|A0ABI0P443-1|A0ABI0P443_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=SGK2 PE=3 SV=1 CANONICAL=A0ABI0P443-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M0A8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443/entry#A0A3Q1M0A8-1", "sequence": { "sequence": "MGLGLPEQPGQSVPDHCYSMDSSPAGTPSPQPLRANGNINLGPSANPNARPTDFDFLKVIGKGNYGKVLLAKHKSDGMFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLRIPGGRTVAACDLLQALLHKDQRQRLGSKTDFLEIKSHVFFSPINWDDLYHKRLTPPFNPNVAGPADLKHFDPEFTQEAVSKSIGCTPDTMASSSGASSAFLGFSYAPDDDAILDC", "length": 386, "header": "tr|A0A3Q1M0A8-1|A0ABI0P443_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=SGK2 PE=3 SV=3 CANONICAL=A0ABI0P443-1" }, "locus": { "chromosome": "13", "start_pos": 72172976, "end_pos": 72156460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084518.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084518.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066639.3", "url": "https://www.ensembl.org/id/ENSBTAP00000066639.3" } ] } }, { "isoform_ac": "A0A3Q1MCB9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443/entry#A0A3Q1MCB9-1", "sequence": { "sequence": "MDSSPAGTPSPQPLRANGNINLGPSANPNARPTDFDFLKVIGKGNYGKVLLAKHKSDGMFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEETTSTFCGTPEVTCANMGHTDLYFICESSNCPYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLRIPGGRTVAACDLLQALLHKDQRQRLGSKTDFLEIKSHVFFSPINWDDLYHKRLTPPFNPNVAGPADLKHFDPEFTQEAVSKSIGCTPDTMASSSGASSAFLGFSYAPDDDAILDC", "length": 388, "header": "tr|A0A3Q1MCB9-1|A0ABI0P443_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=SGK2 PE=3 SV=1 CANONICAL=A0ABI0P443-1" }, "locus": { "chromosome": "13", "start_pos": 72172976, "end_pos": 72157649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079037.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079037.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068466.1", "url": "https://www.ensembl.org/id/ENSBTAP00000068466.1" } ] } }, { "isoform_ac": "A0ABI0P443-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443/entry#A0ABI0P443-1", "sequence": { "sequence": "MDSSPAGTPSPQPLRANGNINLGPSANPNARPTDFDFLKVIGKGNYGKVLLAKHKSDGMFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLRIPGGRTVAACDLLQALLHKDQRQRLGSKTDFLEIKSHVFFSPINWDDLYHKRLTPPFNPNVAGPADLKHFDPEFTQEAVSKSIGCTPDTMASSSGASSAFLGFSYAPDDDAILDC", "length": 367, "header": "tr|A0ABI0P443-1|A0ABI0P443_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=SGK2 PE=3 SV=1 CANONICAL=A0ABI0P443-1" }, "locus": { "chromosome": "13", "start_pos": 72172976, "end_pos": 72157649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140678.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140678.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105860.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105860.1" } ] } }, { "isoform_ac": "F1MZF7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443/entry#F1MZF7-1", "sequence": { "sequence": "MDSSPAGTPSPQPLRANGNINLGPSANPNARPTDFDFLKVIGKGNYGKQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLRIPGGRTVAACDLLQALLHKDQRQRLGSKTDFLEIKSHVFFSPINWDDLYHKRLTPPFNPNVAGPADLKHFDPEFTQEAVSKSIGCTPDTMASSSGASSAFLGFSYAPDDDAILDC", "length": 339, "header": "tr|F1MZF7-1|A0ABI0P443_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=SGK2 PE=3 SV=2 CANONICAL=A0ABI0P443-1" }, "locus": { "chromosome": "13", "start_pos": 72172976, "end_pos": 72157649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028014.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028014.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028014.5", "url": "https://www.ensembl.org/id/ENSBTAP00000028014.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZNP7-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "SGK2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDRSRTSDSSAQPPTPTDNINLGPSANPNAKPTDFDFLKVIGKGSFGKVLLAKRKSDGTFYAVKVLHKKTILKKKEQNHIMAERNVLLKNVKHPFLVGLHYSFQTSEKLYFVLDYVNGGELFFHLQRERCFREPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGMEEEETTSTFCGTPEYLAPEVLKKQPYDRTVDWWCLGAVLYEMLFGLPPFYSRDVSQMYDNILHKQLQIQGSKTVAACDILHGLLHKDQKRRLGAKTDFLEIKNHVFFSPINWDDLYHKRITPPFNPNVAGPADLRHFDPEFTQEAISASITHTPDLAASSSSASDAFLGFSYAPTEEDF", "length": 364 }, "evidence": [ { "id": "A0ABI0P443", "url": "https://omabrowser.org/oma/group/A0ABI0P443/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P42818-1", "protein_name": "Serine/threonine-protein kinase AtPK1/AtPK6", "gene_name": "ATPK1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSSQRPVPNKIQKQQYLSISPSNSVLKDDVELEFSDVFGPLPEEANDIAYDEPAVVYSRSHSLVGPCSLDSHSLKLTKLTLLETEDSIDLVECLEGESLKENDDFSGNDDSDNEKALEGDLVKVSGVVGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIVKDKIKLPQFLSNEAHAILKGLLQKEPERRLGSGLSGAEEIKQHKWFKGINWKKLEAREVMPSFKPEVSGRQCIANFDKCWTDMSVLDSPASSPSSDPKANPFTNFTYVRPPPSFLHQSTTTL", "length": 465 }, "evidence": [ { "id": "A0ABI0P443", "url": "https://omabrowser.org/oma/group/A0ABI0P443/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8R4U9-1", "protein_name": "Serine/threonine-protein kinase Sgk2", "gene_name": "Sgk2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSPVGVPSPQPSRANGNINLGPSANPNARPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQSHIMAERNVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQREHRFLEPRARFYTAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVAACDLLQGLLHKDQRQRLGSKEDFLDIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFDPEFTQEAVSKSIGCTPDTMSSSSGASSAFLGFSYAQDDDDILDS", "length": 367 }, "evidence": [ { "id": "A0ABI0P443", "url": "https://omabrowser.org/oma/group/A0ABI0P443/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9HBY8-2", "protein_name": "Serine/threonine-protein kinase Sgk2", "gene_name": "SGK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSSPAGTPSPQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSIGCTPDTVASSSGASSAFLGFSYAPEDDDILDC", "length": 367 }, "evidence": [ { "id": "A0ABI0P443", "url": "https://omabrowser.org/oma/group/A0ABI0P443/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZS5-1", "protein_name": "Serine/threonine-protein kinase Sgk2", "gene_name": "Sgk2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSPVGVPSPQPSRANGNINLGPSANPNARPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQNHIMAERNVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVAACDLLQGLLHKDQRQRLGSKEDFLDIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFDPEFTQEAVSKSIGCTPDTVASSSGASSAFLGFSYAQDDDDILDS", "length": 367 }, "evidence": [ { "id": "A0ABI0P443", "url": "https://omabrowser.org/oma/group/A0ABI0P443/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P443", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P443", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ], "pmid": "" }, { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P443", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P443", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P443", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MA37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MA37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA37" } ] } ] }, { "uniprot_ac": "A0A3Q1MD82", "gene_name": "CDK16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD82" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1MD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD82" } ] } ] }, { "uniprot_ac": "A0A3Q1MEZ6", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MHH5", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] } ] }, { "uniprot_ac": "A0A3Q1MHL3", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] } ] }, { "uniprot_ac": "A0A3Q1MHM3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] } ] }, { "uniprot_ac": "A0A3Q1MI36", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] } ] }, { "uniprot_ac": "A0A3Q1MKC7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": 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"uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", 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"Ensembl Gene", "id": "ENSBTAG00000039978", "url": "https://www.ensembl.org/id/ENSBTAG00000039978" } ] } } ], "crossref": [ { "id": "ENSBTAG00000039978", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039978", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14003", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14003", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "112449560", "url": "https://www.ncbi.nlm.nih.gov/gene/112449560", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MDQVREC", "url": "https://omabrowser.org/oma/group/MDQVREC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346:SF84", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346:SF84", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024857723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024857723", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0P2C0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2C0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N1N4", "url": "https://www.uniprot.org/uniprotkb/F1N1N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N1N4-1", "url": "https://www.uniprot.org/uniprotkb/F1N1N4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAAGRKKLDQRAFLEQVHECRDNGYLLSSKKIGSGAFSKVYLAYATQERMRHNSKLASDLRGKRHTMVAIKIVSTAEAPAEFSRKFLPREISSLNATYKHLNVVQLYETFANSRRTYLVLELAAHGDLLEHINATSAHRRCPGLEEEEARRLLWQLVSAVAHCHNSGIVHRDLKCENILLDDRGCLKLSDFGFANRSGLKNSLLSTFCGSVAYTAPEILMSKKYNGEQADLWSLGVILYAMVTGKLPFKECQPHGMLYLMRRGPTFRPGLSPECQDLIRGLLQLRPRARLALQQVATHHWMLPAAHALFCTTLCAIPEKPEKPQLQTSLDNVEPSADSDPPRSLLQLWRPQLQGTSHESASSLTPEPPRACPRQVADSAGLQLWRTETAGRRVGRSRHPLLLCSIWSVPGHYLVS", "length": 416, "header": "tr|A0ABI0P2C0-1|A0ABI0P2C0_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=TSSK5 PE=4 SV=1 CANONICAL=A0ABI0P2C0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P2C0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0/entry#A0ABI0P2C0-1", "sequence": { "sequence": "MKAAGRKKLDQRAFLEQVHECRDNGYLLSSKKIGSGAFSKVYLAYATQERMRHNSKLASDLRGKRHTMVAIKIVSTAEAPAEFSRKFLPREISSLNATYKHLNVVQLYETFANSRRTYLVLELAAHGDLLEHINATSAHRRCPGLEEEEARRLLWQLVSAVAHCHNSGIVHRDLKCENILLDDRGCLKLSDFGFANRSGLKNSLLSTFCGSVAYTAPEILMSKKYNGEQADLWSLGVILYAMVTGKLPFKECQPHGMLYLMRRGPTFRPGLSPECQDLIRGLLQLRPRARLALQQVATHHWMLPAAHALFCTTLCAIPEKPEKPQLQTSLDNVEPSADSDPPRSLLQLWRPQLQGTSHESASSLTPEPPRACPRQVADSAGLQLWRTETAGRRVGRSRHPLLLCSIWSVPGHYLVS", "length": 416, "header": "tr|A0ABI0P2C0-1|A0ABI0P2C0_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=TSSK5 PE=4 SV=1 CANONICAL=A0ABI0P2C0-1" }, "locus": { "chromosome": "14", "start_pos": 712190, "end_pos": 709459, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150043.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150043.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107351.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107351.1" } ] } }, { "isoform_ac": "F1N1N4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0/entry#F1N1N4-1", "sequence": { "sequence": "MKAAGRKKLDQRAFLEQVHECRDNGYLLSSKKIGSGAFSKVYLAYATQERMRHNSKLASDLRGKRHTMVAIKIVSTAEAPAEFSRKFLPREISSLNATYKHLNVVQLYETFANSRRTYLVLELAAHGDLLEHINATSAHRRCPGLEEEEARRLLWQLVSAVAHCHNSGIVHRDLKCENILLDDRGCLKLSDFGFANRSGLKNSLLSTFCGSVAYTAPEILMSKKYNGEQADLWSLGVILYAMVTGKLPFKECQPHGMLYLMRRGPTFRPGLSPEKPEKPQLQTSLDNVEPSADSDPPRSLLQLWRPQLQGTSHESASSLTPEPPRACPRQVADSAGLQLWRTETAGRRVGRSRHPLLLCSIWSVPGHYLVS", "length": 371, "header": "tr|F1N1N4-1|A0ABI0P2C0_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=TSSK5 PE=4 SV=3 CANONICAL=A0ABI0P2C0-1" }, "locus": { "chromosome": "14", "start_pos": 712190, "end_pos": 709459, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056792.3", "url": "https://www.ensembl.org/id/ENSBTAT00000056792.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052999.3", "url": "https://www.ensembl.org/id/ENSBTAP00000052999.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZJ84-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Tssk5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSNSRRKEDQRVFIEQVRECMNNGYLLSSKKIGSGAFSKVYLAYATRERMKHNPRLSSDLRGKHHSMVAIKIVSMAEAPAEYSRKFLPREILSLNATYKHMNIVQLYETYQNSQRSYLVLELAARGDLLEYINAVSDLRCCPGLEEEEARRLFWQLVSAVAHCHSVGIVHRDLKCENILLDDQGFLKLTDFGFANWVGIKNSLLSTFCGSVAYTAPEILMSKKYNGEQADLWSLGIILHAMVSGKLPFKEHQPHRMLHLIRRGPIFRPRLSPECRDLIRGLLQLHPGDRLDLQQVAAHCWMLPAEHMLSSVLGATREQKHSWSAIGPDNAEPDRDTRYSRSKGSSPSSGRTSPRRASLAQLCSTWKPAPEE", "length": 372 }, "evidence": [ { "id": "A0ABI0P2C0", "url": "https://omabrowser.org/oma/group/A0ABI0P2C0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C1R0-1", "protein_name": "Testis-specific serine/threonine-protein kinase 5", "gene_name": "Tssk5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSSSWRKSDQRVFIEQVRECMNNGYLLSSKKIGSGAFSKVYLAYATRERMKHNPRLSSDLRGKRHTMVAIKIVSMAEAPAEYSRKFLPREILSLNATYKHMNIVQLYETYQNSQRSYLVLELAARGDLLEHINAVSDLRCCPGLEEEEARRLFWQLVSAVAHCHNVGIVHRDLKCENILLDDQGFIKLTDFGFANWVGLKNSLLSTFCGSVAYTAPEILMSKKYNGEQADLWSLGIILHAMVSGKLPFKEHQPHRMLNLIRRGPIFRPGLSPECRDLIRGLLQLHPCERLDLQQVAAHCWMLPAEHMLSSALGAPREQDHSWSTVAPDNTEPDRDTRHARSKGSSSSSGRTSPRRPSLAQLCNTWKPAPEQ", "length": 372 }, "evidence": [ { "id": "A0ABI0P2C0", "url": "https://omabrowser.org/oma/group/A0ABI0P2C0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2C0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2C0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2C0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M334" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M334", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M334" } ] } ] }, { "uniprot_ac": "A0A3Q1M4N6", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4N6" } ] } ] }, { "uniprot_ac": "A0A3Q1M4X3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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{ "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] } ] }, { "uniprot_ac": "Q4TVR5", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] } ] }, { "uniprot_ac": "Q58D94", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] } ] }, { "uniprot_ac": "Q5E9L6", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] } ] }, { "uniprot_ac": "Q5E9X2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] } ] }, { "uniprot_ac": "Q5E9Y0", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] } ] }, { "uniprot_ac": "Q5E9Y9", "gene_name": "NME7", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] } ] }, { "uniprot_ac": "Q6TJY3", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] } ] }, { "uniprot_ac": "Q7YRC6", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] } ] }, { "uniprot_ac": "Q8MIT6", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] } ] }, { "uniprot_ac": "Q95KV0", "gene_name": "IKBKB", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] } ] }, { "uniprot_ac": "Q9N0P9", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] } ] }, { "uniprot_ac": "V6F977", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 302, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P3F2-1", "uniprot_ac": "A0ABI0P3F2", "uniprot_id": "A0ABI0P3F2_BOVIN", "mass": { "chemical_mass": 76212.0, "monoisotopic_mass": 76212.0 }, "refseq": {}, "gene_names": [ { "name": "DDX3X", "type": "recommended", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] }, { "name": "DDX3Y", "type": "recommended", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] }, { "name": "DDX3Y", "type": "synonym", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] } ], "protein_names": [ { "name": "RNA helicase", "type": "recommended", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DDX3Y", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000035907", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000035907", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3MWJ8", "url": "https://www.orthodb.org/?gene=G3MWJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G5E631", "url": "https://www.orthodb.org/?gene=G5E631", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9ST52", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9ST52-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TH84", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TH84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TH84-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TH84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWX8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWX8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NY60", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NY60-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3F2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWJ8", "url": "https://www.uniprot.org/uniprotkb/G3MWJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWJ8-1", "url": "https://www.uniprot.org/uniprotkb/G3MWJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E631", "url": "https://www.uniprot.org/uniprotkb/G5E631", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E631-1", "url": "https://www.uniprot.org/uniprotkb/G5E631-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSHLKLSPILAANLSSLYHHTPVEHLCSKTQQEAGVSRELRLADLNLNSDNNQSGGGSTASKGRYIPPHLRNREASKGFYGKGSSGWSCSKEKDAYSSFGSRDSRGRPSYFSDRGSGSRGRFDDRGRNECEGFGSRGDRTGFGRFERSGHSRWCDKSDDDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEVTGNNCPPHIESFSDVAMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKESGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVLPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIIEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEADKRSFLLDLLNATGTDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPGDIEEYVHRIGRTGRVGNLGLATSFFNERNINISKDLLDLLVEAKQEVPSWLENMAYEHHYKSSNRGRSRRFSGGFGARDYRQSSSSGSFSYSSGRAGSSRSGGGAHGSSRGFGGGSGYGGFYSSEGYGGNYSSQGVDWWGN", "length": 688, "header": "tr|A0ABI0P3F2-1|A0ABI0P3F2_BOVIN Isoform 1 of RNA helicase OS=Bos taurus OX=9913 GN=DDX3Y PE=1 SV=1 CANONICAL=A0ABI0P3F2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9ST52-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2/entry#A0AAA9ST52-1", "sequence": { "sequence": "MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASRFYDKDSSGWSSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRGDYDGIGGRGDRGGFGKYERGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGARDYRQSSGGSSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGSFYNSDGYGGNYNSQGVDWWGN", "length": 645, "header": "tr|A0AAA9ST52-1|A0ABI0P3F2_BOVIN Computationally mapped isoform of RNA helicase OS=Bos taurus OX=9913 GN=DDX3Y PE=1 SV=1 CANONICAL=A0ABI0P3F2-1" }, "locus": { "chromosome": "X", "start_pos": 102232222, "end_pos": 102219714, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132088.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132088.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087304.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087304.1" } ] } }, { "isoform_ac": "A0AAA9TH84-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2/entry#A0AAA9TH84-1", "sequence": { "sequence": "MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGWSSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRGDYDGIGGRGDRGGFGKYERGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGARDYRQSSGGSSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGSFYNSDGYGGNYNSQGVDWWGN", "length": 628, "header": "tr|A0AAA9TH84-1|A0ABI0P3F2_BOVIN Computationally mapped isoform of RNA helicase OS=Bos taurus OX=9913 GN=DDX3Y PE=1 SV=1 CANONICAL=A0ABI0P3F2-1" }, "locus": { "chromosome": "X", "start_pos": 102232222, "end_pos": 102219714, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120749.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120749.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097882.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097882.1" } ] } }, { "isoform_ac": "A0AAA9TWX8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2/entry#A0AAA9TWX8-1", "sequence": { "sequence": "MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGWSSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRGDYDGIGGRGDRGGFGKYERGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGARDYRQSSGGSSSSFSSSRASSSRSGGGGYGSFYNSDGYGGNYNSQGVDWWGN", "length": 650, "header": "tr|A0AAA9TWX8-1|A0ABI0P3F2_BOVIN Computationally mapped isoform of RNA helicase OS=Bos taurus OX=9913 GN=DDX3Y PE=1 SV=1 CANONICAL=A0ABI0P3F2-1" }, "locus": { "chromosome": "X", "start_pos": 102232222, "end_pos": 102219714, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111134.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111134.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101970.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101970.1" } ] } }, { "isoform_ac": "A0ABI0NY60-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2/entry#A0ABI0NY60-1", "sequence": { "sequence": "MSHEAVKNVQEVDQQLADLNLNSDNNQSGGGSTASKGRYIPPHLRNREASKGFYGKGSSGWSCSKEKDAYSSFGSRDSRGRPSYFSDRGSGSRGRFDDRGRNECEGFGSRGDRTGFGRFERSGHSRWCDKSDDDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEVTGNNCPPHIESFSDVAMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKESGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVLPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIIEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEADKRSFLLDLLNATGTDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPGDIEEYVHRIGRTGRVGNLGLATSFFNERNINISKDLLDLLVEAKQEVPSWLENMAYEHHYKSSNRGRSRRFSGGFGARDYRQSSSSGSFSYSSGRAGSSRSGGGAHGSSRGFGGGSSRIFPLLYFCKGFLPFSKHNLINFICEEHNQIMFLIRLFY", "length": 676, "header": "tr|A0ABI0NY60-1|A0ABI0P3F2_BOVIN Computationally mapped isoform of RNA helicase OS=Bos taurus OX=9913 GN=DDX3Y PE=1 SV=1 CANONICAL=A0ABI0P3F2-1" }, "locus": { "chromosome": "Y", "start_pos": 7682660, "end_pos": 7672784, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143304.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143304.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104838.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104838.1" } ] } }, { "isoform_ac": "A0ABI0P3F2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2/entry#A0ABI0P3F2-1", "sequence": { "sequence": "MKSHLKLSPILAANLSSLYHHTPVEHLCSKTQQEAGVSRELRLADLNLNSDNNQSGGGSTASKGRYIPPHLRNREASKGFYGKGSSGWSCSKEKDAYSSFGSRDSRGRPSYFSDRGSGSRGRFDDRGRNECEGFGSRGDRTGFGRFERSGHSRWCDKSDDDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEVTGNNCPPHIESFSDVAMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKESGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVLPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIIEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEADKRSFLLDLLNATGTDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPGDIEEYVHRIGRTGRVGNLGLATSFFNERNINISKDLLDLLVEAKQEVPSWLENMAYEHHYKSSNRGRSRRFSGGFGARDYRQSSSSGSFSYSSGRAGSSRSGGGAHGSSRGFGGGSGYGGFYSSEGYGGNYSSQGVDWWGN", "length": 688, "header": "tr|A0ABI0P3F2-1|A0ABI0P3F2_BOVIN Isoform 1 of RNA helicase OS=Bos taurus OX=9913 GN=DDX3Y PE=1 SV=1 CANONICAL=A0ABI0P3F2-1" }, "locus": { "chromosome": "Y", "start_pos": 7706809, "end_pos": 7672611, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137066.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137066.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105812.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105812.1" } ] } }, { "isoform_ac": "G3MWJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2/entry#G3MWJ8-1", "sequence": { "sequence": "MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGWSSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRGDYDGIGGRGDRGGFGKYERGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGARDYRQSSGGSSSSFSSSRASSSRSGGGGHGSSRGFGGELGA", "length": 639, "header": "tr|G3MWJ8-1|A0ABI0P3F2_BOVIN Computationally mapped isoform of RNA helicase OS=Bos taurus OX=9913 GN=DDX3Y PE=1 SV=2 CANONICAL=A0ABI0P3F2-1" }, "locus": { "chromosome": "X", "start_pos": 102232222, "end_pos": 102208879, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065838.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065838.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053899.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053899.3" } ] } }, { "isoform_ac": "G5E631-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2/entry#G5E631-1", "sequence": { "sequence": "MDPWCNCHGLCGVLADLNLNSDNNQSGGGSTASKGRYIPPHLRNREASKGFYGKGSSGWSCSKEKDAYSSFGSRDSRGRPSYFSDRGSGSRGRFDDRGRNECEGFGSRGDRTGFGRFERSGHSRWCDKSDDDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEVTGNNCPPHIESFSDVAMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKESGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVLPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIIEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEADKRSFLLDLLNATGTDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPGDIEEYVHRIGRTGRVGNLGLATSFFNERNINISKDLLDLLVEAKQEVPSWLENMAYEHHYKSSNRGRSRRFSGGFGARDYRQSSSSGSFSYSSGRAGSSRSGGGAHGSSRGFGGGSGYGGFYSSEGYGGNYSSQGVDWWGN", "length": 659, "header": "tr|G5E631-1|A0ABI0P3F2_BOVIN Computationally mapped isoform of RNA helicase OS=Bos taurus OX=9913 GN=DDX3Y PE=1 SV=3 CANONICAL=A0ABI0P3F2-1" }, "locus": { "chromosome": "Y", "start_pos": 7699909, "end_pos": 7672611, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000050399.6", "url": "https://www.ensembl.org/id/ENSBTAT00000050399.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000047104.5", "url": "https://www.ensembl.org/id/ENSBTAP00000047104.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 20, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "ribosomal small subunit binding", "id": "GO:0043024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043024", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "eukaryotic initiation factor 4E binding", "id": "GO:0008190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008190", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "poly(A) binding", "id": "GO:0008143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008143", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "RNA strand annealing activity", "id": "GO:0033592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033592", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "CTPase activity", "id": "GO:0043273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043273", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "mRNA 5'-UTR binding", "id": "GO:0048027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048027", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "RNA stem-loop binding", "id": "GO:0035613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035613", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 38, "go_terms": [ { "name": "positive regulation of interferon-alpha production", "id": "GO:0032727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032727", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "protein localization to cytoplasmic stress granule", "id": "GO:1903608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903608", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "positive regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901224", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "negative regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901223", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "negative regulation of protein-containing complex assembly", "id": "GO:0031333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031333", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "positive regulation of G1/S transition of mitotic cell cycle", "id": "GO:1900087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900087", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway", "id": "GO:0097193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097193", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "id": "GO:1902042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902042", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "extrinsic apoptotic signaling pathway via death domain receptors", "id": "GO:0008625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008625", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "stress granule assembly", "id": "GO:0034063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034063", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "negative regulation of intrinsic apoptotic signaling pathway", "id": "GO:2001243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001243", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "positive regulation of toll-like receptor 7 signaling pathway", "id": "GO:0034157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034157", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "positive regulation of translation in response to endoplasmic reticulum stress", "id": "GO:0036493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036493", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "positive regulation of viral genome replication", "id": "GO:0045070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045070", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "positive regulation of translational initiation", "id": "GO:0045948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045948", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "cytosolic ribosome assembly", "id": "GO:0042256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042256", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial translation", "id": "GO:0070131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070131", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "positive regulation of protein K63-linked ubiquitination", "id": "GO:1902523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902523", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "positive regulation of interferon-beta production", "id": "GO:0032728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032728", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "cellular response to osmotic stress", "id": "GO:0071470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071470", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "cellular response to arsenic-containing substance", "id": "GO:0071243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071243", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "cytoplasmic pattern recognition receptor signaling pathway", "id": "GO:0002753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002753", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "positive regulation of toll-like receptor 8 signaling pathway", "id": "GO:0034161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034161", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "gamete generation", "id": "GO:0007276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007276", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex", "id": "GO:0005852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005852", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" }, { "name": "P granule", "id": "GO:0043186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043186", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3F2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" }, { "start_pos": 677, "end_pos": 679, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", "F1N2W9-1", "E1BB03-1", "E1BMP7-1", "A0JND9-1", "E1BAS6-1", "A0AAA9RXM7-1", "Q59HJ6-1", "Q2KJ94-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "A0AAF6Z0E4-1", "G3MZH7-1", "F1MKC7-1", "A0AAA9S7V9-1", "A0AAF6YME1-1", "F1MFR1-1", "Q3T084-1", "E1B7X9-1", "A0ABI0P204-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "R-BTA-6798748", "name": "Exocytosis of secretory granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, secretory granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19120-1", "P68401-1", "A0JNA3-1", "F1MMD5-1", "A0AAA9S4U4-1", "P80177-1", "Q0II59-1", "Q0VCM4-1", "Q3SWY3-1", "Q3SYU2-1", "F1MHT1-1", "A0AAA9RV00-1", "A0ABI0P3F2-1", "P62935-1", "P68103-1", "Q3T0Q4-1", "A0A452DJA8-1", "E1BNY9-1", "A0A3Q1LMV5-1", "A0A3Q1LTT9-1", "A1A4J1-1", "F1MQ78-1", "G3X757-1", "P00432-1", "Q76LV2-1", "A0A140T8A5-1", "A0A3Q1LR63-1", "Q56JW4-1", "Q3T0A3-1", "Q3ZBD7-1", "Q58DK5-1", "Q3SZ62-1", "Q3T0V9-1", "Q3ZCI9-1" ], "evidence": [ { "id": "R-BTA-6798748", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798748" } ] }, { "id": "R-BTA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P19120-1", "P68401-1", "P80227-1", "A0JNA3-1", "F1MMD5-1", "Q32PF2-1", "Q3SZH7-1", "A0AAA9S4U4-1", "A0AAA9S9V5-1", "P07688-1", "O46414-1", "P25326-1", "P80177-1", "Q0VCM4-1", "Q3SWY3-1", "Q3SYU2-1", "F1MHT1-1", "F1MMR6-1", "A0ABI0NJH4-1", "A0AAA9RV00-1", "A0ABI0P3F2-1", "P05689-1", "P46196-1", "P52176-1", "P62935-1", "P68103-1", "Q17QB3-1", "Q3T0Q4-1", "Q27970-1", "A0A452DJA8-1", "E1BNY9-1", "A0A3Q1LMV5-1", "A0A3Q1LTT9-1", "A0AAA9SYX5-1", "A1A4J1-1", "E1BB52-1", "F1MQ78-1", "G3X757-1", "P00432-1", "Q76LV2-1", "A0A140T8A5-1", "A0A3Q1LR63-1", "A0A3Q1NDQ7-1", "Q3T0A3-1", "Q3ZBD7-1", "Q58DK5-1", "Q3SZ62-1", "Q3T0V9-1", "Q3ZCI9-1" ], "evidence": [ { "id": "R-BTA-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6800434" } ] } ], 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"activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A3Q1LMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A3Q1LMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ] } ] }, { "uniprot_ac": "A0A3Q1LQC3", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", 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"ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1LXD0", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] } ] }, { "uniprot_ac": "A0A3Q1M0A4", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A3Q1M0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0A4" } ] } ] }, { "uniprot_ac": "A0A3Q1M155", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1M155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M155" } ] } ] }, { "uniprot_ac": "A0A3Q1M493", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU57" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1MU57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU57" } ] } ] }, { "uniprot_ac": "A0A3Q1NDQ7", "gene_name": "GLB1", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "A0A3Q1NDQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NDQ7" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "A0A3Q1NDQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NDQ7" } ] } ] }, { "uniprot_ac": "A0A3Q1NMG4", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] } ] }, { "uniprot_ac": "A0A452DJA8", "gene_name": "PNP", "activity": [ { "ec_number": "2.4.2.1", "activity": "adenosine + phosphate = alpha-D-ribose 1-phosphate + adenine.", "evidence": [ { "id": "A0A452DJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A452DJA8" } ] }, { "ec_number": "2.4.2.1", "activity": "", "evidence": [ { "id": "A0A452DJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A452DJA8" } ] } ] }, { "uniprot_ac": "A0AAA9RRF7", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RRF7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", 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phosphate + H(+).", "evidence": [ { "id": "A0AAA9S5G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5G9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0AAA9S5G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5G9" } ] } ] }, { "uniprot_ac": "A0AAA9S7V9", "gene_name": "RECQL4", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0AAA9S7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V9" } ] } ] }, { "uniprot_ac": "A0AAA9S9V5", "gene_name": "CANT1", "activity": [ { "ec_number": "3.6.1.6", "activity": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S9V5", "database": 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replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] } ] }, { "uniprot_ac": "A6QQR4", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] } ] }, { "uniprot_ac": "A7YSY2", "gene_name": "AFG2B", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] } ] }, { "uniprot_ac": "A7Z019", "gene_name": "SMARCA4", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A7Z019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7Z019" } ] } ] }, { "uniprot_ac": "E1B7X9", "gene_name": "SMARCAD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1B7X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7X9" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B9N7", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] } ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BAN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAN8" } ] } ] }, { "uniprot_ac": "E1BAS6", "gene_name": "SETX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] } ] }, { "uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BNY9", "gene_name": "HUWE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MHT1", "gene_name": "AGL", "activity": [ { "ec_number": "2.4.1.25", "activity": "Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.", "evidence": [ { "id": "F1MHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHT1" } ] }, { "ec_number": "3.2.1.33", "activity": "Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.", "evidence": [ { "id": "F1MHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHT1" } ] }, { "ec_number": "3.2.1.33", "activity": "", "evidence": [ { "id": "F1MHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHT1" } ] }, { "ec_number": "2.4.1.25", "activity": "", "evidence": [ { "id": "F1MHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MHT1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMR6", "gene_name": "CTSD", "activity": [ { "ec_number": "3.4.23.5", "activity": "Specificity similar to, but narrower than, that of pepsin A. Does not cleave the 4-Gln-|-His-5 bond in B chain of insulin.", "evidence": [ { "id": "F1MMR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMR6" } ] }, { "ec_number": "3.4.23.5", "activity": "", "evidence": [ { "id": "F1MMR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMR6" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MQ78", "gene_name": "ALOX5", "activity": [ { "ec_number": "1.13.11.34", "activity": "(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = leukotriene A4 + H2O.", "evidence": [ { "id": "F1MQ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ78" } ] }, { "ec_number": "1.13.11.12", "activity": "(9Z,12Z,15Z)-octadecatrienoate + O2 = (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate.", "evidence": [ { "id": "F1MQ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ78" } ] }, { "ec_number": "1.13.11.34", "activity": "", "evidence": [ { "id": "F1MQ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ78" } ] }, { "ec_number": "1.13.11.12", "activity": "", "evidence": [ { "id": "F1MQ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ78" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "O18956", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] } ] }, { "uniprot_ac": "O46414", "gene_name": "FTH1", "activity": [ { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "O46414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46414" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "O46414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46414" } ] } ] }, { "uniprot_ac": "P00432", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "P00432", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00432" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "P00432", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00432" } ] } ] }, { "uniprot_ac": "P05689", "gene_name": "CTSZ", "activity": [ { "ec_number": "3.4.18.1", "activity": "Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity.", "evidence": [ { "id": "P05689", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05689" } ] }, { "ec_number": "3.4.18.1", "activity": "", "evidence": [ { "id": "P05689", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05689" } ] } ] }, { "uniprot_ac": "P07688", "gene_name": "CTSB", "activity": [ { "ec_number": "3.4.22.1", "activity": "Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.", "evidence": [ { "id": "P07688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07688" } ] }, { "ec_number": "3.4.22.1", "activity": "", "evidence": [ { "id": "P07688", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07688" } ] } ] }, { "uniprot_ac": "P09487", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.9.1.1", "activity": "N-phosphocreatine + H2O = creatine + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] } ] }, { "uniprot_ac": "P19120", "gene_name": "HSPA8", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] } ] }, { "uniprot_ac": "P25326", "gene_name": "CTSS", "activity": [ { "ec_number": "3.4.22.27", "activity": "Similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.", "evidence": [ { "id": "P25326", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25326" } ] }, { "ec_number": "3.4.22.27", "activity": "", "evidence": [ { "id": "P25326", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25326" } ] } ] }, { "uniprot_ac": "P35071", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "P35071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35071" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P52176", "gene_name": "MMP9", "activity": [ { "ec_number": "3.4.24.35", "activity": "Cleavage of gelatin types I and V and collagen types IV and V.", "evidence": [ { "id": "P52176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52176" } ] }, { "ec_number": "3.4.24.35", "activity": "", "evidence": [ { "id": "P52176", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52176" } ] } ] }, { "uniprot_ac": "P60712", "gene_name": "ACTB", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P60712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P60712" } ] } ] }, { "uniprot_ac": "P62739", "gene_name": "ACTA2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P62739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62739" } ] } ] }, { "uniprot_ac": "P62935", "gene_name": "PPIA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P62935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62935" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P62935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62935" } ] } ] }, { "uniprot_ac": "P63258", "gene_name": "ACTG1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P63258" } ] } ] }, { "uniprot_ac": "P68103", "gene_name": "EEF1A1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P68103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68103" } ] } ] }, { "uniprot_ac": "P68138", "gene_name": "ACTA1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68138" } ] } ] }, { "uniprot_ac": "P68401", "gene_name": "PAFAH1B2P68402", "activity": [ { "ec_number": "3.1.1.47", "activity": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+).", "evidence": [ { "id": "P68401", 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"id": "Q0IIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIK5" } ] } ] }, { "uniprot_ac": "Q0V8B7", "gene_name": "MCM5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0V8B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8B7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q0V8B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8B7" } ] } ] }, { "uniprot_ac": "Q0V8H6", "gene_name": "MOV10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q0V8H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8H6" } ] }, { "ec_number": "5.6.2.5", "activity": "n ATP + n H2O + wound RNA = n ADP 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P0B9-1", "uniprot_ac": "A0ABI0P0B9", "uniprot_id": "A0ABI0P0B9_BOVIN", "mass": { "chemical_mass": 54505.0, "monoisotopic_mass": 54505.0 }, "refseq": { "ac": "NP_001179521", "name": "E3 ubiquitin-protein ligase Hakai", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179521" }, "gene_names": [ { "name": "CBLL1", "type": "recommended", "evidence": [ { "id": "A0ABI0P0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9" } ] }, { "name": "CBLL1", "type": "synonym", "evidence": [ { "id": "NP_001179521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179521" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase Hakai", "type": "recommended", "evidence": [ { "id": "A0ABI0P0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0ABI0P0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9/entry#names_and_taxonomy" } ] }, { "name": "Cas-Br-M ecotropic retroviral transforming sequence-like 1", "type": "synonym", "evidence": [ { "id": "NP_001179521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179521" } ] }, { "name": "Casitas B-lineage lymphoma-transforming sequence-like protein 1", "type": "synonym", "evidence": [ { "id": "A0ABI0P0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase Hakai", "type": "synonym", "evidence": [ { "id": "NP_001179521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179521" } ] }, { "name": "RING-type E3 ubiquitin transferase Hakai", "type": "synonym", "evidence": [ { "id": "A0ABI0P0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "E3 ubiquitin-protein ligase that mediates ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation. Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Its function in the WMM complex is unknown.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TAP8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAP8#function" }, { "database": "UniProtKB", "id": "ARBA00057512", "url": "https://www.uniprot.org/uniprotkb/ARBA00057512#function" }, { "database": "UniProtKB", "id": "A0AAA9TGH7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGH7#function" }, { "database": "UniProtKB", "id": "A0ABI0P0B9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0B9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CBLL1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9", "locus": { "chromosome": "4", "start_pos": 48773761, "end_pos": 48742753, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018348", "url": "https://www.ensembl.org/id/ENSBTAG00000018348" } ] } } ], "crossref": [ { "id": "ENSBTAG00000018348", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018348", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16508", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16508", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "524139", "url": "https://www.ncbi.nlm.nih.gov/gene/524139", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:524139", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524139", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HLPPKQH", "url": "https://omabrowser.org/oma/group/HLPPKQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MEB7", "url": "https://www.orthodb.org/?gene=F1MEB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13480", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13480", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13480:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13480:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF18408", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18408", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9766229", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9766229", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9958810", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958810", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179521", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179521", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TAP8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAP8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGH7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGH7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0B9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0B9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MEB7", "url": "https://www.uniprot.org/uniprotkb/F1MEB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MEB7-1", "url": "https://www.uniprot.org/uniprotkb/F1MEB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDHTDNELQGTNSSGSLGGLDVRRRIPIKLISKQGNKAKASPRTPRTINRMPAKAPAGDEEGFDYNEEERYDCKGGELFGNQRRFPGHLFWDFQINILGEKDDTPVHFCDKCGLPIKIYGRMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAGKPVTRASLENVHPPPIAPPPAEIPDRFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNPGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRMQGPPSQTPLPGPHHPDQTRYRPYYQ", "length": 492, "header": "tr|A0ABI0P0B9-1|A0ABI0P0B9_BOVIN Isoform 1 of E3 ubiquitin-protein ligase Hakai OS=Bos taurus OX=9913 GN=CBLL1 PE=3 SV=1 CANONICAL=A0ABI0P0B9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TAP8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9/entry#A0AAA9TAP8-1", "sequence": { "sequence": "MVFGMIPGAAFLLKPIACPALQLWSLTTTSLELKIKIFSSLSTNNELQGTNSSGSLGGLDVRRRIPIKLISKQGNKAKASPRTPRTINRMPAKAPAGDEEGFDYNEEERYDCKGGELFGNQRRFPGHLFWDFQINILGEKDDTPVHFCDKCGLPIKIYGRMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAGKPVTRASLENVHPPPIAPPPAEIPDRFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNPGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRMQGPPSQTPLPGPHHPDQTRYRPYYQ", "length": 531, "header": "tr|A0AAA9TAP8-1|A0ABI0P0B9_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase Hakai OS=Bos taurus OX=9913 GN=CBLL1 PE=3 SV=1 CANONICAL=A0ABI0P0B9-1" }, "locus": { "chromosome": "4", "start_pos": 48773340, "end_pos": 48759677, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099625.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099625.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093085.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093085.1" } ] } }, { "isoform_ac": "A0AAA9TGH7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9/entry#A0AAA9TGH7-1", "sequence": { "sequence": "MKAAATTNPWDQELELDNELQGTNSSGSLGGLDVRRRIPIKLISKQGNKAKASPRTPRTINRMPAKAPAGDEEGFDYNEEERYDCKGGELFGNQRRFPGHLFWDFQINILGEKDDTPVHFCDKCGLPIKIYGRMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAGKPVTRASLENVHPPPIAPPPAEIPDRFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNPGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRMQGPPSQTPLPGPHHPDQTRYRPYYQ", "length": 504, "header": "tr|A0AAA9TGH7-1|A0ABI0P0B9_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase Hakai OS=Bos taurus OX=9913 GN=CBLL1 PE=3 SV=1 CANONICAL=A0ABI0P0B9-1" }, "locus": { "chromosome": "4", "start_pos": 48773340, "end_pos": 48758080, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106968.2", "url": "https://www.ensembl.org/id/ENSBTAT00000106968.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097291.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097291.1" } ] } }, { "isoform_ac": "A0ABI0P0B9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9/entry#A0ABI0P0B9-1", "sequence": { "sequence": "MDHTDNELQGTNSSGSLGGLDVRRRIPIKLISKQGNKAKASPRTPRTINRMPAKAPAGDEEGFDYNEEERYDCKGGELFGNQRRFPGHLFWDFQINILGEKDDTPVHFCDKCGLPIKIYGRMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAGKPVTRASLENVHPPPIAPPPAEIPDRFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNPGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRMQGPPSQTPLPGPHHPDQTRYRPYYQ", "length": 492, "header": "tr|A0ABI0P0B9-1|A0ABI0P0B9_BOVIN Isoform 1 of E3 ubiquitin-protein ligase Hakai OS=Bos taurus OX=9913 GN=CBLL1 PE=3 SV=1 CANONICAL=A0ABI0P0B9-1" }, "locus": { "chromosome": "4", "start_pos": 48773340, "end_pos": 48759164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153026.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153026.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107573.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107573.1" } ] } }, { "isoform_ac": "F1MEB7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9/entry#F1MEB7-1", "sequence": { "sequence": "MDHTDNELQGTNSSGSLGGLDVRRRIPIKLISKQGNKAKASPRTPRTINRMPAKAPAGDEEGFDYNEEERYDCKGGELFGNQRRFPGHLFWDFQINILGEKDDTPVHFCDKCGLPIKIYGRML", "length": 123, "header": "tr|F1MEB7-1|A0ABI0P0B9_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase Hakai OS=Bos taurus OX=9913 GN=CBLL1 PE=3 SV=3 CANONICAL=A0ABI0P0B9-1" }, "locus": { "chromosome": "4", "start_pos": 48772307, "end_pos": 48759164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024413.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024413.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024413.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024413.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:524139", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524139", "resource": "KEGG Pathway" }, { "id": "R-BTA-9766229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9766229", "resource": "Reactome", "description": "Degradation of CDH1" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" }, { "id": "R-BTA-9958810", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958810", "resource": "Reactome", "description": "SRC activates STAT3 in a quantitative manner, through Cadherin-11 (CDH11), RAC1 and gp130 (IL6ST)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AJZ8-1", "protein_name": "E3 ubiquitin-protein ligase Hakai", "gene_name": "Cbll1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDHTDNELQGTNSSGSLGGLDVRRRIPIKLISKQANKVKPAPRTQRTVSRMPAKAAQEGFDYNEEQRYDCKGGELFGNQRRFPGHLFWDFKINILGEKDDTPVHFCDKCGLPIKVYGRMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAGKPVTRASLENVHPPIAPPPTEIPDRFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSSSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRMQGPPSQTPLPGPHHPDQTRYRPYYQ", "length": 488 }, "evidence": [ { "id": "A0ABI0P0B9", "url": "https://omabrowser.org/oma/group/A0ABI0P0B9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1P6L1-1", "protein_name": "E3 ubiquitin-protein ligase Hakai", "gene_name": "cbll1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDHSDNDMQGTDGPLGGPDVRRRIPIKLLPKQARNKPAPRPQRPTGRLPSKSHSAEEGFNFKKEDRFDCGVKSGDAFASQRRFPQQLYWDYKLNLVGEKDETPVHFCDKCGLPIKTYGRMIPCKHVFCYDCALHHERKGDKMCPGLNMYSCTDPVQRIEQCQRGSLYMCSIVQGCKRTYLSQRDLQAHINHRHMRSGKSSSSRSDSLHLPPSEVSDRFRVPPPHLPKPHVLIPPPLGHPGHDPYGPPPSAHDDLRPQGQPPGDMGPSRSLSQETFRISTVTTRKHSNLITVPIQDDSGSGPSRDPLSQPGNPPPPHHHPGDYTGQPVVTHPHHMMAPPQQHYGPPPPPPISHPMPHPGQGSNTPHMVFNQAPPPLSSVPPPITPPPGHLIGQMPPFMNHPPPGPPPQHGGPPVNAPPPHHYNPQFAEDKSTLSPPFNQPGGLSPGMWPAPRGPPPRMQGPPPQGQMPGPHHPDQGRYRPYYQ", "length": 482 }, "evidence": [ { "id": "A0ABI0P0B9", "url": "https://omabrowser.org/oma/group/A0ABI0P0B9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5ZHZ4-1", "protein_name": "E3 ubiquitin-protein ligase Hakai", "gene_name": "CBLL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDHNDNDLQGTNSSASLGGLDVRRRIPIKLISKQTNKTKPAPRAPRAMNRMPAKTQAGDEEEFDFNEEERYECKGGEMFGNQRRFPGPIFWDYKINLLGEKDDTPVHFCDKCGLPIKMYGRMIPCKHVFCYDCAILHEKKGDKMCPGCNEPVQRIEQCVRGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAGKPVTRPPLEPVHPPIAPPPAEIPERFIMPPEKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRPPPAEMSMAPPPPRPVSQDTFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQPVVTHPHHIMPPQQHYAPPPPPPPPISHPLQHPPQAAGTPHMVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVNVSAPPPHHYNPNSLPQFSEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRMQGPPAQAPLAGPHHPDQARYRPYYQ", "length": 493 }, "evidence": [ { "id": "A0ABI0P0B9", "url": "https://omabrowser.org/oma/group/A0ABI0P0B9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q75N03-1", "protein_name": "E3 ubiquitin-protein ligase Hakai", "gene_name": "CBLL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDHTDNELQGTNSSGSLGGLDVRRRIPIKLISKQANKAKPAPRTQRTINRMPAKAPPGDEEGFDYNEEERYDCKGGELFANQRRFPGHLFWDFQINILGEKDDTPVHFCDKCGLPIKIYGRMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAGKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHPDQTRYRPYYQ", "length": 491 }, "evidence": [ { "id": "A0ABI0P0B9", "url": "https://omabrowser.org/oma/group/A0ABI0P0B9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JIY2-1", "protein_name": "E3 ubiquitin-protein ligase Hakai", "gene_name": "Cbll1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDHTDNELQGTNSSGSLGGLDVRRRIPIKLISKQASKVKPAPRTQRTVSRMPAKAPQGDEEGFDYNEEQRYDCKGGELFGNQRRFPGHLFWDFKINILGEKDDTPVHFCDKCGLPIKVYGRMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAGKPVTRASLENVHPPIAPPPTDIPDRFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSSSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPAPRGPPPPPRMQGPPSQTPLPGPHHPDQTRYRPYYQ", "length": 491 }, "evidence": [ { "id": "A0ABI0P0B9", "url": "https://omabrowser.org/oma/group/A0ABI0P0B9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0B9", "url": 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"database": "UniProtKB", "id": "A0ABI0P0B9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0B9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0B9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0B9" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 149, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3L2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3L2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3P6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3P6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P499", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P499", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P499-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P499-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5U9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5U9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BH93", "url": "https://www.uniprot.org/uniprotkb/E1BH93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BH93-1", "url": "https://www.uniprot.org/uniprotkb/E1BH93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEKVSEAPEPVPRGCSSHGAPTPAPAVAAESSPGASSAESSSGSETLSEEGEPGFSREQPPPPPPGGARPAAAWAPALSVPERGVSAPPPRPGGAAPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPGKSLKFKRQLSEDGRHLRRGSLGGALTGRYLLPNPAAGQAWATSAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLIDSQKWNCLVKRCRTSNRKSLIGNGPSPALPRPHSPLSAHAGNSPQDSPRNFSPSASAHFSFARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPYQPTPDELHFLSKHFCTTESITTENRCRNTPMRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDHVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHNRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPLEEMAQLGNYDSGTAETPETDESVSSSNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRCLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHHMETEEEDDTNDEDFNVEIRQFSSCSHRFSKVFSSMDRGTQNSGEEKEDPGDKTKSTALPSTETLSWSSEYSEMQQLSTSNSSDTESNRHRRGAGLLPKLAVSAEAEHDGAAPRPRELHEEPEKPALPAAENAQEEPEVTTPASTISSSTLSDMFAVSPLGSPMSPHSLSSDPSSSRDSSPSRDSSGASASPHQPIVIHSLGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKTGPARRNSYKSRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLHTSRSFSCLNRSLSSGESLPGSPTHSLSPRSPTPSYRSTPDFPSGTNSSQSSSPSSSAPNSPAGSGHVRPSTLHGLAPKLSGQRYRSGRRKSAGSIPLSPLARTPSPTPQPTSPQRSPSPLLGHSLGNSKMAQAFPSKMHSPPTIVRHVVRPKSAEPPRSPLLKRVQSEEKLSPSYGGDKKHLCSRKHSLEVTQEEVPREQQQREVTLQSLEENVCDAPALSRARPVEQGCLKRPVSRKLGRQESVDELDREKLKAKVVVKKPDGLSEKQESRPKPHGLGSDLENLCAFRLEERDKKIYPKASERSNHFESKAAVQEAQPLCSLLKDALHKQANVRASEGVASEGATAAGDHGQGTCDFKRASTHSTLQDGLCHTTHRSTSGKGDTAEKAPQAKEGLRCEKLDGKLANIDYLRKKMSLEDKDESLCSVLKPKVTAGAQDCLPGSLGRPVGGQQEAPPASEARTPFIGSAHAAQLSAVSFVPLKALSGRVDSGAEKPGLAAPESPVRKSPSEYKLEGRSVSCLKPIEGTLDIALLSGPQASKTELPSPEPAQSPSPGSDVESPMPLALPSSTGRKADTAGQRESSPAGFKVNKSYLLEPRFPPASRGLQSSPVVAPPDPELKLDKKVSQAARAPATIMESHPQRGEGHPSQHQDHSPDVKLLPFPGQNLQGANTSRSRSPLLPESVPPREKPSGRELSERGPSIVGSEWSAVRPDIRRDPSKELCPPEAAKPSDNSQTPPVVGRTRLDVSTQTQALEKACGPCGRAKPRDGREEVRLPAREDSSLRSAGAPCERELGAERGLESKMEPASTRWSLEPPRPESEKSGRPSGFQSVQKDGPKEPERKEQPLQKYLTSSQPGPKEPERKEQPLQKHLPSSSQPGPKEPERKEQPLQKHVTSSSQPGPKEPERKEQPLQKHLPSSSQPGPKEPERKEQPLQKHVTSSSQLGPKEPERKEQPLQKHLPSSSQPGPKELERKEQCLQKHLTSSSQLGPKEPEMKEQPPQKHVTSSSQLCPKELERKEQPPQKHLTISSQLSPKEPERKEQPLQEHVTSSSQLSPKEPERKEQCLQKHFTSSSQLGPKEPETKEQPLQKHLTSSSQLSPKEPERKEQLLQEHLTSSSQLSPKEPERKEQCLQKHLTSSSQLGPKEPEMKEQPLQKHLTSSSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTSSCQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQLLQKHLTISSQLSPKEPERKEQLLQKHLTISSQLSPKEPEKKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQLLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQYLQKHLTSSSQLGPKEPETKEQPLQKHLTSSSQVGPKDPERKEQPPQKHLTSKSQPGPKEPERKEQCLQKHLTSSSQPGPKELERKEQPPLKHVTSSSQLGPREPERKEQPPQKHLTSSCQPPPPTKELPGLACQHCILPSHPAASLLGSKPCAIDSSFQDALRPTAVRSDSSSHKPRSDPDLGPPKSKFPDRPLSSQKPSAEAAVSKEPGAPTLGRAGVGSGKGVSEEFPVLPDPQNTAREVIGQGASGYSGPLPMEGGPLDTKLRPTSARCPPEALEMLGHPPGRGLLGASESVDQKLPTFRERQNLSPKAPTPSTVKDCPLPCKQTDRSPSPLATSTNAGKSEGKKCTEALYTPADGEKLGAGLSSVHSEAGPKGTEKPAAAAGKGWPEAKGKGLSPQKPLTEASKPSGMKRSPSATVQSSLRCATLPEKSLSYSCGFPEARPAVPETSTTSSDTSSAKAAGPAAESPASSSRDQQKPLPGGDGRTQMTKSDSLPCFRSSAITLESQHPSPGLVVVTSHRDRALSVTATVGETKGKEPAPTQPAQTRNQNVSREAAKPSPAPSTERPIVLPSEKDTGLRQRRGKESLRGSPHKKAL", "length": 3276, "header": "tr|A0ABI0P3P6-1|A0ABI0P3P6_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=MAST4 PE=3 SV=1 CANONICAL=A0ABI0P3P6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVG2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6/entry#A0A3Q1LVG2-1", "sequence": { "sequence": "MGEKVSEAPEPVPRGCSSHGAPTPAPAVAAESSPGASSAESSSGSETLSEEGEPGFSREQPPPPPPGGARPAAAWAPALSVPERGVSAPPPRPGGAAPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPGKSLKFKRQLSEDGRHLRRGSLGGALTGRYLLPNPAAGQAWATSAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLIDSQKWNCLVKRPVGPNAERVLLLR", "length": 243, "header": "tr|A0A3Q1LVG2-1|A0ABI0P3P6_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=MAST4 PE=3 SV=3 CANONICAL=A0ABI0P3P6-1" }, "locus": { "chromosome": "20", "start_pos": 13060643, "end_pos": 12640617, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080117.3", "url": "https://www.ensembl.org/id/ENSBTAT00000080117.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059287.3", "url": "https://www.ensembl.org/id/ENSBTAP00000059287.3" } ] } }, { "isoform_ac": "A0ABI0NJA8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6/entry#A0ABI0NJA8-1", "sequence": { "sequence": "MFAWRERIIEKFYLRRTSDSSQVSRVQIRKTQENAHLPVLPLMRRLDHILSPPPMPFRKCSNPDVASGPGKSLKFKRQLSEDGRHLRRGSLGGALTGRYLLPNPAAGQAWATSAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLIDSQKWNCLVKRCRTSNRKSLIGNGPSPALPRPHSPLSAHAGNSPQDSPRNFSPSASAHFSFARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPYQPTPDELHFLSKHFCTTESITTENRCRNTPMRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDHVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHNRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPLEEMAQLGNYDSGTAETPETDESVSSSNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRCLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHHMETEEEDDTNDEDFNVEIRQFSSCSHRFSKVFSSMDRGTQNSGEEKEDPGDKTKSTALPSTETLSWSSEYSEMQQLSTSNSSDTESNRHRRGAGLLPKLAVSAEAEHDGAAPRPRELHEEPEKPALPAAENAQEEPEVTTPASTISSSTLSDMFAVSPLGSPMSPHSLSSDPSSSRDSSPSRDSSGASASPHQPIVIHSLGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKTGPARRNSYKSRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLHTSRSFSCLNRSLSSGESLPGSPTHSLSPRSPTPSYRSTPDFPSGTNSSQSSSPSSSAPNSPAGSGHVRPSTLHGLAPKLSGQRYRSGRRKSAGSIPLSPLARTPSPTPQPTSPQRSPSPLLGHSLGNSKMAQAFPSKMHSPPTIVRHVVRPKSAEPPRSPLLKRVQSEEKLSPSYGGDKKHLCSRKHSLEVTQEEVPREQQQREVTLQSLEENVCDAPALSRARPVEQGCLKRPVSRKLGRQESVDELDREKLKAKVVVKKPDGLSEKQESRPKPHGLGSDLENLCAFRLEERDKKIYPKASERSNHFESKAAVQEAQPLCSLLKDALHKQANVRASEGVASEGATAAGDHGQGTCDFKRASTHSTLQDGLCHTTHRSTSGKGDTAEKAPQAKEGLRCEKLDGKLANIDYLRKKMSLEDKDESLCSVLKPKVTAGAQDCLPGSLGRPVGGQQEAPPASEARTPFIGSAHAAQLSAVSFVPLKALSGRVDSGAEKPGLAAPESPVRKSPSEYKLEGRSVSCLKPIEGTLDIALLSGPQASKTELPSPEPAQSPSPGSDVESPMPLALPSSTGRKADTAGQRESSPAGFKVNKSYLLEPRFPPASRGLQSSPVVAPPDPELKLDKKVSQAARAPATIMESHPQRGEGHPSQHQDHSPDVKLLPFPGQNLQGANTSRSRSPLLPESVPPREKPSGRELSERGPSIVGSEWSAVRPDIRRDPSKELCPPEAAKPSDNSQTPPVVGRTRLDVSTQTQALEKACGPCGRAKPRDGREEVRLPAREDSSLRSAGAPCERELGAERGLESKMEPASTRWSLEPPRPESEKSGRPSGFQSVQKDGPKEPERKEQPLQKYLTSSQPGPKEPERKEQPLQKHLPSSSQPGPKEPERKEQPLQKHVTSSSQPGPKEPERKEQPLQKHLPSSSQPGPKEPERKEQPLQKHVTSSSQLGPKEPERKEQPLQKHLPSSSQPGPKELERKEQCLQKHLTSSSQLGPKEPEMKEQPPQKHVTSSSQLCPKELERKEQPPQKHLTISSQLSPKEPERKEQPLQEHVTSSSQLSPKEPERKEQCLQKHFTSSSQLGPKEPETKEQPLQKHLTSSSQLSPKEPERKEQLLQEHLTSSSQLSPKEPERKEQCLQKHLTSSSQLGPKEPEMKEQPLQKHLTSSSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTSSCQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQLLQKHLTISSQLSPKEPERKEQLLQKHLTISSQLSPKEPEKKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQLLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQYLQKHLTSSSQLGPKEPETKEQPLQKHLTSSSQVGPKDPERKEQPPQKHLTSKSQPGPKEPERKEQCLQKHLTSSSQPGPKELERKEQPPLKHVTSSSQLGPREPERKEQPPQKHLTSSCQPPPPTKELPGLACQHCILPSHPAASLLGSKPCAIDSSFQDALRPTAVRSDSSSHKPRSDPDLGPPKSKFPDRPLSSQKPSAEAAVSKEPGAPTLGRAGVGSGKGVSEEFPVLPDPQNTAREVIGQGASGYSGPLPMEGGPLDTKLRPTSARCPPEALEMLGHPPGRGLLGASESVDQKLPTFRERQNLSPKAPTPSTVKDCPLPCKQTDRSPSPLATSTNAGKSEGKKCTEALYTPADGEKLGAGLSSVHSEAGPKGTEKPAAAAGKGWPEAKGKGLSPQKPLTEASKPSGMKRSPSATVQSSLRCATLPEKSLSYSCGFPEARPAVPETSTTSSDTSSAKAAGPAAESPASSSRDQQKPLPGGDGRTQMTKSDSLPCFRSSAITLESQHPSPGLVVVTSHRDRALSVTATVGETKGKEPAPTQPAQTRNQNVSREAAKPSPAPSTERPIVLPSEKDTGLRQRRGKESLRGSPHKKAL", "length": 3207, "header": "tr|A0ABI0NJA8-1|A0ABI0P3P6_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=MAST4 PE=3 SV=1 CANONICAL=A0ABI0P3P6-1" }, "locus": { "chromosome": "20", "start_pos": 13051846, "end_pos": 12445002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147934.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147934.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104183.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104183.1" } ] } }, { "isoform_ac": "A0ABI0NQV0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6/entry#A0ABI0NQV0-1", "sequence": { "sequence": "MDESSILRRRGLQKELSLPRRGSLIDSQKWNCLVKRCRTSNRKSLIGNGPSPALPRPHSPLSAHAGNSPQDSPRNFSPSASAHFSFARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPYQPTPDELHFLSKHFCTTESITTENRCRNTPMRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDHVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHNRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPLEGELPGWVDLL", "length": 351, "header": "tr|A0ABI0NQV0-1|A0ABI0P3P6_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=MAST4 PE=3 SV=1 CANONICAL=A0ABI0P3P6-1" }, "locus": { "chromosome": "20", "start_pos": 12814616, "end_pos": 12502207, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136180.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136180.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104794.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104794.1" } ] } }, { "isoform_ac": "A0ABI0P3L2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6/entry#A0ABI0P3L2-1", "sequence": { "sequence": "MKAQRERLQIPGLTLDLTPRSLSPTPSSPGSPCSPLFAFHFWSCRTSNRKSLIGNGPSPALPRPHSPLSAHAGNSPQDSPRNFSPSASAHFSFARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPYQPTPDELHFLSKHFCTTESITTENRCRNTPMRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDHVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHNRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPLEEMAQLGNYDSGTAETPETDESVSSSNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRCLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHHMETEEEDDTNDEDFNVEIRQFSSCSHRFSKVFSSMDRGTQNSGEEKEDPGDKTKSTALPSTETLSWSSEYSEMQQLSTSNSSDTESNRHRRGAGLLPKLAVSAEAEHDGAAPRPRELHEEPEKPALPAAENAQEEPEVTTPASTISSSTLSDMFAVSPLGSPMSPHSLSSDPSSSRDSSPSRDSSGASASPHQPIVIHSLGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKTGPARRNSYKSRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLHTSRSFSCLNRSLSSGESLPGSPTHSLSPRSPTPSYRSTPDFPSGTNSSQSSSPSSSAPNSPAGSGHVRPSTLHGLAPKLSGQRYRSGRRKSAGSIPLSPLARTPSPTPQPTSPQRSPSPLLGHSLGNSKMAQAFPSKMHSPPTIVRHVVRPKSAEPPRSPLLKRVQSEEKLSPSYGGDKKHLCSRKHSLEVTQEEVPREQQQREVTLQSLEENVCDAPALSRARPVEQGCLKRPVSRKLGRQESVDELDREKLKAKVVVKKPDGLSEKQESRPKPHGLGSDLENLCAFRLEERDKKIYPKASERSNHFESKAAVQEAQPLCSLLKDALHKQANVRASEGVASEGATAAGDHGQGTCDFKRASTHSTLQDGLCHTTHRSTSGKGDTAEKAPQAKEGLRCEKLDGKLANIDYLRKKMSLEDKDESLCSVLKPKVTAGAQDCLPGSLGRPVGGQQEAPPASEARTPFIGSAHAAQLSAVSFVPLKALSGRVDSGAEKPGLAAPESPVRKSPSEYKLEGRSVSCLKPIEGTLDIALLSGPQASKTELPSPEPAQSPSPGSDVESPMPLALPSSTGRKADTAGQRESSPAGFKVNKSYLLEPRFPPASRGLQSSPVVAPPDPELKLDKKVSQAARAPATIMESHPQRGEGHPSQHQDHSPDVKLLPFPGQNLQGANTSRSRSPLLPESVPPREKPSGRELSERGPSIVGSEWSAVRPDIRRDPSKELCPPEAAKPSDNSQTPPVVGRTRLDVSTQTQALEKACGPCGRAKPRDGREEVRLPAREDSSLRSAGAPCERELGAERGLESKMEPASTRWSLEPPRPESEKSGRPSGFQSVQKDGPKEPERKEQPLQKYLTSSQPGPKEPERKEQPLQKHLPSSSQPGPKEPERKEQPLQKHVTSSSQPGPKEPERKEQPLQKHLPSSSQPGPKEPERKEQPLQKHVTSSSQLGPKEPERKEQPLQKHLPSSSQPGPKELERKEQCLQKHLTSSSQLGPKEPEMKEQPPQKHVTSSSQLCPKELERKEQPPQKHLTISSQLSPKEPERKEQPLQEHVTSSSQLSPKEPERKEQCLQKHFTSSSQLGPKEPETKEQPLQKHLTSSSQLSPKEPERKEQLLQEHLTSSSQLSPKEPERKEQCLQKHLTSSSQLGPKEPEMKEQPLQKHLTSSSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTSSCQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQLLQKHLTISSQLSPKEPERKEQLLQKHLTISSQLSPKEPEKKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQLLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQYLQKHLTSSSQLGPKEPETKEQPLQKHLTSSSQVGPKDPERKEQPPQKHLTSKSQPGPKEPERKEQCLQKHLTSSSQPGPKELERKEQPPLKHVTSSSQLGPREPERKEQPPQKHLTSSCQPPPPTKELPGLACQHCILPSHPAASLLGSKPCAIDSSFQDALRPTAVRSDSSSHKPRSDPDLGPPKSKFPDRPLSSQKPSAEAAVSKEPGAPTLGRAGVGSGKGVSEEFPVLPDPQNTAREVIGQGASGYSGPLPMEGGPLDTKLRPTSARCPPEALEMLGHPPGRGLLGASESVDQKLPTFRERQNLSPKAPTPSTVKDCPLPCKQTDRSPSPLATSTNAGKSEGKKCTEALYTPADGEKLGAGLSSVHSEAGPKGTEKPAAAAGKGWPEAKGKGLSPQKPLTEASKPSGMKRSPSATVQSSLRCATLPEKSLSYSCGFPEARPAVPETSTTSSDTSSAKAAGPAAESPASSSRDQQKPLPGGDGRTQMTKSDSLPCFRSSAITLESQHPSPGLVVVTSHRDRALSVTATVGETKGKEPAPTQPAQTRNQNVSREAAKPSPAPSTERPIVLPSEKDTGLRQRRGKESLRGSPHKKAL", "length": 3089, "header": "tr|A0ABI0P3L2-1|A0ABI0P3L2_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=MAST4 PE=3 SV=1 CANONICAL=A0ABI0P3P6-1" }, "locus": { "chromosome": "20", "start_pos": 12672167, "end_pos": 12445002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137638.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137638.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105894.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105894.1" } ] } }, { "isoform_ac": "A0ABI0P3P6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6/entry#A0ABI0P3P6-1", "sequence": { "sequence": "MGEKVSEAPEPVPRGCSSHGAPTPAPAVAAESSPGASSAESSSGSETLSEEGEPGFSREQPPPPPPGGARPAAAWAPALSVPERGVSAPPPRPGGAAPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPGKSLKFKRQLSEDGRHLRRGSLGGALTGRYLLPNPAAGQAWATSAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLIDSQKWNCLVKRCRTSNRKSLIGNGPSPALPRPHSPLSAHAGNSPQDSPRNFSPSASAHFSFARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPYQPTPDELHFLSKHFCTTESITTENRCRNTPMRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDHVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHNRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPLEEMAQLGNYDSGTAETPETDESVSSSNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRCLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHHMETEEEDDTNDEDFNVEIRQFSSCSHRFSKVFSSMDRGTQNSGEEKEDPGDKTKSTALPSTETLSWSSEYSEMQQLSTSNSSDTESNRHRRGAGLLPKLAVSAEAEHDGAAPRPRELHEEPEKPALPAAENAQEEPEVTTPASTISSSTLSDMFAVSPLGSPMSPHSLSSDPSSSRDSSPSRDSSGASASPHQPIVIHSLGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKTGPARRNSYKSRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLHTSRSFSCLNRSLSSGESLPGSPTHSLSPRSPTPSYRSTPDFPSGTNSSQSSSPSSSAPNSPAGSGHVRPSTLHGLAPKLSGQRYRSGRRKSAGSIPLSPLARTPSPTPQPTSPQRSPSPLLGHSLGNSKMAQAFPSKMHSPPTIVRHVVRPKSAEPPRSPLLKRVQSEEKLSPSYGGDKKHLCSRKHSLEVTQEEVPREQQQREVTLQSLEENVCDAPALSRARPVEQGCLKRPVSRKLGRQESVDELDREKLKAKVVVKKPDGLSEKQESRPKPHGLGSDLENLCAFRLEERDKKIYPKASERSNHFESKAAVQEAQPLCSLLKDALHKQANVRASEGVASEGATAAGDHGQGTCDFKRASTHSTLQDGLCHTTHRSTSGKGDTAEKAPQAKEGLRCEKLDGKLANIDYLRKKMSLEDKDESLCSVLKPKVTAGAQDCLPGSLGRPVGGQQEAPPASEARTPFIGSAHAAQLSAVSFVPLKALSGRVDSGAEKPGLAAPESPVRKSPSEYKLEGRSVSCLKPIEGTLDIALLSGPQASKTELPSPEPAQSPSPGSDVESPMPLALPSSTGRKADTAGQRESSPAGFKVNKSYLLEPRFPPASRGLQSSPVVAPPDPELKLDKKVSQAARAPATIMESHPQRGEGHPSQHQDHSPDVKLLPFPGQNLQGANTSRSRSPLLPESVPPREKPSGRELSERGPSIVGSEWSAVRPDIRRDPSKELCPPEAAKPSDNSQTPPVVGRTRLDVSTQTQALEKACGPCGRAKPRDGREEVRLPAREDSSLRSAGAPCERELGAERGLESKMEPASTRWSLEPPRPESEKSGRPSGFQSVQKDGPKEPERKEQPLQKYLTSSQPGPKEPERKEQPLQKHLPSSSQPGPKEPERKEQPLQKHVTSSSQPGPKEPERKEQPLQKHLPSSSQPGPKEPERKEQPLQKHVTSSSQLGPKEPERKEQPLQKHLPSSSQPGPKELERKEQCLQKHLTSSSQLGPKEPEMKEQPPQKHVTSSSQLCPKELERKEQPPQKHLTISSQLSPKEPERKEQPLQEHVTSSSQLSPKEPERKEQCLQKHFTSSSQLGPKEPETKEQPLQKHLTSSSQLSPKEPERKEQLLQEHLTSSSQLSPKEPERKEQCLQKHLTSSSQLGPKEPEMKEQPLQKHLTSSSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTSSCQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQLLQKHLTISSQLSPKEPERKEQLLQKHLTISSQLSPKEPEKKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQLLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQYLQKHLTSSSQLGPKEPETKEQPLQKHLTSSSQVGPKDPERKEQPPQKHLTSKSQPGPKEPERKEQCLQKHLTSSSQPGPKELERKEQPPLKHVTSSSQLGPREPERKEQPPQKHLTSSCQPPPPTKELPGLACQHCILPSHPAASLLGSKPCAIDSSFQDALRPTAVRSDSSSHKPRSDPDLGPPKSKFPDRPLSSQKPSAEAAVSKEPGAPTLGRAGVGSGKGVSEEFPVLPDPQNTAREVIGQGASGYSGPLPMEGGPLDTKLRPTSARCPPEALEMLGHPPGRGLLGASESVDQKLPTFRERQNLSPKAPTPSTVKDCPLPCKQTDRSPSPLATSTNAGKSEGKKCTEALYTPADGEKLGAGLSSVHSEAGPKGTEKPAAAAGKGWPEAKGKGLSPQKPLTEASKPSGMKRSPSATVQSSLRCATLPEKSLSYSCGFPEARPAVPETSTTSSDTSSAKAAGPAAESPASSSRDQQKPLPGGDGRTQMTKSDSLPCFRSSAITLESQHPSPGLVVVTSHRDRALSVTATVGETKGKEPAPTQPAQTRNQNVSREAAKPSPAPSTERPIVLPSEKDTGLRQRRGKESLRGSPHKKAL", "length": 3276, "header": "tr|A0ABI0P3P6-1|A0ABI0P3P6_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=MAST4 PE=3 SV=1 CANONICAL=A0ABI0P3P6-1" }, "locus": { "chromosome": "20", "start_pos": 13060643, "end_pos": 12445002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143627.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143627.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106115.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106115.1" } ] } }, { "isoform_ac": "A0ABI0P499-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6/entry#A0ABI0P499-1", "sequence": { "sequence": "MGEKVSEAPEPVPRGCSSHGAPTPAPAVAAESSPGASSAESSSGSETLSEEGEPGFSREQPPPPPPGGARPAAAWAPALSVPERGVSAPPPRPGGAAPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPGKSLKFKRQLSEDGRHLRRGSLGGALTGRYLLPNPAAGQAWATSAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLCRTSNRKSLIGNGPSPALPRPHSPLSAHAGNSPQDSPRNFSPSASAHFSFARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPYQPTPDELHFLSKHFCTTESITTENRCRNTPMRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDHVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHNRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPLEEMAQLGNYDSGTAETPETDESVSSSNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRCLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHHMETEEEDDTNDEDFNVEIRQFSSCSHRFSKVFSSMDRGTQNSGEEKEDPGDKTKSTALPSTETLSWSSEYSEMQQLSTSNSSDTESNRHRRGAGLLPKLAVSAEAEHDGAAPRPRELHEEPEKPALPAAENAQEEPEVTTPASTISSSTLSDMFAVSPLGSPMSPHSLSSDPSSSRDSSPSRDSSGASASPHQPIVIHSLGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKTGPARRNSYKSRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLHTSRSFSCLNRSLSSGESLPGSPTHSLSPRSPTPSYRSTPDFPSGTNSSQSSSPSSSAPNSPAGSGHVRPSTLHGLAPKLSGQRYRSGRRKSAGSIPLSPLARTPSPTPQPTSPQRSPSPLLGHSLGNSKMAQAFPSKMHSPPTIVRHVVRPKSAEPPRSPLLKRVQSEEKLSPSYGGDKKHLCSRKHSLEVTQEEVPREQQQREVTLQSLEENVCDAPALSRARPVEQGCLKRPVSRKLGRQESVDELDREKLKAKVVVKKPDGLSEKQESRPKPHGLGSDLENLCAFRLEERDKKIYPKASERSNHFESKAAVQEAQPLCSLLKDALHKQANVRASEGVASEGATAAGDHGQGTCDFKRASTHSTLQDGLCHTTHRSTSGKGDTAEKAPQAKEGLRCEKLDGKLANIDYLRKKMSLEDKDESLCSVLKPKVTAGAQDCLPGSLGRPVGGQQEAPPASEARTPFIGSAHAAQLSAVSFVPLKALSGRVDSGAEKPGLAAPESPVRKSPSEYKLEGRSVSCLKPIEGTLDIALLSGPQASKTELPSPEPAQSPSPGSDVESPMPLALPSSTGRKADTAGQRESSPAGFKVNKSYLLEPRFPPASRGLQSSPVVAPPDPELKLDKKVSQAARAPATIMESHPQRGEGHPSQHQDHSPDVKLLPFPGQNLQGANTSRSRSPLLPESVPPREKPSGRELSERGPSIVGSEWSAVRPDIRRDPSKELCPPEAAKPSDNSQTPPVVGRTRLDVSTQTQALEKACGPCGRAKPRDGREEVRLPAREDSSLRSAGAPCERELGAERGLESKMEPASTRWSLEPPRPESEKSGRPSGFQSVQKDGPKEPERKEQPLQKYLTSSQPGPKEPERKEQPLQKHLPSSSQPGPKEPERKEQPLQKHVTSSSQPGPKEPERKEQPLQKHLPSSSQPGPKEPERKEQPLQKHVTSSSQLGPKEPERKEQPLQKHLPSSSQPGPKELERKEQCLQKHLTSSSQLGPKEPEMKEQPPQKHVTSSSQLCPKELERKEQPPQKHLTISSQLSPKEPERKEQPLQEHVTSSSQLSPKEPERKEQCLQKHFTSSSQLGPKEPETKEQPLQKHLTSSSQLSPKEPERKEQLLQEHLTSSSQLSPKEPERKEQCLQKHLTSSSQLGPKEPEMKEQPLQKHLTSSSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTSSCQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQLLQKHLTISSQLSPKEPERKEQLLQKHLTISSQLSPKEPEKKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQLLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQYLQKHLTSSSQLGPKEPETKEQPLQKHLTSSSQPGPKEPERKEQCLQKHLTSSSQPGPKELERKEQPPLKHVTSSSQLGPREPERKEQPPQKHLTSSCQPPPPTKELPGLACQHCILPSHPAASLLGSKPCAIDSSFQDALRPTAVRSDSSSHKPRSDPDLGPPKSKFPDRPLSSQKPSAEAAVSKEPGAPTLGRAGVGSGKGVSEEFPVLPDPQNTAREVIGQGASGYSGPLPMEGGPLDTKLRPTSARCPPEALEMLGHPPGRGLLGASESVDQKLPTFRERQNLSPKAPTPSTVKDCPLPCKQTDRSPSPLATSTNAGKSEGKKCTEALYTPADGEKLGAGLSSVHSEAGPKGTEKPAAAAGKGWPEAKGKGLSPQKPLTEASKPSGMKRSPSATVQSSLRCATLPEKSLSYSCGFPEARPAVPETSTTSSDTSSAKAAGPAAESPASSSRDQQKPLPGGDGRTQMTKSDSLPCFRSSAITLESQHPSPGLVVVTSHRDRALSVTATVGETKGKEPAPTQPAQTRNQNVSREAAKPSPAPSTERPIVLPSEKDTGLRQRRGKESLRGSPHKKAL", "length": 3242, "header": "tr|A0ABI0P499-1|A0ABI0P499_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=MAST4 PE=3 SV=1 CANONICAL=A0ABI0P3P6-1" }, "locus": { "chromosome": "20", "start_pos": 13060643, "end_pos": 12445002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142925.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142925.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105940.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105940.1" } ] } }, { "isoform_ac": "A0ABI0P5U9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6/entry#A0ABI0P5U9-1", "sequence": { "sequence": "MDESSILRRRGLQEGQPPKSHFNSARHRQRLVDPAASKKELSLPRRGSLCRTSNRKSLIGNGPSPALPRPHSPLSAHAGNSPQDSPRNFSPSASAHFSFARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPYQPTPDELHFLSKHFCTTESITTENRCRNTPMRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDHVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHNRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPLEEMAQLGNYDSGTAETPETDESVSSSNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRCLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHHMETEEEDDTNDEDFNVEIRQFSSCSHRFSKVFSSMDRGTQNSGEEKEDPGDKTKSTALPSTETLSWSSEYSEMQQLSTSNSSDTESNRHRRGAGLLPKLAVSAEAEHDGAAPRPRELHEEPEKPALPAAENAQEEPEVTTPASTISSSTLSDMFAVSPLGSPMSPHSLSSDPSSSRDSSPSRDSSGASASPHQPIVIHSLGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKTGPARRNSYKSRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLHTSRSFSCLNRSLSSGESLPGSPTHSLSPRSPTPSYRSTPDFPSGTNSSQSSSPSSSAPNSPAGSGHVRPSTLHGLAPKLSGQRYRSGRRKSAGSIPLSPLARTPSPTPQPTSPQRSPSPLLGHSLGNSKMAQAFPSKMHSPPTIVRHVVRPKSAEPPRSPLLKRVQSEEKLSPSYGGDKKHLCSRKHSLEVTQEEVPREQQQREVTLQSLEENVCDAPALSRARPVEQGCLKRPVSRKLGRQESVDELDREKLKAKVVVKKPDGLSEKQESRPKPHGLGSDLENLCAFRLEERDKKIYPKASERSNHFESKAAVQEAQPLCSLLKDALHKQANVRASEGVASEGATAAGDHGQGTCDFKRASTHSTLQDGLCHTTHRSTSGKGDTAEKAPQAKEGLRCEKLDGKLANIDYLRKKMSLEDKDESLCSVLKPKVTAGAQDCLPGSLGRPVGGQQEAPPASEARTPFIGSAHAAQLSAVSFVPLKALSGRVDSGAEKPGLAAPESPVRKSPSEYKLEGRSVSCLKPIEGTLDIALLSGPQASKTELPSPEPAQSPSPGSDVESPMPLALPSSTGRKADTAGQRESSPAGFKVNKSYLLEPRFPPASRGLQSSPVVAPPDPELKLDKKVSQAARAPATIMESHPQRGEGHPSQHQDHSPDVKLLPFPGQNLQGANTSRSRSPLLPESVPPREKPSGRELSERGPSIVGSEWSAVRPDIRRDPSKELCPPEAAKPSDNSQTPPVVGRTRLDVSTQTQALEKACGPCGRAKPRDGREEVRLPAREDSSLRSAGAPCERELGAERGLESKMEPASTRWSLEPPRPESEKSGRPSGFQSVQKDGPKEPERKEQPLQKYLTSSQPGPKEPERKEQPLQKHLPSSSQPGPKEPERKEQPLQKHVTSSSQPGPKEPERKEQPLQKHLPSSSQPGPKEPERKEQPLQKHVTSSSQLGPKEPERKEQPLQKHLPSSSQPGPKELERKEQCLQKHLTSSSQLGPKEPEMKEQPPQKHVTSSSQLCPKELERKEQPPQKHLTISSQLSPKEPERKEQPLQEHVTSSSQLSPKEPERKEQCLQKHFTSSSQLGPKEPETKEQPLQKHLTSSSQLSPKEPERKEQLLQEHLTSSSQLSPKEPERKEQCLQKHLTSSSQLGPKEPEMKEQPLQKHLTSSSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTSSCQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQLLQKHLTISSQLSPKEPERKEQLLQKHLTISSQLSPKEPEKKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQLLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQYLQKHLTSSSQLGPKEPETKEQPLQKHLTSSSQVGPKDPERKEQPPQKHLTSNSQLGPREPERKEQPPQKHLTSSCQPPPPTKELPGLACQHCILPSHPAASLLGSKPCAIDSSFQDALRPTAVRSDSSSHKPRSDPDLGPPKSKFPDRPLSSQKPSAEAAVSKEPGAPTLGRAGVGSGKGVSEEFPVLPDPQNTAREVIGQGASGYSGPLPMEGGPLDTKLRPTSARCPPEALEMLGHPPGRGLLGASESVDQKLPTFRERQNLSPKAPTPSTVKDCPLPCKQTDRSPSPLATSTNAGKSEGKKCTEALYTPADGEKLGAGLSSVHSEAGPKGTEKPAAAAGKGWPEAKGKGLSPQKPLTEASKPSGMKRSPSATVQSSLRCATLPEKSLSYSCGFPEARPAVPETSTTSSDTSSAKAAGPAAESPASSSRDQQKPLPGGDGRTQMTKSDSLPCFRSSAITLESQHPSPGLVVVTSHRDRALSVTATVGETKGKEPAPTQPAQTRNQNVSREAAKPSPAPSTERPIVLPSEKDTGLRQRRGKESLRGSPHKKAL", "length": 3051, "header": "tr|A0ABI0P5U9-1|A0ABI0P5U9_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=MAST4 PE=3 SV=1 CANONICAL=A0ABI0P3P6-1" }, "locus": { "chromosome": "20", "start_pos": 12814616, "end_pos": 12445002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137640.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137640.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106312.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106312.1" } ] } }, { "isoform_ac": "E1BH93-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6/entry#E1BH93-1", "sequence": { "sequence": "MDMSDPNFWTVLSNFTLPHLRSGNRLRRTQSCRTSNRKSLIGNGPSPALPRPHSPLSAHAGNSPQDSPRNFSPSASAHFSFARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPYQPTPDELHFLSKHFCTTESITTENRCRNTPMRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDHVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHNRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPLEEMAQLGNYDSGTAETPETDESVSSSNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRCLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHHMETEEEDDTNDEDFNVEIRQFSSCSHRFSKVFSSMDRGTQNSGEEKEDPGDKTKSTALPSTETLSWSSEYSEMQQLSTSNSSDTESNRHRRGAGLLPKLAVSAEAEHDGAAPRPRELHEEPEKPALPAAENAQEEPEVTTPASTISSSTLSVGSFSEHLDQINGRSECVDSTDNASKPSNEPASHMARQRLESTEKQKASGKVTKSLSASALSLMIPGDMFAVSPLGSPMSPHSLSSDPSSSRDSSPSRDSSGASASPHQPIVIHSLGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKTGPARRNSYKSRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLHTSRSFSCLNRSLSSGESLPGSPTHSLSPRSPTPSYRSTPDFPSGTNSSQSSSPSSSAPNSPAGSGHVRPSTLHGLAPKLSGQRYRSGRRKSAGSIPLSPLARTPSPTPQPTSPQRSPSPLLGHSLGNSKMAQAFPSKMHSPPTIVRHVVRPKSAEPPRSPLLKRVQSEEKLSPSYGGDKKHLCSRKHSLEVTQEEVPREQQQREVTLQSLEENVCDAPALSRARPVEQGCLKRPVSRKLGRQESVDELDREKLKAKVVVKKPDGLSEKQESRPKPHGLGSDLENLCAFRLEERDKKIYPKASERSNHFESKAAVQEAQPLCSLLKDALHKQANVRASEGVASEGATAAGDHGQGTCDFKRASTHSTLQDGLCHTTHRSTSGKGDTAEKAPQAKEGLRCEKLDGKLANIDYLRKKMSLEDKDESLCSVLKPKVTAGAQDCLPGSLGRPVGGQQEAPPASEARTPFIGSAHAAQLSAVSFVPLKALSGRVDSGAEKPGLAAPESPVRKSPSEYKLEGRSVSCLKPIEGTLDIALLSGPQASKTELPSPEPAQSPSPGSDVESPMPLALPSSTGRKADTAGQRESSPAGFKVNKSYLLEPRFPPASRGLQSSPVVAPPDPELKLDKKVSQAARAPATIMESHPQRGEGHPSQHQDHSPDVKLLPFPGQNLQGANTSRSRSPLLPESVPPREKPSGRELSERGPSIVGSEWSAVRPDIRRDPSKELCPPEAAKPSDNSQTPPVVGRTRLDVSTQTQALEKACGPCGRAKPRDGREEVRLPAREDSSLRSAGAPCERELGAERGLESKMEPASTRWSLEPPRPESEKSGRPSGFQSVQKDGPKEPERKEQPLQKYLTSSQPGPKEPERKEQPLQKHLPSSSQPGPKEPERKEQPLQKHVTSSSQPGPKEPERKEQPLQKHLPSSSQPGPKEPERKEQPLQKHVTSSSQLGPKEPERKEQPLQKHLPSSSQPGPKELERKEQCLQKHLTSSSQLGPKEPEMKEQPPQKHVTSSSQLCPKELERKEQPPQKHLTISSQLSPKEPERKEQPLQEHVTSSSQLSPKEPERKEQCLQKHFTSSSQLGPKEPETKEQPLQKHLTSSSQLSPKEPERKEQLLQEHLTSSSQLSPKEPERKEQCLQKHLTSSSQLGPKEPEMKEQPLQKHLTSSSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTSSCQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQLLQKHLTISSQLSPKEPERKEQLLQKHLTISSQLSPKEPEKKEQPLQKHVTSSSQLSPKEPERKEQPLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQLLQKHLTISSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQPLQKHVTSSSQLSPKEPERKEQYLQKHLTSSSQLGPKEPETKEQPLQKHLTSSSQVGPKDPERKEQPPQKHLTSNSQLGPREPERKEQPPQKHLTSSCQPPPPTKELPGLACQHCILPSHPAASLLGSKPCAIDSSFQDALRPTAVRSDSSSHKPRSDPDLGPPKSKFPDRPLSSQKPSAEAAVSKEPGAPTLGRAGVGSGKGVSEEFPVLPDPQNTAREVIGQGASGYSGPLPMEGGPLDTKLRPTSARCPPEALEMLGHPPGRGLLGASESVDQKLPTFRERQNLSPKAPTPSTVKDCPLPCKQTDRSPSPLATSTNAGKSEGKKCTEALYTPADGEKLGAGLSSVHSEAGPKGTEKPAAAAGKGWPEAKGKGLSPQKPLTEASKPSGMKRSPSATVQSSLRCATLPEKSLSYSCGFPEARPAVPETSTTSSDTSSAKAAGPAAESPASSSRDQQKPLPGGDGRTQMTKSDSLPCFRSSAITLESQHPSPGLVVVTSHRDRALSVTATVGETKGKEPAPTQPAQTRNQNVSREAAKPSPAPSTERPIVLPSEKDTGLRQRRGKESLRGSPHKKAL", "length": 3100, "header": "tr|E1BH93-1|A0ABI0P3P6_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=MAST4 PE=3 SV=4 CANONICAL=A0ABI0P3P6-1" }, "locus": { "chromosome": "20", "start_pos": 12620524, "end_pos": 12445002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036805.6", "url": "https://www.ensembl.org/id/ENSBTAT00000036805.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036658.6", "url": "https://www.ensembl.org/id/ENSBTAP00000036658.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1249, "start_aa": "Thr", "end_pos": 1249, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1249", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1324, "start_aa": "Thr", "end_pos": 1324, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1324", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 23, "start_aa": "Thr", "end_pos": 23, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr23", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2992, "start_aa": "Thr", "end_pos": 2992, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2992", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 326, "start_aa": "Thr", "end_pos": 326, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr326", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3P6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3P6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3P6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3P6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3P6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3P6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3P6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1168, "end_pos": 1170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1226, "end_pos": 1228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1263, "end_pos": 1265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1807, "end_pos": 1809, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1888, "end_pos": 1890, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2985, "end_pos": 2987, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3230, "end_pos": 3232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 965, "end_pos": 967, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", 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"https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP 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"https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LU59", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] } ] }, { "uniprot_ac": "A0A3Q1LW88", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] } ] }, { "uniprot_ac": "A0A3Q1LWT7", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] } ] }, { "uniprot_ac": "A0A3Q1LYH3", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4N6" } ] } ] }, { "uniprot_ac": "A0A3Q1M4X3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4X3" } ] } ] }, { "uniprot_ac": "A0A3Q1M5T5", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M5T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5T5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1M5T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5T5" } ] } ] }, { "uniprot_ac": "A0A3Q1M614", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M614" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M614" } ] } ] }, { "uniprot_ac": "A0A3Q1M6N5", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M6N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6N5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M6N5", "database": "UniProtKB", "url": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] } ] }, { "uniprot_ac": "A0A3Q1MHM3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] } ] }, { "uniprot_ac": "A0A3Q1MI36", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", 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1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": 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"activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": 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"https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532416", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532416", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LXE4", "url": "https://www.orthodb.org/?gene=A0A3Q1LXE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BII2", "url": "https://www.orthodb.org/?gene=E1BII2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178126", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178126", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LXE4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LXE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3T4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3T4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BII2", "url": "https://www.uniprot.org/uniprotkb/E1BII2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BII2-1", "url": "https://www.uniprot.org/uniprotkb/E1BII2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGAAAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIASQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHGVPLPQVSRHQEPIPNGGAAFHCARTYGNKEGQKCSHQDPIESSDSYGDLSDASDLKTPEKQSTNGSFSCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPLGPEGK", "length": 687, "header": "tr|A0ABI0P3T4-1|A0ABI0P3T4_BOVIN Isoform 1 of BTB/POZ domain zinc finger transcription factor OS=Bos taurus OX=9913 GN=PATZ1 PE=4 SV=1 CANONICAL=A0ABI0P3T4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LXE4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3T4/entry#A0A3Q1LXE4-1", "sequence": { "sequence": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGAAAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIASQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQVWVGSSSGLPPLESLPSDLPSWDFAQPALWRSSHSVPDTAFSLSLKKSFPALENLGPAPSSNALFCPAPPGYLRQGWTASEGGRAFTQWPVG", "length": 537, "header": "tr|A0A3Q1LXE4-1|A0ABI0P3T4_BOVIN Computationally mapped isoform of BTB/POZ domain zinc finger transcription factor OS=Bos taurus OX=9913 GN=PATZ1 PE=4 SV=1 CANONICAL=A0ABI0P3T4-1" }, "locus": { "chromosome": "17", "start_pos": 70143421, "end_pos": 70139345, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073718.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073718.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060190.1", "url": "https://www.ensembl.org/id/ENSBTAP00000060190.1" } ] } }, { "isoform_ac": "A0ABI0P3T4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3T4/entry#A0ABI0P3T4-1", "sequence": { "sequence": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGAAAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIASQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHGVPLPQVSRHQEPIPNGGAAFHCARTYGNKEGQKCSHQDPIESSDSYGDLSDASDLKTPEKQSTNGSFSCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPLGPEGK", "length": 687, "header": "tr|A0ABI0P3T4-1|A0ABI0P3T4_BOVIN Isoform 1 of BTB/POZ domain zinc finger transcription factor OS=Bos taurus OX=9913 GN=PATZ1 PE=4 SV=1 CANONICAL=A0ABI0P3T4-1" }, "locus": { "chromosome": "17", "start_pos": 70143421, "end_pos": 70127044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142249.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142249.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105441.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105441.1" } ] } }, { "isoform_ac": "E1BII2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3T4/entry#E1BII2-1", "sequence": { "sequence": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGAAAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIASQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNREGQKCSHQDPIESSDSYGDLSDASDLKTPEKQSTNGSFSCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPLGPEGK", "length": 641, "header": "tr|E1BII2-1|A0ABI0P3T4_BOVIN Computationally mapped isoform of BTB/POZ domain zinc finger transcription factor OS=Bos taurus OX=9913 GN=PATZ1 PE=4 SV=4 CANONICAL=A0ABI0P3T4-1" }, "locus": { "chromosome": "17", "start_pos": 70143421, "end_pos": 70127044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029432.7", "url": "https://www.ensembl.org/id/ENSBTAT00000029432.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029432.6", "url": "https://www.ensembl.org/id/ENSBTAP00000029432.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:532416", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532416", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3T4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3T4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3T4", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3T4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3T4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3T4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3T4" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3T4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3T4" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3T4", "url": 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"structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P3T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3T4" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 130, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P3T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3T4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 292, "end_pos": 314, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P4D0-1", "uniprot_ac": "A0ABI0P4D0", "uniprot_id": "A0ABI0P4D0_BOVIN", "mass": { "chemical_mass": 146041.0, "monoisotopic_mass": 146041.0 }, "refseq": { "ac": "XP_005226005", "name": "WD repeat-containing protein 17 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226005" }, "gene_names": [ { "name": "WDR17", "type": "recommended", "evidence": [ { "id": "A0ABI0P4D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D0" } ] }, { "name": "WDR17", "type": "synonym", "evidence": [ { "id": "XP_005226005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226005" } ] } ], "protein_names": [ { "name": "WD repeat domain 17", "type": "synonym", "evidence": [ { "id": "A0ABI0P4D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D0/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 17 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005226005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226005" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4D0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "WDR17", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D0", "locus": { "chromosome": "27", "start_pos": 7701241, "end_pos": 7631349, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014135", "url": "https://www.ensembl.org/id/ENSBTAG00000014135" } ] } } ], "crossref": [ { "id": "ENSBTAG00000014135", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014135", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "783416", "url": "https://www.ncbi.nlm.nih.gov/gene/783416", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GVFIWDI", "url": "https://omabrowser.org/oma/group/GVFIWDI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR44464", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44464", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44464:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44464:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23774", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23774", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005226005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226005", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5U7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5U7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MED8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MED8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MED8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MED8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQS0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S827", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S827", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S827-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S827-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZH3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZH3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4D0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4D0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B8G0", "url": "https://www.uniprot.org/uniprotkb/E1B8G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B8G0-1", "url": "https://www.uniprot.org/uniprotkb/E1B8G0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWMTYISHWFEQDDWYEGLQRVNMSQVRQVGLLAAGCQPWNRDVCAASGDRFAYCATLAIYVYQLDHHYNEFKLHAIMSEHKKTITALSWCPHNPDLFASGSADNLVIIWNVAEQKVIAKLDSTKGTPASLSWCWNAGDAVAFASHRGPLFIWTISGPDSGVTVHRDAHSFLSDICMFRWHTQKKGKVAFGHVDGSLSIFQPGNKSQKHVLRPDSLEGTDEEDPVSALEWDPLSTDYLLVANLHHGIRLVDSESLCCITTFSFPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPVDNFKLKKTGFHCLHVLNSPPRKKFSNQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGIGLYDMGAKKWDFLRDLGHVETIFDCKFKPDNPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGDLNCIAGATSRNGAFIWDIKKGKMIQRFNEHGKNGIFCIAWSHKDSKRIATCSGDGYCIIRTIDGKILHKYRHPAAVFGCDWSQNNKDMIATGCEDKNVRVYYVATSSDQPLKVFSGHTEKVFHVRWSPLREGTLCSGSDDGSVRIWDYTQDACINILSGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGICLDTVCDHGADVYGLTCHPRRPFTMASCSRDSTVRLWSLTPLITPLQINILADRPWEEILGNTDSAIEQGAPPLLCGKVSRDIKQEIEKLSGNLRVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTSEAQELTTVKMSKFGGGIGVPTKEERLKEAAQIHLRLGQIQRYCELMVELGEWDKALSVAPSVSVKYWKKLMQRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQTFHVSTPKGPSFSDDIYKEDFKELLQEACRELAEWYFQDGRAVLAACCHLAVDNIELAMAYLIRGNELELAVCVGTVLGEPAAPATHYALELLARKCMMIPVWDLAADLLLMTPDSELQLVKLCAFYPGCTEERNDLHEKCKLPTVEECMQLAETAHADGKIFETIKYYLLSQEPEKALPIGIDFIKEHISSSDWTLDTIYPVLDLLSYIRTEKLALHTCTEARNELLILCGYVGALLAIRRQYQSIVPALYEYTSQLLKRRKVSVPLKIEHLSEELDAWRACTQIVNPSSEDSPYTPPSDSQRLVYATLLKRLKEEPLRGIVGPDYVTGSNLPSHSDTHISCLTGLKIQGPVFFLEDGKSTISLNDALMWAKVNPFSPLGTGIRLNPF", "length": 1307, "header": "tr|A0ABI0P4D0-1|A0ABI0P4D0_BOVIN Isoform 1 of WD repeat domain 17 OS=Bos taurus OX=9913 GN=WDR17 PE=4 SV=1 CANONICAL=A0ABI0P4D0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M5U7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D0/entry#A0A3Q1M5U7-1", "sequence": { "sequence": "MSQVRQVGLLAAGCQPWNRDVCAASGDRFAYCATLAIYVYQLDHHYNEFKLHAIMSEHKKTITALSWCPHNPDLFASGSADNLVIIWNVAEQKVIAKLDSTKGTPASLSWCWNAGDAVAFASHRGPLFIWTISGPDSGVTVHRDAHSFLSDICMFRWHTQKKGKVAFGHVDGSLSIFQPGNKSQKHVLRPDSLEGTDEEDPVSALEWDPLSTDYLLVANLHHGIRLVDSESLCCITTFSFPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPVDNFKLKKTGFHCLHVLNSPPRKKFSNQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGIGLYDMGAKKWDFLRDLGHVETIFDCKFKPDNPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGILHFLKHGKNGIFCIAWSHKDSKRIATCSGDGYCIIRTIDGKILHKYRHPAAVFGCDWSQNNKDMIATGCEDKNVRVYYVATSSDQPLKVFSGHTEKVFHVRWSPLREGTLCSGSDDGSVRIWDYTQDACINILSGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGICLDTVCDHGADVYGLTCHPRRPFTMASCSRDSTVRLWSLTPLITPLQINILADRPWEEILGNTDSAIEQGAPPLLCGKVSRDIKQEIEKLSGNLRVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTSEAQELTTVKMSKFGGGIGVPTKEERLKEAAQIHLRLGQIQRYCELMVELGEWDKALSVAPSVSVKYWKKLMQRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQTFHVSTPKGPSFSDDIYKEDFKELLQEACRELAEWYFQDGRAVLAACCHLAVDNIELAMAYLIRGNELELAVCVGTVLGEPAAPATHYALELLARKCMMIPVWDLAADLLLMTPDSELQLVKLCAFYPGCTEERNDLHEKCKLPTVEECMQLAETAHADGKIFETIKYYLLSQEPEKALPIGIDFIKEHISSSDWTLDTIYPVLDLLSYIRTEKLALHTCTEARNELLILCGYVGALLAIRRQYQSIVPALYEYTSQLLKRRKVSVPLKIEHLSEELDAWRACTQIVNPSSEDSPYTPPSDSQRLVYATLLKRLKEEPLRGIVGPDYVTGSNLPSHSDTHISCLTGLKIQGPVFFLEDGKSTISLNDALMWAKVNPFSPLGTGIRLNPF", "length": 1259, "header": "tr|A0A3Q1M5U7-1|A0ABI0P4D0_BOVIN Computationally mapped isoform of WD repeat domain 17 OS=Bos taurus OX=9913 GN=WDR17 PE=4 SV=2 CANONICAL=A0ABI0P4D0-1" }, "locus": { "chromosome": "27", "start_pos": 7700884, "end_pos": 7653371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077182.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077182.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069068.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069068.2" } ] } }, { "isoform_ac": "A0A3Q1MED8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D0/entry#A0A3Q1MED8-1", "sequence": { "sequence": "MAWMTYISHWFEQDDWYEGLQRVNMSQVRQVGLLAAGCQPWNRDVCAASGDRFAYCATLAIYVYQLDHHYNEFKLHAIMSEHKKTITALSWCPHNPDLFASGSADNLVIIWNVAEQKVIAKLDSTKGTPASLSWCWNAGDAVAFASHRGPLFIWTISGPDSGVTVHRDAHSFLSDICMFRWHTQKKGKVAFGHVDGSLSIFQPGNKSQKHVLRPDSLEGTDEEDPVSALEWDPLSTDYLLVANLHHGIRLVDSESLCCITTFSFPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPVDNFKLKKTGFHCLHVLNSPPRKKFSNQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGIGLYDMGAKKWDFLRDLGHVETIFDCKFKPDNPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGDLNCIAGATSRNGAFIWDIKKGKMIQRFNEHGKNGIFCIAWSHKDSKRIATCSGDGYCIIRTIDGKILHKYRHPAAVFGCDWSQNNKDMIATGCEDKNVRVYYVATSSDQPLKVFSGHTEKVFHVRWSPLREGTLCSGSDDGSVRIWDYTQDACINILSGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGICLDTVCDHGADVYGLTCHPRRPFTMASCSRDSTVRLWSLTPLITPLQINILADRPWEEILGNTDSAIEQGAPPLLCGKVSRDIKQEIEKLSGNLRVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTWDKALSVAPSVSVKYWKKLMQRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQTFHVSTPKGPSFSDDIYKEDFKELLQEACRELAEWYFQDGRAVLAACCHLAVDNIELAMAYLIRGNELELAVCVGTVLGEPAAPATHYALELLARKCMMIPVWDLAADLLLMTPDSELQLVKLCAFYPGCTEERNDLHEKCKLPTVEECMQLAETAHADGKIFETIKYYLLSQEPEKALPIGIDFIKEHISSSDWTLDTIYPVLDLLSYIRTEKLALHTCTEARNELLILCGYVGALLAIRRQYQSIVPALYEYTSQLLKRRKVSVPLKIEHLSEELDAWRACTQIVNPSSEDSPYTPPSDSQRLVYATLLKRLKEEPLRGIVGPDYVTGSNLPSHSDTHISCLTGLKIQGPVFFLEDGKSTISLNDALMWAKVNPFSPLGTGIRLNPF", "length": 1255, "header": "tr|A0A3Q1MED8-1|A0ABI0P4D0_BOVIN Computationally mapped isoform of WD repeat domain 17 OS=Bos taurus OX=9913 GN=WDR17 PE=4 SV=1 CANONICAL=A0ABI0P4D0-1" }, "locus": { "chromosome": "27", "start_pos": 7700884, "end_pos": 7646864, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067430.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067430.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067241.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067241.1" } ] } }, { "isoform_ac": "A0A3Q1MQS0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D0/entry#A0A3Q1MQS0-1", "sequence": { "sequence": "MSQVRQVGLLAAGCQPWNRDVCAASGDRFAYCATLAIYVYQLDHHYNEFKLHAIMSEHKKTITALSWCPHNPDLFASGSADNLVIIWNVAEQKVIAKLDSTKGTPASLSWCWNAGDAVAFASHRGPLFIWTISGPDSGVTVHRDAHSFLSDICMFRWHTQKKGKVAFGHVDGSLSIFQPGNKSQKHVLRPDSLEGTDEEDPVSALEWDPLSTDYLLVANLHHGIRLVDSESLCCITTFSFPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPVDNFKLKKTGFHCLHVLNSPPRKKFSNQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGIGLYDMGAKKWDFLRDLGHVETIFDCKFKPDNPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGDLNCIAGATSRNGAFIWDIKKGKMIQRFNEHGKNGIFCIAWSHKDSKRIATCSGDGYCIIRTIDGKILHKYRHPAAVFGCDWSQNNKDMIATGCEDKNVRVYYVATSSDQPLKVFSGHTEKVFHVRWSPLREGTLCSGSDDGSVRIWDYTQDACINILSGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGICLDTVCDHGADVYGLTCHPRRPFTMASCSRDSTVRLWSLTPLITPLQINILADRPWEEILGNTDSAIEQGAPPLLCGKVSRDIKQEIEKLSGNLRVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTSEAQELTTVKMSKFGGGIGVPTKEERLKEAAQIHLRLGQIQRYCELMVELGEWDKALSVAPSVSVKYWKKLMQRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQTFHVSTPKGPSFSDDIYKEDFKELLQEACRELAEWYFQDGRAVLAACCHLAVDNIECKLPTVEECMQLAETAHADGKIFETIKYYLLSQEPEKALPIGIDFIKEHISSSDWTLDTIYPVLDLLSYIRTEKLALHTCTEARNELLILCGYVGALLAIRRQYQSIVPALYEYTSQLLKRRKVSVPLKIEHLSEELDAWRACTQIVNPSSEDSPYTPPSDSQRLVYATLLKRLKEEPLRGIVGPDYVTGSNLPSHSDTHISCLTGLKIQGPVFFLEDGKSTISLNDALMWAKVNPFSPLGTGIRLNPF", "length": 1199, "header": "tr|A0A3Q1MQS0-1|A0ABI0P4D0_BOVIN Computationally mapped isoform of WD repeat domain 17 OS=Bos taurus OX=9913 GN=WDR17 PE=4 SV=1 CANONICAL=A0ABI0P4D0-1" }, "locus": { "chromosome": "27", "start_pos": 7700884, "end_pos": 7653371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082016.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082016.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072127.1", "url": "https://www.ensembl.org/id/ENSBTAP00000072127.1" } ] } }, { "isoform_ac": "A0AAA9S827-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D0/entry#A0AAA9S827-1", "sequence": { "sequence": "MSQVRQVGLLAAGCQPWNRDVCAASGDRFAYCATLAIYVYQLDHHYNEFKLHAIMSEHKKTITALSWCPHNPDLFASGSADNLVIIWNVAEQKVIAKLDSTKGTPASLSWCWNAGDAVAFASHRGPLFIWTISGPDSGVTVHRDAHSFLSDICMFRWHTQKKGKVAFGHVDGSLSIFQPGNKSQKHVLRPDSLEGTDEEDPVSALEWDPLSTDYLLVANLHHGIRLVDSESLCCITTFSFPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPVDNFKLKKTGFHCLHVLNSPPRKKFSNQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGIGLYDMGAKKWDFLRDLGHVETIFDCKFKPDNPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGDLNCIAGATSRNGAFIWDIKKGKMIQRFNEHGKNGIFCIAWSHKDSKRIATCSGDGYCIIRTIDGKILHKYRHPAAVFGCDWSQNNKDMIATGCEDKNVRVYYVATSSDQPLKVFSGHTEKVFHVRWSPLREGTLCSGSDDGSVRIWDYTQDACINILSGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGICLDTVCDHGADVYGCVPSPDSAIEQGAPPLLCGKVSRDIKQEIEKLSGNLRVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTSEAQELTTVKMSKFGGGIGVPTKEERLKEAAQIHLRLGQIQRYCELMVELGEWDKALSVAPSVSVKYWKKLMQRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQTFHVSTPKGPSFSDDIYKEDFKELLQEACRELAEWYFQDGRAVLAACCHLAVDNIELAMAYLIRGNELELAVCVGTVLGEPAAPATHYALELLARKCMMIPVWDLAADLLLMTPDSELQLVKLCAFYPGCTEERNDLHEKCKLPTVEECMQLAETAHADGKIFETIKYYLLSQEPEKALPIGIDFIKEHISSSDWTLDTIYPVLDLLSYIRTEKLALHTCTEARNELLILCGYVGALLAIRRQYQSIVPALYEYTSQLLKRRKVSVPLKIEHLSEELDAWRACTQIVNPSSEDSPYTPPSDSQRLVYATLLKRLKEEPLRGIVGPDYVTGSNLPSHSDTHISCLTGLKIQGPVFFLEDGKSTISLNDALMWAKVNPFSPLGTGIRLNPF", "length": 1239, "header": "tr|A0AAA9S827-1|A0ABI0P4D0_BOVIN Computationally mapped isoform of WD repeat domain 17 OS=Bos taurus OX=9913 GN=WDR17 PE=4 SV=1 CANONICAL=A0ABI0P4D0-1" }, "locus": { "chromosome": "27", "start_pos": 7700884, "end_pos": 7653371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088527.2", "url": "https://www.ensembl.org/id/ENSBTAT00000088527.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080082.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080082.1" } ] } }, { "isoform_ac": "A0AAA9TZH3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D0/entry#A0AAA9TZH3-1", "sequence": { "sequence": "MSQVRQVGLLAAGCQPWNRDVCAASGDRFAYCATLAIYVYQLDHHYNEFKLHAIMSEHKKTITALSWCPHNPDLFASGSADNLVIIWNVAEQKVIAKLDSTKGTPASLSWCWNAGDAVAFASHRGPLFIWTISGPDSGVTVHRDAHSFLSDICMFRWHTQKKGKVAFGHVDGSLSIFQPGNKSQKHVLRPDSLEGTDEEDPVSALEWDPLSTDYLLVANLHHGIRLVDSESLCCITTFSFPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPVDNFKLKKTGFHCLHVLNSPPRKKFSNQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGIGLYDMGAKKWDFLRDLGHVETIFDCKFKPDNPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGDLNCIAGATSRNGAFIWDIKKGKMIQRFNEHGKNGIFCIAWSHKDSKRIATCSGDGYCIIRTIDGKILHKYRHPAAVFGCDWSQNNKDMIATGCEDKNVRVYYVATSSDQPLKVFSGHTEKVFHVRWSPLREGTLCSGSDDGSVRIWDYTQDACINILSGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGICLDTVCDHGADVYGLTCHPRRPFTMASCSRDSTVRLWSLTPLITPLQINILADRPWEEILGNTDSAIEQGAPPLLCGKVSRDIKQEIEKLSGNLRVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTSEAQELTTVKMSKFGGGIGVPTKEERLKEAAQIHLRLGQIQRYCELMVELGEWDKALSVAPSVSVKYWKKLMQRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQTFHVSTPKGPSFSDDIYKEDFKELLQEACRELAEWYFQDGRAVLAACCHLAVDNIELAMAYLIRGNELELAVCVGTVLGEPAAPATHYALELLARKCMMIPVWDLAADLLLMTPDSELQLVKLCAFYPGCTEERNDLHEKCKLPTVEECMQLAETAHADGKIFETIKYYLLSQEPEKALPIGIDFIKEHISSSDWTLDTIYPVLDLLSYIRTEKLALHTCTEARNELLILCGYVGALLAIRRQYQSIVPALYEYTSQLLKRRKVSVPLKIEHLSEELDAWRACTQIVNPSSEDSPYTPPSDSQRLVYATLLKRLKEEPLRGIVGPDYVTGSNLPSHSDTHISCLTGLKIQGPVFFLEDGKSTISLNDALMWAKVNPFSPLGTGIRLNPF", "length": 1283, "header": "tr|A0AAA9TZH3-1|A0ABI0P4D0_BOVIN Computationally mapped isoform of WD repeat domain 17 OS=Bos taurus OX=9913 GN=WDR17 PE=4 SV=2 CANONICAL=A0ABI0P4D0-1" }, "locus": { "chromosome": "27", "start_pos": 7700884, "end_pos": 7653371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117556.2", "url": "https://www.ensembl.org/id/ENSBTAT00000117556.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102972.2", "url": "https://www.ensembl.org/id/ENSBTAP00000102972.2" } ] } }, { "isoform_ac": "A0ABI0P4D0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D0/entry#A0ABI0P4D0-1", "sequence": { "sequence": "MAWMTYISHWFEQDDWYEGLQRVNMSQVRQVGLLAAGCQPWNRDVCAASGDRFAYCATLAIYVYQLDHHYNEFKLHAIMSEHKKTITALSWCPHNPDLFASGSADNLVIIWNVAEQKVIAKLDSTKGTPASLSWCWNAGDAVAFASHRGPLFIWTISGPDSGVTVHRDAHSFLSDICMFRWHTQKKGKVAFGHVDGSLSIFQPGNKSQKHVLRPDSLEGTDEEDPVSALEWDPLSTDYLLVANLHHGIRLVDSESLCCITTFSFPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPVDNFKLKKTGFHCLHVLNSPPRKKFSNQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGIGLYDMGAKKWDFLRDLGHVETIFDCKFKPDNPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGDLNCIAGATSRNGAFIWDIKKGKMIQRFNEHGKNGIFCIAWSHKDSKRIATCSGDGYCIIRTIDGKILHKYRHPAAVFGCDWSQNNKDMIATGCEDKNVRVYYVATSSDQPLKVFSGHTEKVFHVRWSPLREGTLCSGSDDGSVRIWDYTQDACINILSGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGICLDTVCDHGADVYGLTCHPRRPFTMASCSRDSTVRLWSLTPLITPLQINILADRPWEEILGNTDSAIEQGAPPLLCGKVSRDIKQEIEKLSGNLRVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTSEAQELTTVKMSKFGGGIGVPTKEERLKEAAQIHLRLGQIQRYCELMVELGEWDKALSVAPSVSVKYWKKLMQRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQTFHVSTPKGPSFSDDIYKEDFKELLQEACRELAEWYFQDGRAVLAACCHLAVDNIELAMAYLIRGNELELAVCVGTVLGEPAAPATHYALELLARKCMMIPVWDLAADLLLMTPDSELQLVKLCAFYPGCTEERNDLHEKCKLPTVEECMQLAETAHADGKIFETIKYYLLSQEPEKALPIGIDFIKEHISSSDWTLDTIYPVLDLLSYIRTEKLALHTCTEARNELLILCGYVGALLAIRRQYQSIVPALYEYTSQLLKRRKVSVPLKIEHLSEELDAWRACTQIVNPSSEDSPYTPPSDSQRLVYATLLKRLKEEPLRGIVGPDYVTGSNLPSHSDTHISCLTGLKIQGPVFFLEDGKSTISLNDALMWAKVNPFSPLGTGIRLNPF", "length": 1307, "header": "tr|A0ABI0P4D0-1|A0ABI0P4D0_BOVIN Isoform 1 of WD repeat domain 17 OS=Bos taurus OX=9913 GN=WDR17 PE=4 SV=1 CANONICAL=A0ABI0P4D0-1" }, "locus": { "chromosome": "27", "start_pos": 7700884, "end_pos": 7646864, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141330.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141330.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105731.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105731.1" } ] } }, { "isoform_ac": "E1B8G0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D0/entry#E1B8G0-1", "sequence": { "sequence": "MSQVRQVGLLAAGCQPWNRDVCAASGDRFAYCATLAIYVYQLDHHYNEFKLHAIMSEHKKTITALSWCPHNPDLFASGSADNLVIIWNVAEQKVIAKLDSTKGTPASLSWCWNAGDAVAFASHRGPLFIWTISGPDSGVTVHRDAHSFLSDICMFRWHTQKKGKVAFGHVDGSLSIFQPGNKSQKHVLRPDSLEGTDEEDPVSALEWDPLSTDYLLVANLHHGIRLVDSESLCCITTFSFPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPVDNFKLKKTGFHCLHVLNSPPRKKFSNQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGIGLYDMGAKKWDFLRDLGHVETIFDCKFKPDNPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGDLNCIAGATSRNGAFIWDIKKGKMIQRFNEHGKNGIFCIAWSHKDSKRIATCSGDGYCIIRTIDGKILHKYRHPAAVFGCDWSQNNKDMIATGCEDKNVRVYYVATSSDQPLKVFSGHTEKVFHVRWSPLREGTLCSGSDDGSVRIWDYTQDACINILSGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGICLDTVCDHGADVYGLTCHPRRPFTMASCSRDSTVRLWSLTPLITPLQINILADRPWEEILGNTDSAIEQGAPPLLCGKVSRDIKQEIEKLSGNLRVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTSEAQELTTVKMSKFGGGIGVPTKEERLKEAAQIHLRLGQIQRYCELMVELGEWDKALSVAPSVSVKYWKKLMQRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQTFHVSTPKGPSFSDDIYKEDFKELLQEACRELAEWYFQDGRAVLAACCHLAVDNIELAMAYLIRGNELELAVCVGTVLGEPAAPATHYALELLARKCMMIPVWDLAADLLLMTPDSELQLVKLCAFYPGCTEERNDLHEKCKLPTVEECMQLAETAHADGKIFETIKYYLLSQEPEKALPIGIDFIKEHISSSDWTLDTIYPVLDLLSYIRTEKLALHTCTDQLLKRRKVSVPLKIEHLSEELDAWRACTQIVNPSSEDSPYTPPSDSQRLVYATLLKRLKEEPLRGIVGPDYVTGSNLPSHSDTHISCLTGLKIQGPVFFLEDGKSTISLNDALMWAKVNPFSPLGTGIRLNPF", "length": 1249, "header": "tr|E1B8G0-1|A0ABI0P4D0_BOVIN Computationally mapped isoform of WD repeat domain 17 OS=Bos taurus OX=9913 GN=WDR17 PE=4 SV=4 CANONICAL=A0ABI0P4D0-1" }, "locus": { "chromosome": "27", "start_pos": 7700884, "end_pos": 7653371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018791.8", "url": "https://www.ensembl.org/id/ENSBTAT00000018791.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018791.7", "url": "https://www.ensembl.org/id/ENSBTAP00000018791.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A820-1", "protein_name": "WD repeat domain 17", "gene_name": "Wdr17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWMTYVSHWFEQDDWYEGLQRATMSQVRQVGLLAAGCQPWNKDVCAANGDRFAYCATLAIYIYQLDHRYNEFRLHAIMAEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQNVIAKLDNIKETPACLSWCWNTGDAVAFVSQKGPLLIWTISGPDSGVSVHKEAHGFVSDICIFRWHTQKKGKVAFGHTDGSISIFQPGSKNQKHVLRPESLEGTDEDDPVTALEWDPLSTDYLLVANLHYGIRLLDSESLYCITTFSFPSAAVSVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPIDSFKLKKAGFHCLHVVNSPPKRKFSVQSSNKNHYMSSTSEAVPPPSLTRNQAFSLPPGHVVCCFLDGGVGLYDMGAKKWDFLRELGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKGKMIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCIIRTLDGKLLHKYKHPAAVFGCDWSQNNKDMIATGCEDKHVRVFYVASSSNQPLKVFSGHTARVFHVKWSPLREGVLCSGSDDGSVRIWDYTQDACISILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLIPLITPLQINILADRPWEEIIGNTDNAIEQASPPLLCGKASKDIKQEVEKLTCNPRVKKLRLFSECLSSPGGSDNLWNLVAVIKGQDDSLLPQNYYKGMMHLKHLIKFRTSEAQELTTIKMSKFGGGIGAPTKENKLKEAAEIHLRLGQIQRYCELMVELGEWDKALSVAPGVSVKYWRKLMQRRADQLIQEDKDDVIPYCIATGDVKKLVNFFVSRGQLKEALLVAQAACEGNMQSIHVSTPKGASYPDDVYKEDFNELLHKVINELAEWYFQDGRAVLAACCHLAVDDIELAMAYLIRGNELELAVSVGTVLGEPAAPAMHYALQLLARKCMMIPMCFPSVVYSFPFCYTNRNLAVDLLLMTPDREVHLIKLCAFYPGCIEEINDLHKKCNLPPAEECIQLAETAQADGNVYETIKYYLLSQEPEKALPIGIDFVKGCISNSNWTLDTVHPVLDLMTYIRTEKLLLHTCTEARNELLILCGYIGALLAIRRQYHSIVPALYEYTSQLLKRRVVSVPLKIEHLSEELDAWRACTQSTKQLSEDSPYVPPSDSQRTVYETLLKRLKEEPLKGITGPDYVTGTNLPSHSDIHISCLNGLKIQGPVYFLEDGKSAISLNDALMWAKVNPFSPLGTGIRLNPF", "length": 1322 }, "evidence": [ { "id": "A0ABI0P4D0", "url": "https://omabrowser.org/oma/group/A0ABI0P4D0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q271-1", "protein_name": "WD repeat domain 17", "gene_name": "Wdr17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWMTYVSHWFEQDDWYEGLQRATMSQVRQVGLLAAGCQPWNKDVCAANGDRFAYCATLAIYIYQLDHRYNEFKLHAIMSEHKKTITAISWCPHNPDLFASSSTDNLVIIWNVAEQKVIAKLDNIKETPACLGWCWNTHDAVAFVSQKGPLLIWTISGPDSGVSVHKEAHSFASDICIFRWHTQKKGKVAFGHIDGSISIFQPGSKNQKHVLRPDSLEGTDEEDPVTALEWDPLSTDYLLVANLHFGIRLLDSESLYCITTFNLPSAAVSVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNFKLKKTGFHCFHVVNSPPKKKFSVQSPNKNHYISSTSEAVPPPNLTQNQAFSLPPGHVVCCFLDGGVGLYDMGAKKWDFLRELGHVETIFDCKFKPDDPNVLATASFDGTIKVWDINTLTAVYTSPGNEGVIFALSWAPGDLNCIAGATSRNGAFIWDIQKGKIIQRFNEHGKNGIFYIAWSHKDSKRIATCSGDGFCIIRTVDGKLLHKYKHPAAVFGCDWSQNNKDMIATGCEDKNIRVFYVATSSNQPLKVFSGHTARVFHVKWSPLREGILCSGSDDGSVRIWDYTQDACVSTLNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTRGGVCLDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLIPLITPLQINILADRSWDEVIGNTDNAIRQDCPPLLCGKVSRDIKQEVEKLTCNPRAKKLRLFSECLSPPGGSDNLWNLVSVIKGQDDSLLPQNYCKGMMHLKHLIKFRTSEAQELTTIKMSKFGGGVGAPTKEKKLKEAAEIHLRLGQIQRYCELMVELGEWDKALSVAPGVSVKYWRKLMQRRADQLIQEDKDDVIPYCIATGDVKKLVNFFVSRGQLKEALLVAQAACEGNMQNAHVSTPKGASNSDDIHKEDFNELLHKVINELAEWYFQDGQAVLAACCHLAVDDIELAMAYLIRGNELELAVSVGTVLGEPAAPAMHYALQLLATKCMMIPMCFPSVVYSFPLCYTNRNLAADLLLMTPGSEVHLVKLCAFYPGCIEEINDLHKKCNLPPAEECTQLAETARADGNVFETIKYYLLSQEPEKALPIGIDFVKGCISNSNWTLDTVYPVLDLMSYIRTEKLLLHTCTEARNELLILCGYIGALLAIRRQYQSIVPSLYEYTSQLLKRRVVSVPLKIEHLSEELDAWRACTQSTKQSSEDSPYTPPSDSQRTVYETLLKRLKEEPLKGITGLDYVTGSNLPSHSDIHISCLTGLKIQGPVYFLEDGKSTISLNDALMWAKVNPFSPLGTGIRLNPF", "length": 1322 }, "evidence": [ { "id": "A0ABI0P4D0", "url": "https://omabrowser.org/oma/group/A0ABI0P4D0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZU2-1", "protein_name": "WD repeat-containing protein 17", "gene_name": "WDR17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAWMTYISNWFEQDDWYEGLQRANMSQVRQVGLLAAGCQPWNKDVCAASGDRFAYCATLAIYIYQLDHRYNEFKLHAIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNAEDVVAFVSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQKGKVVFGHIDGSLSIFHPGNKNQKHVLRPESLEGTDEEDPVTALEWDPLSTDYLLVVNLHYGIRLVDSESLSCITTFNLPSAAASVQCLAWVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNLKLKKTGFHCLHVLNSPPRKKFSVQSPTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRDLGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTALVTPVQINILADRSWEEIIGNTDYAIEPGTPPLLCGKVSRDIRQEIEKLTANSQVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLPQNYCKGIMHLKHLIKFRTSEAQELTTVKMSKFGGGIGVPAKEERLKEAAEIHLRLGQIQRYCELMVELGEWDKALSIAPGVSVKYWKKLMQRRADQLIQEDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQAACEGNMQPLHVSVPKGASYSDDIYKEDFNELLHKVSKELAEWYFQDGRAVLAACCHLAIDNIELAMAYLIRGNELELAVCVGTVLGESAAPATHYALELLARKCMMISVCFPCVGYSVPFCYVNRNLAADLLLMIPDNELHLIKLCAFYPGCTEEINDLHDKCKLPTVEECMQLAETARADDNIFETVKYYLLSQEPEKALPIGISFVKEYISSSDWTLDTIYPVLDLLSYIRTEKLLLHTCTEARNELLILCGYIGALLAIRRQYQSIVPALYEYTSQLLKRREVSVPLKIEYLSEELDAWRACTQSTNRSLEDSPYTPPSDSQRMIYATLLKRLKEESLKGIIGPDYVTGSNLPSHSDIHISCLTGLKIQGPVFFLEDGKSAISLNDALMWAKVNPFSPLGTGIRLNPF", "length": 1322 }, "evidence": [ { "id": "A0ABI0P4D0", "url": "https://omabrowser.org/oma/group/A0ABI0P4D0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P4D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4D0" }, { "id": "PF23774", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23774" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gem-associated protein 5 TPR", "eco_id": "ECO_0000259", "start_pos": 817, "end_pos": 916, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 }, { "start_pos": 24, "end_pos": 26 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 331, "end_pos": 333 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P177-1", "uniprot_ac": "A0ABI0P177", "uniprot_id": "A0ABI0P177_BOVIN", "mass": { "chemical_mass": 79080.0, "monoisotopic_mass": 79080.0 }, "refseq": {}, "gene_names": [ { "name": "ATXN7", "type": "recommended", "evidence": [ { "id": "A0ABI0P177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177" } ] } ], "protein_names": [ { "name": "Ataxin 7", "type": "synonym", "evidence": [ { "id": "A0ABI0P177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P177", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ATXN7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177", "locus": { "chromosome": "22", "start_pos": 37469886, "end_pos": 37560061, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011287", "url": "https://www.ensembl.org/id/ENSBTAG00000011287" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011287", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011287", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "536833", "url": "https://www.ncbi.nlm.nih.gov/gene/536833", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:536833", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536833", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NNVHTKH", "url": "https://omabrowser.org/oma/group/NNVHTKH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M960", "url": "https://www.orthodb.org/?gene=A0A3Q1M960", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N112", "url": "https://www.orthodb.org/?gene=F1N112", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15117:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15117:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M960", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M960", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M960-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M960-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8Z6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P177", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P177-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N112", "url": "https://www.uniprot.org/uniprotkb/F1N112", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N112-1", "url": "https://www.uniprot.org/uniprotkb/F1N112-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGDKKPPQSSPSSARGLEALPERRHSSSSKPSLAVPPTSVFSFFPSLSKSKGGSGSGSSRSSSGGVLSTSSLSSKLLKSPKEKLQLRGNRPMHPIQQNRVPHGRIMTPSIKVEKIHPKMDGTLLKSAVGPTCPAPVSSSVKPGLNCPSIPKPTLPSPGHILNGKGLPAPPVLEKKSEDYSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKESIRHPDSQQPAQPLRDPHPTPPRTSQEPHQNSHGVIPSESKPFIASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVYESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPVSTRVPHRTNSVPTSHCGVSYLAAATVSPSPVPLSSTCVSPSSKLVPAHGTTLNAQPAASGAVDPVSSMQSRQVSSSSSSPSTPSGLSSVPSSPMARKPQKLKSSKSLRPKDSSGNSTNCHNASSSAGGGSGKKRKNSSPLLVPSSSSSSSSSSSSHSMESFRKNCVAHSGPPHPSAVASAPGISLNCVASRANSVGGRHEQPGCRGTSSGNPCESIKRMSVMVNSGDSTLSLGPFVHQAGGELPVNSHGAYPHSHTPLDKLLGKKRKCSPGSSGVNSSGGSSKPTKVAKLPAVNNVHAKHVGPSPGAPGLTNSSLLHQPKAHP", "length": 751, "header": "tr|A0ABI0P177-1|A0ABI0P177_BOVIN Isoform 1 of Ataxin 7 OS=Bos taurus OX=9913 GN=ATXN7 PE=4 SV=1 CANONICAL=A0ABI0P177-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M960-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177/entry#A0A3Q1M960-1", "sequence": { "sequence": "MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQPPQPQRQPPPPRRLRPEDGGPGAASTSAAAAMATVGERRPLPSPEAMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCREDMPIFGLCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPSLAVPPTSVFSFFPSLSKSKGGSGSGSSRSSSGGVLSTSSLSSKLLKSPKEKLQLRGNRPMHPIQQNRVPHGRIMTPSIKVEKIHPKMDGTLLKSAVGPTCPAPVSSSVKPGLNCPSIPKPTLPSPGHILNGKGLPAPPVLEKKSEDYSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKESIRHPDSQQPAQPLRDPHPTPPRTSQEPHQNSHGVIPSESKPFIASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVYESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPVSTRVPHRTNSVPTSHCGVSYLAAATVSPSPVPLSSTCVSPSSKLVPAHGTTLNAQPAASGAVDPVSSMQSRQVSSSSSSPSTPSGLSSVPSSPMARKPQKLKSSKSLRPKDSSGNSTNCHNASSSAGGGSGKKRKNSSPLLVPSSSSSSSSSSSSHSMESFRKNCVAHSGPPHPSAVASAPGISLNCVASRANSVGGRHEQPGCRGTSSGNPCESIKRMSVMVNSGDSTLSLGPFVHQAGGELPVNSHGAYPHSHTPLDKLLGKKRKCSPGSSGVNSSGGSSKPTKVAKLPAVNNVHAKHVGPSPGAPGLTNSSLLHQVGQGLGAPWGGSWPLP", "length": 897, "header": "tr|A0A3Q1M960-1|A0ABI0P177_BOVIN Computationally mapped isoform of Ataxin 7 OS=Bos taurus OX=9913 GN=ATXN7 PE=4 SV=2 CANONICAL=A0ABI0P177-1" }, "locus": { "chromosome": "22", "start_pos": 37558390, "end_pos": 37473319, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085416.3", "url": "https://www.ensembl.org/id/ENSBTAT00000085416.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070486.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070486.2" } ] } }, { "isoform_ac": "A0AAA9T8Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177/entry#A0AAA9T8Z6-1", "sequence": { "sequence": "MWSATVSSTSGAERMSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQPPQPQRQPPPPRRLRPEDGGPGAASTSAAAAMATVGERRPLPSPEAMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCREDMPIFGLCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPSLAVPPTSVFSFFPSLSKSKGGSGSGSSRSSSGGVLSTSSLSSKLLKSPKEKLQLRGNRPMHPIQQNRVPHGRIMTPSIKVEKIHPKMDGTLLKSAVGPTCPAPVSSSVKPGLNCPSIPKPTLPSPGHILNGKGLPAPPVLEKKSEDYSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKESIRHPDSQQPAQPLRDPHPTPPRTSQEPHQNSHGVIPSESKPFIASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVYESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPVSTRVPHRTNSVPTSHCGVSYLAAATVSPSPVPLSSTCVSPSSKLVPAHGTTLNAQPAASGAVDPVSSMQSRQVSSSSSSPSTPSGLSSVPSSPMARKPQKLKSSKSLRPKDSSGNSTNCHNASSSAGGGSGKKRKNSSPLLVPSSSSSSSSSSSSHSMESFRKNCVAHSGPPHPSAVASAPGISLNCVASRANSVGGRHEQPGCRGTSSGNPCESIKRMSVMVNSGDSTLSLGPFVHQAGGELPVNSHGAYPHSHTPLDKLLGKKRKCSPGSSGVNSSGGSSKPTKVAKLPAVNNVHAKHVGPSPGAPGLTNSSLLHQVGQGLGAPWGGSWPLP", "length": 911, "header": "tr|A0AAA9T8Z6-1|A0ABI0P177_BOVIN Computationally mapped isoform of Ataxin 7 OS=Bos taurus OX=9913 GN=ATXN7 PE=4 SV=1 CANONICAL=A0ABI0P177-1" }, "locus": { "chromosome": "22", "start_pos": 37559797, "end_pos": 37473319, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087570.1", "url": "https://www.ensembl.org/id/ENSBTAT00000087570.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093090.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093090.1" } ] } }, { "isoform_ac": "A0ABI0P177-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177/entry#A0ABI0P177-1", "sequence": { "sequence": "MEGDKKPPQSSPSSARGLEALPERRHSSSSKPSLAVPPTSVFSFFPSLSKSKGGSGSGSSRSSSGGVLSTSSLSSKLLKSPKEKLQLRGNRPMHPIQQNRVPHGRIMTPSIKVEKIHPKMDGTLLKSAVGPTCPAPVSSSVKPGLNCPSIPKPTLPSPGHILNGKGLPAPPVLEKKSEDYSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKESIRHPDSQQPAQPLRDPHPTPPRTSQEPHQNSHGVIPSESKPFIASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVYESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPVSTRVPHRTNSVPTSHCGVSYLAAATVSPSPVPLSSTCVSPSSKLVPAHGTTLNAQPAASGAVDPVSSMQSRQVSSSSSSPSTPSGLSSVPSSPMARKPQKLKSSKSLRPKDSSGNSTNCHNASSSAGGGSGKKRKNSSPLLVPSSSSSSSSSSSSHSMESFRKNCVAHSGPPHPSAVASAPGISLNCVASRANSVGGRHEQPGCRGTSSGNPCESIKRMSVMVNSGDSTLSLGPFVHQAGGELPVNSHGAYPHSHTPLDKLLGKKRKCSPGSSGVNSSGGSSKPTKVAKLPAVNNVHAKHVGPSPGAPGLTNSSLLHQPKAHP", "length": 751, "header": "tr|A0ABI0P177-1|A0ABI0P177_BOVIN Isoform 1 of Ataxin 7 OS=Bos taurus OX=9913 GN=ATXN7 PE=4 SV=1 CANONICAL=A0ABI0P177-1" }, "locus": { "chromosome": "22", "start_pos": 37500545, "end_pos": 37470890, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146846.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146846.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104345.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104345.1" } ] } }, { "isoform_ac": "F1N112-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177/entry#F1N112-1", "sequence": { "sequence": "MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQPPQPQRQPPPPRRLRPEDGGPGAASTSAAAAMATVGERRPLPSPEAMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCREDMPIFGLCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPSLAVPPTSVFSFFPSLSKSKGGSGSGSSRSSSGGVLSTSSLSSKLLKSPKEKLQLRGNRPMHPIQQNRVPHGRIMTPSIKVEKIHPKMDGTLLKSAVGPTCPAPVSSSVKPGLNCPSIPKPTLPSPGHILNGKGLPAPPVLEKKSEDYSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKESIRHPDSQQPAQPLRDPHPTPPRTSQEPHQNSHGVIPSESKPFIASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVYESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPVSTRVPHRTNSVPTSHCGVSYLAAATVSPSPVPLSSTCVSPSSKLVPAHGTTLNAQPAASGAVDPVSSMQSRQVSSSSSSPSTPSGLSSVPSSPMARKPQKLKSSKSLRPKDSSGNSTNCHNASSSAGGGSGKKRKNSSPLLVPSSSSSSSSSSSSHSMESFRKNCVAHSGPPHPSAVASAPGISLNCVASRANSVGGRHEQPGCRGTSSGNPCESIKRMSVMVNSGDSTLSLGPFVHQAGGELPVNSHGAYPHSHTPLDKLLGKKRKCSPGSSGVNSSGGSSKPTKVAKLPAVNNVHAKHVGPSPGAPGLTNSSLLHQPKAHP", "length": 886, "header": "tr|F1N112-1|A0ABI0P177_BOVIN Computationally mapped isoform of Ataxin 7 OS=Bos taurus OX=9913 GN=ATXN7 PE=4 SV=3 CANONICAL=A0ABI0P177-1" }, "locus": { "chromosome": "22", "start_pos": 37558390, "end_pos": 37470890, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014996.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014996.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014996.6", "url": "https://www.ensembl.org/id/ENSBTAP00000014996.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 132, "start_aa": "Thr", "end_pos": 132, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr132", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 272, "start_aa": "Thr", "end_pos": 272, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr272", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 510, "start_aa": "Thr", "end_pos": 510, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr510", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:536833", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536833", "resource": "KEGG Pathway" }, { "id": "R-BTA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G445-1", "protein_name": "Ataxin 7", "gene_name": "Atxn7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTPGLTPGRHFHTCPWQLWFLGVRTVAASHSCSSYCAAACEPRAKRWCRGSGGRAWATLSSLRRGRPAGSSIGGCVSDFALAPLRGLDVQTSPERAEREGPARGRRRQEAPPLKGAGRAPPLGRTRGRKEGAGLRAGPGCERPQGAERMSERAADDVRGEPRRAAGGAAAARQQQQPQPLQLQRQHPPPRRPRPEDGGTGAATTSAAAMATVGERRPLPSPEAMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCREDMPIFGLCPAHDDFYLVVCNDCNQVVKPQAFQSHCERRHSSSSKPPLAVPRTSVFSLFPSLSKSKAGGAGGSSRPPGGGVLCASSSSKLLRLPKEKLQLRANMKPMHPMQQTKVPHGRVSMTPSVKVEKMHPKMDGALLRSTVGPACPAPVSSAVKPGLSCPSIPKPTLPSPGQTLNGKGLPAMPTLEKKPEDSSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNRTREKELIRHPDCQQLPHPLRDPHPTPPRTLPEPHLPAESKPSLASKPKPHTPSLPRPPGCPAQQGGSTPVDPPPGRESPHPPLPATEPASRLSSEEGEGDDREEPVEKLDCHYSGRHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPCSTSPVSARVPHRTNSVPTPQGGVSSLAAATVSAPAVVLPSSCVSPNSKSAPAHGTTLNAQPAVSGAMDPVCSMQSRHVSASSSSPSTPSGLSSVPSSPLSRKPQKLKPSKSVRPKEPSAVSTNCHSASSSTSGGLGKKRKNSSPLSVHSSSSSASSSSSSHSVDFFRKNCVAHSGTPYLSTAPSSHSIGLNCVTNKTHSVSLRHEPVGRGPAGVSPAESIKRMSVMVNSGDSTLSLGPFVHQSSELPVSPHSHTPLDKLIGKKRKCSPGSSTVGSSGSKPTKVARSPAMNSVHMKHTGTIPGPQGLMNNSLLHQDIFSPCLRTGIAAAAPQSPDLKTKGTTLTADSTTGRNNPDIFEDKLHLCSALWTPRCL", "length": 1069 }, "evidence": [ { "id": "A0ABI0P177", "url": "https://omabrowser.org/oma/group/A0ABI0P177/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C712-1", "protein_name": "Ataxin 7", "gene_name": "ATXN7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSARAAGDVRREQRRAAAARQRQRRPRHGEGGAGGGGGSGAGPAATAAAMAAVGERRSLPSPEAMLGQPWSHWVDAAKLHGNDGTALEESFKEYGKNREAMRLCREDMPIFGLCPAHDDFYLVMCNHCNQVVKPQAFQSHYERRHSSSSKPPLTPPSSSVFSLISSFPSKNKGSGGSGSNRSSSGGTSASSSSSSSKLLKSPKDKLQISGNNRLMHPVQHSKVPHDKIMTPSVKVEKIHPKIDGAQLKAAVGPTCSTTVSSSIKTGLNCPSIPKPPLPSPGQILNGKGLLSVPPFLEKKPEENTNNRKFLHKRLSEREFDPDIYCGVIDVETKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKSKTREKELLRHSDHHQQMPPLREPHPSPTKTSQELHQNSHGVTLTESKPLLPNKPKPHPPSLPRPPGCPAQHSGNAPSDSPSVHESPHPPLPAAEPASRLSSDEGECDEKEEPVEKLDCHYSGHHPQPAAFCTFGSRQIGRGYYVFDKRWNHIRCALNFMVEKHLNSQMWKKIPPASSSTAAVRAPHRTNAMPASQYGVSTTGFLLPTTVMSSPALVSPSCTSLNNKSVPSHGTTLNANPATLGAVDPVCSMQSRQVSSSPSTPTVLSSVPSPMPSKPQKLKSSKSFKPKESSAGSGTCNSTGSVSSGSGSGKKRKNSSALLAPSHSTESFRKNCVVNSGNSGTSYHPSVTSSSHSVGLNCMTSKANSVSLKHDQSGRGPPTGSPAESIKRMSVMMNSSDSTLSLGPFVHQSSELTVNSHSGFSHSHPSLDKLIGKKRKCPPGSSSINSSSSSKSNKVAKLPSVNNVHAKHTGAIPGTQGLMNNSLLHQVGTFVLK", "length": 864 }, "evidence": [ { "id": "A0ABI0P177", "url": "https://omabrowser.org/oma/group/A0ABI0P177/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7F640-1", "protein_name": "Ataxin-7 isoform X1", "gene_name": "atxn7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSERADDDVRGEQQQQQRRAARQLKQQPHFQRGEASTAMATVAERRSLPSPEIMLGQPWSSWVDAVKLYGSDGTELEESLKECGKNREAMRLCRDDMPIFGQCPAQDDFYLVMCSHCSQVVKPQAFQAHYERRHSSSSKPPSSYASSPAFANSRSKGSLGGSGSTLARPSSANSSVPTKIFKSTKEKLPHRKPHFPFRVPSEESQIPTVKVEKVHLKVESSAKLPHVPASSSTFSSSSSSSNTVSTSPLKSGLNFPSIPKAPQLAPGQIPNGKGHQSSQDKKQDNASSRRPLYKRQEREFNPDIHCGVMDMTARKPCTRSLTCKSHSISQRRAVLGRRQRFDTLLAEHKSKTRDKELQFRLDPSHPAPPLRDPHPPPSRLSQDPHPVPHGNGTADATKPLPPNKPKPHNSGLPRINSSNSHSGGDPAMAHDQAHHSHPAPVGPETSRVSSDEGENEDREEATEKLDCHYSGYHPRPAAYCTFGSRLYGRGCFAFDRRWDQVRCALTTMLDKHVNSQMWKKIPLALENSTTAPSASHRTSTNSHSSSSSSVSSGFLGLSSPPPYDSKPVLSYGTTLNARSSPQASATEQPAYSGSSRQVSASSPQMPSAHSSSLPSLGSNRTPKSRSGTKSFRAREPSSSLSNSIIKGSTNSSVSVSSSASSSLSAGKKRKTSSLLTSHSTYTSESSSSFKKNCTINSGSVGSAYHSSLASTPSSTSSSSSTTSSSHSGVYSVGVNCTPGRANSLSLKQESTGRGPPSGSPAESIKRMSVVMNSSDSTLSLGPFVHQSSDHHTDARLEAKRRKGSPGSSSLNSTASGTGVGGGQGPGRPKMAKSPSINNIHSKHARSIPGPPGLPNNSLIHQPKARP", "length": 866 }, "evidence": [ { "id": "A0ABI0P177", "url": "https://omabrowser.org/oma/group/A0ABI0P177/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O15265-1", "protein_name": "Ataxin-7", "gene_name": "ATXN7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPEDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQPKARP", "length": 892 }, "evidence": [ { "id": "A0ABI0P177", "url": "https://omabrowser.org/oma/group/A0ABI0P177/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R4I1-1", "protein_name": "Ataxin-7", "gene_name": "Atxn7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSERAADDVRGEPRRAAGGAAAARQQQQQPQPLQPQRQHPPLRRPRAEDGGTGDTTTSAAAMATVGERRPLPSPEAMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCREDMPIFGLCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPALAVPHTSVFSLLPSLSKSKGSGAGGSSRPPSGGVLCASSSSKLLRLPKEKLPLRGNMKPMHPVQQIKVPHGRVMTPSVKVEKMHPKMDGTLLKSTVGPACPATMSSAVKPGLNCPSIPKPTLPSPGQILNGKGLPAMPTLEKKSEDSSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKAREKELIRHDSQQVPHPLRDPHPTPPRTPQEPQLPAESKPFLASKPKPQTPSLPRPPGCPAQQGGSTPIDPPPGQESPHPPLPATEPASRLSSEEGEGDDREESVEKLDCHYSGRHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPCTTSPVSARVPHRTNSVPTSQGGISYLAATTVSAPPVLLSSTCISPNSKSVPAHGTTLNAQPAGSGAMDPVCSVQSRQVSASSSPPSTPSGLSSVPSSPLSRKPQKWKPSKSIRPKESSALSTNCHNASSSTSGGSGKKRKNSSPLLVPSSSSSSSSSSSSSHSVNSFRKNCVAHSGTPYLSTAPSSHSIGLNCVTNKTHSVSLRHEQAGRGPAGVSSAEPIKRMSVMVNSSDSTLSLGPFIHQASELPVNPHSHTPLDKLIGKKRKCSPGSSTVGNSGSKPTKVAKLPAMNNVHMKHTGNISGAQGLTNNSLLHQPKARP", "length": 867 }, "evidence": [ { "id": "A0ABI0P177", "url": "https://omabrowser.org/oma/group/A0ABI0P177/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P177", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P177", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P177", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P177", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P177", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P177", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 549, "end_pos": 551, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 704, "end_pos": 706, "annotation": "n_glycosylation_sequon" }, { "start_pos": 740, "end_pos": 742, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P177", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P177" }, { "id": "PS51505", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51505" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCA7", "eco_id": "ECO_0000259", "start_pos": 189, "end_pos": 256, "start_aa": "Lys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 132, 272, 510 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 246, "end_pos": 248 }, { "start_pos": 543, "end_pos": 545 }, { "start_pos": 549, "end_pos": 551 }, { "start_pos": 564, "end_pos": 566 }, { "start_pos": 704, "end_pos": 706 }, { "start_pos": 740, "end_pos": 742 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P1M0-1", "uniprot_ac": "A0ABI0P1M0", "uniprot_id": "A0ABI0P1M0_BOVIN", "mass": { "chemical_mass": 149737.0, "monoisotopic_mass": 149737.0 }, "refseq": { "ac": "XP_005218040", "name": "lysine-specific demethylase 2B isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218040" }, "gene_names": [ { "name": "KDM2B", "type": "recommended", "evidence": [ { "id": "A0ABI0P1M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ] }, { "name": "KDM2B", "type": "synonym", "evidence": [ { "id": "XP_005218040", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218040" } ] } ], "protein_names": [ { "name": "Lysine-specific demethylase 2B", "type": "recommended", "evidence": [ { "id": "A0ABI0P1M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0/entry#names_and_taxonomy" } ] }, { "name": "1.14.11.27", "type": "synonym", "evidence": [ { "id": "A0ABI0P1M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0/entry#names_and_taxonomy" } ] }, { "name": "F-box and leucine-rich repeat protein 10", "type": "synonym", "evidence": [ { "id": "A0ABI0P1M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0/entry#names_and_taxonomy" } ] }, { "name": "F-box protein FBL10", "type": "synonym", "evidence": [ { "id": "A0ABI0P1M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0/entry#names_and_taxonomy" } ] }, { "name": "F-box/LRR-repeat protein 10", "type": "synonym", "evidence": [ { "id": "A0ABI0P1M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0/entry#names_and_taxonomy" } ] }, { "name": "JmjC domain-containing histone demethylation protein 1B", "type": "synonym", "evidence": [ { "id": "A0ABI0P1M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0/entry#names_and_taxonomy" } ] }, { "name": "[Histone-H3]-lysine-36 demethylase 1B", "type": "synonym", "evidence": [ { "id": "A0ABI0P1M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0/entry#names_and_taxonomy" } ] }, { "name": "lysine-specific demethylase 2B isoform X6", "type": "synonym", "evidence": [ { "id": "XP_005218040", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218040" } ] } ], "function": [ { "annotation": "Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' and dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NWG6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG6#function" }, { "database": "UniProtKB", "id": "ARBA00056806", "url": "https://www.uniprot.org/uniprotkb/ARBA00056806#function" }, { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0#function" }, { "database": "UniProtKB", "id": "E1BLZ5", "url": "https://www.uniprot.org/uniprotkb/E1BLZ5#function" }, { "database": "UniProtKB", "id": "A0A3Q1MBZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBZ8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KDM2B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0", "locus": { "chromosome": "17", "start_pos": 53769689, "end_pos": 53743010, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002328", "url": "https://www.ensembl.org/id/ENSBTAG00000002328" } ] } } ], "crossref": [ { "id": "ENSBTAG00000002328", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002328", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15644", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15644", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21785", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21785", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22180", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22180", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "614487", "url": "https://www.ncbi.nlm.nih.gov/gene/614487", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041667", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041667", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614487", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614487", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR23123", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23123", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16866", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16866", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17811", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17811", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3214842", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214842", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005218040", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218040", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "42032", "url": "https://www.rhea-db.org/rhea/42032", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MBZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MBZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVY8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWG6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWG6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1M0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLZ5", "url": "https://www.uniprot.org/uniprotkb/E1BLZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BLZ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BLZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAEKDSGRRLRPIDRQRYDENEDLSDVEEIVSARGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREALRVPLVFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCMTQRSYLTQEYQRESMLIDAPRKPSIDGFSSDSWLEMEEESCEQQPQEEKEEEEEEEEEEEGADKTPRASTDGPASPTSTPSEDQEAPGKKPKAPAMRFLKRTLSNESEDSVKSATMPTDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEHAEDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHPKKVPPDGILRRKSDDVHLRRKRKYEKPQELSGRKRASTLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRITLANKPLRRFKQEPEDDLPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSKELSKELNQEIQKTESSLAQENHQPIKSEPESENEEPKRPLGLCERPHRFSKGLNGTPRELRHQLGPGLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCKTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSVSVQFGQVEEKLLQKLS", "length": 1309, "header": "tr|A0ABI0P1M0-1|A0ABI0P1M0_BOVIN Isoform 1 of Lysine-specific demethylase 2B OS=Bos taurus OX=9913 GN=KDM2B PE=3 SV=1 CANONICAL=A0ABI0P1M0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MBZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0/entry#A0A3Q1MBZ8-1", "sequence": { "sequence": "MQKEASSLLLQSLRPIDRQRYDENEDLSDVEEIVSARGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREALRVPLVFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCMTQRSYLTQEYQRESMLIDAPRKPSIDGFSSDSWLEMEEESCEQQPQEEKEEEEEEEEEEEGADKTPRASTDGPASPTSTPSEDQEAPGKKPKAPAMRFLKRTLSNESEDSVKSATMPTDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEHAEDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAGTVPPAPGREWRSPCSPGTAGSAGGSRPPAQPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHPKKVPPDGILRRKSDDVHLRRKRKYEKPQELSGRKRASTLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRITLANKPLRRFKQEPEDDLPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSKELSKELNQEIQKTESSLAQENHQPIKSEPESENEEPKRPLGLCERPHRFSKGLNGTPRELRHQLGPGLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCKTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSVSVQFGQVEEKLLQKLS", "length": 1342, "header": "tr|A0A3Q1MBZ8-1|A0ABI0P1M0_BOVIN Computationally mapped isoform of Lysine-specific demethylase 2B OS=Bos taurus OX=9913 GN=KDM2B PE=3 SV=3 CANONICAL=A0ABI0P1M0-1" }, "locus": { "chromosome": "17", "start_pos": 53768564, "end_pos": 53651447, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086208.3", "url": "https://www.ensembl.org/id/ENSBTAT00000086208.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068303.3", "url": "https://www.ensembl.org/id/ENSBTAP00000068303.3" } ] } }, { "isoform_ac": "A0AAA9TVY8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0/entry#A0AAA9TVY8-1", "sequence": { "sequence": "MEAEKDSGRRLRPIDRQRYDENEDLSDVEEIVSARGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREALRVPLVFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTREKNNF", "length": 323, "header": "tr|A0AAA9TVY8-1|A0ABI0P1M0_BOVIN Computationally mapped isoform of Lysine-specific demethylase 2B OS=Bos taurus OX=9913 GN=KDM2B PE=3 SV=1 CANONICAL=A0ABI0P1M0-1" }, "locus": { "chromosome": "17", "start_pos": 53702195, "end_pos": 53651274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135531.2", "url": "https://www.ensembl.org/id/ENSBTAT00000135531.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101584.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101584.1" } ] } }, { "isoform_ac": "A0ABI0NWG6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0/entry#A0ABI0NWG6-1", "sequence": { "sequence": "MEAEKDSGRRLRPIDRQRYDENEDLSDVEEIVSARGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREALRVPLVFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCMTQRSYLTQEYQRESMLIDAPRKPSIDGFSSDSWLEMEEESCEQQPQEEKEEEEEEEEEEEGADKTPRASTDGPASPTSTPSEDQEAPGKKPKAPAMRFLKRTLSNESEDSVKSATMPTDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEHAEDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAGTVPPAPGREWRSPCSPGTAGSAGGSRPPAQPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHPKKVPPDGILRRKSDDVHLRRKRKYEKPQELSGRKRASTLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRITLANKPLRRFKQEPEDDLPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSKELSKELNQEIQKTESSLAQENHQPIKSEPESENEEPKRPLGLCERPHRFSKGLNGTPRELRHQLGPGLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCKTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSVSVQFGQVEEKLLQKLS", "length": 1340, "header": "tr|A0ABI0NWG6-1|A0ABI0P1M0_BOVIN Computationally mapped isoform of Lysine-specific demethylase 2B OS=Bos taurus OX=9913 GN=KDM2B PE=3 SV=1 CANONICAL=A0ABI0P1M0-1" }, "locus": { "chromosome": "17", "start_pos": 53768564, "end_pos": 53651274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143957.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143957.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104885.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104885.1" } ] } }, { "isoform_ac": "A0ABI0P1M0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0/entry#A0ABI0P1M0-1", "sequence": { "sequence": "MEAEKDSGRRLRPIDRQRYDENEDLSDVEEIVSARGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREALRVPLVFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCMTQRSYLTQEYQRESMLIDAPRKPSIDGFSSDSWLEMEEESCEQQPQEEKEEEEEEEEEEEGADKTPRASTDGPASPTSTPSEDQEAPGKKPKAPAMRFLKRTLSNESEDSVKSATMPTDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEHAEDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHPKKVPPDGILRRKSDDVHLRRKRKYEKPQELSGRKRASTLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRITLANKPLRRFKQEPEDDLPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSKELSKELNQEIQKTESSLAQENHQPIKSEPESENEEPKRPLGLCERPHRFSKGLNGTPRELRHQLGPGLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCKTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSVSVQFGQVEEKLLQKLS", "length": 1309, "header": "tr|A0ABI0P1M0-1|A0ABI0P1M0_BOVIN Isoform 1 of Lysine-specific demethylase 2B OS=Bos taurus OX=9913 GN=KDM2B PE=3 SV=1 CANONICAL=A0ABI0P1M0-1" }, "locus": { "chromosome": "17", "start_pos": 53768564, "end_pos": 53651274, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150072.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150072.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104294.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104294.1" } ] } }, { "isoform_ac": "E1BLZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0/entry#E1BLZ5-1", "sequence": { "sequence": "MRTLLPASSMGLQILPDFNYEYVQREALRVPLVFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCMTQRSYLTQEYQRESMLIDAPRKPSIDGFSSDSWLEMEEESCEQQPQEEKEEEEEEEEEEEGADKTPRASTDGPASPTSTPSEDQEAPGKKPKAPAMRFLKRTLSNESEDSVKSATMPTDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEHAEDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHPKKVPPDGILRRKSDDVHLRRKRKYEKPQELSGRKRASTLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRITLANKPLRRFKQEPEDDLPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSKELSKELNQEIQKTESSLAQENHQPIKSEPESENEEPKRPLGLCERPHRFSKGLNGTPRELRHQLGPGLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCKTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSVSVQFGQVEEKLLQKLS", "length": 1266, "header": "tr|E1BLZ5-1|A0ABI0P1M0_BOVIN Computationally mapped isoform of Lysine-specific demethylase 2B OS=Bos taurus OX=9913 GN=KDM2B PE=3 SV=4 CANONICAL=A0ABI0P1M0-1" }, "locus": { "chromosome": "17", "start_pos": 53768564, "end_pos": 53655017, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003003.8", "url": "https://www.ensembl.org/id/ENSBTAT00000003003.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003003.8", "url": "https://www.ensembl.org/id/ENSBTAP00000003003.8" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 131, "start_aa": "Thr", "end_pos": 131, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr131", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 422, "start_aa": "Thr", "end_pos": 422, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr422", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:614487", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614487", "resource": "KEGG Pathway" }, { "id": "R-BTA-3214842", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214842", "resource": "Reactome", "description": "HDMs demethylate histones" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "midbrain-hindbrain boundary morphogenesis", "id": "GO:0021555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021555", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "fourth ventricle development", "id": "GO:0021592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021592", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "initiation of neural tube closure", "id": "GO:0021993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021993", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "lateral ventricle development", "id": "GO:0021670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021670", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "embryonic camera-type eye morphogenesis", "id": "GO:0048596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048596", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "third ventricle development", "id": "GO:0021678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021678", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "negative regulation of neural precursor cell proliferation", "id": "GO:2000178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000178", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "midbrain development", "id": "GO:0030901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030901", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "unmethylated CpG binding", "id": "GO:0045322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045322", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "histone H3K36me/H3K36me2 demethylase activity", "id": "GO:0140680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140680", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" }, { "name": "histone demethylase activity", "id": "GO:0032452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032452", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1108, "end_pos": 1110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1181, "end_pos": 1183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1247, "end_pos": 1249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 975, "end_pos": 977, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "42032", "name": "", "equation": "N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5PK74-1", "A0A3Q1M3M3-1", "A0ABI0P1M0-1" ], "evidence": [ { "id": "42032", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42032" } ] }, { "id": "R-BTA-4722133", "name": "KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M3M3-1", "E1BPL5-1", "A0ABI0P1M0-1" ], "evidence": [ { "id": "R-BTA-4722133", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4722133" } ] }, { "id": "R-BTA-5661114", "name": "KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M3M3-1", "E1BPL5-1", "A0ABI0P1M0-1" ], "evidence": [ { "id": "R-BTA-5661114", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5661114" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1M3M3", "gene_name": "KDM2A", "activity": [ { "ec_number": "1.14.11.27", "activity": "N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "A0A3Q1M3M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3M3" } ] }, { "ec_number": "1.14.11.27", "activity": "", "evidence": [ { "id": "A0A3Q1M3M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3M3" } ] } ] }, { "uniprot_ac": "A0ABI0P1M0", "gene_name": "KDM2B", "activity": [ { "ec_number": "1.14.11.27", "activity": "N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "A0ABI0P1M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ] }, { "ec_number": "1.14.11.27", "activity": "", "evidence": [ { "id": "A0ABI0P1M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" } ] } ] }, { "uniprot_ac": "A5PK74", "gene_name": "RIOX1", "activity": [ { "ec_number": "1.14.11.27", "activity": "N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "A5PK74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PK74" } ] }, { "ec_number": "1.14.11.79", "activity": "L-histidyl-[protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-histidyl-[protein] + succinate + CO2.", "evidence": [ { "id": "A5PK74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PK74" } ] }, { "ec_number": "1.14.11.-", "activity": "", "evidence": [ { "id": "A5PK74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PK74" } ] } ] }, { "uniprot_ac": "E1BPL5", "gene_name": "KDM4A", "activity": [ { "ec_number": "1.14.11.69", "activity": "N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "E1BPL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPL5" } ] }, { "ec_number": "1.14.11.66", "activity": "N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2.", "evidence": [ { "id": "E1BPL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPL5" } ] }, { "ec_number": "1.14.11.69", "activity": "", "evidence": [ { "id": "E1BPL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPL5" } ] }, { "ec_number": "1.14.11.66", "activity": "", "evidence": [ { "id": "E1BPL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPL5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P1M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" }, { "id": "PS51058", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51058" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CXXC-type", "eco_id": "ECO_0000259", "start_pos": 579, "end_pos": 625, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P1M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1M0" }, { "id": "PS51184", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51184" } ], "ann_type": 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"BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 131, 422 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1108, "end_pos": 1110 }, { "start_pos": 1181, "end_pos": 1183 }, { "start_pos": 1247, "end_pos": 1249 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 573, "end_pos": 575 }, { "start_pos": 975, "end_pos": 977 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P2U4-1", "uniprot_ac": "A0ABI0P2U4", "uniprot_id": "A0ABI0P2U4_BOVIN", "mass": { "chemical_mass": 59913.0, "monoisotopic_mass": 59913.0 }, "refseq": { "ac": "NP_001192643", "name": "zinc finger protein 449", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192643" }, "gene_names": [ { "name": "ZNF449", "type": "recommended", "evidence": [ { "id": "A0ABI0P2U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2U4" } ] }, { "name": "ZNF449", "type": "synonym", "evidence": [ { "id": "NP_001192643", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192643" } ] } ], "protein_names": [ { "name": "Zinc finger protein 449", "type": "recommended", "evidence": [ { "id": "A0ABI0P2U4", "database": "UniProtKB", "url": 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"512036", "url": "https://www.ncbi.nlm.nih.gov/gene/512036", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512036", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512036", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MKQ9", "url": "https://www.orthodb.org/?gene=A0A3Q1MKQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226:SF377", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF377", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein 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"sequence": "MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYKEAAGPHEAFNKLWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQRELEIPEQQLDRQEMLLEELAPVGMAHIPPNIHLESPPLQVMGPAPEVPVAEAWIPQAGPQELSFSAAGEGQPFLDPGYPIPKLDVSFPLEHREEAWVKELQDSKEIKQLLDSKLGFEIGIENEEDTSEKQKKLENMYPFIVTLEGNALHGPILQKDYVQLENQWETPPEDLQGDLTKLVEHQNPSAGEKPESSNLEEPLNPRPHKKKSPGDKPHRCSQCGKCFARKSQLTGHQRIHSGEEPHKCPECGKRFLRSSDLYRHQRLHTGERPYECTVCKKRFTRRSHLIGHQRTHSEEETYKCLECGKSFCHGSSLKRHLKTHSGEKPHRCHNCGKSFSRLTALTLHQRTHTEERPFKCNYCGKSFRQRPSLVIHLRIHTGEKPYKCSHCSKSFRQRAGLIMHQVTHFRGLL", "length": 519, "header": "tr|A0ABI0P2U4-1|A0ABI0P2U4_BOVIN Isoform 1 of Zinc finger protein 449 OS=Bos taurus OX=9913 GN=ZNF449 PE=3 SV=1 CANONICAL=A0ABI0P2U4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MF16-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2U4/entry#A0A3Q1MF16-1", "sequence": { "sequence": "MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYKEAAGPHEAFNKLWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQRELEIPEQQLDRQEMLLEELAPVGMAHIPPNIHLESPPLQVMGPAPEVPVAEAWIPQAGPQELSFSAAGEGQPFLDPGYPIPKLDVSFPLEHREEAWVKELQDSKEIKQLLDSKLGFEIGIENEEDTSEKQKKLENMYPFIVTLEGNALHGPILQKDYVQLENQWETPPEDLQGDLTKLVEHQNPSAGEKPESSNLEEPLNPRPHKKKSPGDKPHRCSQCGKCFARKSQLTGHQRIHSGEEPHKCPECGKRFLRSSDLYRHQRLHTGERPYECTVCKKRFTRRSHLIGHQRTHSEEETYKCLECGKSFCHGSSLKRHLKTHSVKLLPRHQSLSSDGEEYKPGWTGRKAPAEAHSSALWKSSSSQASLCHFIQ", "length": 481, "header": "tr|A0A3Q1MF16-1|A0ABI0P2U4_BOVIN Computationally mapped isoform of Zinc finger protein 449 OS=Bos taurus OX=9913 GN=ZNF449 PE=3 SV=1 CANONICAL=A0ABI0P2U4-1" }, "locus": { "chromosome": "NKLS02002206.1", "start_pos": 61997, "end_pos": 47415, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066978.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066978.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072767.2", "url": 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"id": "ENSBTAT00000083169.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083169.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071499.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071499.2" } ] } }, { "isoform_ac": "A0ABI0P2U4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2U4/entry#A0ABI0P2U4-1", "sequence": { "sequence": "MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYKEAAGPHEAFNKLWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQRELEIPEQQLDRQEMLLEELAPVGMAHIPPNIHLESPPLQVMGPAPEVPVAEAWIPQAGPQELSFSAAGEGQPFLDPGYPIPKLDVSFPLEHREEAWVKELQDSKEIKQLLDSKLGFEIGIENEEDTSEKQKKLENMYPFIVTLEGNALHGPILQKDYVQLENQWETPPEDLQGDLTKLVEHQNPSAGEKPESSNLEEPLNPRPHKKKSPGDKPHRCSQCGKCFARKSQLTGHQRIHSGEEPHKCPECGKRFLRSSDLYRHQRLHTGERPYECTVCKKRFTRRSHLIGHQRTHSEEETYKCLECGKSFCHGSSLKRHLKTHSGEKPHRCHNCGKSFSRLTALTLHQRTHTEERPFKCNYCGKSFRQRPSLVIHLRIHTGEKPYKCSHCSKSFRQRAGLIMHQVTHFRGLL", "length": 519, "header": "tr|A0ABI0P2U4-1|A0ABI0P2U4_BOVIN Isoform 1 of Zinc finger protein 449 OS=Bos taurus OX=9913 GN=ZNF449 PE=3 SV=1 CANONICAL=A0ABI0P2U4-1" }, "locus": { "chromosome": "NKLS02002206.1", "start_pos": 55331, "end_pos": 47415, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148846.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148846.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107639.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107639.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:512036", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512036", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2U4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2U4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2U4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2U4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2U4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2U4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2U4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2U4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { 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"Protein Classification", "Other" ] }, { "id": "A0A3Q1MTA4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MTA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3R0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3R0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q6X7", "url": "https://www.uniprot.org/uniprotkb/F6Q6X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q6X7-1", "url": "https://www.uniprot.org/uniprotkb/F6Q6X7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AAAAGVGGCVGLAVGPRRASGPAGGRWRGPQQAAEAEVPGGRVAEGPGGSGGAALLQSLPAPPGLVCSRSGPPSPSSCSSRTSAGTGVAAQVYGLCSLPASVPCSVAPEKPVCRPQPPQVRRTFSLDTILSSYLLGQWPRDADGAFTCCTNDKATQTPLSWQELEGERAISCTHKRSASWGSTDHRKEITKLKQQLQRTKLSRSGKEKERGSPLQGDRAVRGARRASPPSFPTGSPVLRLSPCLHRSLEGLNQELEEVFVKDQGEEELLRILEIPDGHRAPAPSQSGSCDHPLLLLEPGNLASSPSIPLASPQPSGQTSREEHRGAAEELASVPSDKASSPGHPTFLEDGSPSPVLAFAASPRPNHSYVFKREPPEGCERVRVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVSLMKPLFPSMGFIFRNCPSSPGSPLPPASSRPPPRKDPEASKASSLPFEPWQRTPPSEEPVLFQSSLVV", "length": 487, "header": "tr|A0ABI0P3R0-1|A0ABI0P3R0_BOVIN Isoform 1 of Solute carrier family 35 member B1 OS=Bos taurus OX=9913 GN=FAM117A PE=4 SV=1 CANONICAL=A0ABI0P3R0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MTA4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R0/entry#A0A3Q1MTA4-1", "sequence": { "sequence": "MAAHLQSLLLPPPLGPITAMSSNGSPQKAVREYGGGCWGPPQRRSHAAPMRPLSPVGDVRLDLSPPPLPAVSGSPVGSSGRLMAASSSLVPDRLRLPLCFLGVFVCYFYYGILQEKITRGKYGEGAKQETFTFALTLVFIQCVVNAVFAKILIQFFDTARVDRTRSWLYAACSVSYLGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTLLKKKYPMAKYLCVLLIVAGVALFMYKPKKVVGIEEHTIGYGELLLLLSLTLDGLTGVSQDHMRAHYQTGSNHMMLNINLWSTLLLGAGILFTGELWEFLSFAERYPTIVYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPMQWVGTVLVFLGLGLDAKFGKGAKKTSH", "length": 404, "header": "tr|A0A3Q1MTA4-1|A0ABI0P3R0_BOVIN Computationally mapped isoform of Solute carrier family 35 member B1 OS=Bos taurus OX=9913 GN=FAM117A PE=4 SV=1 CANONICAL=A0ABI0P3R0-1" }, "locus": { "chromosome": "19", "start_pos": 36920553, "end_pos": 36907442, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080052.3", "url": "https://www.ensembl.org/id/ENSBTAT00000080052.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073499.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073499.2" } ] } }, { "isoform_ac": "A0ABI0P3R0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R0/entry#A0ABI0P3R0-1", "sequence": { "sequence": "AAAAGVGGCVGLAVGPRRASGPAGGRWRGPQQAAEAEVPGGRVAEGPGGSGGAALLQSLPAPPGLVCSRSGPPSPSSCSSRTSAGTGVAAQVYGLCSLPASVPCSVAPEKPVCRPQPPQVRRTFSLDTILSSYLLGQWPRDADGAFTCCTNDKATQTPLSWQELEGERAISCTHKRSASWGSTDHRKEITKLKQQLQRTKLSRSGKEKERGSPLQGDRAVRGARRASPPSFPTGSPVLRLSPCLHRSLEGLNQELEEVFVKDQGEEELLRILEIPDGHRAPAPSQSGSCDHPLLLLEPGNLASSPSIPLASPQPSGQTSREEHRGAAEELASVPSDKASSPGHPTFLEDGSPSPVLAFAASPRPNHSYVFKREPPEGCERVRVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVSLMKPLFPSMGFIFRNCPSSPGSPLPPASSRPPPRKDPEASKASSLPFEPWQRTPPSEEPVLFQSSLVV", "length": 487, "header": "tr|A0ABI0P3R0-1|A0ABI0P3R0_BOVIN Isoform 1 of Solute carrier family 35 member B1 OS=Bos taurus OX=9913 GN=FAM117A PE=4 SV=1 CANONICAL=A0ABI0P3R0-1" }, "locus": { "chromosome": "19", "start_pos": 36910696, "end_pos": 36869234, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151547.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151547.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106280.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106280.1" } ] } }, { "isoform_ac": "F6Q6X7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R0/entry#F6Q6X7-1", "sequence": { "sequence": "MAASSSLVPDRLRLPLCFLGVFVCYFYYGILQEKITRGKYGEGAKQETFTFALTLVFIQCVVNAVFAKILIQFFDTARVDRTRSWLYAACSVSYLGAMVSSNSALQFVNYPTQVKPQVMLLGVTLLKKKYPMAKYLCVLLIVAGVALFMYKPKKVVGIEEHTIGYGELLLLLSLTLDGLTGVSQDHMRAHYQTGSNHMMLNINLWSTLLLGAGILFTGELWEFLSFAERYPTIVYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPMQWVGTVLVFLGLGLDAKFGKGAKKTSH", "length": 316, "header": "tr|F6Q6X7-1|A0ABI0P3R0_BOVIN Computationally mapped isoform of Solute carrier family 35 member B1 OS=Bos taurus OX=9913 GN=FAM117A PE=4 SV=2 CANONICAL=A0ABI0P3R0-1" }, "locus": { "chromosome": "19", "start_pos": 36920553, "end_pos": 36914024, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009034.5", "url": "https://www.ensembl.org/id/ENSBTAT00000009034.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009034.4", "url": "https://www.ensembl.org/id/ENSBTAP00000009034.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3R0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3R0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 365, "end_pos": 367 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P1A4-1", "uniprot_ac": "A0ABI0P1A4", "uniprot_id": "A0ABI0P1A4_BOVIN", "mass": { "chemical_mass": 62909.0, "monoisotopic_mass": 62909.0 }, "refseq": {}, "gene_names": [ { "name": "FAM227B", "type": "recommended", "evidence": [ { "id": "A0ABI0P1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A4" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 227 member B", "type": "synonym", "evidence": [ { "id": "A0ABI0P1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1A4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM227B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A4", "locus": { "chromosome": "10", "start_pos": 60925175, "end_pos": 60722582, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000053150", "url": "https://www.ensembl.org/id/ENSBTAG00000053150" } ] } } ], "crossref": [ { "id": "ENSBTAG00000053150", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000053150", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR029417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MWX0", "url": "https://www.orthodb.org/?gene=A0A3Q1MWX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33560", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33560", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33560:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33560:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14922", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14922", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MWX0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MWX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVR5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVR5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9ST24", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9ST24-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYB8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYB8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZC9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZC9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1A4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1A4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6A2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6A2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGQLFPQLPHRTHGQKMQEPPKNIEEFLKLQNLDHWPKEIHLWDSDKLLYTMKKIKEDSSFTSIYTHLWGNVLRVDDAAMAMESRLAECSILLKNHASEIFEWNRIISRTISHGKLKQYKAFLKKYHKEKKIMLSDEMETKKDIEGCDFPGFRTNELTQLPRHLNAERIYLFILKAHNFDGKVFKIWRTHFLSEASLALLHDCFWWWFLHKFKPDRENQACLFDRISESYVSLFMSIPLSRKDTFFQVYPDCLAQAIYATFQEAFPESSNLFNDEFKEDLGNNIFLWLSGLPPQKGFWTHWKLKELSTTTIHGSKKMPSKSIKDMIARNQEQISASIDFNISKILENAKAYTTPAFKEESRPSKLPTKSHYISSGPEFNRVLFNFGGQSPLILYYLEMHEVAGISKAPRQVRIKLTEILKEPPPAPTYRDILKEAKRQFAKNRKEFRIENHVINEEIKLLRQRQEKVDKEFHRLQAKATKKPYEVKSDFENFLHQLRFEALTEREFLASLSSSSSSTEDPEEEECPEKPEVNCI", "length": 535, "header": "tr|A0ABI0P1A4-1|A0ABI0P1A4_BOVIN Isoform 1 of Family with sequence similarity 227 member B OS=Bos taurus OX=9913 GN=FAM227B PE=3 SV=1 CANONICAL=A0ABI0P1A4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MWX0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A4/entry#A0A3Q1MWX0-1", "sequence": { "sequence": "MAGQLFPQLPHRTHGQKMQEPPKNIEEFLKLQNLDHWPKEIHLWDSDKLLYTMKKIKEDSSFTSIYTHLWGNVLRVDDAAMAMESRLAECSILLKNHASEIFEWNRIISRTISHGKLKQYKAFLKKYHKEKKIMLSDEMETKKDIEGCDFPGFRTNELTQLPRHLNAERIYLFILKAHNFDGKVFKIWRTHFLSEASLALLHDCFWWWFLHKFKPDRENQACLFDRISESYVSLFMSIPLSRKDTFFQVYPDCLAQAIYATFQEAFPESSNLFNDEFKEDLGNNIFLWLSGLPPQKGFWTHWKLKELSTTTIHGSKKMPSKSIKDMIARNQEQISACSSVHMILPAKILEWVVMPSSKGSS", "length": 361, "header": "tr|A0A3Q1MWX0-1|A0ABI0P1A4_BOVIN Computationally mapped isoform of Family with sequence similarity 227 member B OS=Bos taurus OX=9913 GN=FAM227B PE=3 SV=2 CANONICAL=A0ABI0P1A4-1" }, "locus": { "chromosome": "10", "start_pos": 60774557, "end_pos": 60723892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067566.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067566.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060107.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060107.2" } ] } }, { "isoform_ac": "A0AAA9RVR5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A4/entry#A0AAA9RVR5-1", "sequence": { "sequence": "MAGQLFPQLPHRTHGQKMQEPPKNIEEFLKLQNLDHWPKEIHLWDSDKLLYTMKKIKEDSSFTSIYTHLWGNVLRVDDAAMAMESRLAECSILLKNHASEIFEWNRIISRTISHGKLKQYKAFLKKYHKEKKIMLSDEMETKKDIEGCDFPGFRTNELTQLPRHLNAERIYLFILKAHNFDGKVFKIWRTHFLSEASLALLHDCFWWWFLHKFKPDRENQACLFDRISESYVSLFMSIPLSRKDTFFQVYPDCLAQAIYATFQEAFPESSNLFNDEFKEDLGNNIFLWLSGLPPQKGFWTHWKLKELSTTTIHGSKKMPSKSIKDMIARNQEQISAYGWRRKWQPTPVLLPGESHGGRSLVGYRPWGRKESETTEPLSLHYRWVLY", "length": 386, "header": "tr|A0AAA9RVR5-1|A0ABI0P1A4_BOVIN Computationally mapped isoform of Family with sequence similarity 227 member B OS=Bos taurus OX=9913 GN=FAM227B PE=3 SV=1 CANONICAL=A0ABI0P1A4-1" }, "locus": { "chromosome": "10", "start_pos": 60763907, "end_pos": 60723892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096457.2", "url": "https://www.ensembl.org/id/ENSBTAT00000096457.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077467.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077467.1" } ] } }, { "isoform_ac": "A0AAA9ST24-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A4/entry#A0AAA9ST24-1", "sequence": { "sequence": "MAGQLFPQLPHRTHGQKMQEPPKNIEEFLKLQNLDHWPKEIHLWDSDKLLYTMKKIKEDSSFTSIYTHLWGNVLRVDDAAMAMESRLAECSILLKNHASEIFEWNRIISRTISHGKLKQYKAFLKKYHKEKKIMLSDEMETKKDIEGCDFPGFRTNELTQLPRHLNAERIYLFILKAHNFDGKVFKIWRTHFLSEASLALLHDCFWWWFLHKFKPDRENQACLFDRISESYVSLFMSIPLSRKDTFFQVYPDCLAQAIYATFQEAFPESSNLFNDEFKEDLGNNIFLWLSGLPPQKGFWTHWKLKELSTTTIHGSKKMPSKSIKDMIARNQEQISASIDFNISKILENAKAYTTPAFKEESRPSKLPTKEAKRQFAKNRKEFRIENHVINEEIKLLRQRQEKVDKEFHRLQAKATKKPYEVKSDFENFLHQLRFEALTEREFLASLSSSSSSTEDPEEEECPEKPEVNCI", "length": 470, "header": "tr|A0AAA9ST24-1|A0ABI0P1A4_BOVIN Computationally mapped isoform of Family with sequence similarity 227 member B OS=Bos taurus OX=9913 GN=FAM227B PE=3 SV=1 CANONICAL=A0ABI0P1A4-1" }, "locus": { "chromosome": "10", "start_pos": 60924615, "end_pos": 60723892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110844.2", "url": "https://www.ensembl.org/id/ENSBTAT00000110844.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086181.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086181.1" } ] } }, { "isoform_ac": "A0AAA9SYB8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A4/entry#A0AAA9SYB8-1", "sequence": { "sequence": "MAGQLSCHRTHGQKMQEPPKNIEEFLKLQNLDHWPKEIHLWDSDKLLYTMKKIKEDSSFTSIYTHLWGNVLRVDDAAMAMESRLAECSILLKNHASEIFEWNRIISRTISHGKLKQYKAFLKKYHKEKKIMLSDEMETKKDIEGCDFPGFRTNELTQLPRHLNAERIYLFILKAHNFDGKVFKIWRTHFLSEASLALLHDCFWWWFLHKFKPDRENQACLFDRISESYVSLFMSIPLSRKDTFFQVYPDCLAQAIYATFQEAFPESSNLFNDEFKEDLGNNIFLWLSGLPPQKGFWTHWKLKELSTTTIHGSKKMPSKSIKDMIARNQEQISASIDFNISKILENAKAYTTPAFKEESRPSKLPTKSHYISSGPEFNRVLFNFGGQSPLILYYLEMHEVAGISKAPRQVRIKLTEILKEPPPAPTYRDILKEAKRQFAKNRKEFRILQAKATKKPYEVKSDFENFLHQLRFEALTEREFLASLSSSSSSTEDPEEEECPEKPEVNCI", "length": 507, "header": "tr|A0AAA9SYB8-1|A0ABI0P1A4_BOVIN Computationally mapped isoform of Family with sequence similarity 227 member B OS=Bos taurus OX=9913 GN=FAM227B PE=3 SV=1 CANONICAL=A0ABI0P1A4-1" }, "locus": { "chromosome": "10", "start_pos": 60924615, "end_pos": 60723892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122231.2", "url": "https://www.ensembl.org/id/ENSBTAT00000122231.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090360.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090360.1" } ] } }, { "isoform_ac": "A0ABI0NZC9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A4/entry#A0ABI0NZC9-1", "sequence": { "sequence": "MAGQLFPQLPHRTHGQKMQEPPKNIEEFLKLQNLDHWPKEIHLWDSDKLLYTMKKIKEDSSFTSIYTHLWGNVLRVDDAAMAMESRLAECSILLKNHASEIFEWNRIISRTISHGKLKQYKAFLKKYHKEKKIMLSDEMETKKDIEGCDFPGFRTNELTQLPRHLNAERIYLFILKAHNFDGKVFKIWRTHFLSEASLALLHDCFWWWFLHKFKPDRENQACLFDRISESYVSLFMSIPLSRKDTFFQVYPDCLAQAIYATFQEAFPESSNLFNDEFKEDLGNNIFLWLSGLPPQKGFWTHWKLKELSTTTIHGSKKMPSKSIKDMIARNQEQISACRSDGTVLKIRLCGFRLGHSFSLILSNSLLCGKRTAMWQMELWQGLCGEEVVFQTHNQ", "length": 394, "header": "tr|A0ABI0NZC9-1|A0ABI0P1A4_BOVIN Computationally mapped isoform of Family with sequence similarity 227 member B OS=Bos taurus OX=9913 GN=FAM227B PE=3 SV=1 CANONICAL=A0ABI0P1A4-1" }, "locus": { "chromosome": "10", "start_pos": 60786746, "end_pos": 60723892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143617.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143617.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104128.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104128.1" } ] } }, { "isoform_ac": "A0ABI0P1A4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A4/entry#A0ABI0P1A4-1", "sequence": { "sequence": "MAGQLFPQLPHRTHGQKMQEPPKNIEEFLKLQNLDHWPKEIHLWDSDKLLYTMKKIKEDSSFTSIYTHLWGNVLRVDDAAMAMESRLAECSILLKNHASEIFEWNRIISRTISHGKLKQYKAFLKKYHKEKKIMLSDEMETKKDIEGCDFPGFRTNELTQLPRHLNAERIYLFILKAHNFDGKVFKIWRTHFLSEASLALLHDCFWWWFLHKFKPDRENQACLFDRISESYVSLFMSIPLSRKDTFFQVYPDCLAQAIYATFQEAFPESSNLFNDEFKEDLGNNIFLWLSGLPPQKGFWTHWKLKELSTTTIHGSKKMPSKSIKDMIARNQEQISASIDFNISKILENAKAYTTPAFKEESRPSKLPTKSHYISSGPEFNRVLFNFGGQSPLILYYLEMHEVAGISKAPRQVRIKLTEILKEPPPAPTYRDILKEAKRQFAKNRKEFRIENHVINEEIKLLRQRQEKVDKEFHRLQAKATKKPYEVKSDFENFLHQLRFEALTEREFLASLSSSSSSTEDPEEEECPEKPEVNCI", "length": 535, "header": "tr|A0ABI0P1A4-1|A0ABI0P1A4_BOVIN Isoform 1 of Family with sequence similarity 227 member B OS=Bos taurus OX=9913 GN=FAM227B PE=3 SV=1 CANONICAL=A0ABI0P1A4-1" }, "locus": { "chromosome": "10", "start_pos": 60924615, "end_pos": 60723892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144215.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144215.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104258.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104258.1" } ] } }, { "isoform_ac": "A0ABI0P6A2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A4/entry#A0ABI0P6A2-1", "sequence": { "sequence": "MAGQLSCHRTHGQKMQEPPKNIEEFLKLQNLDHWPKEIHLWDSDKLLYTMKKIKEDSSFTSIYTHLWGNVLRVDDAAMAMESRLAECSILLKNHASEIFEWNRIISRTISHGKLKQYKAFLKKYHKEKKIMLSDEMETKKDIEGCDFPGFRTNELTQLPRHLNAERIYLFILKAHNFDGKVFKIWRTHFLSEASLALLHDCFWWWFLHKFKVYPDCLAQAIYATFQEAFPESSNLFNDEFKEDLGNNIFLWLSGLPPQKGFWTHWKLKELSTTTIHGSKKMPSKSIKDMIARNQEQISASIDFNISKILENAKAYTTPAFKEESRPSKLPTKSHYISSGPEFNRVLFNFGGQSPLILYYLEMHEVAGISKAPRQVRIKLTEILKEPPPAPTYRDILKEAKRQFAKNRKEFRIENHVINEEIKLLRQRQEKVDKEFHRLQAKATKKPYEVKSDFENFLHQLRFEALTEREFLASLSSSSSSTEDPEEEECPEKPEVNCI", "length": 498, "header": "tr|A0ABI0P6A2-1|A0ABI0P6A2_BOVIN Computationally mapped isoform of Family with sequence similarity 227 member B OS=Bos taurus OX=9913 GN=FAM227B PE=3 SV=1 CANONICAL=A0ABI0P1A4-1" }, "locus": { "chromosome": "10", "start_pos": 60924615, "end_pos": 60723892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152558.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152558.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106840.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106840.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 341, "end_pos": 343 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P4X8-1", "uniprot_ac": "A0ABI0P4X8", "uniprot_id": "A0ABI0P4X8_BOVIN", "mass": { "chemical_mass": 94311.0, "monoisotopic_mass": 94311.0 }, "refseq": { "ac": "XP_059736030", "name": "protein CFAP20DC isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059736030" }, "gene_names": [ { "name": "CFAP20DC", "type": "recommended", "evidence": [ { "id": "A0ABI0P4X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8" } ] }, { "name": "CFAP20DC", "type": "synonym", "evidence": [ { "id": "XP_059736030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059736030" } ] } ], "protein_names": [ { "name": "CFAP20 domain containing", "type": "synonym", "evidence": [ { "id": "A0ABI0P4X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8/entry#names_and_taxonomy" } ] }, { "name": "protein CFAP20DC isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059736030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059736030" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4X8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CFAP20DC", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000020373", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020373", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "534800", "url": "https://www.ncbi.nlm.nih.gov/gene/534800", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534800", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534800", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR12458", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12458", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059736030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059736030", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1NLW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NLW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NN96", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NN96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NN96-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NN96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKJ9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLD4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLD4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NP06", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NP06-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXX5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXX5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0G1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0G1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0G1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4X8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4X8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P7A9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P7A9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7A9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFKNEYQGGAFVEIFSAQGKNPGAKWKILGSPSVIWKEFDKEVKSFVFVLEGSSQTNKIQLPKENKQILGLIQRFLVLQIYIPLGQDFSTELLITDLRNIKRRLYLSTVHKELSSTPLHAKIPLFMIKRKIWCNLCIDLVAFTNEIFKGAVFQSLDGITVSANCKLRKIFTLKYKPQDTADKDAGQDAPFPIDEPIDIIPRSCQLTTDVPQVTQLLNMTKLRQTEIKFGGHPLNSTESDQFINRGTVSMRNSKHQDVCHIAFGSKVLGPPPLSGRRNNMRLSNETVRSVGSKSNRLHQQSTVEKCVNGAEMSALLLSESEAQGDKENIGQIKQTVPVLASLHIMHPHPPQEPSADKNNNRRRLRLKSTSRERTETPSGNSSDNNRNDEHKAATVLTAMSQQRAKTMNPSSPVPQSPDQADEWVFPENGDHIPYLASTPQSLLVDEDSCHTSCLWLEASKESEQDQQTEETQIVPKGVFTFSSRPRSAPHGKTQSMSPEGCPFTLDLKEDTSVTRSDTETEEDFYGADSSEEDNHSVQGSPGPTTSPPGLTQLSLESMLGKAAKCASKEYLKNAYAEGRTSENQNSLAKQIDIKDFETSFVPKPSLSPPGRHESSPKIPDLVIKPKDLPTHQVSASINKTFLKEISEEKLKPIAELSSQGLPAYKRAPKSLWMMTAAMKLKHSCSLEEKEYDWRNYQPSEISESELQMLASLRRQQNEELEDTGAPYGLSASQVDNCNVSISTSSDDTTTWNSCLPPPVNQGRHYQKEMNPPSPSNPRDWLNMLSPPIVPPSQESAERHQDSSGSLSVQGEEELSVEEDEEVLTLLYDPCLNCYFDPQTGKYYELV", "length": 845, "header": "tr|A0ABI0P4X8-1|A0ABI0P4X8_BOVIN Isoform 1 of CFAP20 domain containing OS=Bos taurus OX=9913 GN=CFAP20DC PE=4 SV=1 CANONICAL=A0ABI0P4X8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NLW7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8/entry#A0A3Q1NLW7-1", "sequence": { "sequence": "MSTRITDLRNIKRRLYLSTVHKELSSTPLHAKIPLFMIKRKIWCNLCIDLVAFTNEIFKGAVFQSLDGITVSANCKLRKIFTLKYKPQDTADKDGMFKLLSRFFSSPF", "length": 108, "header": "tr|A0A3Q1NLW7-1|A0ABI0P4X8_BOVIN Computationally mapped isoform of CFAP20 domain containing OS=Bos taurus OX=9913 GN=CFAP20DC PE=4 SV=3 CANONICAL=A0ABI0P4X8-1" }, "locus": { "chromosome": "22", "start_pos": 42477816, "end_pos": 42346787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082685.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082685.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073469.3", "url": "https://www.ensembl.org/id/ENSBTAP00000073469.3" } ] } }, { "isoform_ac": "A0A3Q1NN96-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8/entry#A0A3Q1NN96-1", "sequence": { "sequence": "MFKNEYQGGAFVEIFSAQGKNPGAKWKILGSPSVIWKEFDKEVKSFVFVLEGSSQTNKIQLPKENKQILGLIQRFLVLQIYIPLGQDFSTELLITDLRNIKRRLYLSTVHKELSSTPLHAKIPLFMIKRKIWCNLCIDLVAFTNEIFKGAVFQSLDGITVSANCKLRKIFTLKYKPQDTADKDAGQDAPFPIDEPIDIIPRSCQLTTDVPQVTQLLNMTKLRQTEIKFGGHPLNSTESDQFINRGTVSMRNSKHQDVCHIAFGSKVLGPPPLSGRRNNMRLSNETVRSVGSKSNRLHQQSTVEKCVNGAEMSALLLSESEAQGDKENIGQIKQTVPVLASLHIMHPHPPQEPSADKNNNRRRLRLKSTSRERTETPSGNSSDNNRNDEHKAATVLTAMSQQRAKTMNPSSPVPQSPDQADEWVFPENGDHIPYLASTPQSLLVDEDSCHTSCLWLEASKESEQDQQTEETQIVPKGVFTFSSRPRSAPHGKTQSMSPEGCPFTLDLKEDTSVTRSDTETEEDFYGADSSEEDNHSVQGSPGPTTSPPGLTQLSLESMLGKAAKCASKEYLKNAYAEGRTSENQNSLAKQIDIKDFETSFVPKPSLSPPGRHESSPKIPDLVIKPKDLPTHQVSASINKTFLKEISEEKLKPIAELSEYDWRNYQPSEISESELQMLASLRRQQNEELEDTGAPYGLSASQVDNCNVSISTSSDDTTTWNSCLPPPVNQGRHYQKEMNPPSPSNPRLPLDISERGE", "length": 755, "header": "tr|A0A3Q1NN96-1|A0ABI0P4X8_BOVIN Computationally mapped isoform of CFAP20 domain containing OS=Bos taurus OX=9913 GN=CFAP20DC PE=4 SV=3 CANONICAL=A0ABI0P4X8-1" }, "locus": { "chromosome": "22", "start_pos": 42568997, "end_pos": 42346777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068730.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068730.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074193.3", "url": "https://www.ensembl.org/id/ENSBTAP00000074193.3" } ] } }, { "isoform_ac": "A0ABI0NKJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8/entry#A0ABI0NKJ9-1", "sequence": { "sequence": "MFKNEYQGGAFVEIFSAQGKNPGAKWKILGSPSVIWKEFDKEVKSFVFVLEGSSQTNKIQLPKENKQILGLIQRFLVLQIYIPLGQDFSTELLITDLRNIKRRLYLSTVHKELSSTPLHAKIPLFMIKRKIWCNLCIDLVAFTNEIFKGAVFQSLDGITVSANCKLRKIFTLKYKPQDTADKDAGQDAPFPIDEPIDIIPRSCQLTTDVPQVTQLLNMTKLRQTEIKFGGHPLNSTESDQFINRGTVSMRNSKHQDVCHIAFGSKVLGPPPLSGRRNNMRLSNETVRSVGSKSNRLHQQSTVEKCVNGAEMSALLLSESEAQGDKENIGQIKQTVPVLASLHIMHPHPPQEPSADKNNNRRRLRLKSTSRERTETPSGNSSDNNRNDEHKAATVLTAMSQQRAKTMNPSSPVPQSPDQADEWVFPENGDHIPYLASTPQSLLVDEDSCHTSCLWLEASKESEQDQQTEETQIVPKGVFTFSSRPRSAPHGKTQSMSPEGCPFTLDLKEDTSVTRSDTETEEDFYGADSSEEEYDWRNYQPSEISESELQMLASLRRQQNEELEDTGAPYGLSASQVDNCNVSISTSSDDTTTWNSCLPPPVNQGRHYQKEMNPPSPSNPRDWLNMLSPPIVPPSQESAERHQDSSGSLSVQGEEELSVEEDEEVLTLLYDPCLNCYFDPQTGKYYELV", "length": 688, "header": "tr|A0ABI0NKJ9-1|A0ABI0P4X8_BOVIN Computationally mapped isoform of CFAP20 domain containing OS=Bos taurus OX=9913 GN=CFAP20DC PE=4 SV=1 CANONICAL=A0ABI0P4X8-1" }, "locus": { "chromosome": "22", "start_pos": 42616268, "end_pos": 42346777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137329.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137329.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105262.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105262.1" } ] } }, { "isoform_ac": "A0ABI0NLD4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8/entry#A0ABI0NLD4-1", "sequence": { "sequence": "MFKNEYQGGAFVEIFSAQGKNPGAKWKILGSPSVIWKEFDKEVKSFVFVLEGSSQTNKIQLPKENKQILGLIQRFLVLQIYIPLGQDFSTELLITDLRNIKRRLYLSTVHKELSSTPLHAKIPLFMIKRKIWCNLCIDLVAFTNEIFKGAVFQSLDGITVSANCKLRKIFTLKYKPQDTADKDAGQDAPFPIDEPIDIIPRSCQLTTDVPQVTQLLNMTKLRQTEIKFGGHPLNSTESDQFINRGTVSMRNSKHQDVCHIAFGSKVLGPPPLSGRRNNMRLSNETVRSVGSKSNRLHQQSTVEKCVNGAEMSALLLSESEAQGDKENIGQIKQTVPVLASLHIMHPHPPQEPSADKNNNRRRLRLKSTSRERTETPSGNSSDNNRNDEHKAATVLTAMSQQRAKTMNPSSPVPQSPDQADEWVFPENGDHIPYLASTPQSLLVDEDSCHTSCLWLEASKESEQDQQTEETQIVPKGVFTFSSRPRSAPHGKTQSMSPEGCPFTLDLKEDTSVTRSDTETEEDFYGADSSEEDNHSVQGSPGPTTSPPGLTQLSLESMLGKAAKCASKEYLKNAYAEGRTSENQNSLAKQIDIKDFETSFVPKPSLSPPGRHESSPKIPDLVIKPKDLPTHQVSASINKTFLKEISEEKLKPIAELSEYDWRNYQPSEISESELQMLASLRRQQNEELEDTGAPYGLSASQVDNCNVSISTSSDDTTTWNSCLPPPVNQGRHYQKEMNPPSPSNPRDWLNMLSPPIVPPSQESAERHQDSSGSLSVQEPSYLQHSCLPALTSRPHKDGPPGQMVKRS", "length": 806, "header": "tr|A0ABI0NLD4-1|A0ABI0P4X8_BOVIN Computationally mapped isoform of CFAP20 domain containing OS=Bos taurus OX=9913 GN=CFAP20DC PE=4 SV=1 CANONICAL=A0ABI0P4X8-1" }, "locus": { "chromosome": "22", "start_pos": 42616170, "end_pos": 42346777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142989.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142989.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105843.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105843.1" } ] } }, { "isoform_ac": "A0ABI0NP06-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8/entry#A0ABI0NP06-1", "sequence": { "sequence": "MFKNEYQGGAFVEIFSAQGKNPGAKWKILGSPSVIWKEFDKEVKSFVFVLEGSSQTNKIQLPKENKQILGLIQRFLVLQIYIPLGQDFSTELLITDLRNIKRRLYLSTVHKELSSTPLHAKIPLFMIKRKIWCNLCIDLVAFTNEIFKGAVFQSLDGITVSANCKLRKIFTLKYKPQDTADKDAGQDAPFPIDEPIDIIPRSCQLTTDVPQVTQLLNMTKLRQTEIKFGGHPLNSTESDQFINRGTVSMRNSKHQDVCHIAFGSKVLGPPPLSGRRNNMRLSNETVRSVGSKSNRLHQQSTVEKCVNGAEMSALLLSESEAQGDKENIGQIKQTVPVLGNSSDNNRNDEHKAATVLTAMSQQRAKTMNPSSPVPQSPDQADEWVFPENGDHIPYLASTPQSLLVDEDSCHTSCLWLEASKESEQDQQTEETQIVPKGVFTFSSRPRSAPHGKTQSMSPEGCPFTLDLKEDTSVTRSDTETEEDFYGADSSEEDNHSVQGSPGPTTSPPGLTQLSLESMLGKAAKCASKEYLKNAYAEGRTSENQNSLAKQIDIKDFETSFVPKPSLSPPGRHESSPKIPDLVIKPKDLPTHQVSASINKTFLKEISEEKLKPIAELSEYDWRNYQPSEISESELQMLASLRRQQNEELEDTGAPYGLSASQVDNCNVSISTSSDDTTTWNSCLPPPVNQGRHYQKEMNPPSPSNPRDWLNMLSPPIVPPSQESAERHQDSSGSLSVQGEEELSVEEDEEVLTLLYDPCLNCYFDPQTGKYYELV", "length": 774, "header": "tr|A0ABI0NP06-1|A0ABI0P4X8_BOVIN Computationally mapped isoform of CFAP20 domain containing OS=Bos taurus OX=9913 GN=CFAP20DC PE=4 SV=1 CANONICAL=A0ABI0P4X8-1" }, "locus": { "chromosome": "22", "start_pos": 42616268, "end_pos": 42346777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142440.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142440.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107552.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107552.1" } ] } }, { "isoform_ac": "A0ABI0NXX5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8/entry#A0ABI0NXX5-1", "sequence": { "sequence": "MFKNEYQGGAFVEIFSAQGKNPGAKWKILGSPSVIWKEFDKEVKSFVFVLEGSSQTNKIQLPKENKQILGLIQRFLVLQIYIPLGQDFSTELLITDLRNIKRRLYLSTVHKELSSTPLHAKIPLFMIKRKIWCNLCIDLVAFTNEIFKGAVFQSLDGITVSANCKLRKIFTLKYKPQDTADKDAGQDAPFPIDEPIDIIPRSCQLTTDVPQVTQLLNMTKLRQTEIKFGGHPLNSTESDQFINRGTVSMRNSKHQDVCHIAFGSKVLGPPPLSGRRNNMRLSNETVRSVGSKSNRLHQQSTVEKCVNGAEMSALLLSESEAQGDKENIGQIKQTVPVLASLHIMHPHPPQEPSADKNNNRRRLRLKSTSRERTETPSGNSSDNNRNDEHKAATVLTAMSQQRAKTMNPSSPVPQSPDQADEWVFPENGDHIPYLASTPQSLLVDEDSCHTSCLWLEASKESEQDQQTEETQIVPKGVFTFSSRPRSAPHGKTQSMSPEGCPFTLDLKEDTSVTRSDTETEEDFYGADSSEEDNHSVQGSPGPTTSPPGLTQLSLESMLGKAAKCASKEYLKNAYAEGRTSENQNSLAKQIDIKDFETSFVPKPSLSPPGRHESSPKIPDLVIKPKDLPTHQVSASINKTFLKEISEEKLKPIAELSEYDWRNYQPSEISESELQMLASLRRQQNEELEDTGAPYGLSASQVDNCNVSISTSSDDTTTWNSCLPPGLVKYAEPTNCSSQSRVRRAASGFFWKLECSR", "length": 756, "header": "tr|A0ABI0NXX5-1|A0ABI0P4X8_BOVIN Computationally mapped isoform of CFAP20 domain containing OS=Bos taurus OX=9913 GN=CFAP20DC PE=4 SV=1 CANONICAL=A0ABI0P4X8-1" }, "locus": { "chromosome": "22", "start_pos": 42616159, "end_pos": 42346777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149717.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149717.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104992.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104992.1" } ] } }, { "isoform_ac": "A0ABI0P0G1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8/entry#A0ABI0P0G1-1", "sequence": { "sequence": "MFKNEYQGGAFVEIFSAQGKNPGAKWKILGSPSVIWKEFDKEVKSFVFVLEGSSQTNKIQLPKENKQILGLIQRFLVLQIYIPLGQDFSTELLITDLRNIKRRLYLSTVHKELSSTPLHAKIPLFMIKRKIWCNLCIDLVAFTNEIFKGAVFQSLDGITVSANCKLRKIFTLKYKPQDTADKDAGQDAPFPIDEPIDIIPRSCQLTTDVPQVTQLLNMTKLRQTEIKFGGHPLNSTESDQFINRGTVSMRNSKHQDVCHIAFGSKVLGPPPLSGRRNNMRLSNETVRSVGSKSNRLHQQSTVEKCVNGAEMSALLLSESEAQGDKENIGQIKQTVPVLASLHIMHPHPPQEPSADKNNNRRRLRLKSTSRERTETPSGNSSDNNRNDEHKAATVLTAMSQQRAKTMNPSSPVPQSPDQADEWVFPENGDHIPYLASTPQSLLVDEDSCHTSCLWLEASKESEQDQQTEETQIVPKGVFTFSSRPRSAPHGKTQSMSPEGCPFTLDLKEDTSVTRSDTETEEDFYGADSSEEDNHSVQGSPGPTTSPPGLTQLSLESMLGKAAKCASKEYLKNAYAEGRTSENQNSLAKQIDIKDFETSFVPKPSLSPPGRHESSPKIPDLVIKPKDLPTHQVSASINKTFLKEISEEKLKPIAELSEYDWRNYQPSEISESELQMLASLRRQQNEELEDTGAPYGLSASQVDNCNVSISTSSDDTTTWNSCLPPPVNQGRHYQKEMNPPSPSNPRDWLNMLSPPIVPPSQESAERHQDSSGSLSVQGEEELSVEEDEEVLTLLYDPCLNCYFDPQTGKYYELV", "length": 813, "header": "tr|A0ABI0P0G1-1|A0ABI0P0G1_BOVIN Computationally mapped isoform of CFAP20 domain containing OS=Bos taurus OX=9913 GN=CFAP20DC PE=4 SV=1 CANONICAL=A0ABI0P4X8-1" }, "locus": { "chromosome": "22", "start_pos": 42616268, "end_pos": 42346777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141421.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141421.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106407.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106407.1" } ] } }, { "isoform_ac": "A0ABI0P4X8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8/entry#A0ABI0P4X8-1", "sequence": { "sequence": "MFKNEYQGGAFVEIFSAQGKNPGAKWKILGSPSVIWKEFDKEVKSFVFVLEGSSQTNKIQLPKENKQILGLIQRFLVLQIYIPLGQDFSTELLITDLRNIKRRLYLSTVHKELSSTPLHAKIPLFMIKRKIWCNLCIDLVAFTNEIFKGAVFQSLDGITVSANCKLRKIFTLKYKPQDTADKDAGQDAPFPIDEPIDIIPRSCQLTTDVPQVTQLLNMTKLRQTEIKFGGHPLNSTESDQFINRGTVSMRNSKHQDVCHIAFGSKVLGPPPLSGRRNNMRLSNETVRSVGSKSNRLHQQSTVEKCVNGAEMSALLLSESEAQGDKENIGQIKQTVPVLASLHIMHPHPPQEPSADKNNNRRRLRLKSTSRERTETPSGNSSDNNRNDEHKAATVLTAMSQQRAKTMNPSSPVPQSPDQADEWVFPENGDHIPYLASTPQSLLVDEDSCHTSCLWLEASKESEQDQQTEETQIVPKGVFTFSSRPRSAPHGKTQSMSPEGCPFTLDLKEDTSVTRSDTETEEDFYGADSSEEDNHSVQGSPGPTTSPPGLTQLSLESMLGKAAKCASKEYLKNAYAEGRTSENQNSLAKQIDIKDFETSFVPKPSLSPPGRHESSPKIPDLVIKPKDLPTHQVSASINKTFLKEISEEKLKPIAELSSQGLPAYKRAPKSLWMMTAAMKLKHSCSLEEKEYDWRNYQPSEISESELQMLASLRRQQNEELEDTGAPYGLSASQVDNCNVSISTSSDDTTTWNSCLPPPVNQGRHYQKEMNPPSPSNPRDWLNMLSPPIVPPSQESAERHQDSSGSLSVQGEEELSVEEDEEVLTLLYDPCLNCYFDPQTGKYYELV", "length": 845, "header": "tr|A0ABI0P4X8-1|A0ABI0P4X8_BOVIN Isoform 1 of CFAP20 domain containing OS=Bos taurus OX=9913 GN=CFAP20DC PE=4 SV=1 CANONICAL=A0ABI0P4X8-1" }, "locus": { "chromosome": "22", "start_pos": 42616268, "end_pos": 42346777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143674.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143674.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106410.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106410.1" } ] } }, { "isoform_ac": "A0ABI0P7A9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8/entry#A0ABI0P7A9-1", "sequence": { "sequence": "MSTRITDLRNIKRRLYLSTVHKELSSTPLHAKIPLFMIKRKIWCNLCIDLVAFTNEIFKGAVFQSLDGITVSANCKLRKIFTLKYKPQDTADKDAGQDAPFPIDEPIDIIPRSCQLTTDVPQVTQLLNMTKLRQTEIKFGGHPLNSTESDQFINRGTVSMRNSKHQDVCHIAFGSKVLGPPPLSGRRNNMRLSNETVRSVGSKSNRLHQQSTVEKCVNGAEMSALLLSESEAQGDKENIGQIKQTVPVLASLHIMHPHPPQEPSADKNNNRRRLRLKSTSRERTETPSGNSSDNNRNDEHKAATVLTAMSQQRAKTMNPSSPVPQSPDQADEWVFPENGDHIPYLASTPQSLLVDEDSCHTSCLWLEASKESEQDQQTEETQIVPKGVFTFSSRPRSAPHGKTQSMSPEGCPFTLDLKEDTSVTRSDTETEEDFYGADSSEEDNHSVQGSPGPTTSPPGLTQLSLESMLGKAAKCASKEYLKNAYAEGRTSENQNSLAKQIDIKDFETSFVPKPSLSPPGRHESSPKIPDLVIKPKDLPTHQVSASINKTFLKEISEEKLKPIAELSEYDWRNYQPSEISESELQMLASLRRQQNEELEDTGAPYGLSASQVDNCNVSISTSSDDTTTWNSCLPPPVNQGRHYQKEMNPPSPSNPRDWLNMLSPPIVPPSQESAERHQDSSGSLSVQGEEELSVEEDEEVLTLLYDPCLNCYFDPQTGKYYELV", "length": 724, "header": "tr|A0ABI0P7A9-1|A0ABI0P7A9_BOVIN Computationally mapped isoform of CFAP20 domain containing OS=Bos taurus OX=9913 GN=CFAP20DC PE=4 SV=1 CANONICAL=A0ABI0P4X8-1" }, "locus": { "chromosome": "22", "start_pos": 42616268, "end_pos": 42346787, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152440.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152440.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107259.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107259.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 543, "start_aa": "Thr", "end_pos": 543, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr543", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:534800", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534800", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 737, "end_pos": 739, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P4X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4X8" }, { "id": "PF05018", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05018" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CFA20", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 181, "start_aa": "Met", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 543 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 217, "end_pos": 219 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 379, "end_pos": 381 }, { "start_pos": 533, "end_pos": 535 }, { "start_pos": 637, "end_pos": 639 }, { "start_pos": 737, "end_pos": 739 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, 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"categories": [ "Protein Classification" ] }, { "id": "IPR040077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051369", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051369", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3S5ZPD5", "url": "https://www.orthodb.org/?gene=A0A3S5ZPD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11954", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11954", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11954:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11954:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43917", 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3S5ZPD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z9U9", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z9U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z9U9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z9U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NV77", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NV77-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NX87", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NX87-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3R2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3R2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGEGVAGLGYQELRTSLCWVTGGTRPLPFLSWVLPAVPAPAMGLELYLDLLSQPCRAVYIFAKKNSIPFELRTVDLLKGQNHSDDFVQVNPLRKVPALKDGDFTLAESVAILLYLARKYEAPDHWYPQDLQARARVDEYLSWQHTALRTSCTRTMWQKMMFPIFLGQRVPPETLANTLAELDRCLQLLEDKFLKDQDFLAGPHMSVADLVAITELMHRVNVTVRSGLAMVVNGSAEPSAQLLVSSIGVVGTAEENRGHSARFFEFLTKELDLAEDRIMIRFFPLERWQIGKKGTVMTFL", "length": 300, "header": "tr|A0ABI0P3R2-1|A0ABI0P3R2_BOVIN Isoform 1 of glutathione transferase OS=Bos taurus OX=9913 GN=GSTT2 PE=1 SV=1 CANONICAL=A0ABI0P3R2-1" }, "isoforms": [ { "isoform_ac": "A0A3S5ZPD5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2/entry#A0A3S5ZPD5-1", "sequence": { "sequence": 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"MPFVELDTSLPAGRVPAGLEKRLCAATAAILSKPEDRVNVTVRSGLAMVVNGSAEPSAQLLVSSIGVVGTAEENRGHSARFFEFLTKELDLAEDRGSCDTRARYGLLDLSVSICEMGRLPFNDSWGHCMGWHCTVPALAPGRAGCCYPDRTKATYHLPSGFCI", "length": 163, "header": "tr|A0AAF6Z9U9-1|A0ABI0P3R2_BOVIN Computationally mapped isoform of glutathione transferase OS=Bos taurus OX=9913 GN=GSTT2 PE=1 SV=1 CANONICAL=A0ABI0P3R2-1" }, "locus": { "chromosome": "17", "start_pos": 71336164, "end_pos": 71335106, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029458.4", "url": "https://www.ensembl.org/id/ENSBTAT00000029458.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029458.3", "url": "https://www.ensembl.org/id/ENSBTAP00000029458.3" } ] } }, { "isoform_ac": "A0ABI0NV77-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2/entry#A0ABI0NV77-1", "sequence": { "sequence": "MPFVELDTSLPAGRVPAGLEKRLCAATAAILSKPEDRVNVTVRSGLAMVVNGSAEPSAQLLVSSIGVVGTAEENRGHSARFFEFLTKELDLAEDRSRGAARRVRGEAGGAEARAAWWAGQASARREPGLSGTQIGESASCGKIQAHPRPLVNNESGPFHCPE", "length": 162, "header": "tr|A0ABI0NV77-1|A0ABI0P3R2_BOVIN Computationally mapped isoform of glutathione transferase OS=Bos taurus OX=9913 GN=GSTT2 PE=1 SV=1 CANONICAL=A0ABI0P3R2-1" }, "locus": { "chromosome": "17", "start_pos": 71341567, "end_pos": 71335106, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144688.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144688.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105283.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105283.1" } ] } }, { "isoform_ac": "A0ABI0NX87-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2/entry#A0ABI0NX87-1", "sequence": { "sequence": "MPFVELDTSLPAGRVPAGLEKRLCAATAAILSKPEDRVNVTVRSGLAMVVNGSAEPSAQLLVSSIGVVGTAEENRGHSARFFEFLTKELDLAEDRSLLLGPPSPSFFNFRTSFVIKLRGESCIQGCKLPLKL", "length": 132, "header": "tr|A0ABI0NX87-1|A0ABI0P3R2_BOVIN Computationally mapped isoform of glutathione transferase OS=Bos taurus OX=9913 GN=GSTT2 PE=1 SV=1 CANONICAL=A0ABI0P3R2-1" }, "locus": { "chromosome": "17", "start_pos": 71344580, "end_pos": 71335106, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137408.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137408.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104601.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104601.1" } ] } }, { "isoform_ac": "A0ABI0P3R2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2/entry#A0ABI0P3R2-1", "sequence": { "sequence": "MGGEGVAGLGYQELRTSLCWVTGGTRPLPFLSWVLPAVPAPAMGLELYLDLLSQPCRAVYIFAKKNSIPFELRTVDLLKGQNHSDDFVQVNPLRKVPALKDGDFTLAESVAILLYLARKYEAPDHWYPQDLQARARVDEYLSWQHTALRTSCTRTMWQKMMFPIFLGQRVPPETLANTLAELDRCLQLLEDKFLKDQDFLAGPHMSVADLVAITELMHRVNVTVRSGLAMVVNGSAEPSAQLLVSSIGVVGTAEENRGHSARFFEFLTKELDLAEDRIMIRFFPLERWQIGKKGTVMTFL", "length": 300, "header": "tr|A0ABI0P3R2-1|A0ABI0P3R2_BOVIN Isoform 1 of glutathione transferase OS=Bos taurus OX=9913 GN=GSTT2 PE=1 SV=1 CANONICAL=A0ABI0P3R2-1" }, "locus": { "chromosome": "17", "start_pos": 71337580, "end_pos": 71328580, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139966.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139966.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105508.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105508.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 223, "start_aa": "Thr", "end_pos": 223, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr223", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3R2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2" } ], "pmid": "" }, { "name": "D-dopachrome decarboxylase activity", "id": "GO:0033981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3R2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": 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"crossref": [ { "id": "ENSBTAG00000047520", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047520", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11266", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11266", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11266:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11266:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04117", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04117", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NKG3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKG3-1", "url": 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GN=MPV17L PE=3 SV=1 CANONICAL=A0ABI0P2E1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NKG3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E1/entry#A0ABI0NKG3-1", "sequence": { "sequence": "MVSWWQALTRAAGRYPWPANVLLYAGFFSGGDALQQVLRGGPADWQHTRHVATVAVAFHANLNYVWLNLLERALPGRAPRTILAKVLCDQALGGPVYVSTFYAEWSDVLAFCTADQLQPHSHSLANSLHWTLWFSVGHLPLFFSTGR", "length": 147, "header": "tr|A0ABI0NKG3-1|A0ABI0P2E1_BOVIN Computationally mapped isoform of MPV17 mitochondrial inner membrane protein like OS=Bos taurus OX=9913 GN=MPV17L PE=3 SV=1 CANONICAL=A0ABI0P2E1-1" }, "locus": { "chromosome": "25", "start_pos": 13821484, "end_pos": 13816701, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104987.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104987.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105207.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105207.1" } ] } }, { "isoform_ac": "A0ABI0P2E1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E1/entry#A0ABI0P2E1-1", "sequence": { "sequence": "MVSWWQALTRAAGRYPWPANVLLYAGFFSGGDALQQVLRGGPADWQHTRHVATVAVAFHANLNYVWLNLLERALPGRAPRTILAKVLCDQALGGPVYVSTFYAGMSILQGKDDIFLDMRQKFWNTYKSGLMYWPFVQLINFSLIPIRWRTAYTGLCGFLWATFLCFSQQEGDGTFKSAFTFRRIKGTNEVEKPSEK", "length": 196, "header": "tr|A0ABI0P2E1-1|A0ABI0P2E1_BOVIN Isoform 1 of MPV17 mitochondrial inner membrane protein like OS=Bos taurus OX=9913 GN=MPV17L PE=3 SV=1 CANONICAL=A0ABI0P2E1-1" }, "locus": { "chromosome": "25", "start_pos": 13821560, "end_pos": 13816701, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149346.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149346.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104721.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104721.1" } ] } }, { "isoform_ac": "G5E6R0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E1/entry#G5E6R0-1", "sequence": { "sequence": "MVSWWQALTRAAGRYPWPANVLLYAGFFSGGDALQQVLRGGPADWQHTRHVATVAVAFHANLNYVWLNLLERALPGRAPRTILAKVLCDQALGGPVYVSTFYAGMSILQGKDDIFLDMRQKFWNTYKLINFSLIPIRWRTAYTGLCGFLWATFLCFSQQEGDGTFKSAFTFRRIKGTNEVEKPSEK", "length": 186, "header": "tr|G5E6R0-1|A0ABI0P2E1_BOVIN Computationally mapped isoform of MPV17 mitochondrial inner membrane protein like OS=Bos taurus OX=9913 GN=MPV17L PE=3 SV=2 CANONICAL=A0ABI0P2E1-1" }, "locus": { "chromosome": "25", "start_pos": 13821560, "end_pos": 13816701, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063390.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063390.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056473.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056473.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2E1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2E1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2E1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "id": "GO:1901029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901029", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2E1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P1B8-1", "uniprot_ac": "A0ABI0P1B8", "uniprot_id": "A0ABI0P1B8_BOVIN", "mass": { "chemical_mass": 84351.0, "monoisotopic_mass": 84351.0 }, "refseq": {}, "gene_names": [ { "name": "KRTAP16-1", "type": "recommended", "evidence": [ { "id": "A0ABI0P1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B8" } ] } ], "protein_names": [ { "name": "Keratin associated protein 16-1", "type": "synonym", "evidence": [ { "id": "A0ABI0P1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S0J5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0J5#function" }, { "database": "UniProtKB", "id": "ARBA00003327", "url": "https://www.uniprot.org/uniprotkb/ARBA00003327#function" }, { "database": "UniProtKB", "id": "A0AAA9TPF6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPF6#function" }, { "database": "UniProtKB", "id": "A0AAA9U1P3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1P3#function" }, { "database": "UniProtKB", "id": "A0ABI0P1B8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1B8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KRTAP16-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B8", "locus": {} } ], "crossref": [ { "id": "IPR002494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23262", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23262", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23262:SF55", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23262:SF55", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S0J5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0J5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0J5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPF6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPF6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1P3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1P3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1B8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1B8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGLKTARARVGGIKVRALESCPSQAATSQHWQGSRGNSTMSGNCCSRKCPSVPAISLCSTEVSYRGPVCLPSSCRSQTWQLVTCQDSCGSSSCDPQCCQPSCSASSCAQPVSCEATICEPACPVVSCAQPVSCEATICEPVCPVIGCAQPVCYETTICEPACPVSSCAQPVYCEATICEPACPVISCAQPVCYKATICEPSCPVSSCANPVSCEATICEPACPVSSCAQPVCCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSSCAQPVSCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSSCAQPVCCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSSCAQPVSCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSRCTQPVSCEATICEPSCSVSSCAQPVCCEVPPGQRVFCIPTSCQPILCKPSCCQPVVCEPSCYQPVSSGVRCCPSICSVANSCQSACCDSSPCEPSCSEPSICQSATRVSLVCEPICVRPVCCVSSPCEPPCVSSTCQEPSCCVSSICQPICSEPSPCLPSVCVPRPCQPTCYVVKRSRSISCEPPSCRPLSCRPGSSASAVCQPTCSRTFYIPSSCKQPCTTSISYRPICRPICSGPITYRQPYLTSISYRPACYRPYCSILRRPACITSVPYRSVCSRLPYADSCKRDCKKSTSSQPDCADSTPCKTEVSEASPCQPTEAKPTSPTTHEAAVSQPAATKPTNC", "length": 811, "header": "tr|A0ABI0P1B8-1|A0ABI0P1B8_BOVIN Isoform 1 of Keratin associated protein 16-1 OS=Bos taurus OX=9913 GN=KRTAP16-1 PE=4 SV=1 CANONICAL=A0ABI0P1B8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S0J5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B8/entry#A0AAA9S0J5-1", "sequence": { "sequence": "MWGLKTARARVGGIKVRALESCPSQAATSQHWQGSRGNSTMSGNCCSRKCPSVPAISLCSTEVSYRGPVCLPSSCRSQTWQLVTCQDSCGSSSCDPQCCQPSCSASSCAQPVSCEATICEPACPVVSCAQPVSCEATICEPVCPVIGCAQPVCYETTICEPACPVSSCAQPVYCEATICEPACPVISCAQPVCYKATICEPSCPVSSCANPVSCEATICEPACPVSSCAQPVCCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSSCAQPVSCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSSCAQPVSCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSRCTQPVSCEATICEPSCSVSSCAQPVCCEVPPGQRVFCIPTSCQPILCKPSCCQPVVCEPSCYQPVSSGVRCCPSICSVANSCQSACCDSSPCEPSCSEPSICQSATRVSLVCEPICVRPVCCVSSPCEPPCVSSTCQEPSCCVSSICQPICSEPSPCLPSVCVPRPCQPTCYVVKRSRSISCEPPSCRPLSCRPGSSASAVCQPTCSRTFYIPSSCKQPCTTSISYRPICRPICSGPITYRQPYLTSISYRPACYRPYCSILRRPACITSVPYRSVCSRLPYADSCKRDCKKSTSSQPDCADSTPCKTEVSEASPCQPTEAKPTSPTTHEAAVSQPAATKPTNC", "length": 751, "header": "tr|A0AAA9S0J5-1|A0ABI0P1B8_BOVIN Computationally mapped isoform of Keratin associated protein 16-1 OS=Bos taurus OX=9913 GN=KRTAP16-1 PE=4 SV=2 CANONICAL=A0ABI0P1B8-1" }, "locus": { "chromosome": "19", "start_pos": 41520240, "end_pos": 41517628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096542.2", "url": "https://www.ensembl.org/id/ENSBTAT00000096542.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075583.2", "url": "https://www.ensembl.org/id/ENSBTAP00000075583.2" } ] } }, { "isoform_ac": "A0AAA9TPF6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B8/entry#A0AAA9TPF6-1", "sequence": { "sequence": "MWGLKTARARVGGIKVRALESCPSQAATSQHWQGSRGNSTMSGNCCSRKCPSVPAISLCSTEVSYRGPVCLPSSCRSQTWQLVTCQDSCGSSSCDPQCCQPSCSASSCAQPVSCEATICEPACPVVSCAQPVSCEATICEPVCPVIGCAQPVCYETTICEPACPVSSCAQPVYCEATICEPSCPVSSCANPVSCEATICEPACPVSSCAQPVCCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSSCAQPVCCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSRCTQPVSCEATICEPSCSVSSCAQPVCCEVPPGQRVFCIPTSCQPILCKPSCCQPVVCEPSCYQPVSSGVRCCPSICSVANSCQSACCDSSPCEPSCSEPSICQSATRVSLVCEPICVRPVCCVSSPCEPPCVSSTCQEPSCCVSSICQPICSEPSPCLPSVCVPRPCQPTCYVVKRSRSISCEPPSCRPLSCRPGSSASAVCQPTCSRTFYIPSSCKQPCTTSISYRPICRPICSGPITYRQPYLTSISYRPACYRPYCSILRRPACITSVPYRSVCSRLPYADSCKRDCKKSTSSQPDCADSTPCKTEVSEASPCQPTEAKPTSPTTHEAAVSQPAATKPTNC", "length": 671, "header": "tr|A0AAA9TPF6-1|A0ABI0P1B8_BOVIN Computationally mapped isoform of Keratin associated protein 16-1 OS=Bos taurus OX=9913 GN=KRTAP16-1 PE=4 SV=1 CANONICAL=A0ABI0P1B8-1" }, "locus": { "chromosome": "19", "start_pos": 41520240, "end_pos": 41517628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119605.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119605.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099152.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099152.1" } ] } }, { "isoform_ac": "A0AAA9U1P3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B8/entry#A0AAA9U1P3-1", "sequence": { "sequence": "MWGLKTARARVGGIKVRALESCPSQAATSQHWQGSRGNSTMSGNCCSRKCPSVPAISLCSTEVSYRGPVCLPSSCRSQTWQLVTCQDSCGSSSCDPQCCQPSCSASSCAQPVSCEATICEPACPVVSCAQPVSCEATICEPVCPVIGCAQPVCYETTICEPACPVSSCAQPVYCEATICEPACPVISCAQPVCYKATICEPSCPVSSCANPVSCEATICEPACPVSSCAQPVCCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSSCAQPVCCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSSCAQPVSCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSSCAQPVCCEVPPGQRVFCIPTSCQPILCKPSCCQPVVCEPSCYQPVSSGVRCCPSICSVANSCQSACCDSSPCEPSCSEPSICQSATRVSLVCEPICVRPVCCVSSPCEPPCVSSTCQEPSCCVSSICQPICSEPSPCLPSVCVPRPCQPTCYVVKRSRSISCEPPSCRPLSCRPGSSASAVCQPTCSRTFYIPSSCKQPCTTSISYRPICRPICSGPITYRQPYLTSISYRPACYRPYCSILRRPACITSVPYRSVCSRLPYADSCKRDCKKSTSSQPDCADSTPCKTEVSEASPCQPTEAKPTSPTTHEAAVSQPAATKPTNC", "length": 731, "header": "tr|A0AAA9U1P3-1|A0ABI0P1B8_BOVIN Computationally mapped isoform of Keratin associated protein 16-1 OS=Bos taurus OX=9913 GN=KRTAP16-1 PE=4 SV=1 CANONICAL=A0ABI0P1B8-1" }, "locus": { "chromosome": "19", "start_pos": 41520240, "end_pos": 41517628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126687.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126687.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103162.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103162.1" } ] } }, { "isoform_ac": "A0ABI0P1B8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B8/entry#A0ABI0P1B8-1", "sequence": { "sequence": "MWGLKTARARVGGIKVRALESCPSQAATSQHWQGSRGNSTMSGNCCSRKCPSVPAISLCSTEVSYRGPVCLPSSCRSQTWQLVTCQDSCGSSSCDPQCCQPSCSASSCAQPVSCEATICEPACPVVSCAQPVSCEATICEPVCPVIGCAQPVCYETTICEPACPVSSCAQPVYCEATICEPACPVISCAQPVCYKATICEPSCPVSSCANPVSCEATICEPACPVSSCAQPVCCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSSCAQPVSCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSSCAQPVCCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSSCAQPVSCEATICEPSCSVSSCAQPVYYKATICEPACPVSSCAKPVSCEATICEPACPVSRCTQPVSCEATICEPSCSVSSCAQPVCCEVPPGQRVFCIPTSCQPILCKPSCCQPVVCEPSCYQPVSSGVRCCPSICSVANSCQSACCDSSPCEPSCSEPSICQSATRVSLVCEPICVRPVCCVSSPCEPPCVSSTCQEPSCCVSSICQPICSEPSPCLPSVCVPRPCQPTCYVVKRSRSISCEPPSCRPLSCRPGSSASAVCQPTCSRTFYIPSSCKQPCTTSISYRPICRPICSGPITYRQPYLTSISYRPACYRPYCSILRRPACITSVPYRSVCSRLPYADSCKRDCKKSTSSQPDCADSTPCKTEVSEASPCQPTEAKPTSPTTHEAAVSQPAATKPTNC", "length": 811, "header": "tr|A0ABI0P1B8-1|A0ABI0P1B8_BOVIN Isoform 1 of Keratin associated protein 16-1 OS=Bos taurus OX=9913 GN=KRTAP16-1 PE=4 SV=1 CANONICAL=A0ABI0P1B8-1" }, "locus": { "chromosome": "19", "start_pos": 41520240, "end_pos": 41517628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151198.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151198.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107689.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107689.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1B8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B8" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1B8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 38, "end_pos": 40 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P4A7-1", "uniprot_ac": "A0ABI0P4A7", "uniprot_id": "A0ABI0P4A7_BOVIN", "mass": { "chemical_mass": 20330.0, "monoisotopic_mass": 20330.0 }, "refseq": {}, "gene_names": [ { "name": "HOATZ", "type": "recommended", "evidence": [ { "id": "A0ABI0P4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4A7" } ] } ], "protein_names": [ { "name": "Cilia- and flagella-associated protein HOATZ", "type": "recommended", "evidence": [ { "id": "A0ABI0P4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4A7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4A7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4A7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HOATZ", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4A7", "locus": { "chromosome": "15", "start_pos": 21853035, "end_pos": 21818528, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000034338", "url": "https://www.ensembl.org/id/ENSBTAG00000034338" } ] } } ], "crossref": [ { "id": "767960", "url": "https://www.ncbi.nlm.nih.gov/gene/767960", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47231:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47231:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S5K8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5K8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5K8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZH79", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZH79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZH79-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZH79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7AI35", "url": "https://www.uniprot.org/uniprotkb/A0AAF7AI35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7AI35-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF7AI35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS53", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS53-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4A7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4A7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4A7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METRPSSSLSSPEESCEAFPQGLLVFTGSSDRDANLAKQFWIGASMYPHNESQLVLSRGSSQRLPVARPSRSSAPEKTYFQPFFLEESKSRDVTAETLKIQESEEKKKYLQKAKKRDEIIQLLRKQREERILVRLIVRRWEMVELKDRQPQEMEGKLQFHSHLLIEHANTHLYL", "length": 174, "header": "tr|A0ABI0P4A7-1|A0ABI0P4A7_BOVIN Isoform 1 of Cilia- and flagella-associated protein HOATZ OS=Bos taurus OX=9913 GN=HOATZ PE=3 SV=1 CANONICAL=A0ABI0P4A7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S5K8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4A7/entry#A0AAA9S5K8-1", "sequence": { "sequence": "METRPSSSLSSPEESCEAFPQGLLVFTGSSDRDANLAKQFWIGASMYPHNESQLVLSRGSSQRLPVARPSRSSAPEKTYFQPFFLEESKSRDVTAETLKIQESEEKKKYLQKAKKRDEIIQLLRKQREERILVRLIKELISLPHKPKGKVHKAKIGMQADLFQSCGHC", "length": 168, "header": "tr|A0AAA9S5K8-1|A0ABI0P4A7_BOVIN Computationally mapped isoform of Cilia- and flagella-associated protein HOATZ OS=Bos taurus OX=9913 GN=HOATZ PE=3 SV=1 CANONICAL=A0ABI0P4A7-1" }, "locus": { "chromosome": "15", "start_pos": 21850159, "end_pos": 21818727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127255.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127255.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078558.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078558.1" } ] } }, { "isoform_ac": "A0AAF6ZH79-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4A7/entry#A0AAF6ZH79-1", "sequence": { "sequence": "METRPSSSLSSPEESCEAFPQGLLVFTGSSDRDANLAKQFWIGASMYPHNESQLVLSRGSSQRLPVARPSRSSAPESRDVTAETLKIQESEEKKKYLQKAKKRDEIIQLLRKQREERILKELISLPHKPKGKVHKAKKVISESDKEDQEEVKALD", "length": 155, "header": "tr|A0AAF6ZH79-1|A0ABI0P4A7_BOVIN Computationally mapped isoform of Cilia- and flagella-associated protein HOATZ OS=Bos taurus OX=9913 GN=HOATZ PE=3 SV=1 CANONICAL=A0ABI0P4A7-1" }, "locus": { "chromosome": "15", "start_pos": 21852895, "end_pos": 21818727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000048644.4", "url": "https://www.ensembl.org/id/ENSBTAT00000048644.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000045643.2", "url": "https://www.ensembl.org/id/ENSBTAP00000045643.2" } ] } }, { "isoform_ac": "A0AAF7AI35-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4A7/entry#A0AAF7AI35-1", "sequence": { "sequence": "METRPSSSLSSPEESCEAFPQGLLVFTGSSDRDANLAKQFWIGASMYPHNESQLVLSRGSSQRLPVARPSRSSAPEKTYFQPFFLEESKSRDVTAETLKIQESEEKKKYLQKAKKRDEIIQLLRKQREERILESDFRVRQRRPGRSQSLGLI", "length": 152, "header": "tr|A0AAF7AI35-1|A0ABI0P4A7_BOVIN Computationally mapped isoform of Cilia- and flagella-associated protein HOATZ OS=Bos taurus OX=9913 GN=HOATZ PE=3 SV=1 CANONICAL=A0ABI0P4A7-1" }, "locus": { "chromosome": "15", "start_pos": 21852900, "end_pos": 21818727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081696.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081696.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069629.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069629.2" } ] } }, { "isoform_ac": "A0ABI0NS53-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4A7/entry#A0ABI0NS53-1", "sequence": { "sequence": "METRPSSSLSSPEESCEAFPQGLLVFTGSSDRDANLAKQFWIGASMYPHNESQLVLSRGSSQRLPVARPSRSSAPEKTYFQPFFLEESKSRDVTAETLKIQESEEKKKYLQKAKKRDEIIQLLRKQREERILVRLIKELISLPHKPKGKVHKAKKVISESDKEDQEEVKALD", "length": 172, "header": "tr|A0ABI0NS53-1|A0ABI0P4A7_BOVIN Computationally mapped isoform of Cilia- and flagella-associated protein HOATZ OS=Bos taurus OX=9913 GN=HOATZ PE=3 SV=1 CANONICAL=A0ABI0P4A7-1" }, "locus": { "chromosome": "15", "start_pos": 21852895, "end_pos": 21818727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142352.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142352.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106757.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106757.1" } ] } }, { "isoform_ac": "A0ABI0P4A7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4A7/entry#A0ABI0P4A7-1", "sequence": { "sequence": "METRPSSSLSSPEESCEAFPQGLLVFTGSSDRDANLAKQFWIGASMYPHNESQLVLSRGSSQRLPVARPSRSSAPEKTYFQPFFLEESKSRDVTAETLKIQESEEKKKYLQKAKKRDEIIQLLRKQREERILVRLIVRRWEMVELKDRQPQEMEGKLQFHSHLLIEHANTHLYL", "length": 174, "header": "tr|A0ABI0P4A7-1|A0ABI0P4A7_BOVIN Isoform 1 of Cilia- and flagella-associated protein HOATZ OS=Bos taurus OX=9913 GN=HOATZ PE=3 SV=1 CANONICAL=A0ABI0P4A7-1" }, "locus": { "chromosome": "15", "start_pos": 21848382, "end_pos": 21818727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149672.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149672.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106374.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106374.1" } ] } } ], "glycosylation": 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"start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P0W2-1", "uniprot_ac": "A0ABI0P0W2", "uniprot_id": "A0ABI0P0W2_BOVIN", "mass": { "chemical_mass": 90644.0, "monoisotopic_mass": 90644.0 }, "refseq": {}, "gene_names": [ { "name": "ADAM9", "type": "recommended", "evidence": [ { "id": "A0ABI0P0W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0W2" } ] } ], "protein_names": [ { "name": "ADAM metallopeptidase domain 9", "type": "synonym", "evidence": [ { "id": "A0ABI0P0W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0W2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0W2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0W2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ADAM9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0W2", "locus": { "chromosome": "27", "start_pos": 34242502, "end_pos": 34221774, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017455", "url": "https://www.ensembl.org/id/ENSBTAG00000017455" } ] } } ], "crossref": [ { "id": "ENSBTAG00000017455", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017455", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M4H2", "url": "https://www.orthodb.org/?gene=A0A3Q1M4H2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905:SF136", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905:SF136", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1M4H2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M4H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4H2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAV0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAV0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ15", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ15-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXJ6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0W2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0W2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0W2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P535", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P535", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P535-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P535-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSGVGSPSETLRVRWLLLVGLLSPALGGARSGFQQTSHLSFYEIITPWKLTRERREAPRPFSEQVSYVIQAEGKEHIIHLERNKDLLPKDFVVYTYNKEGALISDHPSIQNHCHYRGYVEGTYDSSIALSDCFGLRGLLHIENVSYGIEPLQNSSHFEHIFYRMDDVHQEPLKCGVSNKVMEEETTKDEEEEHPSITQLLRRKRDILPQTRYVELFIVVEKEKYDNMGKNQTAVREEMISLANYLDSMYIMLNIRIVLVGLEIWTNENLISMAGGAGDVLSNFVQWREKFLITRRRHDSAQLILKRGFGGTAGMAFVGTVCSRSHAGGINVFGQIPVEKFASIVAHELGHNLGMSHDDGRGCHCPVKSCIMNSGASGSKNFSSCSADDFEKLTLNKGGNCLLNIPKGDEAYSAPSCGNKLVDPGEECDCGSPKECELDPCCEGKTCKLKSFAECAYGACCQDCRFRPGGTLCRGKTNECDVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPKECFLDVNSKGDRFGNCGFSGHEYKKCAIGNALCGKLQCENVQQLPVFGVVPAIIQTPGKGTKCWGVDFQLGSDVPDPGMVNEGTSCDVGKICRNFACVNVSVLNYDCDIQQKCHGHGVCNSNKNCHCDNGWAPPNCETKGYGGSVDSGPTYNENNAALRDGLLVFFFLILPLTVLAVFVFIKRDQLRKSCCRRKRSQTNESGGKNQAKDSRQPASVPRPVSSVIPPRNVPVQTNRFPVPTYGARQPQQYPSRPPPPQPKESFQGNLVPARPAPPPPPPLYSSLT", "length": 821, "header": "tr|A0ABI0P0W2-1|A0ABI0P0W2_BOVIN Isoform 1 of ADAM metallopeptidase domain 9 OS=Bos taurus OX=9913 GN=ADAM9 PE=4 SV=1 CANONICAL=A0ABI0P0W2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M4H2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0W2/entry#A0A3Q1M4H2-1", "sequence": { "sequence": "MGSGVGSPSETLRVRWLLLVGLLSPALGGARSGFQQTSHLSFYEIITPWKLTRERREAPRPFSEQNHCHYRGYVEGTYDSSIALSDCFGLRGLLHIENVSYGIEPLQNSSHFEHIFYRMDDVHQEPLKCGVSNKVMEEETTKDEEEEHPSITQLLRRKRDILPQTRYVELFIVVEKEKYDNMGKNQTAVREEMISLANYLDSMYIMLNIRIVLVGLEIWTNENLISMAGGAGDVLSNFVQWREKFLITRRRHDSAQLILKRGFGGTAGMAFVGTVCSRSHAGGINVFGQIPVEKFASIVAHELGHNLGMSHDDGRGCHCPVKSCIMNSGASGSKNFSSCSADDFEKLTLNKGGNCLLNIPKGDEAYSAPSCGNKLVDPGEECDCGSPKECELDPCCEGKTCKLKSFAECAYGACCQDCRFRPGGTLCRGKTNECDVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPKECFLDVNSKGDRFGNCGFSGHEYKKCAIGNALCGKLQCENVQQLPVFGVVPAIIQTPGKGTKCWGVDFQLGSDVPDPGMVNEGTSCDVGKICRNFACVNVSVLNYDCDIQQKCHGHGVCNSNKNCHCDNGWAPPNCETKGYGGSVDSGPTYNENNAALRDGLLVFFFLILPLTVLAVFVFIKRDQLRKSCCRRKRSQTNESGGKNQAKDSRQPASVPRPVSSVIPPRNVPVQTNRFPVPTYGARQPQQYPSRPPPPQPKESFQGNLVPARPAPPPPPPLYSSLT", "length": 775, "header": "tr|A0A3Q1M4H2-1|A0ABI0P0W2_BOVIN Computationally mapped isoform of ADAM metallopeptidase domain 9 OS=Bos taurus OX=9913 GN=ADAM9 PE=4 SV=3 CANONICAL=A0ABI0P0W2-1" }, "locus": { "chromosome": "27", "start_pos": 34241119, "end_pos": 34152503, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079444.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079444.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063154.3", "url": "https://www.ensembl.org/id/ENSBTAP00000063154.3" } ] } }, { "isoform_ac": "A0AAA9SAV0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0W2/entry#A0AAA9SAV0-1", "sequence": { "sequence": "MGSGVGSPSETLRVRWLLLVGLLSPALGGARSGFQQTSHLSFYEIITPWKLTRERREAPRPFSEQVSYVIQAEGKEHIIHLERNKDLLPKDFVVYTYNKEGALISDHPSIQVIYFPLDHIEFKTIIIL", "length": 128, "header": "tr|A0AAA9SAV0-1|A0ABI0P0W2_BOVIN Computationally mapped isoform of ADAM metallopeptidase domain 9 OS=Bos taurus OX=9913 GN=ADAM9 PE=4 SV=1 CANONICAL=A0ABI0P0W2-1" }, "locus": { "chromosome": "27", "start_pos": 34174016, "end_pos": 34152503, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127550.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127550.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083226.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083226.1" } ] } }, { "isoform_ac": "A0ABI0NQ15-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0W2/entry#A0ABI0NQ15-1", "sequence": { "sequence": "MGSGVGSPSETLRVRWLLLVGLLSPALGGARSGFQQTSHLSFYEIITPWKLTRERREAPRPFSEQVSYVIQAEGKEHIIHLERNKDLLPKDFVVYTYNKEGALISDHPSIQNHCHYRGYVEGTYDSSIALSDCFGLRGLLHIENVSYGIEPLQNSSHFEHIFYRMDDVHQEPLKCGVSNKVMEEETTKDEEEEHPSITQLLRRKRDILPQTRYVELFIVVEKEKYDNMGKNQTAVREEMISLANYLDSMYIMLNIRIVLVGLEIWTNENLISMAGGAGDVLSNFVQWREKFLITRRRHDSAQLILKRGFGGTAGMAFVGTVCSRSHAGGINVFGQIPVEKFASIVAHELGHNLGMSHDDGRGCHCPVKSCIMNSGASGSKNFSSCSADDFEKLTLNKGGNCLLNIPKGDEAYSAPSCGNKLVDPGEECDCGSPKECELDPCCEGKTCKLKSFAECAYGACCQDCRFRPGGTLCRGKTNECDVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPKECFLDVNSKGDRFGNCGFSGHEYKKCAIGNALCGKLQCENVQQLPVFGVVPAIIQTPGKGTKCWGVDFQLGSDVPDPGMVNEGTSCDVGKICRNFACVNVSVLNYDCDIQQKCHGHGRDQLRKSCCRRKRSQTNESGGKNQAKDSRQPASVPRPVSSVIPPRNVPVQTNRFPVPTYGARQPQQYPSRPPPPQPKESFQGNLVPARPAPPPPPPLYSSLT", "length": 756, "header": "tr|A0ABI0NQ15-1|A0ABI0P0W2_BOVIN Computationally mapped isoform of ADAM metallopeptidase domain 9 OS=Bos taurus OX=9913 GN=ADAM9 PE=4 SV=1 CANONICAL=A0ABI0P0W2-1" }, "locus": { "chromosome": "27", "start_pos": 34241119, "end_pos": 34152503, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146430.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146430.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104173.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104173.1" } ] } }, { "isoform_ac": "A0ABI0NXJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0W2/entry#A0ABI0NXJ6-1", "sequence": { "sequence": "MTGEWGSPYSQLAAPGEPSGWAAPADVSSGSAVALCEWLRDTQCSSSRFPSSRAAWPHRSFQQTSHLSFYEIITPWKLTRERREAPRPFSEQVSYVIQAEGKEHIIHLERNKDLLPKDFVVYTYNKEGALISDHPSIQNHCHYRGYVEGTYDSSIALSDCFGLRGLLHIENVSYGIEPLQNSSHFEHIFYRMDDVHQEPLKCGVSNKVMEEETTKDEEEEHPSITQLLRRKRDILPQTRYVELFIVVEKEKYDNMGKNQTAVREEMISLANYLDSMYIMLNIRIVLVGLEIWTNENLISMAGGAGDVLSNFVQWREKFLITRRRHDSAQLILKRGFGGTAGMAFVGTVCSRSHAGGINVFGQIPVEKFASIVAHELGHNLGMSHDDGRGCHCPVKSCIMNSGASGSKNFSSCSADDFEKLTLNKGGNCLLNIPKGDEAYSAPSCGNKLVDPGEECDCGSPKECELDPCCEGKTCKLKSFAECAYGACCQDCRFRPGGTLCRGKTNECDVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPKECFLDVNSKGDRFGNCGFSGHEYKKCAIGNALCGKLQCENVQQLPVFGVVPAIIQTPGKGTKCWGVDFQLGSDVPDPGMVNEGTSCDVGKICRNFACVNVSVLNYDCDIQQKCHGHGVCNSNKNCHCDNGWAPPNCETKGYGGSVDSGPTYNENNAALRDGLLVFFFLILPLTVLAVFVFIKRDQLRKSCCRRKRSQTNESGGKNQAKDSRQPASVPRPVSSVIPPRNVPVQTNRFPVPTYGARQPQQYPSRPPPPQPKESFQGNLVPARPAPPPPPPLYSSLT", "length": 848, "header": "tr|A0ABI0NXJ6-1|A0ABI0P0W2_BOVIN Computationally mapped isoform of ADAM metallopeptidase domain 9 OS=Bos taurus OX=9913 GN=ADAM9 PE=4 SV=1 CANONICAL=A0ABI0P0W2-1" }, "locus": { "chromosome": "27", "start_pos": 34241119, "end_pos": 34151692, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140986.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140986.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105941.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105941.1" } ] } }, { "isoform_ac": "A0ABI0P0W2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0W2/entry#A0ABI0P0W2-1", "sequence": { "sequence": "MGSGVGSPSETLRVRWLLLVGLLSPALGGARSGFQQTSHLSFYEIITPWKLTRERREAPRPFSEQVSYVIQAEGKEHIIHLERNKDLLPKDFVVYTYNKEGALISDHPSIQNHCHYRGYVEGTYDSSIALSDCFGLRGLLHIENVSYGIEPLQNSSHFEHIFYRMDDVHQEPLKCGVSNKVMEEETTKDEEEEHPSITQLLRRKRDILPQTRYVELFIVVEKEKYDNMGKNQTAVREEMISLANYLDSMYIMLNIRIVLVGLEIWTNENLISMAGGAGDVLSNFVQWREKFLITRRRHDSAQLILKRGFGGTAGMAFVGTVCSRSHAGGINVFGQIPVEKFASIVAHELGHNLGMSHDDGRGCHCPVKSCIMNSGASGSKNFSSCSADDFEKLTLNKGGNCLLNIPKGDEAYSAPSCGNKLVDPGEECDCGSPKECELDPCCEGKTCKLKSFAECAYGACCQDCRFRPGGTLCRGKTNECDVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPKECFLDVNSKGDRFGNCGFSGHEYKKCAIGNALCGKLQCENVQQLPVFGVVPAIIQTPGKGTKCWGVDFQLGSDVPDPGMVNEGTSCDVGKICRNFACVNVSVLNYDCDIQQKCHGHGVCNSNKNCHCDNGWAPPNCETKGYGGSVDSGPTYNENNAALRDGLLVFFFLILPLTVLAVFVFIKRDQLRKSCCRRKRSQTNESGGKNQAKDSRQPASVPRPVSSVIPPRNVPVQTNRFPVPTYGARQPQQYPSRPPPPQPKESFQGNLVPARPAPPPPPPLYSSLT", "length": 821, "header": "tr|A0ABI0P0W2-1|A0ABI0P0W2_BOVIN Isoform 1 of ADAM metallopeptidase domain 9 OS=Bos taurus OX=9913 GN=ADAM9 PE=4 SV=1 CANONICAL=A0ABI0P0W2-1" }, "locus": { "chromosome": "27", "start_pos": 34241119, "end_pos": 34152503, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137424.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137424.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106564.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106564.1" } ] } }, { "isoform_ac": "A0ABI0P535-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0W2/entry#A0ABI0P535-1", "sequence": { "sequence": "MGSGVGSPSETLRVRWLLLVGLLSPALGGARSGFQQTSHLSFYEIITPWKLTRERREAPRPFSEQVSYVIQAEGKEHIIHLERNKDLLPKDFVVYTYNKEGALISDHPSIQNHCHYRGYVEGTYDSSIALSDCFGLRGLLHIENVSYGIEPLQNSSHFEHIFYRMDDVHQEPLKCGVSNKVMEEETTKDEEEEHPSITQLLRRKRDILPQTRYVELFIVVEKEKYDNMGKNQTAVREEMISLANYLDSMYIMLNIRIVLVGLEIWTNENLISMAGGAGDVLSNFVQWREKFLITRRRHDSAQLILKRGFGGTAGMAFVGTVCSRSHAGGINVFGQIPVEKFASIVAHELGHNLGMSHDDGRGCHCPVKSCIMNSGASGSKNFSSCSADDFEKLTLNKGGNCLLNIPKGDEAYSAPSCGNKLVDPGEECDCGSPKECELDPCCEGKTCKLKSFAECAYGACCQDCRFRPGGTLCRGKTNECDVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPKECFLDVNSKGDRFGNCGFSGHEYKKCAIGNALCGKLQCENVQQLPVFGVVPAIIQTPGKGTKCWGVDFQLGSDVPDPGMVNEGTSCDVGKICRNFACVNVSVLNYDCDIQQKCHGHGPVQTNRFPVPTYGARQPQQYPSRPPPPQPKESFQGNLVPARPAPPPPPPLYSSLT", "length": 709, "header": "tr|A0ABI0P535-1|A0ABI0P535_BOVIN Computationally mapped isoform of ADAM metallopeptidase domain 9 OS=Bos taurus OX=9913 GN=ADAM9 PE=4 SV=1 CANONICAL=A0ABI0P0W2-1" }, "locus": { "chromosome": "27", "start_pos": 34241119, "end_pos": 34152503, "strand": "-", 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"id": "ENSBTAG00000046324", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046324", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100297676", "url": "https://www.ncbi.nlm.nih.gov/gene/100297676", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100297676", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100297676", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "bta:784451", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784451", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR45710", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45710", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45710:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45710:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SF73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SF73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SF73-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SF73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T600", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T600", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T600-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T600-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLB1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLB1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPR6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPR6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1B7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1B7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BH08", "url": "https://www.uniprot.org/uniprotkb/E1BH08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BH08-1", "url": "https://www.uniprot.org/uniprotkb/E1BH08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX70", "url": "https://www.uniprot.org/uniprotkb/G3MX70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX70-1", "url": "https://www.uniprot.org/uniprotkb/G3MX70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWEIAADLSARRRGMWSPHRNMTSTEVFLKILETDPTYRENTEAWRSGKGLQKKCLAITSSVTPATLCCCILIILILVALNVVTLSVLLAVRSRETDLQVVYVTCPKGWIGFGNKCFYFSEDSENWTLSQISCTSVGAVLAQFETEEELNFLTRYKDIFDYWIGLSRESSHHAWKWTDNSKLNVPFVIQGTGECAYLTDSGVSSGKRYVIRKRICSKTNSNVSISLDAL", "length": 229, "header": "tr|A0ABI0P1B7-1|A0ABI0P1B7_BOVIN Isoform 1 of C-type lectin domain-containing protein OS=Bos taurus OX=9913 GN=CLEC2D PE=4 SV=1 CANONICAL=A0ABI0P1B7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SF73-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7/entry#A0AAA9SF73-1", "sequence": { "sequence": "MTSTEVFLKILETDPTYRENTEAWRSGKGLQKKCLAITSSVTPATLCCCILIILILVALNVVTLSVLLAVRSRETDLQVVYVTCPKGWIGFGNKCFYFSEDSENWTLSQISCTSVGAVLAQFETEEELNFLTRYKDIFDYWIGLSRESSHHAWKWTDNSKLNVPFVIQGTGECAYLTDSGVSSGKRYVIRKRICSKTNRDWNTKARSQETPGVTCKFGLGV", "length": 221, "header": "tr|A0AAA9SF73-1|A0ABI0P1B7_BOVIN Computationally mapped isoform of C-type lectin domain-containing protein OS=Bos taurus OX=9913 GN=CLEC2D PE=4 SV=2 CANONICAL=A0ABI0P1B7-1" }, "locus": { "chromosome": "5", "start_pos": 100494922, "end_pos": 100471679, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126025.2", "url": "https://www.ensembl.org/id/ENSBTAT00000126025.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081094.2", "url": "https://www.ensembl.org/id/ENSBTAP00000081094.2" } ] } }, { "isoform_ac": "A0AAA9T600-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7/entry#A0AAA9T600-1", "sequence": { "sequence": "MTSTEVFLKILETDPTYRENTEAWRSGKGLQKKCLAITSSVTPATLCCCILIILILVALNVVTLSVLLAVRSRETDLQVVYVTCPKGWIGFGNKCFYFSEDSENWTLSQISCTSVGAVLAQFETEEELNFLTRYKDIFDYWIGLSRESSHHAWKWTDNSKLNVPIVLVLPYINMNPNEKNRPAHTERICHPRNWRMCLPD", "length": 200, "header": "tr|A0AAA9T600-1|A0ABI0P1B7_BOVIN Computationally mapped isoform of C-type lectin domain-containing protein OS=Bos taurus OX=9913 GN=CLEC2D PE=4 SV=1 CANONICAL=A0ABI0P1B7-1" }, "locus": { "chromosome": "5", "start_pos": 100494922, "end_pos": 100483886, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097005.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097005.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093284.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093284.1" } ] } }, { "isoform_ac": "A0ABI0NLB1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7/entry#A0ABI0NLB1-1", "sequence": { "sequence": "MTSTEVFLKILETDPTYRENTEAWRSGKGLQKKCLAITSSVTPATLCCCILIILILVALNVVTLSVLLAVRSRETDLQVVYVTCPKGWIGFGNKCFYFSEDSENWTLSQISCTSVGAVLAQFETEEELNFLTRYKDIFDYWIGLSRESSHHAWKWTDNSKLNVPFVIQGTGECAYLTDSGVSSGKRYVIRKRICSKTNSNVSISLDAL", "length": 208, "header": "tr|A0ABI0NLB1-1|A0ABI0P1B7_BOVIN Computationally mapped isoform of C-type lectin domain-containing protein OS=Bos taurus OX=9913 GN=CLEC2D PE=4 SV=1 CANONICAL=A0ABI0P1B7-1" }, "locus": { "chromosome": "5", "start_pos": 100494922, "end_pos": 100483792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145393.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145393.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105811.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105811.1" } ] } }, { "isoform_ac": "A0ABI0NPR6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7/entry#A0ABI0NPR6-1", "sequence": { "sequence": "PQIYLRGGEGCGHPTGKGLQKKCLAITSSVTPATLCCCILIILILVALNVVTLSVLLAVRSRETDLQVVYVTCPKGWIGFGNKCFYFSEDSENWTLSQISCTSVGAVLAQFETEEELNFLTRYKDIFDYWIGLSRESSHHAWKWTDNSKLNVPFVIQGTGECAYLTDSGVSSGKRYVIRKRICSKTNSNVSISLDAL", "length": 197, "header": "tr|A0ABI0NPR6-1|A0ABI0P1B7_BOVIN Computationally mapped isoform of C-type lectin domain-containing protein OS=Bos taurus OX=9913 GN=CLEC2D PE=4 SV=1 CANONICAL=A0ABI0P1B7-1" }, "locus": { "chromosome": "5", "start_pos": 100498437, "end_pos": 100483792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138547.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138547.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105137.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105137.1" } ] } }, { "isoform_ac": "A0ABI0P1B7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7/entry#A0ABI0P1B7-1", "sequence": { "sequence": "MWEIAADLSARRRGMWSPHRNMTSTEVFLKILETDPTYRENTEAWRSGKGLQKKCLAITSSVTPATLCCCILIILILVALNVVTLSVLLAVRSRETDLQVVYVTCPKGWIGFGNKCFYFSEDSENWTLSQISCTSVGAVLAQFETEEELNFLTRYKDIFDYWIGLSRESSHHAWKWTDNSKLNVPFVIQGTGECAYLTDSGVSSGKRYVIRKRICSKTNSNVSISLDAL", "length": 229, "header": "tr|A0ABI0P1B7-1|A0ABI0P1B7_BOVIN Isoform 1 of C-type lectin domain-containing protein OS=Bos taurus OX=9913 GN=CLEC2D PE=4 SV=1 CANONICAL=A0ABI0P1B7-1" }, "locus": { "chromosome": "5", "start_pos": 100498450, "end_pos": 100483792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152904.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152904.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106749.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106749.1" } ] } }, { "isoform_ac": "E1BH08-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7/entry#E1BH08-1", "sequence": { "sequence": "MTSTEVFLKILETDPTYRENTEAWRSGKGLQKKCLAITSSVTPATLCCCILIILILVALNVVTLSVLLAVRSRETDLQVVYVTCPKGWIGFGNKCFYFSEDSENWTLSQISCTSVGAVLAQFETEEELNFLTRYKDIFDYWIGLSRESSHHAWKWTDNSKLNVPFVIQGTGECAYLTDSGVSSGKRYVIRKRICSKTNKYFCHHIDHESERT", "length": 212, "header": "tr|E1BH08-1|A0ABI0P1B7_BOVIN Computationally mapped isoform of C-type lectin domain-containing protein OS=Bos taurus OX=9913 GN=CLEC2D PE=4 SV=5 CANONICAL=A0ABI0P1B7-1" }, "locus": { "chromosome": "5", "start_pos": 100494922, "end_pos": 100457859, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009016.8", "url": "https://www.ensembl.org/id/ENSBTAT00000009016.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009016.8", "url": "https://www.ensembl.org/id/ENSBTAP00000009016.8" } ] } }, { "isoform_ac": "G3MX70-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7/entry#G3MX70-1", "sequence": { "sequence": "MSYYNLMRFVLQGKGLQKKCLAITSSVTPATLCCCILIILILVALNVVTLSVLLAVRSRETDLQVVYVTCPKGWIGFGNKCFYFSEDSENWTLSQISCTSVGAVLAQFETEEELNFLTRYKDIFDYWIGLSRESSHHAWKWTDNSKLNVPFVIQGTGECAYLTDSGVSSGKRYVIRKRICSKTNSNVSISLDAL", "length": 194, "header": "tr|G3MX70-1|A0ABI0P1B7_BOVIN Computationally mapped isoform of C-type lectin domain-containing protein OS=Bos taurus OX=9913 GN=CLEC2D PE=4 SV=3 CANONICAL=A0ABI0P1B7-1" }, "locus": { "chromosome": "5", "start_pos": 100494163, "end_pos": 100483792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063840.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063840.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054130.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054130.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 63, "start_aa": "Thr", "end_pos": 63, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr63", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100297676", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100297676", "resource": "KEGG Pathway" }, { "id": "bta:784451", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784451", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1B7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1B7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1B7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7" } ], "pmid": "" }, { "name": "natural killer cell lectin-like receptor binding", "id": "GO:0046703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046703", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1B7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7" } ], "pmid": "" }, { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1B7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1B7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7" } ], "pmid": "" }, { "name": "NK T cell activation", "id": "GO:0051132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051132", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1B7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P1B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1B7" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 112, "end_pos": 201, "start_aa": "Phe", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 63 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P349-1", "uniprot_ac": "A0ABI0P349", "uniprot_id": "A0ABI0P349_BOVIN", "mass": { "chemical_mass": 26869.0, "monoisotopic_mass": 26869.0 }, "refseq": {}, "gene_names": [ { "name": "SREK1IP1", "type": "recommended", "evidence": [ { "id": "A0ABI0P349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P349" } ] } ], "protein_names": [ { "name": "Protein SREK1IP1", "type": "recommended", "evidence": [ { "id": "A0ABI0P349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P349/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Possible splicing regulator involved in the control of cellular survival.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SDC8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDC8#function" }, { "database": "UniProtKB", "id": "ARBA00037746", "url": "https://www.uniprot.org/uniprotkb/ARBA00037746#function" }, { "database": "UniProtKB", "id": "A0ABI0P349", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P349#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P349", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P349" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SREK1IP1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P349", "locus": { "chromosome": "20", "start_pos": 14779443, "end_pos": 14726599, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000066574", "url": "https://www.ensembl.org/id/ENSBTAG00000066574" } ] } } ], "crossref": [ { "id": "614029", "url": "https://www.ncbi.nlm.nih.gov/gene/614029", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614029", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614029", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KHHKKRQ", "url": "https://omabrowser.org/oma/group/KHHKKRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR31437", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31437", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31437:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31437:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13917", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13917", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SDC8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDC8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P349", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P349", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P349-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P349-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "WFAPCVVYKTIPPETASAATWFRNLQGLLGPSVTVKPGCRGAGGRKTAPSLVLSSRPAGSERTLRSLGVLRPLLPTPWQFQPGLLSSGCNKDSVRAGCKKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSSEESDEENEELNKLQALQEKRINEEEEKKKAKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKDKKKRKKEKHSSAPNSSEISKK", "length": 238, "header": "tr|A0ABI0P349-1|A0ABI0P349_BOVIN Isoform 1 of Protein SREK1IP1 OS=Bos taurus OX=9913 GN=SREK1IP1 PE=4 SV=1 CANONICAL=A0ABI0P349-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SDC8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P349/entry#A0AAA9SDC8-1", "sequence": { "sequence": "MAIPGCNKDSVRAGCKKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSSEESDEENEELNKLQALQEKRINEEEEKKKAKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKDKKKRKKEKHSSAPNSSEISKK", "length": 155, "header": "tr|A0AAA9SDC8-1|A0ABI0P349_BOVIN Computationally mapped isoform of Protein SREK1IP1 OS=Bos taurus OX=9913 GN=SREK1IP1 PE=4 SV=1 CANONICAL=A0ABI0P349-1" }, "locus": { "chromosome": "20", "start_pos": 14761953, "end_pos": 14726774, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115001.2", "url": "https://www.ensembl.org/id/ENSBTAT00000115001.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081560.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081560.1" } ] } }, { "isoform_ac": "A0ABI0P349-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P349/entry#A0ABI0P349-1", "sequence": { "sequence": "WFAPCVVYKTIPPETASAATWFRNLQGLLGPSVTVKPGCRGAGGRKTAPSLVLSSRPAGSERTLRSLGVLRPLLPTPWQFQPGLLSSGCNKDSVRAGCKKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSSEESDEENEELNKLQALQEKRINEEEEKKKAKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKDKKKRKKEKHSSAPNSSEISKK", "length": 238, "header": "tr|A0ABI0P349-1|A0ABI0P349_BOVIN Isoform 1 of Protein SREK1IP1 OS=Bos taurus OX=9913 GN=SREK1IP1 PE=4 SV=1 CANONICAL=A0ABI0P349-1" }, "locus": { "chromosome": "20", "start_pos": 14761953, "end_pos": 14726544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150436.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150436.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105357.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105357.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614029", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614029", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HXH9-1", "protein_name": "Protein SREK1IP1", "gene_name": "Srek1ip1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVPGCNKDNVRAGCKKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKREKSKEKLKLKKKRKRSYSSSTEEDSSKQKKQKYQKKEKKKERKNKSKKGKHHKKEKKKRKKEKRSSPNRSEVTKK", "length": 153 }, "evidence": [ { "id": "A0ABI0P349", "url": "https://omabrowser.org/oma/group/A0ABI0P349/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3B7G7-1", "protein_name": "Protein SREK1IP1", "gene_name": "srek1ip1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAPGPNKDNIRAGCKRCGYPGHLTFECRNFLRVDPRKDIVLDVSSTSTEESDEEEQEALSKEKIFGSHSKGSQEDSRKEKHKKKSKERSRGKAKKRSYSSSDEEEDEMSKKKKKRKSNKKKGKKEKREKERKHKKKQKKKDTESSSSDSSSESSDTD", "length": 158 }, "evidence": [ { "id": "A0ABI0P349", "url": "https://omabrowser.org/oma/group/A0ABI0P349/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q4V9W2-1", "protein_name": "Protein SREK1IP1", "gene_name": "Srek1ip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVPGCNKDNVRAGCRKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSREKIKLKKRRKRSYSSATEEDSAKQKKQKYQKKEKKKEKKNKSKKGKHHKKEKKKRKKEKRSSPYHSELTKK", "length": 153 }, "evidence": [ { "id": "A0ABI0P349", "url": "https://omabrowser.org/oma/group/A0ABI0P349/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RJP9-1", "protein_name": "Protein SREK1IP1", "gene_name": "Srek1ip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVPGCNKDNVRAGCRKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEESEELNKLQALQEKRINEEEEKKKEKSREKIKLKKKRKRSNSSTTEEDSSKQKKQKYQKKEKKKEKKNKSKKGKHHKKEKKKRKKEKRSSPNRSEVTKK", "length": 153 }, "evidence": [ { "id": "A0ABI0P349", "url": "https://omabrowser.org/oma/group/A0ABI0P349/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N9Q2-1", "protein_name": "Protein SREK1IP1", "gene_name": "SREK1IP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVPGCNKDSVRAGCKKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK", "length": 155 }, "evidence": [ { "id": "A0ABI0P349", "url": "https://omabrowser.org/oma/group/A0ABI0P349/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SJV6-1", "protein_name": "FAM133-like protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDCKKFIQMVEEKKRRVLEKQEAPLKWEQKLEAAANAKADTETKVKRSKGPKRKQRAASESSSESDSSSEVRRKSRRSHNKHRRHAHSDSDDSDRRKEKKSRRQKRRSLSPSDDSTGDYESGSEDELRMKIKHHRRHKWHSSRKTCDDDSTEDVRRKHLKHHRRSEVVTSSDSEEESGRRRRGKYHRHNRGSASSSGSEEDSGKSMKRRQHKRHRLAESSSEEDGAMRRTRHHKHGRDSASESDGRR", "length": 247 }, "evidence": [ { "id": "A0ABI0P349", "url": "https://omabrowser.org/oma/group/A0ABI0P349/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P349", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P349" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P349", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P349" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P349" }, { "id": "PS50158", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50158" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCHC-type", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 113, "start_aa": "Cys", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 231, "end_pos": 233 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P467-1", "uniprot_ac": "A0ABI0P467", "uniprot_id": "A0ABI0P467_BOVIN", "mass": { "chemical_mass": 137653.0, "monoisotopic_mass": 137653.0 }, "refseq": { "ac": "XP_003587743", "name": "superkiller complex protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587743" }, "gene_names": [ { "name": "SKIC2", "type": "recommended", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] }, { "name": "SKIC2", "type": "synonym", "evidence": [ { "id": "XP_003587743", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587743" } ] } ], "protein_names": [ { "name": "Superkiller complex protein 2", "type": "recommended", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467/entry#names_and_taxonomy" } ] }, { "name": "superkiller complex protein 2", "type": "synonym", "evidence": [ { "id": "XP_003587743", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587743" } ] } ], "function": [ { "annotation": "Helicase component of the SKI complex, a multiprotein complex that assists the RNA-degrading exosome during the mRNA decay and quality-control pathways. The SKI complex catalyzes mRNA extraction from 80S ribosomal complexes in the 3'-5' direction and channels mRNA to the cytosolic exosome for degradation. SKI-mediated extraction of mRNA from stalled ribosomes allow binding of the Pelota-HBS1L complex and subsequent ribosome disassembly by ABCE1 for ribosome recycling. In the nucleus, the SKI complex associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C). May play a role in the non-stop mRNA decay pathway (NSD), which specifically targets and degrades mRNAs that lack a proper stop codon.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SE27", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE27#function" }, { "database": "UniProtKB", "id": "ARBA00094484", "url": "https://www.uniprot.org/uniprotkb/ARBA00094484#function" }, { "database": "UniProtKB", "id": "A0AAA9T275", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T275#function" }, { "database": "UniProtKB", "id": "A0ABI0P467", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P467", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SKIC2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467", "locus": { "chromosome": "23", "start_pos": 27398291, "end_pos": 27409441, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005587", "url": "https://www.ensembl.org/id/ENSBTAG00000005587" } ] } } ], "crossref": [ { "id": "ENSBTAG00000005587", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005587", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18027", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18027", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18795", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18795", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100139548", "url": "https://www.ncbi.nlm.nih.gov/gene/100139548", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100139548", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100139548", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BMS0", "url": "https://www.orthodb.org/?gene=E1BMS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12131:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12131:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08148", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08148", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13234", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13234", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17911", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17911", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21408", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21408", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-429958", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-429958", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003587743", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587743", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SE27", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SE27-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNN8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNN8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T275", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T275", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T275-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T275-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P467", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P467-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMS0", "url": "https://www.uniprot.org/uniprotkb/E1BMS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BMS0-1", "url": "https://www.uniprot.org/uniprotkb/E1BMS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMETERLVLPPPDPLDLPLRAVELGCTGRWELLNVPGAPESTLPHGLPPCAPDLQQEAERLFLSSPAWLPLHGVEHSAREWQRKMDPWSLLATLGAPVPSDLQAQRHPTTGQILGYKEVLLENTNLSSTTSLSLRRPPAPISQSLWGNPTQYPFWPGGMDEPSITDLSTREEAEEEIDFEKDLLTLPPGFKKGVDFAPKGHSAPAAGLLSLSRLLEPLDLGGGDEDESEAVGQPGGPRQDTVSASPGSVPLARASSLEDLVLKEAATTVAPPEPPKPPPQEQWAIPVDVTSPVGDFYRLIPQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVARPVPLEHYLFTGNSPKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLHRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKKLGALEEPEVTGQLVDLPEYYSWGEELTETRSQIQHRIIESVNGLKSLSAGRVVVVKNQEHHNALGVILQVSSNSTSRVFTALVLCDKPVSEDPRERGPASPDVPYPDDLVGFKLFLPEGPCDHTVAKLQPGDVAAITTKVLRLNGDKILEDFSKRQQPKFKKDPPSAAVTTAVQELLRLAQAHPTGPPTLDPVNDLQLKDVSVVEGGLRARKLEELIRGAQCVHSPRFPAQYLKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMSSHELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDPGDQLPSTLKQGVERVRTVAKRIGEVQAACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLYTQ", "length": 1246, "header": "tr|A0ABI0P467-1|A0ABI0P467_BOVIN Isoform 1 of Superkiller complex protein 2 OS=Bos taurus OX=9913 GN=SKIC2 PE=3 SV=1 CANONICAL=A0ABI0P467-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SE27-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467/entry#A0AAA9SE27-1", "sequence": { "sequence": "MMETERLVLPPPDPLDLPLRAVELGCTGRWELLNVPGAPESTLPHGLPPCAPDLQQEAERLFLSSPAWLPLHGVEHSAREWQRKMDPWSLLATLGAPVPSDLQAQRHPTTGQILGYKEVLLENTNLSSTTSLSLRRPPAPISQSLWGNPTQYPFWPGGMDEPSITDLSTREEAEEEIDFEKDLLTLPPGFKKGVDFAPKGHSAPAAGLLSLSRLLEPLDLGGGDEDESEAVGQPGGPRQDTVSASPGSVPLARASSLEDLVLKEAATTVAPPEPPKPPPQEQWAIPVDVTSPVGDFYRLIPQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVARPVPLEHYLFTGNSPKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLHRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKKLGALEEPEVTGQLVDLPEYYSWGEELTETRSQIQVSSNSTSRVFTALVLCDKPVSEDPRERGPASPDVPYPDDLVGFKLFLPEGPCDHTVAKLQPGDVAAITTKVLRLNGDKILEDFSKRQQPKFKKDPPSAAVTTAVQELLRLAQAHPTGPPTLDPVNDLQLKDVSVVEGGLRARKLEELIRGAQCVHSPRFPAQYLKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMSSHELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDPGDQLPSTLKQGVERVRTVAKRIGEVQAACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLYTQ", "length": 1211, "header": "tr|A0AAA9SE27-1|A0ABI0P467_BOVIN Computationally mapped isoform of Superkiller complex protein 2 OS=Bos taurus OX=9913 GN=SKIC2 PE=3 SV=1 CANONICAL=A0ABI0P467-1" }, "locus": { "chromosome": "23", "start_pos": 27409242, "end_pos": 27399295, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120731.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120731.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081843.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081843.1" } ] } }, { "isoform_ac": "A0AAA9SNN8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467/entry#A0AAA9SNN8-1", "sequence": { "sequence": "MMETERLVLPPPDPLDLPLRAVELGCTGRWELLNVPGAPESTLPHGLPPCAPDLQQEAERLFLSSPAWLPLHGVEHSAREWQRKMDPWSLLATLGAPVPSDLQAQRHPTTGQILGYKEVLLENTNLSSTTSLSLRRPPAPISQSLWGNPTQYPFWPGGMDEPSITDLSTREEAEEEIDFEKDLLTLPPGFKKGVDFAPKGHSAPAAGLLSLSRLLEPLDLGGGDEDESEAVGQPGGPRQDTVSASPGSVPLARASSLEDLVLKEAATTVAPPEPPKPPPQEQWAIPVDVTSPVGDFYRLIPQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVARPVPLEHYLFTGNSPKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLHRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKKLGALEEPEVTGQLVDLPEYYSWGEELTETRSQIQHRIIESVNGLKSLSAGRVVVVKNQEHHNALGVILQVSSNSTSRVFTALVLCDKPVSEDPRERGPASPDVPYPDDLVGFKLFLPEGPCDHTVAKLQPGDVAAITTKVLRLNGDKILEDFSKRQQPKFKKDPPSAAVTTAVQELLRLAQAHPTGPPTLDPVNDLQLKDVSVVEGGLRARKLEELIRGAQCVHSPRFPAQYLKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMSSHELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDPGDQLPSTLKQPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLYTQ", "length": 1199, "header": "tr|A0AAA9SNN8-1|A0ABI0P467_BOVIN Computationally mapped isoform of Superkiller complex protein 2 OS=Bos taurus OX=9913 GN=SKIC2 PE=3 SV=1 CANONICAL=A0ABI0P467-1" }, "locus": { "chromosome": "23", "start_pos": 27409242, "end_pos": 27399295, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134622.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134622.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084480.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084480.1" } ] } }, { "isoform_ac": "A0AAA9T275-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467/entry#A0AAA9T275-1", "sequence": { "sequence": "MMETERLDLQQEAERLFLSSPAWLPLHGVEHSAREWQRKMDPWSLLATLGAPVPSDLQAQRHPTTGQILGYKEVLLENTNLSSTTSLSLRRPPAPISQSLWGNPTQYPFWPGGMDEPSITDLSTREEAEEEIDFEKDLLTLPPGFKKGVDFAPKGHSAPAAGLLSLSRLLEPLDLGGGDEDESEAVGQPGGPRQDTVSASPGSVPLARASSLEDLVLKEAATTVAPPEPPKPPPQEQWAIPVDVTSPVGDFYRLIPQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVARPVPLEHYLFTGNSPKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLHRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKKLGALEEPEVTGQLVDLPEYYSWGEELTETRSQIQHRIIESVNGLKSLSAGRVVVVKNQEHHNALGVILQVSSNSTSRVFTALVLCDKPVSEDPRERGPASPDVPYPDDLVGFKLFLPEGPCDHTVAKLQPGDVAAITTKVLRLNGDKILEDFSKRQQPKFKKDPPSAAVTTAVQELLRLAQAHPTGPPTLDPVNDLQLKDVSVVEGGLRARKLEELIRGAQCVHSPRFPAQYLKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMSSHELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDPGDQLPSTLKQGVERVRTVAKRIGEVQAACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLYTQ", "length": 1201, "header": "tr|A0AAA9T275-1|A0ABI0P467_BOVIN Computationally mapped isoform of Superkiller complex protein 2 OS=Bos taurus OX=9913 GN=SKIC2 PE=3 SV=1 CANONICAL=A0ABI0P467-1" }, "locus": { "chromosome": "23", "start_pos": 27409242, "end_pos": 27399295, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091907.2", "url": "https://www.ensembl.org/id/ENSBTAT00000091907.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092898.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092898.1" } ] } }, { "isoform_ac": "A0ABI0P467-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467/entry#A0ABI0P467-1", "sequence": { "sequence": "MMETERLVLPPPDPLDLPLRAVELGCTGRWELLNVPGAPESTLPHGLPPCAPDLQQEAERLFLSSPAWLPLHGVEHSAREWQRKMDPWSLLATLGAPVPSDLQAQRHPTTGQILGYKEVLLENTNLSSTTSLSLRRPPAPISQSLWGNPTQYPFWPGGMDEPSITDLSTREEAEEEIDFEKDLLTLPPGFKKGVDFAPKGHSAPAAGLLSLSRLLEPLDLGGGDEDESEAVGQPGGPRQDTVSASPGSVPLARASSLEDLVLKEAATTVAPPEPPKPPPQEQWAIPVDVTSPVGDFYRLIPQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVARPVPLEHYLFTGNSPKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLHRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKKLGALEEPEVTGQLVDLPEYYSWGEELTETRSQIQHRIIESVNGLKSLSAGRVVVVKNQEHHNALGVILQVSSNSTSRVFTALVLCDKPVSEDPRERGPASPDVPYPDDLVGFKLFLPEGPCDHTVAKLQPGDVAAITTKVLRLNGDKILEDFSKRQQPKFKKDPPSAAVTTAVQELLRLAQAHPTGPPTLDPVNDLQLKDVSVVEGGLRARKLEELIRGAQCVHSPRFPAQYLKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMSSHELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDPGDQLPSTLKQGVERVRTVAKRIGEVQAACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLYTQ", "length": 1246, "header": "tr|A0ABI0P467-1|A0ABI0P467_BOVIN Isoform 1 of Superkiller complex protein 2 OS=Bos taurus OX=9913 GN=SKIC2 PE=3 SV=1 CANONICAL=A0ABI0P467-1" }, "locus": { "chromosome": "23", "start_pos": 27409242, "end_pos": 27399295, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145238.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145238.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106068.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106068.1" } ] } }, { "isoform_ac": "E1BMS0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467/entry#E1BMS0-1", "sequence": { "sequence": "MMETERLVLPPPDPLDLPLRAVELGCTGRWELLNVPGAPESTLPHGLPPCAPDLQQEAERLFLSSPAWLPLHGVEHSAREWQRKMDPWSLLATLGAPVPSDLQAQRHPTTGQILGYKEVLLENTNLSSTTSLSLRRPPAPISQSLWGNPTQYPFWPGGMDEPSITDLSTREEAEEEIDFEKDLLTLPPGFKKGVDFAPKGHSAPAAGLLSLSRLLEPLDLGGGDEDESEAVGQPGGPRQDTVSASPGSVPLARASSLEDLVLKEAATTVAPPEPPKPPPQEQWAIPVDVTSPVGDFYRLIPQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVARPVPLEHYLFTGNSPKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLHRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKKLGALEEPEVTGQLVDLPEYYSWGEELTETRSQIQHRIIESVNGLKSLSAGRVVVVKNQEHHNALGVILQVSSNSTSRVFTALVLCDKPVSEDPRERGPASPDVPYPDDLVGFKLFLPEGPCDHTVAKLQPGDVAAITTKVLRLNGDKILEDFSKRQQPKFKKDPPSAAVTTAVQELLRLAQAHPTGPPTLDPVNDLQLKDVSVVEGGLRARKLEELIRGAQCVHSPRFPAQYLKLRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMSSHELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDPGDQLPSTLKQGVERVRTVAKRIGEVQAACGLNQTVEEFVGELNFGLVEVVYEWARGMVSSW", "length": 1184, "header": "tr|E1BMS0-1|A0ABI0P467_BOVIN Computationally mapped isoform of Superkiller complex protein 2 OS=Bos taurus OX=9913 GN=SKIC2 PE=3 SV=3 CANONICAL=A0ABI0P467-1" }, "locus": { "chromosome": "23", "start_pos": 27409242, "end_pos": 27399576, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007339.7", "url": "https://www.ensembl.org/id/ENSBTAT00000007339.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007339.6", "url": "https://www.ensembl.org/id/ENSBTAP00000007339.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:100139548", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100139548", "resource": "KEGG Pathway" }, { "id": "R-BTA-429958", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-429958", "resource": "Reactome", "description": "mRNA decay by 3' to 5' exoribonuclease" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P467", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P467", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P467", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P467", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P467", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P467", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ], "pmid": "" }, { "name": "Ski complex", "id": "GO:0055087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055087", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P467", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P467", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ], "pmid": "" }, { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P467", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay", "id": "GO:0070478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070478", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P467", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1155, "end_pos": 1157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 865, "end_pos": 867, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", "F1N2W9-1", "E1BB03-1", "E1BMP7-1", "A0JND9-1", "E1BAS6-1", "A0AAA9RXM7-1", "Q59HJ6-1", "Q2KJ94-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "A0AAF6Z0E4-1", "G3MZH7-1", "F1MKC7-1", "A0AAA9S7V9-1", "A0AAF6YME1-1", "F1MFR1-1", "Q3T084-1", "E1B7X9-1", "A0ABI0P204-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LG16", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] } ] }, { "uniprot_ac": "A0A3Q1LQC3", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] } ] }, { "uniprot_ac": "A0A3Q1LSH0", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] } ] }, { "uniprot_ac": "A0A3Q1LT80", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] } ] }, { "uniprot_ac": "A0A3Q1LTL4", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] } ] }, { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1LXD0", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": 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{ "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDD8" } ] } ] }, { "uniprot_ac": "A0A3Q1MR04", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MR04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR04" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A3Q1MR04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR04" } ] } ] }, { "uniprot_ac": "A0A3Q1MR43", "gene_name": "DDX46", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MR43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1MR43", "database": "UniProtKB", "url": 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H(+).", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] } ] }, { "uniprot_ac": "A0JND9", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] } ] }, { "uniprot_ac": "A1A4H6", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A1A4H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4H6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A1A4H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4H6" } ] } ] }, { "uniprot_ac": "A4FUD9", "gene_name": "MCM3", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A4FUD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FUD9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A4FUD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FUD9" } ] } ] }, { "uniprot_ac": "A4K436", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A4K436", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4K436" } ] } ] }, { "uniprot_ac": "A5D7C1", "gene_name": "DDX52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] } ] }, { "uniprot_ac": "A5PJA1", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] } ] }, { "uniprot_ac": "A5PJI5", "gene_name": "GET3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A5PJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJI5" } ] } ] }, { "uniprot_ac": "A6QLE5", "gene_name": "NLRP3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A6QLE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLE5" } ] } ] }, { "uniprot_ac": "A6QLJ0", "gene_name": "ERCC2", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] } ] }, { "uniprot_ac": "A6QQR4", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] } ] }, { "uniprot_ac": "A7YSY2", "gene_name": "AFG2B", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] } ] }, { "uniprot_ac": "A7Z019", "gene_name": "SMARCA4", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A7Z019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7Z019" } ] } ] }, { "uniprot_ac": "E1B7X9", "gene_name": "SMARCAD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1B7X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7X9" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B9N7", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] } ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BAN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAN8" } ] } ] }, { "uniprot_ac": "E1BAS6", "gene_name": "SETX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] } ] }, { "uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "O18956", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] } ] }, { "uniprot_ac": "P09487", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.9.1.1", "activity": "N-phosphocreatine + H2O = creatine + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] } ] }, { "uniprot_ac": "P19120", "gene_name": "HSPA8", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] } ] }, { "uniprot_ac": "P35071", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "P35071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35071" } ] } ] }, { "uniprot_ac": "P60712", "gene_name": "ACTB", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P60712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P60712" } ] } ] }, { "uniprot_ac": "P62739", "gene_name": "ACTA2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P62739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62739" } ] } ] }, { "uniprot_ac": "P63258", "gene_name": "ACTG1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P63258" } ] } ] }, { "uniprot_ac": "P68138", "gene_name": "ACTA1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68138" } ] } ] }, { "uniprot_ac": "Q05B79", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] } ] }, { "uniprot_ac": "Q0IIK5", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + 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"domain_list": [ { "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 319, "end_pos": 475, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" }, { "id": "PS51194", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase C-terminal", "eco_id": "ECO_0000259", "start_pos": 585, "end_pos": 755, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.4.13", "ec_name": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "3.6.4.13", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13" }, { "id": "3.6.4.13", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.4.13" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1155, "end_pos": 1157 }, { "start_pos": 125, "end_pos": 127 }, { "start_pos": 865, "end_pos": 867 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P2G7-1", "uniprot_ac": "A0ABI0P2G7", "uniprot_id": "A0ABI0P2G7_BOVIN", "mass": { "chemical_mass": 31241.0, "monoisotopic_mass": 31241.0 }, "refseq": {}, "gene_names": [ { "name": "FAM107A", "type": "recommended", "evidence": [ { "id": "A0ABI0P2G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7" } ] } ], "protein_names": [ { "name": "Actin-associated protein FAM107A", "type": "recommended", "evidence": [ { "id": "A0ABI0P2G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin) dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory. Plays a role in the actin and microtubule cytoskeleton organization; negatively regulates focal adhesion (FA) assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner. Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner. May play a role in tumor development.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SGX4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGX4#function" }, { "database": "UniProtKB", "id": "ARBA00045129", "url": "https://www.uniprot.org/uniprotkb/ARBA00045129#function" }, { "database": "UniProtKB", "id": "A0AAA9TKC3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKC3#function" }, { "database": "UniProtKB", "id": "A0AAA9TKX7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKX7#function" }, { "database": "UniProtKB", "id": "A0AAA9SJ62", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ62#function" }, { "database": "UniProtKB", "id": "A0ABI0P2G7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2G7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM107A", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7", "locus": { "chromosome": "22", "start_pos": 42816148, "end_pos": 42724291, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000069842", "url": "https://www.ensembl.org/id/ENSBTAG00000069842" } ] } } ], "crossref": [ { "id": "538515", "url": "https://www.ncbi.nlm.nih.gov/gene/538515", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MNHRRGI", "url": "https://omabrowser.org/oma/group/MNHRRGI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16768", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16768", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16768:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16768:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SGX4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGX4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJ62", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJ62-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKC3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKC3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKX7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKX7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2G7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2G7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTCLLARLLYTLACRSGTFCFRNVRPNARFDDSVNISGLFFLEAGQPQGLQTCGGSPVPSLLPPPVITGLFPTSKEYSPQAIFHNENEKQRLNGSGSCTDLHPSLVYLENCCSSCREWHHPLPRASMYSEIQRERADIGGLMARPEHREWNPELIKPKKLLNPVKASRNHQEMHRELLMNHRRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEKEEDHAPEFIKVRENLRRITTLTSGERAL", "length": 270, "header": "tr|A0ABI0P2G7-1|A0ABI0P2G7_BOVIN Isoform 1 of Actin-associated protein FAM107A OS=Bos taurus OX=9913 GN=FAM107A PE=4 SV=1 CANONICAL=A0ABI0P2G7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SGX4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7/entry#A0AAA9SGX4-1", "sequence": { "sequence": "MNRPVEAAPPGSPGTLVERGPAALRSEVLFPRTRAQLRTSMYSEIQRERADIGGLMARPEHREWNPELIKPKKLLNPVKASRNHQEMHRELLMNHRRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQTLYPQQPRAAAAPLLEVRTALCELYCACALPGPSAGRRLLIPQAGVRAENLVSNKLLDRRAEAHTVPGKAGASRGGE", "length": 226, "header": "tr|A0AAA9SGX4-1|A0ABI0P2G7_BOVIN Computationally mapped isoform of Actin-associated protein FAM107A OS=Bos taurus OX=9913 GN=FAM107A PE=4 SV=1 CANONICAL=A0ABI0P2G7-1" }, "locus": { "chromosome": "22", "start_pos": 42815055, "end_pos": 42794163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106091.2", "url": "https://www.ensembl.org/id/ENSBTAT00000106091.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083151.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083151.1" } ] } }, { "isoform_ac": "A0AAA9SJ62-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7/entry#A0AAA9SJ62-1", "sequence": { "sequence": "MTCLLARLLYTLACRSGTFCFRNVRPNARFDDSVNISGLFFLEAGQPQGLQTCGGSPVPSLLPPPVITGLFPTSKEYSPQAIFHNENEKQRLNGSASMYSEIQRERADIGGLMARPEHREWNPELIKPKKLLNPVKASRNHQEMHRELLMNHRRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEKEEDHAPEFIKVRENLRRITTLTSGERAL", "length": 241, "header": "tr|A0AAA9SJ62-1|A0ABI0P2G7_BOVIN Computationally mapped isoform of Actin-associated protein FAM107A OS=Bos taurus OX=9913 GN=FAM107A PE=4 SV=1 CANONICAL=A0ABI0P2G7-1" }, "locus": { "chromosome": "22", "start_pos": 42814193, "end_pos": 42734636, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091241.2", "url": "https://www.ensembl.org/id/ENSBTAT00000091241.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085376.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085376.1" } ] } }, { "isoform_ac": "A0AAA9TKC3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7/entry#A0AAA9TKC3-1", "sequence": { "sequence": "MGAAQGKKKEYSPQAIFHNENEKQRLNGSASMYSEIQRERADIGGLMARPEHREWNPELIKPKKLLNPVKASRNHQEMHRELLMNHRRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEKEEDHAPEFIKVRENLRRITTLTSGERAL", "length": 175, "header": "tr|A0AAA9TKC3-1|A0ABI0P2G7_BOVIN Computationally mapped isoform of Actin-associated protein FAM107A OS=Bos taurus OX=9913 GN=FAM107A PE=4 SV=1 CANONICAL=A0ABI0P2G7-1" }, "locus": { "chromosome": "22", "start_pos": 42814193, "end_pos": 42724490, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134899.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134899.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097369.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097369.1" } ] } }, { "isoform_ac": "A0AAA9TKX7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7/entry#A0AAA9TKX7-1", "sequence": { "sequence": "MAQRLGERVRGPTEATGLYRAVLLRSASMYSEIQRERADIGGLMARPEHREWNPELIKPKKLLNPVKASRNHQEMHRELLMNHRRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEKEEDHAPEFIKVRENLRRITTLTSGERAL", "length": 172, "header": "tr|A0AAA9TKX7-1|A0ABI0P2G7_BOVIN Computationally mapped isoform of Actin-associated protein FAM107A OS=Bos taurus OX=9913 GN=FAM107A PE=4 SV=1 CANONICAL=A0ABI0P2G7-1" }, "locus": { "chromosome": "22", "start_pos": 42814193, "end_pos": 42781147, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131204.2", "url": "https://www.ensembl.org/id/ENSBTAT00000131204.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099065.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099065.1" } ] } }, { "isoform_ac": "A0ABI0P2G7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7/entry#A0ABI0P2G7-1", "sequence": { "sequence": "MTCLLARLLYTLACRSGTFCFRNVRPNARFDDSVNISGLFFLEAGQPQGLQTCGGSPVPSLLPPPVITGLFPTSKEYSPQAIFHNENEKQRLNGSGSCTDLHPSLVYLENCCSSCREWHHPLPRASMYSEIQRERADIGGLMARPEHREWNPELIKPKKLLNPVKASRNHQEMHRELLMNHRRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEKEEDHAPEFIKVRENLRRITTLTSGERAL", "length": 270, "header": "tr|A0ABI0P2G7-1|A0ABI0P2G7_BOVIN Isoform 1 of Actin-associated protein FAM107A OS=Bos taurus OX=9913 GN=FAM107A PE=4 SV=1 CANONICAL=A0ABI0P2G7-1" }, "locus": { "chromosome": "22", "start_pos": 42814193, "end_pos": 42734636, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142038.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142038.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105247.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105247.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z9C1-1", "protein_name": "Actin-associated protein FAM107A", "gene_name": "FAM107A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLEPCQRGAGVMSEKEYSLQPRCAGSSRRPTSGSSASMYTEIQQEHSDSASILTHPDYIDGNPDLIKPKKLLNPVKASKSHQELHRELLMNHKRGLSVDSKPELQRVLEHRRRNQVLRQKKEEEEAKKLQSPFEKELLKRHQRLDQLEKEQEKQEDHAPEFIKVKENLRRTSTVTGEEKAA", "length": 181 }, "evidence": [ { "id": "A0ABI0P2G7", "url": "https://omabrowser.org/oma/group/A0ABI0P2G7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "M0R3K6-1", "protein_name": "Actin-associated protein FAM107A", "gene_name": "Fam107a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARAGPEYREWNSELIKPKKLLNPVKASRSHQELHRELLMNHKRGLGMDRKPELQRVLEHRRRNQLIKKKEEELEAKRMQCPFEQELLRRQQRLNQLENPPQREEDHAPEFIKVRENLRRITTLTSEERAL", "length": 131 }, "evidence": [ { "id": "A0ABI0P2G7", "url": "https://omabrowser.org/oma/group/A0ABI0P2G7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95990-1", "protein_name": "Actin-associated protein FAM107A", "gene_name": "FAM107A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYSEIQRERADIGGLMARPEYREWNPELIKPKKLLNPVKASRSHQELHRELLMNHRRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLRRQQRLNQLEKPPEKEEDHAPEFIKVRENLRRIATLTSEEREL", "length": 144 }, "evidence": [ { "id": "A0ABI0P2G7", "url": "https://omabrowser.org/oma/group/A0ABI0P2G7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q78TU8-1", "protein_name": "Actin-associated protein FAM107A", "gene_name": "Fam107a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYSEIQRERADIEGLMARPEYREWNSELIKPKKLLNPVKASRSHQELHRELLMNHKRGLGMDSKPELQRVLEHRRRNQLIKKKEEELEAKRMQCPFKQELLRRQQRLNQLENPPQRDEDHAPEFIKVRENLRRITTLTSEERAL", "length": 144 }, "evidence": [ { "id": "A0ABI0P2G7", "url": "https://omabrowser.org/oma/group/A0ABI0P2G7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2G7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2G7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2G7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2G7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2G7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2G7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2G7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 35, "end_pos": 37 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4M5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4M5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RNF24", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4M5", "locus": { "chromosome": "13", "start_pos": 51268037, "end_pos": 51156460, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007922", "url": "https://www.ensembl.org/id/ENSBTAG00000007922" } ] } } ], "crossref": [ { "id": "cd16675", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16675", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22763", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22763", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22763:SF190", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22763:SF190", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9ST17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9ST17-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPH4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4M5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4M5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4M5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGAAPAPPPLGPPLAGAVARRLPLPPQPRLVQPDARWLLPGADGPSTLAASASTTDSSMSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPLQGPLPGAENIV", "length": 207, "header": "tr|A0ABI0P4M5-1|A0ABI0P4M5_BOVIN Isoform 1 of RING finger protein 24 OS=Bos taurus OX=9913 GN=RNF24 PE=4 SV=1 CANONICAL=A0ABI0P4M5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9ST17-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4M5/entry#A0AAA9ST17-1", "sequence": { "sequence": "MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCALSNGWKFAKYVHCATCQFCSWPSCTVSRTVDPYRDPSPGQRTLYSSPQGSNCCRIWEEQSWEEHKWSLCWLLYLGHQLLLPLSHEELSGQLGWEPRLLGLVTTKVL", "length": 203, "header": "tr|A0AAA9ST17-1|A0ABI0P4M5_BOVIN Computationally mapped isoform of RING finger protein 24 OS=Bos taurus OX=9913 GN=RNF24 PE=4 SV=2 CANONICAL=A0ABI0P4M5-1" }, "locus": { "chromosome": "13", "start_pos": 51267033, "end_pos": 51228915, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123890.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123890.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088497.2", "url": "https://www.ensembl.org/id/ENSBTAP00000088497.2" } ] } }, { "isoform_ac": "A0ABI0NPH4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4M5/entry#A0ABI0NPH4-1", "sequence": { "sequence": "MEFSSSSMSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPLQGPLPGAENIV", "length": 155, "header": "tr|A0ABI0NPH4-1|A0ABI0P4M5_BOVIN Computationally mapped isoform of RING finger protein 24 OS=Bos taurus OX=9913 GN=RNF24 PE=4 SV=1 CANONICAL=A0ABI0P4M5-1" }, "locus": { "chromosome": "13", "start_pos": 51266846, "end_pos": 51156728, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148646.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148646.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107569.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107569.1" } ] } }, { "isoform_ac": "A0ABI0P4M5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4M5/entry#A0ABI0P4M5-1", "sequence": { "sequence": "MRGAAPAPPPLGPPLAGAVARRLPLPPQPRLVQPDARWLLPGADGPSTLAASASTTDSSMSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPLQGPLPGAENIV", "length": 207, "header": "tr|A0ABI0P4M5-1|A0ABI0P4M5_BOVIN Isoform 1 of RING finger protein 24 OS=Bos taurus OX=9913 GN=RNF24 PE=4 SV=1 CANONICAL=A0ABI0P4M5-1" }, "locus": { "chromosome": "13", "start_pos": 51266846, "end_pos": 51160948, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153127.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153127.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105730.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105730.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4M5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4M5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P4M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4M5" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 137, "end_pos": 178, "start_aa": "Cys", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 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zinc finger-containing protein 3 OS=Bos taurus OX=9913 GN=ZZZ3 PE=4 SV=1 CANONICAL=A0ABI0P3Q8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TDC4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q8/entry#A0AAA9TDC4-1", "sequence": { "sequence": "MIDLWLYSYQRLLQTIAVLEAQRSQAVQDLESLGRHQREALKNPIGFVEKLQKKADIGLPYPQRVVQLPEIVWDQYTNSLGNFEREFKNRKRHTRRVKLVFDKVGLPARPKSPLDPRKDGESLSYSMLPLSDGPEGSNSRPQMIRGRLCDDTKPETFNQLWTVEEQKKLEQLLLKYPPEEVESRRWQKIADELGNRTAKQVASRVQKYFIKLTKAGIPVPGRTPNLYIYSKKSSTSRRQHPLNKHLFKPSTFMTSHEPPVYMDEDDDRSCFHSHMNTAVEEASDEESIPVTYRNLPEYKELLQFKKLKKQKLQQIQAESGFVQHVGFKCDNCGIEPIQGVRWHCQDCPPEMSLDFCDSCSDCLHETDIHKEDHQLEPVYRSETFLDRDYCVSQGTSYNYLDPNYFPANR", "length": 409, "header": "tr|A0AAA9TDC4-1|A0ABI0P3Q8_BOVIN Computationally mapped isoform of ZZ-type zinc finger-containing protein 3 OS=Bos taurus OX=9913 GN=ZZZ3 PE=4 SV=1 CANONICAL=A0ABI0P3Q8-1" }, "locus": { "chromosome": "3", "start_pos": 67092875, "end_pos": 67025238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134659.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134659.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096121.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096121.1" } ] } }, { "isoform_ac": "A0ABI0P3Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q8/entry#A0ABI0P3Q8-1", "sequence": { "sequence": "MAASRSTRVTRSTVGLNGLDESFCGRTLRNRSIAHPEEISSHSQVRSRSPKKRPEPVQIQKGNNNGRTTDIKQQSARESWVSPRKRGLPSSEKDNIERQAVENCERRQTEPVSPVLKRIKRCLRSEAPNSSEEDSPIKSDKESVEQRSTVVDNDADFQGTKRACRCLILDDCEKREIKKVNVSEEGPLDSTVVEEITGYLAVNGVDDSDSAVINCDDCQPDGNTKQNSTGSYVLQEKSVAENGDSDTHASMFLDSRKEDGYINHNVPCTDSEVQVKLEDHKVVTACLPVERVNQLTTEPATGPFAEIHSSLRDSEEEVDVVGDSSASKEQCNESTNNALDTSLESMPVSGEPEPSSVLDCVSTQMMSLSEPQEHRYTLRTSPRRAAPTRGSPTKNNSPCRENGQFEENNLNPSETNATVSDNISESLTNPGEVSHSEKGICCDSENYGSEGLSKPSSEARLNAGHLPSAKESANPHITEEEDDDPDVYYFESDHVALKHNKDYQRLLQTIAVLEAQRSQAVQDLESLGRHQREALKNPIGFVEKLQKKADIGLPYPQRVVQLPEIVWDQYTNSLGNFEREFKNRKRHTRRVKLVFDKVGLPARPKSPLDPRKDGESLSYSMLPLSDGPEGSNSRPQMIRGRLCDDTKPETFNQLWTVEEQKKLEQLLLKYPPEEVESRRWQKIADELGNRTAKQVASRVQKYFIKLTKAGIPVPGRTPNLYIYSKKSSTSRRQHPLNKHLFKPSTFMTSHEPPVYMDEDDDRSCFHSHMNTAVEEASDEESIPVTYRNLPEYKELLQFKKLKKQKLQQIQAESGFVQHVGFKCDNCGIEPIQGVRWHCQDCPPEMSLDFCDSCSDCLHETDIHKEDHQLEPVYRSETFLDRDYCVSQGTSYNYLDPNYFPANR", "length": 903, "header": "tr|A0ABI0P3Q8-1|A0ABI0P3Q8_BOVIN Isoform 1 of ZZ-type zinc finger-containing protein 3 OS=Bos taurus OX=9913 GN=ZZZ3 PE=4 SV=1 CANONICAL=A0ABI0P3Q8-1" }, "locus": { "chromosome": "3", "start_pos": 67092875, "end_pos": 67030382, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143578.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143578.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105947.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105947.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q8" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q8" } ], "pmid": "" }, { "name": "regulation of cell division", "id": "GO:0051302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051302", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "ATAC complex", "id": "GO:0140672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140672", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q8" } ], "pmid": "" }, { "name": "SAGA-type complex", "id": "GO:0070461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070461", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 689, "end_pos": 691, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P3Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q8" }, { "id": "PS51294", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51294" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH myb-type", "eco_id": "ECO_0000259", "start_pos": 655, "end_pos": 707, "start_aa": "Trp", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P3Q8", "database": "UniProtKB", "url": 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P1G9-1", "uniprot_ac": "A0ABI0P1G9", "uniprot_id": "A0ABI0P1G9_BOVIN", "mass": { "chemical_mass": 101124.0, "monoisotopic_mass": 101124.0 }, "refseq": { "ac": "XP_010802412", "name": "rap guanine nucleotide exchange factor 5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802412" }, "gene_names": [ { "name": "RAPGEF5", "type": "recommended", "evidence": [ { "id": "A0ABI0P1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9" } ] }, { "name": "RAPGEF5", "type": "synonym", "evidence": [ { "id": "XP_010802412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802412" } ] } ], "protein_names": [ { "name": "Rap guanine nucleotide exchange factor 5", "type": "recommended", "evidence": [ { "id": "A0ABI0P1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9/entry#names_and_taxonomy" } ] }, { "name": "M-Ras-regulated Rap GEF", "type": "synonym", "evidence": [ { "id": "A0ABI0P1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9/entry#names_and_taxonomy" } ] }, { "name": "rap guanine nucleotide exchange factor 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_010802412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802412" } ] } ], "function": [ { "annotation": "Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9#function" }, { "database": "UniProtKB", "id": "ARBA00055877", "url": "https://www.uniprot.org/uniprotkb/ARBA00055877#function" }, { "database": "UniProtKB", "id": "A0AAA9TDZ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDZ4#function" }, { "database": "UniProtKB", "id": "A0ABI0NJP5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJP5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RAPGEF5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9", "locus": { 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"IPR000651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N3K6", "url": "https://www.orthodb.org/?gene=F1N3K6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00610", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00610", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00618", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00618", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010802412", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802412", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TDZ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TDZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJP5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJP5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNP1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNP1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1G9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1G9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3K6", "url": "https://www.uniprot.org/uniprotkb/F1N3K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3K6-1", "url": "https://www.uniprot.org/uniprotkb/F1N3K6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRMAVGSVKMQPPCESPALAAVAAVAAADGALRRSPSAREPEREQLPVPPRPRLRDLPALLRSGLTLRRKRSAAGGRTLSRRISNPYLEHTPSQIYGENSSCAGRALRNIIIVQAADLIKDRANLKGFYRRSCVGSELVDWLLEHCPFVQCRSMAIGVWQLLLDMGILSSVDQHLYFQDTYVFYQFSSEECSYLYCEFEREEEWQNGVRLLLQLVPLIPSRAGICELSHQKIEDSEESSDEILARLTSAVQRELAAVIALKARKSALAQDEENSDKHVTVTEAEAAADPQAGMMCKLQERDDIGRIELVQKLARESCQFLQTDKKEQEKSEHDDEVTTVEVKEQDQNVLVLKKVQSCGPAPQAGSAESDWRYVVVSGTPEKILEHLLNDLHLEEVQDKETETLLDDFLLTYTVFMTTDDLCQALLRHYSAKKYQGKEENSDVPCRKRKVLHLVSQWIALYKDWLHEDEHSKMFLKTIYRNVLDDVYEYPILEKELKEFQKILGMHRRHTVDEYSPQRKNKALFHQFSLKENWLQHRGTVTESEEIFCHVYITEHSYVSVKATVSSTAQEILRVVAEKIQHAEDDLALVAVTFSGEKHELQPNNLAISKSLDASGRIYVYRKDLADTLNPFAENEESQQRSIRILGMNTWDLALELMNFDWSLFSSIHEQELIYFTFSRQGSGEHTANLSLLLQRCNEVQLWVATEILLCSPLGKRVQLVKKFIKIAAHCKAQRNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNHKAYRDAFKKMKPPKIPFMPLLLKDVTFIHEGNKTFLDNLVNFEKLHMIADTVRTLRHCRTNQFGGDISPKEHPELKSYVHHLYVIDSQQALFELSHRIEPRV", "length": 883, "header": "tr|A0ABI0P1G9-1|A0ABI0P1G9_BOVIN Isoform 1 of Rap guanine nucleotide exchange factor 5 OS=Bos taurus OX=9913 GN=RAPGEF5 PE=4 SV=1 CANONICAL=A0ABI0P1G9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TDZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9/entry#A0AAA9TDZ4-1", "sequence": { "sequence": "MTKTLSRRISNPYLEHTPSQIYGENSSCAGRALRNIIIVQAADLIKDRANLKGFYRRSCVGSELVDWLLEHCPFVQCRSMAIGVWQLLLDMGILSSVDQHLYFQDTYVFYQFSSEECSYLYCEFEREEEWQNGVRLLLQLVPLIPSRAGICELSHQKIEDSEESSDEILARLTSAVQRELAAVIALKARKSALAQDEENSDKHVTVTEAEAAADPQAGMMCKLQERDDIGRIELVQKLARESCQFLQTDKKEQEKSEHQDDEVTTVEVKEQDQNVLVLKKVQSCGPAPQAGSAESDWRYVVVSGTPEKILEHLLNDLHLEEVQDKETETLLDDFLLTYTVFMTTDDLCQALLRHYSAKKYQGKEENSDVPCRKRKVLHLVSQWIALYKDWLHEDEHSKMFLKTIYRNVLDDVYEYPILEKELKEFQKILGMHRRHTVDEYSPQRKNKALFHQFSLKENWLQHRGTVTESEEIFCHVYITEHSYVSVKATVSSTAQEILRVVAEKIQHAEDDLALVAVTFSGEKHELQPNNLAISKSLDASGRIYVYRKDLADTLNPFAENEESQQRSIRILGMNTWDLALELMNFDWSLFSSIHEQELIYFTFSRQGSGEHTANLSLLLQRCNEVQLWVATEILLCSPLGKRVQLVKKFIKIAAHCKAQRNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNHKAYRDAFKKMKPPKIPFMPLLLKDVTFIHEGNKTFLDNLVNFEKLHMIADTVRTLRHCRTNQFGGDISPKEHPELKSYVHHLYVIDSQQALFELSHRIEPRV", "length": 810, "header": "tr|A0AAA9TDZ4-1|A0ABI0P1G9_BOVIN Computationally mapped isoform of Rap guanine nucleotide exchange factor 5 OS=Bos taurus OX=9913 GN=RAPGEF5 PE=4 SV=2 CANONICAL=A0ABI0P1G9-1" }, "locus": { "chromosome": "4", "start_pos": 31164959, "end_pos": 30912288, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092468.2", "url": "https://www.ensembl.org/id/ENSBTAT00000092468.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096357.2", "url": "https://www.ensembl.org/id/ENSBTAP00000096357.2" } ] } }, { "isoform_ac": "A0ABI0NJP5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9/entry#A0ABI0NJP5-1", "sequence": { "sequence": "MTLSRRISNPYLEHTPSQIYGENSSCAGRALRNIIIVQAADLIKDRANLKGFYRRSCVGSELVDWLLEHCPFVQCRSMAIGVWQLLLDMGILSSVDQHLYFQDTYVFYQFSSEECSYLYCEFEREEEWQNGVRLLLQLVPLIPSRAGICELSHQKIEDSEESSDEILARLTSAVQRELAAVIALKARKSALAQDEENSDKHVTVTEAEAAADPQAGMMCKLQERDDIGRIELVQKLARESCQFLQTDKKEQEKSEHQDDEVTTVEVKEQDQNVLVLKKVQSCGPAPQAGSAESDWRYVVVSGTPEKILEHLLNDLHLEEVQDKETETLLDDFLLTYTVFMTTDDLCQALLRHYSAKKYQGKEENSDVPCRKRKVLHLVSQWIALYKDWLHEDEHSKMFLKTIYRNVLDDVYEYPILEKELKEFQKILGMHRRHTVDEYSPQRKNKALFHQFSLKENWLQHRGTVTESEEIFCHVYITEHSYVSVKATVSSTAQEILRVVAEKIQHAEDDLALVAVTFSGEKHELQPNNLAISKSLDASGRIYVYRKDLADTLNPFAENEESQQRSIRILGMNTWDLALELMNFDWSLFSSIHEQELIYFTFSRQGSGEHTANLSLLLQRCNEVQLWVATEILLCSPLGKRVQLVKKFIKIAAHCKAQRNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNHKAYRDAFKKMKPPKIPFMPLLLKDVTFIHEGNKTFLDNLVNFEKLHMIADTVRTLRHCRTNQFGGDISPKEHPELKSYVHHLYVIDSQQALFELSHRIEPRV", "length": 808, "header": "tr|A0ABI0NJP5-1|A0ABI0P1G9_BOVIN Computationally mapped isoform of Rap guanine nucleotide exchange factor 5 OS=Bos taurus OX=9913 GN=RAPGEF5 PE=4 SV=1 CANONICAL=A0ABI0P1G9-1" }, "locus": { "chromosome": "4", "start_pos": 31126292, "end_pos": 30912288, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148087.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148087.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104724.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104724.1" } ] } }, { "isoform_ac": "A0ABI0NNP1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9/entry#A0ABI0NNP1-1", "sequence": { "sequence": "MRMAVGSVKMQPPCESPALAAVAAVAAADGALRRSPSAREPEREQLPVPPRPRLRDLPALLRSGLTLRRKRSAAGGRTLSRRISNPYLEHTPSQIYGENSSCAGRALRNIIIVQAADLIKDRANLKGFYRRSCVGSELVDWLLEHCPFVQCRSMAIGVWQLLLDMGILSSVDQHLYFQDTYVFYQFSSEECSYLYCEFEREEEWQNGVRLLLQLVPLIPSRAGICELSHQKIEDSEESSDEILARLTSAVQRELAAVIALKARKSALAQDEENSDKHVTVTEAEAAADPQAGMMCKLQERDDIGRIELVQKLARESCQFLQTDKKEQEKSEHQDDEVTTVEVKEQDQNVLVLKKVQSCGPAPQAGSAESDWRYVVVSGTPEKILEHLLNDLHLEEVQDKETETLLDDFLLTYTVFMTTDDLCQALLRHYSAKKYQGKEENSDVPCRKRKVLHLVSQWIALYKDWLHEDEHSKMFLKTIYRNVLDDVYEYPILEKELKEFQKILGMHRRHTVDEYSPQRKNKALFHQFSLKENWLQHRGTVTESEEIFCHVYITEHSYVSVKATVSSTAQEILRVVAEKIQHAEDDLALVAVTFSGEKHELQPNNLAISKSLDASGRIYVYRKDLADTLNPFAENEESQQRSIRILGMNTWDLALELMNFDWSLFSSIHEQELIYFTFSRQGSGEHTANLSLLLQRCNEVQLWVATEILLCSPLGKRVQLVKKFIKIAAHCKAQRNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNHKAYRDAFKKMKPPKIPFMPLLLKAPLLPLPGQTYLPCLILMPASACQPPPSGETPSSCADLDKSLRAGDKQDRPGRGEGRDRMSDKGNSKICRGPHIQ", "length": 880, "header": "tr|A0ABI0NNP1-1|A0ABI0P1G9_BOVIN Computationally mapped isoform of Rap guanine nucleotide exchange factor 5 OS=Bos taurus OX=9913 GN=RAPGEF5 PE=4 SV=1 CANONICAL=A0ABI0P1G9-1" }, "locus": { "chromosome": "4", "start_pos": 31143233, "end_pos": 30923144, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143055.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143055.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107346.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107346.1" } ] } }, { "isoform_ac": "A0ABI0P1G9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9/entry#A0ABI0P1G9-1", "sequence": { "sequence": "MRMAVGSVKMQPPCESPALAAVAAVAAADGALRRSPSAREPEREQLPVPPRPRLRDLPALLRSGLTLRRKRSAAGGRTLSRRISNPYLEHTPSQIYGENSSCAGRALRNIIIVQAADLIKDRANLKGFYRRSCVGSELVDWLLEHCPFVQCRSMAIGVWQLLLDMGILSSVDQHLYFQDTYVFYQFSSEECSYLYCEFEREEEWQNGVRLLLQLVPLIPSRAGICELSHQKIEDSEESSDEILARLTSAVQRELAAVIALKARKSALAQDEENSDKHVTVTEAEAAADPQAGMMCKLQERDDIGRIELVQKLARESCQFLQTDKKEQEKSEHDDEVTTVEVKEQDQNVLVLKKVQSCGPAPQAGSAESDWRYVVVSGTPEKILEHLLNDLHLEEVQDKETETLLDDFLLTYTVFMTTDDLCQALLRHYSAKKYQGKEENSDVPCRKRKVLHLVSQWIALYKDWLHEDEHSKMFLKTIYRNVLDDVYEYPILEKELKEFQKILGMHRRHTVDEYSPQRKNKALFHQFSLKENWLQHRGTVTESEEIFCHVYITEHSYVSVKATVSSTAQEILRVVAEKIQHAEDDLALVAVTFSGEKHELQPNNLAISKSLDASGRIYVYRKDLADTLNPFAENEESQQRSIRILGMNTWDLALELMNFDWSLFSSIHEQELIYFTFSRQGSGEHTANLSLLLQRCNEVQLWVATEILLCSPLGKRVQLVKKFIKIAAHCKAQRNLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPSLNHKAYRDAFKKMKPPKIPFMPLLLKDVTFIHEGNKTFLDNLVNFEKLHMIADTVRTLRHCRTNQFGGDISPKEHPELKSYVHHLYVIDSQQALFELSHRIEPRV", "length": 883, "header": "tr|A0ABI0P1G9-1|A0ABI0P1G9_BOVIN Isoform 1 of Rap guanine nucleotide exchange factor 5 OS=Bos taurus OX=9913 GN=RAPGEF5 PE=4 SV=1 CANONICAL=A0ABI0P1G9-1" }, "locus": { "chromosome": "4", "start_pos": 31143233, "end_pos": 30912288, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147002.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147002.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104507.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104507.1" } ] } }, { "isoform_ac": "F1N3K6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9/entry#F1N3K6-1", "sequence": { "sequence": "MRMAVGSVKMQPPCESPALAAVAAVAAADGALRRSPSAREPEREQLPVPPRPRLRDLPALLRSGLTLRRKRSAAGGRTLSRRISNPYLEHTPSQIYGENSSCAGRALRNIIIVQAADLIKDRANLKGFYRRSCVGSELVDWLLEHCPFVQCRSMAIGVWQLLLDMGILSSVDQHLYFQDTYVFYQFSSEECSYLYCEFEREEEWQNGVRLLLQLVPLIPSRAGICELSHQKIEDSEESSDEILARLTSAVQRELAAVIALKARKSALAQDEENSDKHVTVTEAEAAADPQAGMMCKLQERDDIGRIELVQKLARESCQFLQTDKKEQEKSEHQDDEVTTVEVKEQDQNVLVLKKVQSCGPAPQAGSAESDWSVLADCRAPSSQMDSVPSKRTEVARSLSI", "length": 400, "header": "tr|F1N3K6-1|A0ABI0P1G9_BOVIN Computationally mapped isoform of Rap guanine nucleotide exchange factor 5 OS=Bos taurus OX=9913 GN=RAPGEF5 PE=4 SV=3 CANONICAL=A0ABI0P1G9-1" }, "locus": { "chromosome": "4", "start_pos": 31143233, "end_pos": 30980172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000033832.5", "url": "https://www.ensembl.org/id/ENSBTAT00000033832.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000033741.5", "url": "https://www.ensembl.org/id/ENSBTAP00000033741.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9" } ], "pmid": "" }, { "name": "Rap protein signal transduction", "id": "GO:0032486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032486", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 687, "end_pos": 689, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9" }, { "id": "PS50186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DEP", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 188, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9" }, { "id": "PS50212", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50212" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-terminal Ras-GEF", "eco_id": "ECO_0000259", "start_pos": 370, "end_pos": 503, "start_aa": "Trp", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G9" }, { "id": "PS50009", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50009" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-GEF", "eco_id": "ECO_0000259", "start_pos": 647, "end_pos": 882, "start_aa": "Asn", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 687, "end_pos": 689 }, { "start_pos": 813, "end_pos": 815 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"categories": [ "Protein" ] }, { "id": "F1MLT6-1", "url": "https://www.uniprot.org/uniprotkb/F1MLT6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEPQEVSSRKDGRAGDIVVEKFLVDSMKPASHVQLACSGQSCAFPLDGNELCIWDTEEPPHQLMILKGHRQPITAVTFGSRESPLLVCSASLDCVLVWSLDECRQEELQGRLPRGTVLGTLLGRVLCLRLSPDDRVVAVCAGSRVLMLDLESRSPLAELDGHHGPVTAAEFCAWQTHILISASEDRSFKVWDHRMGSLIYSSSVLTAAPLLSLLVDPRSQQLVAGCTDGQLWIFSLVEGHHYRCVTHVDLRKKRESFSTRRAESKPEGGQPPSTKAPETGEETEVALPVLSLAACGCAFLSETARCLWIGSSTGLLIFNLSSFELEAVLHYKDFQSLSIQVAGSCAVASRTGGGEALCLLTSMFGNETALVEADPAALLRSQQRPHPGPDLSVLPSSCVLPTSPLYLGLKEKRTKQATQKQSAARSIVKDHPLVFHSKIRSSGYTAAPCATMFSPKTDFKNDGKRASKCKNNYSKECPVESPAPSKLSRQLAVACGQAALLCMQYSGDGQQLACGLANHLSLVCNADLTGKPAVLSGHDGAVSSVCWSHDGRWVLSASQDGTLRVWSVRSRKPALRLGKDTFPTPVQSAQFYYIDAFILSSSGPEVQLLKHHIDTSKDDLRRYRQKSWCTPVCRLLTTDATEITSLSAVNDFHSYIVLAAGRNRTLEVFDLNVGCSAAVITGAHSRPVHQICQNKGSSFATQQSQAYNLFATAATGDGVKLWDLRTLRCERRFEGHPSRCYPCGIAFSPCGRFVACGAEDRHAYVYETSSSTFSRRLTGHTSTVTAVAFSPVAAQLLQQSAASAPYRARGVAPLCHSCTITAAAPCQRMLKLPHSC", "length": 837, "header": "tr|A0ABI0P2F5-1|A0ABI0P2F5_BOVIN Isoform 1 of WD repeat domain 27 OS=Bos taurus OX=9913 GN=WDR27 PE=4 SV=1 CANONICAL=A0ABI0P2F5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TQ56-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2F5/entry#A0AAA9TQ56-1", "sequence": { "sequence": "MEEPQEVSSRKDGRAGDIVVEKFLVDSMKPASHVQLACSGQSCAFPLDGNELCIWDTEEPPHQLMILKGHRQPITAVTFGSRESPLLVCSASLDCVLVWSLDECRQEELQGRLPRGTVLGTLLGRVLCLRLSPDDRVVAVCAGSRVLMLDLESRSPLAELDGHHGPVTAAEFCAWQTHILISASEDRSFKVWDHRMGSLIYSSSVLTAAPLLSLLVDPRSQQLVAGCTDGQLWIFSLVEGHHYRCVTHVDLRKKRESFSTRRAESKPEGGQPPSTKAPETGEETEVALPVLSLAACGCAFLSETARCLWIGSSTGLLIFNLSSFELEAVLHYKDFQSLSIQVAGSCAVASRTGGGEALCLLTSMFGNETALVEADPAALLRSQQRPHPGPDLSVLPSSCVLPTSPLYLGLKEKRTKQATQKQSAARSIVKDHPLVFHSKIRSSGYTAAPCATMFSPKTDFKNDGKRASKCKNNYSKECPVESPAPSKLSRQLAVACGQAALLCMQYSGDGQQLACGLANHLSLVCNADLTGKPAVLSGHDGAVSSVCWSHDGRWVLSASQDGTLRVWSVRSRKPALRLGKDTFPTPVQSAQFYYIDAFILSSSGPEVQLLKHHIDTSKDDLRRYRQKSWCTPVCRLLTTDATEITSLSAVNDFHSYIVLAAGRNRTLEVFDLNVGCSAAVITGAHSRPVHQICQNKGSSFATQQSQAYNLFATAATGDGVKLWDLRTLRCERRFEGHPSRCYPCGIAFSPCGRFVACGAEDRHVHRC", "length": 767, "header": "tr|A0AAA9TQ56-1|A0ABI0P2F5_BOVIN Computationally mapped isoform of WD repeat domain 27 OS=Bos taurus OX=9913 GN=WDR27 PE=4 SV=1 CANONICAL=A0ABI0P2F5-1" }, "locus": { "chromosome": "9", "start_pos": 103486013, "end_pos": 103430067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108341.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108341.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100708.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100708.1" } ] } }, { "isoform_ac": "A0ABI0P2F5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2F5/entry#A0ABI0P2F5-1", "sequence": { "sequence": "MEEPQEVSSRKDGRAGDIVVEKFLVDSMKPASHVQLACSGQSCAFPLDGNELCIWDTEEPPHQLMILKGHRQPITAVTFGSRESPLLVCSASLDCVLVWSLDECRQEELQGRLPRGTVLGTLLGRVLCLRLSPDDRVVAVCAGSRVLMLDLESRSPLAELDGHHGPVTAAEFCAWQTHILISASEDRSFKVWDHRMGSLIYSSSVLTAAPLLSLLVDPRSQQLVAGCTDGQLWIFSLVEGHHYRCVTHVDLRKKRESFSTRRAESKPEGGQPPSTKAPETGEETEVALPVLSLAACGCAFLSETARCLWIGSSTGLLIFNLSSFELEAVLHYKDFQSLSIQVAGSCAVASRTGGGEALCLLTSMFGNETALVEADPAALLRSQQRPHPGPDLSVLPSSCVLPTSPLYLGLKEKRTKQATQKQSAARSIVKDHPLVFHSKIRSSGYTAAPCATMFSPKTDFKNDGKRASKCKNNYSKECPVESPAPSKLSRQLAVACGQAALLCMQYSGDGQQLACGLANHLSLVCNADLTGKPAVLSGHDGAVSSVCWSHDGRWVLSASQDGTLRVWSVRSRKPALRLGKDTFPTPVQSAQFYYIDAFILSSSGPEVQLLKHHIDTSKDDLRRYRQKSWCTPVCRLLTTDATEITSLSAVNDFHSYIVLAAGRNRTLEVFDLNVGCSAAVITGAHSRPVHQICQNKGSSFATQQSQAYNLFATAATGDGVKLWDLRTLRCERRFEGHPSRCYPCGIAFSPCGRFVACGAEDRHAYVYETSSSTFSRRLTGHTSTVTAVAFSPVAAQLLQQSAASAPYRARGVAPLCHSCTITAAAPCQRMLKLPHSC", "length": 837, "header": "tr|A0ABI0P2F5-1|A0ABI0P2F5_BOVIN Isoform 1 of WD repeat domain 27 OS=Bos taurus OX=9913 GN=WDR27 PE=4 SV=1 CANONICAL=A0ABI0P2F5-1" }, "locus": { "chromosome": "9", "start_pos": 103486013, "end_pos": 103381591, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142112.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142112.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104841.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104841.1" } ] } }, { "isoform_ac": "F1MLT6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2F5/entry#F1MLT6-1", "sequence": { "sequence": "MEEPQEVSSRKDGRAGDIVVEKFLVDSMKPASHVQLACSGQSCAFPLDGNELCIWDTEEPPHQLMILKGHRQPITAVTFGSRESPLLVCSASLDCVLVWSLDECRQEELQAAPLLSLLVDPRSQQLVAGCTDGQLWIFSLVEGHHYRCVTHVDLRKKRESFSTRRAESKPGTWPEGGQPPSTKAPETGEETEVALPVLSLAACGCAFLSETARCLWIGSSTGLLIFNLSSFELEAVLHYKDFQSLSIQVAGSCAVASRTGGGEALCLLTSMFGNETALVEADPAALLRSQQRPHPGPDLSVLPSSCVLPTSPLYLGLKEKRTKQATQKQSAARSIVKDHPLVFHSKIRSSGYTAAPCATMFSPKTDFKNDGKRASKCKNNYRLKECPVESPAPSKLSRQLAVACGQAALLCMQYSGDGQQLACGLANHLSLVCNADLTGKPAVLSGHDGAVSSVCWSHDGRWVLSASQDGTLRVWSVRSRKPALRLGKDTFPTPVQSAQFYYIDAFILSSSGPEVQLLKHHIDTSKDLTKYRQKSWCTPVCRLLTTDATEITSLSAVNDFHSYIVLAAGRNRTLEVFDLNVGCSAAVITGAHSRPVHQICQNKGSSFATQQSQAYNLFATAATGDGVKLWDLRTLRCERRFEGHPSRCYPCGIAFSPCGRFVACGAEDRHAYVYETSSSTFSRRLTGHTSTVTAVAFSPVAAQLVTATLDGKLQLFQAE", "length": 719, "header": "tr|F1MLT6-1|A0ABI0P2F5_BOVIN Computationally mapped isoform of WD repeat domain 27 OS=Bos taurus OX=9913 GN=WDR27 PE=4 SV=4 CANONICAL=A0ABI0P2F5-1" }, "locus": { "chromosome": "9", "start_pos": 103486013, "end_pos": 103347516, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061523.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061523.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053233.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053233.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 664, "end_pos": 666, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 320, "end_pos": 322 }, { "start_pos": 367, "end_pos": 369 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 664, "end_pos": 666 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P4H8-1", "uniprot_ac": "A0ABI0P4H8", "uniprot_id": "A0ABI0P4H8_BOVIN", "mass": { "chemical_mass": 37248.0, "monoisotopic_mass": 37248.0 }, "refseq": { "ac": "XP_015331114", "name": "radial spoke head 14 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015331114" }, "gene_names": [ { "name": "GNAZ", "type": "recommended", "evidence": [ { "id": "A0ABI0P4H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ] }, { "name": "RSPH14", "type": "recommended", "evidence": [ { "id": "A0ABI0P4H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ] }, { "name": "GNAZ", "type": "synonym", "evidence": [ { "id": "A0ABI0P4H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ] }, { "name": "RSPH14", "type": "synonym", "evidence": [ { "id": "XP_015331114", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015331114" } ] }, { "name": "RTDR1", "type": "synonym", "evidence": [ { "id": "XP_015331114", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015331114" } ] } ], "protein_names": [ { "name": "Radial spoke head 14 homolog", "type": "synonym", "evidence": [ { "id": "A0ABI0P4H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8/entry#names_and_taxonomy" } ] }, { "name": "radial spoke head 14 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015331114", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015331114" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RSPH14", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8", "locus": { "chromosome": "17", "start_pos": 71864794, "end_pos": 71816210, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000036113", "url": "https://www.ensembl.org/id/ENSBTAG00000036113" } ] } } ], "crossref": [ { "id": "ENSBTAG00000036113", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000036113", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000047664", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047664", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "616270", "url": "https://www.ncbi.nlm.nih.gov/gene/616270", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "9FQR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9FQR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001019", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001019", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:112442078", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112442078", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ANSHWFK", "url": "https://omabrowser.org/oma/group/ANSHWFK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "VWQHDVI", "url": "https://omabrowser.org/oma/group/VWQHDVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MM27", "url": "https://www.orthodb.org/?gene=A0A3Q1MM27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10218", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10218", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10218:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10218:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15599", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15599", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15599:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15599:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00009fqr", "url": "https://www.rcsb.org/structure/pdb_00009fqr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9FQR", "url": "https://www.rcsb.org/structure/9FQR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00503", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00503", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00514", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00514", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12717", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12717", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-418597", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015331114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015331114", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MM27", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MM27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MM27-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MM27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4H8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N594", "url": "https://www.uniprot.org/uniprotkb/F1N594", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N594-1", "url": "https://www.uniprot.org/uniprotkb/F1N594-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0K2", "url": "https://www.uniprot.org/uniprotkb/G3N0K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0K2-1", "url": "https://www.uniprot.org/uniprotkb/G3N0K2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADAKISMYLPPNVNPTQAAIAYGCRALPKLNEELQSDDLLTRQKALMALCDLMHDPEHVYTAISIGCLESLKALLKDTNDLVRIKTTEVLCIMATHNVGREGFLEHNVIQALSFLMSDAQPACRENLYTAFKHLAQLPAGALGIVNSGLIPSLVWKLQREEEEIQVLLLDTLAACLTEDATEALASRAVPFLKEKLLSTNCNIRSKAARTLIAVSVPPEGKIQVWQHDVIPILVHLLKDRDEEVQANAAGALMNATVTTEGKYAALDAEATRPLLQLLTSSLSKARLNAIKALTMLAEAPEGRKLLQPHVATFRALEEDFSPAVQRAAQIAIRVIEWKP", "length": 340, "header": "tr|A0ABI0P4H8-1|A0ABI0P4H8_BOVIN Isoform 1 of Radial spoke head 14 homolog OS=Bos taurus OX=9913 GN=RSPH14 PE=4 SV=1 CANONICAL=A0ABI0P4H8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MM27-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8/entry#A0A3Q1MM27-1", "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTVVKQMKILHSGGFNLEACREYKPLIVYNAIDSLTRIVRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYVPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTDGMIRSRVVSRASLFIVRAQNSPSSNDSALGWPCLQDTHLIHLKTQGRSPPAGVPLEARAGWPRACASSTPSATTTGSSARPSSSS", "length": 327, "header": "tr|A0A3Q1MM27-1|A0ABI0P4H8_BOVIN Computationally mapped isoform of Radial spoke head 14 homolog OS=Bos taurus OX=9913 GN=RSPH14 PE=4 SV=2 CANONICAL=A0ABI0P4H8-1" }, "locus": { "chromosome": "17", "start_pos": 71844565, "end_pos": 71828970, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074311.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074311.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072143.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072143.2" } ] } }, { "isoform_ac": "A0ABI0P4H8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8/entry#A0ABI0P4H8-1", "sequence": { "sequence": "MADAKISMYLPPNVNPTQAAIAYGCRALPKLNEELQSDDLLTRQKALMALCDLMHDPEHVYTAISIGCLESLKALLKDTNDLVRIKTTEVLCIMATHNVGREGFLEHNVIQALSFLMSDAQPACRENLYTAFKHLAQLPAGALGIVNSGLIPSLVWKLQREEEEIQVLLLDTLAACLTEDATEALASRAVPFLKEKLLSTNCNIRSKAARTLIAVSVPPEGKIQVWQHDVIPILVHLLKDRDEEVQANAAGALMNATVTTEGKYAALDAEATRPLLQLLTSSLSKARLNAIKALTMLAEAPEGRKLLQPHVATFRALEEDFSPAVQRAAQIAIRVIEWKP", "length": 340, "header": "tr|A0ABI0P4H8-1|A0ABI0P4H8_BOVIN Isoform 1 of Radial spoke head 14 homolog OS=Bos taurus OX=9913 GN=RSPH14 PE=4 SV=1 CANONICAL=A0ABI0P4H8-1" }, "locus": { "chromosome": "17", "start_pos": 71864730, "end_pos": 71817575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153190.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153190.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106226.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106226.1" } ] } }, { "isoform_ac": "F1N594-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8/entry#F1N594-1", "sequence": { "sequence": "MADAKISMYLPPNVNPTQAAIAYGCRALPKLNEELQSDDLLTRQKALMALCDLMHDPEHVYTAISIGCLESLKALLKDTNDLVRIKTTEVLCIMATHNVGREGFLEHNVIQALSFLMSDAQPACRENLYTAFKHLAQLPAELQVVAAELHAEDDRGDALEAVDPLFALRPLAAHVHHLEGALGIVNSGLIPSLVWKLQREEEEIQVLLLDTLAACLTEDATEALASRAVPFLKEKLLSTNCNIRSKAARTLIAVSVPPEGKIQVWQHDVIPILVHLLKDRDEEVQANAAGALMNATVTTEGKYAALDAEATRPLLQLLTSSLSKARLNAIKALTMLAEAPEGRKLLQPHVATFRALEEDFSPAVQRAAQIAIRVIEWKP", "length": 379, "header": "tr|F1N594-1|A0ABI0P4H8_BOVIN Computationally mapped isoform of Radial spoke head 14 homolog OS=Bos taurus OX=9913 GN=RSPH14 PE=4 SV=2 CANONICAL=A0ABI0P4H8-1" }, "locus": { "chromosome": "17", "start_pos": 71864730, "end_pos": 71817575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053430.4", "url": "https://www.ensembl.org/id/ENSBTAT00000053430.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052597.2", "url": "https://www.ensembl.org/id/ENSBTAP00000052597.2" } ] } }, { "isoform_ac": "G3N0K2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8/entry#G3N0K2-1", "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTVVKQMKILHSGGFNLEACREYKPLIVYNAIDSLTRIVRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYVPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFVSTSLILFLNKKDLLAQKIRRIPLTVCFPEYSGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTGNIQFVFDAVTDVIIQNNLKYIGLC", "length": 355, "header": "tr|G3N0K2-1|A0ABI0P4H8_BOVIN Computationally mapped isoform of Radial spoke head 14 homolog OS=Bos taurus OX=9913 GN=RSPH14 PE=4 SV=3 CANONICAL=A0ABI0P4H8-1" }, "locus": { "chromosome": "17", "start_pos": 71844565, "end_pos": 71828710, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063773.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063773.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055365.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055365.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Structural diversity of axonemes across mammalian motile cilia.", "journal": "Nature", "date": "2025", "authors": "Leung Miguel Ricardo, Sun Chen, Zeng Jianwei, Anderson Jacob R, Niu Qingwei, Huang Wei, Noteborn Willem E M, Brown Alan, Zeev-Ben-Mordehai Tzviya, Zhang Rui", "evidence": [ { "database": "UniProtKB", "id": "F1N594", "url": "https://www.uniprot.org/uniprotkb/F1N594" } ], "reference": [ { "type": "PubMed", "id": "39743588", "url": "https://glygen.org/publication/PubMed/39743588" } ] } ], "pathway": [ { "id": "bta:112442078", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112442078", "resource": "KEGG Pathway" }, { "id": "R-BTA-418597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418597", "resource": "Reactome", "description": "G alpha (z) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0V7-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "Rsph14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRKRSWFTSCSKRLMEALQRSSSCSMSPTERSSMRGGSESGNCALQASAKPTESTMARPAHLRRGAARRSPAQRRRGVLTVPGPGRPAPPMIPRLRRRTMPAPRGRSFYKVSSSKPVGRRGKMAHARISMYMPPDIDPTKAAIAYGCRALRKLNEELQSEDLLTRQKAVMALCDLMHDPEYVYEAINIGCLESLKALLKDDDNLVRIKTTEVLYIMATHNVGRVGFLKHDIILALSRLLSDHQTLCRENLHQAYKHLAQLPEGAQGIVTSGLISFLVRKLQKEELHIQEIILDTLALCLQEDATEALNSQAVPCFKEKLFSGNPQIRSKAARALIAISIPLDGKRQVWQNEVIPILVDLLSDTDEEVKANAAGALMHATVTTEGKYAALDANAIDPLLELLCSIPTTKVCLNATKALTMLAEAPEGRKLLLPRVPTFRYLLTHKNEAIRRAAEVAIKVIEWKP", "length": 463 }, "evidence": [ { "id": "A0ABI0P4H8", "url": "https://omabrowser.org/oma/group/A0ABI0P4H8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1P3V2-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "rsph14", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASPQTTEQPPPHIDPTQAPIAFGNLALPKLLVELQDDDLFTRQKALTALCDLLHDPERAYEAIFSECLEILKVLLQDEDSLIRVKTTEVLYVLASHSMGRDAFLNFDIVGPLANLLDDPEIACRKNVHRALNRIAEFPLGAVFMVNKGLVPRLVPKISIEEENIRALVLSTLSCCLSVNALPALESDVIQVLRDQLSHSSPIIRKEAASALMAISVPTVGKIKVCEENLLPILVKLLSDDDQEVVANAAGTIMNTAVITKGKSEALEADALAPLLQLVLSENTAVCANALRALTVLAEVPRARAHLRQHVPLLKTRLTDPNYLIQEAASTTIEVISWQP", "length": 340 }, "evidence": [ { "id": "A0ABI0P4H8", "url": "https://omabrowser.org/oma/group/A0ABI0P4H8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V1ADH4-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "RSPH14", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASTLISAKLPPDVDPTKAPIAFGRRALPKLSREIQSPELLTQQRALMALCDLVHDPENVYQAVQIGFLENLKTLLLHHDSTVRQKTTEILYIMAMHNVGRQGLIQNAVIPVLTELLDDPEDICRKNTHQVLDMMAKLPEGAVDILHAGLIPLLVVRLKTESDEIQELILGTLSNCLRMEASEALATDAITILKEKLTHPSATIRNKAAQVILEIGTHPEGKSTVCEEVIPLLVSLLEDTDPEVQASAAGALMFATIKPKGRCLALRAEAIPRLLKLVAVENSKARLSAIKTLTMLAEVAEGRRKLLERTDIFQQCLRDPSEAVKRAAEIAIRVIRWKPF", "length": 340 }, "evidence": [ { "id": "A0ABI0P4H8", "url": "https://omabrowser.org/oma/group/A0ABI0P4H8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1NZY0-1", "protein_name": "Guanine nucleotide-binding protein G(z) subunit alpha", "gene_name": "GNAZ", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALATLKIEFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMKRLWADPGVQECFCRSNEYHLEDNAAYYLNDLERIAALDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "length": 355 }, "evidence": [ { "id": "A0ABI0P4H8", "url": "https://omabrowser.org/oma/group/A0ABI0P4H8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RLS7-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "RSPH14", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADARISMYLPPDINPTQAAIAYGCRALPKLNEELQSEDLVTRQKALMALCGLMHDPEHVYMAIHIGCLENLKALLKDTNDMVRIKTTEVLYIMATHNVGRVGFLEHDVIRALSFLLNDPQSLCRENLHLAFKHLAQLPTGAQGIVSSGLIPSLVWKLQREEEGVQELLLDTLAACLMEDATEALASRAVPFLKEKLLSANSNIRSKAAGTLIAISIPLEGKNQVWKHDVIPILVHLLRDKVAEVQANVAGALMNATVTTEGKYAALNAEAIHPLLQLLCSSLSKARLNAIKALTMLAEAPEGRKLLQAHVPTFRALEKDTSAAVKQAAQIAIKVIEWKP", "length": 340 }, "evidence": [ { "id": "A0ABI0P4H8", "url": "https://omabrowser.org/oma/group/A0ABI0P4H8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RLT6-1", "protein_name": "Guanine nucleotide-binding protein G(z) subunit alpha", "gene_name": "GNAZ", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYVPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFVSTSLILFLNKKDLLAQKIRRIPLTVCFPEYGGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "length": 355 }, "evidence": [ { "id": "A0ABI0P4H8", "url": "https://omabrowser.org/oma/group/A0ABI0P4H8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HMY6-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "Rsph14", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAHARISMYMPPDIDPTKAAIAYGCRALPKLNEELQSEVLLTRQKALVALCDLMHDPEHVYEAIHIGCLESLKVLLKDEDNLVRIKTTEVLHIMATHNIGRTGLLEKGVILALALLLSDHQKVCRENLHQAYKHVAQTPEGARGITSSGLIPWLVNKLNAEEEHIQEIILDTLAPCLQEDATQALESQAVPYFKKKLLNDNPRIRSKAARALIAISIPLEGKNQVWQNGVIPILVDLLSDVDEEVQANAAGALMHATVTTEGKYAALDASAINPLLELLCSSPIKVCLNAAKALTMLAEAPEGRKLLSSHVSTFRVLLMHENEAIRRAAQVAIKVIEWKP", "length": 340 }, "evidence": [ { "id": "A0ABI0P4H8", "url": "https://omabrowser.org/oma/group/A0ABI0P4H8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HMY7-1", "protein_name": "Guanine nucleotide-binding protein G(z) subunit alpha", "gene_name": "Gnaz", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLDACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "length": 355 }, "evidence": [ { "id": "A0ABI0P4H8", "url": "https://omabrowser.org/oma/group/A0ABI0P4H8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O70443-1", "protein_name": "Guanine nucleotide-binding protein G(z) subunit alpha", "gene_name": "Gnaz", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLDACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "length": 355 }, "evidence": [ { "id": "A0ABI0P4H8", "url": "https://omabrowser.org/oma/group/A0ABI0P4H8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P19086-1", "protein_name": "Guanine nucleotide-binding protein G(z) subunit alpha", "gene_name": "GNAZ", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "length": 355 }, "evidence": [ { "id": "A0ABI0P4H8", "url": "https://omabrowser.org/oma/group/A0ABI0P4H8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P19627-1", "protein_name": "Guanine nucleotide-binding protein G(z) subunit alpha", "gene_name": "Gnaz", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLSEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "length": 355 }, "evidence": [ { "id": "A0ABI0P4H8", "url": "https://omabrowser.org/oma/group/A0ABI0P4H8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P34042-1", "protein_name": "Guanine nucleotide-binding protein alpha-4 subunit", "gene_name": "gpaD", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRFKCFGSEETEQSSKIDKSIETDRRKLRKDVKLLLLGPGESGKSTIFKQMKIIQEDGGYSVEELLEYRAFVYSNCISQMEALLTASAKLNIELEVENKQRAANVLRRTIGNEPWLLLAADIKHLWEDKGIKETYAQKDKHFQLNDSAAYFFDNIDRYMREDFVPNEQDVLRCRVRTTGIQESEFTFDKIRLKIVDVGGQRSQRRKWIHCFDCVTAVIFVAAMSDYDQVLREDESVNRTRESLALFKEIVNCDYFKETPIVLFLNKKDLFKEKLKRVPLQSCFSDYTGPNKYKDAAMFIQSQYLAQGPSPRTIYTHATCAVDTENIKFVFRAVRQTILSQALEHF", "length": 345 }, "evidence": [ { "id": "A0ABI0P4H8", "url": "https://omabrowser.org/oma/group/A0ABI0P4H8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9D3W1-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "Rsph14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAHARISMYMPPDIDPTKAAIAYGCRALSKLNEELQSRDLLTRQKALVALCDLMHDPEYVYEAINIGCLESLKTLLQDDDNLVRIKTTEVLYIMATHYVGRVGFLKHDIIQALSLLLSDHQTLCRENLHQAYKHLAQLPKGAQGIVQSGLIPSLVRKLQKEEDHIQEIILDTLALCLQEDATEALESQAVPCLKEKLLSQNSEIRSKAARALIAISIPLDGKNQVWKNKVIPILVTLLSDTDEEVKANAAGALMHATVTTEGKYAALDANAIEPLLELLSTNPKTKLCLNATKALTMLAEAPEGRKLLLSHVPIFRYLLAHKNEAIQRAAEVAIKVIEWKP", "length": 341 }, "evidence": [ { "id": "A0ABI0P4H8", "url": "https://omabrowser.org/oma/group/A0ABI0P4H8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHP6-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "RSPH14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAHSQNSLELPININATQITTAYGHRALPKLKEELQSEDLQTRQKALMALCDLMHDPECIYKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHSVGRYAFLEHDIVLALSFLLNDPSPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEVEEEEFQEFILDTLVLCLQEDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISREGKKQVCHFDVIPILVHLLKDPVEHVKSNAAGALMFATVITEGKYAALEAQAIGLLLELLHSPMTIARLNATKALTMLAEAPEGRKALQTHVPTFRAMEVETYEKPQVAEALQRAARIAISVIEFKP", "length": 348 }, "evidence": [ { "id": "A0ABI0P4H8", "url": "https://omabrowser.org/oma/group/A0ABI0P4H8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "radial spoke", "id": "GO:0001534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001534", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": 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"https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ], "pmid": "" }, { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ], "pmid": "" }, { "name": "G-protein beta/gamma-subunit complex binding", "id": "GO:0031683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031683", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ], "pmid": "" }, { "name": "adenylate cyclase inhibitor activity", "id": "GO:0010855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010855", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ], "pmid": "" }, { "name": "negative regulation of insulin secretion", "id": "GO:0046676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046676", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P4H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H8" }, { "id": "PF12717", "database": "Pfam", "url": 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0ABI0P290-1", "uniprot_ac": "A0ABI0P290", "uniprot_id": "A0ABI0P290_BOVIN", "mass": { "chemical_mass": 35712.0, "monoisotopic_mass": 35712.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC74B", "type": "recommended", "evidence": [ { "id": "A0ABI0P290", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P290" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 74B", "type": "recommended", "evidence": [ { "id": "A0ABI0P290", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P290/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P290", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P290" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC74B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P290", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000031018", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000031018", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR029422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14882", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14882", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14882:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14882:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14917", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14917", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0P290", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P290", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P290-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P290-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RWR7", "url": "https://www.uniprot.org/uniprotkb/F6RWR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RWR7-1", "url": "https://www.uniprot.org/uniprotkb/F6RWR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSATGVAAGQRPRSSGILSSRGTSRLRQRLPAVPQPGQHGASLGLNEAQKRVLDLEKSVQFLQQQHSETLVKLHEEIEHLKRENKDLHYKLIMNQKSHKKGKAEAHRYLVQTGSQGKARPQPGSSKKQDWKAEVPQKPDLEEETSVATLLHGGRVDKALGVQGLVKDEEADSANAVPPWAVGSQHKGRQVPEAPPSVGLPLHLRKPATLQQCEVVIRQLWNANLLQAQELQHLKSLLEGSQRPRAGPEEAGPSSPRDQEALHLGATQLPKVTAKGISKKCLILSRAPVAEHAILPALKQSLKTSFAERQRRLQAVQGRRLHRSVL", "length": 325, "header": "tr|A0ABI0P290-1|A0ABI0P290_BOVIN Isoform 1 of Coiled-coil domain containing 74B OS=Bos taurus OX=9913 GN=CCDC74B PE=4 SV=1 CANONICAL=A0ABI0P290-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P290-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P290/entry#A0ABI0P290-1", "sequence": { "sequence": "MSATGVAAGQRPRSSGILSSRGTSRLRQRLPAVPQPGQHGASLGLNEAQKRVLDLEKSVQFLQQQHSETLVKLHEEIEHLKRENKDLHYKLIMNQKSHKKGKAEAHRYLVQTGSQGKARPQPGSSKKQDWKAEVPQKPDLEEETSVATLLHGGRVDKALGVQGLVKDEEADSANAVPPWAVGSQHKGRQVPEAPPSVGLPLHLRKPATLQQCEVVIRQLWNANLLQAQELQHLKSLLEGSQRPRAGPEEAGPSSPRDQEALHLGATQLPKVTAKGISKKCLILSRAPVAEHAILPALKQSLKTSFAERQRRLQAVQGRRLHRSVL", "length": 325, "header": "tr|A0ABI0P290-1|A0ABI0P290_BOVIN Isoform 1 of Coiled-coil domain containing 74B OS=Bos taurus OX=9913 GN=CCDC74B PE=4 SV=1 CANONICAL=A0ABI0P290-1" }, "locus": { "chromosome": "17", "start_pos": 72430251, "end_pos": 72425885, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139370.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139370.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104641.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104641.1" } ] } }, { "isoform_ac": "F6RWR7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P290/entry#F6RWR7-1", "sequence": { "sequence": "MWRGHRNGRDGSVALPPWADPACPTGSTSSSSLQSNKSVSNTTVSAGSQGKARPQPGSSKKQDWKAEVPQKPDLEEETSVATLLHGGRVDKALGVQGLVKDEEADSANAVPPWAVGSQHKGRQVPEAPPSVGLPLHLRKPATLQQCEVVIRQLWNANLLQAQELQHLKSLLEGSQRPRAGPEEAGPSSPRDQEALHLGATQLPKVTAKGISKKCLILSRAPVAEHAILPALKQSLKTSFAERQRRLQAVQGRRLHRSVL", "length": 259, "header": "tr|F6RWR7-1|A0ABI0P290_BOVIN Computationally mapped isoform of Coiled-coil domain containing 74B OS=Bos taurus OX=9913 GN=CCDC74B PE=4 SV=4 CANONICAL=A0ABI0P290-1" }, "locus": { "chromosome": "17", "start_pos": 72430251, "end_pos": 72427345, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043907.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043907.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041443.5", "url": "https://www.ensembl.org/id/ENSBTAP00000041443.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P290", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P290" }, { "id": "PF14916", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14916" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCDC92/74 N-terminal", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 100, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P290", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P290" }, { "id": "PF14917", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14917" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Coiled coil protein 74 C-terminal", "eco_id": "ECO_0000259", "start_pos": 199, "end_pos": 322, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P1C8-1", "uniprot_ac": "A0ABI0P1C8", "uniprot_id": "A0ABI0P1C8_BOVIN", "mass": { "chemical_mass": 29179.0, "monoisotopic_mass": 29179.0 }, "refseq": {}, "gene_names": [ { "name": "CLIC6", "type": "recommended", "evidence": [ { "id": "A0ABI0P1C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8" } ] } ], "protein_names": [ { "name": "Chloride intracellular channel protein", "type": "recommended", "evidence": [ { "id": "A0ABI0P1C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1C8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CLIC6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000001753", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001753", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000046447", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046447", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03061", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03061", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507243", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507243", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NMDTEAP", "url": "https://omabrowser.org/oma/group/NMDTEAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "WGYLNNA", "url": "https://omabrowser.org/oma/group/WGYLNNA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LJG3", "url": "https://www.orthodb.org/?gene=A0A3Q1LJG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BAI4", "url": "https://www.orthodb.org/?gene=E1BAI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45476", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45476", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45476:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45476:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22441", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22441", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LJG3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMT3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMT3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1C8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1C8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAI4", "url": "https://www.uniprot.org/uniprotkb/E1BAI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BAI4-1", "url": "https://www.uniprot.org/uniprotkb/E1BAI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3V2", "url": "https://www.uniprot.org/uniprotkb/G3N3V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3V2-1", "url": "https://www.uniprot.org/uniprotkb/G3N3V2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MILCACRVESGTCNCETSSDEDLLFHLQAGCDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIYERNLLKALKKLDSYLNSPLPDEIDAYSTEEAAISGRKFLDGNELTLADCNLLPKLHIIKIVAKRYRDFEFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVAKRMKTK", "length": 258, "header": "tr|A0ABI0P1C8-1|A0ABI0P1C8_BOVIN Isoform 1 of Chloride intracellular channel protein OS=Bos taurus OX=9913 GN=CLIC6 PE=3 SV=1 CANONICAL=A0ABI0P1C8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJG3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8/entry#A0A3Q1LJG3-1", "sequence": { "sequence": "ACYEQPLQAGCDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIYERNLLKALKKLDSYLNSPLPDEIDAYSTEEAAISGRKFLDGNELTLADCNLLPKLHIIKIVAKRYRDFEFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVAKRMK", "length": 236, "header": "tr|A0A3Q1LJG3-1|A0ABI0P1C8_BOVIN Computationally mapped isoform of Chloride intracellular channel protein OS=Bos taurus OX=9913 GN=CLIC6 PE=3 SV=3 CANONICAL=A0ABI0P1C8-1" }, "locus": { "chromosome": "1", "start_pos": 781205, "end_pos": 765989, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078601.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078601.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056655.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056655.3" } ] } }, { "isoform_ac": "A0ABI0NMT3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8/entry#A0ABI0NMT3-1", "sequence": { "sequence": "MAESSDLLFHLQAGCDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANESENLLKALKKLDSYLNSPLPDEIDAYSTEEAAISGRKFLDGNELTLADCNLLPKLHIIKVCPSSYASSCTLLSMGFSQQVYWSGLPCPPPGSLLDLGIEPTSPAMQADFLPLRHQGSPFRNVNPSVQPLTY", "length": 257, "header": "tr|A0ABI0NMT3-1|A0ABI0P1C8_BOVIN Computationally mapped isoform of Chloride intracellular channel protein OS=Bos taurus OX=9913 GN=CLIC6 PE=3 SV=1 CANONICAL=A0ABI0P1C8-1" }, "locus": { "chromosome": "1", "start_pos": 780953, "end_pos": 775891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139624.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139624.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106918.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106918.1" } ] } }, { "isoform_ac": "A0ABI0P1C8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8/entry#A0ABI0P1C8-1", "sequence": { "sequence": "MILCACRVESGTCNCETSSDEDLLFHLQAGCDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIYERNLLKALKKLDSYLNSPLPDEIDAYSTEEAAISGRKFLDGNELTLADCNLLPKLHIIKIVAKRYRDFEFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVAKRMKTK", "length": 258, "header": "tr|A0ABI0P1C8-1|A0ABI0P1C8_BOVIN Isoform 1 of Chloride intracellular channel protein OS=Bos taurus OX=9913 GN=CLIC6 PE=3 SV=1 CANONICAL=A0ABI0P1C8-1" }, "locus": { "chromosome": "1", "start_pos": 780201, "end_pos": 765522, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139448.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139448.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104428.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104428.1" } ] } }, { "isoform_ac": "E1BAI4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8/entry#E1BAI4-1", "sequence": { "sequence": "LTNIHHDFVYLLFHLQAGCDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIYERNLLKALKKLDSYLNSPLPDEIDAYSTEEAAISGRKFLDGNELTLADCNLLPKLHIIKIVAKRYRDFEFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVAKRMK", "length": 244, "header": "tr|E1BAI4-1|A0ABI0P1C8_BOVIN Computationally mapped isoform of Chloride intracellular channel protein OS=Bos taurus OX=9913 GN=CLIC6 PE=3 SV=2 CANONICAL=A0ABI0P1C8-1" }, "locus": { "chromosome": "1", "start_pos": 780217, "end_pos": 765989, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002299.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002299.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002299.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002299.5" } ] } }, { "isoform_ac": "G3N3V2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8/entry#G3N3V2-1", "sequence": { "sequence": "MEGRQKAGCDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANESENLLKALKKLDSYLNSPLPDEIDAYSTEEAAISGRKFLDGNELTLADCNLLPKLHIIKVCPSSYVFLGGSHEASESLVLIPPSSQLLFSSLNPHSLKTSSVKAI", "length": 225, "header": "tr|G3N3V2-1|A0ABI0P1C8_BOVIN Computationally mapped isoform of Chloride intracellular channel protein OS=Bos taurus OX=9913 GN=CLIC6 PE=3 SV=3 CANONICAL=A0ABI0P1C8-1" }, "locus": { "chromosome": "1", "start_pos": 780327, "end_pos": 776651, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063511.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063511.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056615.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056615.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:507243", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507243", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q811Q2-1", "protein_name": "Chloride intracellular channel protein 6", "gene_name": "Clic6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEATEPKEVSSGSQGQPEGAVIEGPGEPGAADLEGREASEGAAEAPRDLGEGAEAMASGKEEGGCGQDGEIGEVQAQDPRPGPGTETPGTSGAPGEAEAAECDSEGALIPQSGGGAKRQQVQGTSSGLDAQGEAPEVPEDARREPEDPKASEAGEEAESGQEALGGSAPESQINPEVQGPVGDNMDTEAPAGEPQGSEGEPQGGGESSPQPQDEAIEIAAAEVGGHEPGELAGASAADAKGEGETLRKDGFEEAAPEEARVDSGENGFEEAAPEEARVDSGENRDQGRLQEETGEEEARPESGLKGPCEEAIQEKAPDGSLDGEEAKSTGHEESQVELSNHLAEETSAQGGEELGRVNGRRENGPASEEGDLGQEHDITLFVKAGSDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLVPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANDIYEKNLLRALKKLDSYLNSPLPDEIDAYSTEDVTVSQRKFLDGDELTLADCNLLPKLHIIKIVAKKYRGFEFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDAAKRMK", "length": 612 }, "evidence": [ { "id": "A0ABI0P1C8", "url": "https://omabrowser.org/oma/group/A0ABI0P1C8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BHB9-1", "protein_name": "Chloride intracellular channel protein 6", "gene_name": "Clic6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEATEPKEVAPGSQGQPEGATIEGPGEPGAADLEGREASEEAAEAPRDLGAGVEARASGKEEGGCGQDEGTGGAQAQDPRTGPEAETPGASGAPGEAEAAERDPEGAIPQGAEEAPSAQQVQGMSSGLDSQGEAPEVPGDSRREPEDPTASEAGEEAESGQEAQGGGALGLQINPEVQGLAGDNMDTEAPAGGPLGSESEPQGGGESSPQPQDEAIEIVTTEIGGNESGELAGASAADAAGEGETLGKDGSEEAASEDARVDAHENGDQGKLQEETGEEEARPEPELKGPCEGAIQEKPPDGSLDGEEAKSTEHEEESQAELSNHLAEEPSVQGGEELGRVNGRRENGPALEEGDPGQEHDITLFVKAGYDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLVPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIYEKNLLRALKKLDSYLNSPLPDEIDADSSEDVTVSQRKFLDGDELTLADCNLLPKLHIIKIVAKKYRDFEFPSEMTGIWRYLNNAYARDEFTNTCPADREIEHAYSDAAKRMK", "length": 596 }, "evidence": [ { "id": "A0ABI0P1C8", "url": "https://omabrowser.org/oma/group/A0ABI0P1C8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96NY7-1", "protein_name": "Chloride intracellular channel protein 6", "gene_name": "CLIC6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALGQEHDITLFVKVKLTALGCSRIAIKKYLRAGYDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIHEKNLLKALRKLDNYLNSPLPDEIDAYSTEDVTVSGRKFLDGDELTLADCNLLPKLHIIKIVAKKYRDFEFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVAKRMK", "length": 704 }, "evidence": [ { "id": "A0ABI0P1C8", "url": "https://omabrowser.org/oma/group/A0ABI0P1C8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "D4 dopamine receptor binding", "id": "GO:0031751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031751", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1C8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1C8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1C8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8" } ], "pmid": "" }, { "name": "D2 dopamine receptor binding", "id": "GO:0031749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031749", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1C8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8" } ], "pmid": "" }, { "name": "D3 dopamine receptor binding", "id": "GO:0031750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031750", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1C8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1C8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1C8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29823", "name": "", "equation": "chloride(in) = chloride(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MN01-1", "Q5E9B7-1", "Q9XSA7-1", "P35071-1", "P35526-1" ], "evidence": [ { "id": "29823", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29823" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "P35071", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "P35071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35071" } ] } ] }, { "uniprot_ac": "P35526", "gene_name": "CLIC5", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "P35526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35526" } ] } ] }, { "uniprot_ac": "Q5E9B7", "gene_name": "CLIC1", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "Q5E9B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9B7" } ] }, { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "Q5E9B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9B7" } ] } ] }, { "uniprot_ac": "Q9XSA7", "gene_name": "CLIC4", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "Q9XSA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XSA7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P1C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C8" }, { "id": "PS50405", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50405" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST C-terminal", "eco_id": "ECO_0000259", "start_pos": 85, "end_pos": 258, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P4P5-1", "uniprot_ac": "A0ABI0P4P5", "uniprot_id": "A0ABI0P4P5_BOVIN", "mass": { "chemical_mass": 75159.0, "monoisotopic_mass": 75159.0 }, "refseq": {}, "gene_names": [ { "name": "ABCG8", "type": "recommended", "evidence": [ { "id": "A0ABI0P4P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P5" } ] } ], "protein_names": [ { "name": "ATP-binding cassette sub-family G member 8", "type": "recommended", "evidence": [ { "id": "A0ABI0P4P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P5/entry#names_and_taxonomy" } ] }, { "name": "Sterolin-2", "type": "synonym", "evidence": [ { "id": "A0ABI0P4P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4P5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ABCG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P5", "locus": { "chromosome": "11", "start_pos": 26097106, "end_pos": 26079010, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016366", "url": "https://www.ensembl.org/id/ENSBTAG00000016366" } ] } } ], "crossref": [ { "id": "ENSBTAG00000016366", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016366", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "508829", "url": "https://www.ncbi.nlm.nih.gov/gene/508829", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LUZ4", "url": "https://www.orthodb.org/?gene=A0A3Q1LUZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N3K2", "url": "https://www.orthodb.org/?gene=F1N3K2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48041", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48041", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48041:SF71", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48041:SF71", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1369062", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1369062", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LUZ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4P5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4P5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3K2", "url": "https://www.uniprot.org/uniprotkb/F1N3K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3K2-1", "url": "https://www.uniprot.org/uniprotkb/F1N3K2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEEAPKKTGLERSTAPQDDLQGLQDSVFSSESDNSLYFTYSGQPNTLEVRDLSYQMDMASQVPWFKQLAHFKMPWTSHKDSCEQGIQNLSFKMRSGQMLAVIGSSGCGRASLLDVITGRGPGGKIKSGQIWINGQPSTAQLVRKCVAHVRQHDQLLPNLTVRETLAFVAQLRLPRNFSQAQRDKRVDDVIAELRLRQCANTRVGNIYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLLSIHQPRSDIFGLFDLVLLMTSGTTIYLGAAQHMVQYFTAVGHPCPRYSNPADYYVDLTSIDRRSKEQEVATRETARSLAALFKEKVRGFDDFLWTAESREQSVGTCVQSPAPDTNLFQAPTKLPGPLQQFAILIRRQISNDFRDLPTLLIHGAEACLMSLIIGFLYYGHGAIQLSLTDTAALLFMIGALVPFNVILDVISKCHSERALLYYELEDGLYTAGPYFFAKILGEFPEHCVYIIIYGMPIYWLANLRPGLEPFLLHFLLVWLVVFCCRVMALAAAALLPTFHMSSFFGNALYNSFYLTGGFMISLDNLWTVPALISKVSFLRWCFEGLMKIQFSGHAYYMEAGNITIRIPGDMILNSMGLNSYPLYAIYFFVIGISCGFVILYYLSLRFIKQKSSQDW", "length": 670, "header": "tr|A0ABI0P4P5-1|A0ABI0P4P5_BOVIN Isoform 1 of ATP-binding cassette sub-family G member 8 OS=Bos taurus OX=9913 GN=ABCG8 PE=3 SV=1 CANONICAL=A0ABI0P4P5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LUZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P5/entry#A0A3Q1LUZ4-1", "sequence": { "sequence": "MPLSDVPLASVCLCVISAAGRAHSPCLWEGLPERNAGSQTRGCPALGSRQHWPWSAAAKPKGNCRVKAQTLQGPMAEEAPKKTGLERSTAPQDDLMDMASQVPWFKQLAHFKMPWTSHKDSCEQGIQNLSFKMRSGQMLAVIGSSGCGRASLLDVITGRGPGGKIKSGQIWINGQPSTAQLVRKCVAHVRQHDQLLPNLTVRETLAFVAQLRLPRNFSQAQRDKRVDDVIAELRLRQCANTRVGNIYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLLSIHQPRSDIFGLFDLVLLMTSGTTIYLGAAQHMVQYFTAVGHPCPRYSNPADYYVDLTSIDRRSKEQEVATRETARSLAALFKEKVRGFDDFLWTAESREQSVGTCVQSPAPDTNLFQAPTKLPGPLQQFAILIRRQISNDFRDLPTLLIHGAEACLMSLIIGFLYYGHGAIQLSLTDTAALLFMIGALVPFNVILDVISKCHSERALLYYELEDGLYTAGPYFFAKILGEFPEHCVYIIIYGMPIYWLANLRPGLEPFLLHFLLVWLVVFCCRVMALAAAALLPTFHMSSFFGNALYNSFYLTGGFMISLDNLWTVPALISKVSFLRWCFEGLMKIQFSGHAYYMEAGNITIRIPGDMILNSMGLNSYPLYAIYFFVIGISCGFVILYYLSLRFIKQKSSQDW", "length": 709, "header": "tr|A0A3Q1LUZ4-1|A0ABI0P4P5_BOVIN Computationally mapped isoform of ATP-binding cassette sub-family G member 8 OS=Bos taurus OX=9913 GN=ABCG8 PE=3 SV=3 CANONICAL=A0ABI0P4P5-1" }, "locus": { "chromosome": "11", "start_pos": 26096938, "end_pos": 26079209, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075461.3", "url": "https://www.ensembl.org/id/ENSBTAT00000075461.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059076.3", "url": "https://www.ensembl.org/id/ENSBTAP00000059076.3" } ] } }, { "isoform_ac": "A0ABI0P4P5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P5/entry#A0ABI0P4P5-1", "sequence": { "sequence": 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"id": "ENSBTAT00000146009.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146009.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105756.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105756.1" } ] } }, { "isoform_ac": "F1N3K2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P5/entry#F1N3K2-1", "sequence": { "sequence": "MPLSDVPLASVCLCVISAAGRAHSPCLWEGLPERNAGSQTRGCPALGSRQHWPWSAAAKPKGNCRVKAQTLQGPMAEEAPKKTGLERSTAPQDDLQGLQDSVFSSESDNSLYFTYSGQPNTLEVRDLSYQMDMASQVPWFKQLAHFKMPWTSHKDSCEQGIQNLSFKMRSGQMLAVIGSSGCGRASLLDVITGRGPGGKIKSGQIWINGQPSTAQLVRKCVAHVRQHDQLLPNLTVRETLAFVAQLRLPRNFSQAQRDKRVDDVIAELRLRQCANTRVGNIYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLLSIHQPRSDIFGLFDLVLLMTSGTTIYLGAAQHMVQYFTAVGHPCPRYSNPADYYVDLTSIDRRSKEQEVATRETARSLAALFKEKVRGFDDFLWTAESREQSVGTCVQSPAPDTNLFQAPTKLPGPLQQFAILIRRQISNDFRDLPTLLIHGAEACLMSLIIGFLYYGHGAIQLSLTDTAALLFMIGALVPFNVILDVISKCHSERALLYYELEDGLYTAGPYFFAKILGEFPEHCVYIIIYGMPIYWLANLRPGLEPFLLHFLLVWLVVFCCRVMALAAAALLPTFHMSSFFGNALYNSFYLTGGFMISLDNLWTVPALISKVSFLRWCFEGLMKIQFSGHAYYMEAGNITIRIPGDMILNSMGLNSYPLYAIYFFVIGISCGFVILYYLSLRFIKQKSSQDW", "length": 744, "header": "tr|F1N3K2-1|A0ABI0P4P5_BOVIN Computationally mapped isoform of ATP-binding cassette sub-family G member 8 OS=Bos taurus OX=9913 GN=ABCG8 PE=3 SV=4 CANONICAL=A0ABI0P4P5-1" }, "locus": { "chromosome": "11", "start_pos": 26096938, "end_pos": 26079209, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021770.8", "url": "https://www.ensembl.org/id/ENSBTAT00000021770.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021770.7", "url": "https://www.ensembl.org/id/ENSBTAP00000021770.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1369062", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1369062", "resource": "Reactome", "description": "ABC transporters in lipid homeostasis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4P5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P5" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": 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"https://www.reactome.org/PathwayBrowser/#R-BTA-1963642", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6785631", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6785631", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6811558", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8847993", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8847993", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8863795", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8863795", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024841944", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024841944", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NYL1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYL1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0A2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P323", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P323", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P323-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P323-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MPD0", "url": "https://www.uniprot.org/uniprotkb/F1MPD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MPD0-1", "url": "https://www.uniprot.org/uniprotkb/F1MPD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEIYSPDMSEGAAERSSSPSTQLSADPSLDGLPAAEDMPETQTEDGRSPGLVGLTLPCCVCLETERLRGCLNSEKICIVPILACLVSLCLCIAGLKWVFVDKIFEYDSPTHLDPGGLGQDPIISLDPTAASAAVWVSAKAYTSPVSRAQSETEVRVTVQVDNALGSSEPSAVPTPKNRIFAFSFRPSTAPSLPSPTRSPDVRTPKAATQPPSTETNLQTAPKLSTSTSTAGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNTMMNVANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESIISESHSVIVMSSVENSRHSSPTGGPRGRLNGLGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSTTVSMPSMAVSPFVEEERPLLLVTPPRLREKYDHHAQQFNSFHCNPAHESNSLPPSPLRIVEDEEYETTQEYEPAQEPVKKLTNSSRRAKRTKPNGHIAHRLEMDNNTGADSSNSESETEDERVGEDTPFLAIQNPLAASLEAAPAFRLVDSRTNPTGRFSPQEELQARLSGVIANQDPIAV", "length": 701, "header": "tr|A0ABI0P0A2-1|A0ABI0P0A2_BOVIN Isoform 1 of Pro-neuregulin-1, membrane-bound isoform OS=Bos taurus OX=9913 GN=NRG1 PE=3 SV=1 CANONICAL=A0ABI0P0A2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NYL1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0A2/entry#A0ABI0NYL1-1", "sequence": { "sequence": "MEIYSPDMSEGAAERSSSPSTQLSADPSLDGLPAAEDMPETQTEDGRSPGLVGLTLPCCVCLETERLRGCLNSEKICIVPILACLVSLCLCIAGLKWVFVDKIFEYDSPTHLDPGGLGQDPIISLDPTAASAAVWVSAKAYTSPVSRAQSETEVRVTVQVDNALGSSEPSAVPTPKNRIFAFSFRPSTAPSLPSPTRSPDVRTPKAATQPPSTETNLQTAPKLSTSTSTAGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQTQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNTMMNVANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESIISESHSVIVMSSVENSRHSSPTGGPRGRLNGLGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSTTVSMPSMAVSPFVEEERPLLLVTPPRLREKYDHHAQQFNSFHCNPAHESNSLPPSPLRIVEDEEYETTQEYEPAQEPVKKLTNSSRRAKRTKPNGHIAHRLEMDNNTGADSSNSESETEDERVGEDTPFLAIQNPLAASLEAAPAFRLVDSRTNPTGRFSPQEELQARLSGVIANQDPIAV", "length": 696, "header": "tr|A0ABI0NYL1-1|A0ABI0P0A2_BOVIN Computationally mapped isoform of Pro-neuregulin-1, membrane-bound isoform OS=Bos taurus OX=9913 GN=NRG1 PE=3 SV=1 CANONICAL=A0ABI0P0A2-1" }, "locus": { "chromosome": "27", "start_pos": 28651516, "end_pos": 28529967, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152549.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152549.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105400.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105400.1" } ] } }, { "isoform_ac": "A0ABI0P0A2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0A2/entry#A0ABI0P0A2-1", "sequence": { "sequence": "MEIYSPDMSEGAAERSSSPSTQLSADPSLDGLPAAEDMPETQTEDGRSPGLVGLTLPCCVCLETERLRGCLNSEKICIVPILACLVSLCLCIAGLKWVFVDKIFEYDSPTHLDPGGLGQDPIISLDPTAASAAVWVSAKAYTSPVSRAQSETEVRVTVQVDNALGSSEPSAVPTPKNRIFAFSFRPSTAPSLPSPTRSPDVRTPKAATQPPSTETNLQTAPKLSTSTSTAGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNTMMNVANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESIISESHSVIVMSSVENSRHSSPTGGPRGRLNGLGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSTTVSMPSMAVSPFVEEERPLLLVTPPRLREKYDHHAQQFNSFHCNPAHESNSLPPSPLRIVEDEEYETTQEYEPAQEPVKKLTNSSRRAKRTKPNGHIAHRLEMDNNTGADSSNSESETEDERVGEDTPFLAIQNPLAASLEAAPAFRLVDSRTNPTGRFSPQEELQARLSGVIANQDPIAV", "length": 701, "header": "tr|A0ABI0P0A2-1|A0ABI0P0A2_BOVIN Isoform 1 of Pro-neuregulin-1, membrane-bound isoform OS=Bos taurus OX=9913 GN=NRG1 PE=3 SV=1 CANONICAL=A0ABI0P0A2-1" }, "locus": { "chromosome": "27", "start_pos": 28651516, "end_pos": 28529967, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148013.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148013.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107559.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107559.1" } ] } }, { "isoform_ac": "A0ABI0P323-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0A2/entry#A0ABI0P323-1", "sequence": { "sequence": "MEIYSPDMSEGAAERSSSPSTQLSADPSLDGLPAAEDMPETQTEDGRSPGLVGLTLPCCVCLETERLRGCLNSEKICIVPILACLVSLCLCIAGLKWVFVDKIFEYDSPTHLDPGGLGQDPIISLDPTAASAAVWVSAKAYTSPVSRAQSETEVRVTVQVDNALGSSEPSAVPTPKNRIFAFSFRPSTAPSLPSPTRSPDVRTPKAATQPPSTETNLQTAPKLSTSTSTAGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNTMMNVANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESIISESHSVIVMSSVENSRHSSPTGGPRGRLNGLGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSTTVSMPSMAVSPFVEEERPLLLVTPPRLREKYDHHAQQFNSFHCNPAHESNSLPPSPLRIVEDEEYETTQEYEPAQEPVKKLTNSSRRAKRTKPNGHIAHRLEMDNNTGADSSNSESETEDERVGEDTPFLAIQNPLAASLEAAPAFRLVDSRTNPTGRFSPQEELQARLSGVIANQDPIAV", "length": 693, "header": "tr|A0ABI0P323-1|A0ABI0P323_BOVIN Computationally mapped isoform of Pro-neuregulin-1, membrane-bound isoform OS=Bos taurus OX=9913 GN=NRG1 PE=3 SV=1 CANONICAL=A0ABI0P0A2-1" }, "locus": { "chromosome": "27", "start_pos": 28651516, "end_pos": 28529967, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150035.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150035.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105062.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105062.1" } ] } }, { "isoform_ac": "F1MPD0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0A2/entry#F1MPD0-1", "sequence": { "sequence": "MEIYSPDMSEGAAERSSSPSTQLSADPSLDGLPAAEDMPETQTEDGRSPGLVGLTLPCCVCLETERLRGCLNSEKICIVPILACLVSLCLCIAGLKWVFVDKIFEYDSPTHLDPGGLGQDPIISLDPTAASAAVWVSAKAYTSPVSRAQSETEVRVTVQVDNALGSSEPSAVPTPKNRIFAFSFRPSTAPSLPSPTRSPDVRTPKAATQPPSTETNLQTAPKLSTSTSTAGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNTMMNVANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESIISESHSVIVMSSVENSRHSSPTGGPRGRLNGLGGPRECNSFLRHARETPDSYRDSPHSERHNLIAELRRNKAHRSKCMQIQLSATHLRASSIPHLGFIL", "length": 523, "header": "tr|F1MPD0-1|A0ABI0P0A2_BOVIN Computationally mapped isoform of Pro-neuregulin-1, membrane-bound isoform OS=Bos taurus OX=9913 GN=NRG1 PE=3 SV=3 CANONICAL=A0ABI0P0A2-1" }, "locus": { "chromosome": "27", "start_pos": 28650421, "end_pos": 28529967, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047662.6", "url": "https://www.ensembl.org/id/ENSBTAT00000047662.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044846.4", "url": "https://www.ensembl.org/id/ENSBTAP00000044846.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1227986", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1227986", "resource": "Reactome", "description": "Signaling by ERBB2" }, { "id": "R-BTA-1236394", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1236394", "resource": "Reactome", "description": "Signaling by ERBB4" }, { "id": "R-BTA-1250196", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1250196", "resource": "Reactome", "description": "SHC1 events in ERBB2 signaling" }, { "id": "R-BTA-1250342", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1250342", "resource": "Reactome", "description": "PI3K events in ERBB4 signaling" }, { "id": "R-BTA-1250347", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1250347", "resource": "Reactome", "description": "SHC1 events in ERBB4 signaling" }, { "id": "R-BTA-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-BTA-1306955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1306955", "resource": "Reactome", "description": "GRB7 events in ERBB2 signaling" }, { "id": "R-BTA-1358803", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1358803", "resource": "Reactome", "description": "Downregulation of ERBB2:ERBB3 signaling" }, { "id": "R-BTA-1963640", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1963640", "resource": "Reactome", "description": "GRB2 events in ERBB2 signaling" }, { "id": "R-BTA-1963642", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1963642", "resource": "Reactome", "description": "PI3K events in ERBB2 signaling" }, { "id": "R-BTA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" }, { "id": "R-BTA-6785631", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6785631", "resource": "Reactome", "description": "ERBB2 Regulates Cell Motility" }, { "id": "R-BTA-6811558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811558", "resource": "Reactome", "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" }, { "id": "R-BTA-8847993", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8847993", "resource": "Reactome", "description": "ERBB2 Activates PTK6 Signaling" }, { "id": "R-BTA-8863795", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8863795", "resource": "Reactome", "description": "Downregulation of ERBB2 signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480WER8-1", "protein_name": "Pro-neuregulin-1, membrane-bound isoform", "gene_name": "NRG1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSERREGRGKGKGKKDRGSGKKPALSAGGQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLKFKWFKNGNELNRKNKPQNIKIQKRPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVDSNEIITGMPASTERAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQTQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMVNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIMMSSVENSRHSSPTGGPRGRLNGLGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPMSSTTVSMPSMAISPFVEEERPLLLVTPPRLREKYDHHSQQFSSAHCNPAHESNSLPPSPLRIVEDEEYETTQEYEPAQEPDKKLTNSRRAKRTKPNGHIANRSEMDSNTSAESSNSESETEDERVGEDTPFLGIQNPLAASLEVAPAFRLADGRTNPAGRFSPQEELQARLSSVIANQDPIAV", "length": 638 }, "evidence": [ { "id": "A0ABI0P0A2", "url": "https://omabrowser.org/oma/group/A0ABI0P0A2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7HEH2-1", "protein_name": "Pro-neuregulin-1, membrane-bound isoform", "gene_name": "Nrg1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRWRRAPRRRLGTSPSAPHPWPAGGSPPLLPLLPPLLLLLGTAALAPGAAAERAAPAGASVCYSSPPSVGSVQELARRAAVVIEGKVHPPRRQQGALDRKAAGEAGAGVRGQHAQDPPPSQDPPPAANWTLPTGSPAPNTDQPGDPSPYLVKVHQVWAVKAGGLKKDSLLTVRLDTWGHPSFLSCGRLKEDSRYIFFMEPDANSSGRAPPAFRASYPPLETGRNLKKEVSRVLCKRCALPPRLKEMKSQESAAGSKLVLRCETSSEYPELRFKWFKNGSELNKRTKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVDSNEFITGMPASTERAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRQKLHDRLRQSLRSERNNMVNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREVETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESIVSESHSVIMMSSVENSRHSSPAGGPRGRLHGLGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFVEEERPLLLVTPPRLREKKYDHHPQQLNSFHHNPAHQSTSLPPSPLRIVEDEEYETTQEYEPVQEPVKKLTNSRRAKRTKPNGHIANRLEMDSNTSSMSSNSESETEDERVGEDTPFLGIQNPLAASLEAAPAFRLADSRTNPVGRFSTQEELQARLSSVIANQDPIAV", "length": 849 }, "evidence": [ { "id": "A0ABI0P0A2", "url": "https://omabrowser.org/oma/group/A0ABI0P0A2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P43322-1", "protein_name": "Pro-neuregulin-1, membrane-bound isoform", "gene_name": "Nrg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSERKEGRGKGKGKKKDRGSRGKPGPAEGDPSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPENIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEFITGMPASTETAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLIKCAEKEKTFCVNGGECFTVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYMTSRRKRQETEKPLERKLDHSLVKESKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRQKLHDRLRQSLRSERSNLVNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREVETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESVISESNSVIMMSSVENSRHSSPAGGPRGRLHGLGGPRDNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSVAVSPFVEEERPLLLVTPPRLREKKYDHHPQQLNSFHHNPAHQSTSLPPSPLRIVEDEEYETTQEYESVQEPVKKVTNSRRAKRTKPNGHIANRLEMDSNTSSVSSNSESETEDERVGEDTPFLGIQNPLAASLEVAPAFRLAESRTNPAGRFSTQEELQARLSSVIANQDPIAV", "length": 662 }, "evidence": [ { "id": "A0ABI0P0A2", "url": "https://omabrowser.org/oma/group/A0ABI0P0A2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q02297-1", "protein_name": "Pro-neuregulin-1, membrane-bound isoform", "gene_name": "NRG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQEEIQARLSSVIANQDPIAV", "length": 640 }, "evidence": [ { "id": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P147-1", "uniprot_ac": "A0ABI0P147", "uniprot_id": "A0ABI0P147_BOVIN", "mass": { "chemical_mass": 18353.0, "monoisotopic_mass": 18353.0 }, "refseq": {}, "gene_names": [ { "name": "SNRPD3", "type": "recommended", "evidence": [ { "id": "A0ABI0P147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147" } ] } ], "protein_names": [ { "name": "Small nuclear ribonucleoprotein Sm D3", "type": "recommended", "evidence": [ { "id": "A0ABI0P147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147/entry#names_and_taxonomy" } ] }, { "name": "Sm-D3", "type": "synonym", "evidence": [ { "id": "A0ABI0P147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147/entry#names_and_taxonomy" } ] }, { "name": "snRNP core protein D3", "type": "synonym", "evidence": [ { "id": "A0ABI0P147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P147", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147#function" }, { "database": "UniProtKB", "id": "RU365050", "url": "https://www.uniprot.org/uniprotkb/RU365050#function" }, { "database": "UniProtKB", "id": "ARBA00056968", "url": "https://www.uniprot.org/uniprotkb/ARBA00056968#function" }, { "database": "UniProtKB", "id": "F1MZ00", "url": "https://www.uniprot.org/uniprotkb/F1MZ00#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P147", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SNRPD3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147", "locus": { "chromosome": "17", "start_pos": 71496420, "end_pos": 71503668, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021262", "url": "https://www.ensembl.org/id/ENSBTAG00000021262" } ] } } ], "crossref": [ { "id": "ENSBTAG00000021262", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021262", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01721", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01721", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027141", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027141", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MZ00", "url": "https://www.orthodb.org/?gene=F1MZ00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23338", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23338", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-111367", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111367", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-191859", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-191859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72165", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-73856", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73856", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-77588", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77588", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9943411", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9943411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0P147", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P147-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZ00", "url": "https://www.uniprot.org/uniprotkb/F1MZ00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZ00-1", "url": "https://www.uniprot.org/uniprotkb/F1MZ00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRIDEALHANNSGRVPAQRKRPGNESLLHSGSSRKSSLPAEMSIGVPIKVLHEAEGHIVTCETNTGEVYRGKLIEAEDNMNCQMSNITVTYRDGRVAQLEQVYIRGSKIRFLILPDMLKNAPMLKSMKNKNQGSGAGRGKAAILKAQVAARGRGRGMGRGNIFQKRR", "length": 167, "header": "tr|A0ABI0P147-1|A0ABI0P147_BOVIN Isoform 1 of Small nuclear ribonucleoprotein Sm D3 OS=Bos taurus OX=9913 GN=SNRPD3 PE=3 SV=1 CANONICAL=A0ABI0P147-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P147-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147/entry#A0ABI0P147-1", "sequence": { "sequence": "MRIDEALHANNSGRVPAQRKRPGNESLLHSGSSRKSSLPAEMSIGVPIKVLHEAEGHIVTCETNTGEVYRGKLIEAEDNMNCQMSNITVTYRDGRVAQLEQVYIRGSKIRFLILPDMLKNAPMLKSMKNKNQGSGAGRGKAAILKAQVAARGRGRGMGRGNIFQKRR", "length": 167, "header": "tr|A0ABI0P147-1|A0ABI0P147_BOVIN Isoform 1 of Small nuclear ribonucleoprotein Sm D3 OS=Bos taurus OX=9913 GN=SNRPD3 PE=3 SV=1 CANONICAL=A0ABI0P147-1" }, "locus": { "chromosome": "17", "start_pos": 71505393, "end_pos": 71496578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147556.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147556.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107583.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107583.1" } ] } }, { "isoform_ac": "F1MZ00-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147/entry#F1MZ00-1", "sequence": { "sequence": "MSIGVPIKVLHEAEGHIVTCETNTGEVYRGKLIEAEDNMNCQMSNITVTYRDGRVAQLEQVYIRGSKIRFLILPDMLKNAPMLKSMKNKNQGSGAGRGKAAILKAQVAARGRGRGMGRGNIFQKRR", "length": 126, "header": "tr|F1MZ00-1|A0ABI0P147_BOVIN Computationally mapped isoform of Small nuclear ribonucleoprotein Sm D3 OS=Bos taurus OX=9913 GN=SNRPD3 PE=3 SV=2 CANONICAL=A0ABI0P147-1" }, "locus": { "chromosome": "17", "start_pos": 71501715, "end_pos": 71496578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028330.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028330.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028330.5", "url": "https://www.ensembl.org/id/ENSBTAP00000028330.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-111367", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-111367", "resource": "Reactome", "description": "SLBP independent Processing of Histone Pre-mRNAs" }, { "id": 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"https://www.uniprot.org/uniprotkb/A0ABI0P147" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P147", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P147", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147" } ], "pmid": "" }, { "name": "U4 snRNP", "id": "GO:0005687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005687", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P147", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P147", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P147" } ], 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Classification" ] }, { "id": "IPR039578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:319086", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:319086", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FMHSVGQ", "url": "https://omabrowser.org/oma/group/FMHSVGQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N366", "url": "https://www.orthodb.org/?gene=F1N366", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14261", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14261", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14261:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14261:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01291", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01291", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6788467", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6788467", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0P2M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2M9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N366", "url": "https://www.uniprot.org/uniprotkb/F1N366", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N366-1", "url": "https://www.uniprot.org/uniprotkb/F1N366-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGGGYRVPSAQTRPHTEREEGCDFGVLRGRGGSPEKPERGQASGSAPALPLGTWGLQIRGAGSTAQPGLVLRLLLLCTVATGKCSGKYHELLLQLQRQADLMQDPSTLLDPYIHLQGLHSPVLQEHCRERPGDFPSEDALWRLSRQDFLQTLNTTLGLILRMLSALQQDLPEAAHQQAEMNVRGFGNNIHCMAQLLRGSSDPKAAEPTQPGPGPTPLPPTPPSSTFQRKLRNCGFLRGYHRFMRTAGQVLRGWGERQGRSRRHSPCRALKRGARRTRPFPEIRRLAPRGQPPR", "length": 294, "header": "tr|A0ABI0P2M9-1|A0ABI0P2M9_BOVIN Isoform 1 of Oncostatin M OS=Bos taurus OX=9913 GN=OSM PE=3 SV=1 CANONICAL=A0ABI0P2M9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P2M9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M9/entry#A0ABI0P2M9-1", "sequence": { "sequence": "MRGGGYRVPSAQTRPHTEREEGCDFGVLRGRGGSPEKPERGQASGSAPALPLGTWGLQIRGAGSTAQPGLVLRLLLLCTVATGKCSGKYHELLLQLQRQADLMQDPSTLLDPYIHLQGLHSPVLQEHCRERPGDFPSEDALWRLSRQDFLQTLNTTLGLILRMLSALQQDLPEAAHQQAEMNVRGFGNNIHCMAQLLRGSSDPKAAEPTQPGPGPTPLPPTPPSSTFQRKLRNCGFLRGYHRFMRTAGQVLRGWGERQGRSRRHSPCRALKRGARRTRPFPEIRRLAPRGQPPR", "length": 294, "header": "tr|A0ABI0P2M9-1|A0ABI0P2M9_BOVIN Isoform 1 of Oncostatin M OS=Bos taurus OX=9913 GN=OSM PE=3 SV=1 CANONICAL=A0ABI0P2M9-1" }, "locus": { "chromosome": "17", "start_pos": 69300160, "end_pos": 69283369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150459.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150459.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104851.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104851.1" } ] } }, { "isoform_ac": "F1N366-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M9/entry#F1N366-1", "sequence": { "sequence": "MRAQRMQRTLLSLVLRLLLLCTVATGKCSGKYHELLLQLQRQADLMQDPSTLLDPYIHLQGLHSPVLQEHCRERPGDFPSEDALWRLSRQDFLQTLNTTLGLILRMLSALQQDLPEAAHQQAEMNVRGFGNNIHCMAQLLRGSSDPKAAEPTQPGPGPTPLPPTPPSSTFQRKLRNCGFLRGYHRFMRTAGQVLRGWGERQGRSRRHSPCRALKRGARRTRPFPEIRRLAPRGQPPR", "length": 237, "header": "tr|F1N366-1|A0ABI0P2M9_BOVIN Computationally mapped isoform of Oncostatin M OS=Bos taurus OX=9913 GN=OSM PE=3 SV=3 CANONICAL=A0ABI0P2M9-1" }, "locus": { "chromosome": "17", "start_pos": 69286246, "end_pos": 69283369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021515.6", "url": "https://www.ensembl.org/id/ENSBTAT00000021515.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021515.5", "url": "https://www.ensembl.org/id/ENSBTAP00000021515.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 216, "start_aa": "Thr", "end_pos": 216, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr216", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", 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"common_name": "Human" }, { "uniprot_canonical_ac": "P53347-1", "protein_name": "Oncostatin-M", "gene_name": "Osm", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQTRLLRTLLSLTLSLLILSMALANRGCSNSSSQLLSQLQNQANLTGNTESLLEPYIRLQNLNTPDLRAACTQHSVAFPSEDTLRQLSKPHFLSTVYTTLDRVLYQLDALRQKFLKTPAFPKLDSARHNILGIRNNVFCMARLLNHSLEIPEPTQTDSGASRSTTTPDVFNTKIGSCGFLWGYHRFMGSVGRVFREWDDGSTRSRRQSPLRARRKGTRRIRVRHKGTRRIRVRRKGTRRIWVRRKGSRKIRPSRSTQSPTTRA", "length": 263 }, "evidence": [ { "id": "A0ABI0P2M9", "url": "https://omabrowser.org/oma/group/A0ABI0P2M9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q65Z15-1", "protein_name": "Oncostatin-M", "gene_name": "Osm", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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], "pmid": "" }, { "name": "regulation of signaling", "id": "GO:0023051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023051", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M9" } ], "pmid": "" }, { "name": "regulation of cell communication", "id": "GO:0010646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010646", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M9" } ], "pmid": "" }, { "name": "positive regulation of biosynthetic process", "id": "GO:0009891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009891", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "oncostatin-M receptor binding", "id": "GO:0005147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005147", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M9" } ], "pmid": "" }, { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], 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{ "database": "UniProtKB", "id": "ARBA00037714", "url": "https://www.uniprot.org/uniprotkb/ARBA00037714#function" }, { "database": "UniProtKB", "id": "A0A3Q1LPX4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPX4#function" }, { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HMGCS1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2", "locus": { "chromosome": "20", "start_pos": 31456871, "end_pos": 31431059, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011839", "url": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2A2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RJG0", "url": "https://www.uniprot.org/uniprotkb/F6RJG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RJG0-1", "url": "https://www.uniprot.org/uniprotkb/F6RJG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNSLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVAMLIGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYRKKIRARWQKEGNDRDFTLNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASSELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKIVASICDLKSRLDSRTCVAPDIFAENMKLREDTHHLANYIPQSSIDSLFEGTWYLVRVDEKHRRTYARRPSLNDDTLNEGVGLVHPSTTAEHIPSPAKKVPRLPATAAEPEAAVISNGEH", "length": 520, "header": "tr|A0ABI0P2A2-1|A0ABI0P2A2_BOVIN Isoform 1 of Hydroxymethylglutaryl-CoA synthase OS=Bos taurus OX=9913 GN=HMGCS1 PE=1 SV=1 CANONICAL=A0ABI0P2A2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPX4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2/entry#A0A3Q1LPX4-1", "sequence": { "sequence": "MLQVPEGGDRVTDLETAVLYPSRSSFTMPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNSLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVAMLIGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYRKKIRARWQKEGNDRDFTLNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASSELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKIVASICDLKSRLDSRTCVAPDIFAENMKLREDTHHLANYIPQSSIDSLFEGTWYLVRVDEKHRRTYARRPSLNDDTLNEGVGLVHPSTTAEHIPSPAKKVPRLPATAAEPEAAVISNGEH", "length": 547, "header": "tr|A0A3Q1LPX4-1|A0ABI0P2A2_BOVIN Computationally mapped isoform of Hydroxymethylglutaryl-CoA synthase OS=Bos taurus OX=9913 GN=HMGCS1 PE=1 SV=2 CANONICAL=A0ABI0P2A2-1" }, "locus": { "chromosome": "20", "start_pos": 31453649, "end_pos": 31435638, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085392.3", "url": "https://www.ensembl.org/id/ENSBTAT00000085392.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057020.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057020.2" } ] } }, { "isoform_ac": "A0ABI0P2A2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2/entry#A0ABI0P2A2-1", "sequence": { "sequence": "MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNSLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVAMLIGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYRKKIRARWQKEGNDRDFTLNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASSELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKIVASICDLKSRLDSRTCVAPDIFAENMKLREDTHHLANYIPQSSIDSLFEGTWYLVRVDEKHRRTYARRPSLNDDTLNEGVGLVHPSTTAEHIPSPAKKVPRLPATAAEPEAAVISNGEH", "length": 520, "header": "tr|A0ABI0P2A2-1|A0ABI0P2A2_BOVIN Isoform 1 of Hydroxymethylglutaryl-CoA synthase OS=Bos taurus OX=9913 GN=HMGCS1 PE=1 SV=1 CANONICAL=A0ABI0P2A2-1" }, "locus": { "chromosome": "20", "start_pos": 31453649, "end_pos": 31445855, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152898.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152898.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107326.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107326.1" } ] } }, { "isoform_ac": "F6RJG0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2/entry#F6RJG0-1", "sequence": { "sequence": "HYPFVGRSLSTATARSYLGECPEWRRRYQLITRTETTTVRANKIRRKNSFTMPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNSLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVAMLIGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYRKKIRARWQKEGNDRDFTLNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASSELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKIVASICDLKSRLDSRTCVAPDIFAENMKLREDTHHLANYIPQSSIDSLFEGTWYLVRVDEKHRRTYARRPSLNDDTLNEGVGLVHPSTTAEHIPSPAKKVPRLPATAAEPEAAVISNGEH", "length": 571, "header": "tr|F6RJG0-1|A0ABI0P2A2_BOVIN Computationally mapped isoform of Hydroxymethylglutaryl-CoA synthase OS=Bos taurus OX=9913 GN=HMGCS1 PE=1 SV=2 CANONICAL=A0ABI0P2A2-1" }, "locus": { "chromosome": "20", "start_pos": 31453649, "end_pos": 31431224, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015713.5", "url": "https://www.ensembl.org/id/ENSBTAT00000015713.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015713.4", "url": "https://www.ensembl.org/id/ENSBTAP00000015713.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 393, "start_aa": "Thr", "end_pos": 393, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr393", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:407767", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:407767", "resource": "KEGG Pathway" }, { "id": "R-BTA-9969896", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9969896", "resource": "Reactome", "description": "Lanosterol biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "pmid": "" }, { "name": "hydroxymethylglutaryl-CoA synthase activity", "id": "GO:0004421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004421", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "isopentenyl diphosphate biosynthetic process, mevalonate pathway", "id": "GO:0019287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019287", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "pmid": "" }, { "name": "geranylgeranyl diphosphate biosynthetic process", "id": "GO:0033386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033386", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process via desmosterol", "id": "GO:0033489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033489", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process via lathosterol", "id": "GO:0033490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033490", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "pmid": "" }, { "name": "farnesyl diphosphate biosynthetic process, mevalonate pathway", "id": "GO:0010142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010142", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "pmid": "" }, { "name": "zymosterol biosynthetic process", "id": "GO:0036197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036197", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "pmid": "" }, { "name": "acetyl-CoA metabolic process", "id": "GO:0006084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006084", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process", "id": "GO:0006695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006695", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10188", "name": "", "equation": "acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KIE6-1", "A0ABI0P2A2-1" ], "evidence": [ { "id": "10188", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10188" } ] }, { "id": "R-BTA-191323", "name": "HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-191293" ], "output_participant_list": [], "enzyme_list": [ "A0ABI0P2A2-1" ], "evidence": [ { "id": "R-BTA-191323", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-191323" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-191293", "participant_name": "ACA-CoA [cytosol]", "crossref": [ { "id": "57286", "database": "ChEBI", "url": "" }, { "id": "ZINC000096014521", "database": "ZINC", "url": "" }, { "id": "C00332", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0ABI0P2A2", "gene_name": "HMGCS1", "activity": [ { "ec_number": "2.3.3.10", "activity": "acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+).", "evidence": [ { "id": "A0ABI0P2A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ] }, { "ec_number": "2.3.3.10", "activity": "", "evidence": [ { "id": "A0ABI0P2A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" } ] } ] }, { "uniprot_ac": "Q2KIE6", "gene_name": "HMGCS2", "activity": [ { "ec_number": "2.3.3.10", "activity": "acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+).", "evidence": [ { "id": "Q2KIE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIE6" } ] }, { "ec_number": "2.3.3.10", "activity": "", "evidence": [ { "id": "Q2KIE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIE6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P2A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" }, { "id": "PF08540", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08540" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Hydroxymethylglutaryl-coenzyme A synthase C-terminal", "eco_id": "ECO_0000259", "start_pos": 187, "end_pos": 469, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P2A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A2" }, { "id": "PF01154", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01154" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Hydroxymethylglutaryl-coenzyme A synthase N-terminal", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 186, "start_aa": "Trp", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.3.10", "ec_name": "acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+).", "evidence": [ { "id": "2.3.3.10", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.3.10" }, { "id": "2.3.3.10", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.3.10" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 393 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P0X3-1", "uniprot_ac": "A0ABI0P0X3", "uniprot_id": "A0ABI0P0X3_BOVIN", "mass": { "chemical_mass": 38850.0, "monoisotopic_mass": 38850.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000048283", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048283", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030616", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030616", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NSHAFDE", "url": "https://omabrowser.org/oma/group/NSHAFDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24350", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24350", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0X3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZK9", "url": "https://www.uniprot.org/uniprotkb/G3MZK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZK9-1", "url": "https://www.uniprot.org/uniprotkb/G3MZK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEAHPECSPAWIPSSTRLRKALFSPPSLVKSHRKAARKSSRGQPAGERTRQRGLFSFSPLRRHYTIADFEIRGPLGKGNFGNVYMACHFIVALKVLFKSQIEKEGLEYQLRREIDIQAHLQRTHNILHLYNYFHDARRVYLILEYAPRGELYKELQNSHAFDEPRTATVMEELADALTYCHEKKVIHRNMKPEKLLLGLMGEVKMADFGWSVRKKMCGTLDYLPPEMIEGRIYNEKVDLWCLGVLCYELLVGNPPFESTSHSETYRHILKVDVRFPASIPLRAWDLISRLLRYQPSEQQPLAQVLKHPWVRAHSRRVLPPAAQMASLALSTPILL", "length": 336, "header": "tr|A0ABI0P0X3-1|A0ABI0P0X3_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P0X3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P0X3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3/entry#A0ABI0P0X3-1", "sequence": { "sequence": "MEEAHPECSPAWIPSSTRLRKALFSPPSLVKSHRKAARKSSRGQPAGERTRQRGLFSFSPLRRHYTIADFEIRGPLGKGNFGNVYMACHFIVALKVLFKSQIEKEGLEYQLRREIDIQAHLQRTHNILHLYNYFHDARRVYLILEYAPRGELYKELQNSHAFDEPRTATVMEELADALTYCHEKKVIHRNMKPEKLLLGLMGEVKMADFGWSVRKKMCGTLDYLPPEMIEGRIYNEKVDLWCLGVLCYELLVGNPPFESTSHSETYRHILKVDVRFPASIPLRAWDLISRLLRYQPSEQQPLAQVLKHPWVRAHSRRVLPPAAQMASLALSTPILL", "length": 336, "header": "tr|A0ABI0P0X3-1|A0ABI0P0X3_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P0X3-1" }, "locus": { "chromosome": "18", "start_pos": 56539535, "end_pos": 56536520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141870.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141870.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104212.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104212.1" } ] } }, { "isoform_ac": "G3MZK9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3/entry#G3MZK9-1", "sequence": { "sequence": "MGPSTPIVRHYTIADFEIRGPLGKGNFGNVYMACHFIVALKVLFKSQIEKEGLEYQLRREIDIQAHLQRTHNILHLYNYFHDARRVYLILEYAPRGELYKELQNSHAFDEPRTATVMEELADALTYCHEKKVIHRNMKPEKLLLGLMGEVKMADFGWSVRKKMCGTLDYLPPEMIEGRIYNEKVDLWCLGVLCYELLVGNPPFESTSHSETYRHILKVDVRFPASIPLRAWDLISRLLRYQPSEQQPLAQVLKHPWVRAHSRRVLPPAAQMASLALSTPILL", "length": 282, "header": "tr|G3MZK9-1|A0ABI0P0X3_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=A0ABI0P0X3-1" }, "locus": { "chromosome": "18", "start_pos": 56539535, "end_pos": 56536784, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063423.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063423.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055009.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055009.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "pmid": "" }, { "name": "chromosome passenger complex", "id": "GO:0032133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032133", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0X3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLF0" } ] } ] }, { "uniprot_ac": "A0A3Q1LLH8", "gene_name": "CDK15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LLH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LM61", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LU59", "gene_name": "MAPK15", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": "Q3T0P6", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3T0P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0P6" } ] } ] }, { "uniprot_ac": "Q4TVR5", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q4TVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4TVR5" } ] } ] }, { "uniprot_ac": "Q58D94", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q58D94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58D94" } ] } ] }, { "uniprot_ac": "Q5E9L6", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9L6" } ] } ] }, { "uniprot_ac": "Q5E9X2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q5E9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9X2" } ] } ] }, { "uniprot_ac": "Q5E9Y0", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5E9Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y0" } ] } ] }, { "uniprot_ac": "Q5E9Y9", "gene_name": "NME7", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5E9Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9Y9" } ] } ] }, { "uniprot_ac": "Q5EAB2", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5EAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAB2" } ] } ] }, { "uniprot_ac": "Q6TJY3", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6TJY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6TJY3" } ] } ] }, { "uniprot_ac": "Q7YRC6", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7YRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRC6" } ] } ] }, { "uniprot_ac": "Q8MIT6", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q8MIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MIT6" } ] } ] }, { "uniprot_ac": "Q95KV0", "gene_name": "IKBKB", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q95KV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95KV0" } ] } ] }, { "uniprot_ac": "Q9N0P9", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9N0P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9N0P9" } ] } ] }, { "uniprot_ac": "V6F977", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "V6F977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/V6F977" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 311, "start_aa": "Phe", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P0S7-1", "uniprot_ac": "A0ABI0P0S7", "uniprot_id": "A0ABI0P0S7_BOVIN", "mass": { "chemical_mass": 127533.0, "monoisotopic_mass": 127533.0 }, "refseq": { "ac": "XP_002691521", "name": "structural maintenance of chromosomes protein 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691521" }, "gene_names": [ { "name": "SMC6", "type": "recommended", "evidence": [ { "id": "A0ABI0P0S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ] }, { "name": "SMC6", "type": "synonym", "evidence": [ { "id": "XP_002691521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691521" } ] } ], "protein_names": [ { "name": "Structural maintenance of chromosomes protein 6", "type": "recommended", "evidence": [ { "id": "A0ABI0P0S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7/entry#names_and_taxonomy" } ] }, { "name": "structural maintenance of chromosomes protein 6", "type": "synonym", "evidence": [ { "id": "XP_002691521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691521" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SMC6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7", "locus": { "chromosome": "11", "start_pos": 80926302, "end_pos": 80851894, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018256", "url": "https://www.ensembl.org/id/ENSBTAG00000018256" } ] } } ], "crossref": [ { "id": "ENSBTAG00000018256", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018256", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "510381", "url": "https://www.ncbi.nlm.nih.gov/gene/510381", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:510381", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510381", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1N6G1", "url": "https://www.orthodb.org/?gene=A0A3Q1N6G1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BFH7", "url": "https://www.orthodb.org/?gene=E1BFH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19306", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19306", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19306:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19306:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13476", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13476", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3108214", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3108214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002691521", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691521", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1N6G1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N6G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N6G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N6G1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8Z4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0S7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFH7", "url": "https://www.uniprot.org/uniprotkb/E1BFH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BFH7-1", "url": "https://www.uniprot.org/uniprotkb/E1BFH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKRKEENFFSPENAKRPRQEELDDFDKDECDEDECAVSFTNGTSTLTAAEVGIIESIQLKNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGKAITTNRGSSLKGFVKDGQNSADISITIRNRGDDAYRGNVYGDTIIVQQHISMDGSRSYKLKSATGAVISTKKEELIGILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLSELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEDRAARLERKTEEQQVRLNEAEKKYKDIQDKLEKISQETSARAPECMALKADLTSKKRAYNEAEVLYNRSLNEYKALKKDDEQLCRRIEELKKSADQSLEPERLERQKKISWLKERIKALQDQESSVNQEIEQFQQAIEKDKEEHTRIKREELDVKTTLNFNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRGHFTYKPVGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQALMKKFYSPGTSRPQIIVSEFRNEMYDVRHRAAYHPEYPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSEYTRPKFLSRDVDSEISDLEDEVENKKAQILNLQQHLSTLQKDIKCNEELLRRYQLHYKELKMKIRKSISEIRELENIEEHQSVDIATLEDEAQENKIKMKMVEKNMEQQKENMEHLKSLKVEAENKYDEIKQKINQLSELADPLKDELNLADSEVDNQKRGKRHYEDKQKEHLDTLNKKKRELDMKEKELEEKMSQARQICPERIEVKKSASILDKEINRLRQKIQAEHASYGDREEIMKQYQEARESYLDLDSKVKTLKRFIKLLEEIMIHRYKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLTISVQPGEGNKAAFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVSQEDDDDRS", "length": 1098, "header": "tr|A0ABI0P0S7-1|A0ABI0P0S7_BOVIN Isoform 1 of Structural maintenance of chromosomes protein 6 OS=Bos taurus OX=9913 GN=SMC6 PE=3 SV=1 CANONICAL=A0ABI0P0S7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N6G1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7/entry#A0A3Q1N6G1-1", "sequence": { "sequence": "MAKRKEENFFSPENAKRPRQEELDDFDKDECDEDECAVSFTNGTSTLTAAEVGIIESIQLKNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGKAITTNRGSSLKGFVKDGQNSADISITIRNRGDDAYRGNVYGDTIIVQQHISMDGSRSYKLKSATGAVISTKKEELIGILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLSELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEDRAARLERKTEEQQVLYNRSLNEYKALKKDDEQLCRRIEELKKSADQSLEPERLERQKKISWLKERIKALQDQESSVNQEIEQFQQAIEKDKEEHTRIKREELDVKTTLNFNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRGHFTYKPVGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQALMKKFYSPGTSRPQIIVSEFRNEMYDVRHRAAYHPEYPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSEYTRPKFLSRDVDSEISDLEDEVENKKAQILNLQQHLSTLQKDIKCNEELLRRYQLHYKELKMKIRKSISEIRELENIEEHQSVDIATLEDEAQENKIKMKMVEKNMEQQKENMEHLKSLKVEAENKYDEIKQKINQLSELADPLKDELNLADSEVDNQKRGKRHYEDKQKEHLDTLNKKKRELDMKEKELEEKMSQARQICPERIEVKKSASILDKEINRLRQKIQAEHASYGDREEIMKQYQEARESYLDLDSKVKTLKRFIKLLEEIMIHRYKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLTISVQPGEGNKAAFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVSQEDDDDRS", "length": 1049, "header": "tr|A0A3Q1N6G1-1|A0ABI0P0S7_BOVIN Computationally mapped isoform of Structural maintenance of chromosomes protein 6 OS=Bos taurus OX=9913 GN=SMC6 PE=3 SV=1 CANONICAL=A0ABI0P0S7-1" }, "locus": { "chromosome": "11", "start_pos": 80925298, "end_pos": 80863442, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075232.3", "url": "https://www.ensembl.org/id/ENSBTAT00000075232.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066053.1", "url": "https://www.ensembl.org/id/ENSBTAP00000066053.1" } ] } }, { "isoform_ac": "A0AAA9T8Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7/entry#A0AAA9T8Z4-1", "sequence": { "sequence": "MPKDQDKKNWTILIKMNVMKMNVQFLSLMVPLLCSADISITIRNRGDDAYRGNVYGDTIIVQQHISMDGSRSYKLKSATGAVISTKKEELIGILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLSELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEDRAARLERKTEEQQVRLNEAEKKYKDIQDKLEKISQETSARAPECMALKADLTSKKRAYNEAEVLYNRSLNEYKALKKDDEQLCRRIEELKKSADQSLEPERLERQKKISWLKERIKALQDQESSVNQEIEQFQQAIEKDKEEHTRIKREELDVKTTLNFNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRGHFTYKPVGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQALMKKFYSPGTSRPQIIVSEFRNEMYDVRHRAAYHPEYPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSEYTRPKFLSRDVDSEISDLEDEVENKKAQILNLQQHLSTLQKDIKCNEELLRRYQLHYKELKMKIRKSISEIRELENIEEHQSVDIATLEDEAQENKIKMKMVEKNMEQQKENMEHLKSLKVEAENKYDEIKQKINQLSELADPLKDELNLADSEVDNQKRGKRHYEDKQKEHLDTLNKKKRELDMKEKELEEKMSQARQICPERIEVKKSASILDKEINRLRQKIQAEHASYGDREEIMKQYQEARESYLDLDSKVKTLKRFIKLLEEIMIHRYKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLTISVQPGEGNKAAFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVSQEDDDDRS", "length": 1010, "header": "tr|A0AAA9T8Z4-1|A0ABI0P0S7_BOVIN Computationally mapped isoform of Structural maintenance of chromosomes protein 6 OS=Bos taurus OX=9913 GN=SMC6 PE=3 SV=1 CANONICAL=A0ABI0P0S7-1" }, "locus": { "chromosome": "11", "start_pos": 80925298, "end_pos": 80863482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122246.2", "url": "https://www.ensembl.org/id/ENSBTAT00000122246.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093310.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093310.1" } ] } }, { "isoform_ac": "A0ABI0P0S7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7/entry#A0ABI0P0S7-1", "sequence": { "sequence": "MAKRKEENFFSPENAKRPRQEELDDFDKDECDEDECAVSFTNGTSTLTAAEVGIIESIQLKNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGKAITTNRGSSLKGFVKDGQNSADISITIRNRGDDAYRGNVYGDTIIVQQHISMDGSRSYKLKSATGAVISTKKEELIGILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLSELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEDRAARLERKTEEQQVRLNEAEKKYKDIQDKLEKISQETSARAPECMALKADLTSKKRAYNEAEVLYNRSLNEYKALKKDDEQLCRRIEELKKSADQSLEPERLERQKKISWLKERIKALQDQESSVNQEIEQFQQAIEKDKEEHTRIKREELDVKTTLNFNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRGHFTYKPVGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQALMKKFYSPGTSRPQIIVSEFRNEMYDVRHRAAYHPEYPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSEYTRPKFLSRDVDSEISDLEDEVENKKAQILNLQQHLSTLQKDIKCNEELLRRYQLHYKELKMKIRKSISEIRELENIEEHQSVDIATLEDEAQENKIKMKMVEKNMEQQKENMEHLKSLKVEAENKYDEIKQKINQLSELADPLKDELNLADSEVDNQKRGKRHYEDKQKEHLDTLNKKKRELDMKEKELEEKMSQARQICPERIEVKKSASILDKEINRLRQKIQAEHASYGDREEIMKQYQEARESYLDLDSKVKTLKRFIKLLEEIMIHRYKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLTISVQPGEGNKAAFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVSQEDDDDRS", 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"MAKRKEENFFSPENAKRPRQEELDDFDKDECDEDECAVSFTNGTSTLTAAEVGIIESIQLKNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGKAITTNRGSSLKGFVKDGQNSADISITIRNRGDDAYRGNVYGDTIIVQQHISMDGSRSYKLKSATGAVISTKKEELIGILDHFNIQFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLSELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEDRAARLERKTEEQQVRLNEAEKKYKDIQDKLEKISQETSARAPECMALKADLTSKKRAYNEAEVLYNRSLNEYKALKKDDEQLCRRIEELKKSADQSLEPERLERQKKISWLKERIKALQDQESSVNQEIEQFQQAIEKDKEEHTRIKREELDVKTTLNFNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRGHFTYKPVGPLGACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQALMKKFYSPGTSRPQIIVSEFRNEMYDVRHRAAYHPEYPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSEYTRPKFLSRDVDSEISDLEDEVENKKAQILNLQQHLSTLQKDIKCNEELLRRYQLHYKELKMKIRKSISEIRELENIEEHQSVDIATLEDEAQENKIKMKMVEKNMEQQKENMEHLKSLKVEAENKYDEIKQKINQLSELADPLKDELNLADSEVDNQKRGKRHYEDKQKEHLDTLNKKKRELDMKEKELEEKMSQARQICPERIEVKKSASILDKEINRLRQKIQAEHASYGDREEIMKQYQEARESYLDLDSKVKTLKRFIKLLEEIMIHRYKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLTISVQPGEGNKAAFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVSQEDDDDRS", "length": 1071, "header": "tr|E1BFH7-1|A0ABI0P0S7_BOVIN Computationally mapped isoform of Structural maintenance of chromosomes protein 6 OS=Bos taurus OX=9913 GN=SMC6 PE=3 SV=3 CANONICAL=A0ABI0P0S7-1" }, "locus": { "chromosome": "11", "start_pos": 80925298, "end_pos": 80863442, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024303.8", "url": "https://www.ensembl.org/id/ENSBTAT00000024303.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024303.7", "url": "https://www.ensembl.org/id/ENSBTAP00000024303.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:510381", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510381", "resource": "KEGG Pathway" }, { "id": "R-BTA-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" }, { "name": "Smc5-Smc6 complex", "id": "GO:0030915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030915", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0S7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" }, { "start_pos": 971, "end_pos": 973, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P0S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0S7" }, { "id": "PF13476", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13476" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rad50/SbcC-type AAA", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 264, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": "" } ], 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"categories": [ "Protein Classification" ] }, { "id": "MFYNDVE", "url": "https://omabrowser.org/oma/group/MFYNDVE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12418", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12418", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12418:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12418:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-165158", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-165158", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-77289", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77289", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "16645", "url": "https://www.rhea-db.org/rhea/16645", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "30135", "url": "https://www.rhea-db.org/rhea/30135", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "30143", "url": "https://www.rhea-db.org/rhea/30143", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40059", "url": "https://www.rhea-db.org/rhea/40059", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40119", "url": "https://www.rhea-db.org/rhea/40119", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40139", "url": "https://www.rhea-db.org/rhea/40139", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40151", "url": "https://www.rhea-db.org/rhea/40151", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0P2S3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2S3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG28", "url": "https://www.uniprot.org/uniprotkb/E1BG28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BG28-1", "url": "https://www.uniprot.org/uniprotkb/E1BG28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRSCTAGLRSIWALRGRREGAPRLSMDLQPARRLFSTEKVIHKDWALPNPSWSKDLKLLFDQFMKKCEDGSWERLPSYKRRSTQESEDFKTYFLGSALQTQSLWKKAQLFTRGFEDGLGFEYVIFKNNDEKRTVCLFQGGPYLQGVPGLLHGGAMATMIDIALGSCTGGAVMTANLNINFKRPVPLCSVVVINSQLDKLEGRKLFLSCNVRSVDEKTLYSEATGLFIKLDPEKSST", "length": 237, "header": "tr|A0ABI0P2S3-1|A0ABI0P2S3_BOVIN Isoform 1 of Acyl-coenzyme A thioesterase THEM4 OS=Bos taurus OX=9913 GN=THEM4 PE=3 SV=1 CANONICAL=A0ABI0P2S3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P2S3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3/entry#A0ABI0P2S3-1", "sequence": { "sequence": "MLRSCTAGLRSIWALRGRREGAPRLSMDLQPARRLFSTEKVIHKDWALPNPSWSKDLKLLFDQFMKKCEDGSWERLPSYKRRSTQESEDFKTYFLGSALQTQSLWKKAQLFTRGFEDGLGFEYVIFKNNDEKRTVCLFQGGPYLQGVPGLLHGGAMATMIDIALGSCTGGAVMTANLNINFKRPVPLCSVVVINSQLDKLEGRKLFLSCNVRSVDEKTLYSEATGLFIKLDPEKSST", "length": 237, "header": "tr|A0ABI0P2S3-1|A0ABI0P2S3_BOVIN Isoform 1 of Acyl-coenzyme A thioesterase THEM4 OS=Bos taurus OX=9913 GN=THEM4 PE=3 SV=1 CANONICAL=A0ABI0P2S3-1" }, "locus": { "chromosome": "3", "start_pos": 18892921, "end_pos": 18844273, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136349.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136349.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105711.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105711.1" } ] } }, { "isoform_ac": "E1BG28-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3/entry#E1BG28-1", "sequence": { "sequence": "MLRSCTAGLRSIWALRGRREGAPRLSMDLQPARRLFSTEKVIHKDWALPNPSWSKDLKLLFDQFMKKCEDGSWERLPSYKRRSTQESEDFKTYFLDPKLVEEAQLFTRGFEDGLGFEYVIFKNNDEKRTVCLFQGGPYLQGVPGLLHGGAMATMIDIALGSCTGGAVMTANLNINFKRPVPLCSVVVINSQLDKLEGRKLFLSCNVRSVDEKTLYSEATGLFIKLDPEKSST", "length": 232, "header": "tr|E1BG28-1|A0ABI0P2S3_BOVIN Computationally mapped isoform of Acyl-coenzyme A thioesterase THEM4 OS=Bos taurus OX=9913 GN=THEM4 PE=3 SV=3 CANONICAL=A0ABI0P2S3-1" }, "locus": { "chromosome": "3", "start_pos": 18892921, "end_pos": 18844273, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046523.5", "url": "https://www.ensembl.org/id/ENSBTAT00000046523.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043816.4", "url": "https://www.ensembl.org/id/ENSBTAP00000043816.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-165158", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-165158", "resource": "Reactome", "description": "Activation of AKT2" }, { "id": "R-BTA-77289", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77289", "resource": "Reactome", "description": "Mitochondrial Fatty Acid Beta-Oxidation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IG10-1", "protein_name": "Acyl-coenzyme A thioesterase THEM4", "gene_name": "Them4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLRSCAARLRTLVAAPARRPGPVWRLFSSEKVVHKDYGLPNPSWSKDLRLLFDQFMKKCEDGSWKRLSSYRQNPTRVLKDFQTRFVDPRFMKEEQMSKAQQFTRSFEEGLGFEYVMFYNKVERRMVCLFQSGLHLQGVPGYVHGGAIATIIDVTTGMCAYAEGVAMTANLNIDYKKPIPLCSVVVVNCQISNTEGRKLFVSCSIQSVDEKTLYTEATALFVKLDPDKRLT", "length": 230 }, "evidence": [ { "id": "A0ABI0P2S3", "url": "https://omabrowser.org/oma/group/A0ABI0P2S3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V1AEQ0-1", "protein_name": "Acyl-coenzyme A thioesterase THEM4", "gene_name": "THEM4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSQPWEPGDTRGPLMGGRGGRGQRGLGPVIQTLNVPSGDSVPQLRHQSPGVTTAVPVPTPHGATAAPHPTATTDCVPTAPLTPSPVCCCVSPQALCSVSPQDLAVPNTGWSAAMCEQFQRLLRRAADGSWRRIPSYRRGLDYLPEVVQMAVGVVTRPGPRLFLRSVDEEGAGFEYAIFLHASGHRTQCLCQLGPYLEGHHGFAHGGAIATLIDSTVGTCALAVAKASVMTAKLSISYLAPVPVGAVVVADSRMERHEGRKIFLSCHVRDTKRDTLYAEATGEDMWCCGDGAGDTETIPQNCASG", "length": 304 }, "evidence": [ { "id": "A0ABI0P2S3", "url": "https://omabrowser.org/oma/group/A0ABI0P2S3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q3UUI3-1", "protein_name": "Acyl-coenzyme A thioesterase THEM4", "gene_name": "Them4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRNCAMRLRTLGATPARRPGAARRLFSSEKVIRKDYALPNPSWTKDLRLLFDQFMKKCEDGSWKRMPSHRQNPTRAIQEFQTLFVDSKFKKEEQMSKAQQFTRSFEEGLGFEYAMFYNKVEKRTVSLFQGGLHLQGVPGFVHGGAIATIIDVTTGTCAISEGVAMTANLNITYKKPIPLLSVVVVNSQLQKIEGRKLFVSCTIQSIDEKTLYTEATALFIKLDPEKPLT", "length": 230 }, "evidence": [ { "id": "A0ABI0P2S3", "url": "https://omabrowser.org/oma/group/A0ABI0P2S3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q566R0-1", "protein_name": "Acyl-coenzyme A thioesterase THEM4", "gene_name": "Them4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRSCAMRLRTLGATPARRPEATRRLFSSEEVVCKDYALPNPSWTKDLRLLFDQFMKKCEDGSWKRLPSYRQNPPQALQEFQTHFVDSKFKKEEQMSKAQQFTRSLEEGLGFEYAMFYNKAEKRIVCLFQGGLHLQGMPGFVHGGAIATIIDITAGMCAFSEGIVMTANLNIDYKKPIPLLSVVVVNSQLQKIEGRKLFVSCTIQSTDEKTLHTQATALFIKLDPDKPLT", "length": 230 }, "evidence": [ { "id": "A0ABI0P2S3", "url": "https://omabrowser.org/oma/group/A0ABI0P2S3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5T1C6-1", "protein_name": "Acyl-coenzyme A thioesterase THEM4", "gene_name": "THEM4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRSCAARLRTLGALCLPPVGRRLPGSEPRPELRSFSSEEVILKDCSVPNPSWNKDLRLLFDQFMKKCEDGSWKRLPSYKRTPTEWIQDFKTHFLDPKLMKEEQMSQAQLFTRSFDDGLGFEYVMFYNDIEKRMVCLFQGGPYLEGPPGFIHGGAIATMIDATVGMCAMMAGGIVMTANLNINYKRPIPLCSVVMINSQLDKVEGRKFFVSCNVQSVDEKTLYSEATSLFIKLNPAKSLT", "length": 240 }, "evidence": [ { "id": "A0ABI0P2S3", "url": "https://omabrowser.org/oma/group/A0ABI0P2S3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2S3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2S3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2S3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2S3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2S3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ], "pmid": "" }, { "name": "regulation of mitochondrial membrane permeability involved in apoptotic process", "id": "GO:1902108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902108", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2S3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2S3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "long-chain fatty acyl-CoA hydrolase activity", "id": "GO:0052816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052816", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2S3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2S3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16645", "name": "", "equation": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "A5PJT0-1", "Q3T0R7-1", "A0ABI0P2S3-1", "Q3SWX2-1", "P45478-1", "F6RWU6-1", "A0A3Q1M171-1", "F6QGE6-1", "Q1JQA0-1", "A0AAA9T509-1", "E1BB89-1", "A0AAA9SCF5-1" ], "evidence": [ { "id": "16645", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16645" } ] }, { "id": "30135", "name": "", "equation": "dodecanoyl-CoA + H2O = dodecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "A5PJT0-1", "Q3T0R7-1", "A0ABI0P2S3-1", "F6RWU6-1", "A0A3Q1M171-1", "F6QGE6-1", "A0AAA9T509-1" ], "evidence": [ { "id": "30135", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30135" } ] }, { "id": "30143", "name": "", "equation": "octanoyl-CoA + H2O = octanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "Q3T0R7-1", "A0ABI0P2S3-1", "Q3SWX2-1", "F6RWU6-1", "F6QGE6-1" ], "evidence": [ { "id": "30143", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30143" } ] }, { "id": "40059", "name": "", "equation": "decanoyl-CoA + H2O = decanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "Q3T0R7-1", "A0ABI0P2S3-1", "Q3SWX2-1", "F6RWU6-1", "F6QGE6-1", "A0AAA9T509-1" ], "evidence": [ { "id": "40059", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40059" } ] }, { "id": "40119", "name": "", "equation": "tetradecanoyl-CoA + H2O = tetradecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "A5PJT0-1", "Q3T0R7-1", "A0ABI0P2S3-1", "Q3SWX2-1", "F6RWU6-1", "A0A3Q1M171-1", "F6QGE6-1", "A0AAA9T509-1" ], "evidence": [ { "id": "40119", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40119" } ] }, { "id": "40139", "name": "", "equation": "(9Z)-octadecenoyl-CoA + H2O = (9Z)-octadecenoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "A0ABI0P2S3-1", "F6RWU6-1", "F6QGE6-1" ], "evidence": [ { "id": "40139", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40139" } ] }, { "id": "40151", "name": "", "equation": "(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "A0ABI0P2S3-1", "F6RWU6-1" ], "evidence": [ { "id": "40151", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40151" } ] }, { "id": "R-BTA-109700", "name": "AKT2 binds PIP3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1NH21-1", "A0ABI0P2S3-1" ], "evidence": [ { "id": "R-BTA-109700", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-109700" } ] }, { "id": "R-BTA-5690066", "name": "ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P2S3-1", "Q3SWX2-1" ], "evidence": [ { "id": "R-BTA-5690066", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5690066" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1M171", "gene_name": "ACOT11", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A3Q1M171", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M171" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A3Q1M171", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M171" } ] } ] }, { "uniprot_ac": "A0A3Q1NH21", "gene_name": "AKT2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NH21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NH21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NH21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NH21" } ] } ] }, { "uniprot_ac": "A0AAA9SCF5", "gene_name": "PPT1", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0AAA9SCF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF5" } ] }, { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0AAA9SCF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF5" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0AAA9SCF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF5" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0AAA9SCF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF5" } ] } ] }, { "uniprot_ac": "A0AAA9T509", "gene_name": "OLAH", "activity": [ { "ec_number": "3.1.2.14", "activity": "hexadecanoyl-[ACP] + H2O = hexadecanoate + holo-[ACP] + H(+).", "evidence": [ { "id": "A0AAA9T509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T509" } ] }, { "ec_number": "3.1.2.14", "activity": "", "evidence": [ { "id": "A0AAA9T509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T509" } ] } ] }, { "uniprot_ac": "A0ABI0P2S3", "gene_name": "THEM4", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0ABI0P2S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0ABI0P2S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ] } ] }, { "uniprot_ac": "A1A4L1", "gene_name": "THEM4", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A1A4L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4L1" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A1A4L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4L1" } ] } ] }, { "uniprot_ac": "A5PJT0", "gene_name": "MBLAC2", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A5PJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJT0" } ] }, { "ec_number": "3.5.2.6", "activity": "a beta-lactam + H2O = a substituted beta-amino acid.", "evidence": [ { "id": "A5PJT0", "database": "UniProtKB", "url": 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"RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSL5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5C4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGV3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGV3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2V6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2V6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADTAPNGPQGAGAVQFMMANKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKILDAKDSNSLPLLRSLLDKLSANQQNILKFIACNEIFLMPATVFMLFSGQGSLFQPFIYYRFLTLRYSSRRNPYCRTLFNELRIVVEHLIMKPACPLFVRRLCLQSIAFISRLAPTVA", "length": 247, "header": "tr|A0ABI0P2V6-1|A0ABI0P2V6_BOVIN Isoform 1 of Transmembrane protein 33 OS=Bos taurus OX=9913 GN=TMEM33 PE=3 SV=1 CANONICAL=A0ABI0P2V6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LSL5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V6/entry#A0A3Q1LSL5-1", "sequence": { "sequence": "MADTAPNGPQGAGAVQFMMANKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKILDAKDSNSLPLLRSLLDKLSANQQNILKFIACNEIFLMPATVFMLFSGQGSLFQPFIYYRFLTLRYSSRRNPYCRRKRQPTPVFLPGESQGQGSLVG", "length": 227, "header": "tr|A0A3Q1LSL5-1|A0ABI0P2V6_BOVIN Computationally mapped isoform of Transmembrane protein 33 OS=Bos taurus OX=9913 GN=TMEM33 PE=3 SV=1 CANONICAL=A0ABI0P2V6-1" }, "locus": { "chromosome": "6", "start_pos": 60835079, "end_pos": 60815109, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076565.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076565.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060250.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060250.2" } ] } }, { "isoform_ac": "A0A3Q1M5C4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V6/entry#A0A3Q1M5C4-1", "sequence": { "sequence": "QQFMMANKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKILDAKDSNSLPLLRSLLDKLSANQQNILKFIACNEIFLMPATVFMLFSGQGSLFQPFIYYRFLTLRYSSRRNPYCRTLFNELRIVVEHLIMKPACPLFVRRLCLQSIAFISRLAPTVA", "length": 233, "header": "tr|A0A3Q1M5C4-1|A0ABI0P2V6_BOVIN Computationally mapped isoform of Transmembrane protein 33 OS=Bos taurus OX=9913 GN=TMEM33 PE=3 SV=2 CANONICAL=A0ABI0P2V6-1" }, "locus": { "chromosome": "6", "start_pos": 60829119, "end_pos": 60817466, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073147.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073147.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065097.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065097.2" } ] } }, { "isoform_ac": "A0AAA9TGV3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V6/entry#A0AAA9TGV3-1", "sequence": { "sequence": "MQFMMANKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKILDAKDSNSLPLLRSLLDKLSANQQNILKFIACNEIFLMPATVFMLFSGQGSLFQPFIYYRFLTLRYSSRRNPYCRTLFNELRIVVEHLIMKPACPLFVRRLCLQSIAFISRLAPTVA", "length": 233, "header": "tr|A0AAA9TGV3-1|A0ABI0P2V6_BOVIN Computationally mapped isoform of Transmembrane protein 33 OS=Bos taurus OX=9913 GN=TMEM33 PE=3 SV=1 CANONICAL=A0ABI0P2V6-1" }, "locus": { "chromosome": "6", "start_pos": 60829119, "end_pos": 60816298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126538.2", "url": "https://www.ensembl.org/id/ENSBTAT00000126538.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096279.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096279.1" } ] } }, { "isoform_ac": "A0ABI0P2V6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V6/entry#A0ABI0P2V6-1", "sequence": { "sequence": "MADTAPNGPQGAGAVQFMMANKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKILDAKDSNSLPLLRSLLDKLSANQQNILKFIACNEIFLMPATVFMLFSGQGSLFQPFIYYRFLTLRYSSRRNPYCRTLFNELRIVVEHLIMKPACPLFVRRLCLQSIAFISRLAPTVA", "length": 247, "header": "tr|A0ABI0P2V6-1|A0ABI0P2V6_BOVIN Isoform 1 of Transmembrane protein 33 OS=Bos taurus OX=9913 GN=TMEM33 PE=3 SV=1 CANONICAL=A0ABI0P2V6-1" }, "locus": { "chromosome": "6", "start_pos": 60829119, "end_pos": 60815109, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149383.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149383.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104824.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104824.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614879", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614879", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UR13-1", "protein_name": "Transmembrane protein 33", "gene_name": "TMEM33", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADTAPNGPQGGAVQFMMANKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKVLDAKGSNSLPLLRSVLDKLSANQQNILKFIACNEIFLMPATVFMLFSGQGSLLQPFIYYRFLTLRYSSRRNPYCRTLFNELRIVVEHLIMKPACPLFVRRLCLQSIAFISRLAPTVA", "length": 246 }, "evidence": [ { "id": "A0ABI0P2V6", "url": "https://omabrowser.org/oma/group/A0ABI0P2V6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F2X2-1", "protein_name": "Transmembrane protein 33 isoform X1", "gene_name": "Tmem33", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADTTPNGPQGAGAVQFMMTNKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKVLDAKGSNSLPLLRSVLDKLSANQQNILKFIACNEIFLMPATVFMLFSGQGSLLQPFIYYRFLTLRYSSRRNPYCRNLFNELRIVVEHIIMKPSCPLFVRRLCLQSIAFISRLAPTVA", "length": 247 }, "evidence": [ { "id": "A0ABI0P2V6", "url": "https://omabrowser.org/oma/group/A0ABI0P2V6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P57088-1", "protein_name": "Transmembrane protein 33", "gene_name": "TMEM33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADTTPNGPQGAGAVQFMMTNKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKVLDARGSNSLPLLRSVLDKLSANQQNILKFIACNEIFLMPATVFMLFSGQGSLLQPFIYYRFLTLRYSSRRNPYCRTLFNELRIVVEHIIMKPACPLFVRRLCLQSIAFISRLAPTVP", "length": 247 }, "evidence": [ { "id": "A0ABI0P2V6", "url": "https://omabrowser.org/oma/group/A0ABI0P2V6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CR67-1", "protein_name": "Transmembrane protein 33", "gene_name": "Tmem33", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTTPNGPQGAGAVQFMMTNKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKVLDAKGSNSLPLLRSFLDKLSTNQQNILKFIACNEIFLMPATVFMLFSGQGSLLQPFIYYRFLTLRYSSRRNPYCRNLFNELRIVVEHIIMKPSCPLFVRRLCLQSIAFISRLAPTVA", "length": 247 }, "evidence": [ { "id": "A0ABI0P2V6", "url": "https://omabrowser.org/oma/group/A0ABI0P2V6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V447-1", "protein_name": "Krueppel homolog 2", "gene_name": "Kr-h2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSAPTDQPPRSEGAQTNSSERSSQQQEQPQQSQSQNVPAKLLQHFQTNRIDSALWALRLLVIFFTVSYVLPIFTSQQSAFSKVMLANAAISALRLHQRLPAFAFSREFLARLFAEDSCHYMMYSLIFFNIRPSLLVLIPVLLYSVLHASSYSLKLLDLIGQNSWWGARFIISIVEFQAANILKATAFCEIFIMPYAIVLAFMNHAGLMTPVIYYHYLVMRYSSRRNPYPRNAFAELRITFEALAARSPPAFAKIIRGGIGFVNRLAPQLQPAAAQE", "length": 276 }, "evidence": [ { "id": "A0ABI0P2V6", "url": "https://omabrowser.org/oma/group/A0ABI0P2V6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z142-1", "protein_name": "Transmembrane protein 33", "gene_name": "Tmem33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADTTPNGPQGAGAVQFMMTNKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKVLDAKGSNSLPLLRSVLDKLSTNQQNILKFIACNEIFLMPATVFMLFSGQGSLLQPFIYYRFLTLRYSSRRNPYCRNLFNELRIVVEHIIMKPSCPLFVRRLCLQSIAFISRLAPTVA", "length": 247 }, "evidence": [ { "id": "A0ABI0P2V6", "url": "https://omabrowser.org/oma/group/A0ABI0P2V6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2V6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V6" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2V6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum tubular network organization", "id": "GO:0071786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071786", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2V6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V6" } ], "pmid": "" }, { "name": "membrane organization", "id": "GO:0061024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061024", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2V6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P0I8-1", "uniprot_ac": "A0ABI0P0I8", "uniprot_id": "A0ABI0P0I8_BOVIN", "mass": { "chemical_mass": 184946.0, "monoisotopic_mass": 184946.0 }, "refseq": { "ac": "XP_024850598", "name": "protein Wiz isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850598" }, "gene_names": [ { "name": "WIZ", "type": "recommended", "evidence": [ { "id": "A0ABI0P0I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8" } ] }, { "name": "WIZ", "type": "synonym", "evidence": [ { "id": "XP_024850598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850598" } ] } ], "protein_names": [ { "name": "Protein Wiz", "type": "recommended", "evidence": [ { "id": "A0ABI0P0I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8/entry#names_and_taxonomy" } ] }, { "name": "Widely-interspaced zinc finger-containing protein", "type": "synonym", "evidence": [ { "id": "A0ABI0P0I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8/entry#names_and_taxonomy" } ] }, { "name": "protein Wiz isoform X4", "type": "synonym", "evidence": [ { "id": "XP_024850598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850598" } ] } ], "function": [ { "annotation": "May link EHMT1 and EHMT2 histone methyltransferases to the CTBP corepressor machinery. May be involved in EHMT1-EHMT2 heterodimer formation and stabilization.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0NS70", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS70#function" }, { "database": "UniProtKB", "id": "ARBA00057825", "url": "https://www.uniprot.org/uniprotkb/ARBA00057825#function" }, { "database": "UniProtKB", "id": "A0ABI0P0I8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8#function" }, { "database": "UniProtKB", "id": "F1MLJ0", "url": "https://www.uniprot.org/uniprotkb/F1MLJ0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0I8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "WIZ", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8", "locus": { "chromosome": "7", "start_pos": 7731339, "end_pos": 7720134, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010450", "url": "https://www.ensembl.org/id/ENSBTAG00000010450" } ] } } ], "crossref": [ { "id": "ENSBTAG00000010450", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010450", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "535200", "url": "https://www.ncbi.nlm.nih.gov/gene/535200", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MLJ0", "url": "https://www.orthodb.org/?gene=F1MLJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24396:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24396:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23015", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23015", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024850598", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024850598", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MA84", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MA84-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NIU8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NIU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NIU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NIU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5M9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5M9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS70", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS70-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0I8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0I8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MLJ0", "url": "https://www.uniprot.org/uniprotkb/F1MLJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MLJ0-1", "url": "https://www.uniprot.org/uniprotkb/F1MLJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGPLAGGLAAPDRPRGPERLPGPAPREDIEGGAEVAEGEGCIFRSTHYLPVTKEGPRDILDGRGGISDGQPHPGLSEALPRATSATHRISSCCWDGGSLDFQPGSPSPHPLGHYPGPLDGRGPWERPLIQEAGEDLASEQRFEDSVIMRTVKPHAELEGSRRFLYHHQGESKVFEKVPRGRPRFDWLQDADEAVPLQDAGLDMDLPPQPSPLTSFRTVLMPVDDTMKTLDGPVVGTREHLAGLEGLTQPSEWSLPRSASEVATQTWTVNSEASVERLQPLLSSIRTRPYLCELLEEVAEGADSPDEDEDEEPAVFPCIECSIYFKQKEHLLEHMSQHRRAPGQEPPAELAPLACGECGWAFADPGALERHRQLHQASREKIIEEIQKLKQVPGDAGREARLQCPRCVFGTNSSKAFVQHAKLHAQEPRGPAAQEPFGGSSGAGSPGPDATSLAYQPYEDPSGLSACVFCGFPAPSESLLREHVRLVHAHPHWEEEDGEAFEEEGPASRPGTSQDAYTRFSEAADYFGKAEPLLAPTWQENPAGYDPSLAFGPGCQQLGMRDFPLSKPLPQCSSQRPLGRPAFPSPLASAAYSLQASRSKNVVQPQGLPGHLEDQRHPWSEEEDEEEEEEEELLLASEMEFPPENRVFAPPASPGLIPQSALELKRTFREALQTAVASRAQQQQLCGMVPVVLVAKLGPRVMAAAARAPPRLQPEELGLGGAHPLDFLLLDTPLGGPLGLDPFLDGDPGVTLKPEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTVSPINILQELLATSAAERPPSPLCREAGVPPSGFLTSRRPRLPLTVPFPPTWAEDPGPAYGDAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDTPLGLPPSLTKKSNSPKEIVAGAPRPGLLALAKPLDAPAVNKAIKSPPGFSAKGLAHPPNSPLLKKASLALAGSPTHKNPEDKSPQLSLSPRPASPKAQWPQSEDEGPLNLTSGPEPARDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGPPNPSGPSPKALAKVVSSGGPGSSLEARSPADLHLSPLAKKLPPPPGSPLGHSPTVSPPPTARKMFPGLSSPSLPKKLKPEQMRVEIKREMLPGALHGEPHPSEGPWVAPREDMTPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKPCLIKKEPPAGDLAPALTEDGPPTVAPGPMQAPLPLAPMAGRPGKPGAGPAQIPRELTLAPITGTKHSATGYLGSVAAKRPLQEDRLLPAEVKAKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQSGRPFTKKFRSAGHGRDGDKRPPLGLAPGGLAVVGRGAGGEPGPEAGRAADSGERPLAASPPGTVKAEEHQRQNINKFERRQARPPDASAARGSEEANDLHQKLEEVRQPPPRVRPVPALVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEEWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAAEAP", "length": 1707, "header": "tr|A0ABI0P0I8-1|A0ABI0P0I8_BOVIN Isoform 1 of Protein Wiz OS=Bos taurus OX=9913 GN=WIZ PE=3 SV=1 CANONICAL=A0ABI0P0I8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MA84-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8/entry#A0A3Q1MA84-1", "sequence": { "sequence": "MAASTAQCRVTKAESKAAAGPRAGGARERAPAGAPPPGPPSPGPAALPSPPPPPPPPPPPPPSRDGPKAEPEPGLGPAPAPGLGSEENAMVAMDLGSPPLPKKSLPVPGPLEQVANRLSSKMAAEVPHGSKQELPDLKAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDTPLGLPPSLTKKSNSPKEIVAGAPRPGLLALAKPLDAPAVNKAIKSPPGFSAKGLAHPPNSPLLKKASLALAGSPTHKNPEDKSPQLSLSPRPASPKAQWPQSEDEGPLNLTLDSDGGRELDCQLCGAWFETRRGLSSHARAHLRHLGVSDPDAKGSPIDVLHGLIRRAGVQIRLPLGRGALALLGRPPPASAALSLLPPPPPAKRAKLKAKGTASPWGKQDLPAAAAAGIFWASDVEPSPLNLSSGPEPARDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGPPNPSGPSPKALAKVVSSGGPGSSLEARSPADLHLSPLAKKLPPPPGSPLGHSPTVSPPPTARKMFPGLSSPSLPKKLKPEQMRVEIKREMLPGALHGEPHPSEGPWVAPREDMTPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKPCLIKKEPPAGDLAPALTEDGPPTVAPGPMQAPLPLAPMAGRPGKPGAGPAQIPRELTLAPITGTKHSATGYLGSVAAKRPLQEDRLLPAEVKAKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQSGRPFTKKFRSAGHGRDGDKRPPLGLAPGGLAVVGRGAGGEPGPEAGRAADSGERPLAASPPGTVKAEEHQRQNINKFERRQARPPDASAARGSEEANDLHQKLEEVRQPPPRVRPVPALVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEEWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAAEAP", "length": 1057, "header": "tr|A0A3Q1MA84-1|A0ABI0P0I8_BOVIN Computationally mapped isoform of Protein Wiz OS=Bos taurus OX=9913 GN=WIZ PE=3 SV=2 CANONICAL=A0ABI0P0I8-1" }, "locus": { "chromosome": "7", "start_pos": 7730335, "end_pos": 7720716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087048.3", "url": "https://www.ensembl.org/id/ENSBTAT00000087048.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067122.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067122.2" } ] } }, { "isoform_ac": "A0A3Q1NIU8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8/entry#A0A3Q1NIU8-1", "sequence": { "sequence": "MDGPLAGGLAAPDRPRGPERLPGPAPREDIEGGAEVAEGEGCIFRSTHYLPVTKEGPRDILDGRGGISVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTVSPINILQELLATSAAERPPSPLCREAGVPPSGFLTSRRPRLPLTVPFPPTWAEDPGPAYGDASGPEPARDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGPPNPSGPSPKALAKVVSSGGPGSSLEARSPADLHLSPLAKKLPPPPGSPLGHSPTVSPPPTARKMFPGLSSPSLPKKLKPEQMRVEIKREMLPGALHGEPHPSEGPWVAPREDMTPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKPCLIKKEPPAGDLAPALTEDGPPTVAPGPMQAPLPLAPMAGRPGKPGAGPAQIPRELTLAPITGTKHSATGYLGSVAAKRPLQEDRLLPAEVKAKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQSGRPFTKKFRSAGHGRDGDKRPPLGLAPGGLAVVGRGAGGEPGPEAGRAADSGERPLAASPPGTVKAEEHQRQNINKFERRQARPPDASAARGSEEANDLHQKLEEVRQPPPRVRPVPALVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEEWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAAEAP", "length": 794, "header": "tr|A0A3Q1NIU8-1|A0ABI0P0I8_BOVIN Computationally mapped isoform of Protein Wiz OS=Bos taurus OX=9913 GN=WIZ PE=3 SV=3 CANONICAL=A0ABI0P0I8-1" }, "locus": { "chromosome": "7", "start_pos": 7730335, "end_pos": 7706828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069818.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069818.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071989.3", "url": "https://www.ensembl.org/id/ENSBTAP00000071989.3" } ] } }, { "isoform_ac": "A0AAA9T5M9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8/entry#A0AAA9T5M9-1", "sequence": { "sequence": "MDGPLAGGLAAPDRPRGPERLPGPAPREDIEGGAEVAEGEGCIFRSTHYLPVTKEGPRDILDGRGGISVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTVSPINILQELLATSAAERPPSPLCREAGVPPSGFLTSRRPRLPLTVPFPPTWAEDPGPAYGDGLGSEENAMVAMDLGSPPLPKKSLPVPGPLEQVANRLSSKMAAEVPHGSKQELPDLKAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDTPLGLPPSLTKKSNSPKEIVAGAPRPGLLALAKPLDAPAVNKAIKSPPGFSAKGLAHPPNSPLLKKASLALAGSPTHKNPEDKSPQLSLSPRPASPKAQWPQSEDEGPLNLTSGPEPARDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGPPNPSGPSPKALAKVVSSGGPGSSLEARSPADLHLSPLAKKLPPPPGSPLGHSPTVSPPPTARKMFPGLSSPSLPKKLKPEQMRVEIKREMLPGALHGEPHPSEGPWVAPREDMTPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKPCLIKKEPPAGDLAPALTEDGPPTVAPGPMQAPLPLAPMAGRPGKPGAGPAQIPRELTLAPITGTKHSATGYLGSVAAKRPLQEDRLLPAEVKAKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQSGRPFTKKFRSAGHGRDGDKRPPLGLAPGGLAVVGRGAGGEPGPEAGRAADSGERPLAASPPGTVKAEEHQRQNINKFERRQARPPDASAARGSEEANDLHQKLEEVRQPPPRVRPVPALVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEEWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAAEAP", "length": 1019, "header": "tr|A0AAA9T5M9-1|A0ABI0P0I8_BOVIN Computationally mapped isoform of Protein Wiz OS=Bos taurus OX=9913 GN=WIZ PE=3 SV=2 CANONICAL=A0ABI0P0I8-1" }, "locus": { "chromosome": "7", "start_pos": 7730335, "end_pos": 7706828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105679.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105679.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094079.2", "url": "https://www.ensembl.org/id/ENSBTAP00000094079.2" } ] } }, { "isoform_ac": "A0ABI0NS70-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8/entry#A0ABI0NS70-1", "sequence": { "sequence": "MDGPLAGGLAAPDRPRGPERLPGPAPREDIEGGAEVAEGEGCIFRSTHYLPVTKEGPRDILDGRGGISDGQPHPGLSEALPRATSATHRISSCCWDGGSLDFQPGSPSPHPLGHYPGPLDGRGPWERPLIQEAGEDLASEQRFEDSVIMRTVKPHAELEGSRRFLYHHQGESKVFEKVPRGRPRFDWLQDADEAVPLQDAGLDMDLPPQPSPLTSFRTVLMPVDDTMKTLDGPVVGTREHLAGLEGLTQPSEWSLPRSASEVATQTWTVNSEASVERLQPLLSSIRTRPYLCELLEEVAEGADSPDEDEDEEPAVFPCIECSIYFKQKEHLLEHMSQHRRAPGQEPPAELAPLACGECGWAFADPGALERHRQLHQASREKIIEEIQKLKQVPGDAGREARLQCPRCVFGTNSSKAFVQHAKLHAQEPRGPAAQEPFGGSSGAGSPGPDATSLAYQPYEDPSGLSACVFCGFPAPSESLLREHVRLVHAHPHWEEEDGEAFEEEGPASRPGTSQDAYTRFSEAADYFGKAEPLLAPTWQENPAGYDPSLAFGPGCQQLGMRDFPLSKPLPQCSSQRPLGRPAFPSPLASAAYSLQASRSKNVVQPQGLPGHLEDQRHPWSEEEDEEEEEEEELLLASEMEFPPENRVFAPPASPGLIPQSALELKRTFREALQTAVASRAQQQQLCGMVPVVLVAKLGPRVMAAAARAPPRLQPEELGLGGAHPLDFLLLDTPLGGPLGLDPFLDGDPGVTLKPEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTVSPINILQELLATSAAERPPSPLCREAGVPPSGFLTSRRPRLPLTVPFPPTWAEDPGPAYGDGLGSEENAMVAMDLGSPPLPKKSLPVPGPLEQVANRLSSKMAAEVPHGSKQELPDLKAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDTPLGLPPSLTKKSNSPKEIVAGAPRPGLLALAKPLDAPAVNKAIKSPPGFSAKGLAHPPNSPLLKKASLALAGSPTHKNPEDKSPQLSLSPRPASPKAQWPQSEDEGPLNLTSGPEPARDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGPPNPSGPSPKALAKVVSSGGPGSSLEARSPADLHLSPLAKKLPPPPGSPLGHSPTVSPPPTARKMFPGLSSPSLPKKLKPEQMRVEIKREMLPGALHGEPHPSEGPWVAPREDMTPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKPCLIKKEPPAGDLAPALTEDGPPTVAPGPMQAPLPLAPMAGRPGKPGAGPAQIPRELTLAPITGTKHSATGYLGSVAAKRPLQEDRLLPAEVKAKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQSGRPFTKKFRSAGHGRDGDKRPPLGLAPGGLAVVGRGAGGEPGPEAGRAADSGERPLAASPPGTVKAEEHQRQNINKFERRQARPPDASAARGSEEANDLHQKLEEVRQPPPRVRPVPALVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEEWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAAEAP", "length": 1764, "header": "tr|A0ABI0NS70-1|A0ABI0P0I8_BOVIN Computationally mapped isoform of Protein Wiz OS=Bos taurus OX=9913 GN=WIZ PE=3 SV=1 CANONICAL=A0ABI0P0I8-1" }, "locus": { "chromosome": "7", "start_pos": 7730335, "end_pos": 7706828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139661.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139661.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105659.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105659.1" } ] } }, { "isoform_ac": "A0ABI0P0I8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8/entry#A0ABI0P0I8-1", "sequence": { "sequence": "MDGPLAGGLAAPDRPRGPERLPGPAPREDIEGGAEVAEGEGCIFRSTHYLPVTKEGPRDILDGRGGISDGQPHPGLSEALPRATSATHRISSCCWDGGSLDFQPGSPSPHPLGHYPGPLDGRGPWERPLIQEAGEDLASEQRFEDSVIMRTVKPHAELEGSRRFLYHHQGESKVFEKVPRGRPRFDWLQDADEAVPLQDAGLDMDLPPQPSPLTSFRTVLMPVDDTMKTLDGPVVGTREHLAGLEGLTQPSEWSLPRSASEVATQTWTVNSEASVERLQPLLSSIRTRPYLCELLEEVAEGADSPDEDEDEEPAVFPCIECSIYFKQKEHLLEHMSQHRRAPGQEPPAELAPLACGECGWAFADPGALERHRQLHQASREKIIEEIQKLKQVPGDAGREARLQCPRCVFGTNSSKAFVQHAKLHAQEPRGPAAQEPFGGSSGAGSPGPDATSLAYQPYEDPSGLSACVFCGFPAPSESLLREHVRLVHAHPHWEEEDGEAFEEEGPASRPGTSQDAYTRFSEAADYFGKAEPLLAPTWQENPAGYDPSLAFGPGCQQLGMRDFPLSKPLPQCSSQRPLGRPAFPSPLASAAYSLQASRSKNVVQPQGLPGHLEDQRHPWSEEEDEEEEEEEELLLASEMEFPPENRVFAPPASPGLIPQSALELKRTFREALQTAVASRAQQQQLCGMVPVVLVAKLGPRVMAAAARAPPRLQPEELGLGGAHPLDFLLLDTPLGGPLGLDPFLDGDPGVTLKPEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTVSPINILQELLATSAAERPPSPLCREAGVPPSGFLTSRRPRLPLTVPFPPTWAEDPGPAYGDAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDTPLGLPPSLTKKSNSPKEIVAGAPRPGLLALAKPLDAPAVNKAIKSPPGFSAKGLAHPPNSPLLKKASLALAGSPTHKNPEDKSPQLSLSPRPASPKAQWPQSEDEGPLNLTSGPEPARDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGPPNPSGPSPKALAKVVSSGGPGSSLEARSPADLHLSPLAKKLPPPPGSPLGHSPTVSPPPTARKMFPGLSSPSLPKKLKPEQMRVEIKREMLPGALHGEPHPSEGPWVAPREDMTPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKPCLIKKEPPAGDLAPALTEDGPPTVAPGPMQAPLPLAPMAGRPGKPGAGPAQIPRELTLAPITGTKHSATGYLGSVAAKRPLQEDRLLPAEVKAKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQSGRPFTKKFRSAGHGRDGDKRPPLGLAPGGLAVVGRGAGGEPGPEAGRAADSGERPLAASPPGTVKAEEHQRQNINKFERRQARPPDASAARGSEEANDLHQKLEEVRQPPPRVRPVPALVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEEWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAAEAP", "length": 1707, "header": "tr|A0ABI0P0I8-1|A0ABI0P0I8_BOVIN Isoform 1 of Protein Wiz OS=Bos taurus OX=9913 GN=WIZ PE=3 SV=1 CANONICAL=A0ABI0P0I8-1" }, "locus": { "chromosome": "7", "start_pos": 7730335, "end_pos": 7706828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136463.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136463.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106379.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106379.1" } ] } }, { "isoform_ac": "F1MLJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8/entry#F1MLJ0-1", "sequence": { "sequence": 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"length": 1897, "header": "tr|F1MLJ0-1|A0ABI0P0I8_BOVIN Computationally mapped isoform of Protein Wiz OS=Bos taurus OX=9913 GN=WIZ PE=3 SV=5 CANONICAL=A0ABI0P0I8-1" }, "locus": { "chromosome": "7", "start_pos": 7730335, "end_pos": 7706828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013795.8", "url": "https://www.ensembl.org/id/ENSBTAT00000013795.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013795.8", "url": "https://www.ensembl.org/id/ENSBTAP00000013795.8" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0I8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0I8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0I8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0I8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0I8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0I8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1088, "end_pos": 1090, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1133, "end_pos": 1135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1272, "end_pos": 1274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1317, "end_pos": 1319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1487, "end_pos": 1489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1683, "end_pos": 1685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P0I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0I8" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 316, "end_pos": 338, "start_aa": "Phe", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P120-1", "uniprot_ac": "A0ABI0P120", "uniprot_id": "A0ABI0P120_BOVIN", "mass": { "chemical_mass": 21658.0, "monoisotopic_mass": 21658.0 }, "refseq": { "ac": "XP_024832505", "name": "protein LZIC isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832505" }, "gene_names": [ { "name": "LZIC", "type": "recommended", "evidence": [ { "id": "A0ABI0P120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P120" } ] }, { "name": "LZIC", "type": "synonym", "evidence": [ { "id": "XP_024832505", "database": "RefSeq", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR009428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TKMMAGN", "url": "https://omabrowser.org/oma/group/TKMMAGN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR47142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47142:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47142:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06384", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06384", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024832505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832505", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDG9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P120", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P120", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P120-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P120-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDTDEYEETKKETLEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLARDLYTQQKVEILTALRKLGEKLTADDENFLSANAGAILSQFEKVSTDLGLLPSCMNSPLLSLTPHQKY", "length": 191, "header": "tr|A0ABI0P120-1|A0ABI0P120_BOVIN Isoform 1 of Protein LZIC OS=Bos taurus OX=9913 GN=LZIC PE=3 SV=1 CANONICAL=A0ABI0P120-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MDG9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P120/entry#A0A3Q1MDG9-1", "sequence": { "sequence": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDTDEYEETKKETLEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLARDLYTQQKVEILTALRKLGEKLTADDENFLSANAGAILSQFEKVSTDLGSGDKVLALASFEVEKTKK", "length": 190, "header": "tr|A0A3Q1MDG9-1|A0ABI0P120_BOVIN Computationally mapped isoform of Protein LZIC OS=Bos taurus OX=9913 GN=LZIC PE=3 SV=1 CANONICAL=A0ABI0P120-1" }, "locus": { "chromosome": "16", "start_pos": 43609434, "end_pos": 43604217, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084789.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084789.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068972.1", "url": "https://www.ensembl.org/id/ENSBTAP00000068972.1" } ] } }, { "isoform_ac": "A0ABI0P120-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P120/entry#A0ABI0P120-1", "sequence": { "sequence": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDTDEYEETKKETLEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLARDLYTQQKVEILTALRKLGEKLTADDENFLSANAGAILSQFEKVSTDLGLLPSCMNSPLLSLTPHQKY", "length": 191, "header": "tr|A0ABI0P120-1|A0ABI0P120_BOVIN Isoform 1 of Protein LZIC OS=Bos taurus OX=9913 GN=LZIC PE=3 SV=1 CANONICAL=A0ABI0P120-1" }, "locus": { "chromosome": "16", "start_pos": 43617362, "end_pos": 43604217, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148226.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148226.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106354.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106354.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287A837-1", "protein_name": "Protein LZIC", "gene_name": "LZIC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDTDEYEETKKETEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLERDLYTQQKVEILTALRKLGEKLTADDEAFLAANAGAILSQFEKVSTDLGSGDKVLALASFEVEKTKK", "length": 189 }, "evidence": [ { "id": "A0ABI0P120", "url": "https://omabrowser.org/oma/group/A0ABI0P120/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LVC8-1", "protein_name": "Protein LZIC", "gene_name": "Lzic", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDTDEYEETKKETLEQLSEFHDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLERDLYTQQKVEILTALRKLGEKLREDDEAFLLANAGAALSQFEKVSTDLGSGDKVLALAGFEVEKAKK", "length": 190 }, "evidence": [ { "id": "A0ABI0P120", "url": "https://omabrowser.org/oma/group/A0ABI0P120/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q54ID4-1", "protein_name": "Protein LZIC", "gene_name": "lzic", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MASRGKTETNKLKVNIEEQLNRLLAQLQDIEELKEDITQEEYDETKKDTLEQMKEFEQSLKKMMSGDMTLVSELGGVQLAIQAAVSQAFKTPEVIKLFAKKDQNSLRTKLGNIQRDVQLGKISKDAYIDQSVEILAALKKLDFVLSPEEEAFLEKHKSRSMSEFEKVSSNIGQGTKENILSSAASQIKNASK", "length": 192 }, "evidence": [ { "id": "A0ABI0P120", "url": "https://omabrowser.org/oma/group/A0ABI0P120/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5ZKW2-1", "protein_name": "Protein LZIC", "gene_name": "LZIC", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASRGTTETSKLKQNLEEQLDRLMQQLQDLEECREELDADEYEETKKETLEQLSEINDSLKKIMSGDMTLVDELSGMQLAIQAAISQAFKTPEVIRMFAKKQPRQLRTRLAEMDRDLMVGKLGRDLYTQQKVEILTALRKLGEKLTQDDETFLSANAGAALSQFEKVSSDLGSGDKVFALASFEVEKAKQ", "length": 190 }, "evidence": [ { "id": "A0ABI0P120", "url": "https://omabrowser.org/oma/group/A0ABI0P120/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6DHH7-1", "protein_name": "Protein LZIC", "gene_name": "lzic", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASRGKSETSKLRQNMEEQLDRLMQQLQDLEECREDLEEEEYEETKKETLEQLSEFNDSLKKLMSGNMTLVDELGGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDVMVGKLSRDVFTQQKVEILTALRKLGEKLTTEDEAFLAANASATLSHFEKVTASLGSEDKIMALASSGVGKTQT", "length": 190 }, "evidence": [ { "id": "A0ABI0P120", "url": "https://omabrowser.org/oma/group/A0ABI0P120/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K3C3-1", "protein_name": "Protein LZIC", "gene_name": "Lzic", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDADEYEETKKETLEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLERELYTQRKVEILTALRKLGEKLTEDDETFLSANASAVLSQFEKVSTELGSGDKVLALAGFDVEKAKK", "length": 190 }, "evidence": [ { "id": "A0ABI0P120", "url": "https://omabrowser.org/oma/group/A0ABI0P120/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WZA0-1", "protein_name": "Protein LZIC", "gene_name": "LZIC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASRGKTETSKLKQNLEEQLDRLMQQLQDLEECREELDTDEYEETKKETLEQLSEFNDSLKKIMSGNMTLVDELSGMQLAIQAAISQAFKTPEVIRLFAKKQPGQLRTRLAEMDRDLMVGKLERDLYTQQKVEILTALRKLGEKLTADDEAFLSANAGAILSQFEKVSTDLGSGDKILALASFEVEKTKK", "length": 190 }, "evidence": [ { "id": "A0ABI0P120", "url": "https://omabrowser.org/oma/group/A0ABI0P120/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P120", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P120" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P120" }, { "id": "PF06384", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06384" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-catenin-interacting ICAT", "eco_id": "ECO_0000259", "start_pos": 113, "end_pos": 172, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 57, "end_pos": 59 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P4U6-1", "uniprot_ac": "A0ABI0P4U6", "uniprot_id": "A0ABI0P4U6_BOVIN", "mass": { "chemical_mass": 19148.0, "monoisotopic_mass": 19148.0 }, "refseq": {}, "gene_names": [ { "name": "LY6L", "type": "recommended", "evidence": [ { "id": "A0ABI0P4U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4U6" } ] } ], "protein_names": [ { "name": "Lymphocyte antigen 6 family member L", "type": "synonym", "evidence": [ { "id": "A0ABI0P4U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4U6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4U6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4U6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LY6L", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4U6", "locus": { "chromosome": "14", "start_pos": 1391662, "end_pos": 1393575, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000049400", "url": "https://www.ensembl.org/id/ENSBTAG00000049400" } ] } } ], "crossref": [ { "id": "cd23551", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23551", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101904283", "url": "https://www.ncbi.nlm.nih.gov/gene/101904283", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:101904283", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101904283", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR32217", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32217", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32217:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32217:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00021", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00021", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TXJ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4U6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4U6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4U6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4U6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGALVLALWALLVSLDPAGGAREPGEDGPLGCGGSWGRWAHPAATALSWVGAQRTPPRGRCCPTGKNLSCYQCFKVRSPEFCLPAMCSSTDQVCVSHTLIITLRLQVKTLLSKRCAPRCPNTNIEFKWPSNSGVPSKIVRHCCSKSLCNRAPAPQEGPRALSRGLLLRVSLGLLWVLL", "length": 178, "header": "tr|A0ABI0P4U6-1|A0ABI0P4U6_BOVIN Isoform 1 of Lymphocyte antigen 6 family member L OS=Bos taurus OX=9913 GN=LY6L PE=4 SV=1 CANONICAL=A0ABI0P4U6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TXJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4U6/entry#A0AAA9TXJ1-1", "sequence": { "sequence": "MGALVLALWALLVSLDPAGGAREPGKNLSCYQCFKVRSPEFCLPAMCSSTDQVCVSHTLIITLRLQVKTLLSKRCAPRCPNTNIEFKWPSNSGVPSKIVRHCCSKSLCNRAPAPQEGPRALSRGLLLRVSLGLLWVLL", "length": 138, "header": "tr|A0AAA9TXJ1-1|A0ABI0P4U6_BOVIN Computationally mapped isoform of Lymphocyte antigen 6 family member L OS=Bos taurus OX=9913 GN=LY6L PE=4 SV=1 CANONICAL=A0ABI0P4U6-1" }, "locus": { "chromosome": "14", "start_pos": 1393575, "end_pos": 1392005, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069855.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069855.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103052.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103052.1" } ] } }, { "isoform_ac": "A0ABI0P4U6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4U6/entry#A0ABI0P4U6-1", "sequence": { "sequence": "MGALVLALWALLVSLDPAGGAREPGEDGPLGCGGSWGRWAHPAATALSWVGAQRTPPRGRCCPTGKNLSCYQCFKVRSPEFCLPAMCSSTDQVCVSHTLIITLRLQVKTLLSKRCAPRCPNTNIEFKWPSNSGVPSKIVRHCCSKSLCNRAPAPQEGPRALSRGLLLRVSLGLLWVLL", "length": 178, "header": "tr|A0ABI0P4U6-1|A0ABI0P4U6_BOVIN Isoform 1 of Lymphocyte antigen 6 family member L OS=Bos taurus OX=9913 GN=LY6L PE=4 SV=1 CANONICAL=A0ABI0P4U6-1" }, "locus": { "chromosome": "14", "start_pos": 1393575, "end_pos": 1392005, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153377.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153377.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106841.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106841.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:101904283", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101904283", "resource": "KEGG Pathway" } ], "orthologs": 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"XP_024857324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024857324" } ] } ], "protein_names": [ { "name": "RALY RNA binding protein like", "type": "synonym", "evidence": [ { "id": "A0ABI0P1V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V5/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding Raly-like protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024857324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024857324" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RALYL", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V5", 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"https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KQMEDHA", "url": "https://omabrowser.org/oma/group/KQMEDHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MUC2", "url": "https://www.orthodb.org/?gene=A0A3Q1MUC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N0Q3", "url": "https://www.orthodb.org/?gene=F1N0Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13968", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13968", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13968:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13968:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024857324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024857324", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUC2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1V5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1V5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6W0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6W0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6W0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6W0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N0Q3", "url": "https://www.uniprot.org/uniprotkb/F1N0Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N0Q3-1", "url": "https://www.uniprot.org/uniprotkb/F1N0Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGKTQTSNVTNKNDPKSINSRVFIGNLNTAIVKKVDIEAIFSKYGKIVGCSVHKGYAFVQYMSERHARAAVAGENARIIAGQPLDINMAGEPKPYRPKPGNKRPISALYRLESKEPFLSVGGYVFDYDYYRDDFYNRLFDYHGRVPPPPRAVIPLKRPRAAVTTTRRGKGVFSMKGGSRSAVTGSSSSGSKLKSDELQTIKKELTQIKTKIDSLLGRLEKIEKQQKAEAEAQKKQLEASLELIQDECVSENADHSAEEPAEGAPDADGEELTDGVEEDFDEDGAHELFLQIK", "length": 293, "header": "tr|A0ABI0P1V5-1|A0ABI0P1V5_BOVIN Isoform 1 of RALY RNA binding protein like OS=Bos taurus OX=9913 GN=RALYL PE=3 SV=1 CANONICAL=A0ABI0P1V5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MUC2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V5/entry#A0A3Q1MUC2-1", "sequence": { "sequence": "MTMYRSKRRHQRYINMAGEPKPYRPKPGNKRPISALYRLESKEPFLSVGLFDYHGRVPPPPRAVIPLKRPRAAVTTTRRGKGVFSMKGGSRSAVTGSSSSGSKLKSDELQTIKKELTQIKTKIDSLLGRLEKIEKQQKAEAVSTDKVISSNE", "length": 152, "header": "tr|A0A3Q1MUC2-1|A0ABI0P1V5_BOVIN Computationally mapped isoform of RALY RNA binding protein like OS=Bos taurus OX=9913 GN=RALYL PE=3 SV=2 CANONICAL=A0ABI0P1V5-1" }, "locus": { "chromosome": "14", "start_pos": 77921301, "end_pos": 77668442, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071675.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071675.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058432.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058432.2" } ] } }, { "isoform_ac": "A0ABI0P1V5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V5/entry#A0ABI0P1V5-1", "sequence": { "sequence": "MTGKTQTSNVTNKNDPKSINSRVFIGNLNTAIVKKVDIEAIFSKYGKIVGCSVHKGYAFVQYMSERHARAAVAGENARIIAGQPLDINMAGEPKPYRPKPGNKRPISALYRLESKEPFLSVGGYVFDYDYYRDDFYNRLFDYHGRVPPPPRAVIPLKRPRAAVTTTRRGKGVFSMKGGSRSAVTGSSSSGSKLKSDELQTIKKELTQIKTKIDSLLGRLEKIEKQQKAEAEAQKKQLEASLELIQDECVSENADHSAEEPAEGAPDADGEELTDGVEEDFDEDGAHELFLQIK", "length": 293, "header": "tr|A0ABI0P1V5-1|A0ABI0P1V5_BOVIN Isoform 1 of RALY RNA binding protein like OS=Bos taurus OX=9913 GN=RALYL PE=3 SV=1 CANONICAL=A0ABI0P1V5-1" }, "locus": { "chromosome": "14", "start_pos": 78133281, "end_pos": 77668459, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144161.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144161.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105432.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105432.1" } ] } }, { "isoform_ac": "A0ABI0P6W0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V5/entry#A0ABI0P6W0-1", "sequence": { "sequence": "MTGKTQTSNVTNKNDPKSINSRVFIGNLNTAIVKKVDIEAIFSKYGKIVGCSVHKGYAFVQYMSERHARAAVAGENARIIAGQPLDINMAGEPKPYRPKPGNKRPISALYSGYVFDYDYYRDDFYNRLFDYHGRVPPPPRAVIPLKRPRAAVTTTRRGKGVFSMKGGSRSAVTGSSSSGSKLKSDELQTIKKELTQIKTKIDSLLGRLEKIEKQQKAEAEAQKKQLEASLELIQDECVSENADHSAEEPAEGAPDADGEELTDGVEEDFDEDGAHELFLQIK", "length": 282, "header": "tr|A0ABI0P6W0-1|A0ABI0P6W0_BOVIN Computationally mapped isoform of RALY RNA binding protein like OS=Bos taurus OX=9913 GN=RALYL PE=3 SV=1 CANONICAL=A0ABI0P1V5-1" }, "locus": { "chromosome": "14", "start_pos": 78133281, "end_pos": 77668459, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141063.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141063.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107605.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107605.1" } ] } }, { "isoform_ac": "F1N0Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V5/entry#F1N0Q3-1", "sequence": { "sequence": "MRMVLPWLSLCDCWLPSVSEQQSYCKAGAQPVSLSPWSKQLLLRKSDFFFRMTMYRSKRRHQRYINMAGEPKPYRPKPGNKRPISALYRLESKEPFLSVGGYVFDYDYYRDDFYNRLFDYHGRVPPPPRAVIPLKRPRAAVTTTRRGKGVFSMKGGSRSAVTGSSSSGSKLKSDELQTIKKELTQIKTKIDSLLGRLEKIEKQQKAEAEAQKKQLEASLELIQDECVSENADHSAEEPAEGAPDADGEELTDGVEEDFDEDGAHELFLQIK", "length": 271, "header": "tr|F1N0Q3-1|A0ABI0P1V5_BOVIN Computationally mapped isoform of RALY RNA binding protein like OS=Bos taurus OX=9913 GN=RALYL PE=3 SV=3 CANONICAL=A0ABI0P1V5-1" }, "locus": { "chromosome": "14", "start_pos": 77921454, "end_pos": 77668459, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023563.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023563.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023563.6", "url": "https://www.ensembl.org/id/ENSBTAP00000023563.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AIC1-1", "protein_name": "RALY RNA binding protein-like", "gene_name": "Ralyl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGKTQTSNVTNKNDPKSINSRVFIGNLNTAIVKKVDIEAIFSKYGKIVGCSVHKGYAFVQYMSERHARAAVAGENARVIAGQPLDINMAGEPKPYRPKPGSKRPLSALYRLESKEPFLSVGGYVFDYDYYRDDFYNRLFDYHGRVPPPPRAVIPLKRPRVAVTTTRRGKGVFSMKGGSRSSVGGSSSSGSKLKSDELQTIKKELTQIKTKIDSLLGRLEKIEKQQKAEAEAQKKQLEESIELIQDECVSENADHSTEEPAEGGQEADGGEMTDGVEEDFDEDGGHELFLQIK", "length": 293 }, "evidence": [ { "id": "A0ABI0P1V5", "url": "https://omabrowser.org/oma/group/A0ABI0P1V5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86SE5-1", "protein_name": "RNA-binding Raly-like protein", "gene_name": "RALYL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGKTQTSNVTNKNDPKSINSRVFIGNLNTAIVKKVDIEAIFSKYGKIVGCSVHKGYAFVQYMSERHARAAVAGENARVIAGQPLDINMAGEPKPYRPKPGNKRPLSALYRLESKEPFLSVGGYVFDYDYYRDDFYNRLFDYHGRVPPPPRAVIPLKRPRVAVTTTRRGKGVFSMKGGSRSTASGSTGSKLKSDELQTIKKELTQIKTKIDSLLGRLEKIEKQQKAEAEAQKKQLEESLVLIQEECVSEIADHSTEEPAEGGPDADGEEMTDGIEEDFDEDGGHELFLQIK", "length": 291 }, "evidence": [ { "id": "A0ABI0P1V5", "url": "https://omabrowser.org/oma/group/A0ABI0P1V5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BTF8-1", "protein_name": "RNA-binding Raly-like protein", "gene_name": "Ralyl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGKTQTSNITNKNDPKSINSRVFIGNLNTAIVKKVDIEAIFSKYGKIVGCSVHKGYAFVQYMSERHARAAVAGENARVIAGQPLDINMAGEPKPYRPKPGSKRPLSALYRLESKEPFLSVGGYVFDYDYYRDDFYNRLFDYHGRVPPPPRAVIPLKRPRVAVTTTRRGKGVFSMKGGSRSTVGGSSSSGSKLKSDELQTIKKELTQIKTKIDSLLGRLEKIEKQQKAEAEAQKKQLEESIELIQDECVSENADHSTEEPAEGGQEADGGEMTDGVEEDFDEDGGHELFLQIK", "length": 293 }, "evidence": [ { "id": "A0ABI0P1V5", "url": "https://omabrowser.org/oma/group/A0ABI0P1V5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P1V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V5" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 92, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P1E3-1", "uniprot_ac": "A0ABI0P1E3", "uniprot_id": "A0ABI0P1E3_BOVIN", "mass": { "chemical_mass": 80713.0, "monoisotopic_mass": 80713.0 }, "refseq": { "ac": "NP_001179414", "name": "RNA polymerase-associated protein RTF1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179414" }, "gene_names": [ { "name": "RTF1", "type": "recommended", "evidence": [ { "id": "A0ABI0P1E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1E3" } ] }, { "name": "RTF1", "type": "synonym", "evidence": [ { "id": "NP_001179414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179414" } ] } ], "protein_names": [ { "name": "RNA polymerase-associated protein RTF1 homolog", "type": "recommended", "evidence": [ { "id": "A0ABI0P1E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1E3/entry#names_and_taxonomy" } ] }, { "name": "RNA polymerase-associated protein RTF1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001179414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179414" } ] }, { "name": "Rtf1, Paf1/RNA polymerase II complex component, homolog", "type": "synonym", "evidence": [ { "id": "NP_001179414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179414" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1E3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1E3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RTF1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1E3", "locus": { "chromosome": "10", "start_pos": 36909093, "end_pos": 36864027, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001671", "url": "https://www.ensembl.org/id/ENSBTAG00000001671" } ] } } ], "crossref": [ { "id": "ENSBTAG00000001671", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001671", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "518260", "url": "https://www.ncbi.nlm.nih.gov/gene/518260", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:518260", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518260", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISGCYAR", "url": "https://omabrowser.org/oma/group/ISGCYAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N6E9", "url": "https://www.orthodb.org/?gene=F1N6E9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13115", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13115", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13115:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13115:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03126", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03126", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179414", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179414", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SAN2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAN2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1E3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1E3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1E3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6E9", "url": "https://www.uniprot.org/uniprotkb/F1N6E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6E9-1", "url": "https://www.uniprot.org/uniprotkb/F1N6E9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGRLCVGRTAAAAAAATAAVAVPLAGGQEGSPGGVRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSNSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKKRFEIRKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTTSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGSDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMKNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMNKGQGKDKDLNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "length": 714, "header": "tr|A0ABI0P1E3-1|A0ABI0P1E3_BOVIN Isoform 1 of RNA polymerase-associated protein RTF1 homolog OS=Bos taurus OX=9913 GN=RTF1 PE=4 SV=1 CANONICAL=A0ABI0P1E3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SAN2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1E3/entry#A0AAA9SAN2-1", "sequence": { "sequence": "MRGRLCVGRTAAAAAAATAAVAVPLAGGQEGSPGGVRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSNSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKKRFEIRKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVSLISGHIISPLAVLFNSLGILLKSACKKAAHLVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTTSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGSDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMKNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMNKGQGKDKDLNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "length": 747, "header": "tr|A0AAA9SAN2-1|A0ABI0P1E3_BOVIN Computationally mapped isoform of RNA polymerase-associated protein RTF1 homolog OS=Bos taurus OX=9913 GN=RTF1 PE=4 SV=1 CANONICAL=A0ABI0P1E3-1" }, "locus": { "chromosome": "10", "start_pos": 36908457, "end_pos": 36864202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113095.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113095.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079229.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079229.1" } ] } }, { "isoform_ac": "A0ABI0P1E3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1E3/entry#A0ABI0P1E3-1", "sequence": { "sequence": "MRGRLCVGRTAAAAAAATAAVAVPLAGGQEGSPGGVRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSNSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKKRFEIRKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTTSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGSDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMKNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMNKGQGKDKDLNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "length": 714, "header": "tr|A0ABI0P1E3-1|A0ABI0P1E3_BOVIN Isoform 1 of RNA polymerase-associated protein RTF1 homolog OS=Bos taurus OX=9913 GN=RTF1 PE=4 SV=1 CANONICAL=A0ABI0P1E3-1" }, "locus": { "chromosome": "10", "start_pos": 36908457, "end_pos": 36864202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148651.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148651.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104456.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104456.1" } ] } }, { "isoform_ac": "F1N6E9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1E3/entry#F1N6E9-1", "sequence": { "sequence": "MRGRLCVGRTAAAAAAATAAVAVPLAGGQEGSPGGVRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSNSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKKRFEIRKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTTSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGSDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMKNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMNKAQK", "length": 645, "header": "tr|F1N6E9-1|A0ABI0P1E3_BOVIN Computationally mapped isoform of RNA polymerase-associated protein RTF1 homolog OS=Bos taurus OX=9913 GN=RTF1 PE=4 SV=3 CANONICAL=A0ABI0P1E3-1" }, "locus": { "chromosome": "10", "start_pos": 36907837, "end_pos": 36864202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002191.8", "url": "https://www.ensembl.org/id/ENSBTAT00000002191.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002191.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002191.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:518260", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518260", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AGX2-1", "protein_name": "RNA polymerase-associated protein RTF1 homolog", "gene_name": "Rtf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRGRLCVGRAAAVAAAVVAAVAVPLAGGQEGSPDGVRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKVEKKGAMKKQANKAASSGSSDRDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEDDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKEFSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMRNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGALPDAPKEVSKGQGKDKDLNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "length": 715 }, "evidence": [ { "id": "A0ABI0P1E3", "url": "https://omabrowser.org/oma/group/A0ABI0P1E3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZQL8-1", "protein_name": "RNA polymerase-associated protein RTF1 homolog", "gene_name": "RTF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRGALCVPVGRAARGRPGRSERRAAAGGEGRGEAASAMVKKRKGRVLIDSDTEDSGSEENLDQELLSLAKRKRSDSEEKEPPASKPTASSDSETSDSDDEWTVGGSKNKKKGKAGKAEKKGAMKKQMNKAASSGSSDKDSSAESSAPEEGEVSDSESNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRSSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGSDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKEVSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHSMKNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKDMSKGQGKDKDVNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "length": 707 }, "evidence": [ { "id": "A0ABI0P1E3", "url": "https://omabrowser.org/oma/group/A0ABI0P1E3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2AQ19-1", "protein_name": "RNA polymerase-associated protein RTF1 homolog", "gene_name": "Rtf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGRLCVGRAAAVAAAVAAAAVAVPLAGGQEGSQGGVRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKTRKVEKKGAMKKQANKAASSGSSDRDSSAESSAPEEGEVSDSESSSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEDDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMRNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMSKGQGKDKDLNSKTASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "length": 715 }, "evidence": [ { "id": "A0ABI0P1E3", "url": "https://omabrowser.org/oma/group/A0ABI0P1E3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P53064-1", "protein_name": "RNA polymerase-associated protein RTF1", "gene_name": "RTF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSDLDEDLLALAGADESEEEDQVLTTTSAKRAKNNDQSLSKKRRIEVGSVEDDDEEDDYNPYSVGNADYGSEEEEEANPFPLEGKYKDESDREHLESLPEMERETLLFERSQIMQKYQERKLFRARGRDMKEQQQRAKNDEDSRKTRASTRSTHATGHSDIKASKLSQLKKQRARKNRHYSDNEDEDDEEDYREEDYKDDEGSEYGDDEEYNPFDRRDTYDKREEVEWAEEEDEQDREPEISDFNKLRIGRSFVAKFCFYPGFEDAVKGCYGRVNVGTDKRTGKTSYRMVRIERVFLQKPYNMGKFYTNQYFGVTQGKDRKVFQMNYFSDGLFAEDEYQRYLRALDNSQMIKPSLHSLSNKTKEVMDFVNTPLTDKTTDEVVRHRMQFNKKLSGTNAVLEKTVLREKLQYAKETNNEKDIAKYSAQLRNFEKRMSVYEKHHENDQSDIKKLGELTSKNRKLNMSNIRNAEHVKKEDSNNFDSKSDPFSRLKTRTKVYYQEIQKEENAKAKEIAQQEKLQEDKDAKDKREKELLVAQFRRLGGLERMVGELDIKFDLKF", "length": 558 }, "evidence": [ { "id": "A0ABI0P1E3", "url": "https://omabrowser.org/oma/group/A0ABI0P1E3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q92541-1", "protein_name": "RNA polymerase-associated protein RTF1 homolog", "gene_name": "RTF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGRLCVGRAAAAAAAVAVPLAGGQEGSPGGGRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMKNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMSKGQGKDKDLNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "length": 710 }, "evidence": [ { "id": "A0ABI0P1E3", "url": "https://omabrowser.org/oma/group/A0ABI0P1E3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9C950-1", "protein_name": "Protein RTF1 homolog", "gene_name": "VIP5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGDLENLLLEAAGRTNSAGRSRHPPSSRRREGSYSDGSSDSRDDSDEDRGYASRKPSGSQVPLKKRLEAEREDRAARVEGGYGDGPSDREGDSSEESDFGDDLYKNEEDRQKLAGMTEFQREMILSERADKKGDKNFTEKLRSKRESEKTPVSKKETQPLPASRGVRSSARSADRAAAKDDALNELRAKRMKQQDPAALRKLRDASKGGSGSRDFSSTKRKPLASSNLSSSSQSDSDSRSQSDDEGSNGGMLDSDDDRSDVPTFEDVKEVTIRRSKLAKWLMEPFFEELIVGCFVRVGIGRSKSGPIYRLCWVKNVDATDPDKTYKLENKTTHKYLNVVWGNETSAARWQMAMISDGHPLEEEYRQWIREVERTNGRMPTKQDISEKKEAIQRTNSFVYSAETVKQMLQEKKSASVRPMNVAAEKDRLRKELEIAQSKNDEAGVERIKSKIKQLDASRNKKGVDKKALKLAEMNKKNRAENFKNASEVKSITASLKAGEAGYDPFSRRWTRSSNYYNGKNKGKDGEENEAAVAAAVETNGADAGAGVEATEAALEAAAEAGKLIDTRAPIGQGAEHNQLHNFELSLSLTALQKYGGPQGVQKAFMARKQLTEATVGCRVAENDGKRHGLTLTVSDYKRRRGLL", "length": 643 }, "evidence": [ { "id": "A0ABI0P1E3", "url": "https://omabrowser.org/oma/group/A0ABI0P1E3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W261-1", "protein_name": "RNA polymerase-associated protein Rtf1", "gene_name": "Rtf1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P0U3-1", "uniprot_ac": "A0ABI0P0U3", "uniprot_id": "A0ABI0P0U3_BOVIN", "mass": { "chemical_mass": 36126.0, "monoisotopic_mass": 36126.0 }, "refseq": { "ac": "XP_003587594", "name": "apoptosis-enhancing nuclease isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587594" }, "gene_names": [ { "name": "AEN", "type": "recommended", "evidence": [ { "id": "A0ABI0P0U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0U3" } ] }, { "name": "AEN", "type": "synonym", "evidence": [ { "id": "XP_003587594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587594" } ] } ], "protein_names": [ 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Gene", "id": "ENSBTAG00000017632", "url": "https://www.ensembl.org/id/ENSBTAG00000017632" } ] } } ], "crossref": [ { "id": "ENSBTAG00000017632", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017632", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "614749", "url": "https://www.ncbi.nlm.nih.gov/gene/614749", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"categories": [ "Protein" ] }, { "id": "F1MZX4", "url": "https://www.uniprot.org/uniprotkb/F1MZX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZX4-1", "url": "https://www.uniprot.org/uniprotkb/F1MZX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGMVPQEASESVQCPSPSLASPNAKDVLRRKHKRKSRQHQRFMARKALLQEQGLLSPLWEPGPSPLPTLPGAPPGTEATSSARQRPRAEPGGAGCSRKPAPRDSAGPLPSKCVAIDCEMVGTGPRGRVSELARCSVVSYHGEVLYDKYIRPEMPIVDYRTRWSGITRQHMRKATPFQVAQKEILKLLKGKVVVGHALHNDFQALKYIHPRGQTRDTTSVPSLLSQPGLHVRNRVSLKDLALQLLHKKIQVGQHGHSSVEDAVTAMELYRLVEVQWEQQVASSLRAPPEDREPDSSTDMEQYMEDQYWPADPAQGTSGDPGAAPGRRE", "length": 327, "header": "tr|A0ABI0P0U3-1|A0ABI0P0U3_BOVIN Isoform 1 of Apoptosis enhancing nuclease OS=Bos taurus OX=9913 GN=AEN PE=4 SV=1 CANONICAL=A0ABI0P0U3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P0U3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0U3/entry#A0ABI0P0U3-1", "sequence": { "sequence": 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"MGFPRQEYGVGCRFLLQEIFPTQGSCVSCIGRLLPCWQITSQVSLALSGAQMGMVPQEASESVQCPSPSLASPNAKDVLRRKHKRKSRQHQRFMARKALLQEQGLLSPLWEPGPSPLPTLPGAPPGTEATSSARQRPRAEPGGAGCSRKPAPRDSAGPLPSKCVAIDCEMVGTGPRGRVSELARCSVVSYHGEVLYDKYIRPEMPIVDYRTRWSGITRQHMRKATPFQVAQKEILKLLKGKVVVGHALHNDFQALKYIHPRGQTRDTTSVPSLLSQPGLHVRNRVSLKDLALQLLHKKIQVGQHGHSSVEDAVTAMELYRLVEVQWEQQVASSLRAPPEDREPDSSTDMEQYMEDQYWPADPAQGTSGDPGAAPGRRE", "length": 378, "header": "tr|F1MZX4-1|A0ABI0P0U3_BOVIN Computationally mapped isoform of Apoptosis enhancing nuclease OS=Bos taurus OX=9913 GN=AEN PE=4 SV=4 CANONICAL=A0ABI0P0U3-1" }, "locus": { "chromosome": "21", "start_pos": 19601249, "end_pos": 19593670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023454.8", "url": "https://www.ensembl.org/id/ENSBTAT00000023454.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023454.7", "url": "https://www.ensembl.org/id/ENSBTAP00000023454.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": 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exchanger OS=Bos taurus OX=9913 GN=LOC518911 PE=3 SV=1 CANONICAL=A0ABI0P4H4-1" }, "locus": { "chromosome": "X", "start_pos": 71011958, "end_pos": 70957456, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143206.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143206.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106047.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106047.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4H4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4H4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of pH", "id": "GO:0006885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006885", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4H4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4H4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12125", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12125", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005221479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221479", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVJ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M118", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M118", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M118-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M118-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9I3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9I3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCG1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTL5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NTL5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NTL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3D5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3D5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3D5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3D5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MLG0", "url": "https://www.uniprot.org/uniprotkb/F1MLG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MLG0-1", "url": "https://www.uniprot.org/uniprotkb/F1MLG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQNTSVMEDQNEDESPKKSTLWQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR", "length": 563, "header": "tr|A0ABI0P3D5-1|A0ABI0P3D5_BOVIN Isoform 1 of F-box and WD repeat domain containing 11 OS=Bos taurus OX=9913 GN=FBXW11 PE=4 SV=1 CANONICAL=A0ABI0P3D5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3D5/entry#A0A3Q1LVJ4-1", "sequence": { "sequence": "MEPDSVIEDKTIELMNTSVMEDQNEDESPKKSTLWQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR", "length": 529, "header": "tr|A0A3Q1LVJ4-1|A0ABI0P3D5_BOVIN Computationally mapped isoform of F-box and WD repeat domain containing 11 OS=Bos taurus OX=9913 GN=FBXW11 PE=4 SV=3 CANONICAL=A0ABI0P3D5-1" }, "locus": { "chromosome": "20", "start_pos": 3809417, "end_pos": 3687343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081345.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081345.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061427.3", "url": "https://www.ensembl.org/id/ENSBTAP00000061427.3" } ] } }, { "isoform_ac": "A0A3Q1M118-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3D5/entry#A0A3Q1M118-1", "sequence": { "sequence": "MQRPDSLEKTLMLEMIEGGRRGWHRMRWLDHITDSVDNTSVMEDQNEDESPKKSTLWQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR", "length": 551, "header": "tr|A0A3Q1M118-1|A0ABI0P3D5_BOVIN Computationally mapped isoform of F-box and WD repeat domain containing 11 OS=Bos taurus OX=9913 GN=FBXW11 PE=4 SV=2 CANONICAL=A0ABI0P3D5-1" }, "locus": { "chromosome": "20", "start_pos": 3797018, "end_pos": 3687343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075176.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075176.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066952.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066952.2" } ] } }, { "isoform_ac": "A0A3Q1M9I3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3D5/entry#A0A3Q1M9I3-1", "sequence": { "sequence": "MIKFQCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR", "length": 532, "header": "tr|A0A3Q1M9I3-1|A0ABI0P3D5_BOVIN Computationally mapped isoform of F-box and WD repeat domain containing 11 OS=Bos taurus OX=9913 GN=FBXW11 PE=4 SV=2 CANONICAL=A0ABI0P3D5-1" }, "locus": { "chromosome": "20", "start_pos": 3768555, "end_pos": 3687343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071665.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071665.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065106.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065106.2" } ] } }, { "isoform_ac": "A0A3Q1MCG1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3D5/entry#A0A3Q1MCG1-1", "sequence": { "sequence": "MQRPDSLEKTLMLEMIEGGRRGWHRMRWLDHITDSVDISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR", "length": 530, "header": "tr|A0A3Q1MCG1-1|A0ABI0P3D5_BOVIN Computationally mapped isoform of F-box and WD repeat domain containing 11 OS=Bos taurus OX=9913 GN=FBXW11 PE=4 SV=2 CANONICAL=A0ABI0P3D5-1" }, "locus": { "chromosome": "20", "start_pos": 3797018, "end_pos": 3687343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079706.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079706.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068034.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068034.2" } ] } }, { "isoform_ac": "A0ABI0NTL5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3D5/entry#A0ABI0NTL5-1", "sequence": { "sequence": "MEPDSVIEDKTIELMISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR", "length": 508, "header": "tr|A0ABI0NTL5-1|A0ABI0P3D5_BOVIN Computationally mapped isoform of F-box and WD repeat domain containing 11 OS=Bos taurus OX=9913 GN=FBXW11 PE=4 SV=1 CANONICAL=A0ABI0P3D5-1" }, "locus": { "chromosome": "20", "start_pos": 3809417, "end_pos": 3687343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149507.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149507.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106720.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106720.1" } ] } }, { "isoform_ac": "A0ABI0P3D5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3D5/entry#A0ABI0P3D5-1", "sequence": { "sequence": "MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQNTSVMEDQNEDESPKKSTLWQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR", "length": 563, "header": "tr|A0ABI0P3D5-1|A0ABI0P3D5_BOVIN Isoform 1 of F-box and WD repeat domain containing 11 OS=Bos taurus OX=9913 GN=FBXW11 PE=4 SV=1 CANONICAL=A0ABI0P3D5-1" }, "locus": { "chromosome": "20", "start_pos": 3809417, "end_pos": 3687343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136293.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136293.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105086.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105086.1" } ] } }, { "isoform_ac": "F1MLG0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3D5/entry#F1MLG0-1", "sequence": { "sequence": "MIKFQCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQNTSVMEDQNEDESPKKSTLWQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR", "length": 553, "header": "tr|F1MLG0-1|A0ABI0P3D5_BOVIN Computationally mapped isoform of F-box and WD repeat domain containing 11 OS=Bos taurus OX=9913 GN=FBXW11 PE=4 SV=3 CANONICAL=A0ABI0P3D5-1" }, "locus": { "chromosome": "20", "start_pos": 3768555, "end_pos": 3687343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061118.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061118.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053291.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053291.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3D5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3D5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3D5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3D5" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3D5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3D5" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3D5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3D5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" }, { "start_pos": 549, "end_pos": 551, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P3D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3D5" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 150, "end_pos": 188, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 50, "end_pos": 52 }, { "start_pos": 549, "end_pos": 551 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", 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"url": "https://www.ebi.ac.uk/interpro/entry/IPR013154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M0E0", "url": "https://www.orthodb.org/?gene=A0A3Q1M0E0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MZN9", "url": "https://www.orthodb.org/?gene=F1MZN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43880", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43880", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43880:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43880:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00107", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00107", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-71384", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-71384", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M0E0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0E0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0E0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZD4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZD4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S8R0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S8R0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P400", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P400-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZN9", "url": "https://www.uniprot.org/uniprotkb/F1MZN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZN9-1", "url": "https://www.uniprot.org/uniprotkb/F1MZN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTTGKVIRCKAAIVWKPGGSFSIEEVEVAPPKAKEVRIKMVATALCGTEMKMLKDKNLQHQHYPIIMGHEGAGIVESVGEGVSTVKAGDKVIALFLPQCGECTSCLNSADNFCIKLKQAETHLMSDGTSRFTCKGKPVYHFGNTSTFSEYTVMDEISVAKIDAAAPLEKVFLVSCGFSTGYGGAINTAKVTPGSTCAVFGLGGVGLSVIMGCKAAGATRIIAVDINKDKFEKAKEVGATECINPQDYEKPIQEVLFDLTGDGVDFSFEVIGNPETVAAALASCRESHGVCVIIGLIIGVQLNISGHLFFSGRSLKGSVYGGWKGRDGASKLVSDYMAKKINLDALITHSLNLDKINEAVELMKTGKWQVTHTIFMSEYLGPREMVCGGGGGQGSHGWRSHIQAAEGSFRNLQKISFPYAFCFITTL", "length": 427, "header": "tr|A0ABI0P400-1|A0ABI0P400_BOVIN Isoform 1 of Alcohol dehydrogenase 6 OS=Bos taurus OX=9913 GN=ADH6 PE=1 SV=1 CANONICAL=A0ABI0P400-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M0E0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400/entry#A0A3Q1M0E0-1", "sequence": { "sequence": "MSTTGKMVATALCGTEMKMLKDKNLQHQHYPIIMGHEGAGIVESVGEGVSTVKAGDKVIALFLPQCGECTSCLNSADNFCIKLKQAETHLMSDGTSRFTCKGKPVYHFGNTSTFSEYTVMDEISVAKIDAAAPLEKVFLVSCGFSTGYGGAINTAKVTPGSTCAVFGLGGVGLSVIMGCKAAGATRIIAVDINKDKFEKAKEVGATECINPQDYEKPIQEVLFDLTGDGVDFSFEVIGNPETVAAALASCRESHGVCVIIGLIIGVQLNISGHLFFSGRSLKGSVYGGWKGRDGASKLVSDYMAKKINLDALITHSLNLDKINEAVELMKTGKCVRCVLLL", "length": 341, "header": "tr|A0A3Q1M0E0-1|A0ABI0P400_BOVIN Computationally mapped isoform of Alcohol dehydrogenase 6 OS=Bos taurus OX=9913 GN=ADH6 PE=1 SV=1 CANONICAL=A0ABI0P400-1" }, "locus": { "chromosome": "6", "start_pos": 25429575, "end_pos": 25414300, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080455.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080455.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063106.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063106.1" } ] } }, { "isoform_ac": "A0AAA9RZD4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400/entry#A0AAA9RZD4-1", "sequence": { "sequence": "MSTTGKVIRCKAAIVWKPGGSFSIEEVEVAPPKAKEVRIKMVATALCGTEMKMLKDKNLQHQHYPIIMGHEGAGIVESVGEGVSTVKAGDKVIALFLPQCGECTSCLNSADNFCIKLKQAETHLMSDGTSRFTCKGKPVYHFGNTSTFSEYTVMDEISVAKIDAAAPLEKVFLVSCGFSTGYGGAINTAKVTPGSTCAVFGLGGVGLSVIMGCKAAGATRIIAVDINKDKFEKAKEVGATECINPQDYEKPIQEVLFDLTGDGVDFSFEVIGNPETVAGKAEMVPLNWFLIIWQRRL", "length": 297, "header": "tr|A0AAA9RZD4-1|A0ABI0P400_BOVIN Computationally mapped isoform of Alcohol dehydrogenase 6 OS=Bos taurus OX=9913 GN=ADH6 PE=1 SV=1 CANONICAL=A0ABI0P400-1" }, "locus": { "chromosome": "6", "start_pos": 25428810, "end_pos": 25414300, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108260.2", "url": "https://www.ensembl.org/id/ENSBTAT00000108260.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075151.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075151.1" } ] } }, { "isoform_ac": "A0AAA9S8R0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400/entry#A0AAA9S8R0-1", "sequence": { "sequence": "MLSKAHLTSHSRMSGSSIFICGQKNTEKISMSTTGKVIRCKAAIVWKPGGSFSIEEVEVAPPKAKEVRIKMVATALCGTEMKMLKDKNLQHQHYPIIMGHEGAGIVESVGEGVSTVKAGDKVIALFLPQCGECTSCLNSADNFCIKLKQAETHLMSDGTSRFTCKGKPVYHFGNTSTFSEYTVMDEISVAKIDAAAPLEKVFLVSCGFSTGYGGAINTAKVTPGSTCAVFGLGGVGLSVIMGCKAAGATRIIAVDINKDKFEKAKEVGATECINPQDYEKPIQEVLFDLTGDGVDFSFEVIGNPETVAAALASCRESHGVCVIIGLIIGVQLNISGHLFFSGRSLKGSVYGGWKGRDGASKLVSDYMAKKINLDALITHSLNLDKINEAVELMKTGKCVRCVLLL", "length": 405, "header": "tr|A0AAA9S8R0-1|A0ABI0P400_BOVIN Computationally mapped isoform of Alcohol dehydrogenase 6 OS=Bos taurus OX=9913 GN=ADH6 PE=1 SV=1 CANONICAL=A0ABI0P400-1" }, "locus": { "chromosome": "6", "start_pos": 25429575, "end_pos": 25411653, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123501.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123501.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081660.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081660.1" } ] } }, { "isoform_ac": "A0ABI0P400-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400/entry#A0ABI0P400-1", "sequence": { "sequence": "MSTTGKVIRCKAAIVWKPGGSFSIEEVEVAPPKAKEVRIKMVATALCGTEMKMLKDKNLQHQHYPIIMGHEGAGIVESVGEGVSTVKAGDKVIALFLPQCGECTSCLNSADNFCIKLKQAETHLMSDGTSRFTCKGKPVYHFGNTSTFSEYTVMDEISVAKIDAAAPLEKVFLVSCGFSTGYGGAINTAKVTPGSTCAVFGLGGVGLSVIMGCKAAGATRIIAVDINKDKFEKAKEVGATECINPQDYEKPIQEVLFDLTGDGVDFSFEVIGNPETVAAALASCRESHGVCVIIGLIIGVQLNISGHLFFSGRSLKGSVYGGWKGRDGASKLVSDYMAKKINLDALITHSLNLDKINEAVELMKTGKWQVTHTIFMSEYLGPREMVCGGGGGQGSHGWRSHIQAAEGSFRNLQKISFPYAFCFITTL", "length": 427, "header": "tr|A0ABI0P400-1|A0ABI0P400_BOVIN Isoform 1 of Alcohol dehydrogenase 6 OS=Bos taurus OX=9913 GN=ADH6 PE=1 SV=1 CANONICAL=A0ABI0P400-1" }, "locus": { "chromosome": "6", "start_pos": 25429067, "end_pos": 25414300, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142694.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142694.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105805.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105805.1" } ] } }, { "isoform_ac": "F1MZN9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400/entry#F1MZN9-1", "sequence": { "sequence": "MSTTGKVIRCKAAIVWKPGGSFSIEEVEVAPPKAKEVRIKMVATALCGTEMKMLKDKNLQHQHYPIIMGHEGAGIVESVGEGVSTVKAGDKVIALFLPQCGECTSCLNSADNFCIKLKQAETHLMSDGTSRFTCKGKPVYHFGNTSTFSEYTVMDEISVAKIDAAAPLEKVFLVSCGFSTGYGGAINTAKVTPGSTCAVFGLGGVGLSVIMGCKAAGATRIIAVDINKDKFEKAKEVGATECINPQDYEKPIQEVLFDLTGDGVDFSFEVIGNPETVAAALASCRESHGVCVIIGLIIGVQLNISGHLFFSGRSLKGSVYGGWKGRDGASKLVSDYMAKKINLDALITHSLNLDKINEAVELMKTGKCVRCVLLL", "length": 375, "header": "tr|F1MZN9-1|A0ABI0P400_BOVIN Computationally mapped isoform of Alcohol dehydrogenase 6 OS=Bos taurus OX=9913 GN=ADH6 PE=1 SV=3 CANONICAL=A0ABI0P400-1" }, "locus": { "chromosome": "6", "start_pos": 25429575, "end_pos": 25414300, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009191.7", "url": "https://www.ensembl.org/id/ENSBTAT00000009191.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009191.6", "url": "https://www.ensembl.org/id/ENSBTAP00000009191.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 192, "start_aa": "Thr", "end_pos": 192, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr192", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-71384", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-71384", "resource": "Reactome", "description": "Ethanol oxidation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P400", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P400", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400" } ], "pmid": "" }, { "name": "alcohol dehydrogenase (NAD+) activity", "id": "GO:0004022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004022", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P400", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400" } ], "pmid": "" }, { "name": "all-trans-retinol dehydrogenase (NAD+) activity", "id": "GO:0004745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004745", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P400", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P400", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "retinol metabolic process", "id": "GO:0042572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042572", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P400", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400" } ], "pmid": "" }, { "name": "retinoic acid metabolic process", "id": "GO:0042573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042573", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P400", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P400", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400" }, { "id": "PF00107", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00107" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alcohol dehydrogenase-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 204, "end_pos": 324, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P400", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P400" }, { "id": "PF08240", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alcohol dehydrogenase-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 162, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 192 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 }, { "start_pos": 303, "end_pos": 305 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P508-1", "uniprot_ac": "A0ABI0P508", "uniprot_id": "A0ABI0P508_BOVIN", "mass": { "chemical_mass": 88387.0, "monoisotopic_mass": 88387.0 }, "refseq": {}, "gene_names": [ { "name": "ELMO1", "type": "recommended", "evidence": [ { "id": "A0ABI0P508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508" } ] } ], "protein_names": [ { "name": "Engulfment and cell motility 1", "type": "synonym", "evidence": [ { "id": "A0ABI0P508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.", "evidence": [ { "database": "UniProtKB", "id": "F1MQH0", "url": "https://www.uniprot.org/uniprotkb/F1MQH0#function" }, { "database": "UniProtKB", "id": "ARBA00024863", "url": "https://www.uniprot.org/uniprotkb/ARBA00024863#function" }, { "database": "UniProtKB", "id": "A0ABI0P262", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P262#function" }, { "database": "UniProtKB", "id": "A0ABI0P508", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P508", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ELMO1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508", "locus": { "chromosome": "4", "start_pos": 60450510, "end_pos": 59979396, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003490", "url": "https://www.ensembl.org/id/ENSBTAG00000003490" } ] } } ], "crossref": [ { "id": "ENSBTAG00000003490", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003490", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13359", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13359", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CPHMKDL", "url": "https://omabrowser.org/oma/group/CPHMKDL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MQH0", "url": "https://www.orthodb.org/?gene=F1MQH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12771", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12771", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12771:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12771:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04727", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04727", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26964", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26964", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2029482", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2029482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4420097", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4420097", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8849471", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8849471", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9958810", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958810", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0P262", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P262", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P262-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P262-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P508", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P508-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MQH0", "url": "https://www.uniprot.org/uniprotkb/F1MQH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MQH0-1", "url": "https://www.uniprot.org/uniprotkb/F1MQH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFYITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDVSILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGTDQEIQTYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLGFIQKNDFPQIICVWAKLLSSYLTLWDSMDHSLPGSSLHGILQNHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNCRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN", "length": 767, "header": "tr|A0ABI0P508-1|A0ABI0P508_BOVIN Isoform 1 of Engulfment and cell motility 1 OS=Bos taurus OX=9913 GN=ELMO1 PE=4 SV=1 CANONICAL=A0ABI0P508-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P262-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508/entry#A0ABI0P262-1", "sequence": { "sequence": "MDGPLQTMNTLHCSMLIVQTSISQKRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDVSILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGTDQEIQTYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNCRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN", "length": 687, "header": "tr|A0ABI0P262-1|A0ABI0P262_BOVIN Computationally mapped isoform of Engulfment and cell motility 1 OS=Bos taurus OX=9913 GN=ELMO1 PE=4 SV=1 CANONICAL=A0ABI0P508-1" }, "locus": { "chromosome": "4", "start_pos": 60449307, "end_pos": 60006365, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138436.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138436.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105148.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105148.1" } ] } }, { "isoform_ac": "A0ABI0P508-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508/entry#A0ABI0P508-1", "sequence": { "sequence": "MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFYITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDVSILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGTDQEIQTYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLGFIQKNDFPQIICVWAKLLSSYLTLWDSMDHSLPGSSLHGILQNHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNCRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN", "length": 767, "header": "tr|A0ABI0P508-1|A0ABI0P508_BOVIN Isoform 1 of Engulfment and cell motility 1 OS=Bos taurus OX=9913 GN=ELMO1 PE=4 SV=1 CANONICAL=A0ABI0P508-1" }, "locus": { "chromosome": "4", "start_pos": 60449307, "end_pos": 59979544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144643.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144643.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105914.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105914.1" } ] } }, { "isoform_ac": "F1MQH0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508/entry#F1MQH0-1", "sequence": { "sequence": "MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFYITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDVSILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGTDQEIQTYTIAVINALFLKAPDERRQVGVDSSVDILECPLTEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNCRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN", "length": 742, "header": "tr|F1MQH0-1|A0ABI0P508_BOVIN Computationally mapped isoform of Engulfment and cell motility 1 OS=Bos taurus OX=9913 GN=ELMO1 PE=4 SV=2 CANONICAL=A0ABI0P508-1" }, "locus": { "chromosome": "4", "start_pos": 60449307, "end_pos": 59979544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039193.7", "url": "https://www.ensembl.org/id/ENSBTAT00000039193.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038993.5", "url": "https://www.ensembl.org/id/ENSBTAP00000038993.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-2029482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2029482", "resource": "Reactome", "description": "Regulation of actin dynamics for phagocytic cup formation" }, { "id": "R-BTA-4420097", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4420097", "resource": "Reactome", "description": "VEGFA-VEGFR2 Pathway" }, { "id": "R-BTA-8849471", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8849471", "resource": "Reactome", "description": "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" }, { "id": "R-BTA-9958810", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958810", "resource": "Reactome", "description": "SRC activates STAT3 in a quantitative manner, through Cadherin-11 (CDH11), RAC1 and gp130 (IL6ST)" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SIM4-1", "protein_name": "Engulfment and cell motility 1", "gene_name": "ELMO1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFYITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDVSILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGTDQEIQTYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNCRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTQNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN", "length": 727 }, "evidence": [ { "id": "A0ABI0P508", "url": "https://omabrowser.org/oma/group/A0ABI0P508/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HRA7-1", "protein_name": "Engulfment and cell motility protein 1 isoform X1", "gene_name": "Elmo1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFYITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGTDQEIQTYTIAVINALFLKAPDERRQEMANILAQKQLRYIILTHVIRAQRAINNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAELEPNNSSGSMEKRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMLSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN", "length": 727 }, "evidence": [ { "id": "A0ABI0P508", "url": "https://omabrowser.org/oma/group/A0ABI0P508/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BPU7-1", "protein_name": "Engulfment and cell motility protein 1", "gene_name": "Elmo1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPPSDIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFYITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGTDQEIQTYTIAVINALFLKAPDERRQEMANILAQKQLRYIILTHVIRAQRAINNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN", "length": 727 }, "evidence": [ { "id": "A0ABI0P508", "url": "https://omabrowser.org/oma/group/A0ABI0P508/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92556-1", "protein_name": "Engulfment and cell motility protein 1", "gene_name": "ELMO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFYITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQTYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN", "length": 727 }, "evidence": [ { "id": "A0ABI0P508", "url": "https://omabrowser.org/oma/group/A0ABI0P508/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VKB2-1", "protein_name": "Ced-12", "gene_name": "Ced-12", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIPKKTTVKDSHIVKIAVEREDHIAQLINLDQRHPLASKIQEICNGWSISDHQNYALQFYEPTNRKYVTEKNRNEIKNGSVLQLQYSPSKTACDAMEVLLNGSPQEKALRLKELTSLSTDHTFALEFIKEKGLDTLIKMIEDGGQTNEDILKYSLASFVELMEHGTVSWEVPENSFVARNIEIVRNFQKYPTNCGESALSNLENIVMCSNKHVLVAEDIKLQDILRLLQDVNSPVMRQNAIALLNALFVKADEGRRRTIAQTISAKQFRLALIGNGLGTEMTHQLYVLQTLTLGLLEKRMRMKMNAQDQDAHEKIKELRRIAFDDNTNALNQNDDHIRRGGGSGAGNVNFSQYYKKLGFKCDINPAQDFIETPPGILALDCMVYFARNYTQQYAKIVRENSCRADEHECPFGRTSIELVKVLCDILRIGEPPAEQSGDFQPMFFTHDSPFEEFFCICVITLNRTWKDMRATAEDFSTTFSVVREQIQRTLKGRPENLDDFRNKIALLTYQQITTLRQQERTSKEECDSTASAIVKLKEKISPQILELIKQQRLSFLVEGTHFAKYLRGTRTKDKFWYARLSPNHKVIHYGDCDEKTIPTMEELPKKLPISEIKQLLEGKECPHMKETRIRKSAVNLAFSITFENMEHSTLDFVAPDESIFNYWTDGINALLGQPMVSKQKNEDFDTLLSMEIKLRLLDTEGVDISKDPPPIPEDPENYDFCFES", "length": 724 }, "evidence": [ { "id": "A0ABI0P508", "url": "https://omabrowser.org/oma/group/A0ABI0P508/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P508", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor complex", "id": "GO:0032045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032045", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P508", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P508", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P508", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P508", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508" } ], "pmid": "" }, { "name": "cell motility", "id": "GO:0048870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048870", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P508", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508" } ], "pmid": "" }, { "name": "regulation of vasculogenesis", "id": "GO:2001212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001212", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P508", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P508", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P508" }, { "id": "PS51335", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51335" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ELMO", "eco_id": "ECO_0000259", "start_pos": 319, "end_pos": 532, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 442, "end_pos": 444 }, { "start_pos": 504, "end_pos": 506 }, { "start_pos": 548, "end_pos": 550 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P281-1", "uniprot_ac": "A0ABI0P281", "uniprot_id": "A0ABI0P281_BOVIN", "mass": { "chemical_mass": 165850.0, "monoisotopic_mass": 165850.0 }, "refseq": { "ac": "XP_003586820", "name": "macrophage mannose receptor 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586820" }, "gene_names": [ { "name": "MRC1", "type": "recommended", "evidence": [ { "id": "A0ABI0P281", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281" } ] }, { "name": "MRC1", "type": "synonym", "evidence": [ { "id": "XP_003586820", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586820" } ] } ], "protein_names": [ { "name": "Macrophage mannose receptor 1", "type": "recommended", "evidence": [ { "id": "A0ABI0P281", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281/entry#names_and_taxonomy" } ] }, { "name": "macrophage mannose receptor 1", "type": "synonym", "evidence": [ { "id": "XP_003586820", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586820" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P281", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MRC1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281", "locus": { "chromosome": "13", "start_pos": 32353565, "end_pos": 32240129, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038048", "url": "https://www.ensembl.org/id/ENSBTAG00000038048" } ] } } ], "crossref": [ { "id": "ENSBTAG00000038048", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038048", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00062", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00062", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "787578", "url": "https://www.ncbi.nlm.nih.gov/gene/787578", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000772", "database": 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"https://www.ebi.ac.uk/interpro/entry/IPR036943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:787578", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787578", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WIDKWRV", "url": "https://omabrowser.org/oma/group/WIDKWRV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MWM8", "url": "https://www.orthodb.org/?gene=F1MWM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22803", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22803", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00040", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00040", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1236978", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1236978", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003586820", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586820", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0P281", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P281-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MWM8", "url": "https://www.uniprot.org/uniprotkb/F1MWM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MWM8-1", "url": "https://www.uniprot.org/uniprotkb/F1MWM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPSPLLSLLFLLPVAVQLLDTRPFLIYNEDHKRCVEALSPSAVQTAVCDPNNEAQKFRWVSESQIMSVALKLCLGVPSKTDWVPVTLYACDSRSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDDLCSRGYEAMYTLLGNANGATCAFPFKFENKWYGECTKAGRSDGWLWCGTTTDYDTDRLFGYCPLKFEGSESLWTKDPLTSIYYQINSKAALTWHQARKSCQQQDAELLSITEIHEQTYLTGLTNSLTSGLWIGLNSLNFNSGWQWSGGSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLQCVQKLGYICKKGNTTLNPFVIPSESDVPTNCPSQWWPYAGHCYKIYREEKKIQRDALRACRKEGGDLASIHSIEEFDFIISQLGYEPSDELWIGLNDIKIQMYFEWSDGTPVTFTKWLHGEPSHENNRQEDCAVMKGKDGYWADRACERPLGYICKMKSQAQTPGVVEVEAGCQKGWKRHGFYCYLIGHTLSTFTEANQTCVSEKAYLTTVEDRYEQAFLTSLVGLRPERYFWIGLSDVQHKGTFQWTVEEGVQFTHWNSDMPGRKAGCVAMKTGVAGGLWDVLRCEEKAKFVCKHWAEGVTRPPEPTTTPEPKCPEDWGASSKTSLCFKLFAKGKHEKKTWFESRDFCRALGGDLASINSKEEQQAIWRLVTASGSYHELFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPGMSWNDINCEHLNNWICQIRKGQTPKPEPTPAPHDNLPVTDDGWVIYKDYQYYFSKEKATMDKAREFCKRNFGDLVSIRSESEKKFLWKYVNRNDVQPAYFIGLLISLDKKFIWMDGSKVDYVAWATGEPNFANDDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSINATVVPTTVSVPGGCKEGWNFYNHKCFKIFGFVEEERKNWQEARKDCIGFGGNLASIYSEKEQAFLTYHMKNSTFNAWTGLNDINSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVVIGGNTRDAGKWMDDTCDSKRGYICQTHPDRSLPSSPTTIPTDGFIKYGESSYSLMKLKLQWHEADDYCKMHTSHIASILDPYSNAFAWMHMQTLNEPVWIALNSNLTNNDYIWTDKWRVRYTNWAPDEPRLKSACAYMDLDGYWKTAQCNESFYFLCKRSDEIPATEPPQLPGRCPETEHSAWIPFHGHCYYIESSFTRNWGQASLECLRMGSSLVTIESAAELSFLSYRVEPLQSKTNFWIGLYRNVEGMWVWINNNPLSFVNWKTGDPSGERNDCVTLYASSGLWSNIHCSSYKGYICKRPKIVDAEPTHTLITTKADPRKMEPSKPSSSATGVVVIVVLLIIMGAGFAVYFFYKKRRVHLPREDAFENTLYFNSGSSPGTNDTKDLMGNIEQNEHAAI", "length": 1455, "header": "tr|A0ABI0P281-1|A0ABI0P281_BOVIN Isoform 1 of Macrophage mannose receptor 1 OS=Bos taurus OX=9913 GN=MRC1 PE=4 SV=1 CANONICAL=A0ABI0P281-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P281-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281/entry#A0ABI0P281-1", "sequence": { "sequence": "MRPSPLLSLLFLLPVAVQLLDTRPFLIYNEDHKRCVEALSPSAVQTAVCDPNNEAQKFRWVSESQIMSVALKLCLGVPSKTDWVPVTLYACDSRSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDDLCSRGYEAMYTLLGNANGATCAFPFKFENKWYGECTKAGRSDGWLWCGTTTDYDTDRLFGYCPLKFEGSESLWTKDPLTSIYYQINSKAALTWHQARKSCQQQDAELLSITEIHEQTYLTGLTNSLTSGLWIGLNSLNFNSGWQWSGGSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLQCVQKLGYICKKGNTTLNPFVIPSESDVPTNCPSQWWPYAGHCYKIYREEKKIQRDALRACRKEGGDLASIHSIEEFDFIISQLGYEPSDELWIGLNDIKIQMYFEWSDGTPVTFTKWLHGEPSHENNRQEDCAVMKGKDGYWADRACERPLGYICKMKSQAQTPGVVEVEAGCQKGWKRHGFYCYLIGHTLSTFTEANQTCVSEKAYLTTVEDRYEQAFLTSLVGLRPERYFWIGLSDVQHKGTFQWTVEEGVQFTHWNSDMPGRKAGCVAMKTGVAGGLWDVLRCEEKAKFVCKHWAEGVTRPPEPTTTPEPKCPEDWGASSKTSLCFKLFAKGKHEKKTWFESRDFCRALGGDLASINSKEEQQAIWRLVTASGSYHELFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPGMSWNDINCEHLNNWICQIRKGQTPKPEPTPAPHDNLPVTDDGWVIYKDYQYYFSKEKATMDKAREFCKRNFGDLVSIRSESEKKFLWKYVNRNDVQPAYFIGLLISLDKKFIWMDGSKVDYVAWATGEPNFANDDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSINATVVPTTVSVPGGCKEGWNFYNHKCFKIFGFVEEERKNWQEARKDCIGFGGNLASIYSEKEQAFLTYHMKNSTFNAWTGLNDINSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVVIGGNTRDAGKWMDDTCDSKRGYICQTHPDRSLPSSPTTIPTDGFIKYGESSYSLMKLKLQWHEADDYCKMHTSHIASILDPYSNAFAWMHMQTLNEPVWIALNSNLTNNDYIWTDKWRVRYTNWAPDEPRLKSACAYMDLDGYWKTAQCNESFYFLCKRSDEIPATEPPQLPGRCPETEHSAWIPFHGHCYYIESSFTRNWGQASLECLRMGSSLVTIESAAELSFLSYRVEPLQSKTNFWIGLYRNVEGMWVWINNNPLSFVNWKTGDPSGERNDCVTLYASSGLWSNIHCSSYKGYICKRPKIVDAEPTHTLITTKADPRKMEPSKPSSSATGVVVIVVLLIIMGAGFAVYFFYKKRRVHLPREDAFENTLYFNSGSSPGTNDTKDLMGNIEQNEHAAI", "length": 1455, "header": "tr|A0ABI0P281-1|A0ABI0P281_BOVIN Isoform 1 of Macrophage mannose receptor 1 OS=Bos taurus OX=9913 GN=MRC1 PE=4 SV=1 CANONICAL=A0ABI0P281-1" }, "locus": { "chromosome": "13", "start_pos": 32352561, "end_pos": 32240233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142973.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142973.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105586.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105586.1" } ] } }, { "isoform_ac": "F1MWM8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281/entry#F1MWM8-1", "sequence": { "sequence": "MRPSPLLSLLFLLPVAVQLLDTRPFLIYNEDHKRCVEALSPSAVQTAVCDPNNEAQKFRWVSESQIMSVALKLCLGVPSKTDWVPVTLYACDSRSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDDLCSRGYEAMYTLLGNANGATCAFPFKFENKWYGECTKAGRSDGWLWCGTTTDYDTDRLFGYCPLKFEGSESLWTKDPLTSIYYQINSKAALTWHQARKSCQQQDAELLSITEIHEQTYLTGLTNSLTSGLWIGLNSLNFNSGWQWSGGSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLQCVQKLGYICKKGNTTLNPFVIPSESDVPTNCPSQWWPYAGHCYKIYREEKKIQRDALRACRKEGGDLASIHSIEEFDFIISQLGYEPSDELWIGLNDIKIQMYFEWSDGTPVTFTKWLHGEPSHENNRQEDCAVMKGKDGYWADRACERPLGYICKMKSQAQTPGVVEVEAGCQKGWKRHGFYCYLIGHTLSTFTEANQTCVSEKAYLTTVEDRYEQAFLTSLVGLRPERYFWIGLSDVQHKGTFQWTVEEGVQFTHWNSDMPGRKAGCVAMKTGVAGGLWDVLRCEEKAKFVCKHWAEGVTRPPEPTTTPEPKCPEDWGASSKTSLCFKLFAKGKHEKKTWFESRDFCRALGGDLASINSKEEQQAIWRLVTASGSYHELFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPGMSWNDINCEHLNNWICQIRKDLPVTDDGWVIYKDYQYYFSKEKATMDKAREFCKRNFGDLVSIRSESEKKFLWKYVNRNDVQPAYFIGLLISLDKKFIWMDGSKVDYVAWATGEPNFANDDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSINATVVPTTVSVPGGCKEGWNFYNHKCFKIFGFVEEERKNWQEARKDCIGFGGNLASIYSEKEQAFLTYHMKNSTFNAWTGLNDINSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVVIGGNTRDAGKWMDDTCDSKRGYICQTHPDRSLPSSPTTIPTDGFIKYGESSYSLMKLKLQWHEADDYCKMHTSHIASILDPYSNAFAWMHMQTLNEPVWIALNSNLTNNDYIWTDKWRVRYTNWAPDEPRLKSACAYMDLDGYWKTAQCNESFYFLCKRSDEIPATEPPQLPGRCPETEHSAWIPFHGHCYYIESSFTRNWGQASLECLRMGSSLVTIESAAELSFLSYRVEPLQSKTNFWIGLYRNVEGMWVWINNNPLSFVNWKTGDPSGERNDCVTLYASSGLWSNIHCSSYKGYICKRPKIVDAEPTHTLITTKADPRKMEPSKPSSSATGVVVIVVLLIIMGAGFAVYFFYKKRRVHLPREDAFENTLYFNSGSSPGTNDTKDLMGNIEQNEHAAI", "length": 1441, "header": "tr|F1MWM8-1|A0ABI0P281_BOVIN Computationally mapped isoform of Macrophage mannose receptor 1 OS=Bos taurus OX=9913 GN=MRC1 PE=4 SV=3 CANONICAL=A0ABI0P281-1" }, "locus": { "chromosome": "13", "start_pos": 32352561, "end_pos": 32240233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054341.5", "url": "https://www.ensembl.org/id/ENSBTAT00000054341.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051181.3", "url": "https://www.ensembl.org/id/ENSBTAP00000051181.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 790, "start_aa": "Thr", "end_pos": 790, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr790", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:787578", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787578", "resource": "KEGG Pathway" }, { "id": "R-BTA-1236978", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1236978", "resource": "Reactome", "description": "Cross-presentation of soluble exogenous antigens (endosomes)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4INM0-1", "protein_name": "Macrophage mannose receptor 1", "gene_name": "mrc1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRTFDNPLFVLLFLKIALQLSSQTDTSYFLIYNEDHNRCVNAVSATVLQTAPCDISSEGQRFRWVSSSQIISLSFKLCLGAQNIKDWVKIILVPCNALSPLQTWECKNETLFGLKGQPLHMNYGNRNEQNMMLYKGSGIWSRWQVYGTKDDLCSHGNQEIYTIGGNSFGKPCQFPFKFADKLYAECTTEGRSDGQLWCSTDTDYDTDKKWGFCPTKTSSGWDSDPVTGVLYQRNVQSILTWHQARTSCQQQEADLLSITELHEQSYISGLTNTFGSALWIGLNSLDFESGWQWSNGNPFRYLNWAPGHPSLEPGLTCAALNAGKASKWESMACNKKLGYICRKGNSTDNTPPPGKDQPNFCPAAWVPYAGNCYYLQRTKKMWNDALAACHREGANLASIHNIEEHSFIISQSGYLPTDELWIGLNDQKTQNLFEWSDRTHVTFTTWLVGEPSHFINRLEDCVLIKGKDGKWADHACEMERGYICKKKSSSKPEGAPEVVSLGCQAGWVRYGSYCYMSAIESKTFNEAKQICEQTGANLVDVASRYENAFLISLVGLRPEKYFWIGLSNTESPESFRWSNSDKVKFTHFNVGMPEKHRGCVAMLTGTSAGLWDVLDCNSKQKYICKKMAEGVTTTQIPPTTQPLSCPVGWTKKDPRNCIQIYSRPKEQKKTWFEARDYCKAIGGDLASFHSQKQINNLQYGMGETAWIGFNLLNINSGFVWTDGTPSDFENWSFGEPNNHNNQELCTESSFYYGRKWNDRDCEAYNDWICQIAIGTTPKSPPTTVTQVEYNKTSDGWIQYNDSQYFINEESLPMEDARSFCKKNNGDLVVITGQTERKFVWKQISRGSENQYYIGMIVNLDKSFNWVDGSPVVYTSWDQNEPNFANNDENCVTIYKSMGFWNDINCGVPLPSICKRSSNFINSTLPLPTVRPGGCSPEWTIFQGSCYKLFQNKMTWHDARNLCISHGGNLVSILTHEEQAFLTTLMLDSVDDIWIGFNDVNWEMRFLWTDGKGVSYTNWAKGVPSSMPDGPSRMYEFGSENYDCVVMLRSPEKMTGMWKVQMCGDQQGFICKRKTDTQLIRPVTTAAPQHFFTLGNDSYKVQKEKMSWDEARRQCKASDADLASVRNSISQAYTILTVSKLKEPLWIGLNSNLTSGQYRWVDNWLLSYSRWATGEPKNNLACVYIDTDGRWKTATCNNTYYSLCKQSTDIAPTDPPQMPGNCPESKKRKTWIPFRGHCYAFMSNSENWAHATVECIRIGGSLVSIEDPKESHFIQRNVELMQDGVRSFWIGMHRSYMGDWMWIDNAVVDYTNWRTQVTNNAGHCVEIQSSSGLWNAVNCNSYKPYICKTEKVVPPTKKPLVPLAVVDAGPHSSAGIVVGVVLVIIAVAGLATFLFLKRIPRPAIGECTFDNRLYINSDLTQSPTTIDTKGLVANIEQNEHA", "length": 1440 }, "evidence": [ { "id": "A0ABI0P281", "url": "https://omabrowser.org/oma/group/A0ABI0P281/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8C2QK77-1", "protein_name": "Macrophage mannose receptor 1", "gene_name": "Mrc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRLPLLLAFIFVIPVTVPLLDTRQFLIYNEDHKRCVDAISASSVQTSTCNTEAESQKFRWVSESQVMSIAFKLCLGVSSKTDWASVTLYACDSKSEFQKWECKNDTLFGLKGIDLYFNYGNKQEKNIKLYKGSGLWSRWKVYGTKDDLCSRGYEAMYSLLGNANGAICAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLYGFCPLQFEGSERLWNKDPLTGILYQINSKSALTWHQARESCKQQNAELLSVTEIHEQTYLTGLTSSLSSGLWIGLNSLSFNSGWQWSGGSPFRYLNWLPGSPSSEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNNTLNPFIIPSESDIPTGCPSQWWPYAGHCYKIYREEKKIQRYALQACRKEGGDLASIHSIEEFDFIFSQLGYEPQDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRACEQPLGYICKMASQAHAPAPEEAEKGCRKGWKRHGFYCYLIGHTPLTFGDANQTCTNEKAYLTTVEDRYEQAFLTSLVGLRPEKYFWTGLSDVQNKGSFQWTVEEPVQFTHWNADMPGRKTGCVAMKTGVAGGLWDILKCEEKAKFVCKHWAEGVTRPPEPTTTPEPKCPEDWGTTSKTSMCFKLYAKGKHEKKTWFESRDFCRAMGGELASIKNKDEQQVIWRLITTSGSYHELFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPGMSWNDINCEHLSNWICQIQKGKTLLPEPTPAPQDNPPVTADGWVIYKDHQYFFSKEKETMDNARAFCKKNFGDLATIKSESEKKFLWKYINKNGGQSPYFIGLLISLDKKFIWMDGSKVDFVAWATGEPNFANDDENCVTMYTNSGFWNDINCGFPNNFICQRHNSSINATAIPTTPRTPGGCKEGWHLYNNKCFKIFGFAEEEKKNWQDARETCKGFKGNLVSIQNVKEQAFITYHMKDSTFNAWTGLNDINSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVVIGGKSREAGSWMDDTCDSKQGYICQTQPDPSLPVSPTTIPTDGFVKYGKSSYSLIKLKSPWHEAEQYCKDHDSLLASILDPYSNAFAWMKMYLFNVPIWIALNSNLTNNEYTWIDKWRVRYTNWGADEPKLKSACVYMDVDGYWKTSYCNESFYFLCKKSDETPATEPPQLPGRCPESEQTAWIPFHGHCYYIESSFTRNWGQASLECLRMGASLASIETAAESSFLSYRAEPLKSKTNFWIGMFRNVEGKWLWLNNNPVSFVNWNTGDPSGERNDCVVLSSSSGFWNNIHCTSYKGFICKMPKIIDPVTTHSSSITTKADQRKMDPQPKGSSRAAGVVIVVLLILMGAGVAAYFLYKKRRALHIPQEATFENTLYFDSHQTPGTSDTKDLMGNIEQNEHVVI", "length": 1457 }, "evidence": [ { "id": "A0ABI0P281", "url": "https://omabrowser.org/oma/group/A0ABI0P281/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZD31-1", "protein_name": "Macrophage mannose receptor 1", "gene_name": "Mrc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHTLWAMRLPLLLAFISVIPVAVQLLDSRQFLIYNEDHKRCVDALSAISVQTATCNPEAESQKFRWVSESQIMSVAFKLCLGVPSKTDWASVTLYACDSKSEFQKWECKNDTLFGIKGTELYFNYGNRQEKNIKLYKGSGLWSRWKVYGTTDDLCSRGYEAMYSLLGNANGAVCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGFCPLQFEGSKRLWNTDPLTGILYQINSKSALTWHQARASCKQQNAELLSVTEIHEQMYLTGLTSSLTSGLWIGLNSLSLSTGWQWAGGSPFRYLNWLPGSPSSEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNNTLNPFIIPSESDVPTACPNQWWPYAGHCYRIYREEKKIQKYALQACRKEGGDLASIHSIEEFDFIFSQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLPGEPSHENNRQEDCVVMKGKDGYWADRACEQPLGYICKMVSQIHTVIPEGAEKGCRKGWKRHGFYCYLIGSTLSTFADANQTCTNEKAYLTTVEDRYEQAFLTSLVGLRPEKYFWTGLSDVQNKGTFRWTVDEQVQFTHWNADMPGRKAGCVAMKTGVAGGLWDVLSCEEKAKFVCKHWAEGVTRPPEPTTTPEPKCPEDWGTTSKTSMCFKLYAKGKHEKKTWFESRDFCKAIGGELASIKSKDEQQVIWRLITSSGSYHELFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPGMSWNDINCEHLNNWICQIQKGKTLLPEPTPAPQDNPPVTADGWVIYKDYQYYFSKEKETMDNARAFCKKNFGDLATIKSESEKKFLWKYINKNGGQSPYFIGLLISLDKKFIWMDGSKVDFVAWATGEPNFANDDENCVTMYTNSGFWNDINCGYPNNFICQRHNSSINATAMPTTPPTPGGCKEGWHLYNNKCFKIFGFAEEEKKTWKEARKACIGLKGNLVSIENAKEQAFVTYHMRDSTFNAWTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDVDCVVVIGGNSREAGTWMDSTCDSKQGYICQTQTDPSVPISPTTAPKDGFVKYGKSSYALMKLKSPWHEAEKYCKDRTSLLASILDPYSNAFAWMKMHPFNVPIWIALNSNLTNNEYTWTDKWRVRYTNWGTDEPKLKSACVYMDVDGYWKTSYCNESFYFLCKKSDEIPATEPPQLPGKCPESEQTAWIPFHGHCYYIESSFTRSWGQASLECLRMGASLVSIETAAESSFLSYRVEPLKSKTNFWIGMFRNVEGKWLWLNDNPVSFVNWKTGDPSGERNDCVVLSSSSGLWNNIHCTSYKGFICKMPKIIDPVTTHSSITTKADQRKMDPQPKGSSKAAGVVIVVLLIVIGAGVAAYFFYKKRRVLHIPQEATFENTLYFNSNPSPGTSDTKDLVGNIEQNEHAVI", "length": 1463 }, "evidence": [ { "id": "A0ABI0P281", "url": "https://omabrowser.org/oma/group/A0ABI0P281/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22897-1", "protein_name": "Macrophage mannose receptor 1", "gene_name": "MRC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLPLLLVFASVIPGAVLLLDTRQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNTTLNSFVIPSESDVPTHCPSQWWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYICKMKSRSQGPEIVEVEKGCRKGWKKHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTHWNSDMPGRKPGCVAMRTGIAGGLWDVLKCDEKAKFVCKHWAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQKGQTPKPEPTPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNAFAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLDGYWKTAHCNESFYFLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRNWGQASLECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNFWIGLFRNVEGTWLWINNSPVSFVNWNTGDPSGERNDCVALHASSGFWSNIHCSSYKGYICKRPKIIDAKPTHELLTTKADTRKMDPSKPSSNVAGVVIIVILLILTGAGLAAYFFYKKRRVHLPQEGAFENTLYFNSQSSPGTSDMKDLVGNIEQNEHSVI", "length": 1456 }, "evidence": [ { "id": "A0ABI0P281", "url": "https://omabrowser.org/oma/group/A0ABI0P281/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61830-1", "protein_name": "Macrophage mannose receptor 1", "gene_name": "Mrc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 1456 }, "evidence": [ { "id": "A0ABI0P281", "url": "https://omabrowser.org/oma/group/A0ABI0P281/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P281", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281" } ], "pmid": "" }, { "name": "D-mannose binding", "id": "GO:0005537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005537", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P281", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P281", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P281", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P281", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P281", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P281", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P281", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P281" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1001, "end_pos": 1003, "annotation": "n_glycosylation_sequon" }, { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1159, "end_pos": 1161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1204, "end_pos": 1206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1438, "end_pos": 1440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": 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"snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P1G2-1", "uniprot_ac": "A0ABI0P1G2", "uniprot_id": "A0ABI0P1G2_BOVIN", "mass": { "chemical_mass": 27968.0, "monoisotopic_mass": 27968.0 }, "refseq": {}, "gene_names": [ { "name": "RAB7A", "type": "recommended", "evidence": [ { "id": "A0ABI0P1G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2" } ] } ], "protein_names": [ { "name": "Ras-related protein Rab-7a", "type": "recommended", "evidence": [ { "id": "A0ABI0P1G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RAB7A", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2", "locus": { "chromosome": "22", "start_pos": 59192424, "end_pos": 59207552, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010193", "url": "https://www.ensembl.org/id/ENSBTAG00000010193" } ] } } ], "crossref": [ { "id": "ENSBTAG00000010193", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010193", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01862", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01862", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M3K7", "url": "https://www.orthodb.org/?gene=A0A3Q1M3K7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MJQ1", "url": "https://www.orthodb.org/?gene=F1MJQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47981:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47981:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1M3K7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3K7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3K7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQJ3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZX6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZX6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ16", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZ16-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZ16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1G2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1G2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MJQ1", "url": "https://www.uniprot.org/uniprotkb/F1MJQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MJQ1-1", "url": "https://www.uniprot.org/uniprotkb/F1MJQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVPGERASALGDLEASPHWEGQALFSCETDSPSRLHTSELVCSANLPDLLWFFSNFRVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRTKPSAEGCSC", "length": 247, "header": "tr|A0ABI0P1G2-1|A0ABI0P1G2_BOVIN Isoform 1 of Ras-related protein Rab-7a OS=Bos taurus OX=9913 GN=RAB7A PE=1 SV=1 CANONICAL=A0ABI0P1G2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M3K7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2/entry#A0A3Q1M3K7-1", "sequence": { "sequence": "MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQVGVCSIGASGFGPSACTSPRGLSVQPSAPPGPEPRPGRLGLHLSPQALCAARGGGGPLRAALSRRP", "length": 242, "header": "tr|A0A3Q1M3K7-1|A0ABI0P1G2_BOVIN Computationally mapped isoform of Ras-related protein Rab-7a OS=Bos taurus OX=9913 GN=RAB7A PE=1 SV=1 CANONICAL=A0ABI0P1G2-1" }, "locus": { "chromosome": "22", "start_pos": 59203029, "end_pos": 59194814, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073535.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073535.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064734.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064734.1" } ] } }, { "isoform_ac": "A0AAA9SQJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2/entry#A0AAA9SQJ3-1", "sequence": { "sequence": "MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQETEVELYNEFPEPIKLDKNDRTKPSAEGCSC", "length": 91, "header": "tr|A0AAA9SQJ3-1|A0ABI0P1G2_BOVIN Computationally mapped isoform of Ras-related protein Rab-7a OS=Bos taurus OX=9913 GN=RAB7A PE=1 SV=1 CANONICAL=A0ABI0P1G2-1" }, "locus": { "chromosome": "22", "start_pos": 59203029, "end_pos": 59192979, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089982.1", "url": 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"url": "https://www.ensembl.org/id/ENSBTAP00000089835.2" } ] } }, { "isoform_ac": "A0ABI0NZ16-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2/entry#A0ABI0NZ16-1", "sequence": { "sequence": "YADLPEDRLPVCSAGDSVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRTKPSAEGCSC", "length": 206, "header": "tr|A0ABI0NZ16-1|A0ABI0P1G2_BOVIN Computationally mapped isoform of Ras-related protein Rab-7a OS=Bos taurus OX=9913 GN=RAB7A PE=1 SV=1 CANONICAL=A0ABI0P1G2-1" }, "locus": { "chromosome": "22", "start_pos": 59201819, "end_pos": 59192979, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142158.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142158.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106403.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106403.1" } ] } }, { "isoform_ac": "A0ABI0P1G2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2/entry#A0ABI0P1G2-1", "sequence": { "sequence": "MSVPGERASALGDLEASPHWEGQALFSCETDSPSRLHTSELVCSANLPDLLWFFSNFRVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRTKPSAEGCSC", "length": 247, "header": "tr|A0ABI0P1G2-1|A0ABI0P1G2_BOVIN Isoform 1 of Ras-related protein Rab-7a OS=Bos taurus OX=9913 GN=RAB7A PE=1 SV=1 CANONICAL=A0ABI0P1G2-1" }, "locus": { "chromosome": "22", "start_pos": 59201040, "end_pos": 59192979, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150892.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150892.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106836.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106836.1" } ] } }, { "isoform_ac": "F1MJQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2/entry#F1MJQ1-1", "sequence": { "sequence": "MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRTKPSAEGCSC", "length": 134, "header": "tr|F1MJQ1-1|A0ABI0P1G2_BOVIN Computationally mapped isoform of Ras-related protein Rab-7a OS=Bos taurus OX=9913 GN=RAB7A PE=1 SV=2 CANONICAL=A0ABI0P1G2-1" }, "locus": { "chromosome": "22", "start_pos": 59203029, "end_pos": 59192979, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013451.5", "url": "https://www.ensembl.org/id/ENSBTAT00000013451.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013451.4", "url": "https://www.ensembl.org/id/ENSBTAP00000013451.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": 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"total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1G2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1G2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P1V8-1", "uniprot_ac": "A0ABI0P1V8", "uniprot_id": "A0ABI0P1V8_BOVIN", "mass": { "chemical_mass": 133783.0, "monoisotopic_mass": 133783.0 }, "refseq": {}, "gene_names": [ { "name": "JAK1", "type": "recommended", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] } ], "protein_names": [ { "name": "Tyrosine-protein kinase", "type": "recommended", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8/entry#names_and_taxonomy" } ] }, { "name": "2.7.10.2", "type": "synonym", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Kinase partner for the type I interferon receptor IFNAR2. In response to interferon-binding to IFNAR1-IFNAR2 heterodimer, phosphorylates and activates its binding partner IFNAR2, creating docking sites for STAT proteins. Directly phosphorylates STAT proteins but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8#function" }, { "database": "UniProtKB", "id": "ARBA00054436", "url": "https://www.uniprot.org/uniprotkb/ARBA00054436#function" }, { "database": "UniProtKB", "id": "F1N0D6", "url": "https://www.uniprot.org/uniprotkb/F1N0D6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "JAK1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8", "locus": { "chromosome": "3", 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"categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": 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"description": "Inactivation of CSF3 (G-CSF) signaling" }, { "id": "R-BTA-9732724", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9732724", "resource": "Reactome", "description": "IFNG signaling activates MAPKs" }, { "id": "R-BTA-9931295", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9931295", "resource": "Reactome", "description": "PD-L1(CD274) glycosylation and translocation to plasma membrane" }, { "id": "R-BTA-9958825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958825", "resource": "Reactome", "description": "Activation of STAT3 by cadherin engagement" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ], "pmid": "" }, { "name": "growth hormone receptor binding", "id": "GO:0005131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005131", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ], "pmid": "" }, { "name": "growth hormone receptor signaling pathway via JAK-STAT", "id": "GO:0060397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060397", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1V8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1138, "end_pos": 1140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 769, "end_pos": 771, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MWN2-1", "A0AAF6DMB3-1", "E1BI01-1", "A0AAA9TQL1-1", "F1MQH2-1", "F1N781-1", "F6QXU6-1", "A0A3Q1MKW9-1", "A0A3Q1M0U5-1", "F6S1J8-1", "A5D791-1", "F1N664-1", "E1BMP9-1", "F1MS00-1", "P43481-1", "A0A3Q1LR28-1", "A0A3Q1LVP1-1", "Q06807-1", "A0AAA9TD48-1", "Q5E9X2-1", "Q05688-1", "Q17R13-1", "E1BG90-1", "Q0VBZ0-1", "F1N758-1", "A0A3Q1LTC6-1", "A0A3Q1LNU2-1", "F1N1Q0-1", "A0A3Q1MHB0-1", "A0AAA9SN20-1", "A0AAA9TMY2-1", "A0A3Q1LI98-1", "E1BJ31-1", "A0A3Q1LRR9-1", "F1MX49-1", "A0A3Q1MHG9-1", "A0JNB0-1", "E1BER5-1", "E1BIM8-1", "E1BNE0-1", "A0A3Q1LT44-1", "A0A3Q1MJG0-1", "F1MII5-1", "F1N0D3-1", "F1N261-1", "F1N759-1", "F1N780-1", "F1MC14-1", "F1N3R6-1", "A0ABI0P1V8-1", "A0A3Q1LUE0-1", "F1MFH7-1", "F1MNW2-1", "A0AAA9SPC9-1", "F1N381-1", "F1MS29-1", "G1K218-1", "Q4TVR5-1", "A0AAA9SXH6-1", "E1BJS9-1", "A0AAA9SBR4-1", "F1MKR1-1", "F1MN51-1", "E1BCZ6-1", "E1BEL4-1", "F1MCX4-1", "F1N6J0-1", "Q3SZJ2-1", "Q769I5-1", "Z4YHD9-1", "Q06805-1", "Q3SX21-1", "A0A3Q1MAM7-1", "E1BPB5-1", "A0A3Q1MF99-1", "A0AAA9SA57-1", "A0AAA9TAT1-1", "A0AAA9THG2-1", "F1MC23-1", "A0AAA9SVL9-1", "F1MRU0-1", "A0AAA9T042-1", "E1BKP7-1", "E1BNA8-1", "F1ML02-1", "E1BPI3-1", "A0AAA9SW95-1", "G3X680-1", "A0AAA9TRY4-1", "A0A3Q1MEZ6-1", "E1B9H4-1", "E1B6X6-1", "E1B9Q2-1", "E1BPP1-1", "F1N6H6-1", "A0ABI0NRQ5-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "R-BTA-1067651", "name": "IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-1067651", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1067651" } ] }, { "id": "R-BTA-1067659", "name": "Assembly of hexameric IL-6 receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-1067659", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1067659" } ] }, { "id": "R-BTA-1067688", "name": "IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-1067688", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1067688" } ] }, { "id": "R-BTA-109857", "name": "MAP2K1 binds MAPK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "F1N339-1", "E1B8P9-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-109857", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-109857" } ] }, { "id": "R-BTA-1112510", "name": "IL6ST is tyrosine phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-1112510", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1112510" } ] }, { "id": "R-BTA-1112514", "name": "JAK activation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-1112514", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1112514" } ] }, { "id": "R-BTA-1112565", "name": "Tyrosine phosphorylated IL6ST binds STAT1,STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-1112565", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1112565" } ] }, { "id": "R-BTA-1112602", "name": "Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-1112602", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1112602" } ] }, { "id": "R-BTA-1112604", "name": "Phosphorylated STATs are released", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-1112604", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1112604" } ] }, { "id": "R-BTA-1112690", "name": "PTPN11 binds CBL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S497-1", "A0AAA9SXH6-1", "F1MCX4-1", "F1N339-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-1112690", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1112690" } ] }, { "id": "R-BTA-1112703", "name": "PTPN11 is phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "F1N339-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-1112703", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1112703" } ] }, { "id": "R-BTA-1112708", "name": "PTPN11 binds p-Y759-IL6ST", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "F1N339-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-1112708", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1112708" } ] }, { "id": "R-BTA-1112727", "name": "Serine phosphorylation of STATs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-1112727", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1112727" } ] }, { "id": "R-BTA-1112755", "name": "SOCS3 binds IL6ST", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-1112755", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1112755" } ] }, { "id": "R-BTA-1169406", "name": "ISGylation of host proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5PJC4-1", "A0ABI0NX25-1", "A2VEA3-1", "E1B8P9-1", "A0ABI0P1V8-1", "A0A3Q1MAR8-1" ], "evidence": [ { "id": "R-BTA-1169406", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1169406" } ] }, { "id": "R-BTA-1295540", "name": "IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-1295540", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1295540" } ] }, { "id": "R-BTA-1678841", "name": "Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0NX25-1", "E1B8P9-1", "A0ABI0P1V8-1", "A0A3Q1MAR8-1" ], "evidence": [ { "id": "R-BTA-1678841", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1678841" } ] }, { "id": "R-BTA-448427", "name": "Interleukin-27 binds Interleukin-27 receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-448427", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-448427" } ] }, { "id": "R-BTA-448480", "name": "IL22 binds IL22RA1:JAK1 receptor complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-448480", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-448480" } ] }, { "id": "R-BTA-448661", "name": "IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-448661", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-448661" } ] }, { "id": "R-BTA-448708", "name": "IL24 binds to IL22RA1:JAK1:IL20RB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-448708", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-448708" } ] }, { "id": "R-BTA-448728", "name": "IL19 binds IL20RA:JAK1:IL20RB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-448728", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-448728" } ] }, { "id": "R-BTA-448744", "name": "IL20RA binds IL20RB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-448744", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-448744" } ] }, { "id": "R-BTA-449115", "name": "IL15:IL15RA binds IL2RB:JAK1 and IL2RG:JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-449115", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-449115" } ] }, { "id": "R-BTA-449803", "name": "IL10 dimer binds IL10RA:JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-449803", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-449803" } ] }, { "id": "R-BTA-449811", "name": "IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-449811", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-449811" } ] }, { "id": "R-BTA-449958", "name": "IL7:IL7R:JAK1 binds IL2RG:JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-449958", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-449958" } ] }, { "id": "R-BTA-449978", "name": "IL7 binds IL7R:JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-449978", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-449978" } ] }, { "id": "R-BTA-450027", "name": "Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-450027", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-450027" } ] }, { "id": "R-BTA-450063", "name": "Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-450063", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-450063" } ] }, { "id": "R-BTA-451900", "name": "IL2RB binds JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-451900", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-451900" } ] }, { "id": "R-BTA-451942", "name": "Within the IL-2R complex JAK3 phosphorylates JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-451942", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-451942" } ] }, { "id": "R-BTA-452091", "name": "Phosphorylation of IL2RB Y338 enables SHC recruitment", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-452091", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-452091" } ] }, { "id": "R-BTA-452097", "name": "Recruited STAT5 is phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-452097", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-452097" } ] }, { "id": "R-BTA-452100", "name": "SHC1 bound to IL2 receptor is phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-452100", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-452100" } ] }, { "id": "R-BTA-452108", "name": "Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-452108", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-452108" } ] }, { "id": "R-BTA-452122", "name": "JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-452122", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-452122" } ] }, { "id": "R-BTA-453104", "name": "Phosphorylated SHC1 recruits GRB2:GAB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-453104", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-453104" } ] }, { "id": "R-BTA-453111", "name": "Phosphorylated SHC recruits GRB2:SOS1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-453111", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-453111" } ] }, { "id": "R-BTA-508247", "name": "Gab2 binds the p85 subunit of Class 1A PI3 kinases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P32871-1", "A0AAA9SXH6-1", "E1BEL4-1", "F1MYM3-1", "E1BE66-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-508247", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-508247" } ] }, { "id": "R-BTA-508282", "name": "SYK is a substrate for JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0A3Q1MHG9-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-508282", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-508282" } ] }, { "id": "R-BTA-508292", "name": "SYK binds IL2RB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0A3Q1MHG9-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-508292", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-508292" } ] }, { "id": "R-BTA-5672965", "name": "RAS GEFs promote RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LUE0-1", "F1N758-1", "A0AAA9SXH6-1", "E1BEL4-1", "A0A3Q1LMP2-1", "A0AAA9SBR4-1", "F1MN51-1", "Q3MHJ9-1", "Z4YHD9-1", "F1MX49-1", "F1MRU0-1", "Q06807-1", "Q2HJF7-1", "E1BPA0-1", "A0A3Q1MHB0-1", "P43481-1", "A0JNB0-1", "F1MS00-1", "A0ABI0P1V8-1", "F1N759-1", "F1MNW2-1", "A0AAA9TAT1-1" ], "evidence": [ { "id": "R-BTA-5672965", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5672965" } ] }, { "id": "R-BTA-5696482", "name": "CTF1 binds LIFR:JAKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-5696482", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5696482" } ] }, { "id": "R-BTA-6783524", "name": "OSM,LIF,CTF1 receptor complex binds gp130", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6783524", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6783524" } ] }, { "id": "R-BTA-6783530", "name": "gp130:JAKs bind CNTFR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6783530", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6783530" } ] }, { "id": "R-BTA-6783552", "name": "OSM binds LIFR:JAKs,OSMR:JAKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6783552", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6783552" } ] }, { "id": "R-BTA-6783556", "name": "LIFR:JAKs bind gp130:JAKs:CNTFR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6783556", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6783556" } ] }, { "id": "R-BTA-6783681", "name": "LIF binds LIFR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6783681", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6783681" } ] }, { "id": "R-BTA-6784006", "name": "STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6784006", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6784006" } ] }, { "id": "R-BTA-6784189", "name": "JAKs bind LIFR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6784189", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6784189" } ] }, { "id": "R-BTA-6784319", "name": "JAK1,TYK2 phosphorylate JAK1,TYK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6784319", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6784319" } ] }, { "id": "R-BTA-6784323", "name": "IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6784323", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6784323" } ] }, { "id": "R-BTA-6784324", "name": "p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6784324", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6784324" } ] }, { "id": "R-BTA-6784791", "name": "p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6784791", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6784791" } ] }, { "id": "R-BTA-6785165", "name": "p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6785165", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6785165" } ] }, { "id": "R-BTA-6786050", "name": "IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6786050", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6786050" } ] }, { "id": "R-BTA-6786058", "name": "JAK1 binds IL4R in IL4-bound IL4R1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6786058", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6786058" } ] }, { "id": "R-BTA-6786072", "name": "p-Y705-STAT3,p-Y641-STAT6 dissociate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6786072", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6786072" } ] }, { "id": "R-BTA-6786095", "name": "JAK1 phosphorylates STAT3,STAT6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6786095", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6786095" } ] }, { "id": "R-BTA-6786096", "name": "IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6786096", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6786096" } ] }, { "id": "R-BTA-6786110", "name": "JAK1 binds IL4R in IL13-bound IL13R type II", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6786110", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6786110" } ] }, { "id": "R-BTA-6786124", "name": "STAT3,STAT6 bind p-Y-IL4R", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6786124", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6786124" } ] }, { "id": "R-BTA-6788571", "name": "STAT1,STAT3,STAT6 bind IL13:IL13R type II", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6788571", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6788571" } ] }, { "id": "R-BTA-6788582", "name": "STAT1,STAT3,STAT6 phosphorylation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6788582", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6788582" } ] }, { "id": "R-BTA-6788628", "name": "p-Y-STATs dissociate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6788628", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6788628" } ] }, { "id": "R-BTA-6809140", "name": "IL35 binds IL-12RB2:IL6ST receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-6809140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809140" } ] }, { "id": "R-BTA-873918", "name": "Transphosphorylation of JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F6RY99-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-873918", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-873918" } ] }, { "id": "R-BTA-873919", "name": "Phosphorylation of JAK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-873919", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-873919" } ] }, { "id": "R-BTA-873921", "name": "Binding of STAT1 to p-IFNGR1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-873921", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-873921" } ] }, { "id": "R-BTA-873922", "name": "Phosphorylation of STAT1 by JAK kinases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-873922", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-873922" } ] }, { "id": "R-BTA-873924", "name": "Phosphorylation of IFNGR1 by JAK kinases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-873924", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-873924" } ] }, { "id": "R-BTA-873926", "name": "IFNG dimer binds IFNGR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-873926", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-873926" } ] }, { "id": "R-BTA-873927", "name": "Release of STAT1 dimer from active receptor unit", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-873927", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-873927" } ] }, { "id": "R-BTA-877269", "name": "SOCS-1 and SOCS-3 binds to p-JAK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-877269", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-877269" } ] }, { "id": "R-BTA-8854645", "name": "IL22:IL22RA1:JAK1 binds IL10RB:TYK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8854645", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854645" } ] }, { "id": "R-BTA-8950210", "name": "Interleukin-27 dissociates from Interleukin-27 receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8950210", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8950210" } ] }, { "id": "R-BTA-8950340", "name": "IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8950340", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8950340" } ] }, { "id": "R-BTA-8950405", "name": "JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8950405", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8950405" } ] }, { "id": "R-BTA-8950441", "name": "p-Y701-STAT1 and p-Y705-STAT3 dissociate from IL27:IL27 receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8950441", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8950441" } ] }, { "id": "R-BTA-8950448", "name": "STAT4 binds to IL12RB2 in Interleukin-12 receptor complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8950448", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8950448" } ] }, { "id": "R-BTA-8950453", "name": "JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8950453", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8950453" } ] }, { "id": "R-BTA-8950485", "name": "STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8950485", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8950485" } ] }, { "id": "R-BTA-8950518", "name": "STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8950518", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8950518" } ] }, { "id": "R-BTA-8950537", "name": "JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8950537", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8950537" } ] }, { "id": "R-BTA-8950757", "name": "IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8950757", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8950757" } ] }, { "id": "R-BTA-8952807", "name": "p-Y693-STAT4 dissociates after IL12:IL12R interaction", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8952807", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8952807" } ] }, { "id": "R-BTA-8963734", "name": "IL9 binds IL9R:JAK1 and IL2RG:JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8963734", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8963734" } ] }, { "id": "R-BTA-8982162", "name": "pY705-STAT3 dissociates from IL19:IL20RA:p-JAK1:IL20RB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8982162", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8982162" } ] }, { "id": "R-BTA-8982163", "name": "IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8982163", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8982163" } ] }, { "id": "R-BTA-8982165", "name": "IL19:IL20RA:pJAK1:IL20RB binds STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8982165", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8982165" } ] }, { "id": "R-BTA-8983003", "name": "IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983003", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983003" } ] }, { "id": "R-BTA-8983063", "name": "JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983063", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983063" } ] }, { "id": "R-BTA-8983298", "name": "IL15 binds IL2RB:JAK1 and IL2RG:JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983298", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983298" } ] }, { "id": "R-BTA-8983300", "name": "IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983300", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983300" } ] }, { "id": "R-BTA-8983335", "name": "IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endosome, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983335", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983335" } ] }, { "id": "R-BTA-8983371", "name": "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983371", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983371" } ] }, { "id": "R-BTA-8983374", "name": "p-Y-STAT3 and p-STAT5 dissociates from IL15:IL15RA:IL2RB:p-JAK1:IL2RG:p-JAK3:p-Y-STAT3:p-STAT5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983374", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983374" } ] }, { "id": "R-BTA-8983378", "name": "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983378", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983378" } ] }, { "id": "R-BTA-8983384", "name": "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983384", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983384" } ] }, { "id": "R-BTA-8983518", "name": "IL35 binds IL6ST:IL6ST receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983518", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983518" } ] }, { "id": "R-BTA-8983834", "name": "JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983834", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983834" } ] }, { "id": "R-BTA-8983835", "name": "JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983835", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983835" } ] }, { "id": "R-BTA-8983841", "name": "STAT1 associates with IL6ST:IL6ST", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983841", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983841" } ] }, { "id": "R-BTA-8983845", "name": "p-STAT1 dissociates from IL6ST:IL6ST", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983845", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983845" } ] }, { "id": "R-BTA-8983983", "name": "p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983983", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983983" } ] }, { "id": "R-BTA-8983996", "name": "STAT1 and STAT4 associate with IL12RB2:IL6ST receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8983996", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8983996" } ] }, { "id": "R-BTA-8984001", "name": "IL35 binds IL27RA:IL12RB2 receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8984001", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8984001" } ] }, { "id": "R-BTA-8984012", "name": "JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8984012", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8984012" } ] }, { "id": "R-BTA-8984014", "name": "JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8984014", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8984014" } ] }, { "id": "R-BTA-8984021", "name": "STAT1,STAT3 associate with IL27RA:IL12RB2 receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8984021", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8984021" } ] }, { "id": "R-BTA-8984023", "name": "p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8984023", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8984023" } ] }, { "id": "R-BTA-8985900", "name": "p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8985900", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8985900" } ] }, { "id": "R-BTA-8985914", "name": "IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8985914", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8985914" } ] }, { "id": "R-BTA-8985929", "name": "IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8985929", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8985929" } ] }, { "id": "R-BTA-8985973", "name": "IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8985973", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8985973" } ] }, { "id": "R-BTA-8985988", "name": "IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8985988", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8985988" } ] }, { "id": "R-BTA-8986446", "name": "IL26 binds IL20RA:JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8986446", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8986446" } ] }, { "id": "R-BTA-8986480", "name": "IL26:IL20RA:JAK1 binds IL10RB:TYK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8986480", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8986480" } ] }, { "id": "R-BTA-8986972", "name": "IL24 binds IL20RA:JAK1:IL20RB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8986972", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8986972" } ] }, { "id": "R-BTA-8986985", "name": "IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytoplasm, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8986985", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8986985" } ] }, { "id": "R-BTA-8986994", "name": "IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8986994", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8986994" } ] }, { "id": "R-BTA-8986995", "name": "IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8986995", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8986995" } ] }, { "id": "R-BTA-8987012", "name": "IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987012", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987012" } ] }, { "id": "R-BTA-8987014", "name": "IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "F1N339-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987014", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987014" } ] }, { "id": "R-BTA-8987015", "name": "IL20 binds IL20RA:JAK1:IL20RB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987015", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987015" } ] }, { "id": "R-BTA-8987033", "name": "p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987033", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987033" } ] }, { "id": "R-BTA-8987039", "name": "JAK1 binds IL20RA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987039", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987039" } ] }, { "id": "R-BTA-8987040", "name": "IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987040", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987040" } ] }, { "id": "R-BTA-8987042", "name": "IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987042", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987042" } ] }, { "id": "R-BTA-8987043", "name": "IL22RA1 binds JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987043", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987043" } ] }, { "id": "R-BTA-8987063", "name": "IL24:IL22RA1:p-JAK1:IL20RB binds STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987063", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987063" } ] }, { "id": "R-BTA-8987070", "name": "IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "F1N339-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987070", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987070" } ] }, { "id": "R-BTA-8987080", "name": "IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987080", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987080" } ] }, { "id": "R-BTA-8987084", "name": "IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987084", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987084" } ] }, { "id": "R-BTA-8987096", "name": "IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987096", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987096" } ] }, { "id": "R-BTA-8987097", "name": "IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987097", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987097" } ] }, { "id": "R-BTA-8987104", "name": "IL20:IL20RA:JAK1:IL20RB:pJAK2,pJAK3 binds STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987104", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987104" } ] }, { "id": "R-BTA-8987105", "name": "IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987105", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987105" } ] }, { "id": "R-BTA-8987120", "name": "JAK1 binds IFNLR1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987120", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987120" } ] }, { "id": "R-BTA-8987129", "name": "JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987129", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987129" } ] }, { "id": "R-BTA-8987132", "name": "IL22:pY251,pY301IL22RA1:pJAK1:PTPN11:IL10RB:pTYK2 binds PTPN11", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "F1N339-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987132", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987132" } ] }, { "id": "R-BTA-8987141", "name": "IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987141", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987141" } ] }, { "id": "R-BTA-8987150", "name": "IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987150", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987150" } ] }, { "id": "R-BTA-8987156", "name": "p-STAT3 dissociates from IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987156" } ] }, { "id": "R-BTA-8987161", "name": "p-STAT3 dissociates from IL24:IL22RA1:pJAK1:IL20RB:pSTAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987161", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987161" } ] }, { "id": "R-BTA-8987179", "name": "IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987179", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987179" } ] }, { "id": "R-BTA-8987202", "name": "IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987202", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987202" } ] }, { "id": "R-BTA-8987220", "name": "IL20:IL20RA:JAK1:IL20RB binds JAK2,JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987220", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987220" } ] }, { "id": "R-BTA-8987230", "name": "p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987230", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987230" } ] }, { "id": "R-BTA-8987236", "name": "p-Y705-STAT3 dissociates from IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "F1N339-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987236" } ] }, { "id": "R-BTA-8987255", "name": "IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987255", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987255" } ] }, { "id": "R-BTA-8987266", "name": "IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987266", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987266" } ] }, { "id": "R-BTA-8987270", "name": "p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-8987270", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8987270" } ] }, { "id": "R-BTA-9005980", "name": "IL21 binds IL21R:JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9005980", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9005980" } ] }, { "id": "R-BTA-9006844", "name": "IL21:IL21R:JAK1 binds IL2RG:JAK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9006844", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9006844" } ] }, { "id": "R-BTA-9006850", "name": "IL21 receptor JAK phosphorylation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9006850", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9006850" } ] }, { "id": "R-BTA-9006870", "name": "IL21 receptor STAT phosphorylation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9006870", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9006870" } ] }, { "id": "R-BTA-9006873", "name": "IL21 receptor STAT binding", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9006873", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9006873" } ] }, { "id": "R-BTA-9009227", "name": "IL20 binds to IL22RA1:JAK1:IL20RB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9009227", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9009227" } ] }, { "id": "R-BTA-9011748", "name": "IL9R binds JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9011748", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9011748" } ] }, { "id": "R-BTA-9025969", "name": "IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9025969", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9025969" } ] }, { "id": "R-BTA-909552", "name": "Phosphorylation of STAT1 at Ser727", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "Q3MHJ9-1", "Q2HJF7-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-909552", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-909552" } ] }, { "id": "R-BTA-909718", "name": "Formation of p-STAT1 homodimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-BTA-380745" ], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-909718", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-909718" } ] }, { "id": "R-BTA-909719", "name": "Recruitment of STAT2 to p-IFNAR1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-909719", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-909719" } ] }, { "id": "R-BTA-909720", "name": "IFN alpha/beta binds to IFNAR2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-909720", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-909720" } ] }, { "id": "R-BTA-909722", "name": "Release of p-STAT2:p-STAT1 dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-909722", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-909722" } ] }, { "id": "R-BTA-909724", "name": "Recruitment of IFNAR1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-909724", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-909724" } ] }, { "id": "R-BTA-909729", "name": "Activation of JAK kinases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-909729", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-909729" } ] }, { "id": "R-BTA-909730", "name": "Phosphorylation of INFAR1 by TYK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-909730", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-909730" } ] }, { "id": "R-BTA-909732", "name": "Phosphorylation of STAT2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-909732", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-909732" } ] }, { "id": "R-BTA-912527", "name": "SHC1 mediates cytokine-induced phosphorylation of GAB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-912527", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-912527" } ] }, { "id": "R-BTA-913374", "name": "Phosphorylated SHC1 recruits SHIP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "E1BBJ7-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-913374", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-913374" } ] }, { "id": "R-BTA-913424", "name": "The SHC1:SHIP1 complex is stabilized by GRB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "E1BEL4-1", "F6RY99-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-913424", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-913424" } ] }, { "id": "R-BTA-919404", "name": "Phosphorylated STAT5 is released", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEL4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-919404", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-919404" } ] }, { "id": "R-BTA-9674816", "name": "p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [ "R-BTA-9674821" ], "output_participant_list": [ "R-BTA-9647915" ], "enzyme_list": [ "A0AAA9SXH6-1", "A0A3Q1LMP2-1", "F1MCX4-1", "F1MWN2-1", "F1N339-1", "A0A3Q1MHG9-1", "A0ABI0P1V8-1", "F1N261-1" ], "evidence": [ { "id": "R-BTA-9674816", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9674816" } ] }, { "id": "R-BTA-9677579", "name": "CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1", "F1N261-1" ], "evidence": [ { "id": "R-BTA-9677579", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9677579" } ] }, { "id": "R-BTA-9677585", "name": "CSF3 dimer:CSFR:LYN:JAK1 binds CSFR:LYN:JAK1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1", "F1N261-1" ], "evidence": [ { "id": "R-BTA-9677585", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9677585" } ] }, { "id": "R-BTA-9678561", "name": "IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9678561", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9678561" } ] }, { "id": "R-BTA-9678935", "name": "IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9678935", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9678935" } ] }, { "id": "R-BTA-9696179", "name": "IFNAR2:JAK1:STAT2 binds type 1 interferon analogs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9696179", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9696179" } ] }, { "id": "R-BTA-9705738", "name": "SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "F1MWN2-1", "Q1RMX2-1", "Q2TA10-1", "A0A3Q1MHG9-1", "A0ABI0P1V8-1", "F1N261-1" ], "evidence": [ { "id": "R-BTA-9705738", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9705738" } ] }, { "id": "R-BTA-9707977", "name": "CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal membrane, endocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "F1MWN2-1", "A0A3Q1MHG9-1", "A0ABI0P1V8-1", "F1N261-1" ], "evidence": [ { "id": "R-BTA-9707977", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9707977" } ] }, { "id": "R-BTA-9732738", "name": "JAK1-mediated phosphorylation of RAF1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9732738", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9732738" } ] }, { "id": "R-BTA-9732753", "name": "JAK1-activated RAF1 phosphorylates MAPKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "P46196-1", "E1B8P9-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9732753", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9732753" } ] }, { "id": "R-BTA-9734547", "name": "JAK2-activated MAPKs phosphorylate YBX1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-BTA-9736840" ], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "P46196-1", "E1B8P9-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9734547", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9734547" } ] }, { "id": "R-BTA-9931290", "name": "IL6-activated JAK1 phosphorylates CD274", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [ "R-BTA-9931296" ], "enzyme_list": [ "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9931290", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9931290" } ] }, { "id": "R-BTA-9958871", "name": "Tyrosine phosphorylation of STAT3 by IL6 receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9958871", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958871" } ] }, { "id": "R-BTA-9958877", "name": "p-Y705-STAT3 dissociates from IL6 receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9958877", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958877" } ] }, { "id": "R-BTA-9958878", "name": "Tyrosine phosphorylated IL6ST binds STAT3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9SXH6-1", "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-9958878", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958878" } ] }, { "id": "R-BTA-997309", "name": "Dephosphorylation of STAT1 by SHP2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "F1N339-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-997309", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-997309" } ] }, { "id": "R-BTA-997311", "name": "Dephosphorylation of TYK2 by PTP1B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-997311", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-997311" } ] }, { "id": "R-BTA-997314", "name": "Dephosphorylation of JAK1 by SHP1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MCX4-1", "F6RY99-1", "A0ABI0P1V8-1" ], "evidence": [ { "id": "R-BTA-997314", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-997314" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-380745", "participant_name": "STAT1 [cytosol]", "crossref": [ { "id": "A0A3S5ZPJ6", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000007867", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000010351", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000010351", "database": "ENSEMBL", "url": "" }, { "id": "56151", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-9647915", "participant_name": "KRAS [plasma membrane]", "crossref": [ { "id": "ENSBTAG00000009778", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000043161", "database": "ENSEMBL", "url": "" }, { "id": "E1BMX0", "database": "UniProt", "url": "" }, { "id": "ENSBTAP00000040751", "database": "ENSEMBL", "url": "" }, { "id": "30710", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-9674821", "participant_name": "phospho-KRAS [plasma membrane]", "crossref": [ { "id": "E1BMX0", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000009778", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000040751", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000043161", "database": "ENSEMBL", "url": "" }, { "id": "30710", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-9736840", "participant_name": "YBX1 [cytosol]", "crossref": [ { "id": "P67808", "database": "UniProt", "url": "" }, { "id": "NP_777240.1", "database": "RefSeq", "url": "" }, { "id": "50233", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-9931296", "participant_name": "phospho-CD274 [endoplasmic reticulum membrane]", "crossref": [ { "id": "27019", "database": "VGNC", "url": "" }, { "id": "C5NU11", "database": "UniProt", "url": "" }, { "id": "NP_001156884.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LI98", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LI98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI98" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q1LI98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI98" } ] } ] }, { "uniprot_ac": "A0A3Q1LMP2", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LT44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT44" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1LT44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT44" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LUE0", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LUE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUE0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1LUE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUE0" } ] } ] }, { "uniprot_ac": "A0A3Q1LVP1", "gene_name": "PTK2B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LVP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVP1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q1LVP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVP1" } ] } ] }, { "uniprot_ac": "A0A3Q1M0U5", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] 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ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] } ] }, { "uniprot_ac": "A0A3Q1MEZ6", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MF99", "gene_name": "TXK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MF99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF99" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q1MF99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF99" } ] } ] }, { "uniprot_ac": "A0A3Q1MHB0", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHB0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHB0" } ] } ] }, { "uniprot_ac": "A0A3Q1MHG9", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHG9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q1MHG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHG9" } ] } ] }, { "uniprot_ac": "A0A3Q1MJG0", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MJG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJG0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1MJG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJG0" } ] } ] }, { "uniprot_ac": "A0A3Q1MKW9", "gene_name": "ALK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKW9", "database": "UniProtKB", "url": 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"id": "A0AAA9SA57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA57" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SA57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA57" } ] } ] }, { "uniprot_ac": "A0AAA9SBR4", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SBR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SBR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR4" } ] } ] }, { "uniprot_ac": "A0AAA9SN20", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SN20", "database": "UniProtKB", "url": 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"ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] } ] }, { "uniprot_ac": "A0AAA9SW95", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] } ] }, { "uniprot_ac": "A0AAA9SXH6", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { 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{ "uniprot_ac": "A0AAA9TMY2", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMY2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9TMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMY2" } ] } ] }, { "uniprot_ac": "A0AAA9TQL1", "gene_name": "DDR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] } ] }, { "uniprot_ac": "A0AAA9TRY4", "gene_name": "CSF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] } ] }, { "uniprot_ac": "A0AAF6DMB3", "gene_name": "DDR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NX25", "gene_name": "RIGI", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0NX25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0NX25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX25" } ] } ] }, { "uniprot_ac": "A0ABI0P1V8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] } ] }, { "uniprot_ac": "A0JNB0", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0JNB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JNB0" } ] } ] }, { "uniprot_ac": "A2VEA3", "gene_name": "ARIH1", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A2VEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VEA3" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A2VEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VEA3" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PJC4", "gene_name": "UBE2L6", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] } ] }, { "uniprot_ac": "E1B6X6", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B6X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1B6X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B6X6" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B9H4", "gene_name": "PKDCC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BBJ7", "gene_name": "INPPL1", "activity": [ { "ec_number": "3.1.3.86", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate.", "evidence": [ { "id": "E1BBJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBJ7" } ] }, { "ec_number": "3.1.3.86", "activity": "", "evidence": [ { "id": "E1BBJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBJ7" } ] } ] }, { "uniprot_ac": "E1BCZ6", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] } ] }, { "uniprot_ac": "E1BE66", "gene_name": "PIK3CD", "activity": [ { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1BE66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE66" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1BE66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE66" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1BE66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE66" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1BE66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BE66" } ] } ] }, { "uniprot_ac": "E1BEL4", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEL4" } ] } ] }, { "uniprot_ac": "E1BER5", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BER5" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BIM8", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] } ] }, { "uniprot_ac": "E1BJ31", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] } ] }, { "uniprot_ac": "E1BJS9", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] } ] }, { "uniprot_ac": "E1BKP7", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] } ] }, { "uniprot_ac": "E1BMP9", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] } ] }, { "uniprot_ac": "E1BNA8", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] } ] }, { "uniprot_ac": "E1BNE0", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] } ] }, { "uniprot_ac": "E1BPA0", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPI3", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "F1MC14", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] } ] }, { "uniprot_ac": "F1MC23", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] } ] }, { "uniprot_ac": "F1MCX4", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] } ] }, { "uniprot_ac": "F1MFH7", "gene_name": "EPHA1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] } ] }, { "uniprot_ac": "F1MII5", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] } ] }, { "uniprot_ac": "F1MKR1", "gene_name": "EPHA8", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] } ] }, { "uniprot_ac": "F1ML02", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] } ] }, { "uniprot_ac": "F1MN51", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] } ] }, { "uniprot_ac": "F1MNW2", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] } ] }, { "uniprot_ac": "F1MQH2", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] } ] }, { "uniprot_ac": "F1MRU0", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] } ] }, { "uniprot_ac": "F1MS00", "gene_name": "RET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] } ] }, { "uniprot_ac": "F1MS29", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] } ] }, { "uniprot_ac": "F1MWN2", "gene_name": "HCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] } ] }, { "uniprot_ac": "F1MX49", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1N0D3", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] } ] }, { "uniprot_ac": "F1N1Q0", "gene_name": "SRMS", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] } ] }, { "uniprot_ac": "F1N261", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] } ] }, { "uniprot_ac": "F1N339", "gene_name": "PTPN11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N339" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N339" } ] } ] }, { "uniprot_ac": "F1N381", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] } ] }, { "uniprot_ac": "F1N3R6", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6H6", "gene_name": "EPHA10", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6H6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6H6" } ] } ] }, { "uniprot_ac": "F1N6J0", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6J0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N6J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6J0" } ] } ] }, { "uniprot_ac": "F1N758", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] } ] }, { "uniprot_ac": "F1N759", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] } ] }, { "uniprot_ac": "F1N780", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N780" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N780" } ] } ] }, { "uniprot_ac": "F1N781", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N781" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N781" } ] } ] }, { "uniprot_ac": "F6QXU6", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QXU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6QXU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QXU6" } ] } ] }, { "uniprot_ac": "F6RY99", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F6RY99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F6RY99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RY99" } ] } ] }, { "uniprot_ac": "F6S1J8", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6S1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1J8" } ] } ] }, { "uniprot_ac": "G1K218", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G1K218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "G1K218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ] } ] }, { "uniprot_ac": "G3X680", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3X680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X680" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "G3X680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X680" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P43481", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P43481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43481" } ] } ] }, { "uniprot_ac": 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The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. 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"expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0E9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000018449", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018449", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22298", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22298", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR048724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048726", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048726", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EAFRQCQ", "url": "https://omabrowser.org/oma/group/EAFRQCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N7I5", "url": "https://www.orthodb.org/?gene=F1N7I5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18902", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18902", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18902:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18902:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-68875", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-68875", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0NN75", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NN75-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0E9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0E9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1K6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1K6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1K6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7I5", "url": "https://www.uniprot.org/uniprotkb/F1N7I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7I5-1", "url": "https://www.uniprot.org/uniprotkb/F1N7I5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLHATRAAALLTWVNSLRLADPVEAVLQLQDCGVFIRIIDGILGTDEGQQILQRPVPERLEFVCSFLQKNRKHPSSAECLVSVQKVMEGSELELAKVAMLLLYHSSMSSRSLRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLESFLQKAPVPSPRSSTISEELSPPSHQAKREVHFLELQKVASSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERNNRDELELELAENRKLLTEKDAQIAMMQQRIDRLTQLNEKQAASPLEPRELEELRGKNESLTVRLHETLKQCQDLKTEKSQMDRRINQLSEENGDLSFKLREFASHLQQLQGALNELTEEHSRATQEWMQKQAHLDKELGTALQDKKCLEEKNEILQGKLSQLEEHLAQLRENPPQEKGEVLGDVLQLETLKQEAATLAADNTQLQARVAALETERGQREAKLLAERSHFEGEKQQLAGLIAELQGSLSNLSQAKEELEQASQAQVARLSTQVATLTSELDTLNTAVQQRDGELAGLKQQAQTEQAQLTQTLRQQEEAAQGLRQQVEQLSSSLERKERQLEEAATEKEATRRDQAQQLAAAAEEREAALRERDTALQQLGAVEKEKAAELDVLQEQLRAAHEAQDGAQSSLTQAQQEKAELSQKVEELHTHVEAARQEQSEVQAQVAELKAQLRSEQQKTTEWERVAQEKAQLQEQVRALEESLKATTGNLEKEKRRAADTLAEQQRCICRLEAETQSLVEQHEQGQKELEEERAGRKGLEARLQQLGEAHQAQTEALRQELAEAVASQREAENECEQLAKEVATWRERYEDSQQEEEQYGAMFQEQLMTLKEECEKARQELQEAKEKVVGIEAHSELQISRQQDELAQLHASLARALQQVQEKEGRAQQLATDLATLQEKMAATSKEVARLEALVRKAGGQPETASPELFKEPPRAGDRESEWLEEQQGRPFCSTQAALQAMEREAEQMGSELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQNALNEQRVEFAALQEALAQALREKEGMDQELAKLHGQEAAQGAVLKELQQTVERLKEQLAKKEEGHACGLRTQSEATEKTEPEGSELQALQAEVSRLEQQAREHQEKASSLEQSLESERAAHAEQASTLKTLQGQLEQKAQELGSSQDALASTQRELATLRAKAQEHSKAEDEWKAQVARGQQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQAETASSSARAAERSSALREEVQTLREEAEKQRVASESLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALASELLPVKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELLPLRQKVAEQERMAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERASLGRQFLEVELDQAREKYSQELAAVRADAETRLAEMQREVQSTARELEVMTAKYEGAKAKVLEERQRFQEERQKLTAQVEQLELFQREQTKQVEELSKKLADHEQASKAQQQKLKVQAQGGESQQEVQRLQAQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRGLEQLQTENKELRAEVDRLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKSQLDLSIDSLDLSCEEGTPLSVTSKLPRTQPDGTSIPGEPASPISQRLPPKVESLESLYFTPIPARGQAPLESSLDSLGDISLDSSRKTRSARRRTTQIINITMTKKLDVEDPDSANASFYSTQSAPTSQAGLRAASSTQSLARLGSPDDGNSTLFSLPGYRPTTRSSARRSQAGMSSGAPPGRNSFYVGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLPAITDEEIKTGDPRETLRRASMQPTQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATTCFPRPMTPRDRHEGRRHSSTEAQKKAVPAVKQADRRQSMAFSILNTPKKLGNSLLRKAASKKAPSKASPNPRSGTRRSPRIATTAASAATAAASAAATTPRAKGKAKH", "length": 2114, "header": "tr|A0ABI0P0E9-1|A0ABI0P0E9_BOVIN Isoform 1 of Nuclear mitotic apparatus protein 1 OS=Bos taurus OX=9913 GN= PE=1 SV=1 CANONICAL=A0ABI0P0E9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NN75-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9/entry#A0ABI0NN75-1", "sequence": { "sequence": "MTLHATRAAALLTWVNSLRLADPVEAVLQLQDCGVFIRIIDGILGTDEGQQILQRPVPERLEFVCSFLQKNRKHPSSAECLVSVQKVMEGSELELAKVAMLLLYHSSMSSRSLRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLESFLQKAPVPSPRSSTISEELSPPSHQAKREVHFLELQKVASSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERNNRDELELELAENRKLLTEKDAQIAMMQQRIDRLTQLNEKQAASPLEPRELEELRGKNESLTVRLHETLKQCQDLKTEKSQMDRRINQLSEENGDLSFKLREFASHLQQLQGALNELTEEHSRATQEWMQKQAHLDKELGTALQDKKCLEEKNEILQGKLSQLEEHLAQLRENPPQEKGEVLGDVLQVEELSKKLADHEQASKAQQQKLKVQAQGGESQQEVQRLQAQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRGLEQLQTENKELRAEVDRLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKSQLDLSIDSLDLSCEEGTPLSVTSKLPRTQPDGTSIPGEPASPISQRLPPKVESLESLYFTPIPARGQAPLESSLDSLGDISLDSSRKTRSARRRTTQIINITMTKKLDVEDPDSANASFYSTQSAPTSQAGLRAASSTQSLARLGSPDDGNSTLFSLPGYRPTTRSSARRSQAGMSSGAPPGRNSFYVGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLPAITDEEIKTGDPRETLRRASMQPTQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATTCFPRPMTPRDRHEGRRHSSTEAQKKAVPAVKQADRRQSMAFSILNTPKKLGNSLLRKAASKKAPSKASPNPRSGTRRSPRIATTAASAATAAASAAATTPRAKGKAKH", "length": 978, "header": "tr|A0ABI0NN75-1|A0ABI0P0E9_BOVIN Computationally mapped isoform of Nuclear mitotic apparatus protein 1 OS=Bos taurus OX=9913 GN= PE=1 SV=1 CANONICAL=A0ABI0P0E9-1" }, "locus": { "chromosome": "15", "start_pos": 51673834, "end_pos": 51643268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137247.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137247.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107179.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107179.1" } ] } }, { "isoform_ac": "A0ABI0P0E9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9/entry#A0ABI0P0E9-1", "sequence": { "sequence": "MTLHATRAAALLTWVNSLRLADPVEAVLQLQDCGVFIRIIDGILGTDEGQQILQRPVPERLEFVCSFLQKNRKHPSSAECLVSVQKVMEGSELELAKVAMLLLYHSSMSSRSLRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLESFLQKAPVPSPRSSTISEELSPPSHQAKREVHFLELQKVASSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERNNRDELELELAENRKLLTEKDAQIAMMQQRIDRLTQLNEKQAASPLEPRELEELRGKNESLTVRLHETLKQCQDLKTEKSQMDRRINQLSEENGDLSFKLREFASHLQQLQGALNELTEEHSRATQEWMQKQAHLDKELGTALQDKKCLEEKNEILQGKLSQLEEHLAQLRENPPQEKGEVLGDVLQLETLKQEAATLAADNTQLQARVAALETERGQREAKLLAERSHFEGEKQQLAGLIAELQGSLSNLSQAKEELEQASQAQVARLSTQVATLTSELDTLNTAVQQRDGELAGLKQQAQTEQAQLTQTLRQQEEAAQGLRQQVEQLSSSLERKERQLEEAATEKEATRRDQAQQLAAAAEEREAALRERDTALQQLGAVEKEKAAELDVLQEQLRAAHEAQDGAQSSLTQAQQEKAELSQKVEELHTHVEAARQEQSEVQAQVAELKAQLRSEQQKTTEWERVAQEKAQLQEQVRALEESLKATTGNLEKEKRRAADTLAEQQRCICRLEAETQSLVEQHEQGQKELEEERAGRKGLEARLQQLGEAHQAQTEALRQELAEAVASQREAENECEQLAKEVATWRERYEDSQQEEEQYGAMFQEQLMTLKEECEKARQELQEAKEKVVGIEAHSELQISRQQDELAQLHASLARALQQVQEKEGRAQQLATDLATLQEKMAATSKEVARLEALVRKAGGQPETASPELFKEPPRAGDRESEWLEEQQGRPFCSTQAALQAMEREAEQMGSELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQNALNEQRVEFAALQEALAQALREKEGMDQELAKLHGQEAAQGAVLKELQQTVERLKEQLAKKEEGHACGLRTQSEATEKTEPEGSELQALQAEVSRLEQQAREHQEKASSLEQSLESERAAHAEQASTLKTLQGQLEQKAQELGSSQDALASTQRELATLRAKAQEHSKAEDEWKAQVARGQQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQAETASSSARAAERSSALREEVQTLREEAEKQRVASESLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALASELLPVKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELLPLRQKVAEQERMAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERASLGRQFLEVELDQAREKYSQELAAVRADAETRLAEMQREVQSTARELEVMTAKYEGAKAKVLEERQRFQEERQKLTAQVEQLELFQREQTKQVEELSKKLADHEQASKAQQQKLKVQAQGGESQQEVQRLQAQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRGLEQLQTENKELRAEVDRLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKSQLDLSIDSLDLSCEEGTPLSVTSKLPRTQPDGTSIPGEPASPISQRLPPKVESLESLYFTPIPARGQAPLESSLDSLGDISLDSSRKTRSARRRTTQIINITMTKKLDVEDPDSANASFYSTQSAPTSQAGLRAASSTQSLARLGSPDDGNSTLFSLPGYRPTTRSSARRSQAGMSSGAPPGRNSFYVGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLPAITDEEIKTGDPRETLRRASMQPTQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATTCFPRPMTPRDRHEGRRHSSTEAQKKAVPAVKQADRRQSMAFSILNTPKKLGNSLLRKAASKKAPSKASPNPRSGTRRSPRIATTAASAATAAASAAATTPRAKGKAKH", "length": 2114, "header": "tr|A0ABI0P0E9-1|A0ABI0P0E9_BOVIN Isoform 1 of Nuclear mitotic apparatus protein 1 OS=Bos taurus OX=9913 GN= PE=1 SV=1 CANONICAL=A0ABI0P0E9-1" }, "locus": { "chromosome": "15", "start_pos": 51673834, "end_pos": 51643268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147434.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147434.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107209.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107209.1" } ] } }, { "isoform_ac": "A0ABI0P1K6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9/entry#A0ABI0P1K6-1", "sequence": { "sequence": "MTLHATRAAALLTWVNSLRLADPVEAVLQLQDCGVFIRIIDGILGTDEGQQILQRPVPERLEFVCSFLQKNRKHPSSAECLVSVQKVMEGSELELAKVAMLLLYHSSMSSRSLRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLESFLQKAPVPSPRSSTISEELSPPSHQAKREVHFLELQKVASSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERNNRDELELELAENRKLLTEKDAQIAMMQQRIDRLTQLNEKQAASPLEPRELEELRGKNESLTVRLHETLKQCQDLKTEKSQMDRRINQLSEENGDLSFKLREFASHLQQLQGALNELTEEHSRATQEWMQKQAHLDKELGTALQDKKCLEEKNEILQGKLSQLEEHLAQLRENPPQEKGEVLGDVLQLETLKQEAATLAADNTQLQARVAALETERGQREAKLLAERSHFEGEKQQLAGLIAELQGSLSNLSQAKEELEQASQAQVARLSTQVATLTSELDTLNTAVQQRDGELAGLKQQAQTEQAQLTQTLRQQEEAAQGLRQQVEQLSSSLERKERQLEEAATEKEATRRDQAQQLAAAAEEREAALRERDTALQQLGAVEKEKAAELDVLQEQLRAAHEAQDGAQSSLTQAQQEKAELSQKVEELHTHVEAARQEQSEVQAQVAELKAQLRSEQQKTTEWERVAQEKAQLQEQVRALEESLKATTGNLEKEKRRAADTLAEQQRCICRLEAETQSLVEQHEQGQKELEEERAGRKGLEARLQQLGEAHQAQTEALRQELAEAVASQREAENECEQLAKEVATWRERYEDSQQEEEQYGAMFQEQLMTLKEECEKARQELQEAKEKVVGIEAHSELQISRQQDELAQLHASLARALQQVQEKEGRAQQLATDLATLQEKMAATSKEVARLEALVRKAGGQPETASPELFKEPPRAGDRESEWLEEQQGRPFCSTQAALQAMEREAEQMGSELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQNALNEQRVEFAALQEALAQALREKEGMDQELAKLHGQEAAQGAVLKELQQTVERLKEQLAKKEEGHACGLRTQSEATEKTEPEGSELQALQAEVSRLEQQAREHQEKASSLEQSLESERAAHAEQASTLKTLQGQLEQKAQELGSSQDALASTQRELATLRAKAQEHSKAEDEWKAQVARGQQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQAETASSSARAAERSSALREEVQTLREEAEKQRVASESLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALASELLPVKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELLPLRQKVAEQERMAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERASLGRQFLEVELDQAREKYSQELAAVRADAETRLAEMQREVQSTARELEVMTAKYEGAKAKVLEERQRFQEERQKLTAQVEELSKKLADHEQASKAQQQKLKVQAQGGESQQEVQRLQAQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRGLEQLQTENKELRAEVDRLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKSQLDLSIDSLDLSCEEGTPLSVTSKLPRTQPDGTSIPGEPASPISQRLPPKVESLESLYFTPIPARGQAPLESSLDSLGDISLDSSRKTRSARRRTTQIINITMTKKLDVEDPDSANASFYSTQSAPTSQAGLRAASSTQSLARLGSPDDGNSTLFSLPGYRPTTRSSARRSQAGMSSGAPPGRNSFYVGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLPAITDEEIKTGDPRETLRRASMQPTQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATTCFPRPMTPRDRHEGRRHSSTEAQKKAVPAVKQADRRQSMAFSILNTPKKLGNSLLRKAASKKAPSKASPNPRSGTRRSPRIATTAASAATAAASAAATTPRAKGKAKH", "length": 2100, "header": "tr|A0ABI0P1K6-1|A0ABI0P1K6_BOVIN Computationally mapped isoform of Nuclear mitotic apparatus protein 1 OS=Bos taurus OX=9913 GN= PE=1 SV=1 CANONICAL=A0ABI0P0E9-1" }, "locus": { "chromosome": "15", "start_pos": 51673834, "end_pos": 51643268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140824.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140824.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104866.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104866.1" } ] } }, { "isoform_ac": "F1N7I5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9/entry#F1N7I5-1", "sequence": { "sequence": "MSGFTKMTLHATRAAALLTWVNSLRLADPVEAVLQLQDCGVFIRIIDGILGTDEGQQILQRPVPERLEFVCSFLQKNRKHPSSAECLVSVQKVMEGSELELAKVAMLLLYHSSMSSRSLRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLESFLQKAPVPSPRSSTISEELSPPSHQAKREVHFLELQKVASSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERNNRDELELELAENRKLLTEKDAQIAMMQQRIDRLTQLNEKQAASPLEPRELEELRGKNESLTVRLHETLKQCQDLKTEKSQMDRRINQLSEENGDLSFKLREFASHLQQLQGALNELTEEHSRATQEWMQKQAHLDKELGTALQDKKCLEEKNEILQGKLSQLEEHLAQLRENPPQEKGEVLGDVLQLETLKQEAATLAADNTQLQARVAALETERGQREAKLLAERSHFEGEKQQLAGLIAELQGSLSNLSQAKEELEQASQAQVARLSTQVATLTSELDTLNTAVQQRDGELAGLKQQAQTEQAQLTQTLRQQEEAAQGLRQQVEQLSSSLERKERQLEEAATEKEATRRDQAQQLAAAAEEREAALRERDTALQQLGAVEKEKAAELDVLQEQLRAAHEAQDGAQSSLTQAQQEKAELSQKVEELHTHVEAARQEQSEVQAQVAELKAQLRSEQQKTTEWERVAQEKAQLQEQVRALEESLKATTGNLEKEKRRAADTLAEQQRCICRLEAETQSLVEQHEQGQKELEEERAGRKGLEARLQQLGEAHQAQTEALRQELAEAVASQREAENECEQLAKEVATWRERYEDSQQEEEQYGAMFQEQLMTLKEECEKARQELQEAKEKVVGIEAHSELQISRQQDEALQQVQEKEGRAQQLATDLATLQEKMAATSKEVARLEALVRKAGGQPETASPELFKEPPRAGDRESEWLEEQQGRPFCSTQAALQAMEREAEQMGSELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAAKAELEMRLQNALNEQRVEFAALQEALAQALREKEGMDQELAKLHGQEAAQGAVLKELQQTVERLKEQLAKKEEGRPQSLGTASREDACGLRTQSEATEKTEPEGSELQALQAEVSRLEQQAREHQEKASSLEQSLESERAAHAEQASTLKTLQGQLEQKAQELGSSQDALASTQRELATLRAKAQEHSKAEDEWKAQVARGQQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQAETASSSARAAERSSALREEVQTLREEAEKQRVASESLRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALASELLPVKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELLPLRQKVAEQERMAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERASLGRQFLEVELDQAREKYSQELAAVRADAETRLAEMQREVQSTARELEVMTAKYEGAKAKVLEERQRFQEERQKLTAQVSLSPLASLPQVEELSKKLADHEQASKAQQQKLKAQGGESQQEVQRLQAQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRGLEQLQTENKELRAEVDRLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKSQLDLSIDSLDLSCEEGTPLSVTSKLPRTQPDGTSIPGEPASPISQRLPPKVESLESLYFTPIPARGQAPLESSLDSLGDISLDSSRKTRSARRRTTQIINITMTKKLDVEDPDSANASFYSTQSAPTSQAGLRAASSTQSLARLGSPDDGNSTLFSLPGYRPTTRSSARRSQAGMSSGAPPGREPFAIGRLQMPGQSTDHFFYPTQPSLSLPAITDEEIKTGDPRETLRRASMQPTQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATTCFPRPMTPRDRHEGRRHSSTEAQKKAVPAVKQADRRQSMAFSILNTPKKLGNSLLRKAASKKAPSKASPNPRSGTRRSPRIATTAASAATAAASAAATTPRAKGK", "length": 2092, "header": "tr|F1N7I5-1|A0ABI0P0E9_BOVIN Computationally mapped isoform of Nuclear mitotic apparatus protein 1 OS=Bos taurus OX=9913 GN= PE=1 SV=4 CANONICAL=A0ABI0P0E9-1" }, "locus": { "chromosome": "15", "start_pos": 51673852, "end_pos": 51643597, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024553.8", "url": "https://www.ensembl.org/id/ENSBTAT00000024553.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024553.7", "url": "https://www.ensembl.org/id/ENSBTAP00000024553.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-BTA-68875", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-68875", "resource": "Reactome", "description": "Mitotic Prophase" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IH76-1", "protein_name": "Nuclear mitotic apparatus protein 1", "gene_name": "numa1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKFNKNKAGPLLTWMNSVFPENQIWEFGHMRDGFRLLEICFKLKGREDVEAYKTLSLYNKLEIIFNDLHDDFHLTDRQRFLILGKISEGLDLELQLAKVALLLCYCSFKKTNPVALNSRTESDITFMFRFVRDDASGLCLDEGLDQFLDQDSVMNLANSSSGSSCSSPFYIDEESPMFGRFQRPPRVQFQELCTVASSSDSSPMQDLMSTPHFQLKKLRKELAHEGDVRDELEKELADHISIISEKEGLISQLQHRVERMLREQGELEKDHKAALLELQEKNESLLHRVHEVLKQCQDLKTDNSQKEKKIDELTEENGTLSAQLRNVFSQLARAEQEVAKLTVVHESAQTEWKNRKELLEKELNEAVTHKECLSEQVLILQGKISVLEDELKKAQSQERGEVLGPIMEWEKLKQELADLTLQLAQLQESISHLEKKKAEVEALLAEERCSFEKETARLQLVVFDLEKSINSIRLERETLQEALKTQKEMLSAQISALERDVSRLQQVEVQLTAEIKISADLRQQREELEGKVASLDRMVHSLHAEIQGLEVERASQQDAINSLISDLQIARATVQEYEKKLEEHQKVVAENNSLKNEACTMQQELNNHLKAIGDLQAEVNELRFEKTEEENKVSEALVKIESLQTEILHLCEKISLKDEEIRNLTKEYESVDNELKLVKEQNVEINAMIKSNRKEHEETVEKLQQELHCAASAASEKQEQMLVLSAEVTSLKEQICRYSENEAQKQQELSILEAQHNVLKENLTSLQNQLAEATTSASQKESEFILLQQELSHQETLREQTQELEKIKREELEGIVSELQAKIIEVSSIASEREACVSSLQYEMKDQLSKAKQCEADLRNEMKEKVGNLQELLDAANHGIAEKEHHLESLNQSLKQMELLYCQKEEEIIASQQAKQQLENNIAEQKQQLDEIQQNREILRNERDHLSTRVSSLQEEIHRSQQDFSDLQTDHNVLKEKLVNLQDQVEQAMITASQKESELLLLQQELSHQETLREKALELEAIKREEFEKKVKELQDRILEVSTLASQREAQVISLENEMRDQQLSANQSKDNLCREWQEKLGILKGELDVVSRDAADKDHQLESLDQKLKEMEMVVLQKEKDVMETHQAKEDLEKRIAELEECKQKLEIMRNERDHLSTEVASLKEEIHSYQDTQMQKQQTISVLEVENNALKENMAALEKQLAEEITTASQKNSELQNKLHQQESLHEKAQELEIGRHEEFERRVRELQAKVQEVSTLASEKEAVAYSLQEELTGHLKAKVSEDDLRRVLEEKVETLQREIETASCDATSKDGLLQTLDQKLRQMEMLCQQKEDAVFEIQNSKEDLQKEMNELVSKNQELEGCLQHLEMVKKEKDLLSNEVTSLKEQINDQSLRAKQSEADLCIVFEEKIETLQGQLESSSCDVSDKEKHLQTLHQKVSQMDLLCQQKENAVLEMQNAKEDLQKKIDELVSEKQQLEGCLQNLEMVKSERDLLSTEVTSLKDQLNDQDLKAKQSEDDLRKVLEEKIKNLQGQLETASRDVSEKDQLLQTLDQKVTQMDQLCKQKEKYALDLLQVKENLEKRIGEITVEKQQLEGCQQNLETVSKDKDNLLNELTFLKVEIQSYQEKEVQMKHELSVLENEHNILQENLDTLQKQVVELTASASQKESELQNEVCKQEKLQEKAQKLEKDAGDLQAKILEISTLASEREAQISSLKDEINSQHLKAKQSEDDLLRVFEEKIENLQGQLEIARLDVSDKDQLLQTLNQKLKQMEELCKQKETCVLEMHQTKEDLEKKTVELQADKSQQNQQNLEMLRQEKDHLKSLNQTIRRECEASRKIRAELELNVEEQTASILALKKASQQWEEQNQELLEQLKAKTEAVEHYKAQVEKAMNHYNGKKQLLLEAQELNKTLEQSLEVSKREAKALETELTLARMELNQANDKEKSLAAKVKTLEAQVDFADRQLREKRRIADDGEDLRQKENLYFRVPEKQQDTSADSLEFELNDSLNTTCRSAVPGESSTPLVRSSERLAAKRRALGAESLETLYFTPMGKQGYKRKVDHNDGFERKLESSITSIGDLVVDSAKKLTASARRRRTTQVINITLAKKAQGSSESEESFSSLHSARSHPNLAVHQSRPISIDFSEDGPATTLSKADTLQNLPGYRRSTVHSVGPPRATSTFCIGAENEPEHAADDWMRIAELQSRNKACLPHLKSSYPLESRPSLGPSFTVTDEDLRLGDPSETIRRASMMPGQILESLNSRRFSLAPETSSSQAPARSHPQRATMLPCQIQSSTAAHRASQLTKTSSRSHTSENKRSPLAPKRPASQLQGPDTPEAKKLASCFPRPMTPKGRFGNSQNRPPVSPAERRQSVMFTVVNTPKNSARGDSRLQRGLNKLRNSTRKSPAVASRALRSAVSGKSPLDVTLRKSPRNKSPKTSNAKKIKLRIKV", "length": 2450 }, "evidence": [ { "id": "A0ABI0P0E9", "url": "https://omabrowser.org/oma/group/A0ABI0P0E9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q7G0-1", "protein_name": "Nuclear mitotic apparatus protein 1", "gene_name": "Numa1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLHATRAATLLSWVNSLHVADPVETVLQLQDCSIFIKIINTIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQKVIEGSEMELAKMIMLFLYQSTMSSRNLRDWEQFEYGVQAELAVILKFMLDHEESLNLTEDLESFLEKVPYTHASTLSEELSPPSHQTKRKIRFLEIQRIASSSSENNFLSGSPSSPMGDILQTPQFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMTGLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAREASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEESLKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLMEQREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVESRQKRFEARQQEEARYGAMFQEQLMALKGEKTGQEVQEEAVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGRPFSSTHAAVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERSSALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLTEHDQASKVQQQKLKAFQAQRGESQQEVQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQVKPQLDLSIDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPTPARGQAPLETSLDSLGDAFPDSGRKTRSARRRTTQIINITMTKKLELEEPDSANSSFYSTQSAPASQANLRATSSTQSLARLGSPDDGNSALLSLPGYRPTTRSSARRSQARMSSGAPQGRNSFYMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPTLSLATITDEEMKTGDPRETLRRASMQPAQIAEGVGITTRQQRKRVSSETHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSSTADTQKKAAPVLKQADRRQSMAFSILNTPKKLGNSLLRRGASKKTPAKVSPNPRSGTRRSPRIATTTTGTATVATTPRAKGKVKH", "length": 2094 }, "evidence": [ { "id": "A0ABI0P0E9", "url": "https://omabrowser.org/oma/group/A0ABI0P0E9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LW91-1", "protein_name": "Nuclear mitotic apparatus protein 1", "gene_name": "Numa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLHATRASTLLSWVNSLHVADPVETVLQLQDCSIFIKIINSIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQKVMEGSEMELAKMVMLFLYHSTMSSRNPRDWEQFEYGVQAELAVILKFMLDHEDSPNLTEDLENFLEKVPSTYPSTLSEELSPPSHQAKRKIRFLEIQRIASSSSENNFLSGSPSSPVGDILQTPQFQMRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASPQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEQLEVFHREQTKQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQVKPQLDLSIDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARGQAPLETSLDSLGDAFPDSGRKTRSARRRTTQIINITMTKKLELEEPDSANSSFYSTQSAPASQANLRATSSTQSLARLGSPDDSNSALLSLPGYRPTTRSSARRSQTRTSSGAPHGRNSFYMGTCQDEPEQVDDWNRIAELQQRNRVCPPHLKTCYPLESRPALSLATITDEEMKTGDPRETLRRASMQPAQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATSCFPRPMTPRDRHEGRKQNSTADAQKKAAPVLKQSDRRQSMAFSILNTPKKLGNSLLRRGTSKKTPAKVSPNPRSGTRRSPRIATTTAGAATAATTPRAKGKAKH", "length": 2106 }, "evidence": [ { "id": "A0ABI0P0E9", "url": "https://omabrowser.org/oma/group/A0ABI0P0E9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14980-1", "protein_name": "Nuclear mitotic apparatus protein 1", "gene_name": "NUMA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSERLDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIRFLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAPASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRSGTRRSPRIATTTASAATAAAIGATPRAKGKAKH", "length": 2115 }, "evidence": [ { "id": "A0ABI0P0E9", "url": "https://omabrowser.org/oma/group/A0ABI0P0E9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of protein localization to spindle pole body", "id": "GO:1902365", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902365", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0E9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0E9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0E9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0E9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0E9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9" } ], "pmid": "" }, { "name": "mitotic spindle pole", "id": "GO:0097431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097431", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0E9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule minus-end binding", "id": "GO:0051011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051011", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0E9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1814, "end_pos": 1816, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1830, "end_pos": 1832, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1865, "end_pos": 1867, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P0E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0E9" }, { "id": "PF21670", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21670" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nuclear mitotic apparatus protein 1 N-terminal hook", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 153, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1814, "end_pos": 1816 }, { "start_pos": 1830, "end_pos": 1832 }, { "start_pos": 1865, "end_pos": 1867 }, { "start_pos": 284, "end_pos": 286 }, { "start_pos": 476, "end_pos": 478 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P529-1", "uniprot_ac": "A0ABI0P529", "uniprot_id": "A0ABI0P529_BOVIN", "mass": { "chemical_mass": 123153.0, "monoisotopic_mass": 123153.0 }, "refseq": { "ac": "XP_005218496", "name": "adenylate cyclase type 7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218496" }, "gene_names": [ { "name": "ADCY7", "type": "recommended", "evidence": [ { "id": "A0ABI0P529", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529" } ] }, { "name": "ADCY7", "type": "synonym", "evidence": [ { "id": "XP_005218496", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218496" } ] } ], "protein_names": [ { "name": "Adenylate cyclase type 7", "type": "recommended", "evidence": [ { "id": "A0ABI0P529", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529/entry#names_and_taxonomy" } ] }, { "name": "4.6.1.1", "type": "synonym", "evidence": [ { "id": "A0ABI0P529", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529/entry#names_and_taxonomy" } ] }, { "name": "adenylate cyclase type 7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005218496", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218496" } ] } ], "function": [ { "annotation": "Adenylate cyclase that mediates formation of both cyclic AMP (cAMP) and cyclic di-AMP (c-di-AMP). Acts as a key mediator of G protein-coupled receptor signaling by catalyzing the formation of cAMP downstream of G protein-coupled receptors. Functions in G protein-coupled receptor signaling cascades activated by thrombin, sphingosine 1-phosphate, dopamine and anaphylatoxin C5a. Mediates regulation of cAMP synthesis through synergistic action of the G alpha protein G(s) (GNAS) with G(13) (GNA13). Also involved in inflammation by acting as a diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into c-di-AMP. Following activation by TLR9, mediates formation of c-di-AMP, which directly activates NLRP3, thereby promoting assembly and maturation of the NLRP3 inflammasome. It is also required for the optimal functions of B- and T cells during adaptive immune responses by regulating cAMP synthesis in both B- and T-cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A140T864", "url": "https://www.uniprot.org/uniprotkb/A0A140T864#function" }, { "database": "UniProtKB", "id": "ARBA00094362", "url": "https://www.uniprot.org/uniprotkb/ARBA00094362#function" }, { "database": "UniProtKB", "id": "A0A3Q1M6Y3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6Y3#function" }, { "database": "UniProtKB", "id": "A0ABI0P529", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529#function" } ] }, { "annotation": "Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.", "evidence": [ { "database": "UniProtKB", "id": "A0A140T864", "url": "https://www.uniprot.org/uniprotkb/A0A140T864#function" }, { "database": "UniProtKB", "id": "PIRNR039050", "url": "https://www.uniprot.org/uniprotkb/PIRNR039050#function" }, { "database": "UniProtKB", "id": "A0A3Q1M6Y3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6Y3#function" }, { "database": "UniProtKB", "id": "A0ABI0P529", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P529", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ADCY7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529", "locus": { "chromosome": "18", "start_pos": 18720625, "end_pos": 18655907, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006208", "url": "https://www.ensembl.org/id/ENSBTAG00000006208" } ] } } ], "crossref": [ { "id": "ENSBTAG00000006208", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006208", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07302", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07302", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "281603", "url": "https://www.ncbi.nlm.nih.gov/gene/281603", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018297", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018297", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:281603", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281603", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A140T864", "url": "https://www.orthodb.org/?gene=A0A140T864", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M6Y3", "url": "https://www.orthodb.org/?gene=A0A3Q1M6Y3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45627", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45627", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45627:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45627:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00211", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00211", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06327", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06327", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005218496", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005218496", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "15389", "url": "https://www.rhea-db.org/rhea/15389", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "35655", "url": "https://www.rhea-db.org/rhea/35655", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A140T864", "url": "https://www.uniprot.org/uniprotkb/A0A140T864", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T864-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T864-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M6Y3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M6Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P529", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P529-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPRPWGFLRGPLGVPRWRMPAKGRYFLNEGEEGPDQDALYEKYRLTSQHGPLLLMLLLVAIAACTTLIVITFSYGDPSRHRAVLGTAFFTLAMFVLLYALVYVECLDRRGLRISALLIWACLVTLGYVLVFDFDSPRKDTCVLGQVPFFLFVVFVVYTLLPFSMWGAVTAGLVSSISHLLVLAMHQEDFTSPVGLKLLATAVVFVCGNLTGAFHKHHMQDASHDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAHISMGMKLAIIERLKERGDRRYLPDNNFHNLYVKRHQNVSILYADIVGFTRLASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPNHARNCVKMGLDMCEAIKQVREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEATLKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPQPSQHNSKNKGDATLKMRASVRMTRYLESWGAARPFAHLNQRESVSSSETLVSHGRRPKAVPLRRHRTPDRSASPKGRSEDDSYDDEMLSAIEGLSSTRPCCSKSDDFSTFGSIFLEKGFEREYRLAPIPRVRYYFACASLVFVFILLIHVLLLYSMKTLGVSFGLVACVLGLVLGLCFADVFLRCCPALGKLRAIAESVETQPLLRVSLAILTIGSLLVIAVVNLPLMPFRDRGLTAGNETGLRAVSGWEMSPCYLLPYYTCSCILAFIACSVFLRMSLELKVVLLTVALVAYLVLFNVYPSWQWDCCGHSLGNLTGTNGTLSSSSSCSWHLKTMTNFYLVLFYTTLIMLSRQIDYYCRLDCLWKKKFKKEHEEFETMENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVPSGPENQDLERQHAHIGIMVEFSTALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSCECRGLIDVKGKGELRTYFVCTDTAKFQGLGLN", "length": 1097, "header": "tr|A0ABI0P529-1|A0ABI0P529_BOVIN Isoform 1 of Adenylate cyclase type 7 OS=Bos taurus OX=9913 GN=ADCY7 PE=3 SV=1 CANONICAL=A0ABI0P529-1" }, "isoforms": [ { "isoform_ac": "A0A140T864-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529/entry#A0A140T864-1", "sequence": { "sequence": "MLPRPWGFLRGPLGVPRWRMPAKGRYFLNEGEEGPDQDALYEKYRLTSQHGPLLLMLLLVAIAACTTLIVITFSYGDPSRHRAVLGTAFFTLAMFVLLYALVYVECLDRRGLRISALLIWACLVTLGYVLVFDFDSPRKDTCVLGQVPFFLFVVFVVYTLLPFSMWGAVTAGLVSSISHLLVLAMHQEDFTSPVGLKLLATAVVFVCGNLTGAFHKHHMQDASHDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAHISMGMKLAIIERLKERGDRRYLPDNNFHNLYVKRHQNVSILYADIVGFTRLASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPNHARNCVKMGLDMCEAIKQVREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEATLKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPQPSQHNSKNKGDATLKMRASVRMTRYLESWGAARPFAHLNQRESVSSSETLVSHGRRPKAVPLRRHRTPDRSASPKGRSEDDSYDDEMLSAIEGLSSTRPCCSKSDDFSTFGSIFLEKGFEREYRLAPIPRVRYYFACASLVFVFILLIHVLLLYSMKTLGVSFGLVACVLGLVLGLCFADVFLRCCPALGKLRAIAESVETQPLLRVSLAILTIGSLLVIAVVNLPLMPFRDRGLTAGNETGLRAVSGWEMSPCYLLPYYTCSCILAFIACSVFLRMSLELKVVLLTVALVAYLVLFNVYPSWQWDCCGHSLGNLTGTNGTLSSSSCSWHLKTMTNFYLVLFYTTLIMLSRQIDYYCRLDCLWKKKFKKEHEEFETMENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVPSGPENQDLERQHAHIGIMVEFSTALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSCECRGLIDVKGKGELRTYFVCTDTAKFQGLGLN", "length": 1096, "header": "tr|A0A140T864-1|A0ABI0P529_BOVIN Computationally mapped isoform of Adenylate cyclase type 7 OS=Bos taurus OX=9913 GN=ADCY7 PE=3 SV=3 CANONICAL=A0ABI0P529-1" }, "locus": { "chromosome": "18", "start_pos": 18718246, "end_pos": 18691744, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008153.5", "url": "https://www.ensembl.org/id/ENSBTAT00000008153.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008153.4", "url": "https://www.ensembl.org/id/ENSBTAP00000008153.4" } ] } }, { "isoform_ac": "A0A3Q1M6Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529/entry#A0A3Q1M6Y3-1", "sequence": { "sequence": "MLPRPWGFLRGPLGVPRWRMPAKGRYFLNEGEEGPDQDALYEKYRLTSQHGPLLLMLLLVAIAACTTLIVITFSYGDPSRHRAVLGTAFFTLAMFVLLYALVYVECLDRRGLRISALLIWACLVTLGYVLVFDFDSPRKDTCVLGQLLATAVVFVCGNLTGAFHKHHMQDASHDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAHISMGMKLAIIERLKERGDRRYLPDNNFHNLYVKRHQNVSILYADIVGFTRLASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPNHARNCVKMGLDMCEAIKQVREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEATLKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPQPSQHNSKNKGDATLKMRASVRMTRYLESWGAARPFAHLNQRESVSSSETLVSHGRRPKAVPLRRHRTPDRSASPKGRSEDDSYDDEMLSAIEGLSSTRPCCSKSDDFSTFGSIFLEKGFEREYRLAPIPRVRYYFACASLVFVFILLIHVLLLYSMKTLGVSFGLVACVLGLVLGLCFADVFLRCCPALGKLRAIAESVETQPLLRVSLAILTIGSLLVIAVVNLPLMPFRDRGLTAGNETGLRAVSGWEMSPCYLLPYYTCSCILAFIACSVFLRMSLELKVVLLTVALVAYLVLFNVYPSWQWDCCGHSLGNLTGTNGTLSSSSCSWHLKTMTNFYLVLFYTTLIMLSRQIDYYCRLDCLWKKKFKKEHEEFETMENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVPSGPENQDLERQHAHIGIMVEFSTALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSCECRGLIDVKGKGELRTYFVCTDTAKFQGLGLN", 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"length": 1097, "header": "tr|A0ABI0P529-1|A0ABI0P529_BOVIN Isoform 1 of Adenylate cyclase type 7 OS=Bos taurus OX=9913 GN=ADCY7 PE=3 SV=1 CANONICAL=A0ABI0P529-1" }, "locus": { "chromosome": "18", "start_pos": 18718246, "end_pos": 18691744, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136385.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136385.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106774.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106774.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:281603", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281603", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "adenylate cyclase activity", "id": "GO:0004016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004016", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P529", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P529", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P529", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P529", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cAMP biosynthetic process", "id": "GO:0006171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006171", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P529", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P529", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P529" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 719, "end_pos": 721, "annotation": "n_glycosylation_sequon" }, { "start_pos": 794, "end_pos": 796, "annotation": "n_glycosylation_sequon" }, { "start_pos": 799, "end_pos": 801, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15389", "name": "", "equation": "ATP = 3',5'-cyclic AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TFX0-1", "A0A3Q1MA58-1", "E1B9K3-1", "E1BQ12-1", "E1BHU9-1", "A0ABI0P283-1", "P19754-1", "A0ABI0P529-1", "Q29450-1", "E1BM79-1", "A0AAA9U028-1" ], "evidence": [ { "id": "15389", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15389" } ] }, { "id": "35655", "name": "", "equation": "2 ATP = 3',3'-c-di-AMP + 2 diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q29450-1", "A0ABI0P529-1" ], "evidence": [ { "id": "35655", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/35655" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MA58", "gene_name": "ADCY4", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": 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} ] } ] }, { "uniprot_ac": "E1B9K3", "gene_name": "ADCY6", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "E1B9K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9K3" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "E1B9K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9K3" } ] } ] }, { "uniprot_ac": "E1BHU9", "gene_name": "ADCY5", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "E1BHU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHU9" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "E1BHU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHU9" } ] } ] }, { "uniprot_ac": "E1BM79", "gene_name": "ADCY9", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { 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3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "4.6.1.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.1" }, { "id": "4.6.1.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.6.1.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 209, "end_pos": 211 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 719, "end_pos": 721 }, { "start_pos": 794, "end_pos": 796 }, { "start_pos": 799, "end_pos": 801 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, 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hydroxylase EGLN2 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421733" }, "gene_names": [ { "name": "EGLN2", "type": "recommended", "evidence": [ { "id": "A0ABI0P3Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1" } ] }, { "name": "EGLN2", "type": "synonym", "evidence": [ { "id": "NP_001421733", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421733" } ] } ], "protein_names": [ { "name": "hypoxia-inducible factor-proline dioxygenase", "type": "recommended", "evidence": [ { "id": "A0ABI0P3Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1/entry#names_and_taxonomy" } ] }, { "name": "1.14.11.29", "type": "synonym", "evidence": [ { "id": "A0ABI0P3Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1/entry#names_and_taxonomy" } ] }, { "name": "prolyl hydroxylase EGLN2 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001421733", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421733" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EGLN2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1", "locus": { "chromosome": "18", "start_pos": 50056732, "end_pos": 50048840, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017996", "url": "https://www.ensembl.org/id/ENSBTAG00000017996" } ] } } ], "crossref": [ { "id": "ENSBTAG00000017996", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017996", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "536763", "url": "https://www.ncbi.nlm.nih.gov/gene/536763", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051559", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051559", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AWQTACP", "url": "https://omabrowser.org/oma/group/AWQTACP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LUX2", "url": "https://www.orthodb.org/?gene=A0A3Q1LUX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MX98", "url": "https://www.orthodb.org/?gene=F1MX98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12907", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12907", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12907:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12907:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1234176", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1234176", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001421733", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421733", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "48400", "url": "https://www.rhea-db.org/rhea/48400", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LUX2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3Q1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MX98", "url": "https://www.uniprot.org/uniprotkb/F1MX98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MX98-1", "url": "https://www.uniprot.org/uniprotkb/F1MX98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSPCQPQPLSQALPQLPGSVSEPLEPSRARMGVESYLPCPLLSYHRPGAPTEASAGSGTPRATATSTTGSPLREGFGAQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRKWAEDGGDAPAPSKRPWARQENQEAEGEGCSSGSGEASAGLREEVLPAAPERLALDYIVPCMRYYGICVKDSFLGAALGGQVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCQSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPTTPT", "length": 399, "header": "tr|A0ABI0P3Q1-1|A0ABI0P3Q1_BOVIN Isoform 1 of hypoxia-inducible factor-proline dioxygenase OS=Bos taurus OX=9913 GN=EGLN2 PE=4 SV=1 CANONICAL=A0ABI0P3Q1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LUX2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1/entry#A0A3Q1LUX2-1", "sequence": { "sequence": "MDSPCQPQPLSQALPQLPGSVSEPLEPSRARMGVESYLPCPLLSYHRPGAPTEASAGSGTPRATATSTTGSPLREGFGAQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRKWAEDGGDAPAPSKRPWARQENQEAEGEGCSSGSGEASAGLREEVLPAAPERLALDYIVPCMRYYGICVKDSFLGAALGGQVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCQSIGALMAHVDAVIRHCAGRLGSYVINGRTKTLKRGAAIHSPASVSEPWWGQQPRDVCSWALEQADKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPTTPT", "length": 435, "header": "tr|A0A3Q1LUX2-1|A0ABI0P3Q1_BOVIN Computationally mapped isoform of hypoxia-inducible factor-proline dioxygenase OS=Bos taurus OX=9913 GN=EGLN2 PE=4 SV=2 CANONICAL=A0ABI0P3Q1-1" }, "locus": { "chromosome": "18", "start_pos": 50056155, "end_pos": 50049039, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072600.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072600.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061162.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061162.2" } ] } }, { "isoform_ac": "A0ABI0P3Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1/entry#A0ABI0P3Q1-1", "sequence": { "sequence": "MDSPCQPQPLSQALPQLPGSVSEPLEPSRARMGVESYLPCPLLSYHRPGAPTEASAGSGTPRATATSTTGSPLREGFGAQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRKWAEDGGDAPAPSKRPWARQENQEAEGEGCSSGSGEASAGLREEVLPAAPERLALDYIVPCMRYYGICVKDSFLGAALGGQVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCQSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPTTPT", "length": 399, "header": "tr|A0ABI0P3Q1-1|A0ABI0P3Q1_BOVIN Isoform 1 of hypoxia-inducible factor-proline dioxygenase OS=Bos taurus OX=9913 GN=EGLN2 PE=4 SV=1 CANONICAL=A0ABI0P3Q1-1" }, "locus": { "chromosome": "18", "start_pos": 50056155, "end_pos": 50049039, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139304.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139304.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105825.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105825.1" } ] } }, { "isoform_ac": "F1MX98-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1/entry#F1MX98-1", "sequence": { "sequence": "MDSPCQPQPLSQALPQLPGSVSEPLEPSRARMGVESYLPCPLLSYHRPGAPTEASAGSGTPRATATSTTGSPLREGFGAQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRKWAEDGGDAPAPSKRPWARQENQEAEGEGCSSGSGEASAGLREEVLPAAPERLALDYIVPCMRYYGICVKDSFLGAALGGQVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCQSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATSIRTERGPSARVTADYAHLVASPRAAWTDSLPWLQESPGPRCCQSRCLLLPRHHHCF", "length": 415, "header": "tr|F1MX98-1|A0ABI0P3Q1_BOVIN Computationally mapped isoform of hypoxia-inducible factor-proline dioxygenase OS=Bos taurus OX=9913 GN=EGLN2 PE=4 SV=2 CANONICAL=A0ABI0P3Q1-1" }, "locus": { "chromosome": "18", "start_pos": 50056271, "end_pos": 50049039, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023945.6", "url": "https://www.ensembl.org/id/ENSBTAT00000023945.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023945.4", "url": "https://www.ensembl.org/id/ENSBTAP00000023945.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-1234176", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1234176", "resource": "Reactome", "description": "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6AYU4-1", "protein_name": "Prolyl hydroxylase EGLN2", "gene_name": "Egln2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSPCQPQALNQALPQLPGSVSESLEPSRARMGVESYLPCPLLPSYHRSGASGEASAGNGTPRTTATATTTTASPLREGFGGQDGGELWPLQSEGAAALVTKECQRLAAQGARPEAPKRKWAKDGGDAPSPSKRPWARQENQEAKGESGVGCDSGGGSSNSTTHSSGEASSRLREEAQPSAPERLALDYIVPCMRYYGICVKDNFLGAVLGGRVLAEVEALKWGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGNYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAARDKYQLASGQKGVQVPVSQPATPT", "length": 415 }, "evidence": [ { "id": "A0ABI0P3Q1", "url": "https://omabrowser.org/oma/group/A0ABI0P3Q1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91YE2-1", "protein_name": "Prolyl hydroxylase EGLN2", "gene_name": "Egln2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSPCQPQALNQALPQLPGSVSESLESSRARMGVESYLPCPLLPAYHRPGASGEASAGNGTPRTTATATTTTASPLREGFGGQDGGELWPLQSEGAAALVTKECQRLAAQGARPEAPKRKWAKDGGDAPSPSKRPWARQENQEAKGESGMGCDSGASNSSSSSSNTTSSSGEASARLREEVQPSAPERLALDYIVPCMRYYGICVKDNFLGAVLGGRVLAEVEALKWGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGNYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAARDKYQLASGQKGVQVPVSQPTTPT", "length": 419 }, "evidence": [ { "id": "A0ABI0P3Q1", "url": "https://omabrowser.org/oma/group/A0ABI0P3Q1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96KS0-1", "protein_name": "Prolyl hydroxylase EGLN2", "gene_name": "EGLN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSPCQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAGSGTPRATATSTTASPLRDGFGGQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRKWAEDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALDYIVPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT", "length": 407 }, "evidence": [ { "id": "A0ABI0P3Q1", "url": "https://omabrowser.org/oma/group/A0ABI0P3Q1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1" } ], "pmid": "" }, { "name": "regulation of neuron apoptotic process", "id": "GO:0043523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043523", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1" } ], "pmid": "" }, { "name": "L-ascorbic acid binding", "id": "GO:0031418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031418", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1" } ], "pmid": "" }, { "name": "peptidyl-proline 4-dioxygenase activity", "id": "GO:0031545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031545", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1" } ], "pmid": "" }, { "name": "hypoxia-inducible factor-proline dioxygenase activity", "id": "GO:0160082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160082", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Q1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48400", "name": "", "equation": "L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABI0P3Q1-1", "A0AAA9SDY7-1", "A0A3Q1M2B6-1", "F1N3W9-1" ], "evidence": [ { "id": "48400", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48400" } ] }, { "id": "R-BTA-1234165", "name": "Nuclear PHD1,3 hydroxylates proline residues on HIF3A", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-BTA-9717059" ], "output_participant_list": [ "R-BTA-1234140" ], "enzyme_list": [ "A0ABI0P3Q1-1" ], "evidence": [ { "id": "R-BTA-1234165", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1234165" } ] }, { "id": "R-BTA-1234181", "name": "Nuclear PHD1,3 hydroxylates proline residues on HIF1A", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-BTA-1234135" ], "output_participant_list": [ "R-BTA-1234105" ], "enzyme_list": [ "A0ABI0P3Q1-1" ], "evidence": [ { "id": "R-BTA-1234181", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1234181" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-1234105", "participant_name": "HIF1A [nucleoplasm]", "crossref": [ { "id": "NP_776764.2", "database": "RefSeq", "url": "" }, { "id": "29848", "database": "VGNC", "url": "" }, { "id": "A0JND0", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-BTA-1234135", "participant_name": "HIF1A [nucleoplasm]", "crossref": [ { "id": "A0JND0", "database": "UniProt", "url": "" }, { "id": "NP_776764.2", "database": "RefSeq", "url": "" }, { "id": "29848", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-1234140", "participant_name": "HIF3A [nucleoplasm]", "crossref": [ { "id": "ENSBTAG00000018948", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000025217", "database": "ENSEMBL", "url": "" }, { "id": "F6RL11", "database": "UniProt", "url": "" }, { "id": "29850", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000025217", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-BTA-9717059", "participant_name": "HIF3A [nucleoplasm]", "crossref": [ { "id": "F6RL11", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000018948", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000025217", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000025217", "database": "ENSEMBL", "url": "" }, { "id": "29850", "database": "VGNC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1M2B6", "gene_name": "EGLN1", "activity": [ { "ec_number": "1.14.11.29", "activity": "L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2.", "evidence": [ { "id": "A0A3Q1M2B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2B6" } ] }, { "ec_number": "1.14.11.29", "activity": "", "evidence": [ { "id": "A0A3Q1M2B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2B6" } ] } ] }, { "uniprot_ac": "A0AAA9SDY7", "gene_name": "EGLN3", "activity": [ { "ec_number": "1.14.11.29", "activity": "L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2.", "evidence": [ { "id": "A0AAA9SDY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDY7" } ] }, { "ec_number": "1.14.11.29", "activity": "", "evidence": [ { "id": "A0AAA9SDY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDY7" } ] } ] }, { "uniprot_ac": "A0ABI0P3Q1", "gene_name": "EGLN2", "activity": [ { "ec_number": "1.14.11.29", "activity": "L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2.", "evidence": [ { "id": "A0ABI0P3Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1" } ] }, { "ec_number": "1.14.11.29", "activity": "", "evidence": [ { "id": "A0ABI0P3Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1" } ] } ] }, { "uniprot_ac": "F1N3W9", "gene_name": "P4HTM", "activity": [ { "ec_number": "1.14.11.29", "activity": "L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2.", "evidence": [ { "id": "F1N3W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W9" } ] }, { "ec_number": "1.14.11.29", "activity": "", "evidence": [ { "id": "F1N3W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W9" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P3Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Q1" }, { "id": "PS51471", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51471" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fe2OG dioxygenase", "eco_id": "ECO_0000259", "start_pos": 270, "end_pos": 368, "start_aa": "Gly", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.11.29", "ec_name": "L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2.", "evidence": [ { "id": "1.14.11.29", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.29" }, { "id": "1.14.11.29", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.29" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P2Z2-1", "uniprot_ac": "A0ABI0P2Z2", "uniprot_id": "A0ABI0P2Z2_BOVIN", "mass": { "chemical_mass": 41002.0, "monoisotopic_mass": 41002.0 }, "refseq": { "ac": "XP_059731816", "name": "membrane cofactor protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059731816" }, "gene_names": [ { "name": "LOC518224", "type": "recommended", "evidence": [ { "id": "A0ABI0P2Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2" } ] }, { "name": "LOC518224", "type": "synonym", "evidence": [ { "id": "XP_059731816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059731816" } ] } ], "protein_names": [ { "name": "Membrane cofactor protein", "type": "recommended", "evidence": [ { "id": "A0ABI0P2Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2/entry#names_and_taxonomy" } ] }, { "name": "membrane cofactor protein", "type": "synonym", "evidence": [ { "id": "XP_059731816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059731816" } ] } ], "function": [ { "annotation": "Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1M765", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M765#function" }, { "database": "UniProtKB", "id": "PIRNR037971", "url": "https://www.uniprot.org/uniprotkb/PIRNR037971#function" }, { "database": "UniProtKB", "id": "A0ABI0P2Z2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2Z2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC518224", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000052901", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000052901", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "518224", "url": "https://www.ncbi.nlm.nih.gov/gene/518224", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325:SF521", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325:SF521", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059731816", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059731816", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M765", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M765", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M765-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M765-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2Z2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLVVLVLLLPSVSDACGDPPRFETMRLRGAPKPRYGPGERVQYDCRLGFKPIIPLRPRSAVCEDDNTWSALEEACTRKSCPNLGDPVNGQVYFVNGSVLFGSQAHFVCNQGFYLIGARILYCEISENNVNWNDDSPICEKILCSTPGNIKNGRFTVYKDEYQYNEIVIYMCDPSNGPDEYSLVGESTLICVDYDRWSSDPPECKVVKCDYPVVEHGMILSGFRRKFYYKAQVVFKCNQGFYLHGSSTIVCNANSVWEPKLPTCTKVPVAVPTEPSTTHASGPRPNTTTAPSSTGPRPNTTTVPSSTGLHPATTATSSHTAYVSPTVDLEPEYFEDFDAAVIAVVILSVLIAAGIVTACLYKYSAERTERVH", "length": 372, "header": "tr|A0ABI0P2Z2-1|A0ABI0P2Z2_BOVIN Isoform 1 of Membrane cofactor protein OS=Bos taurus OX=9913 GN=LOC518224 PE=4 SV=1 CANONICAL=A0ABI0P2Z2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M765-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2/entry#A0A3Q1M765-1", "sequence": { "sequence": "MLLVVLVLLLPSVSDACGDPPRFETMRLRGAPKPRYGPGERVQYDCRLGFKPIIPLRPRSAVCEDDNTWSALEEACTRKSCPNLGDPVNGQVYFVNGSVLFGSQAHFVCNQGFYLIGARILYCEISENNVNWNDDSPICEKILCSTPGNIKNGRFTVYKDEYQYNEIVIYMCDPSNGPDEYSLVGESTLICVDYDRWSSDPPECKVVKCDYPVVEHGMILSGFRRKFYYKAQVVFKCNQGFYLHGSSTIVCNANSVWEPKLPTCTKVPVAVPTEPSTTHASGPRPNTTTVPSSTGLHPATTATSSHTAYVSPTVDLEPEYFEDFGIILVINNLAL", "length": 335, "header": "tr|A0A3Q1M765-1|A0ABI0P2Z2_BOVIN Computationally mapped isoform of Membrane cofactor protein OS=Bos taurus OX=9913 GN=LOC518224 PE=4 SV=3 CANONICAL=A0ABI0P2Z2-1" }, "locus": { "chromosome": "16", "start_pos": 75736018, "end_pos": 75682705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068922.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068922.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066196.3", "url": "https://www.ensembl.org/id/ENSBTAP00000066196.3" } ] } }, { "isoform_ac": "A0ABI0P2Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2/entry#A0ABI0P2Z2-1", "sequence": { "sequence": "MLLVVLVLLLPSVSDACGDPPRFETMRLRGAPKPRYGPGERVQYDCRLGFKPIIPLRPRSAVCEDDNTWSALEEACTRKSCPNLGDPVNGQVYFVNGSVLFGSQAHFVCNQGFYLIGARILYCEISENNVNWNDDSPICEKILCSTPGNIKNGRFTVYKDEYQYNEIVIYMCDPSNGPDEYSLVGESTLICVDYDRWSSDPPECKVVKCDYPVVEHGMILSGFRRKFYYKAQVVFKCNQGFYLHGSSTIVCNANSVWEPKLPTCTKVPVAVPTEPSTTHASGPRPNTTTAPSSTGPRPNTTTVPSSTGLHPATTATSSHTAYVSPTVDLEPEYFEDFDAAVIAVVILSVLIAAGIVTACLYKYSAERTERVH", "length": 372, "header": "tr|A0ABI0P2Z2-1|A0ABI0P2Z2_BOVIN Isoform 1 of Membrane cofactor protein OS=Bos taurus OX=9913 GN=LOC518224 PE=4 SV=1 CANONICAL=A0ABI0P2Z2-1" }, "locus": { "chromosome": "16", "start_pos": 75736018, "end_pos": 75678258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139874.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139874.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105572.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105572.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 326, "start_aa": "Thr", "end_pos": 326, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr326", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2Z2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2Z2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2Z2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2" } ], "pmid": "" }, { "name": "inner acrosomal membrane", "id": "GO:0002079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002079", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2Z2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2Z2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2" } ], "pmid": "" }, { "name": "negative regulation of complement activation, classical pathway", "id": "GO:0045959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045959", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2Z2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2" } ], "pmid": "" }, { "name": "T cell mediated immunity", "id": "GO:0002456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002456", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2Z2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P2Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Z2" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 78, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 326 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 286, "end_pos": 288 }, { "start_pos": 299, "end_pos": 301 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P0F0-1", "uniprot_ac": "A0ABI0P0F0", "uniprot_id": "A0ABI0P0F0_BOVIN", "mass": { "chemical_mass": 25007.0, "monoisotopic_mass": 25007.0 }, "refseq": { "ac": "XP_002689314", "name": "NEDD4 family-interacting protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689314" }, "gene_names": [ { "name": "NDFIP1", "type": "recommended", "evidence": [ { "id": "A0ABI0P0F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0" } ] }, { "name": "NDFIP1", "type": "synonym", "evidence": [ { "id": "XP_002689314", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689314" } ] } ], "protein_names": [ { "name": "NEDD4 family-interacting protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002689314", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689314" } ] }, { "name": "Nedd4 family interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0ABI0P0F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NDFIP1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0", "locus": { "chromosome": "7", "start_pos": 53202853, "end_pos": 53148918, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047747", "url": "https://www.ensembl.org/id/ENSBTAG00000047747" } ] } } ], "crossref": [ { "id": "ENSBTAG00000047747", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047747", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22305", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22305", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "541196", "url": "https://www.ncbi.nlm.nih.gov/gene/541196", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:541196", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541196", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ASMVKWT", "url": "https://omabrowser.org/oma/group/ASMVKWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MAX3", "url": "https://www.orthodb.org/?gene=A0A3Q1MAX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MXI8", "url": "https://www.orthodb.org/?gene=G3MXI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13396:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13396:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002689314", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689314", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M841", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M841", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M841-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M841-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAX3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDN5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0F0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0F0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXI8", "url": "https://www.uniprot.org/uniprotkb/G3MXI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXI8-1", "url": "https://www.uniprot.org/uniprotkb/G3MXI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALALAALAAVEPACGNRYQQLQNEEEPGEPEQAAGDAPPPYSSISAESAAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEEFAGREEFDDPDQMRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPENFSNLPRTRVLFIY", "length": 221, "header": "tr|A0ABI0P0F0-1|A0ABI0P0F0_BOVIN Isoform 1 of Nedd4 family interacting protein 1 OS=Bos taurus OX=9913 GN=NDFIP1 PE=4 SV=1 CANONICAL=A0ABI0P0F0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M841-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0/entry#A0A3Q1M841-1", "sequence": { "sequence": "MALALAALAAVEPACGNRYQQLQNEEEPGEPEQAAGDAPPPYSSISAESAAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEEFAGREEFDDPDQMRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLDVFWRRPSCIYEFSPKKQENTCRK", "length": 211, "header": "tr|A0A3Q1M841-1|A0ABI0P0F0_BOVIN Computationally mapped isoform of Nedd4 family interacting protein 1 OS=Bos taurus OX=9913 GN=NDFIP1 PE=4 SV=1 CANONICAL=A0ABI0P0F0-1" }, "locus": { "chromosome": "7", "start_pos": 53201849, "end_pos": 53151947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078235.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078235.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064569.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064569.1" } ] } }, { "isoform_ac": "A0A3Q1MAX3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0/entry#A0A3Q1MAX3-1", "sequence": { "sequence": "MECRKARAEARGPARIGCSGLSAWGWPEGRLQNEEEPGEPEQAAGDAPPPYSSISAESAAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEEFAGREEFDDPDQMRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPENFSNLPRTRVLFIY", "length": 230, "header": "tr|A0A3Q1MAX3-1|A0ABI0P0F0_BOVIN Computationally mapped isoform of Nedd4 family interacting protein 1 OS=Bos taurus OX=9913 GN=NDFIP1 PE=4 SV=2 CANONICAL=A0ABI0P0F0-1" }, "locus": { "chromosome": "7", "start_pos": 53195791, "end_pos": 53116761, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069512.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069512.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071194.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071194.2" } ] } }, { "isoform_ac": "A0A3Q1MDN5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0/entry#A0A3Q1MDN5-1", "sequence": { "sequence": "MALALAALAAVEPACGNRYQQLQNEEEPGEPEQAAGDAPPPYSSISAESAAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEEFAGREEFDDPDQMRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRLSPVSQRIYQLCKSSEDARKFLKSPQDQSSLYLLKMFSGEGLPAFMNSLPRSKRTPAGSESRCGTQRNHHLL", "length": 218, "header": "tr|A0A3Q1MDN5-1|A0ABI0P0F0_BOVIN Computationally mapped isoform of Nedd4 family interacting protein 1 OS=Bos taurus OX=9913 GN=NDFIP1 PE=4 SV=2 CANONICAL=A0ABI0P0F0-1" }, "locus": { "chromosome": "7", "start_pos": 53201889, "end_pos": 53151947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085973.3", "url": "https://www.ensembl.org/id/ENSBTAT00000085973.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069053.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069053.2" } ] } }, { "isoform_ac": "A0ABI0P0F0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0/entry#A0ABI0P0F0-1", "sequence": { "sequence": "MALALAALAAVEPACGNRYQQLQNEEEPGEPEQAAGDAPPPYSSISAESAAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEEFAGREEFDDPDQMRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPENFSNLPRTRVLFIY", "length": 221, "header": "tr|A0ABI0P0F0-1|A0ABI0P0F0_BOVIN Isoform 1 of Nedd4 family interacting protein 1 OS=Bos taurus OX=9913 GN=NDFIP1 PE=4 SV=1 CANONICAL=A0ABI0P0F0-1" }, "locus": { "chromosome": "7", "start_pos": 53195791, "end_pos": 53151947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150694.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150694.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104490.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104490.1" } ] } }, { "isoform_ac": "G3MXI8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0/entry#G3MXI8-1", "sequence": { "sequence": "MELKSGEELQNEEEPGEPEQAAGDAPPPYSSISAESAAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEEFAGREEFDDPDQMRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPENFSNLPRTRVLFIY", "length": 208, "header": "tr|G3MXI8-1|A0ABI0P0F0_BOVIN Computationally mapped isoform of Nedd4 family interacting protein 1 OS=Bos taurus OX=9913 GN=NDFIP1 PE=4 SV=2 CANONICAL=A0ABI0P0F0-1" }, "locus": { "chromosome": "7", "start_pos": 53195791, "end_pos": 53169452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064420.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064420.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054255.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054255.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:541196", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541196", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B0W0-1", "protein_name": "Nedd4 family interacting protein 1", "gene_name": "NDFIP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALALAALAAVEPACGSRYQQLQNEEEPGEPEQAAGDAPPPYSSISAESAVYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEDFVGRDDFDDADQMRIGNDGVFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPETFSNLPRTRVLFIY", "length": 221 }, "evidence": [ { "id": "A0ABI0P0F0", "url": "https://omabrowser.org/oma/group/A0ABI0P0F0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6DGP4-1", "protein_name": "NEDD4 family-interacting protein 1-like", "gene_name": "ndfip1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEPSGRYQQLPCEEEPEAGPQVAADAPPPYSSIAADSAAFFDYKDDAAFPNPPSYNVATSLPSYDEAERTKTETSVPLVSGRDDDFVARDDFEDADQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKIRKMADSFSTLPRTRVLFIY", "length": 210 }, "evidence": [ { "id": "A0ABI0P0F0", "url": "https://omabrowser.org/oma/group/A0ABI0P0F0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8R0W6-1", "protein_name": "NEDD4 family-interacting protein 1", "gene_name": "Ndfip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALALAALAAVEPACGSGYQQLQNEEEPGEPEQTAGDAPPPYSSITAESAAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKTEATIPLVPGRDEDFVGRDDFDDTDQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPETFSNLPRTRVLFIY", "length": 221 }, "evidence": [ { "id": "A0ABI0P0F0", "url": "https://omabrowser.org/oma/group/A0ABI0P0F0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BT67-1", "protein_name": "NEDD4 family-interacting protein 1", "gene_name": "NDFIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALALAALAAVEPACGSRYQQLQNEEESGEPEQAAGDAPPPYSSISAESAAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGRDEDFVGRDDFDDADQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPETFSNLPRTRVLFIY", "length": 221 }, "evidence": [ { "id": "A0ABI0P0F0", "url": "https://omabrowser.org/oma/group/A0ABI0P0F0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0" } ], "pmid": "" }, { "name": "metal ion transport", "id": "GO:0030001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030001", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0" } ], "pmid": "" }, { "name": "positive regulation of protein ubiquitination", "id": "GO:0031398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031398", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "WW domain binding", "id": "GO:0050699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050699", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 208, "end_pos": 210 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P0M3-1", "uniprot_ac": "A0ABI0P0M3", "uniprot_id": "A0ABI0P0M3_BOVIN", "mass": { "chemical_mass": 88245.0, "monoisotopic_mass": 88245.0 }, "refseq": {}, "gene_names": [ { "name": "DISC1", "type": "recommended", "evidence": [ { "id": "A0ABI0P0M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ] } ], "protein_names": [ { "name": "DISC1 scaffold protein", "type": "synonym", "evidence": [ { "id": "A0ABI0P0M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DISC1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3", "locus": { "chromosome": "28", "start_pos": 4868089, "end_pos": 4454726, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000050839", "url": "https://www.ensembl.org/id/ENSBTAG00000050839" } ] } } ], "crossref": [ { "id": "ENSBTAG00000050839", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000050839", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613555", "url": "https://www.ncbi.nlm.nih.gov/gene/613555", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613555", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613555", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WTGKEEM", "url": "https://omabrowser.org/oma/group/WTGKEEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MBR1", "url": "https://www.orthodb.org/?gene=A0A3Q1MBR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14332", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14332", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14332:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14332:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28234", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28234", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MBR1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MBR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TD50", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TD50-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0M3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSAAGPRIGFLSPPVGAPFRAQGGACGKESHHLESRAGPCGLDPGGQWRGRSVGSLIPRSTATSALTVGHRGPALTAAKGSPGLLGSQPRAGTALPNRLSRLCGPRATGCRGELPSTDTREAPSPCREAWNKGCPSPEDMSDTSCSLGSGPQAPAIPASSQDVFTSSFSFIRLSLGSAGERGEAEGCPPSREAEGPHQSLEEMEAKAASSGGPHDHPRLLSLPFTLKASQGLADATQTSGGSRGLECQTLPLLDTDAASSCSLDPLWFEASSSADAQRWDPLLSRCEPALLHCLQGQRRRLEVKSLRLKLQKLQDKAIEEDDYDKAEMIQQRLEALEKERSSLHFQLPSQQPALSALLGHLGAQAQASLRWAAQRAGGDDPQARLRMDPKTLEAAAQDSLRVSITRRDWLLREKQQLQKEIETLQARMSVLEAKDQQLRREIEEQERLLPWQGCDLVGGLSLGELQEVTKTLQDTLALAEQIPLHAEPPETIRSLQERIKSLSLSLKEITAKVCMSERLCSALRKKVNDIETQLPALFEAKMLAISGNHFYTAKELTEEIRSLTLEREALEGLLHKLLVLSSRNVQKLGSVKEDYSRLRQELDQGRAAYETSVKVNTMKYMEMLEEKLHSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLFADERQTDDLGGGTYTMALATPLRSHLEDGRKNPLQAFEEWTVHLTPSPHCASSEQKEESYIFSAELGEKCETIGKKLLYLEDQLHVAIHSHDEDLIHSLKGELQMVKETLQAMALQLQPAKEAGEREAAASCVTAGIREAQS", "length": 807, "header": "tr|A0ABI0P0M3-1|A0ABI0P0M3_BOVIN Isoform 1 of DISC1 scaffold protein OS=Bos taurus OX=9913 GN=DISC1 PE=4 SV=1 CANONICAL=A0ABI0P0M3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MBR1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3/entry#A0A3Q1MBR1-1", "sequence": { "sequence": "MLGGGPQGAPAGGGRGHRAGSQDCSPPAASFRRRRLARRPGYMRSAAGPRIGFLSPPVGAPFRAQGGACGKESHHLESRAGPCGLDPGGQWRGRSVGSLIPRSTATSALTVGHRGPALTAAKGSPGLLGSQPRAGTALPNRLSRLCGPRATGCRGELPSTDTREAPSPCREAWNKGCPSPEDMSDTSCSLGSGPQAPAIPASSQDVFTSSFSFIRLSLGSAGERGEAEGCPPSREAEGPHQSLEEMEAKAASSGGPHDHPRLLSLPFTLKASQGLADATQTSGGSRGLECQTLPLLDTDAASSCSLDPLWFEASSSADAQRWDPLLSRCEPALLHCLQGQRRRLEVKSLRLKLQKLQDKAIEEDDYDKAEMIQQRLEALEKERSSLHFQLPSQQPALSALLGHLGAQAQASLRWAAQRAGGDDPQARLRMDPKTLEAAAQDSLRVSITRRDWLLREKQQLQKEIETLQARMSVLEAKDQQLRREIEEQERLLPWQGCDLVGGLSLGELQEVTKTLQDTLALAEQIPLHAEPPETIRSLQERIKSLSLSLKEITAKVCMSERLCSALRKKVNDIETQLPALFEAKMLAISGNHFYTAKELTEEIRSLTLEREALEGLLHKLLVLSSRNVQKLGSVKEDYSRLRQELDQGRAAYETSVKVNTMKYMEMLEEKLHSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLFADERQTDDLGGGTYTMALATPLRSHLEDGRKNPLQAFEEWTVHLTPSPHCASSEQKEESYIFSAELGEKCETIGKKLLYLEDQLHVAIHSHDEDLIHILLILQMEHLLGYFVKESLKKLHSFPMPQQMETNRYSWYLEFNTPLISEIIQYVMFSL", "length": 862, "header": "tr|A0A3Q1MBR1-1|A0ABI0P0M3_BOVIN Computationally mapped isoform of DISC1 scaffold protein OS=Bos taurus OX=9913 GN=DISC1 PE=4 SV=1 CANONICAL=A0ABI0P0M3-1" }, "locus": { "chromosome": "28", "start_pos": 4868080, "end_pos": 4454907, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070721.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070721.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066138.1", "url": "https://www.ensembl.org/id/ENSBTAP00000066138.1" } ] } }, { "isoform_ac": "A0AAA9TD50-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3/entry#A0AAA9TD50-1", "sequence": { "sequence": "MLGGGPQGAPAGGGRGHRAAEMIQQRLEALEKERSSLHFQLPSQQPALSALLGHLGAQAQASLRWAAQRAGGDDPQARLRMDPKTLEAAAQDSLRVSITRRDWLLREKQQLQKEIETLQARMSVLEAKDQQLRREIEEQERLLPWQGCDLVGGLSLGELQEVTKTLQDTLALAEQIPLHAEPPETIRRKPFLYSQGAHRGDQIINTGEGSAGGTSSQAVGTEFQERPKAGKCERRLQQTQARTGPGESCL", "length": 250, "header": "tr|A0AAA9TD50-1|A0ABI0P0M3_BOVIN Computationally mapped isoform of DISC1 scaffold protein OS=Bos taurus OX=9913 GN=DISC1 PE=4 SV=1 CANONICAL=A0ABI0P0M3-1" }, "locus": { "chromosome": "28", "start_pos": 4665933, "end_pos": 4454907, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092548.1", "url": "https://www.ensembl.org/id/ENSBTAT00000092548.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094767.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094767.1" } ] } }, { "isoform_ac": "A0ABI0P0M3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3/entry#A0ABI0P0M3-1", "sequence": { "sequence": "MRSAAGPRIGFLSPPVGAPFRAQGGACGKESHHLESRAGPCGLDPGGQWRGRSVGSLIPRSTATSALTVGHRGPALTAAKGSPGLLGSQPRAGTALPNRLSRLCGPRATGCRGELPSTDTREAPSPCREAWNKGCPSPEDMSDTSCSLGSGPQAPAIPASSQDVFTSSFSFIRLSLGSAGERGEAEGCPPSREAEGPHQSLEEMEAKAASSGGPHDHPRLLSLPFTLKASQGLADATQTSGGSRGLECQTLPLLDTDAASSCSLDPLWFEASSSADAQRWDPLLSRCEPALLHCLQGQRRRLEVKSLRLKLQKLQDKAIEEDDYDKAEMIQQRLEALEKERSSLHFQLPSQQPALSALLGHLGAQAQASLRWAAQRAGGDDPQARLRMDPKTLEAAAQDSLRVSITRRDWLLREKQQLQKEIETLQARMSVLEAKDQQLRREIEEQERLLPWQGCDLVGGLSLGELQEVTKTLQDTLALAEQIPLHAEPPETIRSLQERIKSLSLSLKEITAKVCMSERLCSALRKKVNDIETQLPALFEAKMLAISGNHFYTAKELTEEIRSLTLEREALEGLLHKLLVLSSRNVQKLGSVKEDYSRLRQELDQGRAAYETSVKVNTMKYMEMLEEKLHSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLFADERQTDDLGGGTYTMALATPLRSHLEDGRKNPLQAFEEWTVHLTPSPHCASSEQKEESYIFSAELGEKCETIGKKLLYLEDQLHVAIHSHDEDLIHSLKGELQMVKETLQAMALQLQPAKEAGEREAAASCVTAGIREAQS", "length": 807, "header": "tr|A0ABI0P0M3-1|A0ABI0P0M3_BOVIN Isoform 1 of DISC1 scaffold protein OS=Bos taurus OX=9913 GN=DISC1 PE=4 SV=1 CANONICAL=A0ABI0P0M3-1" }, "locus": { "chromosome": "28", "start_pos": 4876417, "end_pos": 4538987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094997.2", "url": "https://www.ensembl.org/id/ENSBTAT00000094997.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104842.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104842.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:613555", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613555", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q810H6-1", "protein_name": "Disrupted in schizophrenia 1 homolog", "gene_name": "Disc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGAGSRGAWIHSPSHCPGNGHGSPPAVAPQRRRLTRRPGYMRSTASPGIGFLSPAVGMPRPISAGLTGQEFYPSQSKARQCSLDLRSHCQDSLVGNPFLKGSLGPAVTSVGHLHPAQGSMRERMVHSGVHSGNDRRQSERLTGDSGCRQEFLSSDSSKSLASSLDVAWSKGSRGLKTVRPLVSPASNGPVDIPSLPGFQDTFTSNFSFIRLSLGAAGERGEAEGCLPSREAEPLHQSPQEMAAEGSGSDRPHGEPRHLWTFSLHAAPGLVDLAQGTRSNRQPECGMVSSSDAGFSSQDASPAGGRSDQDGGWADAHGWHALLREWEPMLQDYLLSNRRQLEVTSLILKLQKLQEKAVEDGDYDMAETLRQRLEDLEQEKGRLPWALPSQQPALRSFLGYLATQTHAALHGAPQRAGSDDPEAPLEGQRRTTAQDSLPGLAVTRRDWLMREKEQLQKEIEALRARVSVLEAKEQRLSQELEDQEMLLRWQGCDQMALVAQLSPGQLQEVSKALGETLTSARWAPFRVEPPETLRSLRERTKSLDLAVRELTEQVCSGEKLCSSLRKRLADLDTRLPALLEAKMLALSGSCFSTAKELAEEIWAVSSEREGLEMFLGRLLALSSRNTRRLGSVKEDYLRCRQDLALQEAAHKTRVKANTVKCTEVLEGQLSCCRCPLLERVWKADLEACQLLMQSLEIQEAGSSSHVEDEKQVHSTGEAAQTAALAVPRTPHPEEEKSPLQVLCEWNTYSASLPHCAAGLWKEESHVVFAEVGDKCEAIGMRLLHLEDQLLGAMHGHDEALFQSLQGELQMVKETLQTMFLQLQPAKEAGGEASASYSTAGAQEAED", "length": 846 }, "evidence": [ { "id": "A0ABI0P0M3", "url": "https://omabrowser.org/oma/group/A0ABI0P0M3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NRI5-1", "protein_name": "Disrupted in schizophrenia 1 protein", "gene_name": "DISC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGGGPQGAPAAAGGGGVSHRAGSRDCLPPAACFRRRRLARRPGYMRSSTGPGIGFLSPAVGTLFRFPGGVSGEESHHSESRARQCGLDSRGLLVRSPVSKSAAAPTVTSVRGTSAHFGIQLRGGTRLPDRLSWPCGPGSAGWQQEFAAMDSSETLDASWEAACSDGARRVRAAGSLPSAELSSNSCSPGCGPEVPPTPPGSHSAFTSSFSFIRLSLGSAGERGEAEGCPPSREAESHCQSPQEMGAKAASLDGPHEDPRCLSRPFSLLATRVSADLAQAARNSSRPERDMHSLPDMDPGSSSSLDPSLAGCGGDGSSGSGDAHSWDTLLRKWEPVLRDCLLRNRRQMEVISLRLKLQKLQEDAVENDDYDKAETLQQRLEDLEQEKISLHFQLPSRQPALSSFLGHLAAQVQAALRRGATQQASGDDTHTPLRMEPRLLEPTAQDSLHVSITRRDWLLQEKQQLQKEIEALQARMFVLEAKDQQLRREIEEQEQQLQWQGCDLTPLVGQLSLGQLQEVSKALQDTLASAGQIPFHAEPPETIRSLQERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQLPALLEAKMHAISGNHFWTAKDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSVKENTMKYMETLKNKLCSCKCPLLGKVWEADLEACRLLIQSLQLQEARGSLSVEDERQMDDLEGAAPPIPPRLHSEDKRKTPLKVLEEWKTHLIPSLHCAGGEQKEESYILSAELGEKCEDIGKKLLYLEDQLHTAIHSHDEDLIQSLRRELQMVKETLQAMILQLQPAKEAGEREAAASCMTAGVHEAQA", "length": 854 }, "evidence": [ { "id": "A0ABI0P0M3", "url": "https://omabrowser.org/oma/group/A0ABI0P0M3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" }, { "name": "intermediate filament cytoskeleton", "id": "GO:0045111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045111", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" }, { "name": "positive regulation of neuroblast proliferation", "id": "GO:0002052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002052", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" }, { "name": "positive regulation of Wnt signaling pathway", "id": "GO:0030177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030177", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0M3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P3X9-1", "uniprot_ac": "A0ABI0P3X9", "uniprot_id": "A0ABI0P3X9_BOVIN", "mass": { "chemical_mass": 63717.0, "monoisotopic_mass": 63717.0 }, "refseq": { "ac": "XP_005203946", "name": "extracellular matrix protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005203946" }, "gene_names": [ { "name": "ECM1", "type": "recommended", "evidence": [ { "id": "A0ABI0P3X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3X9" } ] }, { "name": "ECM1", "type": "synonym", "evidence": [ { "id": "XP_005203946", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005203946" } ] } ], "protein_names": [ { "name": "Extracellular matrix protein 1", "type": "recommended", "evidence": [ { "id": "A0ABI0P3X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3X9/entry#names_and_taxonomy" } ] }, { "name": "Secretory component p85", "type": "synonym", "evidence": [ { "id": "A0ABI0P3X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3X9/entry#names_and_taxonomy" } ] }, { "name": "extracellular matrix protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005203946", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005203946" } ] } ], "function": [ { "annotation": "Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A3S5ZPB5", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPB5#function" }, { "database": "UniProtKB", "id": "ARBA00054936", "url": "https://www.uniprot.org/uniprotkb/ARBA00054936#function" }, { "database": "UniProtKB", "id": "A0ABI0P3X9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3X9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3X9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3X9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ECM1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3X9", "locus": { "chromosome": "3", "start_pos": 20184961, "end_pos": 20190366, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003806", "url": "https://www.ensembl.org/id/ENSBTAG00000003806" } ] } } ], "crossref": [ { "id": "ENSBTAG00000003806", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003806", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "524222", "url": "https://www.ncbi.nlm.nih.gov/gene/524222", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16776", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16776", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16776:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16776:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005203946", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005203946", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3S5ZPB5", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3S5ZPB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3X9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3X9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3X9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3X9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTMSGAALVLACLTVASVASDGGFKASGQRELGPQPLTHPLQQVGYAAPPSPPLSRALPQGHPRTSQHSLHSEGQSEVQPSPSQDAIPLQEELPAPQLPVEKKGGPPFPQEAIPLQEELPASQLPVEKKGGPPLPQEAIPLQEELPPPQVPIEQKEVSHSEEKPAPSMDHSPPEPESWNPAQHCQHGRPRGGWGHRLDGFPPGRPSLDNLDQICLPSRQHVVYGPWNLPQTGFSHLSRQGETLNLLETGYSRCCRCRNRTNRLDCAELVWEDSVTRFCEAEFSVKTQPHGCCKKQGEARLSCFQEEAPRPHYQLRACPSHQPGISLGPELPFPPGLPTVDNIKNICHLKRFRSVPRNLPATDSIQRQLQALTRLEAEFQRCCRQGNNHTCTWKAWEDTLDGYCDWEQAIKTHHHSCCNYPPSPLRDKCFARRAPYPNYDRDILTLDLSRITPNLMNHLCGNRRVLSKHKQIPGLIQKVTARCCDLPFPEQACCAEEEKSAFIDELCGSRRNFWRDSALCCKLSPGDEQINCFNTKYLRNVAVVTGDTRDAKGPGEQGPTQGTNSSPTSEPKEE", "length": 574, "header": "tr|A0ABI0P3X9-1|A0ABI0P3X9_BOVIN Isoform 1 of Extracellular matrix protein 1 OS=Bos taurus OX=9913 GN=ECM1 PE=4 SV=1 CANONICAL=A0ABI0P3X9-1" }, "isoforms": [ { "isoform_ac": "A0A3S5ZPB5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3X9/entry#A0A3S5ZPB5-1", "sequence": { "sequence": "MGTMSGAALVLACLTVASVASDGGFKASGQRELGPQPLTHPLQQVGYAAPPSPPLSRALPQGHPRTSQHSLHSEGQSEVQPSPSQDAIPLQEELPAPQLPVEKKEKPAPSMDHSPPEPESWNPAQHCQHGRPRGGWGHRLDGFPPGRPSLDNLDQICLPSRQHVVYGPWNLPQTGFSHLSRQGETLNLLETGYSRCCRCRNRTNRLDCAELVWEDSVTRFCEAEFSVKTQPHGCCKKQGEARLSCFQEEAPRPHYQLRACPSHQPGISLGPELPFPPGLPTVDNIKNICHLKRFRSVPRNLPATDSIQRQLQALTRLEAEFQRCCRQGNNHTCTWKAWEDTLDGYCDWEQAIKTHHHSCCNYPPSPLRDKCFARRAPYPNYDRDILTLDLSRITPNLMNHLCGNRRVLSKHKQIPGLIQKVTARCCDLPFPEQACCAEEEKSAFIDELCGSRRNFWRDSALCCKLSPGDEQINCFNTKYLRNVAVVTGDTRDAKGPGEQGPTQGTNSSPTSEPKEE", "length": 516, "header": "tr|A0A3S5ZPB5-1|A0ABI0P3X9_BOVIN Computationally mapped isoform of Extracellular matrix protein 1 OS=Bos taurus OX=9913 GN=ECM1 PE=4 SV=3 CANONICAL=A0ABI0P3X9-1" }, "locus": { "chromosome": "3", "start_pos": 20190270, "end_pos": 20185055, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004959.8", "url": "https://www.ensembl.org/id/ENSBTAT00000004959.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004959.8", "url": "https://www.ensembl.org/id/ENSBTAP00000004959.8" } ] } }, { "isoform_ac": "A0ABI0P3X9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3X9/entry#A0ABI0P3X9-1", "sequence": { "sequence": "MGTMSGAALVLACLTVASVASDGGFKASGQRELGPQPLTHPLQQVGYAAPPSPPLSRALPQGHPRTSQHSLHSEGQSEVQPSPSQDAIPLQEELPAPQLPVEKKGGPPFPQEAIPLQEELPASQLPVEKKGGPPLPQEAIPLQEELPPPQVPIEQKEVSHSEEKPAPSMDHSPPEPESWNPAQHCQHGRPRGGWGHRLDGFPPGRPSLDNLDQICLPSRQHVVYGPWNLPQTGFSHLSRQGETLNLLETGYSRCCRCRNRTNRLDCAELVWEDSVTRFCEAEFSVKTQPHGCCKKQGEARLSCFQEEAPRPHYQLRACPSHQPGISLGPELPFPPGLPTVDNIKNICHLKRFRSVPRNLPATDSIQRQLQALTRLEAEFQRCCRQGNNHTCTWKAWEDTLDGYCDWEQAIKTHHHSCCNYPPSPLRDKCFARRAPYPNYDRDILTLDLSRITPNLMNHLCGNRRVLSKHKQIPGLIQKVTARCCDLPFPEQACCAEEEKSAFIDELCGSRRNFWRDSALCCKLSPGDEQINCFNTKYLRNVAVVTGDTRDAKGPGEQGPTQGTNSSPTSEPKEE", "length": 574, "header": "tr|A0ABI0P3X9-1|A0ABI0P3X9_BOVIN Isoform 1 of Extracellular matrix protein 1 OS=Bos taurus OX=9913 GN=ECM1 PE=4 SV=1 CANONICAL=A0ABI0P3X9-1" }, "locus": { "chromosome": "3", "start_pos": 20190270, "end_pos": 20185055, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144871.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144871.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106056.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106056.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3X9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3X9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3X9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3X9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 259, "end_pos": 261 }, { "start_pos": 388, "end_pos": 390 }, { "start_pos": 564, "end_pos": 566 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P3K8-1", "uniprot_ac": "A0ABI0P3K8", "uniprot_id": "A0ABI0P3K8_BOVIN", "mass": { "chemical_mass": 49971.0, "monoisotopic_mass": 49971.0 }, "refseq": {}, "gene_names": [ { "name": "TUBB2B", "type": "recommended", "evidence": [ { "id": "A0ABI0P3K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8" } ] } ], "protein_names": [ { "name": "Tubulin beta chain", "type": "recommended", "evidence": [ { "id": "A0ABI0P3K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.", "evidence": [ { "database": "UniProtKB", "id": "G3N1W7", "url": "https://www.uniprot.org/uniprotkb/G3N1W7#function" }, { "database": "UniProtKB", "id": "RU000352", "url": "https://www.uniprot.org/uniprotkb/RU000352#function" }, { "database": "UniProtKB", "id": "A0A452DI48", "url": "https://www.uniprot.org/uniprotkb/A0A452DI48#function" }, { "database": "UniProtKB", "id": "A0ABI0P3K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TUBB2B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8", "locus": { "chromosome": "23", "start_pos": 50492430, "end_pos": 50489701, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000054330", "url": "https://www.ensembl.org/id/ENSBTAG00000054330" } ] } } ], "crossref": [ { "id": "ENSBTAG00000054330", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000054330", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02187", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02187", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013838", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013838", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017975", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017975", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11588", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11588", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03953", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03953", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A452DI48", "url": "https://www.uniprot.org/uniprotkb/A0A452DI48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DI48-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DI48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3K8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1W7", "url": "https://www.uniprot.org/uniprotkb/G3N1W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1W7-1", "url": "https://www.uniprot.org/uniprotkb/G3N1W7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEGHEDEEKDEGG", "length": 446, "header": "tr|A0ABI0P3K8-1|A0ABI0P3K8_BOVIN Isoform 1 of Tubulin beta chain OS=Bos taurus OX=9913 GN=TUBB2B PE=3 SV=1 CANONICAL=A0ABI0P3K8-1" }, "isoforms": [ { "isoform_ac": "A0A452DI48-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8/entry#A0A452DI48-1", "sequence": { "sequence": "MDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA", "length": 373, "header": "tr|A0A452DI48-1|A0ABI0P3K8_BOVIN Computationally mapped isoform of Tubulin beta chain OS=Bos taurus OX=9913 GN=TUBB2B PE=3 SV=1 CANONICAL=A0ABI0P3K8-1" }, "locus": { "chromosome": "11", "start_pos": 106257108, "end_pos": 106254900, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008372.4", "url": "https://www.ensembl.org/id/ENSBTAT00000008372.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008372.4", "url": "https://www.ensembl.org/id/ENSBTAP00000008372.4" } ] } }, { "isoform_ac": "A0ABI0P3K8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8/entry#A0ABI0P3K8-1", "sequence": { "sequence": "MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEGHEDEEKDEGG", "length": 446, "header": "tr|A0ABI0P3K8-1|A0ABI0P3K8_BOVIN Isoform 1 of Tubulin beta chain OS=Bos taurus OX=9913 GN=TUBB2B PE=3 SV=1 CANONICAL=A0ABI0P3K8-1" }, "locus": { "chromosome": "23", "start_pos": 50494254, "end_pos": 50489737, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136695.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136695.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105773.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105773.1" } ] } }, { "isoform_ac": "G3N1W7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8/entry#G3N1W7-1", "sequence": { "sequence": "MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQIYFAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA", "length": 330, "header": "tr|G3N1W7-1|A0ABI0P3K8_BOVIN Computationally mapped isoform of Tubulin beta chain OS=Bos taurus OX=9913 GN=TUBB2B PE=3 SV=1 CANONICAL=A0ABI0P3K8-1" }, "locus": { "chromosome": "23", "start_pos": 50492427, "end_pos": 50489737, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064631.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064631.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055871.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055871.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8" } ], "pmid": "" }, { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8" } ], "pmid": "" }, { "name": "microtubule-based process", "id": "GO:0007017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007017", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8" } ], "pmid": "" }, { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3K8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P3K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8" }, { "id": "SM00865", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubulin/FtsZ 2-layer sandwich", "eco_id": "ECO_0000259", "start_pos": 246, "end_pos": 383, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P3K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3K8" }, { "id": "SM00864", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00864" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubulin/FtsZ GTPase", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 244, "start_aa": "Ile", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 }, { "start_pos": 337, "end_pos": 339 }, { "start_pos": 370, "end_pos": 372 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P473-1", "uniprot_ac": "A0ABI0P473", "uniprot_id": "A0ABI0P473_BOVIN", "mass": { "chemical_mass": 49257.0, "monoisotopic_mass": 49257.0 }, "refseq": { "ac": "XP_005210990", "name": "MFS-type transporter SLC18B1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210990" }, "gene_names": [ { "name": "SLC18B1", "type": "recommended", "evidence": [ { "id": "A0ABI0P473", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473" } ] }, { "name": "SLC18B1", "type": "synonym", "evidence": [ { "id": "XP_005210990", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210990" } ] } ], "protein_names": [ { "name": "MFS-type transporter SLC18B1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_005210990", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210990" } ] }, { "name": "Solute carrier family 18 member B1", "type": "synonym", "evidence": [ { "id": "A0ABI0P473", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P473", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC18B1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473", "locus": { "chromosome": "9", "start_pos": 70927238, "end_pos": 70965960, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015242", "url": "https://www.ensembl.org/id/ENSBTAG00000015242" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015242", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015242", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17385", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17385", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "529052", "url": "https://www.ncbi.nlm.nih.gov/gene/529052", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:529052", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529052", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BHT6", "url": "https://www.orthodb.org/?gene=E1BHT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23506", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23506", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23506:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23506:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005210990", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210990", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MSH5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MSH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MSH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7X8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7X8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7X8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P473", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P473-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHT6", "url": "https://www.uniprot.org/uniprotkb/E1BHT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHT6-1", "url": "https://www.uniprot.org/uniprotkb/E1BHT6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSPGDPEGPRPQGGDGPPAGAMETSRRLSREQIFVLISAASINLGSMMCYSILGPFFPKEAEKKGASNTVIGTIFGCYALFDFLASLVFGKYLVHIGAKFMFVAGMFVSGAVTVLFGLLDQVPEGPVFIAMCFLLRITDAISFEAAITASSSIVAKAFPNNVATVLGSLETFSGLGLVLGPPLGGFLYQSFGYEVPFIFLGCIVLLMVPLNMCILPNYESDKGKHSFWKLITLPKVAFLSFVITSFSSCFGFLDPTLSLFVLEKFNLPAGYVGLVFLGLALSYAISSPLVGLLSDKMPHLRKWLLVFGNLTLAGCYMLLGPAPFLHIKSQLWLLVLILVINGISAGIGLIPTFPEILSCAHENGFEEGLSTLGLVSGLFGAMWSVGAFVGPTLGGFLYEKIGFEWAAALQGLWALTSGLAMGLFYLLEHLRRRRRSELQNILGTEEERTALLSDER", "length": 457, "header": "tr|A0ABI0P473-1|A0ABI0P473_BOVIN Isoform 1 of Solute carrier family 18 member B1 OS=Bos taurus OX=9913 GN=SLC18B1 PE=4 SV=1 CANONICAL=A0ABI0P473-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MSH5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473/entry#A0A3Q1MSH5-1", "sequence": { "sequence": "MDRGTWQATIQGVPKNWTQLGDGPPAGAMETSRRLSREQIFVLISAASINLGSMMCYSILGPFFPKEAEKKGASNTVIGTIFGCYALFDFLASLVFGKYLVHIGAKFMFVAGMFVSGAVTVLFGLLDQVPEGPVFIAMCFLLRITDAISFEAAITASSSIVAKAFPNNVATVLGSLETFSGLGLVLGPPLGGFLYQSFGYEVPFIFLGCIVLLMVPLNMCILPNYESDKGKHSFWKLITLPKVAFLSFVITSFSSCFGFLDPTLSLFVLEKFNLPAGYVGLVFLGLALSYAISSPLVGLLSDKMPHLRKWLLVFGNLTLAGCYMLLGPAPFLHIKSQLWLLVLILVINGISAGIGLIPTFPEILSCAHENGFEEGLSTLGLVSGLFGAMWSVGAFVGPTLGGFLYEKIGFEWAAALQGLWALTSGLAMGLFYLLEHLRRRRRSELQNILGTEEERTALLSDERGEG", "length": 466, "header": "tr|A0A3Q1MSH5-1|A0ABI0P473_BOVIN Computationally mapped isoform of Solute carrier family 18 member B1 OS=Bos taurus OX=9913 GN=SLC18B1 PE=4 SV=3 CANONICAL=A0ABI0P473-1" }, "locus": { "chromosome": "9", "start_pos": 70964230, "end_pos": 70928242, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085813.3", "url": "https://www.ensembl.org/id/ENSBTAT00000085813.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057455.3", "url": "https://www.ensembl.org/id/ENSBTAP00000057455.3" } ] } }, { "isoform_ac": "A0AAA9S7X8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473/entry#A0AAA9S7X8-1", "sequence": { "sequence": "MDRGTWQATIQGVPKNWTQLGDGPPAGAMETSRRLSREQIFVLISAASINLGSMMCYSILGPFFPKEAEKKGASNTVIGTIFGCYALFDFLASLVFGKYLVHIGAKFMFVAGMFVSGAVTVLFGLLDQVPEGPVFIAMCFLLRITDAISFEAAITASSSIVAKAFPNNVATVLGSLETFSGLGLVLGPPLGGFLYQSFGYEVPFIFLGCIVLLMVPLNMCILPNYESDKGKHSFWKLITLPKVAFLSFVITSFSSCFGFLDPTLSLFVLEKFNLPAGYVGLVFLGLALSYAISSPLVGLLSDKMPHLRKWLLVFGNLTLAGCYMLLGPAPFLHIKSENGFEEGLSTLGLVSGLFGAMWSVGAFVGPTLGGFLYEKIGFEWAAALQGLWALTSGLAMGLFYLLEHLRRRRRSELQNILGTEEERTALLSDER", "length": 431, "header": "tr|A0AAA9S7X8-1|A0ABI0P473_BOVIN Computationally mapped isoform of Solute carrier family 18 member B1 OS=Bos taurus OX=9913 GN=SLC18B1 PE=4 SV=1 CANONICAL=A0ABI0P473-1" }, "locus": { "chromosome": "9", "start_pos": 70964230, "end_pos": 70929918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102402.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102402.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079418.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079418.1" } ] } }, { "isoform_ac": "A0ABI0P473-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473/entry#A0ABI0P473-1", "sequence": { "sequence": "MDSPGDPEGPRPQGGDGPPAGAMETSRRLSREQIFVLISAASINLGSMMCYSILGPFFPKEAEKKGASNTVIGTIFGCYALFDFLASLVFGKYLVHIGAKFMFVAGMFVSGAVTVLFGLLDQVPEGPVFIAMCFLLRITDAISFEAAITASSSIVAKAFPNNVATVLGSLETFSGLGLVLGPPLGGFLYQSFGYEVPFIFLGCIVLLMVPLNMCILPNYESDKGKHSFWKLITLPKVAFLSFVITSFSSCFGFLDPTLSLFVLEKFNLPAGYVGLVFLGLALSYAISSPLVGLLSDKMPHLRKWLLVFGNLTLAGCYMLLGPAPFLHIKSQLWLLVLILVINGISAGIGLIPTFPEILSCAHENGFEEGLSTLGLVSGLFGAMWSVGAFVGPTLGGFLYEKIGFEWAAALQGLWALTSGLAMGLFYLLEHLRRRRRSELQNILGTEEERTALLSDER", "length": 457, "header": "tr|A0ABI0P473-1|A0ABI0P473_BOVIN Isoform 1 of Solute carrier family 18 member B1 OS=Bos taurus OX=9913 GN=SLC18B1 PE=4 SV=1 CANONICAL=A0ABI0P473-1" }, "locus": { "chromosome": "9", "start_pos": 70965392, "end_pos": 70929918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150770.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150770.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106517.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106517.1" } ] } }, { "isoform_ac": "E1BHT6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473/entry#E1BHT6-1", "sequence": { "sequence": "MDHTSPALQKENGQDVSICGQNRSWLLVDNRLSLKKKKKKSLLRPLSAPPPGATRCCPGDGPPAGAMETSRRLSREQIFVLISAASINLGSMMCYSILGPFFPKEAEKKGASNTVIGTIFGCYALFDFLASLVFGKYLVHIGAKFMFVAGMFVSGAVTVLFGLLDQVPEGPVFIAMCFLLRITDAISFEAAITASSSIVAKAFPNNVATVLGSLETFSGLGLVLGPPLGGFLYQSFGYEVPFIFLGCIVLLMVPLNMCILPNYESDKGKHSFWKLITLPKVAFLSFVITSFSSCFGFLDPTLSLFVLEKFNLPAGYVGLVFLGLALSYAISSPLVGLLSDKMPHLRKWLLVFGNLTLAGCYMLLGPAPFLHIKSQLWLLVLILVINGISAGIGLIPTFPEILSCAHENGFEEGLSTLGLVSGLFGAMWSVGAFVGPTLGGFLYEKIGFEWAAALQGLWALTSGLAMGLFYLLEHLRRRRRSELQNILGTEEERTALLSDER", "length": 501, "header": "tr|E1BHT6-1|A0ABI0P473_BOVIN Computationally mapped isoform of Solute carrier family 18 member B1 OS=Bos taurus OX=9913 GN=SLC18B1 PE=4 SV=3 CANONICAL=A0ABI0P473-1" }, "locus": { "chromosome": "9", "start_pos": 70965900, "end_pos": 70929918, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020271.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020271.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020271.7", "url": "https://www.ensembl.org/id/ENSBTAP00000020271.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 393, "start_aa": "Thr", "end_pos": 393, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr393", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:529052", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529052", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P473", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473" } ], "pmid": "" }, { "name": "monoamine:proton antiporter activity", "id": "GO:0015311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015311", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P473", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473" } ], "pmid": "" }, { "name": "polyamine:proton antiporter activity", "id": "GO:0015312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015312", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P473", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P473", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "spermine transport", "id": "GO:0000296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000296", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P473", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473" } ], "pmid": "" }, { "name": "serotonin uptake", "id": "GO:0051610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051610", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P473", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473" } ], "pmid": "" }, { "name": "spermidine transport", "id": "GO:0015848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015848", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P473", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P473", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P473" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 435, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 393 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 310, "end_pos": 312 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], 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{ "uniprot_canonical_ac": "A0ABI0P150-1", "uniprot_ac": "A0ABI0P150", "uniprot_id": "A0ABI0P150_BOVIN", "mass": { "chemical_mass": 19245.0, "monoisotopic_mass": 19245.0 }, "refseq": {}, "gene_names": [ { "name": "NIP7", "type": "recommended", "evidence": [ { "id": "A0ABI0P150", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150" } ] } ], "protein_names": [ { "name": "60S ribosome subunit biogenesis protein NIP7 homolog", "type": "recommended", "evidence": [ { "id": "A0ABI0P150", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P150", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150#function" }, { "database": "UniProtKB", "id": "PIRNR017190", "url": "https://www.uniprot.org/uniprotkb/PIRNR017190#function" }, { "database": "UniProtKB", "id": "ARBA00004087", "url": "https://www.uniprot.org/uniprotkb/ARBA00004087#function" }, { "database": "UniProtKB", "id": "A0ABI0P3Y0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Y0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P150", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NIP7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150", "locus": { "chromosome": "18", "start_pos": 36490885, "end_pos": 36481173, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001666", "url": "https://www.ensembl.org/id/ENSBTAG00000001666" } ] } } ], "crossref": [ { "id": "ENSBTAG00000001666", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001666", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21146", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21146", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21151", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21151", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016686", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016686", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BC14", "url": "https://www.orthodb.org/?gene=E1BC14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23415", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23415", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03657", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03657", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9T1Y1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TME3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TME3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TME3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TME3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P150", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P150-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3Y0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Y0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Y0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BC14", "url": "https://www.uniprot.org/uniprotkb/E1BC14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BC14-1", "url": "https://www.uniprot.org/uniprotkb/E1BC14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "EDSKIHRGESSAAGRQARRHLLFQAAQRPGVLREVRRRGASEKILKLAANISGDKLVSLGTCFGKFTKTHKFRLHITALDYLAPYAKYKVWIKPGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADVPLGFGVAAKSTQDCRKVDPMAIVVFHQADIGEYVRHEETLT", "length": 173, "header": "tr|A0ABI0P150-1|A0ABI0P150_BOVIN Isoform 1 of 60S ribosome subunit biogenesis protein NIP7 homolog OS=Bos taurus OX=9913 GN=NIP7 PE=3 SV=1 CANONICAL=A0ABI0P150-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T1Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150/entry#A0AAA9T1Y1-1", "sequence": { "sequence": "MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEKILKLAANISGDKLVSLGTCFGKFTKTHKFRLHITALDYLAPYAKGFGVAAKSTQDCRKVDPMAIVVFHQADIGEYVRHEETLT", "length": 133, "header": "tr|A0AAA9T1Y1-1|A0ABI0P150_BOVIN Computationally mapped isoform of 60S ribosome subunit biogenesis protein NIP7 homolog OS=Bos taurus OX=9913 GN=NIP7 PE=3 SV=1 CANONICAL=A0ABI0P150-1" }, "locus": { "chromosome": "18", "start_pos": 36482851, "end_pos": 36481198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115927.2", "url": "https://www.ensembl.org/id/ENSBTAT00000115927.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090418.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090418.1" } ] } }, { "isoform_ac": "A0AAA9TME3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150/entry#A0AAA9TME3-1", "sequence": { "sequence": "MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEKILKLAANISGDKLVSLGTCFGKFTKTHKFRLHITALDYLAPYAKYKVWIKPGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADVPLEEAPSLSHDFGHTATAPNLRNQAICFSDYSSIKFPFNCRPISLTAPTGGKRLTEHPLSSWRRDLPASYSHISLQRKYHYLLH", "length": 223, "header": "tr|A0AAA9TME3-1|A0ABI0P150_BOVIN Computationally mapped isoform of 60S ribosome subunit biogenesis protein NIP7 homolog OS=Bos taurus OX=9913 GN=NIP7 PE=3 SV=1 CANONICAL=A0ABI0P150-1" }, "locus": { "chromosome": "18", "start_pos": 36490608, "end_pos": 36481198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097583.2", "url": "https://www.ensembl.org/id/ENSBTAT00000097583.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099551.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099551.1" } ] } }, { "isoform_ac": "A0ABI0P150-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150/entry#A0ABI0P150-1", "sequence": { "sequence": "EDSKIHRGESSAAGRQARRHLLFQAAQRPGVLREVRRRGASEKILKLAANISGDKLVSLGTCFGKFTKTHKFRLHITALDYLAPYAKYKVWIKPGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADVPLGFGVAAKSTQDCRKVDPMAIVVFHQADIGEYVRHEETLT", "length": 173, "header": "tr|A0ABI0P150-1|A0ABI0P150_BOVIN Isoform 1 of 60S ribosome subunit biogenesis protein NIP7 homolog OS=Bos taurus OX=9913 GN=NIP7 PE=3 SV=1 CANONICAL=A0ABI0P150-1" }, "locus": { "chromosome": "18", "start_pos": 36482851, "end_pos": 36481239, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147780.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147780.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104620.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104620.1" } ] } }, { "isoform_ac": "A0ABI0P3Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150/entry#A0ABI0P3Y0-1", "sequence": { "sequence": "MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEKILKLAANISGDKLVSLGTCFGKFTKTHKFRLHITALDYLAPYAKYKVWIKPGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADVPLTLHNPQQPRHGMLLPQGPDKQSWERRHR", "length": 169, "header": "tr|A0ABI0P3Y0-1|A0ABI0P3Y0_BOVIN Computationally mapped isoform of 60S ribosome subunit biogenesis protein NIP7 homolog OS=Bos taurus OX=9913 GN=NIP7 PE=3 SV=1 CANONICAL=A0ABI0P150-1" }, "locus": { "chromosome": "18", "start_pos": 36513515, "end_pos": 36481198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150178.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150178.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105612.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105612.1" } ] } }, { "isoform_ac": "E1BC14-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150/entry#E1BC14-1", "sequence": { "sequence": "MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEKILKLAANISGDKLVSLGTCFGKFTKTHKFRLHITALDYLAPYAKYKVWIKPGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADVPLHPQGEKDLLNTHCLHGGEIYLHLILTSAYNGSTITYYIRNEMDIQGPGANSPSTSTAGALSRPHTPTPQDSVSVSL", "length": 217, "header": "tr|E1BC14-1|A0ABI0P150_BOVIN Computationally mapped isoform of 60S ribosome subunit biogenesis protein NIP7 homolog OS=Bos taurus OX=9913 GN=NIP7 PE=3 SV=3 CANONICAL=A0ABI0P150-1" }, "locus": { "chromosome": "18", "start_pos": 36490723, "end_pos": 36481198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002182.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002182.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002182.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002182.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P150", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P150", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P150", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P150", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P150", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150" } ], "pmid": "" }, { "name": "ribosome assembly", "id": "GO:0042255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042255", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P150", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P150", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P150" }, { "id": "SM00359", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00359" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PUA", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 163, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P0Z6-1", "uniprot_ac": "A0ABI0P0Z6", "uniprot_id": "A0ABI0P0Z6_BOVIN", "mass": { "chemical_mass": 109580.0, "monoisotopic_mass": 109580.0 }, "refseq": { "ac": "XP_015326900", "name": "zinc finger CCCH domain-containing protein 7B isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326900" }, "gene_names": [ { "name": "ZC3H7B", "type": "recommended", "evidence": [ { "id": "A0ABI0P0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Z6" } ] }, { "name": "ZC3H7B", "type": "synonym", "evidence": [ { "id": "XP_015326900", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326900" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH-type containing 7B", "type": "synonym", "evidence": [ { "id": "A0ABI0P0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Z6/entry#names_and_taxonomy" } ] }, { "name": "zinc finger CCCH domain-containing protein 7B isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015326900", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326900" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0Z6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Z6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZC3H7B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Z6", "locus": { "chromosome": "5", "start_pos": 112491986, "end_pos": 112455670, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002782", "url": "https://www.ensembl.org/id/ENSBTAG00000002782" } ] } } ], "crossref": [ { "id": "ENSBTAG00000002782", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002782", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "534109", "url": "https://www.ncbi.nlm.nih.gov/gene/534109", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BIU4", "url": "https://www.orthodb.org/?gene=E1BIU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14928", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14928", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14928:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14928:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015326900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326900", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0P0Z6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Z6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Z6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIU4", "url": "https://www.uniprot.org/uniprotkb/E1BIU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIU4-1", "url": "https://www.uniprot.org/uniprotkb/E1BIU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERQRRKADIEKGLQFIQSTLPLKQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGLNVADYAASDQVALPRELLCKLHVNRAACYFTMGLYEKALEDSEKALGLDSENIRALFRKARALTELGRHKEAYACSSRCSLALPHDESVTQLGQELAQKLGLRVRKAYKRPQELETFSLLSNGTAAGVADQGTSNGLGSIDDIETDCYVDLRGSPAPLPSTPTMPLFPHVLDLLAPLDSSSRALPGTESLDDFSDGDVFGPELDTLLDSLSLVQGGLPGGGVPSELPQLIPVFPGGTPLLPPVVGGSIPVSSPLPPASFGLVVDPSKKLAASVLDALEPPGSGLDSLDLLPYSETRLDALDSFGSSRGSLDKPSSFLEDTNSQDHRPSSGTQKPAPSPEPSMPNTALLIKNPLAATHEFKQACQLCYPKTGPRAGDYTYREGLEHKCKRDMLLGRLRSAEDQTWKRIRPRPTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGVKRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLVHIVRSTSLKYSKVRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYSGMTHEDIVQESKKYWQQMEAHTGKASSSLQGAPRTHGPSTFDLQMKFVCGQCWRNGQVVEPDKDLKYCSAKARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGRKCQYVGNCSFAHSPEERDMWTFMKENKILDMQQTYDMWLKKHNPGKPGEGTPVGSREGEKQIQMPTDYADIMMGYHCWLCGKNSNSKKQWQQHIQSEKHKEKVFTSDSDASGWAYRFPMGEFRLCDRLQKGKACPDGDKCRCAHGQEELNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGNAPGAALEAPATAAGTGD", "length": 977, "header": "tr|A0ABI0P0Z6-1|A0ABI0P0Z6_BOVIN Isoform 1 of Zinc finger CCCH-type containing 7B OS=Bos taurus OX=9913 GN=ZC3H7B PE=4 SV=1 CANONICAL=A0ABI0P0Z6-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P0Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Z6/entry#A0ABI0P0Z6-1", "sequence": { "sequence": 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Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2L8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L8#function" }, { "database": "UniProtKB", "id": "ARBA00029415", "url": "https://www.uniprot.org/uniprotkb/ARBA00029415#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2L8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UBA52", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L8", "locus": { "chromosome": "7", "start_pos": 4603746, "end_pos": 4606130, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007737", "url": "https://www.ensembl.org/id/ENSBTAG00000007737" } ] } } ], "crossref": [ { "id": "cd01803", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01803", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001975", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001975", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0P2L8", "url": 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Ubiquitin-ribosomal protein eL40 fusion protein OS=Bos taurus OX=9913 GN=UBA52 PE=3 SV=1 CANONICAL=A0ABI0P2L8-1" }, "locus": { "chromosome": "7", "start_pos": 4605176, "end_pos": 4603850, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141260.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141260.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107427.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107427.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2L8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": 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"total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2L8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P2L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L8" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 76, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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], "crossref": [ { "id": "132344649", "url": "https://www.ncbi.nlm.nih.gov/gene/132344649", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11875", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11875", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00956", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00956", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059740282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740282", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NIT8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NIT8", "database": 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"categories": [ "Protein Classification" ] }, { "id": "PF27089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NL56", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NL56-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NL56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRK2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRK2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1T1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1T1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1T1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1T1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKFTMGVRAPPRLLELASQSLLQNEALAIVALEELPTELFPPLFMAAFAGRHTQALKAMVQAWPFPCLPLGALMKDHQPHLETFQAVLDGLDILLGQEVRPRRWKLQVLDLRQNTHQDFWTLWSGIKASVCSLLVPEPAQPMQKRCKVEAQVVLKPAQAPVEVLVDLCLKEDTLDETISYLLKKAKQRRSLLHLRCQKLRIFTMPMQSIRRILKVVQLDSIQDLEVNCIWKLATLGRFVPHLGRMGNLRRLLLSRIHILPRTTPDQEEHFVDQLTIQFLNLPHLQKLYLDSISFLEGRLHQVLRCLKTPLETLWITNCLISESDLAYLSQCPSVSQLKDLGLSGVNLTSLSLEPLKVLIEWTSATLQDLDLDECGIMDSQFSALLPALSCCSQLTTFSFCGNPISMAVLESLLHHTMGLSKLSHVLYPSPLESYEDVRGTLHLGLLAQLHARLKRLLCESGRSSMVWVSASPCPHCGEQIFYDTEPILCPCYMPA", "length": 495, "header": "tr|A0ABI0P1T1-1|A0ABI0P1T1_BOVIN Isoform 1 of Melanoma antigen preferentially expressed in tumors OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P1T1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NL56-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1T1/entry#A0ABI0NL56-1", "sequence": { "sequence": "MGVRAPPRLLELASQSLLQNEALAIVALEELPTELFPPLFMAAFAGRHTQALKAMVQAWPFPCLPLGALMKDHQPHLETFQAVLDGLDILLGQEVRPRRWKLQVLDLRQNTHQDFWTLWSGIKASVCSLLVPEPAQPMQKRCKVEAQVVLKPAQAPVEVLVDLCLKEDTLDETISYLLKKAKQRRSLLHLRCQKLRIFTMPMQSIRRILKVVQLDSIQDLEVNCIWKLATLGRFVPHLGRMGNLRRLLLSRIHILPRTTPDQEEHFVDQLTIQFLNLPHLQKLYLDSISFLEGRLCLKTPLETLWITNCLISESDLAYLSQCPSVSQLKDLGLSGVNLTSLSLEPLKVLIEWTSATLQDLDLDECGIMDSQFSALLPALSCCSQLTTFSFCGNPISMAVLESLLHHTMGLSKLSHVLYPSPLESYEDVRGTLHLGLLAQLHARLKRLLCESGRSSMVWVSASPCPHCGDVNHWVSSVISDHDFPL", "length": 485, "header": "tr|A0ABI0NL56-1|A0ABI0P1T1_BOVIN Computationally mapped isoform of Melanoma antigen preferentially expressed in tumors OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P1T1-1" }, "locus": { "chromosome": "Y", "start_pos": 13742529, "end_pos": 13739214, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147402.1", "url": 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CANONICAL=A0ABI0P1T1-1" }, "locus": { "chromosome": "Y", "start_pos": 13742899, "end_pos": 13739214, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142418.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142418.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105277.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105277.1" } ] } }, { "isoform_ac": "A0ABI0P1T1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1T1/entry#A0ABI0P1T1-1", "sequence": { "sequence": "MKFTMGVRAPPRLLELASQSLLQNEALAIVALEELPTELFPPLFMAAFAGRHTQALKAMVQAWPFPCLPLGALMKDHQPHLETFQAVLDGLDILLGQEVRPRRWKLQVLDLRQNTHQDFWTLWSGIKASVCSLLVPEPAQPMQKRCKVEAQVVLKPAQAPVEVLVDLCLKEDTLDETISYLLKKAKQRRSLLHLRCQKLRIFTMPMQSIRRILKVVQLDSIQDLEVNCIWKLATLGRFVPHLGRMGNLRRLLLSRIHILPRTTPDQEEHFVDQLTIQFLNLPHLQKLYLDSISFLEGRLHQVLRCLKTPLETLWITNCLISESDLAYLSQCPSVSQLKDLGLSGVNLTSLSLEPLKVLIEWTSATLQDLDLDECGIMDSQFSALLPALSCCSQLTTFSFCGNPISMAVLESLLHHTMGLSKLSHVLYPSPLESYEDVRGTLHLGLLAQLHARLKRLLCESGRSSMVWVSASPCPHCGEQIFYDTEPILCPCYMPA", "length": 495, "header": "tr|A0ABI0P1T1-1|A0ABI0P1T1_BOVIN Isoform 1 of Melanoma antigen preferentially expressed in tumors OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P1T1-1" }, "locus": { "chromosome": "Y", "start_pos": 13742181, "end_pos": 13738790, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152544.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152544.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106997.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106997.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1T1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1T1" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1T1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1T1" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": 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} ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF13778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NLJ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NLJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NLJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWL2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NWL2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P050", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P050", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P050-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P050-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P205", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P205", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P205-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P205-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3M4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3M4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3M4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4I5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4I5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4I5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSPALRPALLLLLPLLLRVPPSRGFPGSGDSPLEDDEVVYSDAKYKDIPWCSPIKVKYGDVYCRAPQGGYYKTTLGTRCDIRCQKGYELQGSPQVICQSNKRWSDKVICKQKRCPTLAMPVNGGFKCIDGAYFNSQCEYYCSPGYTLKGEQTVRCMDNKAWSGQPATCVDLEPPRIKCPSVKERVAEPNKLTVRVSWETPEGRDTADGILTDVILKGPPPGSHFPEGDHKIQYTVYDRAENKGTCQFRVKVRVRRCGKLHAPENGYMKCSSDGDNYGAVCEFSCVGGYELQGSSARVCQSNLAWSGTEPTCTAMNVNVGVRTAAALLDQFYEKRRLFIVSTPTARNLLYRLQLGMLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKVMPPALALQLRCLMSSASIQKLFCGIYSVFKCSFDEFVGEKVVLPVLFLCHLRTASGKVFNFAVILFFQRLSLIL", "length": 463, "header": "tr|A0ABI0P205-1|A0ABI0P205_BOVIN Isoform 1 of Sushi repeat containing protein X-linked OS=Bos taurus OX=9913 GN=SRPX PE=4 SV=1 CANONICAL=A0ABI0P205-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NLJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P205/entry#A0ABI0NLJ2-1", "sequence": { "sequence": "MGSPALRPALLLLLPLLLRVPPSRGFPGSGDSPLEDDEVVYSDAKYKDIPWCSPIKVKYGDVYCRAPQGGYYKTTLGTRCDIRCQKGYELQGSPQVICQSNKRWSDKVICKQKRCPTLAMPVNGGFKCIDGAYFNSQCEYYCSPGYTLKGEQTVRCMDNKAWSGQPATCVDLEPPRIKCPSVKERVAEPNKLTVRVSWETPEGRDTADGILTDVILKGPPPGSHFPEGDHKIQYTVYDRAENKGTCQFRVKVRVRRCGKLHAPENGYMKCSSDGDNYGAVCEFSCVGGYELQGSSARVCQSNLAWSGTEPTCTAMNVNVGVRTAAALLDQFYEKRRLFIVSTPTARNLLYRLQLGMLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKVMPPALALQLRLLLRIPLYSFSIVVLDKHGVDKERYVSLVTPVALFNLIDTFPLRKEEMVLQAEMGQTCNT", "length": 459, "header": "tr|A0ABI0NLJ2-1|A0ABI0P205_BOVIN Computationally mapped isoform of Sushi repeat containing protein X-linked OS=Bos taurus OX=9913 GN=SRPX PE=4 SV=1 CANONICAL=A0ABI0P205-1" }, "locus": { "chromosome": "X", "start_pos": 105194006, "end_pos": 105052857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142222.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142222.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105948.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105948.1" } ] } }, { "isoform_ac": "A0ABI0NWL2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P205/entry#A0ABI0NWL2-1", "sequence": { "sequence": "MGSPALRPALLLLLPLLLRVPPSRGFPGSGDSPLEDDEVVYSDAKYKDIPWCSPIKVKYGDVYCRAPQGGYYKTTLGTRCDIRCQKGYELQGSPQVICQSNKRWSDKVICKHLEPPRIKCPSVKERVAEPNKLTVRVSWETPEGRDTADGILTDVILKGPPPGSHFPEGDHKIQYTVYDRAENKGTCQFRVKVRVRRCGKLHAPENGYMKCSSDGDNYGAVCEFSCVGGYELQGSSARVCQSNLAWSGTEPTCTAMNVNVGVRTAAALLDQFYEKRRLFIVSTPTARNLLYRLQLGMLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKVMPPALALQLRLLLRIPLYSFSIVVLDKHGVDKERYVSLVTPVALFNLIDTFPLRKEEMVLQAEMGQTCNT", "length": 400, "header": "tr|A0ABI0NWL2-1|A0ABI0P205_BOVIN Computationally mapped isoform of Sushi repeat containing protein X-linked OS=Bos taurus OX=9913 GN=SRPX PE=4 SV=1 CANONICAL=A0ABI0P205-1" }, "locus": { "chromosome": "X", "start_pos": 105194006, "end_pos": 105052857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147778.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147778.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104228.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104228.1" } ] } }, { "isoform_ac": "A0ABI0P050-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P205/entry#A0ABI0P050-1", "sequence": { "sequence": "MGSPALRPALLLLLPLLLRVPPSRGFPGSGDSPLEDDEVVYSDAKYKDIPWCSPIKVKYGDVYCRAPQGGYYKTTLGTRCDIRCQKGYELQGSPQVICQSNKRWSDKVICKQKRCPTLAMPVNGGFKCIDGAYFNSQCEYYCSPGYTLKGEQTVRCMDNKAWSGQPATCVDLEPPRIKCPSVKERVAEPNKLTVRVSWETPEGRDTADGILTDVILKGPPPGSHFPEGDHKIQYTVYDRAENKGTCQFRVKVRVRRCGKLHAPENGYMKCSSDGDNYGAVCEFSCVGGYELQGSSARVCQSNLAWSGTEPTCTAMNVNVGVRTAAALLDQFYEKRRLFIVSTPTARNLLYRLQLGMLQAVAANSTLFLQHRGTG", "length": 374, "header": "tr|A0ABI0P050-1|A0ABI0P205_BOVIN Computationally mapped isoform of Sushi repeat containing protein X-linked OS=Bos taurus OX=9913 GN=SRPX PE=4 SV=1 CANONICAL=A0ABI0P205-1" }, "locus": { "chromosome": "X", "start_pos": 105193873, "end_pos": 105052857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152195.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152195.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107047.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107047.1" } ] } }, { "isoform_ac": "A0ABI0P205-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P205/entry#A0ABI0P205-1", "sequence": { "sequence": "MGSPALRPALLLLLPLLLRVPPSRGFPGSGDSPLEDDEVVYSDAKYKDIPWCSPIKVKYGDVYCRAPQGGYYKTTLGTRCDIRCQKGYELQGSPQVICQSNKRWSDKVICKQKRCPTLAMPVNGGFKCIDGAYFNSQCEYYCSPGYTLKGEQTVRCMDNKAWSGQPATCVDLEPPRIKCPSVKERVAEPNKLTVRVSWETPEGRDTADGILTDVILKGPPPGSHFPEGDHKIQYTVYDRAENKGTCQFRVKVRVRRCGKLHAPENGYMKCSSDGDNYGAVCEFSCVGGYELQGSSARVCQSNLAWSGTEPTCTAMNVNVGVRTAAALLDQFYEKRRLFIVSTPTARNLLYRLQLGMLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKVMPPALALQLRCLMSSASIQKLFCGIYSVFKCSFDEFVGEKVVLPVLFLCHLRTASGKVFNFAVILFFQRLSLIL", "length": 463, "header": "tr|A0ABI0P205-1|A0ABI0P205_BOVIN Isoform 1 of Sushi repeat containing protein X-linked OS=Bos taurus OX=9913 GN=SRPX PE=4 SV=1 CANONICAL=A0ABI0P205-1" }, "locus": { "chromosome": "X", "start_pos": 105167077, "end_pos": 105052857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140393.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140393.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105052.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105052.1" } ] } }, { "isoform_ac": "A0ABI0P3M4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P205/entry#A0ABI0P3M4-1", "sequence": { "sequence": "MGSQILGSGDSPLEDDEVVYSDAKYKDIPWCSPIKVKYGDVYCRAPQGGYYKTTLGTRCDIRCQKGYELQGSPQVICQSNKRWSDKVICKQKRCPTLAMPVNGGFKCIDGAYFNSQCEYYCSPGYTLKGEQTVRCMDNKAWSGQPATCVDLEPPRIKCPSVKERVAEPNKLTVRVSWETPEGRDTADGILTDVILKGPPPGSHFPEGDHKIQYTVYDRAENKGTCQFRVKVRVRRCGKLHAPENGYMKCSSDGDNYGAVCEFSCVGGYELQGSSARVCQSNLAWSGTEPTCTAMNVNVGVRTAAALLDQFYEKRRLFIVSTPTARNLLYRLQLGMLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKVMPPALALQLRLLLRIPLYSFSIVVLDKHGVDKERYVSLVTPVALFNLIDTFPLRKEEMVLQAEMGQTCNT", "length": 438, "header": "tr|A0ABI0P3M4-1|A0ABI0P3M4_BOVIN Computationally mapped isoform of Sushi repeat containing protein X-linked OS=Bos taurus OX=9913 GN=SRPX PE=4 SV=1 CANONICAL=A0ABI0P205-1" }, "locus": { "chromosome": "X", "start_pos": 105194006, "end_pos": 105055437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144674.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144674.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106228.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106228.1" } ] } }, { "isoform_ac": "A0ABI0P4I5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P205/entry#A0ABI0P4I5-1", "sequence": { "sequence": "MGSPALRPALLLLLPLLLRVPPSRGFPDIPWCSPIKVKYGDVYCRAPQGGYYKTTLGTRCDIRCQKGYELQGSPQVICQSNKRWSDKVICKQKRCPTLAMPVNGGFKCIDGAYFNSQCEYYCSPGYTLKGEQTVRCMDNKAWSGQPATCVDLEPPRIKCPSVKERVAEPNKLTVRVSWETPEGRDTADGILTDVILKGPPPGSHFPEGDHKIQYTVYDRAENKGTCQFRVKVRVRRCGKLHAPENGYMKCSSDGDNYGAVCEFSCVGGYELQGSSARVCQSNLAWSGTEPTCTAMNVNVGVRTAAALLDQFYEKRRLFIVSTPTARNLLYRLQLGMLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKVMPPALALQLRLLLRIPLYSFSIVVLDKHGVDKERYVSLVTPVALFNLIDTFPLRKEEMVLQAEMGQTCNT", "length": 439, "header": "tr|A0ABI0P4I5-1|A0ABI0P4I5_BOVIN Computationally mapped isoform of Sushi repeat containing protein X-linked OS=Bos taurus OX=9913 GN=SRPX PE=4 SV=1 CANONICAL=A0ABI0P205-1" }, "locus": { "chromosome": "X", "start_pos": 105194006, "end_pos": 105052857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139938.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139938.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106478.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106478.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P205", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P205" }, { "id": "PS50825", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50825" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HYR", "eco_id": "ECO_0000259", "start_pos": 170, "end_pos": 254, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P205", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P205" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 112, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P505-1", "uniprot_ac": "A0ABI0P505", "uniprot_id": "A0ABI0P505_BOVIN", "mass": { "chemical_mass": 31204.0, "monoisotopic_mass": 31204.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM119", "type": "recommended", "evidence": [ { "id": "A0ABI0P505", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P505" } ] } ], "protein_names": [ { "name": "Transmembrane protein 119", "type": "synonym", "evidence": [ { "id": "A0ABI0P505", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P505/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P505", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P505" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM119", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P505", "locus": {} } ], "crossref": [ { "id": "510926", "url": "https://www.ncbi.nlm.nih.gov/gene/510926", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR28645", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28645", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28645:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28645:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15724", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15724", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NM31", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NM31-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P505", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P505", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P505-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P505-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGERVSTFTHQVPGNMVSAAAPSLAVSLLLLLRVLPTVSYSVSLQAGFLEDTGGSGEAEGSSASSPSLPPPQTPALSPTLVGPEPTPLAGPKPPTNFLDGIVDFFRQYVMLIAVVGSLVFLLMFIVCAAVITRQKHKASAYYPSSFPKKKYVDQSDRAGGPRAFSEVPDRAPDGRPEETLDSSQQLQAHILAATQNLKSPSRAAPSSGDLARAPEGRSEEEEKGPREADLEAQGRALPADKPEVPPLPEEPCSVEADAAAGAAAADEGQGEPDVAPLLAQEAGGPAGPPENPCVCGSVPPSI", "length": 302, "header": "tr|A0ABI0P505-1|A0ABI0P505_BOVIN Isoform 1 of Transmembrane protein 119 OS=Bos taurus OX=9913 GN=TMEM119 PE=4 SV=1 CANONICAL=A0ABI0P505-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NM31-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P505/entry#A0ABI0NM31-1", "sequence": { "sequence": "MVSAAAPSLAVSLLLLLRVLPTVSYSVSLQAGFLEDTGGSGEAEGSSASSPSLPPPQTPALSPTLVGPEPTPLAGPKPPTNFLDGIVDFFRQYVMLIAVVGSLVFLLMFIVCAAVITRQKHKASAYYPSSFPKKKYVDQSDRAGGPRAFSEVPDRAPDGRPEETLDSSQQLQAHILAATQNLKSPSRAAPSSGDLARAPEGRSEEEEKGPREADLEAQGRALPADKPEVPPLPEEPCSVEADAAAGAAAADEGQGEPDVAPLLAQEAGGPAGPPENPCVCGSVPPSI", "length": 287, "header": "tr|A0ABI0NM31-1|A0ABI0P505_BOVIN Computationally mapped isoform of Transmembrane protein 119 OS=Bos taurus OX=9913 GN=TMEM119 PE=4 SV=1 CANONICAL=A0ABI0P505-1" }, "locus": { "chromosome": "17", "start_pos": 64333004, "end_pos": 64332144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145282.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145282.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106375.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106375.1" } ] } }, { "isoform_ac": "A0ABI0P505-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P505/entry#A0ABI0P505-1", "sequence": { "sequence": "MGERVSTFTHQVPGNMVSAAAPSLAVSLLLLLRVLPTVSYSVSLQAGFLEDTGGSGEAEGSSASSPSLPPPQTPALSPTLVGPEPTPLAGPKPPTNFLDGIVDFFRQYVMLIAVVGSLVFLLMFIVCAAVITRQKHKASAYYPSSFPKKKYVDQSDRAGGPRAFSEVPDRAPDGRPEETLDSSQQLQAHILAATQNLKSPSRAAPSSGDLARAPEGRSEEEEKGPREADLEAQGRALPADKPEVPPLPEEPCSVEADAAAGAAAADEGQGEPDVAPLLAQEAGGPAGPPENPCVCGSVPPSI", "length": 302, "header": "tr|A0ABI0P505-1|A0ABI0P505_BOVIN Isoform 1 of Transmembrane protein 119 OS=Bos taurus OX=9913 GN=TMEM119 PE=4 SV=1 CANONICAL=A0ABI0P505-1" }, "locus": { "chromosome": "17", "start_pos": 64333004, "end_pos": 64329587, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154823.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154823.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106921.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106921.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 86, "start_aa": "Thr", "end_pos": 86, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr86", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P505", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P505" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 86 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P207-1", "uniprot_ac": "A0ABI0P207", "uniprot_id": "A0ABI0P207_BOVIN", "mass": { "chemical_mass": 97979.0, "monoisotopic_mass": 97979.0 }, "refseq": {}, "gene_names": [ { "name": "NLRP6", "type": "recommended", "evidence": [ { "id": "A0ABI0P207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P207" } ] } ], "protein_names": [ { "name": "NACHT, LRR and PYD domains-containing protein 6", "type": "recommended", "evidence": [ { "id": "A0ABI0P207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P207/entry#names_and_taxonomy" } ] }, { "name": "Angiotensin II/vasopressin receptor", "type": "synonym", "evidence": [ { "id": "A0ABI0P207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P207/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P207", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P207" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NLRP6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P207", "locus": {} } ], "crossref": [ { "id": "cd08321", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08321", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050637", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050637", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45690:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45690:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NMC9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMC9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P207", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P207", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P207-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P207-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AGQLEASCSSMEPRAAAARELLLGALEDLSQEQLKRFRHKLRDERVDGRSIPWGRLERADTLDLVEQLVHFYGPERALDVAKKTLKRADVRDVAARLKERRLQSLGPSSPALLSVSEYKKKYREHVLRQHAKVKERDARSVKINKRFTKLLIAEEPEAERARRSDTHTFNRLFGRDEEGERRLTVALQGPAGIGKTMAARKILYDWAAGKLYHSQVDFAFFLSCRELLERPGTCSLADLILDQCPDREAPVQQMLAQSERLLFILDGVDEMLAPEPAEAAPCRDPHEAASGARVLGSLLSKELLPAARLLVTRRGATPGRLQARLCSPQCAEVCGFSDKDRKKYFYKFFQDEWKAEHAYRSVKENEMLFSLCFVPGVCWIVCTVLRQQLQRGQDLWRTSKTTTAVYLLFVASVLRSAPAADAAQLQRELRKLCRLACDGVLGGRARFSEEDLERLQLCGSKVQTQFLSKKEMPGVLETEVTYQFIDQSFQEFLAALSYLLEDEGAPRAPAGSIEALLQGDPELRGHLNLTTRFLFGLLNTERMCEIKRHFGCTVSERVKQRVLRWVQDQGQGRPRAAPEGTEEILAPQDTEESEEEEGEQLNYPLELLYCLHETQEDAFVHQALRGLPELVLERVHFSRMDLAVLSYCVRCCPAGQALRLVSCRLATAQEKKKKSLMKRLQGSLGGSSSRATTRKSPGSPLRPLCEAMTDRQCGLNSLTLSRCKLPDSVCRDLSEALREAPALAELGLFHNGLSEAGLRVLSEGLASPQCRVQTLRVQQPGLQEALQYMVGKLQQIPALTTLDLSGCQLSGPTVTCLCTTLKCPGCHLQTLRLTSVELSEQALQELQAVETANPRLVITHPALDAHPKPPTVPISAL", "length": 877, "header": "tr|A0ABI0P207-1|A0ABI0P207_BOVIN Isoform 1 of NACHT, LRR and PYD domains-containing protein 6 OS=Bos taurus OX=9913 GN=NLRP6 PE=3 SV=1 CANONICAL=A0ABI0P207-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NMC9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P207/entry#A0ABI0NMC9-1", "sequence": { "sequence": "MEPRAAAARELLLGALEDLSQEQLKRFRHKLRDERVDGRSIPWGRLERADTLDLVEQLVHFYGPERALDVAKKTLKRADVRDVAARLKERRLQSLGPSSPALLSVSEYKKKYREHVLRQHAKVKERDARSVKINKRFTKLLIAEEPEAERARRSDTHTFNRLFGRDEEGERRLTVALQGPAGIGKTMAARKILYDWAAGKLYHSQVDFAFFLSCRELLERPGTCSLADLILDQCPDREAPVQQMLAQSERLLFILDGVDEMLAPEPAEAAPCRDPHEAASGARVLGSLLSKELLPAARLLVTRRGATPGRLQARLCSPQCAEVCGFSDKDRKKYFYKFFQDEWKAEHAYRSVKENEMLFSLCFVPGVCWIVCTVLRQQLQRGQDLWRTSKTTTAVYLLFVASVLRSAPAADAAQLQRELRKLCRLACDGVLGGRARFSEEDLERLQLCGSKVQTQFLSKKEMPGVLETEVTYQFIDQSFQEFLAALSYLLEDEGAPRAPAGSIEALLQGDPELRGHLNLTTRFLFGLLNTERMCEIKRHFGCTVSERVKQRVLRWVQDQGQGRPRAAPEGTEEILAPQDTEESEEEEGEQLNYPLELLYCLHETQEDAFVHQALRGLPELVLERVHFSRMDLAVLSYCVRCCPAGQALRLVSCRLATAQEKKKKSLMKRLQGSLGGSSSRATTRKSPGSPLRPLCEAMTDRQCGLNSLTLSRCKLPDSVCRDLSEALREAPALAELGLFHNGLSEAGLRVLSEGLASPQCRVQTLRVQQPGLQEALQYMVGKLQQIPALTTLDLSGCQLSGPTVTCLCTTLKCPGCHLQTLRWRQGWEGCWEHSLSALGWGGCRGFPQTLKRNLSQGPPEVTPL", "length": 864, "header": "tr|A0ABI0NMC9-1|A0ABI0P207_BOVIN Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 6 OS=Bos taurus OX=9913 GN=NLRP6 PE=3 SV=1 CANONICAL=A0ABI0P207-1" }, "locus": { "chromosome": "11", "start_pos": 82953771, "end_pos": 82948817, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152787.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152787.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106581.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106581.1" } ] } }, { "isoform_ac": "A0ABI0P207-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P207/entry#A0ABI0P207-1", "sequence": { "sequence": "AGQLEASCSSMEPRAAAARELLLGALEDLSQEQLKRFRHKLRDERVDGRSIPWGRLERADTLDLVEQLVHFYGPERALDVAKKTLKRADVRDVAARLKERRLQSLGPSSPALLSVSEYKKKYREHVLRQHAKVKERDARSVKINKRFTKLLIAEEPEAERARRSDTHTFNRLFGRDEEGERRLTVALQGPAGIGKTMAARKILYDWAAGKLYHSQVDFAFFLSCRELLERPGTCSLADLILDQCPDREAPVQQMLAQSERLLFILDGVDEMLAPEPAEAAPCRDPHEAASGARVLGSLLSKELLPAARLLVTRRGATPGRLQARLCSPQCAEVCGFSDKDRKKYFYKFFQDEWKAEHAYRSVKENEMLFSLCFVPGVCWIVCTVLRQQLQRGQDLWRTSKTTTAVYLLFVASVLRSAPAADAAQLQRELRKLCRLACDGVLGGRARFSEEDLERLQLCGSKVQTQFLSKKEMPGVLETEVTYQFIDQSFQEFLAALSYLLEDEGAPRAPAGSIEALLQGDPELRGHLNLTTRFLFGLLNTERMCEIKRHFGCTVSERVKQRVLRWVQDQGQGRPRAAPEGTEEILAPQDTEESEEEEGEQLNYPLELLYCLHETQEDAFVHQALRGLPELVLERVHFSRMDLAVLSYCVRCCPAGQALRLVSCRLATAQEKKKKSLMKRLQGSLGGSSSRATTRKSPGSPLRPLCEAMTDRQCGLNSLTLSRCKLPDSVCRDLSEALREAPALAELGLFHNGLSEAGLRVLSEGLASPQCRVQTLRVQQPGLQEALQYMVGKLQQIPALTTLDLSGCQLSGPTVTCLCTTLKCPGCHLQTLRLTSVELSEQALQELQAVETANPRLVITHPALDAHPKPPTVPISAL", "length": 877, "header": "tr|A0ABI0P207-1|A0ABI0P207_BOVIN Isoform 1 of NACHT, LRR and PYD domains-containing protein 6 OS=Bos taurus OX=9913 GN=NLRP6 PE=3 SV=1 CANONICAL=A0ABI0P207-1" }, "locus": { "chromosome": "11", "start_pos": 82954241, "end_pos": 82948060, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150915.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150915.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106782.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106782.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 317, "start_aa": "Thr", "end_pos": 317, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr317", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], 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"Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 183, "end_pos": 387, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P207" }, { "id": "PS50824", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50824" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pyrin", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 103, "start_aa": "Met", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 317 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 528, "end_pos": 530 } ] }, "class_list": [], "section_stats": [ { 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"A0ABI0P1J5_BOVIN", "mass": { "chemical_mass": 25293.0, "monoisotopic_mass": 25293.0 }, "refseq": {}, "gene_names": [ { "name": "MCRIP2", "type": "recommended", "evidence": [ { "id": "A0ABI0P1J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J5" } ] } ], "protein_names": [ { "name": "MAPK regulated corepressor interacting protein 2", "type": "synonym", "evidence": [ { "id": "A0ABI0P1J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1J5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MCRIP2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J5", "locus": {} } ], "crossref": [ { "id": "618020", "url": "https://www.ncbi.nlm.nih.gov/gene/618020", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF14799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NNZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P139", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P139", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P139-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P139-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1J5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1J5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3R9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3R9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5C2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5C2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5C2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6E2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6E2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRGLAGYSPWGHKELDMTERLTHRREGLPQQLSGPTQQQVESRLGELLKCRHSAPTPQHPRAQPPGPWPLSRMLLFILVPLSTEEEPRAAVGHLSPGWRAGRRDRECLAEWHVQPRTPGSHLLLPGPRLVFNRVNGRRPPATSPSLEGTQEPYTLAHEENVRFVSEAWQQVEQQLGGGPAGESGPRPVQYVERTPNPRLQNFVPIDLDEWWAQQFLARITSCS", "length": 224, "header": "tr|A0ABI0P1J5-1|A0ABI0P1J5_BOVIN Isoform 1 of MAPK regulated corepressor interacting protein 2 OS=Bos taurus OX=9913 GN=MCRIP2 PE=3 SV=1 CANONICAL=A0ABI0P1J5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NNZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J5/entry#A0ABI0NNZ3-1", "sequence": { "sequence": "MRFLADWIRTDAGETIATAAFRKLMLLFILVPLSTEEEPRAAVGHLSPGWRAGRRDRECLAEWHVQPRTPGSHLLLPGPRLVFNRVNGRRPPATSPSLEGTQEPYTLAHEENVRFVSEAWQQVEQQLGGGPAGESGPRPVQYVERTPNPRLQNFVPIDLDEWWAQQFLARITSCS", "length": 175, "header": "tr|A0ABI0NNZ3-1|A0ABI0P1J5_BOVIN Computationally mapped isoform of MAPK regulated corepressor interacting protein 2 OS=Bos taurus OX=9913 GN=MCRIP2 PE=3 SV=1 CANONICAL=A0ABI0P1J5-1" }, "locus": { "chromosome": "25", "start_pos": 557730, "end_pos": 546484, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153439.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153439.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107527.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107527.1" } ] } }, { "isoform_ac": "A0ABI0P139-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J5/entry#A0ABI0P139-1", "sequence": { "sequence": "MQACRRKASATGCSPQLPCGSGKCLEWAWPVGRGGLRLLRELCQVAPGLGMWLSVSLPSHSPGPRLVFNRVNGRRPPATSPSLEGTQEPYTLAHEENVRFVSEAWQQVEQQLGGGPAGESGPRPVQYVERTPNPRLQSEPSPTLKERPLPSTPDLAQPGSSPKGVG", "length": 166, "header": "tr|A0ABI0P139-1|A0ABI0P139_BOVIN Computationally mapped isoform of MAPK regulated corepressor interacting protein 2 OS=Bos taurus OX=9913 GN=MCRIP2 PE=3 SV=1 CANONICAL=A0ABI0P1J5-1" }, "locus": { "chromosome": "25", "start_pos": 557533, "end_pos": 556805, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143988.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143988.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104857.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104857.1" } ] } }, { "isoform_ac": "A0ABI0P1J5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J5/entry#A0ABI0P1J5-1", "sequence": { "sequence": "MDRGLAGYSPWGHKELDMTERLTHRREGLPQQLSGPTQQQVESRLGELLKCRHSAPTPQHPRAQPPGPWPLSRMLLFILVPLSTEEEPRAAVGHLSPGWRAGRRDRECLAEWHVQPRTPGSHLLLPGPRLVFNRVNGRRPPATSPSLEGTQEPYTLAHEENVRFVSEAWQQVEQQLGGGPAGESGPRPVQYVERTPNPRLQNFVPIDLDEWWAQQFLARITSCS", "length": 224, "header": "tr|A0ABI0P1J5-1|A0ABI0P1J5_BOVIN Isoform 1 of MAPK regulated corepressor interacting protein 2 OS=Bos taurus OX=9913 GN=MCRIP2 PE=3 SV=1 CANONICAL=A0ABI0P1J5-1" }, "locus": { "chromosome": "25", "start_pos": 557730, "end_pos": 550630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150025.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150025.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104393.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104393.1" } ] } }, { "isoform_ac": "A0ABI0P3R9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J5/entry#A0ABI0P3R9-1", "sequence": { "sequence": "MYTITKGPSKLVAQRRTGPTQQQVESRLGELLKCRHSAPTPQHPRAQPPGPWPLSRMLLFILVPLSTEEEPRAAVGHLSPGWRAGRRDRECLAEWHVQPRTPGSHLLLPGPRLVFNRVNGRRPPATSPSLEGTQEPYTLAHEENVRFVSEAWQQVEQQLGGGPAGESGPRPVQYVERTPNPRLQNFVPIDLDEWWAQQFLARITSCS", "length": 207, "header": "tr|A0ABI0P3R9-1|A0ABI0P3R9_BOVIN Computationally mapped isoform of MAPK regulated corepressor interacting protein 2 OS=Bos taurus OX=9913 GN=MCRIP2 PE=3 SV=1 CANONICAL=A0ABI0P1J5-1" }, "locus": { "chromosome": "25", "start_pos": 557730, "end_pos": 553054, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149252.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149252.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105851.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105851.1" } ] } }, { "isoform_ac": "A0ABI0P5C2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J5/entry#A0ABI0P5C2-1", "sequence": { "sequence": "MDRGLAGYSPWGHKELDMTERLTHRREGLPQQLSGPTQQQVESRLGELLKCRHSAPTPQHPRAQPPGPWPLSSPGPRLVFNRVNGRRPPATSPSLEGTQEPYTLAHEENVRFVSEAWQQVEQQLGGGPAGESGPRPVQYVERTPNPRLQNFVPIDLDEWWAQQFLARITSCS", "length": 172, "header": "tr|A0ABI0P5C2-1|A0ABI0P5C2_BOVIN Computationally mapped isoform of MAPK regulated corepressor interacting protein 2 OS=Bos taurus OX=9913 GN=MCRIP2 PE=3 SV=1 CANONICAL=A0ABI0P1J5-1" }, "locus": { "chromosome": "25", "start_pos": 557730, "end_pos": 550630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146640.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146640.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106910.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106910.1" } ] } }, { "isoform_ac": "A0ABI0P6E2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J5/entry#A0ABI0P6E2-1", "sequence": { "sequence": "MLLFILVPLSTEEEPRAAVGHLSPGWRAGRRDRECLAEWHVQPRTPGSHLLLPGPRLVFNRVNGRRPPATSPSLEGTQEPYTLAHEENVRFVSEAWQQVEQQLGGGPAGESGPRPVQYVERTPNPRLQNFVPIDLDEWWAQQFLARITSCS", "length": 151, "header": "tr|A0ABI0P6E2-1|A0ABI0P6E2_BOVIN Computationally mapped isoform of MAPK regulated corepressor interacting protein 2 OS=Bos taurus OX=9913 GN=MCRIP2 PE=3 SV=1 CANONICAL=A0ABI0P1J5-1" }, "locus": { "chromosome": "25", "start_pos": 557730, "end_pos": 555963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146210.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146210.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107191.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107191.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1J5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J5" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1J5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1J5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P0H9-1", "uniprot_ac": "A0ABI0P0H9", "uniprot_id": "A0ABI0P0H9_BOVIN", "mass": { "chemical_mass": 76752.0, "monoisotopic_mass": 76752.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF317", "type": "recommended", "evidence": [ { "id": "A0ABI0P0H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H9" } ] } ], "protein_names": [ { "name": "Zinc finger protein 317", "type": "recommended", "evidence": [ { "id": "A0ABI0P0H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0H9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF317", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H9", "locus": {} } ], "crossref": [ { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376:SF189", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376:SF189", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF218", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF218", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NQR0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQR0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0H9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0H9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3Y5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MREKVASWSKALFFRQIYCHSRKMAALGLAPTCAMPSQEPAYIHESEVPLSSKDHSCPQDVDLFACNGLEPHTSTSVEPSQESVTFQDVAVDFTEKEWPLLDSTQRKLYKDVMLENYSNLASVGCQVGKPSLISHLEQEEELRTEDRELHRGPCPDWAMPSKTKWSILMEDIFGKETSNGVTVENSQLGEESAEYTNLFDVFSIGAHLTQQMGRHTGKRPYHHRDCGVTFRNRSHVTQHVSIYNGRKMHECHQCQKAFTTSASLTRHRRIHTGEKPYECNACGKAFNDPSALRSHSRTHLTEKPFDCTQCGNAFRTLSSLKIHMRVHTGERPYKCDECGKAYGRSCHLIAHRRTHTGERPYECHDCGKAFQHPSHLKEHVRNHTGEKPYECTQCGKAFRWKSNFNLHKKNHTVEKTYECKECGKSFGDLLSRRKHMRIHIVKKPVECRQCGKAFRNQSILKTHMNSHTGEKPYGCDLCGKAFSASSNLTAHRKIHTQERRYECAACGKVFGDYLSRRRHMSIHLVKKRVECRQCGKAFRNQSTLKTHMRSHTGEKPYECDHCGKAFSIGSNLNVHRRIHTGEKPYECLACGKAFSDHSSLRSHVKTHRVAISLYLSLRPLLEKNAAVQTFLESRILPIGVPLLVQDGGINKHVHKYGSHCFLQMCAFDVNFL", "length": 672, "header": "tr|A0ABI0P0H9-1|A0ABI0P0H9_BOVIN Isoform 1 of Zinc finger protein 317 OS=Bos taurus OX=9913 GN=ZNF317 PE=3 SV=1 CANONICAL=A0ABI0P0H9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NQR0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H9/entry#A0ABI0NQR0-1", "sequence": { "sequence": "MGRGVVHRSFLQALGPRGRSDFPYELVIPSAAASVTFASHDSTVGDESVTFQDVAVDFTEKEWPLLDSTQRKLYKDVMLENYSNLASVGCQVGKPSLISHLEQEEELRTEDRELHRGPCPDWAMPSKTKWSILMEDIFGKETSNGVTVENSQLGEESAEYTNLFDVFSIGAHLTQQMGRHTGKRPYHHRDCGVTFRNRSHVTQHVSIYNGRKMHECHQCQKAFTTSASLTRHRRIHTGEKPYECNACGKAFNDPSALRSHSRTHLTEKPFDCTQCGNAFRTLSSLKIHMRVHTGERPYKCDECGKAYGRSCHLIAHRRTHTGERPYECHDCGKAFQHPSHLKEHVRNHTGEKPYECTQCGKAFRWKSNFNLHKKNHTVEKTYECKECGKSFGDLLSRRKHMRIHIVKKPVECRQCGKAFRNQSILKTHMNSHTGEKPYGCDLCGKAFSASSNLTAHRKIHTQERRYECAACGKVFGDYLSRRRHMSIHLVKKRVECRQCGKAFRNQSTLKTHMRSHTGEKPYECDHCGKAFSIGSNLNVHRRIHTGEKPYECLACGKAFSDHSSLRSHVKTHRGEKLFVSSVWKRLQ", "length": 587, "header": "tr|A0ABI0NQR0-1|A0ABI0P0H9_BOVIN Computationally mapped isoform of Zinc finger protein 317 OS=Bos taurus OX=9913 GN=ZNF317 PE=3 SV=1 CANONICAL=A0ABI0P0H9-1" }, "locus": { "chromosome": "7", "start_pos": 13621927, "end_pos": 13609777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142549.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142549.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105776.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105776.1" } ] } }, { "isoform_ac": "A0ABI0P0H9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H9/entry#A0ABI0P0H9-1", "sequence": { "sequence": "MREKVASWSKALFFRQIYCHSRKMAALGLAPTCAMPSQEPAYIHESEVPLSSKDHSCPQDVDLFACNGLEPHTSTSVEPSQESVTFQDVAVDFTEKEWPLLDSTQRKLYKDVMLENYSNLASVGCQVGKPSLISHLEQEEELRTEDRELHRGPCPDWAMPSKTKWSILMEDIFGKETSNGVTVENSQLGEESAEYTNLFDVFSIGAHLTQQMGRHTGKRPYHHRDCGVTFRNRSHVTQHVSIYNGRKMHECHQCQKAFTTSASLTRHRRIHTGEKPYECNACGKAFNDPSALRSHSRTHLTEKPFDCTQCGNAFRTLSSLKIHMRVHTGERPYKCDECGKAYGRSCHLIAHRRTHTGERPYECHDCGKAFQHPSHLKEHVRNHTGEKPYECTQCGKAFRWKSNFNLHKKNHTVEKTYECKECGKSFGDLLSRRKHMRIHIVKKPVECRQCGKAFRNQSILKTHMNSHTGEKPYGCDLCGKAFSASSNLTAHRKIHTQERRYECAACGKVFGDYLSRRRHMSIHLVKKRVECRQCGKAFRNQSTLKTHMRSHTGEKPYECDHCGKAFSIGSNLNVHRRIHTGEKPYECLACGKAFSDHSSLRSHVKTHRVAISLYLSLRPLLEKNAAVQTFLESRILPIGVPLLVQDGGINKHVHKYGSHCFLQMCAFDVNFL", "length": 672, "header": "tr|A0ABI0P0H9-1|A0ABI0P0H9_BOVIN Isoform 1 of Zinc finger protein 317 OS=Bos taurus OX=9913 GN=ZNF317 PE=3 SV=1 CANONICAL=A0ABI0P0H9-1" }, "locus": { "chromosome": "7", "start_pos": 13633628, "end_pos": 13617570, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144912.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144912.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103993.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103993.1" } ] } }, { "isoform_ac": "A0ABI0P3Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H9/entry#A0ABI0P3Y5-1", "sequence": { "sequence": "MREKVASWSKALFFRQIYCHSRKMAALGLAPTCAMPSQEPAYIHESEVPLSSKDHSCPQDVDLFACNGLEPHTSTSVEPSQESVTFQDVAVDFTEKEWPLLDSTQRKLYKDVMLENYSNLASVVGCQVGKPSLISHLEQEEELRTEDRELHRGPCPDWAMPSKTKWSILMEDIFGKETSNGVTVENSQLGEESAEYTNLFDVFSIGAHLTQQMGRHTGKRPYHHRDCGVTFRNRSHVTQHVSIYNGRKMHECHQCQKAFTTSASLTRHRRIHTGEKPYECNACGKAFNDPSALRSHSRTHLTEKPFDCTQCGNAFRTLSSLKIHMRVHTGERPYKCDECGKAYGRSCHLIAHRRTHTGERPYECHDCGKAFQHPSHLKEHVRNHTGEKPYECTQCGKAFRWKSNFNLHKKNHTVEKTYECKECGKSFGDLLSRRKHMRIHIVKKPVECRQCGKAFRNQSILKTHMNSHTGEKPYGCDLCGKAFSASSNLTAHRKIHTQERRYECAACGKVFGDYLSRRRHMSIHLVKKRVECRQCGKAFRNQSTLKTHMRSHTGEKPYECDHCGKAFSIGSNLNVHRRIHTGEKPYECLACGKAFSDHSSLRSHVKTHRGEKLFVSSVWKRLQ", "length": 623, "header": "tr|A0ABI0P3Y5-1|A0ABI0P3Y5_BOVIN Computationally mapped isoform of Zinc finger protein 317 OS=Bos taurus OX=9913 GN=ZNF317 PE=3 SV=1 CANONICAL=A0ABI0P0H9-1" }, "locus": { "chromosome": "7", "start_pos": 13621927, "end_pos": 13617570, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139721.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139721.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107747.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107747.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0H9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0H9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0H9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 487, "end_pos": 489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P0H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H9" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 249, "end_pos": 276, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P0H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H9" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 155, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 382, "end_pos": 384 }, { "start_pos": 410, "end_pos": 412 }, { "start_pos": 456, "end_pos": 458 }, { "start_pos": 487, "end_pos": 489 }, { "start_pos": 540, "end_pos": 542 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P2E4-1", "uniprot_ac": "A0ABI0P2E4", "uniprot_id": "A0ABI0P2E4_BOVIN", "mass": { "chemical_mass": 35430.0, "monoisotopic_mass": 35430.0 }, "refseq": {}, "gene_names": [ { "name": "PNPLA4", "type": "recommended", "evidence": [ { "id": "A0ABI0P2E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4" } ] } ], "protein_names": [ { "name": "Patatin like phospholipase domain containing 4", "type": "synonym", "evidence": [ { "id": "A0ABI0P2E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2E4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PNPLA4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4", "locus": { "chromosome": "X", "start_pos": 134951233, "end_pos": 134903796, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015849", "url": "https://www.ensembl.org/id/ENSBTAG00000015849" } ] } } ], "crossref": [ { "id": "cd07222", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07222", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "785567", "url": "https://www.ncbi.nlm.nih.gov/gene/785567", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12406", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12406", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12406:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12406:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01734", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01734", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NRM8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRM8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NU21", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NU21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NU21-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NU21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NU97", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NU97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NU97-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NU97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYE6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYE6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2E4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2E4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLCAEVSQTCVGDPLNPGIKPRSPALQTDSLPAESQGKPKNTGVSSLSLLQGIFPTQESNRGLAHIEARMKHINLSFAACGFLGIYHLGAASALYNHGRKLLKDVKACAGASAGSLVASVLLTAPQKIEECNKFIYDFAEEIRRQSFGALTPGYDFMARLRSGVESILPTNAHELAHGRLHVSITNTRTRRNCLVSSFPSREDLVKVLLASSFLPIYAGLKPVEYKGQRWVDGGFTNSLPVLPVGRTVTISPFSGRLDISPQDKGRLHFYVSITNQEVLLSVANLVRLNRALFPPSRRTMESLYQRGFDDASRFLVKENWFA", "length": 323, "header": "tr|A0ABI0P2E4-1|A0ABI0P2E4_BOVIN Isoform 1 of Patatin like phospholipase domain containing 4 OS=Bos taurus OX=9913 GN=PNPLA4 PE=4 SV=1 CANONICAL=A0ABI0P2E4-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NRM8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4/entry#A0ABI0NRM8-1", "sequence": { "sequence": "MLLCAEVSQTCVARMKHINLSFAACGFLGIYHLGAASALYNHGRKLLKDVKACAGASAGSLVASVLLTAPQKIEECNKFIYDFAEEIRRQSFGALTPGYDFMARLRSGVESILPTNAHELAHGRLHVSITNTRTRRNCLVSSFPSREDLVKVLLASSFLPIYAGLKPVEYKGQRWVDGGFTNSLPVLPVGRTVTISPFSGRLDISPQDKGRLHFYVSITNQEVLLSVANLVRLNRALFPPSRRTMESLYQRGFDDASRFLVKENWFA", "length": 267, "header": "tr|A0ABI0NRM8-1|A0ABI0P2E4_BOVIN Computationally mapped isoform of Patatin like phospholipase domain containing 4 OS=Bos taurus OX=9913 GN=PNPLA4 PE=4 SV=1 CANONICAL=A0ABI0P2E4-1" }, "locus": { "chromosome": "Y", "start_pos": 5207162, "end_pos": 5164300, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142399.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142399.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105410.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105410.1" } ] } }, { "isoform_ac": "A0ABI0NU21-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4/entry#A0ABI0NU21-1", "sequence": { "sequence": "MKHINLSFAACGFLGIYHLGAASALYNHGRKLLKDVKACAGASAGSLVASVLLTAPQKIEECNKFIYDFAEEIRRQSFGALTPGYDFMARLRSGVESILPTNAHELAHGRLHVSITNTRTRRNCLVSSFPSREDLVKVLLASSFLPIYAGLKPVEYKGQVTTERRVEFPALCRSFSSLVYVRHSVSSGDTSTAGSQVIPPRRPSSWSAYMCSLSQSLSALPEVGGRRLHQQPASPARRPHCDHLPVQWATGHLSAG", "length": 256, "header": "tr|A0ABI0NU21-1|A0ABI0P2E4_BOVIN Computationally mapped isoform of Patatin like phospholipase domain containing 4 OS=Bos taurus OX=9913 GN=PNPLA4 PE=4 SV=1 CANONICAL=A0ABI0P2E4-1" }, "locus": { "chromosome": "Y", "start_pos": 5204858, "end_pos": 5166622, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139035.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139035.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104537.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104537.1" } ] } }, { "isoform_ac": "A0ABI0NU97-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4/entry#A0ABI0NU97-1", "sequence": { "sequence": "MKHINLSFAACGFLGIYHLGAASALYNHGRKLLKDVKACAGASAGSLVASVLLTAPQKIEECNKFIYDFAEEIRRQSFGALTPGYDFMARLRSGVESILPTNAHELAHGRLHVSITNTRTRRNCLVSSFPSREDLVKRWVDGGFTNSLPVLPVGRTVTISPFSGRLDISPQDKGRLHFYVSITNQEVLLSVANLVRLNRALFPPSRRTMESLYQRGFDDASRFLVKENWFA", "length": 231, "header": "tr|A0ABI0NU97-1|A0ABI0P2E4_BOVIN Computationally mapped isoform of Patatin like phospholipase domain containing 4 OS=Bos taurus OX=9913 GN=PNPLA4 PE=4 SV=1 CANONICAL=A0ABI0P2E4-1" }, "locus": { "chromosome": "Y", "start_pos": 5204858, "end_pos": 5164300, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149499.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149499.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107253.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107253.1" } ] } }, { "isoform_ac": "A0ABI0NYE6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4/entry#A0ABI0NYE6-1", "sequence": { "sequence": "MKHINLSFAACGFLGIYHLGAASALYNHGRKLLKDVKACAGASAGSLVASVLLTAPQKIEECNKFIYDFAEEIRRQSFGALTPGYDFMARLRSGVESILPTNAHELAHGRLHVSITNTRTRRNCLVSSFPSREDLVKVLLASSFLPIYAGLKPVEYKGQRWVDGGFTNSLPVLPVGRTVTISPFSGRLDISPQDKGRLHFYVSITNQEVLPFRILRCAFLSQLSVANLVRLNRALFPPSRRTMESLYQRGFDDASRFLVKENWFA", "length": 265, "header": "tr|A0ABI0NYE6-1|A0ABI0P2E4_BOVIN Computationally mapped isoform of Patatin like phospholipase domain containing 4 OS=Bos taurus OX=9913 GN=PNPLA4 PE=4 SV=1 CANONICAL=A0ABI0P2E4-1" }, "locus": { "chromosome": "Y", "start_pos": 5204858, "end_pos": 5164300, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149451.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149451.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107260.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107260.1" } ] } }, { "isoform_ac": "A0ABI0P2E4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4/entry#A0ABI0P2E4-1", "sequence": { "sequence": "MLLCAEVSQTCVGDPLNPGIKPRSPALQTDSLPAESQGKPKNTGVSSLSLLQGIFPTQESNRGLAHIEARMKHINLSFAACGFLGIYHLGAASALYNHGRKLLKDVKACAGASAGSLVASVLLTAPQKIEECNKFIYDFAEEIRRQSFGALTPGYDFMARLRSGVESILPTNAHELAHGRLHVSITNTRTRRNCLVSSFPSREDLVKVLLASSFLPIYAGLKPVEYKGQRWVDGGFTNSLPVLPVGRTVTISPFSGRLDISPQDKGRLHFYVSITNQEVLLSVANLVRLNRALFPPSRRTMESLYQRGFDDASRFLVKENWFA", "length": 323, "header": "tr|A0ABI0P2E4-1|A0ABI0P2E4_BOVIN Isoform 1 of Patatin like phospholipase domain containing 4 OS=Bos taurus OX=9913 GN=PNPLA4 PE=4 SV=1 CANONICAL=A0ABI0P2E4-1" }, "locus": { "chromosome": "Y", "start_pos": 5207162, "end_pos": 5164300, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139755.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139755.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105219.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105219.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2E4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2E4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4" } ], "pmid": "" }, { "name": "retinyl-palmitate esterase activity", "id": "GO:0050253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050253", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2E4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2E4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P2E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2E4" }, { "id": "PS51635", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51635" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PNPLA", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 246, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P417-1", "uniprot_ac": "A0ABI0P417", "uniprot_id": "A0ABI0P417_BOVIN", "mass": { "chemical_mass": 60765.0, "monoisotopic_mass": 60765.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0P417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P417/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May function as a transcription factor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P417", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P417#function" }, { "database": "UniProtKB", "id": "ARBA00003729", "url": "https://www.uniprot.org/uniprotkb/ARBA00003729#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P417", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P417" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P417", "locus": {} } ], "crossref": [ { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NRZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P417", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P417", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P417-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P417-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAPWMSCEEEQEPEPQKSKGETKLENDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNVLNRVTPGSYSRRNRYGHFRKDNAQILQPVSHVTPTSEAKTVLPVSVSESRSTDSPIIIEPLSKADYKNISPQIVPNSFSELCSPLITFTSSLQHPVEIAVSAGAMDKSPHVSKLSTSETNSTSPKRPTLSDGIIGEHSLALSLSGIFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPLGGSVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELKRLRGDSWKYHTTCQHCHHQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQVLLQHMKDNHKPGEMPYVCQVYSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTAALYICHYRQHWAKSFHQCSKCWLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPG", "length": 542, "header": "tr|A0ABI0P417-1|A0ABI0P417_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P417-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NRZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P417/entry#A0ABI0NRZ3-1", "sequence": { "sequence": "MEAPWMSCEEEQEPEPQKSKGETKLENDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNVLNRVTPGSYSRRNRYGHFRKDNAQILQPVSHVTPTSEAKTVLPVSVSESRSTDSPIIIEPLSKADYKNISPQIVPNSFSELCSPLITFTSSLQHPVEIAVSAGAMDKSPHVSKLSTSETNSTSPKRPTLSDGIIGEHSLALSLSGIFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPLGGSVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELKRLRGDSWKYHTTCQHCHHQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQVLLQHMKDNHKPGEMPYVCQVYSIIILCRCGCTFQSIPW", "length": 424, "header": "tr|A0ABI0NRZ3-1|A0ABI0P417_BOVIN Computationally mapped isoform of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P417-1" }, "locus": { "chromosome": "Y", "start_pos": 25543099, "end_pos": 25541820, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151141.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151141.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105501.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105501.1" } ] } }, { "isoform_ac": "A0ABI0P417-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P417/entry#A0ABI0P417-1", "sequence": { "sequence": "MEAPWMSCEEEQEPEPQKSKGETKLENDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNVLNRVTPGSYSRRNRYGHFRKDNAQILQPVSHVTPTSEAKTVLPVSVSESRSTDSPIIIEPLSKADYKNISPQIVPNSFSELCSPLITFTSSLQHPVEIAVSAGAMDKSPHVSKLSTSETNSTSPKRPTLSDGIIGEHSLALSLSGIFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPLGGSVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELKRLRGDSWKYHTTCQHCHHQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQVLLQHMKDNHKPGEMPYVCQVYSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTAALYICHYRQHWAKSFHQCSKCWLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPG", "length": 542, "header": "tr|A0ABI0P417-1|A0ABI0P417_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P417-1" }, "locus": { "chromosome": "Y", "start_pos": 25543099, "end_pos": 25541471, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146644.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146644.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106269.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106269.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P417", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P417" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P417", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P417" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P417", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P417" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P417", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P417" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P417" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 342, "end_pos": 370, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 68, 96 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 522, "end_pos": 524 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of pro-inflammatory cytokines. 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"https://www.ensembl.org/id/ENSBTAP00000104069.1" } ] } }, { "isoform_ac": "A0ABI0P103-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P103/entry#A0ABI0P103-1", "sequence": { "sequence": "MKTMSITILFWLLSMLLLSDKSQTSKTEVKCNSTAKNYSLIPANISKNVTILDLSYNQITLNITDTRVLQTYFLLSELYLVENKVTNLFNNSFSNLSNLEILNICRNSIHTIQQSAFTGLHKLKKLYLCQNKIVQLNPKTFLPLKNLILLNLHGNLISYFDVPQLFHLEFIILYGNPWNCSCSLLNLQNWLKTSNVTLENESITMCSYPDILKCYNIKTVPYKAECYSKFPSSITEDLHIPFQSISNSTFNNSLNNLTRNSEHESHGKSWAFLVGVVVAVVMTSLLISIAIKCPVWYNFLLSYNHHRLEEHEAETYEDSFTGNPSSPSQIPDTNSEETTVIFDQLHSFVVDDDGFIEDKYIDTHELREEN", "length": 370, "header": "tr|A0ABI0P103-1|A0ABI0P103_BOVIN Isoform 1 of Leucine-rich repeat-containing protein 19 OS=Bos taurus OX=9913 GN=LRRC19 PE=4 SV=1 CANONICAL=A0ABI0P103-1" }, "locus": { "chromosome": "8", "start_pos": 17255244, "end_pos": 17251054, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139670.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139670.1" }, { "database": "Ensembl 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} ], "crossref": [ { "id": "IPR009431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR28546", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28546", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28546:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28546:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06387", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06387", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NSN1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSN1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0V9", "url": 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"tr|A0ABI0NSN1-1|A0ABI0P0V9_BOVIN Computationally mapped isoform of Calcyon neuron specific vesicular protein OS=Bos taurus OX=9913 GN=CALY PE=3 SV=1 CANONICAL=A0ABI0P0V9-1" }, "locus": { "chromosome": "26", "start_pos": 25676355, "end_pos": 25674366, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140552.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140552.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106045.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106045.1" } ] } }, { "isoform_ac": "A0ABI0P0V9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0V9/entry#A0ABI0P0V9-1", "sequence": { "sequence": "MVKLNCSFSGKTGSGDGGTMDSVPLISPLDVSQLQPSFADQVVIKTQTEYQLSSGDLSTKFSDLEGQKLSGGPEDVRSRMPTGRMIAFTMALMGCLLIMYKAIWYDQFSCPDGFLLRHKICTPLTLEMYYTELDPEHHRSLLAAIGAYPVGRKHGTETPWLSASYHAFKEGPRKASRAQARAAAAAAVTEPSRKPTGKPSGKPPGDASLQEEKEAAQKLAGSTPPPAPQ", "length": 229, "header": "tr|A0ABI0P0V9-1|A0ABI0P0V9_BOVIN Isoform 1 of Calcyon neuron specific vesicular protein OS=Bos taurus OX=9913 GN=CALY PE=3 SV=1 CANONICAL=A0ABI0P0V9-1" }, "locus": { "chromosome": "26", "start_pos": 25676935, "end_pos": 25674366, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154047.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154047.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104579.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104579.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0V9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0V9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "clathrin coat assembly", "id": "GO:0048268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048268", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0V9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0V9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "clathrin light chain binding", "id": "GO:0032051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032051", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0V9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0V9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P284-1", "uniprot_ac": "A0ABI0P284", "uniprot_id": "A0ABI0P284_BOVIN", "mass": { "chemical_mass": 29357.0, "monoisotopic_mass": 29357.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "14-3-3 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P284/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P284", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P284" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P284", "locus": {} } ], "crossref": [ { "id": "IPR000308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR18860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NUE9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUE9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P284", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P284", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P284-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P284-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDYVVHGVTKSQTGLSNFHFHCVSFAKRKDKLTLIQKANLAKQAKRYDDMATCLKAMMEQGAELSNEEHNLLSVAYKNVVWGRWSAWRKLQLIKDSRAKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIQLGLALNFSVFYYEILNNAELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN", "length": 259, "header": "tr|A0ABI0P284-1|A0ABI0P284_BOVIN Isoform 1 of 14-3-3 domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P284-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NUE9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P284/entry#A0ABI0NUE9-1", "sequence": { "sequence": "MRVLGADRELIQKANLAKQAKRYDDMATCLKAMMEQGAELSNEEHNLLSVAYKNVVWGRWSAWRKLQLIKDSRAKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIQLGLALNFSVFYYEILNNAELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN", "length": 235, "header": "tr|A0ABI0NUE9-1|A0ABI0P284_BOVIN Computationally mapped isoform of 14-3-3 domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P284-1" }, "locus": { "chromosome": "NKLS02000995.1", "start_pos": 37552, "end_pos": 36686, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078722.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078722.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107295.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107295.1" } ] } }, { "isoform_ac": "A0ABI0P284-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P284/entry#A0ABI0P284-1", "sequence": { "sequence": "MDYVVHGVTKSQTGLSNFHFHCVSFAKRKDKLTLIQKANLAKQAKRYDDMATCLKAMMEQGAELSNEEHNLLSVAYKNVVWGRWSAWRKLQLIKDSRAKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIQLGLALNFSVFYYEILNNAELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN", "length": 259, "header": "tr|A0ABI0P284-1|A0ABI0P284_BOVIN Isoform 1 of 14-3-3 domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P284-1" }, "locus": { "chromosome": "NKLS02000995.1", "start_pos": 37552, "end_pos": 36571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149195.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149195.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105448.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105448.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P284", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P284" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P284" }, { "id": "SM00101", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00101" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "14-3-3", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 256, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 187, "end_pos": 189 }, { "start_pos": 238, "end_pos": 240 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%), the beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases. 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"MVVLKGVPALLSPELLFALARMGHGDEIVLADVNFPSSSICRGGPEEIRADGLGIPQLLEAVLQLLPLDTYVQSPVRLLRALACPLPEHRGTTCPDGGGKDVCSRGPEPTRGALRAPRAGGLATEPSPSVSRLWSWSWCPATGRAAC", "length": 147, "header": "tr|A0ABI0NXB4-1|A0ABI0P3S4_BOVIN Computationally mapped isoform of Fucose mutarotase OS=Bos taurus OX=9913 GN=FUOM PE=3 SV=1 CANONICAL=A0ABI0P3S4-1" }, "locus": { "chromosome": "26", "start_pos": 25647666, "end_pos": 25645876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145958.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145958.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105422.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105422.1" } ] } }, { "isoform_ac": "A0ABI0P3S4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3S4/entry#A0ABI0P3S4-1", "sequence": { "sequence": "MVVLKGVPALLSPELLFALARMGHGDEIVLADVNFPSSSICRGGPEEIRADGLGIPQLLEAVLQLLPLDTYVQSPAMVMELVPSDRKSGLLTPVWTSYQSILSRAGYEFSLGMVERFAFYERAKKAFAVVATGETALYGNLILKKGVLAPKDLC", "length": 154, "header": "tr|A0ABI0P3S4-1|A0ABI0P3S4_BOVIN Isoform 1 of Fucose mutarotase OS=Bos taurus OX=9913 GN=FUOM PE=3 SV=1 CANONICAL=A0ABI0P3S4-1" }, "locus": { "chromosome": "26", "start_pos": 25648604, "end_pos": 25645876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151900.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151900.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105533.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105533.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "monosaccharide metabolic process", "id": "GO:0005996", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005996", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3S4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3S4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "monosaccharide binding", "id": "GO:0048029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048029", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3S4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3S4" } ], "pmid": "" }, { "name": "L-fucose mutarotase activity", "id": "GO:0036373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036373", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3S4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3S4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "25580", "name": "", "equation": "alpha-L-fucose = beta-L-fucose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0P563-1", "A0ABI0P3S4-1" ], "evidence": [ { "id": "25580", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25580" } ] } ], 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"name": "cysteine-rich and transmembrane domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059744423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059744423" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2V3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CYSTM1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V3", "locus": {} } ], "crossref": [ { "id": "777789", "url": "https://www.ncbi.nlm.nih.gov/gene/777789", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR043240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47564", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47564", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47564:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47564:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_059744423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059744423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NXE6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXE6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYZ2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYZ2-1", "database": "UniProtKB", 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Computationally mapped isoform of Cysteine-rich transmembrane module-containing protein 1 OS=Bos taurus OX=9913 GN=CYSTM1 PE=3 SV=1 CANONICAL=A0ABI0P2V3-1" }, "locus": { "chromosome": "7", "start_pos": 51434876, "end_pos": 51371602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151985.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151985.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105861.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105861.1" } ] } }, { "isoform_ac": "A0ABI0NYZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V3/entry#A0ABI0NYZ2-1", "sequence": { "sequence": "MDTATKMCTLQSLMNQGNPPPYPGPGPTAPYPPYPSQPMGPGFYPPGPPGGPYPPPQGGYPYQGYPQYGWQGGPQEPPKTTVYVVEDQRRDDLGTSTCLTACWTALCCCCLWDMLT", "length": 116, "header": "tr|A0ABI0NYZ2-1|A0ABI0P2V3_BOVIN Computationally mapped isoform of Cysteine-rich transmembrane module-containing protein 1 OS=Bos taurus OX=9913 GN=CYSTM1 PE=3 SV=1 CANONICAL=A0ABI0P2V3-1" }, "locus": { 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"https://www.ensembl.org/id/ENSBTAT00000145002.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104956.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104956.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 40, "start_aa": "Thr", "end_pos": 40, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr40", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": 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[provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376861" }, "gene_names": [ { "name": "OR4C10G", "type": "recommended", "evidence": [ { "id": "A0ABI0P0F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F7" } ] }, { "name": "OR4C10G", "type": "synonym", "evidence": [ { "id": "NP_001376861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376861" } ] }, { "name": "OR4C13", "type": "synonym", "evidence": [ { "id": "NP_001376861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376861" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0P0F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 4 subfamily C member 10G", "type": "synonym", "evidence": [ { "id": "NP_001376861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376861" } ] }, { "name": "olfactory receptor, family 4, subfamily C, member 13", "type": "synonym", "evidence": [ { "id": "NP_001376861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376861" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376861", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376861" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0F7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4C10G", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0F7", "locus": {} } ], "crossref": [ { "id": "cd15939", "url": 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"sequence": { "sequence": "GDSVNQKEGPVTVSEGALLTLNCTYQTTYSDLYVFWYVQHLNKAPQLLLKGWMKDQSPVREGFQATLVSTDSSFHSQKWAVETSDSAVYYCALSDTVREGCRGS", "length": 104, "header": "tr|A0ABI0P0K3-1|A0ABI0P0K3_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P0K3-1" }, "locus": { "chromosome": "10", "start_pos": 22855330, "end_pos": 22855019, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147657.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147657.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107718.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107718.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", 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Inhibits peroxisome proliferator-activated receptor (PPAR) activity by binding of its N-terminal to PPAR, preventing the latter's dimerization with retinoid X receptor. Essential for embryonic development.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0L4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0L4#function" }, { "database": "UniProtKB", "id": "ARBA00057946", "url": "https://www.uniprot.org/uniprotkb/ARBA00057946#function" } ] }, { "annotation": "Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0L4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0L4#function" }, { "database": "UniProtKB", "id": "RU367024", "url": "https://www.uniprot.org/uniprotkb/RU367024#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0L4", "url": 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[ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0L4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0L4" } ], "pmid": "" }, { "name": "dUTP diphosphatase activity", "id": "GO:0004170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004170", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0L4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0L4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10248", "name": "", "equation": "dUTP + H2O = dUMP + diphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1MT44-1", "A0ABI0P0L4-1" ], "evidence": [ { "id": "10248", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10248" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MT44", "gene_name": "DUT", "activity": [ { "ec_number": "3.6.1.23", "activity": "dUTP + H2O = dUMP + diphosphate + H(+).", "evidence": [ { "id": "A0A3Q1MT44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MT44" } ] }, { "ec_number": "3.6.1.23", "activity": "", "evidence": [ { "id": "A0A3Q1MT44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MT44" } ] } ] }, { "uniprot_ac": "A0ABI0P0L4", "gene_name": "", "activity": [ { "ec_number": "3.6.1.23", "activity": "dUTP + H2O = dUMP + diphosphate + H(+).", "evidence": [ { "id": "A0ABI0P0L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0L4" } ] }, { "ec_number": "3.6.1.23", "activity": "", "evidence": [ { "id": "A0ABI0P0L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0L4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P0L4", "database": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P0U9-1", "uniprot_ac": "A0ABI0P0U9", "uniprot_id": "A0ABI0P0U9_BOVIN", "mass": { "chemical_mass": 34666.0, "monoisotopic_mass": 34666.0 }, "refseq": { "ac": "NP_001376773", "name": "olfactory receptor family 2 subfamily AG member 2", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376773" }, "gene_names": [ { "name": "OR2AG2", "type": "recommended", "evidence": [ { "id": "A0ABI0P0U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0U9" } ] }, { "name": "OR2AG2", "type": "synonym", "evidence": [ { "id": "NP_001376773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376773" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 2 subfamily AG member 2", "type": "synonym", "evidence": [ { "id": "A0ABI0P0U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0U9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 2 subfamily AG member 2", "type": "synonym", "evidence": [ { "id": "NP_001376773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376773" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376773", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376773" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0U9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0U9#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0U9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0U9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR2AG2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0U9", "locus": {} } ], "crossref": [ { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "509651", "url": "https://www.ncbi.nlm.nih.gov/gene/509651", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein 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"evidence": [ { "id": "19937", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19937" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LMP5", "gene_name": "LOC112443696", "activity": [ { "ec_number": "2.1.1.20", "activity": "glycine + S-adenosyl-L-methionine = sarcosine + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A3Q1LMP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP5" } ] }, { "ec_number": "2.1.1.20", "activity": "", "evidence": [ { "id": "A0A3Q1LMP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP5" } ] } ] }, { "uniprot_ac": "A0ABI0P0W8", "gene_name": "GNMT", "activity": [ { "ec_number": "2.1.1.20", "activity": "glycine + S-adenosyl-L-methionine = sarcosine + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0ABI0P0W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0W8" } ] }, { "ec_number": "2.1.1.20", "activity": "", 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"https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.20" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377255" }, "gene_names": [ { "name": "OR7A105", "type": "recommended", "evidence": [ { "id": "A0ABI0P0Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Y0" } ] }, { "name": "OR7A105", "type": "synonym", "evidence": [ { "id": "NP_001377255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377255" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0P0Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Y0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 7A17", "type": "synonym", "evidence": [ { "id": "NP_001377255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377255" } ] }, { "name": "olfactory receptor family 7 subfamily A member 105", "type": "synonym", "evidence": [ { "id": "NP_001377255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377255" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377255", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377255" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0Y0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Y0#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P0Y0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Y0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR7A105", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0Y0", "locus": {} } ], "crossref": [ { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "782513", "url": "https://www.ncbi.nlm.nih.gov/gene/782513", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein 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[provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377668" }, "gene_names": [ { "name": "OR7C71", "type": "recommended", "evidence": [ { "id": "A0ABI0P183", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P183" } ] }, { "name": "OR7C71", "type": "synonym", "evidence": [ { "id": "NP_001377668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377668" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0P183", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P183/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 7 subfamily C member 71", "type": "synonym", "evidence": [ { "id": "NP_001377668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377668" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377668", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377668" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P183", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P183#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P183", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P183" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR7C71", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P183", "locus": {} } ], "crossref": [ { "id": "cd15234", "url": 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[provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376683", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376683" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1C3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C3#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1C3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR7A90", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1C3", "locus": {} } ], "crossref": [ { "id": "cd15234", "url": 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"database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10358", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10358", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10358:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10358:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04667", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04667", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059736109", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059736109", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0P1H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1H8-1", 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"Ensembl Transcript", "id": "ENSBTAT00000075206.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075206.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104135.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104135.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1H8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1H8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1H8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1H8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P1I8-1", "uniprot_ac": "A0ABI0P1I8", "uniprot_id": "A0ABI0P1I8_BOVIN", 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"id": "IPR052477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46272", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46272", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46272:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46272:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0ABI0P1I8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1I8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2L2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2L2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKSPPANAGDRGSIPGSGRSLGERNGSPLQCPRLENPMEEGAWRAAVHGVAKSRKELSDCTARSLFQGWVAISGHRGVTQEQSPGAEFKTLLRKAGLELGLQPAAQHPGAWRGEDPLSGGRGRPLISHLVLTARSAPQLALEQRCRELRARGRRLEETLPRRVSSEQQREALGLLCRVHELELEKAEMQSQALLRDGALRHRREALRCLEQRLSLCEEIIRAQRQLIQDGNLAVPQHLKELYEVYLREHEEGNLERATMMDRLASRALQDSALPKMSPPGTVPTPEESDLESVKMLNSESPHQHGSFLPLLGTESEANHLFKASSRAWQAKGSCLPTPPPILAGTLVTQEVTATQVGLNGQINSSPGSIENLSEIPLSHKGRKETAADTKSITGKAARHRSQALGAEGRQLLAPTMKQSSLSLHSLGETDDVWPPRPLACKRPPSPTLQHTASEDSLSSSTGEAPSRAVERHGDGPCPPLQGQKKSPRNKREESLEAKRKRRSQAFEVTGQGVSLEGQELGVSGPLPCRVLKAGLLQRPQGTTSCAPLSMECPPTEPNISLYQIPTQLPAHLALQPTQLSRPKMHVAGPRPVENHTEEQRMPVVGHLTPTIRPLGKTTLPMAKVKLPPCQSLGPEDTSPVAAPSNPGDVSERVARMPRLPYGTSTQGKNGRLGHN", "length": 676, "header": "tr|A0ABI0P1I8-1|A0ABI0P1I8_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC112442728 PE=4 SV=1 CANONICAL=A0ABI0P1I8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P1I8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1I8/entry#A0ABI0P1I8-1", "sequence": { "sequence": "MVKSPPANAGDRGSIPGSGRSLGERNGSPLQCPRLENPMEEGAWRAAVHGVAKSRKELSDCTARSLFQGWVAISGHRGVTQEQSPGAEFKTLLRKAGLELGLQPAAQHPGAWRGEDPLSGGRGRPLISHLVLTARSAPQLALEQRCRELRARGRRLEETLPRRVSSEQQREALGLLCRVHELELEKAEMQSQALLRDGALRHRREALRCLEQRLSLCEEIIRAQRQLIQDGNLAVPQHLKELYEVYLREHEEGNLERATMMDRLASRALQDSALPKMSPPGTVPTPEESDLESVKMLNSESPHQHGSFLPLLGTESEANHLFKASSRAWQAKGSCLPTPPPILAGTLVTQEVTATQVGLNGQINSSPGSIENLSEIPLSHKGRKETAADTKSITGKAARHRSQALGAEGRQLLAPTMKQSSLSLHSLGETDDVWPPRPLACKRPPSPTLQHTASEDSLSSSTGEAPSRAVERHGDGPCPPLQGQKKSPRNKREESLEAKRKRRSQAFEVTGQGVSLEGQELGVSGPLPCRVLKAGLLQRPQGTTSCAPLSMECPPTEPNISLYQIPTQLPAHLALQPTQLSRPKMHVAGPRPVENHTEEQRMPVVGHLTPTIRPLGKTTLPMAKVKLPPCQSLGPEDTSPVAAPSNPGDVSERVARMPRLPYGTSTQGKNGRLGHN", "length": 676, "header": "tr|A0ABI0P1I8-1|A0ABI0P1I8_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC112442728 PE=4 SV=1 CANONICAL=A0ABI0P1I8-1" }, "locus": { "chromosome": "19", "start_pos": 57064623, "end_pos": 57060727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141370.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141370.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104840.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104840.1" } ] } }, { "isoform_ac": "A0ABI0P2L2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1I8/entry#A0ABI0P2L2-1", "sequence": { "sequence": "MVKSPPANAGDRGSIPGSGRSLGERNGSPLQCPRLENPMEEGAWRAAVHGVAKSRKELSDCTARSLFQGWVAISGHRGVTQEQSPGAEFKTLLRKAGLELGLQPAAQHPGAWRGEDPLSGGRGRPLISHLVLTARSAPQLALEQRCRELRARGRRLEETLPRRVSSEQQREALGLLCRVHELELEKAEMQSQALLRDGALRHRREALRCLEQRLSLCEEIIRAQRQLIQDGNLAVPQHLKELYEVYLREHEEGNLERATMMDRLASRALQDSALPKMSPPGTVPTPEESDLESVKMLNSESPHQHGSFLPLLGTESEANHLFKASSRAWQAKGSCLPTPPPILAGTLVTQEVTATQVGLNGQINSSPGSIENLSEIPLSHKGRKETAADTKSITGKAARHRSQALGAEGRQLLAPTMKQSSLSLHSLGETDDVWPPRPLACKRPPSPTLQHTASEDSLSSSTGEAPSRAVERHGDGPCPPLQGQKKSPRNKREESLEAKRKRRSQAFEVTGQGIPTQLPAHLALQPTQLSRPKMHVAGPRPVENHTEEQRMPVVGHLTPTIRPLGKTTLPMAKVKLPPCQSLGPEDTSPVAAPSNPGDVSERVARMPRLPYGTSTQGKNGRLGHN", "length": 625, "header": "tr|A0ABI0P2L2-1|A0ABI0P2L2_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC112442728 PE=4 SV=1 CANONICAL=A0ABI0P1I8-1" }, "locus": { "chromosome": "19", "start_pos": 57064623, "end_pos": 57060727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147770.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147770.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107108.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107108.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 285, "start_aa": "Thr", "end_pos": 285, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr285", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1I8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1I8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1I8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1I8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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"MLGDLLLGDEAPNFEANTPIGRIRFHDYLGDSWGILSSHPRDFTTVCTTELGRAAKLAPEFAKRNVTMIALSIDSVEDHLAWSKDINAYNGEGPTEKLPFPIIDDKNRDLAIQLGMLDPAEKDEKDMPETSRVVFIFGPDKKLKLSILYPATTGRNFDEILRVIISLQLTAEKRVATPVDWKNGDSVMVLPTVPEEEAKKLFPKGVFTKELPSGKKYLRYTPQP", "length": 224, "header": "tr|A0ABI0P1I9-1|A0ABI0P1I9_BOVIN Isoform 1 of Peroxiredoxin-6 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P1I9-1" }, "locus": { "chromosome": "4", "start_pos": 83946734, "end_pos": 83946063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152588.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152588.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106889.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106889.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 95, "start_aa": "Thr", "end_pos": 95, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr95", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phospholipase A2 activity", "id": "GO:0004623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004623", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1I9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1I9" } ], "pmid": "" }, { "name": "peroxiredoxin activity", "id": "GO:0051920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051920", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1I9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1I9" } ], "pmid": "" }, { "name": "1-acylglycerophosphocholine O-acyltransferase activity", "id": "GO:0047184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047184", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1I9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1I9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12937", "name": "", "equation": "a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O77834-1", "Q3SZL3-1", "E1B770-1", "A0ABI0P1I9-1" ], "evidence": [ { "id": "12937", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12937" } ] }, { "id": "15801", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MFC1-1", "F1MG30-1", "E1BB89-1", "E1BC49-1", "Q8WMP9-1", "P00593-1", "A4IFJ5-1", "A0A3Q1LV96-1", "E1BLF3-1", "O77834-1", "E1B9V3-1", "E1BEG8-1", "A0AAA9T9W1-1", "Q56JZ2-1", "G3N3U6-1", "Q0VC00-1", "Q1JPB9-1", "Q2KI18-1", "A0A3Q1LNM7-1", "F1MNU5-1", "F1MSG5-1", "F6RTH3-1", "A0AAA9TQC6-1", "G5E5T0-1", "A0AAA9RYE9-1", "A0ABI0P1I9-1" ], "evidence": [ { "id": "15801", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15801" } ] }, { "id": "35983", "name": "", "equation": "1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O77834-1", "Q3SZL3-1", "A0ABI0P1I9-1" ], "evidence": [ { "id": "35983", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/35983" } ] }, { "id": "41223", "name": "", "equation": "1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q8WMP9-1", "P00593-1", "A0A3Q1LV96-1", "E1BLF3-1", "O77834-1", "Q56JZ2-1", "E1B9V3-1", "E1BEG8-1", "A0AAA9T9W1-1", "G3N3U6-1", "F6RTH3-1", "A0AAA9TQC6-1", "E1BB89-1", "A0ABI0P1I9-1" ], "evidence": [ { "id": "41223", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41223" } ] }, { "id": "62632", "name": "", "equation": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O77834-1", "F1N076-1", "A0A3Q1M314-1", "A0ABI0P1I9-1" ], "evidence": [ { "id": "62632", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/62632" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LNM7", "gene_name": "PLA2G2F", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LNM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNM7" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A3Q1LNM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNM7" } ] } ] }, { "uniprot_ac": "A0A3Q1LV96", "gene_name": "PLB1", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A3Q1LV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV96" } ] } ] }, { "uniprot_ac": "A0A3Q1M314", "gene_name": "HEPH", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A3Q1M314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M314" } ] }, { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "A0A3Q1M314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M314" } ] }, { "ec_number": "1.11.1.9", "activity": "2 glutathione + H2O2 = glutathione disulfide + 2 H2O.", "evidence": [ { "id": "A0A3Q1M314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M314" } ] }, { "ec_number": "1.16.3.4", "activity": "4 Cu(+) + O2 + 4 H(+) = 4 Cu(2+) + 2 H2O.", "evidence": [ { "id": "A0A3Q1M314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M314" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "A0A3Q1M314", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0AAA9RYE9" } ] } ] }, { "uniprot_ac": "A0AAA9T9W1", "gene_name": "PLA2G2C", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0AAA9T9W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9W1" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0AAA9T9W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9W1" } ] } ] }, { "uniprot_ac": "A0AAA9TQC6", "gene_name": "LOC613966", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0AAA9TQC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQC6" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0AAA9TQC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQC6" } ] } ] }, { "uniprot_ac": "A0ABI0P1I9", "gene_name": "", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "A0ABI0P1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1I9" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "A0ABI0P1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1I9" } ] } ] }, { "uniprot_ac": "A4IFJ5", "gene_name": "PLA2G4A", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A4IFJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFJ5" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A4IFJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFJ5" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A4IFJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFJ5" } ] } ] }, { "uniprot_ac": "E1B770", "gene_name": "LPCAT2", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] }, { "ec_number": "2.3.1.23", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] }, { "ec_number": "2.3.1.67", "activity": "a 1-O-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] }, { "ec_number": "2.3.1.25", "activity": "a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] }, { "ec_number": "2.3.1.23", "activity": "", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] }, { "ec_number": "2.3.1.25", "activity": "", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] }, { "ec_number": "2.3.1.67", "activity": "", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "E1B770", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B770" } ] } ] }, { "uniprot_ac": "E1B9V3", "gene_name": "LOC112443425", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1B9V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9V3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "E1B9V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9V3" } ] } ] }, { "uniprot_ac": "E1BB89", "gene_name": "PLA2G6", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] } ] }, { "uniprot_ac": "E1BC49", "gene_name": "PLA2G4B", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1BC49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC49" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "E1BC49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC49" } ] } ] }, { "uniprot_ac": "E1BEG8", "gene_name": "PLA2G5", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1BEG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEG8" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "E1BEG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEG8" } ] } ] }, { "uniprot_ac": "E1BLF3", "gene_name": "LOC615045", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1BLF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLF3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "E1BLF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLF3" } ] } ] }, { "uniprot_ac": "F1MFC1", "gene_name": "PLA2G4E", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "F1MFC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFC1" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "F1MFC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFC1" } ] } ] }, { "uniprot_ac": "F1MG30", "gene_name": "PLA2G4D", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "F1MG30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG30" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "F1MG30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG30" } ] } ] }, { "uniprot_ac": "F1MNU5", "gene_name": "PLA2G4F", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "F1MNU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU5" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "F1MNU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU5" } ] } ] }, { "uniprot_ac": "F1MSG5", "gene_name": "PLA2G2E", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "F1MSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG5" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "F1MSG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG5" } ] } ] }, { "uniprot_ac": "F1N076", "gene_name": "CP", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "F1N076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N076" } ] }, { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "F1N076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N076" } ] }, { "ec_number": "1.11.1.9", "activity": "2 glutathione + H2O2 = glutathione disulfide + 2 H2O.", "evidence": [ { "id": "F1N076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N076" } ] }, { "ec_number": "1.16.3.4", "activity": "4 Cu(+) + O2 + 4 H(+) = 4 Cu(2+) + 2 H2O.", "evidence": [ { "id": "F1N076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N076" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "F1N076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N076" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "F1N076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N076" } ] }, { "ec_number": "1.16.3.4", "activity": "", "evidence": [ { "id": "F1N076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N076" } ] }, { "ec_number": "1.11.1.9", "activity": "", "evidence": [ { "id": "F1N076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N076" } ] } ] }, { "uniprot_ac": "F6RTH3", "gene_name": "PLA2G2D4", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "F6RTH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RTH3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "F6RTH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RTH3" } ] } ] }, { "uniprot_ac": "G3N3U6", "gene_name": "PLA2G2D3", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "G3N3U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U6" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "G3N3U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U6" } ] } ] }, { "uniprot_ac": "G5E5T0", "gene_name": "PNPLA2", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "G5E5T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5T0" } ] } ] }, { "uniprot_ac": "O77834", "gene_name": "PRDX6", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] }, { "ec_number": "2.3.1.23", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "O77834", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O77834" } ] } ] }, { "uniprot_ac": "P00593", "gene_name": "PLA2G1B", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "P00593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00593" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "P00593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00593" } ] } ] }, { "uniprot_ac": "Q0VC00", "gene_name": "ABHD3", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "Q0VC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC00" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "Q0VC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC00" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "Q0VC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC00" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "Q0VC00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC00" } ] } ] }, { "uniprot_ac": "Q1JPB9", "gene_name": "PLA2G3", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "Q1JPB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPB9" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "Q1JPB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPB9" } ] } ] }, { "uniprot_ac": "Q2KI18", "gene_name": "PNPLA2", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "Q2KI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI18" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "Q2KI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI18" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "Q2KI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI18" } ] } ] }, { "uniprot_ac": "Q3SZL3", "gene_name": "LPCAT3", "activity": [ { "ec_number": "2.3.1.23", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "Q3SZL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZL3" } ] }, { "ec_number": "2.3.1.n6", "activity": "a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA.", "evidence": [ { "id": "Q3SZL3", "database": "UniProtKB", "url": 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"MPPQAPVWPSAPRERVRCPDHTGRRMVRGRPTGQLWTPLVQPTQGTECGAETLTDTVPPARLPCPQPAPGSSFSECRAPSWGPESPLTLDAPLAQTRSCWRELGSSLTGPRATGDPPKGTMAVMSPWVARGLWGEGRPGARRVPLASPQPHRSHTKTPTPLLPLPAECQNHTQAPSVHLLPPTPQGLWLLDKAEFTCLATGEAPLDACFSWEVNGQPHGGALEEGPTWHMNSSWSQSSRLALPRSLWASGSNVTCTLSGPCLRSPVTLMAQREHAASVPGNLTLRTVTAPGPFSHAWLLCEVSGFSPVDILLTWLESQQEVEPSQFATAHTTAQAGRASSHTWSVLRVSSPLDHAGATYTCVVSHEASRTLLNGSCSLDTGGLATWPPWSQDESSDDGTDVEDASPLWLTFLALFLVTVVYGGFVTFIKAGGPGRWGPMSRARAPRVGQDL", "length": 451, "header": "tr|A0ABI0P1N8-1|A0ABI0P1N8_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P1N8-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P1N8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1N8/entry#A0ABI0P1N8-1", "sequence": { "sequence": "MPPQAPVWPSAPRERVRCPDHTGRRMVRGRPTGQLWTPLVQPTQGTECGAETLTDTVPPARLPCPQPAPGSSFSECRAPSWGPESPLTLDAPLAQTRSCWRELGSSLTGPRATGDPPKGTMAVMSPWVARGLWGEGRPGARRVPLASPQPHRSHTKTPTPLLPLPAECQNHTQAPSVHLLPPTPQGLWLLDKAEFTCLATGEAPLDACFSWEVNGQPHGGALEEGPTWHMNSSWSQSSRLALPRSLWASGSNVTCTLSGPCLRSPVTLMAQREHAASVPGNLTLRTVTAPGPFSHAWLLCEVSGFSPVDILLTWLESQQEVEPSQFATAHTTAQAGRASSHTWSVLRVSSPLDHAGATYTCVVSHEASRTLLNGSCSLDTGGLATWPPWSQDESSDDGTDVEDASPLWLTFLALFLVTVVYGGFVTFIKAGGPGRWGPMSRARAPRVGQDL", "length": 451, "header": "tr|A0ABI0P1N8-1|A0ABI0P1N8_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P1N8-1" }, "locus": { "chromosome": "21", "start_pos": 129667, "end_pos": 124672, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143887.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143887.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106593.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106593.1" } ] } } ], "glycosylation": [ 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}, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 281, "end_pos": 283 }, { "start_pos": 373, "end_pos": 375 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P1P1-1", "uniprot_ac": "A0ABI0P1P1", "uniprot_id": "A0ABI0P1P1_BOVIN", "mass": { "chemical_mass": 60952.0, "monoisotopic_mass": 60952.0 }, "refseq": { "ac": "XP_059740301", "name": "zinc finger protein 280B-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740301" }, "gene_names": [ { "name": "LOC132344678", "type": "recommended", "evidence": [ { "id": "A0ABI0P1P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P1" } ] }, { "name": "LOC132344678", "type": "synonym", "evidence": [ { "id": "XP_059740301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740301" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0P1P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P1/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 280B-like", "type": "synonym", "evidence": [ { "id": "XP_059740301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740301" } ] } ], "function": [ { "annotation": "May function as a transcription factor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1P1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P1#function" }, { "database": "UniProtKB", "id": "ARBA00003729", "url": "https://www.uniprot.org/uniprotkb/ARBA00003729#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1P1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC132344678", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P1", "locus": {} } ], "crossref": [ { "id": "132344678", "url": "https://www.ncbi.nlm.nih.gov/gene/132344678", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059740301", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740301", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0P1P1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1P1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRVSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYRQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPG", "length": 543, "header": "tr|A0ABI0P1P1-1|A0ABI0P1P1_BOVIN Isoform 1 of C2H2-type domain-containing 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"start_pos": 30325085, "end_pos": 30323457, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138767.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138767.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104322.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104322.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1P1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1P1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1P1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1P1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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"id": "ENSBTAP00000107107.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107107.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1X0" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 143, 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P1Y0-1", "uniprot_ac": "A0ABI0P1Y0", "uniprot_id": "A0ABI0P1Y0_BOVIN", "mass": { "chemical_mass": 60942.0, "monoisotopic_mass": 60942.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0P1Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May function as a transcription factor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y0", "url": 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"UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYKQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKTG", "length": 543, "header": "tr|A0ABI0P1Y0-1|A0ABI0P1Y0_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P1Y0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P1Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y0/entry#A0ABI0P1Y0-1", "sequence": { "sequence": 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"ENSBTAP00000104743.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104743.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P1Y0", "database": "UniProtKB", "url": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P1Y3-1", "uniprot_ac": "A0ABI0P1Y3", "uniprot_id": "A0ABI0P1Y3_BOVIN", "mass": { "chemical_mass": 16681.0, "monoisotopic_mass": 16681.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ubiquitin-ribosomal protein eS31 fusion protein", "type": "recommended", "evidence": [ { "id": "A0ABI0P1Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the 40S subunit of the ribosome. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y3#function" }, { "database": "UniProtKB", "id": "ARBA00045528", "url": "https://www.uniprot.org/uniprotkb/ARBA00045528#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y3", "locus": {} } ], "crossref": [ { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050158", "url": 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"MQIFVKTLTGKTITLEVEPSDTEGIPPDQQRLIFAGKQLEDGCTLSDYNMQKESTLHLVLRLRGVAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGRISRLCQECPSDECGAGVFMTSHFDRHYCGKCCLTYCFNKPEDK", "length": 145, "header": "tr|A0ABI0P1Y3-1|A0ABI0P1Y3_BOVIN Isoform 1 of Ubiquitin-ribosomal protein eS31 fusion protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P1Y3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P1Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y3/entry#A0ABI0P1Y3-1", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTEGIPPDQQRLIFAGKQLEDGCTLSDYNMQKESTLHLVLRLRGVAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGRISRLCQECPSDECGAGVFMTSHFDRHYCGKCCLTYCFNKPEDK", "length": 145, "header": "tr|A0ABI0P1Y3-1|A0ABI0P1Y3_BOVIN Isoform 1 of Ubiquitin-ribosomal protein eS31 fusion protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P1Y3-1" }, "locus": { "chromosome": "8", "start_pos": 105411090, "end_pos": 105410623, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146829.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146829.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105459.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105459.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Y3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Y3" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { 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response that triggers the perception of a smell. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377493" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Z6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Z6#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P1Z6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Z6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR6C74C", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1Z6", "locus": {} } ], "crossref": [ { "id": "cd15912", "url": 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"LOC112446470", "type": "recommended", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ] } ], "protein_names": [ { "name": "ATP-dependent RNA helicase", "type": "recommended", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "ATP-dependent RNA helicase that plays a role in the regulation of R-loop homeostasis in both endogenous R-loop-prone regions and at sites of DNA damage. At endogenous loci such as actively transcribed genes, may act as a helicase to resolve the formation of R-loop during transcription and prevent the interference of R-loop with DNA-replication machinery. Also participates in the removal of DNA-lesion-associated R-loop. Plays an essential role for establishing pluripotency during embryogenesis and for pluripotency maintenance in embryonic stem cells. Mechanistically, prevents the polycomb repressive complex 2 (PRC2) from accessing rDNA loci and protects the active chromatin status in nucleolus.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P204", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204#function" }, { "database": "UniProtKB", "id": "ARBA00055930", "url": "https://www.uniprot.org/uniprotkb/ARBA00055930#function" } ] }, { "annotation": "RNA helicase.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P204", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204#function" }, { "database": "UniProtKB", "id": "RU365068", "url": "https://www.uniprot.org/uniprotkb/RU365068#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P204", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC112446470", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204", "locus": {} } ], "crossref": [ { "id": "cd17942", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17942", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24031", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24031", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13959", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13959", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0ABI0P204", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P204-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHLPMKLLRKKIEKRNLKLRQRNLKLQGASAVSLSETQNGDVPEETVGDGKVKKSLKQSVSVGLSEAPNGDIAKETVGSRKVKKSLKQPMSAGLAETQNGDTSEEAGVSGKVKKSRKQSMNASVSEASNRVLPREATENVKAKKSVKESVNVGMSEAQNGDVFKETGENVKVKKASKKSTTLTSGEAAMQSPNSESKKKKKKKKRKVVDDAGPDSKKAKAEDIGEAEDGAQAPEETENRVEKPDDEGEDSEVPSLPLGLTGAFEDTSFDSLTNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLKFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLANGINIVVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRKKKLMVFFSSCKSVKYHYELLNYIDLPVLAIHGRQKQNKRTTTFFQFCNADSGILLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRYLKQSKVPLSEFEFSWSKISDIQSQLEKLIEKNYFLHKSAQEAYKSYIRAYDSHSLKQIFNVNNLNLPQVALSFGFKVPPFVDLNVNTNDGKVRKRGGGGGFGYQKAKKVEKSKIFKHI", "length": 748, "header": "tr|A0ABI0P204-1|A0ABI0P204_BOVIN Isoform 1 of ATP-dependent RNA helicase OS=Bos taurus OX=9913 GN=LOC112446470 PE=3 SV=1 CANONICAL=A0ABI0P204-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P204-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204/entry#A0ABI0P204-1", "sequence": { "sequence": "MSHLPMKLLRKKIEKRNLKLRQRNLKLQGASAVSLSETQNGDVPEETVGDGKVKKSLKQSVSVGLSEAPNGDIAKETVGSRKVKKSLKQPMSAGLAETQNGDTSEEAGVSGKVKKSRKQSMNASVSEASNRVLPREATENVKAKKSVKESVNVGMSEAQNGDVFKETGENVKVKKASKKSTTLTSGEAAMQSPNSESKKKKKKKKRKVVDDAGPDSKKAKAEDIGEAEDGAQAPEETENRVEKPDDEGEDSEVPSLPLGLTGAFEDTSFDSLTNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLKFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLANGINIVVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRKKKLMVFFSSCKSVKYHYELLNYIDLPVLAIHGRQKQNKRTTTFFQFCNADSGILLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRYLKQSKVPLSEFEFSWSKISDIQSQLEKLIEKNYFLHKSAQEAYKSYIRAYDSHSLKQIFNVNNLNLPQVALSFGFKVPPFVDLNVNTNDGKVRKRGGGGGFGYQKAKKVEKSKIFKHI", "length": 748, "header": "tr|A0ABI0P204-1|A0ABI0P204_BOVIN Isoform 1 of ATP-dependent RNA helicase OS=Bos taurus OX=9913 GN=LOC112446470 PE=3 SV=1 CANONICAL=A0ABI0P204-1" }, "locus": { "chromosome": "4", "start_pos": 8737880, "end_pos": 8735637, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136120.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136120.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107163.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107163.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P204", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P204", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P204", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P204", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", "F1N2W9-1", "E1BB03-1", "E1BMP7-1", "A0JND9-1", "E1BAS6-1", "A0AAA9RXM7-1", "Q59HJ6-1", "Q2KJ94-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "A0AAF6Z0E4-1", "G3MZH7-1", "F1MKC7-1", "A0AAA9S7V9-1", "A0AAF6YME1-1", "F1MFR1-1", "Q3T084-1", "E1B7X9-1", "A0ABI0P204-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LG16", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] } ] }, { "uniprot_ac": "A0A3Q1LQC3", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] } ] }, { "uniprot_ac": "A0A3Q1LSH0", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] } ] }, { "uniprot_ac": "A0A3Q1LT80", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LT80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT80" } ] } ] }, { "uniprot_ac": "A0A3Q1LTL4", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTL4" } ] } ] }, { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1LXD0", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ 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{ "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDD8" } ] } ] }, { "uniprot_ac": "A0A3Q1MR04", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MR04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR04" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A3Q1MR04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR04" } ] } ] }, { "uniprot_ac": "A0A3Q1MR43", "gene_name": "DDX46", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MR43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1MR43", "database": "UniProtKB", "url": 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"A0ABI0P204", "gene_name": "LOC112446470", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P204", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P204" } ] } ] }, { "uniprot_ac": "A0ABI0P3F2", "gene_name": "DDX3Y", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P3F2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3F2" } ] } ] }, { "uniprot_ac": "A0ABI0P467", "gene_name": "SKIC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0ABI0P467", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P467" } ] } ] }, { "uniprot_ac": "A0JND9", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0JND9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JND9" } ] } ] }, { "uniprot_ac": "A1A4H6", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A1A4H6", "database": "UniProtKB", "url": 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{ "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A5D7C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7C1" } ] } ] }, { "uniprot_ac": "A5PJA1", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A5PJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJA1" } ] } ] }, { "uniprot_ac": "A5PJI5", "gene_name": "GET3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A5PJI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJI5" } ] } ] }, { "uniprot_ac": "A6QLE5", "gene_name": "NLRP3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A6QLE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLE5" } ] } ] }, { "uniprot_ac": "A6QLJ0", "gene_name": "ERCC2", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A6QLJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QLJ0" } ] } ] }, { "uniprot_ac": "A6QQR4", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A6QQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QQR4" } ] } ] }, { "uniprot_ac": "A7YSY2", "gene_name": "AFG2B", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A7YSY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7YSY2" } ] } ] }, { "uniprot_ac": "A7Z019", "gene_name": "SMARCA4", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A7Z019", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7Z019" } ] } ] }, { "uniprot_ac": "E1B7X9", "gene_name": "SMARCAD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1B7X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7X9" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B9N7", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1B9N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9N7" } ] } ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BAN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAN8" } ] } ] }, { "uniprot_ac": "E1BAS6", "gene_name": "SETX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] } ] }, { "uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": 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"5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "O18956", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] } ] }, { "uniprot_ac": "P09487", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.9.1.1", "activity": "N-phosphocreatine + H2O = creatine + phosphate.", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "P09487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09487" } ] } ] }, { "uniprot_ac": "P19120", "gene_name": "HSPA8", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "P19120", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19120" } ] } ] }, { "uniprot_ac": "P35071", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "P35071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35071" } ] } ] }, { "uniprot_ac": "P60712", "gene_name": "ACTB", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P60712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P60712" } ] } ] }, { "uniprot_ac": "P62739", "gene_name": "ACTA2", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P62739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62739" } ] } ] }, { "uniprot_ac": "P63258", "gene_name": "ACTG1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P63258" } ] } ] }, { "uniprot_ac": "P68138", "gene_name": "ACTA1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68138" } ] } ] }, { "uniprot_ac": "Q05B79", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] } ] }, { "uniprot_ac": "Q0IIK5", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + 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{ "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] } ] }, { "uniprot_ac": "Q2KJ94", "gene_name": "RAD51", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q2KJ94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ94" } ] } ] }, { "uniprot_ac": "Q2KJI7", "gene_name": "AFG3L2", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] } ] }, { "uniprot_ac": "Q2NKY8", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NKY8" } ] }, { "ec_number": "3.6.4.13", "activity": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P245-1", "uniprot_ac": "A0ABI0P245", "uniprot_id": "A0ABI0P245_BOVIN", "mass": { "chemical_mass": 36428.0, "monoisotopic_mass": 36428.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Testis-specific Y-encoded protein 1-like", "type": "recommended", "evidence": [ { "id": "A0ABI0P245", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P245/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P245", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P245" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P245", "locus": {} } ], "crossref": [ { "id": "IPR002164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11875", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11875", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00956", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00956", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0P245", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P245", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P245-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P245-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRPFASAPARGHRQGQEERERRSEEGGSVPGPRTFQVVSPVVTPGQEATLFRVEAVEEGEALVDGDVAGIGREFQLLEDIVEEVEVVADEEQEQRPSQELEEKTVEEQGQERPGGPCERQELDALQALAALQVELSSEREQNRRAYVQFMRKNHQRRKRHLARRSAIIQGIPGFWAKAIMSHPQVSVLISDQDQDFLGYMMDLKVQVRSHPPSRCKLVFSFRDNPYFLNSVIIKEYYLDITGYRARRSTPVHWFWDFEWGAPSRRLDTRSLNFLNWLSGHNGPESNRIAEIISEDVWDDPLKYYLREEGSSMRDN", "length": 316, "header": "tr|A0ABI0P245-1|A0ABI0P245_BOVIN Isoform 1 of Testis-specific Y-encoded protein 1-like OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P245-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P245-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P245/entry#A0ABI0P245-1", "sequence": { "sequence": "MSRPFASAPARGHRQGQEERERRSEEGGSVPGPRTFQVVSPVVTPGQEATLFRVEAVEEGEALVDGDVAGIGREFQLLEDIVEEVEVVADEEQEQRPSQELEEKTVEEQGQERPGGPCERQELDALQALAALQVELSSEREQNRRAYVQFMRKNHQRRKRHLARRSAIIQGIPGFWAKAIMSHPQVSVLISDQDQDFLGYMMDLKVQVRSHPPSRCKLVFSFRDNPYFLNSVIIKEYYLDITGYRARRSTPVHWFWDFEWGAPSRRLDTRSLNFLNWLSGHNGPESNRIAEIISEDVWDDPLKYYLREEGSSMRDN", "length": 316, "header": "tr|A0ABI0P245-1|A0ABI0P245_BOVIN Isoform 1 of Testis-specific Y-encoded protein 1-like OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P245-1" }, "locus": { "chromosome": "Y", "start_pos": 12996630, "end_pos": 12994384, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144843.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144843.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105534.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105534.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 44, "start_aa": "Thr", "end_pos": 44, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr44", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P245", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P245" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P245", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P245" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 44 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P249-1", "uniprot_ac": "A0ABI0P249", "uniprot_id": "A0ABI0P249_BOVIN", "mass": { "chemical_mass": 80301.0, "monoisotopic_mass": 80301.0 }, "refseq": { "ac": "XP_015328759", "name": "disintegrin and metalloproteinase domain-containing protein 21", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015328759" }, "gene_names": [ { "name": "ADAM21", "type": "recommended", "evidence": [ { "id": "A0ABI0P249", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P249" } ] }, { "name": "ADAM21", "type": "synonym", "evidence": [ { "id": "XP_015328759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015328759" } ] } ], "protein_names": [ { "name": "ADAM metallopeptidase domain 21", "type": "recommended", "evidence": [ { "id": "A0ABI0P249", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P249/entry#names_and_taxonomy" } ] }, { "name": "disintegrin and metalloproteinase domain-containing protein 21", "type": "synonym", "evidence": [ { "id": "XP_015328759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015328759" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P249", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P249" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ADAM21", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P249", "locus": {} } ], "crossref": [ { "id": "cd04269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532366", "url": "https://www.ncbi.nlm.nih.gov/gene/532366", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532366", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532366", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR11905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905:SF116", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905:SF116", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015328759", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015328759", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0P249", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P249", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P249-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P249-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVTGEARVSMQVVGLLWLEVSLFSSGLSQERRSQSLNSPDVVIPLKVTNGSRGPNAPGWLSYSLQFGGQRRVVYIRPKKILVSKALPVFTYTDQHALQQDQPFVPNDCYYHGYVEGVPESLVALSTCAGGFQGMLRINDFTYEIKPIRHSTTFEHLVSKINTKETQFSPMRCGLTNKAAHQQLEFKEAEKLTLKQNSAYNRWAHLWFLELVVVVDHNFFIYSQSNFSKVQENVFVVVNIVDSIYQQLGTYVILMGIEIWNYGNVFPLISIEQVLEDFSQWKQISLSQLQYDAAHIFIENSLISVLGIAYVAGICHPPLDCGVNNFKGDPWSVFALTVAHELGHTLGMKHDEEFCVCGQSACIMNAIRLPAERFTNCSYAEFTKTTLNQGSCLHNLPIPEAVFMLNHCGNGVIEGEEKCDCGSIKQCEQDPCCLLNCTLRPGAACAFGLCCKDCKFMPSGELCRPQINECDLPEWCNGTSHQCPEDVHVQDGIPCSDSAFCYQKSCNSHDEQCREIFGEGAKSASQRCYKEINSQGSRFGHCGVNGTTYLKCPISDSFCGRVHCENVGNIPHLRDHSNLQYTHINGVTCWSTDYHLEMSIPDIPDVGEVKDGTMCGPGKICIHKKCVSLSLLSRACLPETCNMKGICNNKHHCHCGYGWSPPYCLHRGTGGSVDSGPASARRAFLPTVVPLGLFVLLLPLIAVFMYLQKRFRPKKTKTHSPN", "length": 721, "header": "tr|A0ABI0P249-1|A0ABI0P249_BOVIN Isoform 1 of ADAM metallopeptidase domain 21 OS=Bos taurus OX=9913 GN=ADAM21 PE=4 SV=1 CANONICAL=A0ABI0P249-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P249-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P249/entry#A0ABI0P249-1", "sequence": { "sequence": "MVTGEARVSMQVVGLLWLEVSLFSSGLSQERRSQSLNSPDVVIPLKVTNGSRGPNAPGWLSYSLQFGGQRRVVYIRPKKILVSKALPVFTYTDQHALQQDQPFVPNDCYYHGYVEGVPESLVALSTCAGGFQGMLRINDFTYEIKPIRHSTTFEHLVSKINTKETQFSPMRCGLTNKAAHQQLEFKEAEKLTLKQNSAYNRWAHLWFLELVVVVDHNFFIYSQSNFSKVQENVFVVVNIVDSIYQQLGTYVILMGIEIWNYGNVFPLISIEQVLEDFSQWKQISLSQLQYDAAHIFIENSLISVLGIAYVAGICHPPLDCGVNNFKGDPWSVFALTVAHELGHTLGMKHDEEFCVCGQSACIMNAIRLPAERFTNCSYAEFTKTTLNQGSCLHNLPIPEAVFMLNHCGNGVIEGEEKCDCGSIKQCEQDPCCLLNCTLRPGAACAFGLCCKDCKFMPSGELCRPQINECDLPEWCNGTSHQCPEDVHVQDGIPCSDSAFCYQKSCNSHDEQCREIFGEGAKSASQRCYKEINSQGSRFGHCGVNGTTYLKCPISDSFCGRVHCENVGNIPHLRDHSNLQYTHINGVTCWSTDYHLEMSIPDIPDVGEVKDGTMCGPGKICIHKKCVSLSLLSRACLPETCNMKGICNNKHHCHCGYGWSPPYCLHRGTGGSVDSGPASARRAFLPTVVPLGLFVLLLPLIAVFMYLQKRFRPKKTKTHSPN", "length": 721, "header": "tr|A0ABI0P249-1|A0ABI0P249_BOVIN Isoform 1 of ADAM metallopeptidase domain 21 OS=Bos taurus OX=9913 GN=ADAM21 PE=4 SV=1 CANONICAL=A0ABI0P249-1" }, "locus": { "chromosome": "10", "start_pos": 82155771, "end_pos": 82153609, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142849.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142849.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107187.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107187.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:532366", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532366", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P249", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P249" } ], "pmid": "" }, { "name": "metal ion binding", "id": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376749", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376749" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P285", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P285#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P285", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P285" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR9G4D", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P285", "locus": {} } ], "crossref": [ { "id": "509124", "url": 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"MALKWINKELSDLARDPPAQCSAGPVEDDMFHWEATIMGPNDSPYQGGVFFLTIHFPTDYPFKLPKVAFTTRIYHPNINSNGSICLDILRSQWSPALIISKVLLSICSLLCDPNPDDPLVPEIARMYKTDRDKYNRVSREWTQKYAM", "length": 147, "header": "tr|A0ABI0P295-1|A0ABI0P295_BOVIN Isoform 1 of UBC core domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P295-1" }, "locus": { "chromosome": "Y", "start_pos": 55553395, "end_pos": 55552955, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141036.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141036.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106917.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106917.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P295", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P295" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P295", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P295" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P295", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P295" }, { "id": "PS50127", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50127" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBC core", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 147, "start_aa": "Met", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P2A1-1", "uniprot_ac": "A0ABI0P2A1", "uniprot_id": "A0ABI0P2A1_BOVIN", "mass": { "chemical_mass": 16893.0, "monoisotopic_mass": 16893.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0ABI0P2A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2A1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A1", "locus": {} } ], "crossref": [ { "id": "A0ABI0P2A1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2A1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKSEILLQDCSNSLRCRRTLLPLRPPKPVARPQRKEELHVRTFSTHHGVSLAGLLLPRPWTLKTSRPQTAPRGFPVSHSPEVLWDMQLLLAHSIPSLTGSSGHRVKHVQPPVLSSPFCTAREAGWKCLEACHTHILSLLGCLWFCTDSLP", "length": 151, "header": "tr|A0ABI0P2A1-1|A0ABI0P2A1_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P2A1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P2A1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2A1/entry#A0ABI0P2A1-1", "sequence": { "sequence": "MTKSEILLQDCSNSLRCRRTLLPLRPPKPVARPQRKEELHVRTFSTHHGVSLAGLLLPRPWTLKTSRPQTAPRGFPVSHSPEVLWDMQLLLAHSIPSLTGSSGHRVKHVQPPVLSSPFCTAREAGWKCLEACHTHILSLLGCLWFCTDSLP", "length": 151, "header": "tr|A0ABI0P2A1-1|A0ABI0P2A1_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P2A1-1" }, "locus": { "chromosome": "Y", "start_pos": 57382284, "end_pos": 57297528, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149786.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149786.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107308.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107308.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P2B4-1", "uniprot_ac": "A0ABI0P2B4", "uniprot_id": "A0ABI0P2B4_BOVIN", "mass": { "chemical_mass": 113605.0, "monoisotopic_mass": 113605.0 }, "refseq": {}, "gene_names": [ { "name": "LOC107131273", "type": "recommended", "evidence": [ { "id": "A0ABI0P2B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2B4" } ] } ], "protein_names": [ { "name": "Multidrug resistance-associated protein 4-like", "type": "recommended", "evidence": [ { "id": "A0ABI0P2B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2B4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2B4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2B4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC107131273", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2B4", "locus": {} } ], "crossref": [ { "id": "cd03250", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223:SF357", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223:SF357", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0P2B4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2B4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2B4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLIIIVFFFQEGTRVVQPIFLGKMVSYIENYDPANSAALHEAYGYAAGLSACVLVWAILHHLYFYHMQCVGMRLRVAVCHMIYRKSLRLSSSAMGKTTTGQIVNLLSNDVNRFDQVTMFLHYLWMGPLQAVAVTALLWKEIGMSCLAGMAVLIILLLLQSCFGMLFSSLRSKTAALTDDRIRTMTEVITGIRTVKMNAWEKSFIDLITRLRRKEISRILKSSYLRGMNLASFFAISKIMIFVTFITNELLDNRITASQVFVVVMLIEALRFSSTLYFPMAVEKVSEAVVSIRRIKNFLLLDEIPQVNTQLPSEGEVMVDMQDFTAFWDEESEIPTLQGLSFTVRPSELLAVVGPVGAGKSSLLSAVLGELPPSQGKVSVLGRIAYVSQQPWVFPGTVKNNILFGKKYEEERYEEVIKACALEENLKERDLTVTGDGGTPLSEGQKARVSLARAVYQDADIYLLDDPLSTVDAGISRHLFEQCIRQALKEKITILVTHQLQYLEDASQILILKDGKTVKRGTYSEFLKSRVDILSLFDNGNKQSEPSPVPGTPTLISKSLSWSLQSPRPSWKDVAPEDQDTENIQVTLPLEDQLERKVDFKTYASYFTAGAHWSVIIFLILVNIAAQARKGVYFDLCTQVDIYILFILHFMIIFVSLLLFYVLANSSQTLHNKMLESILRAPVLFFNRNPIGRILNRFSKDIGHMDDLLPQIFQDFIQTFLLVIGVMGVMVAVIPWVTVLVIPFGIIFFAIQWYFLRSSRDVKCLESAAQSPVFSHLASSLRGLGTIRAYKAEHKFQKLFDTYQDLHSEACFLLLTMSQQLAMYLDVICAIFVTVVAFAALILADTLNPGDVGLVLSLIITFTGMFQWCIRQSTEVENMMISVQRGIEYTDLEKEAPWELEYRPPPSWPHEGRIYITYVNFKYSLDGPLVLKNLDTLIDPREKRGIVGRTGAGKSSLITALFRLKKMSVAPQEPVLFTGTMRNNLDPFNEHTDEELWNALEERSLTV", 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] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P2I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2I1" }, { "id": "PF02994", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L1 transposable element RRM", "eco_id": "ECO_0000259", "start_pos": 143, "end_pos": 240, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P2I9-1", "uniprot_ac": "A0ABI0P2I9", "uniprot_id": "A0ABI0P2I9_BOVIN", "mass": { "chemical_mass": 97888.0, "monoisotopic_mass": 97888.0 }, "refseq": {}, "gene_names": [ { "name": "EGFEM1", "type": "recommended", "evidence": [ { "id": "A0ABI0P2I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2I9" } ] } ], "protein_names": [ { "name": "EGF-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0P2I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2I9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2I9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2I9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EGFEM1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2I9", "locus": {} } ], "crossref": [ { "id": "cd00055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013032", "database": "InterPro", "categories": [ "Protein 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07974", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07974", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0P2I9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2I9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2I9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2I9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "INTLGTFHCECDTGYRLHADERTCIKMDPCTGGNGCAHICQSENGVARCACHPGYQLSEDKKGCADINECAERLAPCSHRCVNTVGSFTCACQPGFELGADGKQCYRIELEIVNSCEKNNGGCSHHCEHAVGGPRCSCNHGHQLDSDEKTCIDLDECDSGEACCAQFCINYSGGYECSCQEGFQISSDGCGCDDVDECLDVSIICDQLCINSVGTYECSCEEGYRIGSDGKTCIFCLDNTFGHECSLSCEDCMNGGRCQEGKSGCSCPDGWGGILCNETRSPETSVRQYDDICDCQNGGTCDPLTGRCKCPPGVHGKTCGDGCPKGFFGKNCKRKCNCANNGHCHSVYGACLCEPGRYGRFCHLNCPKGAYGAGCSSECQCVEENTLECSARNGSCTCKSGYQGNRCQRVCSLGYFGPQVRTDLTMEDSAPFFLSRFILQACPDGLWGSACQFFCGPCENGGQCNKETGNCDCLPGYMGKACTLWQHSKPESGCPWLVGQVCMCSGGWIRTVCEKVSFPSFPLLSGCCCFLSPIIFGEDRLLYIYTDKFNSLGLHFLFPLVCPPGTYGKDCKQVCQCSAENEECHPVTGRCTCLPGYHGNRCHLRCPKGTYGPYCRRKCKCLNGGSCDTMIGTCDCLPGFIGADCSQTCPEDYYGQDCVQRCSCVSGQCDPVTGRCQCPPGQVGARCQQVCPPTKYGPNCELKCTCKNGGLCNPVDGSCTCALGWTGDYCEKECLPGYYGPGCHFNCTCQNNGVCNRFSGRCECLPGYHGRDCEHACLPGFYGLNCAHICDCKNGASCDAASGQCICLAGFHGNQCEKECSAGMFGDNCHQLCDCERESSCHPVTGKCLCPPGKTGGRCESECRSGQYGPNCSLKCRCTHTAHCDPLNGHCNCPPKRMGPTCEEDGLDDPQ", "length": 911, "header": 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"url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23268", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23268", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23268:SF101", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23268:SF101", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0P2K2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2K2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2K2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "DSGVTQTPKYLIKSRKQQVTLRCSPESGHLSVFWYQQALGQGPQFLVQYYDGKVYQKGNISDRVSGKQFSDAASELSLTPLELTDSAVYLCASSQDTALHDQAPLGQKQSCPSSGSGARVSAASLPSPVLVER", "length": 133, "header": "tr|A0ABI0P2K2-1|A0ABI0P2K2_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P2K2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P2K2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2K2/entry#A0ABI0P2K2-1", "sequence": { "sequence": "DSGVTQTPKYLIKSRKQQVTLRCSPESGHLSVFWYQQALGQGPQFLVQYYDGKVYQKGNISDRVSGKQFSDAASELSLTPLELTDSAVYLCASSQDTALHDQAPLGQKQSCPSSGSGARVSAASLPSPVLVER", "length": 133, "header": "tr|A0ABI0P2K2-1|A0ABI0P2K2_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P2K2-1" }, "locus": { "chromosome": "4", "start_pos": 105651865, "end_pos": 105651467, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136717.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136717.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105084.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105084.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2K2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2K2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P2K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2K2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 106, "start_aa": "Gln", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P3I3-1", "uniprot_ac": "A0ABI0P3I3", "uniprot_id": "A0ABI0P3I3_BOVIN", "mass": { "chemical_mass": 121799.0, "monoisotopic_mass": 121799.0 }, "refseq": { "ac": "XP_005224640", "name": "calpain-15 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224640" }, "gene_names": [ { "name": "CAPN15", "type": "recommended", "evidence": [ { "id": "A0ABI0P3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3I3" } ] }, { "name": "CAPN15", "type": "synonym", "evidence": [ { "id": "XP_005224640", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224640" } ] } ], "protein_names": [ { "name": "Calpain-15", "type": "recommended", "evidence": [ { "id": "A0ABI0P3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3I3/entry#names_and_taxonomy" } ] }, { "name": "Small optic lobes homolog", "type": "synonym", "evidence": [ { "id": "A0ABI0P3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3I3/entry#names_and_taxonomy" } ] }, { "name": "calpain-15 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005224640", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224640" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3I3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3I3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CAPN15", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3I3", "locus": {} } ], "crossref": [ { "id": "cd00044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "522068", "url": "https://www.ncbi.nlm.nih.gov/gene/522068", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:522068", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:522068", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR10183", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10183", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10183:SF382", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10183:SF382", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00641", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00641", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26741", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26741", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005224640", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224640", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0P2L4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2L4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3I3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3I3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3I3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5R3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5R3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5R3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSSASSLAAETESDHGFPRGPPCPGPPAAAGWGRSGPGGPAWGDSLGTRQHPPPRPRARSHTHSPGPMATVGEWACARCTFLNPAGQRQCSICEAPRHKPDLDRILRLSVEEQKWPCARCTFRNLLGRGACEMCGFTPEPGPGASPLPIINGVPPEPPGSCRDEAGPLRTAGPVAVEPAGGRPAEAEGQEGGAAAPGSGWACQRCTLHNTPVASSCSACGGPRKLSLPRIPPEALVVPEVMAPAGFPGTSAPAQPGEGAEANTPSAVDQEPPRGPPFSPFSPTLQNNPVPRSRREVPPQLQPPVPEAAQPSPSASSKGPPQGLGRPTTGASRLAELLSGKRLSFLEEEAAEGGPTLRPPGPASPAHCEAGSSTPGSDVIDLGGDSVRYTPASPSSPDFTTWSCARCTLRNPTATPRCTACGCSKLHGFQEHGDTTARCPDCSADRPGPCPAHKAGRPLPAAPSERPGQWACPACTLLNAPRAKHCATCHTPQLMAAQRRGVAPLRRRESVLVEKRRQTDEGEAKALWEDIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQRVRQWLRPHEINCSVFRDHSTSWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQVSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYESLGLRPRHAYSILDVRDVQGSRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRSELMPHGSSEGVFWMEYSDFVRYFDSVDICKVHSDWQEARVQGSFPSSASGPVGVTALTVLERASLEFALFQEGSRRADSVDSHLLDLCVLVFRASFGSGGRLSLGRLLAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWGPVPGPPALQASSPSAGAPRNTPEAPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKSYLHVQCDCSDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTTSKGSHSPPLTPEVAGLHGPRPL", "length": 1139, "header": "tr|A0ABI0P3I3-1|A0ABI0P3I3_BOVIN Isoform 1 of Calpain-15 OS=Bos taurus OX=9913 GN=CAPN15 PE=3 SV=1 CANONICAL=A0ABI0P3I3-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P2L4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3I3/entry#A0ABI0P2L4-1", "sequence": { "sequence": "MATVGEWACARCTFLNPAGQRQCSICEAPRHKPDLDRILRLSVEEQKWPCARCTFRNLLGRGACEMCGFTPEPGPGASPLPIINGVPPEPPGSCRDEAGPLRTAGPVAVEPAGGRPAEAEGQEGGAAAPGSGWACQRCTLHNTPVASSCSACGGPRKLSLPRIPPEALVVPEVMAPAGFPGTSAPAQPGEGAEANTPSAVDQEPPRGPPFSPFSPTLQNNPVPRSRREVPPQLQPPVPEAAQPSPSASSKGPPQGLGRPTTGASRLAELLSGKRLSFLEEEAAEGGPTLRPPGPASPAHCEAGSSTPGSDVIDLGGDSVRYTPASPSSPDFTTWSCARCTLRNPTATPRCTACGCSKLHGFQEHGDTTARCPDCSADRPGPCPAHKAGRPLPAAPSERPGQWACPACTLLNAPRAKHCATCHTPQLMAAQRRGVAPLRRRESVLVEKRRQTDEGEAKALWEDIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQRVRQWLRPHEINCSVFRDHSTSWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQVSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYESLGLRPRHAYSILDVRDVQGSRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRSELMPHGSSEGVFWMEYSDFVRYFDSVDICKVHSDWQEARVQGSFPSSASGPVGVTALTVLERASLEFALFQEGSRRADSVDSHLLDLCVLVFRASFGSGGRLSLGRLLAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWGPVPGPPALQASSPSAGAPRNTPEAPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKSYLHVQCDCSDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTTSKGSHSPPLTPEVAGLHGPRPL", 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0P2L7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2L7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVSDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNVLNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNLSPQIVPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGIIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPLGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTVFKCHSCLKVLKNVEFMNHMKHHLELERLRCDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYRQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPERKVVIQVSLEPLQPGLVEVASITVNASDSERSPPKSKSRRSKKPS", "length": 543, "header": "tr|A0ABI0P2L7-1|A0ABI0P2L7_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P2L7-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P2L7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L7/entry#A0ABI0P2L7-1", "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVSDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNVLNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNLSPQIVPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGIIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPLGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTVFKCHSCLKVLKNVEFMNHMKHHLELERLRCDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYRQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPERKVVIQVSLEPLQPGLVEVASITVNASDSERSPPKSKSRRSKKPS", "length": 543, "header": "tr|A0ABI0P2L7-1|A0ABI0P2L7_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P2L7-1" }, "locus": { "chromosome": "Y", "start_pos": 42799062, "end_pos": 42797434, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141628.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141628.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105629.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105629.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2L7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2L7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2L7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2L7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P2L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2L7" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 343, "end_pos": 371, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 68, 96 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 523, "end_pos": 525 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P2M0-1", "uniprot_ac": "A0ABI0P2M0", "uniprot_id": "A0ABI0P2M0_BOVIN", "mass": { "chemical_mass": 39434.0, "monoisotopic_mass": 39434.0 }, "refseq": { "ac": "NP_001179713", "name": "alpha-1,4-N-acetylglucosaminyltransferase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179713" }, "gene_names": [ { "name": "A4GNT", "type": "recommended", "evidence": [ { "id": "A0ABI0P2M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M0" } ] }, { "name": "A4GNT", "type": "synonym", "evidence": [ { "id": "NP_001179713", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179713" } ] } ], "protein_names": [ { "name": "Alpha-1,4-N-acetylglucosaminyltransferase", "type": "synonym", "evidence": [ { "id": "A0ABI0P2M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M0/entry#names_and_taxonomy" } ] }, { "name": "alpha-1,4-N-acetylglucosaminyltransferase", "type": "synonym", "evidence": [ { "id": "NP_001179713", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179713" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "A4GNT", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M0", "locus": {} } ], "crossref": [ { "id": "540795", "url": "https://www.ncbi.nlm.nih.gov/gene/540795", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540795", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540795", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR12042", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12042", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12042:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12042:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04488", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04488", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04572", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04572", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179713", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179713", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0P2M0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2M0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTKLQFSLSVTLLFACGFLYQFTLKPSCLICYLPSYKSHQGLEALLGRGHSIVFLETSERMEPTPLVSCAVESAAKVYPEQPVLLLMKGLNNSMQLPPNSTSPALSLLSAIDNVFLFPLDMKSLFEDTPLFSWYTQINSSTERFWLHISSDASRLAFIWKYGGVYMDTDVISIRPIPEDNFLAAQKSRFSSNGVFGFLPHHPFLWQCMENFVENYNPNIWGHQGPELMTRLLRVWCKLRDFQEVSDLKCLNFSFLHPQRFYPISFRAWRRYYEVWDTEPSFNNSYALHLWNHMNQEGKAVVRGSNTLVEHLYRKHCPKTYRDLLQGPEGSVTREQSPGNK", "length": 341, "header": "tr|A0ABI0P2M0-1|A0ABI0P2M0_BOVIN Isoform 1 of Alpha-1,4-N-acetylglucosaminyltransferase OS=Bos taurus OX=9913 GN=A4GNT PE=3 SV=1 CANONICAL=A0ABI0P2M0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P2M0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2M0/entry#A0ABI0P2M0-1", "sequence": { "sequence": "MLTKLQFSLSVTLLFACGFLYQFTLKPSCLICYLPSYKSHQGLEALLGRGHSIVFLETSERMEPTPLVSCAVESAAKVYPEQPVLLLMKGLNNSMQLPPNSTSPALSLLSAIDNVFLFPLDMKSLFEDTPLFSWYTQINSSTERFWLHISSDASRLAFIWKYGGVYMDTDVISIRPIPEDNFLAAQKSRFSSNGVFGFLPHHPFLWQCMENFVENYNPNIWGHQGPELMTRLLRVWCKLRDFQEVSDLKCLNFSFLHPQRFYPISFRAWRRYYEVWDTEPSFNNSYALHLWNHMNQEGKAVVRGSNTLVEHLYRKHCPKTYRDLLQGPEGSVTREQSPGNK", "length": 341, "header": "tr|A0ABI0P2M0-1|A0ABI0P2M0_BOVIN Isoform 1 of Alpha-1,4-N-acetylglucosaminyltransferase OS=Bos taurus OX=9913 GN=A4GNT PE=3 SV=1 CANONICAL=A0ABI0P2M0-1" }, "locus": { "chromosome": "1", "start_pos": 131008082, "end_pos": 131003440, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152864.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152864.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104693.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104693.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376700" }, "gene_names": [ { "name": "OR2AG1G", "type": "recommended", "evidence": [ { "id": "A0ABI0P2Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Q3" } ] }, { "name": "OR2AG1G", "type": "synonym", "evidence": [ { "id": "NP_001376700", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376700" } ] }, { "name": "OR2AG1", "type": "synonym", "evidence": [ { "id": "NP_001376700", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376700" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 2 subfamily AG member 1G", "type": "synonym", "evidence": [ { "id": "A0ABI0P2Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Q3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 2 subfamily AG member 1G", "type": "synonym", "evidence": [ { "id": "NP_001376700", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376700" } ] }, { "name": "olfactory receptor, family 2, subfamily AG, member 1", "type": "synonym", "evidence": [ { "id": "NP_001376700", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376700" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "506162", "url": "https://www.ncbi.nlm.nih.gov/gene/506162", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein 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"https://www.ensembl.org/id/ENSBTAP00000107614.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2S9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small molecule binding", "id": "GO:0036094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036094", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2S9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P2S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S9" }, { "id": "PF00061", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lipocalin/cytosolic fatty-acid binding", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 166, "start_aa": "Ser", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"crossref": [ { "id": "A0ABI0P2U1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2U1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2U1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2U1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSEILLQRDCSNSLRCRRTLLPLRPPKPVARPQRKEELHVRTFSTHHGVSLAGLLLPRPWTLKTSRPRTAPRGFPVSHSPEVLWDMQLLLAHSIPSPTGSSGHRVKHVQPPVLSSPFCTAREAGWKCLEACHTQILSLLGCLWFCTDSLP", "length": 151, "header": "tr|A0ABI0P2U1-1|A0ABI0P2U1_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P2U1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P2U1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2U1/entry#A0ABI0P2U1-1", "sequence": { "sequence": "MTSEILLQRDCSNSLRCRRTLLPLRPPKPVARPQRKEELHVRTFSTHHGVSLAGLLLPRPWTLKTSRPRTAPRGFPVSHSPEVLWDMQLLLAHSIPSPTGSSGHRVKHVQPPVLSSPFCTAREAGWKCLEACHTQILSLLGCLWFCTDSLP", "length": 151, "header": "tr|A0ABI0P2U1-1|A0ABI0P2U1_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P2U1-1" }, "locus": { "chromosome": "Y", "start_pos": 34936562, "end_pos": 34847418, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147013.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147013.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104550.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104550.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P2V2-1", "uniprot_ac": "A0ABI0P2V2", "uniprot_id": "A0ABI0P2V2_BOVIN", "mass": { "chemical_mass": 60926.0, "monoisotopic_mass": 60926.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0P2V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May function as a transcription factor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2V2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V2#function" }, { "database": "UniProtKB", "id": "ARBA00003729", "url": "https://www.uniprot.org/uniprotkb/ARBA00003729#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P2V2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V2", "locus": {} } ], "crossref": [ { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0P2V2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2V2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYHGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYICQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYKQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPG", "length": 543, "header": "tr|A0ABI0P2V2-1|A0ABI0P2V2_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P2V2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P2V2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2V2/entry#A0ABI0P2V2-1", "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKNISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPVGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYHGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYICQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYKQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPG", "length": 543, "header": "tr|A0ABI0P2V2-1|A0ABI0P2V2_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P2V2-1" }, "locus": { "chromosome": "Y", "start_pos": 39506440, "end_pos": 39504812, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140159.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140159.1" }, { "database": "Ensembl Peptide", "id": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377610" }, "gene_names": [ { "name": "OR4C185", "type": "recommended", "evidence": [ { "id": "A0ABI0P3H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3H8" } ] }, { "name": "OR4C185", "type": "synonym", "evidence": [ { "id": "NP_001377610", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377610" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 4 subfamily C member 185", "type": "synonym", "evidence": [ { "id": "A0ABI0P3H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3H8/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 4 subfamily C member 185", "type": "synonym", "evidence": [ { "id": "NP_001377610", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377610" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"uniprot_ac": "A0A3Q1MI36", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] } ] }, { "uniprot_ac": "A0A3Q1MKC7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] } ] }, { "uniprot_ac": "Q3T0N5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q3T0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0N5" } ] } ] }, { "uniprot_ac": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P3W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3W0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P3Z3-1", "uniprot_ac": "A0ABI0P3Z3", "uniprot_id": "A0ABI0P3Z3_BOVIN", "mass": { "chemical_mass": 86359.0, "monoisotopic_mass": 86359.0 }, "refseq": {}, "gene_names": [ { "name": "PCDHB5", "type": "recommended", "evidence": [ { "id": "A0ABI0P3Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Z3" } ] } ], "protein_names": [ { "name": "Protocadherin beta 5", "type": "synonym", "evidence": [ { "id": "A0ABI0P3Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Z3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P3Z3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Z3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PCDHB5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3Z3", "locus": {} } ], "crossref": [ { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF90", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF90", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16492", 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"locus": { "chromosome": "3", "start_pos": 91344401, "end_pos": 91332043, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140820.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140820.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105887.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105887.1" } ] } }, { "isoform_ac": "A0ABI0P5W5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P463/entry#A0ABI0P5W5-1", "sequence": { "sequence": "MTAPKTCDRARVASTLRYCMMVSGTVVLVAGTLCFAWWSEGDAGPPPGQSAPPTGCPEPGAPGALLRSVSFFCCGAGGLLLLFGLLWSVKASTQKLPRWDPYHLSRDLYYLTVESSEKQSCRTPKVITVPTYEEAVCCPLAGGPLILPASPVEEDLERSASGDALPGAQPPLPPPSYESLIFAAGGISGETARGAACSLTGPVQITEGGS", "length": 210, "header": "tr|A0ABI0P5W5-1|A0ABI0P5W5_BOVIN Computationally mapped isoform of Transmembrane protein 61 OS=Bos taurus OX=9913 GN=TMEM61 PE=4 SV=1 CANONICAL=A0ABI0P463-1" }, "locus": { "chromosome": "3", "start_pos": 91344401, "end_pos": 91332043, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138217.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138217.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106623.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106623.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:615684", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615684", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P468-1", "uniprot_ac": "A0ABI0P468", "uniprot_id": "A0ABI0P468_BOVIN", "mass": { "chemical_mass": 16903.0, "monoisotopic_mass": 16903.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0ABI0P468", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P468/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P468", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P468" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P468", "locus": {} } ], "crossref": [ { "id": "A0ABI0P468", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P468", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P468-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P468-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKSEILLQQDCSNSFRCRRTLLLLRPPKPVARPQRKEELHVRTFSTHHGVSLAGLLLPRPWTLKTSRPQTAPRGFPVSHSPEVLWDMQLLLAHSVPSLTGSSGQRVKHVQPPVLSSPFCTAREAGWKCLEACHAHILSLLGCLVCRYSLL", "length": 151, "header": "tr|A0ABI0P468-1|A0ABI0P468_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P468-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P468-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P468/entry#A0ABI0P468-1", "sequence": { "sequence": "MTKSEILLQQDCSNSFRCRRTLLLLRPPKPVARPQRKEELHVRTFSTHHGVSLAGLLLPRPWTLKTSRPQTAPRGFPVSHSPEVLWDMQLLLAHSVPSLTGSSGQRVKHVQPPVLSSPFCTAREAGWKCLEACHAHILSLLGCLVCRYSLL", "length": 151, "header": "tr|A0ABI0P468-1|A0ABI0P468_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P468-1" }, "locus": { "chromosome": "Y", "start_pos": 25588460, "end_pos": 25588005, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147642.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147642.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105622.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105622.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], 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"A0ABI0P484", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P484" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P484", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P484" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P484", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P484" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 85, "end_pos": 145, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 217, "end_pos": 219 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P496-1", "uniprot_ac": "A0ABI0P496", "uniprot_id": "A0ABI0P496_BOVIN", "mass": { "chemical_mass": 17293.0, "monoisotopic_mass": 17293.0 }, "refseq": {}, "gene_names": [ { "name": "EIF1AY", "type": "recommended", "evidence": [ { "id": "A0ABI0P496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P496" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 4C", "type": "recommended", "evidence": [ { "id": "A0ABI0P496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P496/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P496", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P496#function" }, { "database": "UniProtKB", "id": "ARBA00045454", "url": "https://www.uniprot.org/uniprotkb/ARBA00045454#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P496", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P496" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EIF1AY", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P496", "locus": {} } ], "crossref": [ { "id": "cd05793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001253", "url": 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] } ], "sequence": { "sequence": "MPKNKGKGGRNRRKGKKENEYEKRDLVFKEDGQEYAQVTKMLGNARLEAMCFDGVTRICHIRGSLRKKVWINTSDIILIGLRDYQDNKADVILKYNADEARSLKAYGELPEYAELSETDTFDAEDDDEIQFKDPAGEDEDMEVYELNSEV", "length": 150, "header": "tr|A0ABI0P496-1|A0ABI0P496_BOVIN Isoform 1 of Eukaryotic translation initiation factor 4C OS=Bos taurus OX=9913 GN=EIF1AY PE=3 SV=1 CANONICAL=A0ABI0P496-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P496-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P496/entry#A0ABI0P496-1", "sequence": { "sequence": "MPKNKGKGGRNRRKGKKENEYEKRDLVFKEDGQEYAQVTKMLGNARLEAMCFDGVTRICHIRGSLRKKVWINTSDIILIGLRDYQDNKADVILKYNADEARSLKAYGELPEYAELSETDTFDAEDDDEIQFKDPAGEDEDMEVYELNSEV", "length": 150, "header": "tr|A0ABI0P496-1|A0ABI0P496_BOVIN Isoform 1 of Eukaryotic translation initiation factor 4C OS=Bos taurus OX=9913 GN=EIF1AY PE=3 SV=1 CANONICAL=A0ABI0P496-1" }, "locus": { "chromosome": "Y", "start_pos": 6894763, "end_pos": 6878545, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P497-1", "uniprot_ac": "A0ABI0P497", "uniprot_id": "A0ABI0P497_BOVIN", "mass": { "chemical_mass": 35450.0, "monoisotopic_mass": 35450.0 }, "refseq": { "ac": "NP_001377569", "name": "olfactory receptor family 10 subfamily A member 5", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377569" }, "gene_names": [ { "name": "OR10A5", "type": "recommended", "evidence": [ { "id": "A0ABI0P497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P497" } ] }, { "name": "OR10A5", "type": "synonym", "evidence": [ { "id": "NP_001377569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377569" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0P497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P497/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 10A2", "type": "synonym", "evidence": [ { "id": "NP_001377569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377569" } ] }, { "name": "olfactory receptor family 10 subfamily A member 5", "type": "synonym", "evidence": [ { "id": "NP_001377569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377569" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377569" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P497", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P497#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P497", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P497" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR10A5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P497", "locus": {} } ], "crossref": [ { "id": "cd15225", "url": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377606" }, "gene_names": [ { "name": "OR8U3", "type": "recommended", "evidence": [ { "id": "A0ABI0P4F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4F1" } ] }, { "name": "OR5R1", "type": "synonym", "evidence": [ { "id": "NP_001377606", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377606" } ] }, { "name": "OR8U3", "type": "synonym", "evidence": [ { "id": "NP_001377606", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377606" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0ABI0P4F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4F1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1038", "type": "synonym", "evidence": [ { "id": "NP_001377606", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377606" } ] }, { "name": "olfactory receptor 8U3", "type": "synonym", "evidence": [ { "id": "NP_001377606", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377606" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377606", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377606" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4F1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4F1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4F1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4F1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR8U3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4F1", "locus": {} } ], "crossref": [ { "id": "cd15413", "url": 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"tr|A0ABI0P4N9-1|A0ABI0P4N9_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC132344525 PE=4 SV=1 CANONICAL=A0ABI0P4N9-1" }, "locus": { "chromosome": "Y", "start_pos": 25427012, "end_pos": 25424451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143454.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143454.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106728.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106728.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P4P2-1", "uniprot_ac": "A0ABI0P4P2", "uniprot_id": "A0ABI0P4P2_BOVIN", "mass": { "chemical_mass": 60979.0, "monoisotopic_mass": 60979.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0ABI0P4P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May function as a transcription factor.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4P2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P2#function" }, { "database": "UniProtKB", "id": "ARBA00003729", "url": "https://www.uniprot.org/uniprotkb/ARBA00003729#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4P2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P2", "locus": {} } ], "crossref": [ { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0P4P2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4P2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKIISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPLGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYRQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPG", "length": 543, "header": "tr|A0ABI0P4P2-1|A0ABI0P4P2_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P4P2-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P4P2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P2/entry#A0ABI0P4P2-1", "sequence": { "sequence": "MEPPWMSCEEEQEPEPQKSEGETKLVNDEDAELILVGVEHVHEDDDVIFVGMTSNSKPVISNILNRVTPGSCSRRNRYGHFRKDNAQKLQPVSHVTPTSEAKTVLPLSVSESRSTDSPIIIEPLSKADSKIISPQIMPNSFSELCSPLITFTSSLQHPVETAVSAGDMDKSPRVSKRLSTSETNSTSPKRPTLSDGVIGEHSLALSLSGTFHTVTTQQSTPDSVHNSLSHVQSGEPCPTAFPKDNVHCKPVSPLGGNVLTKTDFPSVSSQNKFADPTEGNLIVLLRDFYYGQHIGDGQPEPKTHTAFKCHSCLKVLKNVEFMNHMKHHLELERLRGDSWKYHTTCQHCHRQFPTPFQLQCHIESVHTSQEPCTVCKICELSFEADQILLQHMKDNHKPGEMPYVCQVCSYRSSFFADVDAHFRAYHGNTKNLLCPFCLQIFKTEALYICHYRQHWAKRFHQCSKCRLQFLTCKEKREHKTQCHQMFKKPKQLEGLPPETKVVIQVSLEPLQPGLVEVASITVNASDSEPSPPKSKSRRSKKPG", "length": 543, "header": "tr|A0ABI0P4P2-1|A0ABI0P4P2_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P4P2-1" }, "locus": { "chromosome": "Y", "start_pos": 35404545, "end_pos": 35402917, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154077.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154077.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105987.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105987.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4P2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4P2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4P2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P4P2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P4P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4P2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 343, "end_pos": 371, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 68, 96 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 }, { "start_pos": 523, "end_pos": 525 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] 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triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"ENSBTAP00000106487.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106487.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P533", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P533" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P533", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P533" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P533", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P533" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P533", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P533" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P533", "database": "UniProtKB", "url": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P544-1", "uniprot_ac": "A0ABI0P544", "uniprot_id": "A0ABI0P544_BOVIN", "mass": { "chemical_mass": 36368.0, "monoisotopic_mass": 36368.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Calponin", "type": "recommended", "evidence": [ { "id": "A0ABI0P544", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P544/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P544", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P544#function" }, { "database": "UniProtKB", "id": "RU361224", "url": "https://www.uniprot.org/uniprotkb/RU361224#function" }, { "database": "UniProtKB", "id": "ARBA00025109", "url": "https://www.uniprot.org/uniprotkb/ARBA00025109#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P544", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P544" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P544", "locus": {} } ], "crossref": [ { "id": "cd21284", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21284", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000557", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000557", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47385", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47385", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47385:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47385:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0P544", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P544", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P544-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P544-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHFNKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGANFQLGLKDGIILCELINKLQPGPVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNSTISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQAEYPDEYHGEYQDDYPRDYQYGDQGIDY", "length": 329, "header": "tr|A0ABI0P544-1|A0ABI0P544_BOVIN Isoform 1 of Calponin OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P544-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P544-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P544/entry#A0ABI0P544-1", "sequence": { "sequence": "MTHFNKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGANFQLGLKDGIILCELINKLQPGPVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNSTISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQAEYPDEYHGEYQDDYPRDYQYGDQGIDY", "length": 329, "header": "tr|A0ABI0P544-1|A0ABI0P544_BOVIN Isoform 1 of Calponin OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P544-1" }, "locus": { "chromosome": "3", "start_pos": 19221967, "end_pos": 19220981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141298.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141298.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106610.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106610.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P544", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P544" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": 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[], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P544", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P544" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 130, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 240, "end_pos": 242 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 74, "end_pos": 76 } ] 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"MAHIPSEIQDGPPKDESTDSETSIRSLYDYTLTRDSVLRSMIEEYAFQALSEDLVIKRPCYKYSVSETDEVTNFLSLTFPQKLWNIVESDQFESIWWDERGTCIVIHEELFKKEVLERKAPFRIFETKSMKSLIRQLNLYGFSKKQTFQRSASLPVFLEEENNISLLSKLQTYYNPNFKRGHPQLLLRVQRRERRVGINNVSQISSLVQDNKKHVKASVNEDDRNSEFIPEISRESAFSASTSLPVPFIQKPHTIQIVTNKNALYPCDLPNHPSPISVRQTEQILVNQPAVLKKLSIFNWHSHSSYTQVNGPIEDFATTTTSTSQNHIVSPLQSTYSGLMVEPSKFPVRHSDMSGHDNPFPNLQETGNSWFSVPTSTYTSASSLSSQLINNHHYMETMLIKTDLPNTCQIMEPKED", "length": 416, "header": "tr|A0ABI0P592-1|A0ABI0P592_BOVIN Isoform 1 of HSF-type DNA-binding domain-containing protein OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0ABI0P592-1" }, "locus": { "chromosome": "Y", "start_pos": 47589462, "end_pos": 47587782, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138202.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138202.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106687.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106687.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P592", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P592" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P592", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P592" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P592", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P592" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P592" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 192, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 200, "end_pos": 202 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P5S2-1", "uniprot_ac": "A0ABI0P5S2", "uniprot_id": "A0ABI0P5S2_BOVIN", "mass": { "chemical_mass": 27530.0, "monoisotopic_mass": 27530.0 }, "refseq": { "ac": "NP_001179078", "name": "transcription initiation factor TFIID subunit 9B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179078" }, "gene_names": [ { "name": "TAF9B", "type": "recommended", "evidence": [ { "id": "A0ABI0P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2" } ] }, { "name": "TAF9B", "type": "synonym", "evidence": [ { "id": "NP_001179078", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179078" } ] } ], "protein_names": [ { "name": "TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa", "type": "synonym", "evidence": [ { "id": "NP_001179078", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179078" } ] }, { "name": "TATA-box binding protein associated factor 9b", "type": "synonym", "evidence": [ { "id": "A0ABI0P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2/entry#names_and_taxonomy" } ] }, { "name": "transcription initiation factor TFIID subunit 9B", "type": "synonym", "evidence": [ { "id": "NP_001179078", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179078" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5S2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TAF9B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2", "locus": { "chromosome": "X", "start_pos": 74256925, "end_pos": 74231999, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000895", "url": "https://www.ensembl.org/id/ENSBTAG00000000895" } ] } } ], "crossref": [ { "id": "ENSBTAG00000000895", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000895", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07979", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07979", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "538983", "url": "https://www.ncbi.nlm.nih.gov/gene/538983", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538983", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538983", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DDNDTMI", "url": "https://omabrowser.org/oma/group/DDNDTMI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MXG0", "url": "https://www.orthodb.org/?gene=A0A3Q1MXG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MWV4", "url": "https://www.orthodb.org/?gene=G3MWV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G5E509", "url": "https://www.orthodb.org/?gene=G5E509", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48068", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48068", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48068:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48068:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02291", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02291", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6804756", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804756", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-73776", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73776", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-73779", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73779", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-75953", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75953", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-76042", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76042", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179078", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179078", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MXG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MXG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5S2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5S2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWV4", "url": "https://www.uniprot.org/uniprotkb/G3MWV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWV4-1", "url": "https://www.uniprot.org/uniprotkb/G3MWV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E509", "url": "https://www.uniprot.org/uniprotkb/G5E509", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E509-1", "url": "https://www.uniprot.org/uniprotkb/G5E509-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTSILDDAKIYSSHAKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSRPTTPNIATPQTASVPNKVAPPVSVTSQRFTVQIPPSQSTPVKPVPATSAVQNVLLNPSMIGPKNILITTNMVSSQNTANESNPLKRKHEDDDDSDTI", "length": 251, "header": "tr|A0ABI0P5S2-1|A0ABI0P5S2_BOVIN Isoform 1 of TATA-box binding protein associated factor 9b OS=Bos taurus OX=9913 GN=TAF9B PE=3 SV=1 CANONICAL=A0ABI0P5S2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MXG0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2/entry#A0A3Q1MXG0-1", "sequence": { "sequence": "MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTSILDDAKIYSSHAKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSRPTTPNIATPQTASVPNKVAPPVSVTSQRFTVQIPPSQSTPVKPGLYLCQAASCQDSYIFLMKATRTSWDREGRWKPDNRKAPQKHCIYQKEEPEGRECS", "length": 253, "header": "tr|A0A3Q1MXG0-1|A0ABI0P5S2_BOVIN Computationally mapped isoform of TATA-box binding protein associated factor 9b OS=Bos taurus OX=9913 GN=TAF9B PE=3 SV=2 CANONICAL=A0ABI0P5S2-1" }, "locus": { "chromosome": "X", "start_pos": 74255921, "end_pos": 74232003, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081359.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081359.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060402.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060402.2" } ] } }, { "isoform_ac": "A0ABI0P5S2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2/entry#A0ABI0P5S2-1", "sequence": { "sequence": "MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTSILDDAKIYSSHAKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSRPTTPNIATPQTASVPNKVAPPVSVTSQRFTVQIPPSQSTPVKPVPATSAVQNVLLNPSMIGPKNILITTNMVSSQNTANESNPLKRKHEDDDDSDTI", "length": 251, "header": "tr|A0ABI0P5S2-1|A0ABI0P5S2_BOVIN Isoform 1 of TATA-box binding protein associated factor 9b OS=Bos taurus OX=9913 GN=TAF9B PE=3 SV=1 CANONICAL=A0ABI0P5S2-1" }, "locus": { "chromosome": "X", "start_pos": 74239260, "end_pos": 74232003, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146974.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146974.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106839.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106839.1" } ] } }, { "isoform_ac": "G3MWV4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2/entry#G3MWV4-1", "sequence": { "sequence": "MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTSILDDAKIYSSHAKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSRPTTPNIATPQTASVPNKVAPPVSVTSQRFTVQIPPSQSTPVKPGTRRKRMLLKDNAGTLHKGKSSCLTSFFIHFELMAGSLQKFQA", "length": 240, "header": "tr|G3MWV4-1|A0ABI0P5S2_BOVIN Computationally mapped isoform of TATA-box binding protein associated factor 9b OS=Bos taurus OX=9913 GN=TAF9B PE=3 SV=2 CANONICAL=A0ABI0P5S2-1" }, "locus": { "chromosome": "X", "start_pos": 74256025, "end_pos": 74232003, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065275.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065275.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054011.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054011.2" } ] } }, { "isoform_ac": "G5E509-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2/entry#G5E509-1", "sequence": { "sequence": "MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTSILDDAKIYSSHAKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIKKVRIFSHFTTPQTASVPNKVAPPVSVTSQRFTVQIPPSQSTPVKPVPATSAVQNVLLNPSMIGPKNILITTNMVSSQNTANESNPLKRKHEDDDDISKPDQWTNL", "length": 239, "header": "tr|G5E509-1|A0ABI0P5S2_BOVIN Computationally mapped isoform of TATA-box binding protein associated factor 9b OS=Bos taurus OX=9913 GN=TAF9B PE=3 SV=2 CANONICAL=A0ABI0P5S2-1" }, "locus": { "chromosome": "X", "start_pos": 74239591, "end_pos": 74232003, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001188.8", "url": "https://www.ensembl.org/id/ENSBTAT00000001188.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001188.6", "url": "https://www.ensembl.org/id/ENSBTAP00000001188.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538983", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538983", "resource": "KEGG Pathway" }, { "id": "R-BTA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" }, { "id": "R-BTA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-BTA-6804756", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6804756", "resource": "Reactome", "description": "Regulation of TP53 Activity through Phosphorylation" }, { "id": "R-BTA-73776", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73776", "resource": "Reactome", "description": "RNA Polymerase II Promoter Escape" }, { "id": "R-BTA-73779", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73779", "resource": "Reactome", "description": "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" }, { "id": "R-BTA-75953", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75953", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation" }, { "id": "R-BTA-76042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-76042", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation And Promoter Clearance" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LFP6-1", "protein_name": "TATA-box binding protein associated factor 9b", "gene_name": "TAF9B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTSILDDAKIYSSHAKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSRPTTPTIATSQTVSVPNKVAPPVSVTSQRFTVQIPPSQSTPVKPVPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANESNPLKRKHEDDDNNDTV", "length": 251 }, "evidence": [ { "id": "A0ABI0P5S2", "url": "https://omabrowser.org/oma/group/A0ABI0P5S2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6NZA9-1", "protein_name": "Transcription initiation factor TFIID subunit 9B", "gene_name": "Taf9b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPAKMAPIKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPTVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLVKKGPNQGRLVPRLSAVSSRPTTPPVAPPQAVSGPNKAATPVSVTSQRFAVQIPPSQSTPAKPAPAATAVQNVLINPSMIGPKNILITTSMVSSQNTATDSNPLKRKHDDDDDNDTM", "length": 249 }, "evidence": [ { "id": "A0ABI0P5S2", "url": "https://omabrowser.org/oma/group/A0ABI0P5S2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HBM6-1", "protein_name": "Transcription initiation factor TFIID subunit 9B", "gene_name": "TAF9B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSKPTTPTIATPQTVSVPNKVATPMSVTSQRFTVQIPPSQSTPVKPVPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEANPLKRKHEDDDDNDIM", "length": 251 }, "evidence": [ { "id": "A0ABI0P5S2", "url": "https://omabrowser.org/oma/group/A0ABI0P5S2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "transcription factor TFTC complex", "id": "GO:0033276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033276", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5S2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2" } ], "pmid": "" }, { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5S2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5S2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5S2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5S2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5S2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5S2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2" } ], "pmid": "" }, { "name": "DNA-templated transcription initiation", "id": "GO:0006352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006352", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5S2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5S2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5S2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5S2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 233, "end_pos": 235 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P696-1", "uniprot_ac": "A0ABI0P696", "uniprot_id": "A0ABI0P696_BOVIN", "mass": { "chemical_mass": 33111.0, "monoisotopic_mass": 33111.0 }, "refseq": { "ac": "XP_059734461", "name": "elongator complex protein 5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059734461" }, "gene_names": [ { "name": "ELP5", "type": "recommended", "evidence": [ { "id": "A0ABI0P696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696" } ] }, { "name": "ELP5", "type": "synonym", "evidence": [ { "id": "XP_059734461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059734461" } ] } ], "protein_names": [ { "name": "Elongator complex protein 5", "type": "recommended", "evidence": [ { "id": "A0ABI0P696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696/entry#names_and_taxonomy" } ] }, { "name": "elongator complex protein 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_059734461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059734461" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P696", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ELP5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696", "locus": { "chromosome": "19", "start_pos": 26969871, "end_pos": 26957720, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019446", "url": "https://www.ensembl.org/id/ENSBTAG00000019446" } ] } } ], "crossref": [ { "id": "ENSBTAG00000019446", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019446", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19496", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19496", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512976", "url": "https://www.ncbi.nlm.nih.gov/gene/512976", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512976", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512976", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DEEIFCI", "url": "https://omabrowser.org/oma/group/DEEIFCI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR15641", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15641", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15641:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15641:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10483", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10483", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059734461", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059734461", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LI00", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LI00-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRU1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S399", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S399", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S399-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S399-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SI13", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SI13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SI13-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SI13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SK03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SK03-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZP1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZP1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0U0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0U0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0U0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P696", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P696-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QWY1", "url": "https://www.uniprot.org/uniprotkb/F6QWY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QWY1-1", "url": "https://www.uniprot.org/uniprotkb/F6QWY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLESLLALGGLVLLRDSVEWEGRSLLKALVKKSALCGEQVHVLGCEVSEEEFREGFDSSINNRLVYHDLFRDPLSWSKPGKALPGGPLEALRALDKRTGSGPATIALDSLSWLLHHLPCPILCQTLHALSRQDSCPGDTLPGEQVRVLGLLHEELHGPGPLGALSSLAQTEVTLSGTMGQASAHILYRRPRQRPTLQTQWFSILPDFSLELQVEPLLESQPPSDLHTPSVDPTTHLTFNLHLSKKEREAKDSLTLPFQFSSEKQQALLRPGLGQATSHIFYEPDAYDDLDQEDPDDDLDV", "length": 300, "header": "tr|A0ABI0P696-1|A0ABI0P696_BOVIN Isoform 1 of Elongator complex protein 5 OS=Bos taurus OX=9913 GN=ELP5 PE=3 SV=1 CANONICAL=A0ABI0P696-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LI00-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696/entry#A0A3Q1LI00-1", "sequence": { "sequence": "MLESLLALGGLVLLRDSVEWEGRSLLKALVKKSALCGEQVHVLGCEVSEEEFREGFDSSINNRLVYHDLFRDPLSWSKPGKALPGGPLEALRALDKRTGSGPATIALDSLSWLLHHLPCPILCQTLHALSRQDSCPGDTLPGEQVRVLGLLHEELHGPGPLGALSSLAQTEVTLSGTMGQASAHILYRRPRQRPTLQTQWFSILPDFSLELQVEPLLESQPPSDLHTPSTAGSTAPW", "length": 237, "header": "tr|A0A3Q1LI00-1|A0ABI0P696_BOVIN Computationally mapped isoform of Elongator complex protein 5 OS=Bos taurus OX=9913 GN=ELP5 PE=3 SV=2 CANONICAL=A0ABI0P696-1" }, "locus": { "chromosome": "19", "start_pos": 26969513, "end_pos": 26964197, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068270.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068270.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058514.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058514.2" } ] } }, { "isoform_ac": "A0A3Q1LRU1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696/entry#A0A3Q1LRU1-1", "sequence": { "sequence": "GAARGKGAGGGSGARRAAEAVANGPDSVEWEGRSLLKALVKKSALCGEQVHVLGCEVSEEEFREGFDSSINNRLVYHDLFRDPLSWSKPGKALPGGPLEALRALDKRTGSGPATIALDSLSWLLHHLPCPILCQTLHALSRQDSCPGDTLPGEQVRVLGLLHEELHGPGPLGALSSLAQTEVTLSGTMGQASAHILYRRPRQRPTLQTQWFSILPDFSLELQVEPLLESQPPSDLHTPSVDPTTHLTFNLHLSKKEREAKDSLTLPFQFSSEKQQALLRPGLGQATSHIFYEPDAYDDLDQEDPDDDLDV", "length": 310, "header": "tr|A0A3Q1LRU1-1|A0ABI0P696_BOVIN Computationally mapped isoform of Elongator complex protein 5 OS=Bos taurus OX=9913 GN=ELP5 PE=3 SV=2 CANONICAL=A0ABI0P696-1" }, "locus": { "chromosome": "19", "start_pos": 26969601, "end_pos": 26963390, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083778.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083778.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057786.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057786.2" } ] } }, { "isoform_ac": "A0AAA9S399-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696/entry#A0AAA9S399-1", "sequence": { "sequence": "MLESLLALGGLVLLRDSVEWEGRSLLKALVKKSALCGEQVHVLGCEVSEEEFREGFDSSINNRLVYHDLFRDPLSWSKPGKALPGGPLEALRALDKRTGSGPATIALDSLSWLLHHLPCPILCQTLHALSRQDSCPGEAPHLFLPLIYTLPTVPLSTLTRN", "length": 161, "header": "tr|A0AAA9S399-1|A0ABI0P696_BOVIN Computationally mapped isoform of Elongator complex protein 5 OS=Bos taurus OX=9913 GN=ELP5 PE=3 SV=1 CANONICAL=A0ABI0P696-1" }, "locus": { "chromosome": "19", "start_pos": 26966909, "end_pos": 26964197, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133016.2", "url": "https://www.ensembl.org/id/ENSBTAT00000133016.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078239.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078239.1" } ] } }, { "isoform_ac": "A0AAA9SI13-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696/entry#A0AAA9SI13-1", "sequence": { "sequence": "RSPPPPAPTQGSPCGSASSKDSVEWEGRSLLKALVKKSALCGEQVHVLGCEVSEEEFREGFDSSINNRLVYHDLFRDPLSWSKPGKALPGGPLEALRALDKRTGSGPATIALDSLSWLLHHLPCPILCQTLHALSRQDSCPGDTLPGEQVRVLGLLHEELHGPGPLGALSSLAQTEVTLSGTMGQASAHILYRRPRQRPTLQTQWFSILPDFSLELQVEPLLESQPPSDLHTPSVDPTTHLTFNLHLSKKEREAKDSLTLPFQFSSEKQQALLRPGLGQATSHIFYEPDAYDDLDQEDPDDDLDV", "length": 305, "header": "tr|A0AAA9SI13-1|A0ABI0P696_BOVIN Computationally mapped isoform of Elongator complex protein 5 OS=Bos taurus OX=9913 GN=ELP5 PE=3 SV=1 CANONICAL=A0ABI0P696-1" }, "locus": { "chromosome": "19", "start_pos": 26969601, "end_pos": 26957948, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113251.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113251.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082173.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082173.1" } ] } }, { "isoform_ac": "A0AAA9SK03-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696/entry#A0AAA9SK03-1", "sequence": { "sequence": "RAVSGRSPPPPAPTQGSPCGSASSKDSVEWEGRSLLKALVKKSALCGEQVHVLGCEVSEEEFREGFDSSINNRLVYHDLFRDPLSWSKPGKALPGGPLEALRALDKRTGSGPATIALDSLSWLLHHLPCPILCQTLHALSRQDSCPGDTLPGEQVRVLGLLHEELHGPGPLGALSSLAQTEVTLSGTMGQASAHILYRRPRQRPTLQTQWFSILPDFSLELQVEPLLESQPPSDLHTPSVDPTTHLTFNLHLSKKEREAKDSLTLPFQFSSEKQQALLRPGLGQATSHIFYEPDAYDDLDQEDPDDDLDV", "length": 310, "header": "tr|A0AAA9SK03-1|A0ABI0P696_BOVIN Computationally mapped isoform of Elongator complex protein 5 OS=Bos taurus OX=9913 GN=ELP5 PE=3 SV=1 CANONICAL=A0ABI0P696-1" }, "locus": { "chromosome": "19", "start_pos": 26969601, "end_pos": 26961080, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115343.2", "url": "https://www.ensembl.org/id/ENSBTAT00000115343.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085642.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085642.1" } ] } }, { "isoform_ac": "A0AAA9TZP1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696/entry#A0AAA9TZP1-1", "sequence": { "sequence": "RHLSPRLTPSEGLARPPPPPTDNCPNGSFRPSHGKIVERGVVPTCVYQHSRGTIPREPSWDSVEWEGRSLLKALVKKSALCGEQVHVLGCEVSEEEFREGFDSSINNRLVYHDLFRDPLSWSKPGKALPGGPLEALRALDKRTGSGPATIALDSLSWLLHHLPCPILCQTLHALSRQDSCPGDTLPGEQVRVLGLLHEELHGPGPLGALSSLAQTEVTLSGTMGQASAHILYRRPRQRPTLQTQWFSILPDFSLELQVEPLLESQPPSDLHTPSVDPTTHLTFNLHLSKKEREAKDSLTLPFQFSSEKQQALLRPGLGQATSHIFYEPDAYDDLDQEDPDDDLDV", "length": 345, "header": "tr|A0AAA9TZP1-1|A0ABI0P696_BOVIN Computationally mapped isoform of Elongator complex protein 5 OS=Bos taurus OX=9913 GN=ELP5 PE=3 SV=1 CANONICAL=A0ABI0P696-1" }, "locus": { "chromosome": "19", "start_pos": 26969601, "end_pos": 26963862, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125603.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125603.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103049.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103049.1" } ] } }, { "isoform_ac": "A0ABI0P0U0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696/entry#A0ABI0P0U0-1", "sequence": { "sequence": "GSGARRAAEAVANGPDSVEWEGRSLLKALVKKSALCGEQVHVLGCEVSEEEFREGFDSSINNRSILYHLSHQRSLKPSRQFIEWKWVFQRRLVYHDLFRDPLSWSKPGKALPGGPLEALRALDKRTGSGPATIALDSLSWLLHHLPCPILCQTLHALSRQDSCPGDTLPGEQVRVLGLLHEELHGPGPLGALSSLAQTEVTLSGTMGQASAHILYRRPRQRPTLQTQWFSILPDFSLELQVEPLLESQPPSDLHTPSVDPTTHLTFNLHLSKKEREAKDSLTLPFQFSSEKQQALLRPGLGQATSHIFYEPDAYDDLDQEDPDDDLDV", "length": 328, "header": "tr|A0ABI0P0U0-1|A0ABI0P696_BOVIN Computationally mapped isoform of Elongator complex protein 5 OS=Bos taurus OX=9913 GN=ELP5 PE=3 SV=1 CANONICAL=A0ABI0P696-1" }, "locus": { "chromosome": "19", "start_pos": 26969601, "end_pos": 26963420, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144636.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144636.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106511.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106511.1" } ] } }, { "isoform_ac": "A0ABI0P696-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696/entry#A0ABI0P696-1", "sequence": { "sequence": "MLESLLALGGLVLLRDSVEWEGRSLLKALVKKSALCGEQVHVLGCEVSEEEFREGFDSSINNRLVYHDLFRDPLSWSKPGKALPGGPLEALRALDKRTGSGPATIALDSLSWLLHHLPCPILCQTLHALSRQDSCPGDTLPGEQVRVLGLLHEELHGPGPLGALSSLAQTEVTLSGTMGQASAHILYRRPRQRPTLQTQWFSILPDFSLELQVEPLLESQPPSDLHTPSVDPTTHLTFNLHLSKKEREAKDSLTLPFQFSSEKQQALLRPGLGQATSHIFYEPDAYDDLDQEDPDDDLDV", "length": 300, "header": "tr|A0ABI0P696-1|A0ABI0P696_BOVIN Isoform 1 of Elongator complex protein 5 OS=Bos taurus OX=9913 GN=ELP5 PE=3 SV=1 CANONICAL=A0ABI0P696-1" }, "locus": { "chromosome": "19", "start_pos": 26969601, "end_pos": 26964197, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148613.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148613.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107110.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107110.1" } ] } }, { "isoform_ac": "F6QWY1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696/entry#F6QWY1-1", "sequence": { "sequence": "MDLLPSNRSPPPPAPTQGSPCGSASSKDSVEWEGRSLLKALVKKSALCGEQVHVLGCEVSEEEFREGFDSSINNRLVYHDLFRDPLSWSKPGKALPGGPLEALRALDKRTGSGPATIALDSLSWLLHHLPCPILCQTLHALSRQDSCPGDTLPGEQVRVLGLLHEELHGPGPLGALSSLAQTEVTLSGTMGQASAHILYRRPRQRPTLQTQWFSILPDFSLELQVEPLLESQPPSDLHTPSVDPTTHLTFNLHLSKKEREAKDSLTLPFQFSSEKQQALLRPGLGQATSHIFYEPDAYDDLDQEDPDDDLDV", "length": 312, "header": "tr|F6QWY1-1|A0ABI0P696_BOVIN Computationally mapped isoform of Elongator complex protein 5 OS=Bos taurus OX=9913 GN=ELP5 PE=3 SV=3 CANONICAL=A0ABI0P696-1" }, "locus": { "chromosome": "19", "start_pos": 26969601, "end_pos": 26962514, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025904.7", "url": "https://www.ensembl.org/id/ENSBTAT00000025904.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025904.6", "url": "https://www.ensembl.org/id/ENSBTAP00000025904.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:512976", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512976", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3GY98-1", "protein_name": "Elongator complex protein 5", "gene_name": "Elp5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLDSLLAVGGLVLLRDSVECEGRSLLKALIKKSALRGEQIHVLGCEVSEEEFREGFGPDINSRVVYHDLFKDPLNWSKSGEAVPEGPLGTLRTLCRRTDPGPVTIALDSVSWLLFHLPCITLCKTLHALSQPSVSSGADSLVDQVRVLGLLHEELHGPGPMGALSTLAQTEVTVSGKMGQTSASILYRRPQQRATYQTWWFSILPDLSVDLREKLPLHSELHPDPHTTQVDPTTDLTFNLHLSKKEREARDSLTLPFQFSSEKQQALLRRGPGQTTSHIFYEPDAFDDVDQEDPDDDLDI", "length": 300 }, "evidence": [ { "id": "A0ABI0P696", "url": "https://omabrowser.org/oma/group/A0ABI0P696/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8TE02-5", "protein_name": "Elongator complex protein 5", "gene_name": "ELP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLDSLLALGGLVLLRDSVEWEGRSLLKALVKKSALCGEQVHILGCEVSEEEFREGFDSDINNRLVYHDFFRDPLNWSKTEEAFPGGPLGALRAMCKRTDPVPVTIALDSLSWLLLRLPCTTLCQVLHAVSHQDSCPGDSSSVGKVSVLGLLHEELHGPGPVGALSSLAQTEVTLGGTMGQASAHILCRRPRQRPTDQTQWFSILPDFSLDLQEGPSVESQPYSDPHIPPVDPTTHLTFNLHLSKKEREARDSLILPFQFSSEKQQALLRPRPGQATSHIFYEPDAYDDLDQEDPDDDLDI", "length": 300 }, "evidence": [ { "id": "A0ABI0P696", "url": "https://omabrowser.org/oma/group/A0ABI0P696/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99L85-1", "protein_name": "Elongator complex protein 5", "gene_name": "Elp5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLDSLLAIGGLVLLRDSVEWEGRSLLKALIKKSALRGEQVHVLGCEVSEEEFREGFDSDVNSRLVYHDLFRDPLNWSKPGEAVPEGPLKALRSMCKRTDHGSVTIALDSLSWLLCHIPCVTLCQALHALSQQNGDPGDNSLVEQVRVLGLLHEELHGPGSMGALNTLAHTEVTLSGKVDQTSASILCRRPQQRATYQTWWFSVLPDFSLTLHEGLPLRSELHPDHHTTQVDPTAHLTFNLHLSKKEREARDSLTLPFQFSSEKQKALLHPVPSRTTGHIFYEPDAFDDVDPEDPDDDLDI", "length": 300 }, "evidence": [ { "id": "A0ABI0P696", "url": "https://omabrowser.org/oma/group/A0ABI0P696/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P696", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P696", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696" } ], "pmid": "" }, { "name": "elongator holoenzyme complex", "id": "GO:0033588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033588", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P696", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P696", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P696", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P696", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P696", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696" } ], "pmid": "" }, { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P696", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P696" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P6X4-1", "uniprot_ac": "A0ABI0P6X4", "uniprot_id": "A0ABI0P6X4_BOVIN", "mass": { "chemical_mass": 35611.0, "monoisotopic_mass": 35611.0 }, "refseq": {}, "gene_names": [ { "name": "MAPRE1", "type": "recommended", "evidence": [ { "id": "A0ABI0P6X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6X4" } ] } ], "protein_names": [ { "name": "Microtubule-associated protein RP/EB family member 1", "type": "recommended", "evidence": [ { "id": "A0ABI0P6X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6X4/entry#names_and_taxonomy" } ] }, { "name": "APC-binding protein EB1", "type": "synonym", "evidence": [ 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{ "uniprot_canonical_ac": "A0ABI0P5M9-1", "uniprot_ac": "A0ABI0P5M9", "uniprot_id": "A0ABI0P5M9_BOVIN", "mass": { "chemical_mass": 59571.0, "monoisotopic_mass": 59571.0 }, "refseq": {}, "gene_names": [ { "name": "HDAC11", "type": "recommended", "evidence": [ { "id": "A0ABI0P5M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9" } ] } ], "protein_names": [ { "name": "Histone deacetylase 11", "type": "recommended", "evidence": [ { "id": "A0ABI0P5M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9/entry#names_and_taxonomy" } ] }, { "name": "3.5.1.98", "type": "synonym", "evidence": [ { "id": "A0ABI0P5M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). 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"database": "Ensembl Gene", "id": "ENSBTAG00000007208", "url": "https://www.ensembl.org/id/ENSBTAG00000007208" } ] } } ], "crossref": [ { "id": "ENSBTAG00000007208", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007208", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09993", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09993", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LMH8", "url": "https://www.orthodb.org/?gene=A0A3Q1LMH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MWX4", "url": "https://www.orthodb.org/?gene=F1MWX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10625", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10625", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10625:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10625:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00850", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00850", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-350054", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-350054", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "58196", "url": "https://www.rhea-db.org/rhea/58196", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LMH8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S161", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S161", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S161-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S161-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQE6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQE6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ00", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ00-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5M9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P734", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P734", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P734-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P734-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MWX4", "url": "https://www.uniprot.org/uniprotkb/F1MWX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MWX4-1", "url": "https://www.uniprot.org/uniprotkb/F1MWX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFACGRRDLELEERWGRGLRPRRRRARRGTPTLCDAGPSRGGAGPSLSSSAPSGGGRGRGRVLGGPAPRPARSRSGGCAGRARPRDVSAAGAGARAGAPARPRGFPGVPAGGRTGARAAGRARQVRAQVRRAVGPLGPGQRPAYSGQPSATNLRHTGRWPGGGPRHARLGVFPRGPPAERRPLRWQAGSLCPVRRLRRPHPTQLYQHVPDSRWPIVYSPRYNITFLGLEKLHPFDAGKWGKVISLLKEEKLLSDSMLVEAREASDEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVDRGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFDRVEGISKATIVDLDAHQGNGHERDFMGDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLQKVERNLEKALQEHRPDIVVYNAGTDILEGDRLGGLAISPQGVVKRDELVFRIVRGRQLPILMVTSGGYQKRTARIIADSILNLYSLGLIGPESASVSAQNSDTPLLPPEVP", "length": 544, "header": "tr|A0ABI0P5M9-1|A0ABI0P5M9_BOVIN Isoform 1 of Histone deacetylase 11 OS=Bos taurus OX=9913 GN=HDAC11 PE=3 SV=1 CANONICAL=A0ABI0P5M9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMH8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9/entry#A0A3Q1LMH8-1", "sequence": { "sequence": "MGLEKLHPFDAGKWGKVISLLKEEKLLSDSMLVEAREASDEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAAASTTAPATGAGASAPTRTSHLPSSSCLTEWRASPKPPSWTSTPIRATGTSATSWATSACTSWTCTTATSTPGTASPSRPSGGRWSWSGARRMTSTCRRWRGTWRKPCRSTAPTSWCTTRARTSSRGTASAGWPSVRRVS", "length": 236, "header": "tr|A0A3Q1LMH8-1|A0ABI0P5M9_BOVIN Computationally mapped isoform of Histone deacetylase 11 OS=Bos taurus OX=9913 GN=HDAC11 PE=3 SV=2 CANONICAL=A0ABI0P5M9-1" }, "locus": { "chromosome": "22", "start_pos": 58440674, "end_pos": 58429100, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070147.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070147.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058070.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058070.2" } ] } }, { "isoform_ac": "A0AAA9S161-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9/entry#A0AAA9S161-1", "sequence": { "sequence": "MPHPTQLYQHVPDSRWPIVYSPRYNITFLGLEKLHPFDAGKWGKVISLLKEAIRRKVELEWGTEDDEYLQKVERNLEKALQEHRPDIVVYNAGTDILEGDRLGGLAISPQGVVKRDELVFRIVRGRQLPILMVTSGGYQKRTARIIADSILNLYSLGLIGPESASVSAQNSDTPLLPPEVP", "length": 181, "header": "tr|A0AAA9S161-1|A0ABI0P5M9_BOVIN Computationally mapped isoform of Histone deacetylase 11 OS=Bos taurus OX=9913 GN=HDAC11 PE=3 SV=1 CANONICAL=A0ABI0P5M9-1" }, "locus": { "chromosome": "22", "start_pos": 58441725, "end_pos": 58428894, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095149.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095149.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077399.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077399.1" } ] } }, { "isoform_ac": "A0AAA9TQE6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9/entry#A0AAA9TQE6-1", "sequence": { "sequence": "MPHPTQLYQHVPDSRWPIVYSPRYNITFLGLEKLHPFDAGKWGKVISLLKEEKLLSDSMLVEAREASDEDLLVVHTRRYLNELKGNGHERDFMGDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLQKVERNLEKALQEHRPDIVVYNAGTDILEGDRLGGLAISPQGVVKRDELVFRIVRGRQLPILMVTSGGYQKRTARIIADSILNLYSLGLIGPESASVSAQNSDTPLLPPEVP", "length": 247, "header": "tr|A0AAA9TQE6-1|A0ABI0P5M9_BOVIN Computationally mapped isoform of Histone deacetylase 11 OS=Bos taurus OX=9913 GN=HDAC11 PE=3 SV=1 CANONICAL=A0ABI0P5M9-1" }, "locus": { "chromosome": "22", "start_pos": 58441725, "end_pos": 58428894, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128713.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128713.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100810.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100810.1" } ] } }, { "isoform_ac": "A0ABI0NQ00-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9/entry#A0ABI0NQ00-1", "sequence": { "sequence": "PHPTQLYQHVPDSRWPIVYSPRYNITFLGLEKLHPFDAGKWGKVISLLKEEKLLSDSMLVEAREASDEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVDRGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFDRVEGISKATIVDLDAHQGNGHERDFMGDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLQKVERNLEKALQEHRPDIVVYNAGTDILEGDRLGGLAISPQGVVKRDELVFRIVRGRQLPILMVTSGGYQKRTARIIADSILNLYSLGLIGPESASVSAQNSDTPLLPPHPPVSAPNTPSPSTRACDPRGQAAMGLCRGASVPENHKGPSQ", "length": 385, "header": "tr|A0ABI0NQ00-1|A0ABI0P5M9_BOVIN Computationally mapped isoform of Histone deacetylase 11 OS=Bos taurus OX=9913 GN=HDAC11 PE=3 SV=1 CANONICAL=A0ABI0P5M9-1" }, "locus": { "chromosome": "22", "start_pos": 58440755, "end_pos": 58427523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141818.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141818.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104211.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104211.1" } ] } }, { "isoform_ac": "A0ABI0P5M9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9/entry#A0ABI0P5M9-1", "sequence": { "sequence": "MFACGRRDLELEERWGRGLRPRRRRARRGTPTLCDAGPSRGGAGPSLSSSAPSGGGRGRGRVLGGPAPRPARSRSGGCAGRARPRDVSAAGAGARAGAPARPRGFPGVPAGGRTGARAAGRARQVRAQVRRAVGPLGPGQRPAYSGQPSATNLRHTGRWPGGGPRHARLGVFPRGPPAERRPLRWQAGSLCPVRRLRRPHPTQLYQHVPDSRWPIVYSPRYNITFLGLEKLHPFDAGKWGKVISLLKEEKLLSDSMLVEAREASDEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVDRGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFDRVEGISKATIVDLDAHQGNGHERDFMGDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLQKVERNLEKALQEHRPDIVVYNAGTDILEGDRLGGLAISPQGVVKRDELVFRIVRGRQLPILMVTSGGYQKRTARIIADSILNLYSLGLIGPESASVSAQNSDTPLLPPEVP", "length": 544, "header": "tr|A0ABI0P5M9-1|A0ABI0P5M9_BOVIN Isoform 1 of Histone deacetylase 11 OS=Bos taurus OX=9913 GN=HDAC11 PE=3 SV=1 CANONICAL=A0ABI0P5M9-1" }, "locus": { "chromosome": "22", "start_pos": 58441981, "end_pos": 58428894, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150975.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150975.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106236.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106236.1" } ] } }, { "isoform_ac": "A0ABI0P734-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9/entry#A0ABI0P734-1", "sequence": { "sequence": "MPHPTQLYQHVPDSRWPIVYSPRYNITFLGLEKLHPFDAGKWGKVISLLKEEKLLSDSMLVEAREASDEDLLVVHTRRYLNELKRPSGGRWSWSGARRMTSTCRRWRGTWRKPCRSTAPTSWCTTRARTSSRGTASAGWPSVRRVS", "length": 146, "header": "tr|A0ABI0P734-1|A0ABI0P734_BOVIN Computationally mapped isoform of Histone deacetylase 11 OS=Bos taurus OX=9913 GN=HDAC11 PE=4 SV=1 CANONICAL=A0ABI0P5M9-1" }, "locus": { "chromosome": "22", "start_pos": 58441725, "end_pos": 58429100, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153528.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153528.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106929.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106929.1" } ] } }, { "isoform_ac": "F1MWX4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9/entry#F1MWX4-1", "sequence": { "sequence": "MPHPTQLYQHVPDSRWPIVYSPRYNITFLGLEKLHPFDAGKWGKVISLLKEEKLLSDSMLVEAREASDEDLLVVHTRRYLNELKFLFDRVEGISKATIVDLDAHQGNGHERDFMGDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLQKVERNLEKALQEHRPDIVVYNAGTDILEGDRLGGLAISPQGVVKRDELVFRIVRGRQLPILMVTSGGYQKRTARIIADSILNLYSLGLIGPESASVSAQNSDTPLLPPEVP", "length": 268, "header": "tr|F1MWX4-1|A0ABI0P5M9_BOVIN Computationally mapped isoform of Histone deacetylase 11 OS=Bos taurus OX=9913 GN=HDAC11 PE=3 SV=4 CANONICAL=A0ABI0P5M9-1" }, "locus": { "chromosome": "22", "start_pos": 58441725, "end_pos": 58428894, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009482.7", "url": "https://www.ensembl.org/id/ENSBTAT00000009482.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009482.7", "url": "https://www.ensembl.org/id/ENSBTAP00000009482.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-350054", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-350054", "resource": "Reactome", "description": "Notch-HLH transcription pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9" } ], "pmid": "" }, { "name": "histone deacetylase activity", "id": "GO:0004407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004407", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "58196", "name": "", "equation": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9U2N9-1", "A0A3Q1NHU6-1", "F1MYR0-1", "A0A3Q1MDJ2-1", "F1N0W0-1", "Q32PJ8-1", "Q0VCB2-1", "A0AAA9SG42-1", "A0ABI0P5M9-1" ], "evidence": [ { "id": "58196", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/58196" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MDJ2", "gene_name": "HDAC8", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "A0A3Q1MDJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDJ2" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "A0A3Q1MDJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDJ2" } ] } ] }, { "uniprot_ac": "A0A3Q1NHU6", "gene_name": "HDAC9", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "A0A3Q1NHU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NHU6" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "A0A3Q1NHU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NHU6" } ] } ] }, { "uniprot_ac": "A0AAA9SG42", "gene_name": "HDAC5", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "A0AAA9SG42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG42" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "A0AAA9SG42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG42" } ] } ] }, { "uniprot_ac": "A0AAA9U2N9", "gene_name": "HDAC7", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "A0AAA9U2N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U2N9" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "A0AAA9U2N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U2N9" } ] } ] }, { "uniprot_ac": "A0ABI0P5M9", "gene_name": "HDAC11", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "A0ABI0P5M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "A0ABI0P5M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9" } ] } ] }, { "uniprot_ac": "F1MYR0", "gene_name": "HDAC4", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "F1MYR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYR0" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "F1MYR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYR0" } ] } ] }, { "uniprot_ac": "F1N0W0", "gene_name": "HDAC3", "activity": [ { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "F1N0W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0W0" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "F1N0W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0W0" } ] } ] }, { "uniprot_ac": "Q0VCB2", "gene_name": "HDAC8", "activity": [ { "ec_number": "3.5.1.-", "activity": "", "evidence": [ { "id": "Q0VCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCB2" } ] }, { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "Q0VCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCB2" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "Q0VCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VCB2" } ] } ] }, { "uniprot_ac": "Q32PJ8", "gene_name": "HDAC1", "activity": [ { "ec_number": "3.5.1.-", "activity": "", "evidence": [ { "id": "Q32PJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PJ8" } ] }, { "ec_number": "3.5.1.98", "activity": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "Q32PJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PJ8" } ] }, { "ec_number": "3.5.1.98", "activity": "", "evidence": [ { "id": "Q32PJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PJ8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P5M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M9" }, { "id": "PF00850", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Histone deacetylase", "eco_id": "ECO_0000259", "start_pos": 232, "end_pos": 513, "start_aa": "His", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.1.98", "ec_name": "N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate.", "evidence": [ { "id": "3.5.1.98", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.98" }, { "id": "3.5.1.98", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.1.98" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { 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"uniprot_ac": "A0ABZ3NNR8", "uniprot_id": "A0ABZ3NNR8_BOVIN", "mass": { "chemical_mass": 35593.0, "monoisotopic_mass": 35593.0 }, "refseq": {}, "gene_names": [ { "name": "PLEKHB1", "type": "recommended", "evidence": [ { "id": "A0ABZ3NNR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNR8" } ] } ], "protein_names": [ { "name": "Pleckstrin homology domain containing B1", "type": "synonym", "evidence": [ { "id": "A0ABZ3NNR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNR8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNR8", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNR8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PLEKHB1", "url": 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[ "Protein Classification" ] }, { "id": "IPR039680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HFNVRDV", "url": "https://omabrowser.org/oma/group/HFNVRDV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LNA2", "url": "https://www.orthodb.org/?gene=A0A3Q1LNA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MY34", "url": "https://www.orthodb.org/?gene=G3MY34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MZT0", "url": "https://www.orthodb.org/?gene=G3MZT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14309", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14309", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14309:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14309:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LNA2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU36", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU36-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABZ3NNR8", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABZ3NNR8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY34", "url": "https://www.uniprot.org/uniprotkb/G3MY34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY34-1", "url": "https://www.uniprot.org/uniprotkb/G3MY34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZT0", "url": "https://www.uniprot.org/uniprotkb/G3MZT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZT0-1", "url": "https://www.uniprot.org/uniprotkb/G3MZT0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTCYPRTEGQIGDPPVSLGSGLERKDDFLWELCAPFCHPRRFPLGSAFLIPLSPRLLGICPPAGAFWKCCSDGPGTMSPAAPVPPDSTLESPFEEMALVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVLIHFNVRDIKIGQECHDVQPPEGRSRDGLLTVNLREGSRLHLCAETRDDAIAWKTALLEANSTPAPAGATVPPRSRRVCPKVRCVTRSWSPCKVERRIWVRVYSPYQDYYEVVPPNAHETTYVRSYYGPPYVGPGVTHVVVREDPCYSAGAPLAMGMLAGAATGAALGSLMWSPCWF", "length": 319, "header": "tr|A0ABZ3NNR8-1|A0ABZ3NNR8_BOVIN Isoform 1 of Pleckstrin homology domain containing B1 OS=Bos taurus OX=9913 GN=PLEKHB1 PE=4 SV=1 CANONICAL=A0ABZ3NNR8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LNA2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNR8/entry#A0A3Q1LNA2-1", "sequence": { "sequence": "MALVRGGWLWRQNVQPPEGRSRDGLLTVNLREGSRLHLCAETRDDAIAWKTALLEANSTPVRVYSPYQDYYEVVPPNAHETTYVRSYYGPPYVGPGVTHVVVREDPCYSAGAPLAMGMLAGAATGAALGSLMWSPCWF", "length": 138, "header": "tr|A0A3Q1LNA2-1|A0ABZ3NNR8_BOVIN Computationally mapped isoform of Pleckstrin homology domain containing B1 OS=Bos taurus OX=9913 GN=PLEKHB1 PE=4 SV=2 CANONICAL=A0ABZ3NNR8-1" }, "locus": { "chromosome": "15", "start_pos": 53135241, "end_pos": 53124149, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079735.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079735.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058439.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058439.2" } ] } }, { "isoform_ac": "A0AAA9TU36-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNR8/entry#A0AAA9TU36-1", "sequence": { "sequence": "MGGSGQRSRDKAGPSTPGVPASPCATQQQVPPDSTLESPFEEMALVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVLIHFNVRDIKIGQECHDVQPPEGRSRDGLLTVNLREGSRLHLCAETRDDAIAWKTALLEANSTPAPAGATVPPRSRRVCPKVRCVTRSWSPCKVERRIWVRVYSPYQDYYEVVPPNAHETTYVRSYYGPPYVGPGVTHVVVREDPCYSAGAPLAMGMLAGAATGAALGSLMWSPCWF", "length": 266, "header": "tr|A0AAA9TU36-1|A0ABZ3NNR8_BOVIN Computationally mapped isoform of Pleckstrin homology domain containing B1 OS=Bos taurus OX=9913 GN=PLEKHB1 PE=4 SV=1 CANONICAL=A0ABZ3NNR8-1" }, "locus": { "chromosome": "15", "start_pos": 53135241, "end_pos": 53122897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104840.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104840.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102109.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102109.1" } ] } }, { "isoform_ac": "A0ABZ3NNR8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNR8/entry#A0ABZ3NNR8-1", "sequence": { "sequence": "MTCYPRTEGQIGDPPVSLGSGLERKDDFLWELCAPFCHPRRFPLGSAFLIPLSPRLLGICPPAGAFWKCCSDGPGTMSPAAPVPPDSTLESPFEEMALVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVLIHFNVRDIKIGQECHDVQPPEGRSRDGLLTVNLREGSRLHLCAETRDDAIAWKTALLEANSTPAPAGATVPPRSRRVCPKVRCVTRSWSPCKVERRIWVRVYSPYQDYYEVVPPNAHETTYVRSYYGPPYVGPGVTHVVVREDPCYSAGAPLAMGMLAGAATGAALGSLMWSPCWF", "length": 319, "header": "tr|A0ABZ3NNR8-1|A0ABZ3NNR8_BOVIN Isoform 1 of Pleckstrin homology domain containing B1 OS=Bos taurus OX=9913 GN=PLEKHB1 PE=4 SV=1 CANONICAL=A0ABZ3NNR8-1" }, "locus": { "chromosome": "15", "start_pos": 53135241, "end_pos": 53117280, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012961.7", "url": "https://www.ensembl.org/id/ENSBTAT00000012961.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012961.6", "url": "https://www.ensembl.org/id/ENSBTAP00000012961.6" } ] } }, { "isoform_ac": "G3MY34-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNR8/entry#G3MY34-1", "sequence": { "sequence": "MSPAAPVPPDSTLESPFEEMALVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVLIHFNVRDIKIGQECHDVQPPEGRSRDGLLTVNLREGSRLHLCAETRDDAIAWKTALLEANSTPAPAGATVPPRSRRVCPKVRCVTRSWSPCKVERRIWVRVYSPYQDYYEVVPPNAHETTYVRSYYGPPYVGPGVTHVVVREDPCYSAGAPLAMGMLAGAATGAALGSLMWSPCWF", "length": 243, "header": "tr|G3MY34-1|A0ABZ3NNR8_BOVIN Computationally mapped isoform of Pleckstrin homology domain containing B1 OS=Bos taurus OX=9913 GN=PLEKHB1 PE=4 SV=1 CANONICAL=A0ABZ3NNR8-1" }, "locus": { "chromosome": "15", "start_pos": 53135241, "end_pos": 53117509, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065185.2", "url": "https://www.ensembl.org/id/ENSBTAT00000065185.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054461.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054461.1" } ] } }, { "isoform_ac": "G3MZT0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNR8/entry#G3MZT0-1", "sequence": { "sequence": "MTCYPRTEGQIGDPPVSLGSGLERKDDFLWELCAPFCHPRRFPLGSAFLIPLSPRLLGICPPAGAFWKCCSDGPGTMSPAAPVPPDSTLESPFEEMALVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVLIHFNVRDIKIGQECHDVQPPEGRSRDGLLTVNLREGSRLHLCAETRDDAIAWKTALLEANSTPVRVYSPYQDYYEVVPPNAHETTYVRSYYGPPYVGPGVTHVVVREDPCYSAGAPLAMGMLAGAATGAALGSLMWSPCWF", "length": 284, "header": "tr|G3MZT0-1|A0ABZ3NNR8_BOVIN Computationally mapped isoform of Pleckstrin homology domain containing B1 OS=Bos taurus OX=9913 GN=PLEKHB1 PE=4 SV=3 CANONICAL=A0ABZ3NNR8-1" }, "locus": { "chromosome": "15", "start_pos": 53135241, "end_pos": 53117280, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065711.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065711.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055083.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055083.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FN91-1", "protein_name": "Pleckstrin homology domain-containing family B member 1 isoform X1", "gene_name": "Plekhb1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVLIHFNVRDIKVGQECHDVQPPEGRSRDGLLTVNLREGSRLHLCAETRDDAIAWKTALMEANSTPAPAGATVPPRSRRVCPKVRCTTLSWKPCKVERRIWVRVYSPYQDYYEVVPPNAHEATYVRSYYGPPYAGPGVTHVIVREDPCYSAGAPLAMGMLAGAATGAALGSLMWSPCWF", "length": 224 }, "evidence": [ { "id": "A0ABZ3NNR8", "url": "https://omabrowser.org/oma/group/A0ABZ3NNR8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SUT1-1", "protein_name": "Pleckstrin homology domain containing B1", "gene_name": "PLEKHB1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVLIHFNVRDIKIGQECHDVQPPEGRSRDGLLTVNLREGTRLHLCAETRDDALAWKTALLEANSTPAPAGATVPPRSRRVCPKVRCVTRSWSPCKVERRIWVRVYSPYQDYYEVVPPNAHEATYVRSYYGPPYAGPGVTHVVVREDPYYSSGAPLAMGMLAGAATGAALGSLMWSPCWF", "length": 224 }, "evidence": [ { "id": "A0ABZ3NNR8", "url": "https://omabrowser.org/oma/group/A0ABZ3NNR8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9QYE9-1", "protein_name": "Pleckstrin homology domain-containing family B member 1", "gene_name": "Plekhb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPATPVPPDSILESPFEEMALVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVVIHFNVRDIKVGQECQDVQPPEGRSRDGLLTVNLREGSRLHLCAETRDDAIAWKTALMEANSTPAPAGATVPPRSRRVCPKVRCTTLSWNPCKVERRIWVRVYSPYQDYYEVVPPNAHEATYVRSYYGPPYAGPGVTHVIVREDPCYSSGAPLAMGMLAGAATGAALGSLMWSPCWF", "length": 243 }, "evidence": [ { "id": "A0ABZ3NNR8", "url": "https://omabrowser.org/oma/group/A0ABZ3NNR8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UF11-1", "protein_name": "Pleckstrin homology domain-containing family B member 1", "gene_name": "PLEKHB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSPAAPVPPDSALESPFEEMALVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVLIHFNVRDIKIGPECHDVQPPEGRSRDGLLTVNLREGGRLHLCAETKDDALAWKTALLEANSTPAPAGATVPPRSRRVCSKVRCVTRSWSPCKVERRIWVRVYSPYQDYYEVVPPNAHEATYVRSYYGPPYAGPGVTHVIVREDPCYSAGAPLAMGMLAGAATGAALGSLMWSPCWF", "length": 243 }, "evidence": [ { "id": "A0ABZ3NNR8", "url": "https://omabrowser.org/oma/group/A0ABZ3NNR8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WU68-1", "protein_name": "Pleckstrin homology domain-containing family B member 1", "gene_name": "Plekhb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVVIHFNVRDIKVGQECQDVQPPEGRSRDGLLTVNLREGSRLHLCAETRDDAIAWKTALMEANSTPAPAGATVPPRSRRVCPKVRCTSLSWKPCKVERRIWVRVYSPYQDYYEVVPPNAHEATYVRSYYGPPYGPGVTHVIVREDPCYSSGAPLAMGMLAGAATGAALGSLMWSPCWF", "length": 223 }, "evidence": [ { "id": "A0ABZ3NNR8", "url": "https://omabrowser.org/oma/group/A0ABZ3NNR8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNR8", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNR8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of cell differentiation", "id": "GO:0045595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045595", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNR8", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNR8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABZ3NNR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNR8" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 97, "end_pos": 204, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P672-1", "uniprot_ac": "A0ABI0P672", "uniprot_id": "A0ABI0P672_BOVIN", "mass": { "chemical_mass": 81844.0, "monoisotopic_mass": 81844.0 }, "refseq": { "ac": "XP_002689811", "name": "FHF complex subunit HOOK-interacting protein 2B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689811" }, "gene_names": [ { "name": "FHIP2B", "type": "recommended", "evidence": [ { "id": "A0ABI0P672", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P672" } ] }, { "name": "FHIP2B", "type": "synonym", "evidence": [ { "id": "XP_002689811", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689811" } ] } ], "protein_names": [ { "name": "FHF complex subunit HOOK interacting protein 2B", "type": "synonym", "evidence": [ { "id": "A0ABI0P672", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P672/entry#names_and_taxonomy" } ] }, { "name": "FHF complex subunit HOOK-interacting protein 2B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002689811", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689811" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P672", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P672" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FHIP2B", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P672", "locus": { "chromosome": "8", "start_pos": 69418370, "end_pos": 69401459, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014361", "url": "https://www.ensembl.org/id/ENSBTAG00000014361" } ] } } ], "crossref": [ { "id": "ENSBTAG00000014361", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014361", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "507256", "url": "https://www.ncbi.nlm.nih.gov/gene/507256", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507256", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507256", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1MDX7", "url": "https://www.orthodb.org/?gene=F1MDX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21705:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21705:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10257", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10257", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19311", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19311", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19314", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19314", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002689811", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689811", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M388", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M388", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M388-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M388-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P672", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P672", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P672-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P672-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MDX7", "url": "https://www.uniprot.org/uniprotkb/F1MDX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MDX7-1", "url": "https://www.uniprot.org/uniprotkb/F1MDX7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSRLGALLQEAVGAREPSIDLLEAFVEHWKGITNYYIESTDENTPAKKTDIPWRLKQMLDILVYEEKQQAAAGETGPCLEYLLQHKILETLCTLGKAEYPPGMRQQVLQFFSKVLAQVQHPLLHYLNVHRPVQKLLRLGGTVPGSLTEKEEVQFTTVLCSKIQQDPALLTYILEGKKTIGRKASREATAPLREAASVRDKDRPHIKAPDNGTCGAWASSAQLPAETEEPDGAIGESSLITTLIGLCKSKKGRVALKARENLLLLVSVASQAAATYLVQSSPCCPAIIEYLCQLYQSLPSSLDPADIAALEGISWRLPSAPSDEASFPGKEALAAFLGWFDYCDHLITEAHTVVSDALAKAVAEKLFVEILQPQLLHVSEQSVLMSTALLTVMLRQLRSPALLQEAVAFLLGMDQQPAAPEDSPRTLCTHLIRHCDHLSDEISIATLRLFEELLQKPHEHIVRSLILCHLEGRSYVARGSPEPESYEDTLDLEEDPYFTDSFLDSGFQPSVKPPPAPATNPDGKTAVTEIVNSFLCLVPEEAKTSAFLEETGYDTYVHDAYGLFQECSSRVTPWGWPLAPPPLDPHEPERPFFEGPFLQMLFDRMSRILEQPYSLNLQVTSVLSRLALFPHPLIHEYLLDPYTNLAPGCRSLFSVLVRVIGDLMQRIQRVPQFPGKLLLVRRQLMGQVPGEQLDHQTFLQGVVVLEEFCKELAAIAFVKFPPHGPRLHPSKPPEGHV", "length": 737, "header": "tr|A0ABI0P672-1|A0ABI0P672_BOVIN Isoform 1 of FHF complex subunit HOOK interacting protein 2B OS=Bos taurus OX=9913 GN=FHIP2B PE=3 SV=1 CANONICAL=A0ABI0P672-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M388-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P672/entry#A0A3Q1M388-1", "sequence": { "sequence": "MLSRLGALLQEAVGAREPSIDLLEAFVEHWKGITNYYIESTDENTPAKKTDIPWRLKQMLDILVYEEKQQAAAGETGPCLEYLLQHKILETLCTLGKAEYPPGMRQQVLQFFSKVLAQVQHPLLHYLNVHRPVQKLLRLGGTVPGSLTEKEEVQFTTVLCSKIQQDPALLTYILEGKKTIGRKASREATAPLREAASVRDKDRPHIKAPDNGTCGAWASSAQLPAETEEPDGAIGESSLITTLIGLCKSKKGRVALKARENLLLLVSVASQAAATYLVQSSPCCPAIIEYLCQLYQSLPSSLDPADIAALEGISWRLPSAPSDEASFPGKEALAAFLGWFDYCDHLITEAHTVVSDALAKAVAEKLFVEILQPQLLHVSEQSVLMSTALLTVMLRQLRSPALLQEAVAFLLGMDQQPAAPEDSPRTLCTHLIRHCDHLSDEISIATLRLFEELLQKPHEHIVRSLILCHLEGRSYVARGSPEPESYEDTLDLEEDPYFTDSFLDSGFQPSVKPPPAPATNPDGKTAVTEIVNSFLCLVPEEAKTSAFLEETGYDTYVHDAYGLFQECSSRVTPWGWPLAPPPLDPHEPERPFFEGPFLQMLFDRMSRILEQVIGDLMQRIQRVPQFPGKLLLVRRQLMGQVPGEQLDHQTFLQGVVVLEEFCKELAAIAFVKFPPHGPRLHPSKPPEGHV", "length": 690, "header": "tr|A0A3Q1M388-1|A0ABI0P672_BOVIN Computationally mapped isoform of FHF complex subunit HOOK interacting protein 2B OS=Bos taurus OX=9913 GN=FHIP2B PE=3 SV=2 CANONICAL=A0ABI0P672-1" }, "locus": { "chromosome": "8", "start_pos": 69417366, "end_pos": 69401582, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079616.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079616.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062613.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062613.2" } ] } }, { "isoform_ac": "A0ABI0P672-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P672/entry#A0ABI0P672-1", "sequence": { "sequence": "MLSRLGALLQEAVGAREPSIDLLEAFVEHWKGITNYYIESTDENTPAKKTDIPWRLKQMLDILVYEEKQQAAAGETGPCLEYLLQHKILETLCTLGKAEYPPGMRQQVLQFFSKVLAQVQHPLLHYLNVHRPVQKLLRLGGTVPGSLTEKEEVQFTTVLCSKIQQDPALLTYILEGKKTIGRKASREATAPLREAASVRDKDRPHIKAPDNGTCGAWASSAQLPAETEEPDGAIGESSLITTLIGLCKSKKGRVALKARENLLLLVSVASQAAATYLVQSSPCCPAIIEYLCQLYQSLPSSLDPADIAALEGISWRLPSAPSDEASFPGKEALAAFLGWFDYCDHLITEAHTVVSDALAKAVAEKLFVEILQPQLLHVSEQSVLMSTALLTVMLRQLRSPALLQEAVAFLLGMDQQPAAPEDSPRTLCTHLIRHCDHLSDEISIATLRLFEELLQKPHEHIVRSLILCHLEGRSYVARGSPEPESYEDTLDLEEDPYFTDSFLDSGFQPSVKPPPAPATNPDGKTAVTEIVNSFLCLVPEEAKTSAFLEETGYDTYVHDAYGLFQECSSRVTPWGWPLAPPPLDPHEPERPFFEGPFLQMLFDRMSRILEQPYSLNLQVTSVLSRLALFPHPLIHEYLLDPYTNLAPGCRSLFSVLVRVIGDLMQRIQRVPQFPGKLLLVRRQLMGQVPGEQLDHQTFLQGVVVLEEFCKELAAIAFVKFPPHGPRLHPSKPPEGHV", "length": 737, "header": "tr|A0ABI0P672-1|A0ABI0P672_BOVIN Isoform 1 of FHF complex subunit HOOK interacting protein 2B OS=Bos taurus OX=9913 GN=FHIP2B PE=3 SV=1 CANONICAL=A0ABI0P672-1" }, "locus": { "chromosome": "8", "start_pos": 69417366, "end_pos": 69401582, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149273.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149273.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106470.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106470.1" } ] } }, { "isoform_ac": "F1MDX7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P672/entry#F1MDX7-1", "sequence": { "sequence": "MLSRLGALLQEAVGAREPSIDLLEAFVEHWKGITNYYIESTDENTPAKKTDIPWRLKQMLDILVYEEKQQAAAGETGPCLEYLLQHKILETLCTLGKAEKLLRLGGTVPGSLTEKEEVQFTTVLCSKIQQDPALLTYILEGKKTIGRKASREATAPLREAASVRDKDRPHIKAPDNGTCGAWASSAQLPAETEEPDGAIGESSLITTLIGLCKSKKGRVALKARENLLLLVSVASQAAATYLVQSSPCCPAIIEYLCQLYQSLPSSLDPADIAALEGISWRLPSAPSDEASFPGKEALAAFLGWFDYCDHLITEAHTVVSDALAKAVAEKLFVEILQPQLLHVSEQSVLMSTALLTVMLRQLRSPALLQEAVAFLLGMDQQPAAPEDSPRTLCTHLIRHCDHLSDEISIATLRLFEELLQKPHEHIVRSLILCHLEGRSYVARGSPEPESYEDTLDLEEDPYFTDSFLDSGFQPSVKPPPAPATNPDGKTAVTEIVNSFLCLVPEEAKTSAFLEETGYDTYVHDAYGLFQECSSRVTPWGWPLAPPPLDPHEPERPFFEGPFLQMLFDRMSRILEQPYSLNLQVTSVLSRLALFPHPLIHEYLLDPYTNLAPGCRSLFSVLVRVIGDLMQRIQRVPQFPGKLLLVRRQLMGQVPGEQLDHQTFLQGVVVLEEFCKELAAIAFVKFPPHGPRLHPSKPPEGHV", "length": 702, "header": "tr|F1MDX7-1|A0ABI0P672_BOVIN Computationally mapped isoform of FHF complex subunit HOOK interacting protein 2B OS=Bos taurus OX=9913 GN=FHIP2B PE=3 SV=4 CANONICAL=A0ABI0P672-1" }, "locus": { "chromosome": "8", "start_pos": 69417366, "end_pos": 69401582, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036592.7", "url": "https://www.ensembl.org/id/ENSBTAT00000036592.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036449.6", "url": "https://www.ensembl.org/id/ENSBTAP00000036449.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:507256", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507256", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P672", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P672" }, { "id": "PF19314", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19314" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FHF complex subunit HOOK-interacting protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 594, "end_pos": 686, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P6E9-1", "uniprot_ac": "A0ABI0P6E9", "uniprot_id": "A0ABI0P6E9_BOVIN", "mass": { "chemical_mass": 107002.0, "monoisotopic_mass": 107002.0 }, "refseq": {}, "gene_names": [ { "name": "ROBO4", "type": "recommended", "evidence": [ { "id": "A0ABI0P6E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E9" } ] } ], "protein_names": [ { "name": "Roundabout homolog 4", "type": "recommended", "evidence": [ { "id": "A0ABI0P6E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins. Involved in the maintenance of endothelial barrier organization and function.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P6E9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E9#function" }, { "database": "UniProtKB", "id": "ARBA00057910", "url": "https://www.uniprot.org/uniprotkb/ARBA00057910#function" }, { "database": "UniProtKB", "id": "F1MSU7", "url": "https://www.uniprot.org/uniprotkb/F1MSU7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P6E9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ROBO4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E9", "locus": { "chromosome": "29", "start_pos": 28351069, "end_pos": 28365789, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004356", "url": "https://www.ensembl.org/id/ENSBTAG00000004356" } ] } } ], "crossref": [ { "id": "ENSBTAG00000004356", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004356", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MSU7", "url": "https://www.orthodb.org/?gene=F1MSU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0P6E9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6E9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MSU7", "url": "https://www.uniprot.org/uniprotkb/F1MSU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MSU7-1", "url": "https://www.uniprot.org/uniprotkb/F1MSU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAGGARLLGVHWALPLLLLTGSMAQDFPPQILVHPEDQLFQGPDPAKMSCRASGQPPPTIRWLLDGHPLSMVPPDVHHLLPDGTLLLLRPPPRGRAHDDHTRSTDLGVYTCEASNRLGTAVSRGARLSMAVLQEDFQVQPRDTVAAVGEQVLLQCEPPWGHPEPTVSWWKDEKPLALQSGRHSVSQGSLLMARAEKSDAGTYMCMATNSAGQRKSRVARVSIQEPRDYKEPLELLAVHIQLENVTLLNPDPKKGTKPGPAGWLSWKVSGPAAPAQSYTALFRTQAAPGGQGAPWAEVLLAGWQSAELGGLHWGQDYEFKVRPSSGRAQGPDSNVLLLRLPEQVPSAPPQEVTLKPGNGTILVSWIPPPAENHNGIIRGYQVWSLGNTSLPPANWTVVGEQTQLEIATRMSGSYCIQVAAVTGAGAGQPSSPVCLLLEQAMERAAQQPSAHSPWTLEQLWAALKRPEVIASGGVVLWLLLLGIAVCIHRRRRAGVRLGPGLYRYTSEDAILKHRMDHSDSPWLADTWRSTSGSRDLSSSSSLSSRLGVDPRDPLDGRRSLISWDPRSPGVPLLPDTSTFYGSLIAEGPSSPPARPSPQAPAARRLTPQLAQLSSPWPSSDSLCGRRGLSSPRLSLAPAEAWKARKKQELHQANSSPLLRASHPAELWACELGNRGSKNFSQSPGAVPRALVAWRALGPQLLSSSSELMTRPLPPVPLAPRGPPTQSQQTQHSGEPPAPTSPPPPAAPVPALIPSGTLHVSSPQASSLSGPSPASSRLSSSSLSSLGEDQDSVLTPEEVALCLELSDGEETPRNSVSPMPRAPSPPITYGYISVPTASDLADMGRPGGGVGSEVRGLLCPPRPCLTPTPSEGSLANGWGSASEDNGPSARASLVSSSDGSFLADAHFARALAVAADSFGFGLEPREADCVFTDASSPPSPRDDLSLTSTLSLTPWEWRSDWLEDIEKNPTQWLGRGLPPWLPETRISSQKSQLSSPVPKAGASDSS", "length": 1005, "header": "tr|A0ABI0P6E9-1|A0ABI0P6E9_BOVIN Isoform 1 of Roundabout homolog 4 OS=Bos taurus OX=9913 GN=ROBO4 PE=3 SV=1 CANONICAL=A0ABI0P6E9-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P6E9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E9/entry#A0ABI0P6E9-1", "sequence": { "sequence": "MGAGGARLLGVHWALPLLLLTGSMAQDFPPQILVHPEDQLFQGPDPAKMSCRASGQPPPTIRWLLDGHPLSMVPPDVHHLLPDGTLLLLRPPPRGRAHDDHTRSTDLGVYTCEASNRLGTAVSRGARLSMAVLQEDFQVQPRDTVAAVGEQVLLQCEPPWGHPEPTVSWWKDEKPLALQSGRHSVSQGSLLMARAEKSDAGTYMCMATNSAGQRKSRVARVSIQEPRDYKEPLELLAVHIQLENVTLLNPDPKKGTKPGPAGWLSWKVSGPAAPAQSYTALFRTQAAPGGQGAPWAEVLLAGWQSAELGGLHWGQDYEFKVRPSSGRAQGPDSNVLLLRLPEQVPSAPPQEVTLKPGNGTILVSWIPPPAENHNGIIRGYQVWSLGNTSLPPANWTVVGEQTQLEIATRMSGSYCIQVAAVTGAGAGQPSSPVCLLLEQAMERAAQQPSAHSPWTLEQLWAALKRPEVIASGGVVLWLLLLGIAVCIHRRRRAGVRLGPGLYRYTSEDAILKHRMDHSDSPWLADTWRSTSGSRDLSSSSSLSSRLGVDPRDPLDGRRSLISWDPRSPGVPLLPDTSTFYGSLIAEGPSSPPARPSPQAPAARRLTPQLAQLSSPWPSSDSLCGRRGLSSPRLSLAPAEAWKARKKQELHQANSSPLLRASHPAELWACELGNRGSKNFSQSPGAVPRALVAWRALGPQLLSSSSELMTRPLPPVPLAPRGPPTQSQQTQHSGEPPAPTSPPPPAAPVPALIPSGTLHVSSPQASSLSGPSPASSRLSSSSLSSLGEDQDSVLTPEEVALCLELSDGEETPRNSVSPMPRAPSPPITYGYISVPTASDLADMGRPGGGVGSEVRGLLCPPRPCLTPTPSEGSLANGWGSASEDNGPSARASLVSSSDGSFLADAHFARALAVAADSFGFGLEPREADCVFTDASSPPSPRDDLSLTSTLSLTPWEWRSDWLEDIEKNPTQWLGRGLPPWLPETRISSQKSQLSSPVPKAGASDSS", "length": 1005, "header": "tr|A0ABI0P6E9-1|A0ABI0P6E9_BOVIN Isoform 1 of Roundabout homolog 4 OS=Bos taurus OX=9913 GN=ROBO4 PE=3 SV=1 CANONICAL=A0ABI0P6E9-1" }, "locus": { "chromosome": "29", "start_pos": 28365768, "end_pos": 28351733, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144608.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144608.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106920.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106920.1" } ] } }, { "isoform_ac": "F1MSU7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E9/entry#F1MSU7-1", "sequence": { "sequence": "MGAGGARLLGVHWALPLLLLTGSMAQDFPPQILVHPEDQLFQGPDPAKMSCRASGQPPPTIRWLLDGHPLSMVPPDVHHLLPDGTLLLLRPPPRGRAHDDHTRSTDLGVYTCEASNRLGTAVSRGARLSMAVLQEDFQVQPRDTVAAVGEQVLLQCEPPWGHPEPTVSWWKDEKPLALQSGRHSVSQGSLLMARAEKSDAGTYMCMATNSAGQRKSRVARVSIQEPRDYKEPLELLAVHIQLENVTLLNPDPKKGTKPGPAGWLSWKVSGPAAPAQSYTALFRTQAAPGGQGAPWAEVLLAGWQSAELGGLHWGQDYEFKVRPSSGRAQGPDSNVLLLRLPEQVPSAPPQEVTLKPGNGTILVSWIPPPAENHNGIIRGYQVWSLGNTSLPPANWTVVGEQTQLEIATRMSGSYCIQVAAVTGAGAGQPSSPVCLLLEQAMERAAQQPSAHSPWTLEQLWAALKRPEVIASGGVVLWLLLLGIAVCIHRRRRAGVRLGPGLYRYTSEDAILKHRMDHSDSPWLADTWRSTSGSRDLSSSSSLSSRLGVDPRDPLDGRRSLISWDPRSPGVPLLPDTSTFYGSLIAEGPSSPPARPSPQAPAARRLTPQLAQLSSPWPSSDSLCGRRGLSSPRLSLAPAEAWKARKKQELHQANSSPLLRASHPAELWACELGNRGSKNFSQSPGAVPRALVAWRALGPQLLSSSSELMTRPLPPVPLAPRGPPTQSQQTQHSGEPPAPTSPPPPAAPVPALIPSGTLHVSSPQASSLSGPSPASSRLSSSSLSSLGEDQDSVLTPEEVALCLELSDGEETPRNSVSPMPRAPSPPITYGYISVPTASDLADMGRPGGGVGSEVRGLLCPPRPCLTPTPSEGSLANGWGSASEDNGPSARASLVSSSDGSFLADAHFARALAVAADSFGFGLEPREADCVFTDASSPPSPRDDLSLTSTLSLTPWEWRSDWLEDIEKNPTQWLGRGLPPWLPETRISSQKSQLSSPVPKAGDSS", "length": 1003, "header": "tr|F1MSU7-1|A0ABI0P6E9_BOVIN Computationally mapped isoform of Roundabout homolog 4 OS=Bos taurus OX=9913 GN=ROBO4 PE=3 SV=5 CANONICAL=A0ABI0P6E9-1" }, "locus": { "chromosome": "29", "start_pos": 28365768, "end_pos": 28351733, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005698.8", "url": "https://www.ensembl.org/id/ENSBTAT00000005698.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005698.8", "url": "https://www.ensembl.org/id/ENSBTAP00000005698.8" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 166, "start_aa": "Thr", "end_pos": 166, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr166", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 739, "start_aa": "Thr", "end_pos": 739, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr739", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 867, "start_aa": "Thr", "end_pos": 867, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr867", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P6E9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 653, "end_pos": 655, "annotation": "n_glycosylation_sequon" }, { "start_pos": 678, "end_pos": 680, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P6E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E9" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 345, "end_pos": 440, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ABI0P6E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6E9" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 129, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 166, 739, 867 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 244, "end_pos": 246 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 653, "end_pos": 655 }, { "start_pos": 678, "end_pos": 680 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 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"MAWALKLPLADEVIESGLVQDFDASLSGIGQELGAGAYSMSDVLALPIFKQEESSLPPDNENKILPFQYVLCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKLGELPEINGKLVKSIFRVVFHDRRLQYTEHQQLEGWRWNRPGDRILDIDIPMSVGIIDPRANPNQLNTVEFLWDPAKRTSVFIQVHCISTEFTMRKHGGEKGVPFRVQIDTFKENENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTPHEKEKYQPSYETTILTECSPWPEITYVNNSPSPGFNSSHSSFSLGEGNGSPNHQPEPPPPVTDNLLPTTTPQEAQQWLHRNRFSTFTRLFTNFSGADLLKLTRDDVIQICGPADGIRLFNALKGRMVRPRLTIYVCQESLQLREQQQQQQNQQKHEDGDSNGTFFVYHAIYLEELTAVELTEKIAQLFSISPCQISQIYKQGPTGIHVLISDEMIQNFQEEACFILDTMKAETNDSYHIILK", "length": 501, "header": "tr|A0ABZ3NNI1-1|A0ABZ3NNI1_BOVIN Isoform 1 of Transcription factor CP2 OS=Bos taurus OX=9913 GN=TFCP2 PE=3 SV=1 CANONICAL=A0ABZ3NNI1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M0I7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNI1/entry#A0A3Q1M0I7-1", "sequence": { "sequence": 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"Ensembl Peptide", "id": "ENSBTAP00000068660.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068660.2" } ] } }, { "isoform_ac": "A0ABI0P4G9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNI1/entry#A0ABI0P4G9-1", "sequence": { "sequence": "MAWALKLPLADEVIESGLVQDFDASLSGIGQELGAGAYSMSDVLALPIFKQEESSLPPDNENKILPFQYVLCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKLGELPEINGKLVKSIFRVVFHDRRLQYTEHQQLEGWRWNRPGDRILDIDIPMSVGIIDPRANPNQLNTVEFLWDPAKRTSVFIQVHCISTEFTMRKHGGEKGVPFRVQIDTFKENENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTPHEKEKYQPSYETTILTECSPWPEITYVNNSPSPGFNSSHSSFSLGEGNGSPNHQPEPPPPVTDNLLPTTTPQEAQQWLHRNRFSTFTRLFTNFSGADLLKLTRDDVIQICGPADGIRLFNALKGRMVRPRLTIYVCQESLQLREQQQQQQNQQKHEDGDSNVYHAIYLEELTAVELTEKIAQLFSISPCQISQIYKQGPTGIHVLISDEMIQNFQEEACFILDTMKAETNDSYHIILK", "length": 497, "header": "tr|A0ABI0P4G9-1|A0ABZ3NNI1_BOVIN Computationally mapped isoform of Transcription factor CP2 OS=Bos taurus OX=9913 GN=TFCP2 PE=3 SV=1 CANONICAL=A0ABZ3NNI1-1" }, "locus": { "chromosome": "5", "start_pos": 28662463, "end_pos": 28611435, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141402.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141402.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106624.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106624.1" } ] } }, { "isoform_ac": "A0ABZ3NNI1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNI1/entry#A0ABZ3NNI1-1", "sequence": { "sequence": "MAWALKLPLADEVIESGLVQDFDASLSGIGQELGAGAYSMSDVLALPIFKQEESSLPPDNENKILPFQYVLCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKLGELPEINGKLVKSIFRVVFHDRRLQYTEHQQLEGWRWNRPGDRILDIDIPMSVGIIDPRANPNQLNTVEFLWDPAKRTSVFIQVHCISTEFTMRKHGGEKGVPFRVQIDTFKENENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTPHEKEKYQPSYETTILTECSPWPEITYVNNSPSPGFNSSHSSFSLGEGNGSPNHQPEPPPPVTDNLLPTTTPQEAQQWLHRNRFSTFTRLFTNFSGADLLKLTRDDVIQICGPADGIRLFNALKGRMVRPRLTIYVCQESLQLREQQQQQQNQQKHEDGDSNGTFFVYHAIYLEELTAVELTEKIAQLFSISPCQISQIYKQGPTGIHVLISDEMIQNFQEEACFILDTMKAETNDSYHIILK", "length": 501, "header": "tr|A0ABZ3NNI1-1|A0ABZ3NNI1_BOVIN Isoform 1 of Transcription factor CP2 OS=Bos taurus OX=9913 GN=TFCP2 PE=3 SV=1 CANONICAL=A0ABZ3NNI1-1" }, "locus": { "chromosome": "5", "start_pos": 28662463, "end_pos": 28611435, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025713.7", "url": "https://www.ensembl.org/id/ENSBTAT00000025713.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025713.7", "url": "https://www.ensembl.org/id/ENSBTAP00000025713.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:509448", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509448", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNI1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNI1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNI1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNI1" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNI1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNI1" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNI1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNI1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNI1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNI1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNI1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNI1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNI1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABZ3NNI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNI1" }, { "id": "PS51968", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51968" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Grh/CP2 DB", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 300, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 287, "end_pos": 289 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 351, "end_pos": 353 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 493, "end_pos": 495 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P5B6-1", "uniprot_ac": "A0ABI0P5B6", "uniprot_id": "A0ABI0P5B6_BOVIN", "mass": { "chemical_mass": 97806.0, "monoisotopic_mass": 97806.0 }, "refseq": { "ac": "NP_001192640", "name": "scm-like with four MBT domains protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192640" }, "gene_names": [ { "name": "SFMBT1", "type": "recommended", "evidence": [ { "id": "A0ABI0P5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6" } ] }, { "name": "SFMBT1", "type": "synonym", "evidence": [ { "id": "NP_001192640", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192640" } ] } ], "protein_names": [ { "name": "Scm like with four mbt domains 1", "type": "synonym", "evidence": [ { "id": "A0ABI0P5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6/entry#names_and_taxonomy" } ] }, { "name": "scm-like with four MBT domains protein 1", "type": "synonym", "evidence": [ { "id": "NP_001192640", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192640" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5B6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SFMBT1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6", "locus": { "chromosome": "22", "start_pos": 47996531, "end_pos": 47888282, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011345", "url": "https://www.ensembl.org/id/ENSBTAG00000011345" } ] } } ], "crossref": [ { "id": "ENSBTAG00000011345", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011345", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09581", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09581", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20111", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20111", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20113", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20113", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20115", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20115", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20117", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20117", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "511984", "url": "https://www.ncbi.nlm.nih.gov/gene/511984", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047351", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047351", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511984", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511984", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HWSLKNG", "url": "https://omabrowser.org/oma/group/HWSLKNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MMQ1", "url": "https://www.orthodb.org/?gene=F1MMQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247:SF77", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247:SF77", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192640", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192640", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LT91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LT91-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBQ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5B6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5B6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MMQ1", "url": "https://www.uniprot.org/uniprotkb/F1MMQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MMQ1-1", "url": "https://www.uniprot.org/uniprotkb/F1MMQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGEQQTDADAGSGVEEVELSWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVKTDPETYWVATIITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLTGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVDNIGGRLKLRYEGLEGSDNVEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVKEEEEPLPSYLFKDKRVIGTHSFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRLENRGQRSFVCHTDSPGIFPVQWSLKNGLHISPPPGYQGQDFDWADYLKQCGAEAAPQRCFPPSISEHEFKENMKLEAVNPLLPEEVCVATITAVRGSYLWLQLEGSKKPIPEFIVNVESMDIFPLGWCETNGHPLSTPRRARVHKQRKIAVVQPEKQIPSSRTVHEGLKNQELSSTDSVVINGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVKTADRVTEFCRQTCIKLECCPNLFGPRMVLDKCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLACALKKASKRRKRRKNVFVHKKKRSSASVDNTPAGSPQGSGGEDEEDPDEGDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRIEVAERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN", "length": 865, "header": "tr|A0ABI0P5B6-1|A0ABI0P5B6_BOVIN Isoform 1 of Scm like with four mbt domains 1 OS=Bos taurus OX=9913 GN=SFMBT1 PE=4 SV=1 CANONICAL=A0ABI0P5B6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LT91-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6/entry#A0A3Q1LT91-1", "sequence": { "sequence": "MKLEVAVKTDPETYWVATIITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLTGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVDNIGGRLKLRYEGLEGSDNVEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVKEEEEPLPSYLFKDKRVIGTHSFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRLENRGQRSFVCHTDSPGIFPVQWSLKNGLHISPPPGYQGQDFDWADYLKQCGAEAAPQRCFPPSISEHEFKENMKLEAVNPLLPEEVCVATITAVRGSYLWLQLEGSKKPIPEFIVNVESMDIFPLGWCETNGHPLSTPRRARVHKQRKIAVVQPEKQIPSSRTVHEGLKNQELSSTDSVVINGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVKTADRVTEFCRQTCIKLECCPNLFGPRMVLDKCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLACALKKASKRRKRRKNVFVHKKKRSSASVDNTPAGSPQGSGGEDEEDPDEGDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRIEVAERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN", "length": 812, "header": "tr|A0A3Q1LT91-1|A0ABI0P5B6_BOVIN Computationally mapped isoform of Scm like with four mbt domains 1 OS=Bos taurus OX=9913 GN=SFMBT1 PE=4 SV=2 CANONICAL=A0ABI0P5B6-1" }, "locus": { "chromosome": "22", "start_pos": 47992071, "end_pos": 47958427, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079599.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079599.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060273.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060273.2" } ] } }, { "isoform_ac": "A0AAA9TBQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6/entry#A0AAA9TBQ2-1", "sequence": { "sequence": "MQVDTRLQNGFAPGMKLEVAVKTDPETYWVATIITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLTGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVDNIGGRLKLRYEGLEGSDNVEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVKEEEEPLPSYLFKDKRVIGTHSFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRLENRGQRSFVCHTDSPGIFPVQWSLKNGLHISPPPGYQGQDFDWADYLKQCGAEAAPQRCFPPSISEHEFKENMKLEAVNPLLPEEVCVATITAVRGSYLWLQLEGSKKPIPEFIVNVESMDIFPLGWCETNGHPLSTPRRARVHKQRKIAVVQPEKQIPSSRTVHEGLKNQELSSTDSVVINGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVKTADRVTEFCRQTCIKLECCPNLFGPRMVLDKCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLACALKKASKRRKRRKNVFVHKKKRSSASVDNTPAGSPQGSGGEDEEDPDEGDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRIEVAERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN", "length": 826, "header": "tr|A0AAA9TBQ2-1|A0ABI0P5B6_BOVIN Computationally mapped isoform of Scm like with four mbt domains 1 OS=Bos taurus OX=9913 GN=SFMBT1 PE=4 SV=1 CANONICAL=A0ABI0P5B6-1" }, "locus": { "chromosome": "22", "start_pos": 47992071, "end_pos": 47943536, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125241.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125241.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093515.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093515.1" } ] } }, { "isoform_ac": "A0ABI0P5B6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6/entry#A0ABI0P5B6-1", "sequence": { "sequence": "MNGEQQTDADAGSGVEEVELSWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVKTDPETYWVATIITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLTGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVDNIGGRLKLRYEGLEGSDNVEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVKEEEEPLPSYLFKDKRVIGTHSFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRLENRGQRSFVCHTDSPGIFPVQWSLKNGLHISPPPGYQGQDFDWADYLKQCGAEAAPQRCFPPSISEHEFKENMKLEAVNPLLPEEVCVATITAVRGSYLWLQLEGSKKPIPEFIVNVESMDIFPLGWCETNGHPLSTPRRARVHKQRKIAVVQPEKQIPSSRTVHEGLKNQELSSTDSVVINGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVKTADRVTEFCRQTCIKLECCPNLFGPRMVLDKCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLACALKKASKRRKRRKNVFVHKKKRSSASVDNTPAGSPQGSGGEDEEDPDEGDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRIEVAERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN", "length": 865, "header": "tr|A0ABI0P5B6-1|A0ABI0P5B6_BOVIN Isoform 1 of Scm like with four mbt domains 1 OS=Bos taurus OX=9913 GN=SFMBT1 PE=4 SV=1 CANONICAL=A0ABI0P5B6-1" }, "locus": { "chromosome": "22", "start_pos": 47992071, "end_pos": 47943514, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143394.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143394.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106567.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106567.1" } ] } }, { "isoform_ac": "F1MMQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6/entry#F1MMQ1-1", "sequence": { "sequence": "MNGEQQTDADAGSGVEEVELSWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVKTDPETYWVATIITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLTGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVDNIGGRLKLRYEGLEGSDNVEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVKEEEEPLPSYLFKDKRVIGTHSFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRLENRGQRSFVCHTDSPGIFPVQWSLKNGLHISPPPGYQGQDFDWADYLKQCGAEAAPQRCFPPSISEHEFKENMKLEAVNPLLPEEVCVATITAVRGSYLWLQLEGSKKPIPEFIVNVESMDIFPLGWCETNGHPLSTPRRARVHKQRKIAVVQPEKQIPSSRTVHEGLKNQELSSTDSVVINGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVKTADRVTEFCRQTCIKLECCPNLFGPRMVLDKCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLACALKKASKRRKRRKNVFVHKKKRSSASVDNTPAGSPQGSGGEDEEDPDEGDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRIEVAERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQCFASEFL", "length": 826, "header": "tr|F1MMQ1-1|A0ABI0P5B6_BOVIN Computationally mapped isoform of Scm like with four mbt domains 1 OS=Bos taurus OX=9913 GN=SFMBT1 PE=4 SV=4 CANONICAL=A0ABI0P5B6-1" }, "locus": { "chromosome": "22", "start_pos": 47996353, "end_pos": 47943514, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061279.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061279.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053475.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053475.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:511984", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511984", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VLZ5-1", "protein_name": "Scm like with four mbt domains 1", "gene_name": "SFMBT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNGEQQIDADAGSSVEEVELSWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVVVKTNPEAYWVATIITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWNEFLRQTLMGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVDNIGGRLKLRYEGLESSDNFELWLYYLDPFLHHVGWAAQQGYELQPPLAIKHLKNEDEWQEILTKVKEEEEEPLPSYLFKDKPVIGMHSFSVNMKLEAVDPWSPFGICPATVVKVFDEKYFLVEMDDLRPENHAQRSFVCHANSPGIFPVQWSLKNGLHISPPPGYPGQDFDWADYLKQCGAEAAPQRCFPPSISEHEFKENMKLEAVNPLLPEEVCVATITAVRGSYLWLQLEGSKKPIPEFIVNVESMDIFPLGWCETNGHPLSAPRRARVHKQRKIAVVQPEKQIPSSRAVHEGLKNQELNSTDSVMVNGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVKTADRVTEFCRQTCIKLECCPNLFGPRMVLDKCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLACALKKASKRRKRRKNVFVHKKKRSSTSVDNTPAGSPQGSGGEDEDDPDEGDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTSIPPDRQRRKRELRTFSFSDDENKPPSPKEIRIEVAERLHLDTNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN", "length": 866 }, "evidence": [ { "id": "A0ABI0P5B6", "url": "https://omabrowser.org/oma/group/A0ABI0P5B6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9JMD1-1", "protein_name": "Scm-like with four MBT domains protein 1", "gene_name": "Sfmbt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGEQQLDADLGSGVEVEEFSWEDYLEETGSTTVPYASFKHVDIRLQNGFAPGMKLEVALKNDPETYWVATIITACEQLLLLRYEGYGEDRKADFWCDIRKAGLYPIGWCQQNKKTLEAPEGIRDKVSDWNAFLQQTLIGACGPPVSLLEGLRNGRNPLDLIAPGSKLECQDFRDSLSTWLVTVVENIGGRLKLRYEGLESRDGFEHWLYYLDPFLHHIGWAAQQGCDLQPPLAIKHLKSEADWQEILAKVKEEEPLPSYLFKDKQVIGTHEFSINMKLEAVDPWSPFGISPATIAKVFDDKYFLVEMDDLRPEDHTRRSFVCHANSPGIFPVQWSLKNGLHINPPPGFRSQDFDWADYLKQCGAEAAPQKCFPQSISEHQFKENMKLEAVNPLFPEEVCIATVTAVRGSYLWLQLEGSKKPVPEFIVSAESMNIFPLGWCETNGHPLSTPRRARGHKLRKIAVVQPEKQILSSRTVHEGLKNQLNSTHSVMINGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVRTADRVTEFCRQTCIKLECCPNLFGPRMVLDTCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLSCALKKSSKRRKRRKNIFVHKKKRSSASVDNTPVGSPQGSGGEDEEDADDGDEDSLTEGSTSEQQEELQEESEVSEKKSSSSSPTQSETPTPLPPDTQTNKRDAQTSSVSDDENKPPSPKEIRIEVDERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN", "length": 863 }, "evidence": [ { "id": "A0ABI0P5B6", "url": "https://omabrowser.org/oma/group/A0ABI0P5B6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JMD2-1", "protein_name": "Scm-like with four MBT domains protein 1", "gene_name": "Sfmbt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGEQQLDADLGSGVEVEEFSWEDYLEETGATTAPYASFKHVDICLQSGFAPGMKLEVALRKDPETYWVATVITACEQLLLLRYEGYGEDRKADFWCDIRRAGLYPIGWCQQNKKTLEAPEGIRDKVSDWSAFLQRTLTGACGPPVALLEGLRNGRNPLDLIAPGSRLECQDFRDSVSTWIVTVVENIGGRLKLQYEGLERHDGFEHWLYYLDPFLHHIGWAAQQGYELQPPLAIRHLKNEADWQEILARVKEEEPLPSYLFKDKQVIRTHEFSINMKLEAVDPWSPFGISPATIAKVFDDKYFLVEIDDLRPEDHARRSFVCHANSPGIFPVQWSLKNGLHINPPPGFRSQDFDWADYLKQCGAEAAPQKCFPQSVSEHQFKENMKLEAVNPLFPEEVSIATVTAVRGSYLWLQLEGSKKPVPEFIVSVESMNIFPLGWCETNGHPLSTPRRARGHKLRKIAVVQPEKQILSSRTVHEGLKNQLNSPHSVMINGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVRTADRVTEFCRQTCIKLECCPNLFGPRMVLDTCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLSCALKKTSKRRKRRKNIFVHKKKRSSASVDNTPVGSPQGSGGEDEDDADDGDDDSLTEGSTSEQQDELHEESEVSEKKSCSPSPTQSEMSTPLPPDTQTDKREAQTSSLSDGENKPPSPKEIRIEVDERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN", "length": 863 }, "evidence": [ { "id": "A0ABI0P5B6", "url": "https://omabrowser.org/oma/group/A0ABI0P5B6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UHJ3-1", "protein_name": "Scm-like with four MBT domains protein 1", "gene_name": "SFMBT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGEQQLDADAGSGMEEVELSWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVRTDPETYWVATVITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDWDEFLRQTLIGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVENIGGRLKLRYEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVKEEEEEPLPSYLFKDKQVIGIHTFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRPENHARRSFVCHADSPGIFPVQWSLKNGLHISPPPGYPSQDFDWADYLKQCGAEAAPQRCFPPLISEHEFKENMKLEAVNPILPEEVCVATITAVRGSYLWLQLEGSKKPIPECIVSVESMDIFPLGWCETNGHPLSTPRRARVYKQRKIAVVQPEKQVPSSRTVHEGLRNQELNSTESVMINGKYCCPKIYFNHRCFSGPYLNKGRIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRATVEIVKTADRVTEFCRQTCIKLECCPNLFGPRMVLDKCSENCSVLTKTKYTHYYGKKKNKRIGRPPGGHSNLACALKKASKRRKRRKNVFVHKKKRSSASVDNTPAGSPQGSGGEDEDDPDEGDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIRIEVAERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGPAIKLCHHIERIKFAFYEQFAN", "length": 866 }, "evidence": [ { "id": "A0ABI0P5B6", "url": "https://omabrowser.org/oma/group/A0ABI0P5B6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5B6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5B6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5B6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5B6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5B6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5B6" }, { "id": "PS51079", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51079" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MBT", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 120, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 625, "end_pos": 627 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P626-1", "uniprot_ac": "A0ABI0P626", "uniprot_id": "A0ABI0P626_BOVIN", "mass": { "chemical_mass": 25787.0, "monoisotopic_mass": 25787.0 }, "refseq": { "ac": "NP_001193072", "name": "DNA-directed RNA polymerase III subunit RPC7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193072" }, "gene_names": [ { "name": "POLR3G", "type": "recommended", "evidence": [ { "id": "A0ABI0P626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P626" } ] }, { "name": "POLR3G", "type": "synonym", "evidence": [ { "id": "NP_001193072", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193072" } ] } ], "protein_names": [ { "name": "DNA-directed RNA polymerase III subunit RPC7", "type": "synonym", "evidence": [ { "id": "NP_001193072", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193072" } ] }, { "name": "RNA polymerase III subunit G", "type": "synonym", "evidence": [ { "id": "A0ABI0P626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P626/entry#names_and_taxonomy" } ] }, { "name": "polymerase (RNA) III (DNA directed) polypeptide G (32kD) like", "type": "synonym", "evidence": [ { "id": "NP_001193072", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193072" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P626", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P626" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "POLR3G", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P626", "locus": { "chromosome": "7", "start_pos": 90081729, "end_pos": 90036150, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000044077", "url": "https://www.ensembl.org/id/ENSBTAG00000044077" } ] } } ], "crossref": [ { "id": "ENSBTAG00000044077", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000044077", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613778", "url": "https://www.ncbi.nlm.nih.gov/gene/613778", 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CANONICAL=A0ABI0P626-1" }, "locus": { "chromosome": "7", "start_pos": 90080725, "end_pos": 90036275, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095590.2", "url": "https://www.ensembl.org/id/ENSBTAT00000095590.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092849.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092849.1" } ] } }, { "isoform_ac": "A0ABI0P626-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P626/entry#A0ABI0P626-1", "sequence": { "sequence": "MAGNKGRGRAAYTFNIEAVGFSRGEKLPDVVLKPPPLFPDTDYKPVPLKTGESEDYVLALKQELRETVKRMPYFVETPEEKQDIERYSKRYMKVYKEEWIPDWRRLPRELMPRKKCIKAGPKSKKAKDTGKGPSLTNPADVLKKIEELEKKGDGEKSDEENEEKEGSKEKSKEGDDDEEDDAAEQEEYDEEEQEEENDYINSYFEDGDDFGVDSDDNMDEATY", "length": 223, "header": "tr|A0ABI0P626-1|A0ABI0P626_BOVIN Isoform 1 of RNA polymerase III subunit G OS=Bos taurus OX=9913 GN=POLR3G PE=3 SV=1 CANONICAL=A0ABI0P626-1" }, "locus": { "chromosome": "7", "start_pos": 90080725, "end_pos": 90050518, "strand": 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"crossref": [ { "id": "ENSBTAG00000050377", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000050377", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00070", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00070", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "787811", "url": "https://www.ncbi.nlm.nih.gov/gene/787811", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:787811", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787811", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GWESEDR", "url": "https://omabrowser.org/oma/group/GWESEDR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11346:SF107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11346:SF107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00337", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00337", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002695021", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002695021", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MTP5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MTP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT80", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT80-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1N0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1N0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1N0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P701", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P701", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P701-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P701-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGSFNVPHKTSLPEGIRVGTVLRIRGLVPDKAGRFYVNLLCGEEPGSDAALHFNPRLDESTVVFNTLERGTWGAEERGSGIPFQRGQPFDVLLIATEEGFKAVIADSEYHHFRYRIPPGRVRALEVGGDLQLELVKIF", "length": 139, "header": "tr|A0ABI0P701-1|A0ABI0P701_BOVIN Isoform 1 of Galectin OS=Bos taurus OX=9913 GN=LGALS7 PE=1 SV=1 CANONICAL=A0ABI0P701-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MTP5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P701/entry#A0A3Q1MTP5-1", "sequence": { "sequence": "MAGASEALERGCWASMAPGSVPGVGGGCGKAESPGPGTPCFDLRSQQPRPHCHCRPAVPAMAGSFNVPHKTSLPEGIRVGTVLRIRGLVPDKAGRFYVNLLCGEEPGSDAALHFNPRLDESTVVFNTLERGTWGAEERGSGIPFQRGQPFDVLLIATEEGFKAVIADSEYHHFRYRIPPGRVRALEVGGDLQLELVKIF", "length": 199, "header": "tr|A0A3Q1MTP5-1|A0ABI0P701_BOVIN Computationally mapped isoform of Galectin OS=Bos taurus OX=9913 GN=LGALS7 PE=1 SV=2 CANONICAL=A0ABI0P701-1" }, "locus": { "chromosome": "18", "start_pos": 48504923, "end_pos": 48502628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087493.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087493.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058063.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058063.2" } ] } }, { "isoform_ac": "A0ABI0NT80-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P701/entry#A0ABI0NT80-1", "sequence": { "sequence": "MDVSLLSPPGSRKNVPHKTSLPEGIRVGTVLRIRGLVPDKAGRFYVNLLCGEEPGSDAALHFNPRLDESTVVFNTLERGTWGAEERGSGIPFQRGQPFDVLLIATEEGFKAVIADSEYHHFRYRIPPGRVRALEVGGDLQLELVKIF", "length": 147, "header": "tr|A0ABI0NT80-1|A0ABI0P701_BOVIN Computationally mapped isoform of Galectin OS=Bos taurus OX=9913 GN=LGALS7 PE=1 SV=1 CANONICAL=A0ABI0P701-1" }, "locus": { "chromosome": "18", "start_pos": 48505092, "end_pos": 48502628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144412.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144412.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107603.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107603.1" } ] } }, { "isoform_ac": "A0ABI0P1N0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P701/entry#A0ABI0P1N0-1", "sequence": { "sequence": "MSPWHLPDSGNEGDPGPGLGECVSRSPTGFWVPWDLGSMVSSPSPLFPWFYVNLLCGEEPGSDAALHFNPRLDESTVVFNTLERGTWGAEERGSGIPFQRGQPFDVLLIATEEGFKAVIADSEYHHFRYRIPPGRVRALEVGGDLQLELVKIF", "length": 153, "header": "tr|A0ABI0P1N0-1|A0ABI0P701_BOVIN Computationally mapped isoform of Galectin OS=Bos taurus OX=9913 GN=LGALS7 PE=1 SV=1 CANONICAL=A0ABI0P701-1" }, "locus": { "chromosome": "18", "start_pos": 48503806, "end_pos": 48502628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151812.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151812.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105151.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105151.1" } ] } }, { "isoform_ac": "A0ABI0P701-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P701/entry#A0ABI0P701-1", "sequence": { "sequence": "MAGSFNVPHKTSLPEGIRVGTVLRIRGLVPDKAGRFYVNLLCGEEPGSDAALHFNPRLDESTVVFNTLERGTWGAEERGSGIPFQRGQPFDVLLIATEEGFKAVIADSEYHHFRYRIPPGRVRALEVGGDLQLELVKIF", "length": 139, "header": "tr|A0ABI0P701-1|A0ABI0P701_BOVIN Isoform 1 of Galectin OS=Bos taurus OX=9913 GN=LGALS7 PE=1 SV=1 CANONICAL=A0ABI0P701-1" }, "locus": { "chromosome": "18", "start_pos": 48504743, "end_pos": 48502628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144729.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144729.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107387.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107387.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:787811", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787811", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P47929-1", "protein_name": "Galectin-7", "gene_name": "LGALS7B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNVPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNPRLDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF", "length": 136 }, "evidence": [ { "id": "A0ABI0P701", "url": "https://omabrowser.org/oma/group/A0ABI0P701/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97590-1", "protein_name": "Galectin-7", "gene_name": "Lgals7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSATHHKTPLPQGVRLGTVMRIRGVVPDQAGRFHVNLLCGEEQEADAALHFNPRLDTSEVVFNTKQQGKWGREERGTGIPFQRGQPFEVLIITTEEGFKTVIGDDEYLHFHHRMPSSNVRSVEVGGDVQLHSVKIF", "length": 136 }, "evidence": [ { "id": "A0ABI0P701", "url": "https://omabrowser.org/oma/group/A0ABI0P701/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P701", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P701" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P701", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P701" }, { "id": "PS51304", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51304" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Galectin", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 139, "start_aa": "His", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P5M2-1", "uniprot_ac": "A0ABI0P5M2", "uniprot_id": "A0ABI0P5M2_BOVIN", "mass": { "chemical_mass": 67472.0, "monoisotopic_mass": 67472.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC120", "type": "recommended", "evidence": [ { "id": "A0ABI0P5M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 120", "type": "synonym", "evidence": [ { "id": "A0ABI0P5M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5M2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC120", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2", "locus": { "chromosome": "X", "start_pos": 87152940, "end_pos": 87145113, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002561", "url": "https://www.ensembl.org/id/ENSBTAG00000002561" } ] } } ], "crossref": [ { "id": "ENSBTAG00000002561", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002561", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "508704", "url": "https://www.ncbi.nlm.nih.gov/gene/508704", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043447", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043447", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3S5ZPH5", "url": "https://www.orthodb.org/?gene=A0A3S5ZPH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MZL0", "url": "https://www.orthodb.org/?gene=G3MZL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16093", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16093", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16093:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16093:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11819", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11819", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3S5ZPH5", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3S5ZPH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5M2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5M2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZL0", "url": "https://www.uniprot.org/uniprotkb/G3MZL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZL0-1", "url": "https://www.uniprot.org/uniprotkb/G3MZL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVKGQLISSPTFNASAALFGEAAPQMKSERLRSLLDRQRALQEALSLKLQELRKVCLQEAELTGQLPPECPLEPGERPQLVRRRPPAARAYPPPHPNPAHHSLCPTEELALEALEREVSVQQQIAAAARRLALAPELSAEQRRRRRQVQADALRRLHELEEQLGEVRARLGLSGLPPSQPLPLSTGGAVITTQGVCLGTRLAQLSHEDVVLHSESSSLSESGASHDNEEPRGCFPLAERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKGRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSSSQDSQMGFPRVDPVSDRTSLFAARTRRSNSSEALLVDRAAGGGAGSPPAPMVPPASGPPVCKSSEVLYERPQPTPAFSSRTAGLPDPPRAARPSSAAPASRGAPRLPPVCGDFLLDYSLDRGLPRGGGGTGWGELLPAAEVPGPLSRRDGLVAMLPGPPPVYAADGSSPLLRSKDPHSRAPRTKPCGLPLEAAEGLEAHPNPVLWMPPPARIPTAGERSGHKNLALEGLRDWYIRNSGLASGPQRRPGLPHMGPQHPPFLHARCYEVGQALYGAPSQAPLPHSRSFTAPPVSGRYGGCFY", "length": 631, "header": "tr|A0ABI0P5M2-1|A0ABI0P5M2_BOVIN Isoform 1 of Coiled-coil domain containing 120 OS=Bos taurus OX=9913 GN=CCDC120 PE=4 SV=1 CANONICAL=A0ABI0P5M2-1" }, "isoforms": [ { "isoform_ac": "A0A3S5ZPH5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2/entry#A0A3S5ZPH5-1", "sequence": { "sequence": "MPEILITFSVLIKARLLTVAHGPLTRCCKSAQLPTCSAPTQWEGNQGTRALTLAQILRGQAKQALCSHQSRHPDSFRMEVKGQLISSPTFNASAALFGEAAPQMKSERLRSLLDRQRALQEALSLKLQELRKVCLQEAELTGQLPPECPLEPGERPQLVRRRPPAARAYPPPHPNPAHHSLCPTEELALEALEREVSVQQQIAAAARRLALAPELSAEQRRRRRQVQADALRRLHELEEQLGEVRARLGLSGLPPSQPLPLSTGGAVITTQGVCLGTRLAQLSHEDVVLHSESSSLSESGASHDNEEPRGCFPLAERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKGRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSSSQDSQMGFPRVDPVSDRTSLFAARTRRSNSSEALLVDRAAGGGAGSPPAPMVPPASGPPVCKSSEVLYERPQPTPAFSSRTAGLPDPPRAARPSSAAPASRGAPRLPPVCGDFLLDYSLDRGLPRGGGGTGWGELLPAAEVPGPLSRRDGLVAMLPGPPPVYAADGSSPLLRSKDPHSRAPRTKPCGLPLEAAEGLEAHPNPVLWMPPPARIPTAGERSGHKNLALEGLRDWYIRNSGLASGPQRRPGLPHMGPQHPPFLHARCYEVGQALYGAPSQAPLPHSRSFTAPPVSGRYGGCFY", "length": 708, "header": "tr|A0A3S5ZPH5-1|A0ABI0P5M2_BOVIN Computationally mapped isoform of Coiled-coil domain containing 120 OS=Bos taurus OX=9913 GN=CCDC120 PE=4 SV=2 CANONICAL=A0ABI0P5M2-1" }, "locus": { "chromosome": "X", "start_pos": 87151295, "end_pos": 87145154, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003317.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003317.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003317.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003317.6" } ] } }, { "isoform_ac": "A0ABI0P5M2-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2/entry#A0ABI0P5M2-1", "sequence": { "sequence": "MEVKGQLISSPTFNASAALFGEAAPQMKSERLRSLLDRQRALQEALSLKLQELRKVCLQEAELTGQLPPECPLEPGERPQLVRRRPPAARAYPPPHPNPAHHSLCPTEELALEALEREVSVQQQIAAAARRLALAPELSAEQRRRRRQVQADALRRLHELEEQLGEVRARLGLSGLPPSQPLPLSTGGAVITTQGVCLGTRLAQLSHEDVVLHSESSSLSESGASHDNEEPRGCFPLAERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKGRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSSSQDSQMGFPRVDPVSDRTSLFAARTRRSNSSEALLVDRAAGGGAGSPPAPMVPPASGPPVCKSSEVLYERPQPTPAFSSRTAGLPDPPRAARPSSAAPASRGAPRLPPVCGDFLLDYSLDRGLPRGGGGTGWGELLPAAEVPGPLSRRDGLVAMLPGPPPVYAADGSSPLLRSKDPHSRAPRTKPCGLPLEAAEGLEAHPNPVLWMPPPARIPTAGERSGHKNLALEGLRDWYIRNSGLASGPQRRPGLPHMGPQHPPFLHARCYEVGQALYGAPSQAPLPHSRSFTAPPVSGRYGGCFY", "length": 631, "header": "tr|A0ABI0P5M2-1|A0ABI0P5M2_BOVIN Isoform 1 of Coiled-coil domain containing 120 OS=Bos taurus OX=9913 GN=CCDC120 PE=4 SV=1 CANONICAL=A0ABI0P5M2-1" }, "locus": { "chromosome": "X", "start_pos": 87151295, "end_pos": 87145951, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138157.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138157.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106908.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106908.1" } ] } }, { "isoform_ac": "G3MZL0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2/entry#G3MZL0-1", "sequence": { "sequence": "MGREPRYPGLDIGTDSERALCSHQSRHPDSFRMEVKGQLISSPTFNASAALFGEAAPQMKSERLRSLLDRQRALQEALSLKLQELRKVCLQEAELTGQLPPECPLEPGERPQLVRRRPPAARAYPPPHPNPAHHSLCPTEELALEALEREVSVQQQIAAAARRLALAPELSAEQRRRRRQVQADALRRLHELEEQLGEVRARLGLSGLPPSQPLPLSTGGAVITTQGVCLGTRLAQLSHEDVVLHSESSSLSESGASHDNEEPRGCFPLAERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKGRRNSVASPTSPTRSLPRSASSFEGRSVPATPVLTRGAGPQLCKPEGLHSRQWSSSQDSQMGFPRVDPVSDRTSLFAARTRRSNSSEALLVDRAAGGGAGSPPAPMVPPASGPPVCKSSEVLYERPQPTPAFSSRTAGLPDPPRAARPSSAAPASRGAPRLPPVCGDFLLDYSLDRGLPRGGGGTGWGELLPAAEVPGPLSRRDGLVAMLPGPPPVYAADGSSPLLRSKDPHSRAPRTKPCGLPLEAAEGLEAHPNPVLWMPPPARIPTAGERSGHKNLALEGLRDWYIRNSGLASGPQRRPGLPHMGPQHPPFLHARCYEVGQALYGAPSQAPLPHSRSFTAPPVSGRYYADFLYPPELSARLSDLTLEGEQSSGSDPQTPGTLV", "length": 694, "header": "tr|G3MZL0-1|A0ABI0P5M2_BOVIN Computationally mapped isoform of Coiled-coil domain containing 120 OS=Bos taurus OX=9913 GN=CCDC120 PE=4 SV=3 CANONICAL=A0ABI0P5M2-1" }, "locus": { "chromosome": "X", "start_pos": 87151879, "end_pos": 87145727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065422.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065422.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055010.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055010.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5M2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5M2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2" } ], "pmid": "" }, { "name": "centriolar subdistal appendage", "id": "GO:0120103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120103", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5M2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5M2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2" } ], "pmid": "" }, { "name": "microtubule anchoring at centrosome", "id": "GO:0034454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034454", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5M2", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P5M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M2" }, { "id": "PF11819", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11819" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytohesin Ubiquitin Protein Inducing", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 140, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 360, "end_pos": 362 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F6QLQ6-1", "uniprot_ac": "F6QLQ6", "uniprot_id": "F6QLQ6_BOVIN", "mass": { "chemical_mass": 19770.0, "monoisotopic_mass": 19770.0 }, "refseq": {}, "gene_names": [ { "name": "CMTM7", "type": "recommended", "evidence": [ { "id": "F6QLQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QLQ6" } ] } ], "protein_names": [ { "name": "CKLF like MARVEL transmembrane domain containing 7", "type": "synonym", "evidence": [ { "id": "F6QLQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QLQ6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QLQ6", "url": "https://www.uniprot.org/uniprotkb/F6QLQ6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CMTM7", "url": "https://www.uniprot.org/uniprotkb/F6QLQ6", "locus": { "chromosome": "22", "start_pos": 6870608, "end_pos": 6821833, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001712", "url": "https://www.ensembl.org/id/ENSBTAG00000001712" } ] } } ], "crossref": [ { "id": "ENSBTAG00000001712", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001712", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "532269", "url": "https://www.ncbi.nlm.nih.gov/gene/532269", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532269", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532269", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FEVVTIW", "url": "https://omabrowser.org/oma/group/FEVVTIW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR22776", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22776", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22776:SF89", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22776:SF89", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9RZ54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZ54-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE67", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE67-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYK8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYK8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QLQ6", "url": "https://www.uniprot.org/uniprotkb/F6QLQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QLQ6-1", "url": "https://www.uniprot.org/uniprotkb/F6QLQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHGAGLVRTTCSSGSAPGDGVGAGPLGSSSSVRLLDPVYPRTQAAMLKVAQMATLLIAFICVRSSLWTSYSAYSYFEVVTICNLIMILAFYLAHLFRLPRVLTCISWPLSELLHYLIGTLLLLIASIVAASKSYSQSGLVAGAVRTFPRRRQGGIPILNAHFLPHRAANGLFSGAFLSQDQSPP", "length": 185, "header": "tr|F6QLQ6-1|F6QLQ6_BOVIN Isoform 1 of CKLF like MARVEL transmembrane domain containing 7 OS=Bos taurus OX=9913 GN=CMTM7 PE=4 SV=1 CANONICAL=F6QLQ6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RZ54-1", "url": "https://www.uniprot.org/uniprotkb/F6QLQ6/entry#A0AAA9RZ54-1", "sequence": { "sequence": "MSHGAGLVRTTCSSGSAPGDGVGAGPLGSSSSVRLLDPVYPRTQAAMLKVAQMATLLIAFICVRSSLWTSYSAYSYFEVVTICNLIMILAFYLAHLFRLPRVLTCISWPLSELLHYLIGTLLLLIASIVAASKSYSQSGLVAGAVFGFLATFLCLASVWLSYKISCVTQSTAMQDLLSKAPK", "length": 182, "header": "tr|A0AAA9RZ54-1|F6QLQ6_BOVIN Computationally mapped isoform of CKLF like MARVEL transmembrane domain containing 7 OS=Bos taurus OX=9913 GN=CMTM7 PE=4 SV=1 CANONICAL=F6QLQ6-1" }, "locus": { "chromosome": "22", "start_pos": 6870465, "end_pos": 6821856, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117079.2", "url": "https://www.ensembl.org/id/ENSBTAT00000117079.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076412.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076412.1" } ] } }, { "isoform_ac": "A0AAA9TE67-1", "url": "https://www.uniprot.org/uniprotkb/F6QLQ6/entry#A0AAA9TE67-1", "sequence": { "sequence": "MSHGAGLVRTTCSSGSAPGDGVGAGPLGSSSSVRLLDPVYPRTQAAMLKVAQMATLLIAFICVRSSLWTSYSAYSYFEVVTICNLIMILAFYLAHLFRLPRVLTCISWPLSELLHYLIGTLLLLIASIVAASKSYSQSGLVAGAVFGFLATFLCLASVWLSYKISCVTQSTAPCASLVV", "length": 179, "header": "tr|A0AAA9TE67-1|F6QLQ6_BOVIN Computationally mapped isoform of CKLF like MARVEL transmembrane domain containing 7 OS=Bos taurus OX=9913 GN=CMTM7 PE=4 SV=2 CANONICAL=F6QLQ6-1" }, "locus": { "chromosome": "22", "start_pos": 6946085, "end_pos": 6821856, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124641.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124641.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096449.2", "url": "https://www.ensembl.org/id/ENSBTAP00000096449.2" } ] } }, { "isoform_ac": "A0AAA9TYK8-1", "url": "https://www.uniprot.org/uniprotkb/F6QLQ6/entry#A0AAA9TYK8-1", "sequence": { "sequence": "MSHGAGLVRTTCSSGSAPGDGVGAGPLGSSSSVRLLDPVYPRTQAAMLKVAQMATLLIAFICVRSSLWTSYSAYSYFEVVTICNLIMILAFYLAHLFRLPRVLTCISWPLSELLHYLIGTLLLLIASIVAASKSYSQSGLVAGADSWEARQNRKPLWMKCI", "length": 161, "header": "tr|A0AAA9TYK8-1|F6QLQ6_BOVIN Computationally mapped isoform of CKLF like MARVEL transmembrane domain containing 7 OS=Bos taurus OX=9913 GN=CMTM7 PE=4 SV=1 CANONICAL=F6QLQ6-1" }, "locus": { "chromosome": "22", "start_pos": 6867078, "end_pos": 6821856, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103700.2", "url": "https://www.ensembl.org/id/ENSBTAT00000103700.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103707.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103707.1" } ] } }, { "isoform_ac": "F6QLQ6-1", "url": "https://www.uniprot.org/uniprotkb/F6QLQ6/entry#F6QLQ6-1", "sequence": { "sequence": "MSHGAGLVRTTCSSGSAPGDGVGAGPLGSSSSVRLLDPVYPRTQAAMLKVAQMATLLIAFICVRSSLWTSYSAYSYFEVVTICNLIMILAFYLAHLFRLPRVLTCISWPLSELLHYLIGTLLLLIASIVAASKSYSQSGLVAGAVRTFPRRRQGGIPILNAHFLPHRAANGLFSGAFLSQDQSPP", "length": 185, "header": "tr|F6QLQ6-1|F6QLQ6_BOVIN Isoform 1 of CKLF like MARVEL transmembrane domain containing 7 OS=Bos taurus OX=9913 GN=CMTM7 PE=4 SV=1 CANONICAL=F6QLQ6-1" }, "locus": { "chromosome": "22", "start_pos": 6863983, "end_pos": 6821856, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002243.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002243.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002243.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002243.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:532269", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532269", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6QLQ6", "url": "https://www.uniprot.org/uniprotkb/F6QLQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QLQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QLQ6" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 166, "start_aa": "Tyr", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P658-1", "uniprot_ac": "A0ABI0P658", "uniprot_id": "A0ABI0P658_BOVIN", "mass": { "chemical_mass": 84570.0, "monoisotopic_mass": 84570.0 }, "refseq": { "ac": "XP_002686866", "name": "protein C-mannosyl-transferase DPY19L1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686866" }, "gene_names": [ { "name": "DPY19L1", "type": "recommended", "evidence": [ { "id": "A0ABI0P658", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P658" } ] }, { "name": "DPY19L1", "type": "synonym", "evidence": [ { "id": "XP_002686866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686866" } ] } ], "protein_names": [ { "name": "Dpy-19 like C-mannosyltransferase 1", "type": "synonym", "evidence": [ { "id": "A0ABI0P658", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P658/entry#names_and_taxonomy" } ] }, { "name": "protein C-mannosyl-transferase DPY19L1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002686866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686866" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P658", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P658" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DPY19L1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P658", "locus": { "chromosome": "4", "start_pos": 62067227, "end_pos": 61976215, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005785", "url": "https://www.ensembl.org/id/ENSBTAG00000005785" } ] } } ], "crossref": [ { "id": "ENSBTAG00000005785", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005785", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20178", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20178", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "536508", "url": "https://www.ncbi.nlm.nih.gov/gene/536508", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047463", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047463", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:536508", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536508", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1N3H6", "url": "https://www.orthodb.org/?gene=F1N3H6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31488", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31488", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31488:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31488:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002686866", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686866", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S5R5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5R5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5R5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5R5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1P3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1P3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P658", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P658", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P658-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P658-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3H6", "url": "https://www.uniprot.org/uniprotkb/F1N3H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3H6-1", "url": "https://www.uniprot.org/uniprotkb/F1N3H6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLQARNKHREAAPKPPQPPRASQSPLRGSPDVGAGEPGPERAPPSPRRKGAAGRKGPRAESAAPPAGGGLGGRLAAGLRGALGLRRSGRGRTWTTLLLAAFAAVLHWSHITHLFENDRHFSHLSTLEREMAFRTEMGLYYSYFKTIVEAPSFLNGVWMIMNDKLTEYPLVINTLKRFNLYPEVILASWYRIYTKIMDLIGIQTKICWTVTRGEGLSPIESCEGLGDPACFYVAVIFILNGLMMALFFIYGTYLSGSRLGGLVTVLCFFFNHGECTRVMWTPPLRESFSYPFLVLQMLLVTHILRATKLYRGSLIALCISNVFFMLPWQFAQFVLLTQIASLFALYVVGYIDISKLRKIIYIHMISLALCFVLMFGNSMLLTSYYASSLVIIWGLLAMKPYFLKINVSELSLWVIQGCFWLFGTVILKYLTSKIFGIADDAHIGNLLTSKFFSYKDFDTLLYTCAAEFDFMEKETPLRYTKTLLLPVVLVVFIVIIRKVISDMWVVLTKQQTHIRKHQFDHGELVYHALQLLAYTVLGVLIMRLKLFLTPHMCVMASLICSRQLFGWLFCKVHPGAVVFAVLAAMSIQGSANLQTQWNIVGEFSNLPQEELIEWIKYSTKPDAVFAGAMPTMASVKLSALRPVVNHPHYEDAGLRARTKIVYSMYSRKAAEEVKRELIKLQVNYYILEESWCIRRSKPGCSMPEIWDVEDPANAGKPPLCNLLVKESKPHFTTVFQNSVYKVLEVIEE", "length": 748, "header": "tr|A0ABI0P658-1|A0ABI0P658_BOVIN Isoform 1 of Dpy-19 like C-mannosyltransferase 1 OS=Bos taurus OX=9913 GN=DPY19L1 PE=3 SV=1 CANONICAL=A0ABI0P658-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S5R5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P658/entry#A0AAA9S5R5-1", "sequence": { "sequence": "MVLQARNKHREAAPKPPQPPRASQSPLRGSPDVGAGEPGPERAPPSPRRKGAAGRKGPRAESAAPPAGGGLGGRLAAGLRGALGLRRSGRGRTWTTLLLAAFAAVLHWSHITHLFENDRHFSHLSTLEREMAFRTEMGLYYSYFKTIVEAPSFLNGVWMIMNDKLTEYPLVINTLKRFNLYPEVILASWYRIYTKIMDLIGIQTKICWTVTRGEGLSPIESCEGLGDPACFYVAVIFILNGLMMALFFIYGTYLSGSRLGGLVTVLCFFFNHGECTRVMWTPPLRESFSYPFLVLQMLLVTHILRATKLYRGSLIALCISNVFFMLPWQFAQFVLLTQIASLFALYVVGYIDISKLRKIIYIHMISLALCFVLMFGNSMLLTSYYASSLVIIWGLLAMKPYFLKINVSELSLWVIQGCFWLFGTVILKYLTSKIFGIADDTPLRYTKTLLLPVVLVVFIVIIRKVISDMWVVLTKQQTHIRKHQFDHGELVYHALQLLAYTVLGVLIMRLKLFLTPHMCVMASLICSRQLFGWLFCKVHPGAVVFAVLAAMSIQGSANLQTQWNIVGEFSNLPQEELIEWIKYSTKPDAVFAGAMPTMASVKLSALRPVVNHPHYEDAGLRARTKIVYSMYSRKAAEEVKRELIKLQVNYYILEESWCIRRSKPGCSMPEIWDVEDPANAGKPPLCNLLVKESKPHFTTVFQNSVYKVLEVIEE", "length": 714, "header": "tr|A0AAA9S5R5-1|A0ABI0P658_BOVIN Computationally mapped isoform of Dpy-19 like C-mannosyltransferase 1 OS=Bos taurus OX=9913 GN=DPY19L1 PE=3 SV=1 CANONICAL=A0ABI0P658-1" }, "locus": { "chromosome": "4", "start_pos": 62066223, "end_pos": 61976414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127047.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127047.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080553.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080553.1" } ] } }, { "isoform_ac": "A0ABI0P1P3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P658/entry#A0ABI0P1P3-1", "sequence": { "sequence": "MEDAAFAAVLHWSHITHLFENDRHFSHLSTLEREMAFRTEMGLYYSYFKTIVEAPSFLNGVWMIMNDKLTEYPLVINTLKRFNLYPEVILASWYRIYTKIMDLIGIQTKICWTVTRGEGLSPIESCEGLGDPACFYVAVIFILNGLMMALFFIYGTYLSGSRLGGLVTVLCFFFNHGECTRVMWTPPLRESFSYPFLVLQMLLVTHILRATKLYRGSLIALCISNVFFMLPWQFAQFVLLTQIASLFALYVVGYIDISKLRKIIYIHMISLALCFVLMFGNSMLLTSYYASSLVIIWGLLAMKPYFLKINVSELSLWVIQGCFWLFGTVILKYLTSKIFGIADDAHIGNLLTSKFFSYKDFDTLLYTCAAEFDFMEKETPLRYTKTLLLPVVLVVFIVIIRKVISDMWVVLTKQQTHIRKHQFDHGELVYHALQLLAYTVLGVLIMRLKLFLTPHMCVMASLICSRQLFGWLFCKVHPGAVVFAVLAAMSIQGSANLQTQWNIVGEFSNLPQEELIEWIKYSTKPDAVFAGAMPTMASVKLSALRPVVNHPHYEDAGLRARTKIVYSMYSRKAAEEVKRELIKLQVNYYILEESWCIRRSKPGCSMPEIWDVEDPANAGKPPLCNLLVKESKPHFTTVFQNSVYKVLEVIEE", "length": 652, "header": "tr|A0ABI0P1P3-1|A0ABI0P658_BOVIN Computationally mapped isoform of Dpy-19 like C-mannosyltransferase 1 OS=Bos taurus OX=9913 GN=DPY19L1 PE=3 SV=1 CANONICAL=A0ABI0P658-1" }, "locus": { "chromosome": "4", "start_pos": 62066223, "end_pos": 61973912, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138626.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138626.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104240.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104240.1" } ] } }, { "isoform_ac": "A0ABI0P658-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P658/entry#A0ABI0P658-1", "sequence": { "sequence": "MVLQARNKHREAAPKPPQPPRASQSPLRGSPDVGAGEPGPERAPPSPRRKGAAGRKGPRAESAAPPAGGGLGGRLAAGLRGALGLRRSGRGRTWTTLLLAAFAAVLHWSHITHLFENDRHFSHLSTLEREMAFRTEMGLYYSYFKTIVEAPSFLNGVWMIMNDKLTEYPLVINTLKRFNLYPEVILASWYRIYTKIMDLIGIQTKICWTVTRGEGLSPIESCEGLGDPACFYVAVIFILNGLMMALFFIYGTYLSGSRLGGLVTVLCFFFNHGECTRVMWTPPLRESFSYPFLVLQMLLVTHILRATKLYRGSLIALCISNVFFMLPWQFAQFVLLTQIASLFALYVVGYIDISKLRKIIYIHMISLALCFVLMFGNSMLLTSYYASSLVIIWGLLAMKPYFLKINVSELSLWVIQGCFWLFGTVILKYLTSKIFGIADDAHIGNLLTSKFFSYKDFDTLLYTCAAEFDFMEKETPLRYTKTLLLPVVLVVFIVIIRKVISDMWVVLTKQQTHIRKHQFDHGELVYHALQLLAYTVLGVLIMRLKLFLTPHMCVMASLICSRQLFGWLFCKVHPGAVVFAVLAAMSIQGSANLQTQWNIVGEFSNLPQEELIEWIKYSTKPDAVFAGAMPTMASVKLSALRPVVNHPHYEDAGLRARTKIVYSMYSRKAAEEVKRELIKLQVNYYILEESWCIRRSKPGCSMPEIWDVEDPANAGKPPLCNLLVKESKPHFTTVFQNSVYKVLEVIEE", "length": 748, "header": "tr|A0ABI0P658-1|A0ABI0P658_BOVIN Isoform 1 of Dpy-19 like C-mannosyltransferase 1 OS=Bos taurus OX=9913 GN=DPY19L1 PE=3 SV=1 CANONICAL=A0ABI0P658-1" }, "locus": { "chromosome": "4", "start_pos": 62066223, "end_pos": 61976414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152119.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152119.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107054.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107054.1" } ] } }, { "isoform_ac": "F1N3H6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P658/entry#F1N3H6-1", "sequence": { "sequence": "MVLQARNKHREAAPKPPQPPRASQSPLRGSPDVGAGEPGPERAPPSPRRKGAAGRKGPRAESAAPPAGGGLGGRLAAGLRGALGLRRSGRGRTWTTLLLAAFAAVLHWSHITHLFENDRHFSHLSTLEREMAFRTEMGLYYSYFKTIVEAPSFLNGVWMIMNDKLTEYPLVINTLKRFNLYPEVILASWYRIYTKIMDLIGIQTKICWTVTRGEGLSPIESCEGLGDPACFYVAVIFILNGLMMALFFIYGTYLSGSRLGGLVTVLCFFFNHGECTRVMWTPPLRESFSYPFLVLQMLLVTHILRATKLYRGSLIALCISNVFFMLPWQFAQFVLLTQIASLFALYVVGYIDISKLRKIIYIHMGPCCIIYEGVLKKIQKPNRKMDIRSRKFIHTQNNISLALCFVLMFGNSMLLTSYYASSLVIIWGLLAMKPYFLKINVSELSLWVIQGCFWLFGTVILKYLTSKIFGIADDAHIGNLLTSKFFSYKDFDTLLYTCAAEFDFMEKETPLRYTKTLLLPVVLVVFIVIIRKVISDMWVVLTKQQTHIRKHQFDHGELVYHALQLLAYTVLGVLIMRLKLFLTPHMCVMASLICSRQLFGWLFCKVHPGAVVFAVLAAMSIQGSANLQTQWNIVGEFSNLPQEELIEWIKYSTKPDAVFAGAMPTMASVKLSALRPVVNHPHYEDAGLRARTKIVYSMYSRKAAEEVKRELIKLQVNYYILEESWCIRRSKPGCSMPEIWDVEDPANAGKPPLCNLLVKESKPHFTTVFQNSVYKVLEVIEE", "length": 782, "header": "tr|F1N3H6-1|A0ABI0P658_BOVIN Computationally mapped isoform of Dpy-19 like C-mannosyltransferase 1 OS=Bos taurus OX=9913 GN=DPY19L1 PE=3 SV=4 CANONICAL=A0ABI0P658-1" }, "locus": { "chromosome": "4", "start_pos": 62066223, "end_pos": 61976414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007607.8", "url": "https://www.ensembl.org/id/ENSBTAT00000007607.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007607.7", "url": "https://www.ensembl.org/id/ENSBTAP00000007607.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:536508", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536508", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P658", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P658" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P658", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P658" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P658", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P658" } ], "pmid": "" }, { "name": "mannosyltransferase activity", "id": "GO:0000030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000030", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P658", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P658" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein C-linked glycosylation", "id": "GO:0018103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018103", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P658", "url": 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"https://www.uniprot.org/uniprotkb/A0ABI0P7K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P7K4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2U8", "url": "https://www.uniprot.org/uniprotkb/F1N2U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2U8-1", "url": "https://www.uniprot.org/uniprotkb/F1N2U8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNLKPDGEHSTGAGTGTGTGTGSGGTLEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTSRQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKNKLMATPNPTNAHPTLGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHTAFTYPAATAAAAALHAQVRWYPSSDTTQPGWKYRQFC", "length": 211, "header": "tr|A0ABI0P7K4-1|A0ABI0P7K4_BOVIN Isoform 1 of RNA binding protein, mRNA processing factor 2 OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P7K4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T4J1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4/entry#A0AAA9T4J1-1", "sequence": { "sequence": "GQRGEVISSRSRSRLRLARAEAQVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTSRQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKNKLMATPNPTNAHPTLGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHTAFTYPAATAAAAALHAQVRWYPSSDTTQPGWKYRQFC", "length": 203, "header": "tr|A0AAA9T4J1-1|A0ABI0P7K4_BOVIN Computationally mapped isoform of RNA binding protein, mRNA processing factor 2 OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P7K4-1" }, "locus": { "chromosome": "10", "start_pos": 45337960, "end_pos": 45312273, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114506.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114506.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092728.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092728.1" } ] } }, { "isoform_ac": "A0AAA9TT78-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4/entry#A0AAA9TT78-1", "sequence": { "sequence": "MSNLKPDGEHSTGAGTGTGTGTGSGGTLEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTSRQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKNKLMATPNPTNAHPTLGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHTAFTYPAATAAAAALHAQVTSEARGLFVPELLSPWPPWEWDEGHLKGWWLFSGGA", "length": 228, "header": "tr|A0AAA9TT78-1|A0ABI0P7K4_BOVIN Computationally mapped isoform of RNA binding protein, mRNA processing factor 2 OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P7K4-1" }, "locus": { "chromosome": "10", "start_pos": 45333447, "end_pos": 45313293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113571.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113571.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100543.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100543.1" } ] } }, { "isoform_ac": "A0AAA9TV34-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4/entry#A0AAA9TV34-1", "sequence": { "sequence": "MSNLKPDGEHSTGAGTGTGTGTGSGGTLEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTSRQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKNKLMATPNPTNAHPTLGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHTAFTYPAATAAAAALHAQVTSPLGLHVVLICKTRGQDQIGWRASAPVCSEMLGHDHTRQSLGARTVRMSDYSGATWLPFQGGAPAG", "length": 259, "header": "tr|A0AAA9TV34-1|A0ABI0P7K4_BOVIN Computationally mapped isoform of RNA binding protein, mRNA processing factor 2 OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P7K4-1" }, "locus": { "chromosome": "10", "start_pos": 45332824, "end_pos": 45313293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122638.2", "url": "https://www.ensembl.org/id/ENSBTAT00000122638.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100987.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100987.1" } ] } }, { "isoform_ac": "A0AAA9TWF7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4/entry#A0AAA9TWF7-1", "sequence": { "sequence": "MSNLKPDGEHSTGAGTGTGTGTGSGGTLEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTSRQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKNKLMATPNPTNAHPTLGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHTAFTYPAATAAAAALHAQVGVSHVPTTAVPHPRGPECPSSLGQVARDPDVPSAECPGISEEPAPTSC", "length": 240, "header": "tr|A0AAA9TWF7-1|A0ABI0P7K4_BOVIN Computationally mapped isoform of RNA binding protein, mRNA processing factor 2 OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P7K4-1" }, "locus": { "chromosome": "10", "start_pos": 45336368, "end_pos": 45313293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128253.2", "url": "https://www.ensembl.org/id/ENSBTAT00000128253.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101512.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101512.1" } ] } }, { "isoform_ac": "A0AAA9U114-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4/entry#A0AAA9U114-1", "sequence": { "sequence": "MSNLKPDGEHSTGAGTGTGTGTGSGGTLEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTSRQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKNKLMATPNPTNAHPTLGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHTAFTYPAATAAAAALHAQARTNIWESYPLETTRTLVSNEFLYSVLPDPCGHRVTLLLFSRSVASDCLQPHGLQHARPPCPPLFPRVY", "length": 260, "header": "tr|A0AAA9U114-1|A0ABI0P7K4_BOVIN Computationally mapped isoform of RNA binding protein, mRNA processing factor 2 OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P7K4-1" }, "locus": { "chromosome": "10", "start_pos": 45337435, "end_pos": 45313293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103510.2", "url": "https://www.ensembl.org/id/ENSBTAT00000103510.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103410.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103410.1" } ] } }, { "isoform_ac": "A0ABI0P5F3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4/entry#A0ABI0P5F3-1", "sequence": { "sequence": "MWQNREAVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTSRQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKNKLMATPNPTNAHPTLGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHTAFTYPAATAAAAALHAQVRWYPSSDTTQPGWKYRQFC", "length": 187, "header": "tr|A0ABI0P5F3-1|A0ABI0P5F3_BOVIN Computationally mapped isoform of RNA binding protein, mRNA processing factor 2 OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P7K4-1" }, "locus": { "chromosome": "10", "start_pos": 45337960, "end_pos": 45314160, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149617.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149617.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106800.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106800.1" } ] } }, { "isoform_ac": "A0ABI0P7K4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4/entry#A0ABI0P7K4-1", "sequence": { "sequence": "MSNLKPDGEHSTGAGTGTGTGTGSGGTLEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTSRQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKNKLMATPNPTNAHPTLGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHTAFTYPAATAAAAALHAQVRWYPSSDTTQPGWKYRQFC", "length": 211, "header": "tr|A0ABI0P7K4-1|A0ABI0P7K4_BOVIN Isoform 1 of RNA binding protein, mRNA processing factor 2 OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0ABI0P7K4-1" }, "locus": { "chromosome": "10", "start_pos": 45337960, "end_pos": 45313293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150135.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150135.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107200.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107200.1" } ] } }, { "isoform_ac": "F1N2U8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4/entry#F1N2U8-1", "sequence": { "sequence": "MSNLKPDGEHSTGAGTGTGTGTGSGGTLEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTSRQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKNKLMATPNPTNAHPTLGAHFIARDPYDLMGAALIPASPEAWAPYPLYTTELTPAISHTAFTYPAATAAAAALHAQGEERISCEATFRLRC", "length": 206, "header": "tr|F1N2U8-1|A0ABI0P7K4_BOVIN Computationally mapped isoform of RNA binding protein, mRNA processing factor 2 OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=A0ABI0P7K4-1" }, "locus": { "chromosome": "10", "start_pos": 45331491, "end_pos": 45313293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014659.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014659.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014659.6", "url": "https://www.ensembl.org/id/ENSBTAP00000014659.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P7K4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P7K4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P7K4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P7K4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P7K4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P7K4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P7K4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of smooth muscle cell differentiation", "id": "GO:0051151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051151", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P7K4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P7K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P7K4" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 110, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABZ3NNH1-1", "uniprot_ac": "A0ABZ3NNH1", "uniprot_id": "A0ABZ3NNH1_BOVIN", "mass": { "chemical_mass": 68280.0, "monoisotopic_mass": 68280.0 }, "refseq": {}, "gene_names": [ { "name": "MTF2", "type": "recommended", "evidence": [ { "id": "A0ABZ3NNH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1" } ] } ], "protein_names": [ { "name": "Metal-response element-binding transcription factor 2", "type": "recommended", "evidence": [ { "id": "A0ABZ3NNH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1/entry#names_and_taxonomy" } ] }, { "name": "Metal regulatory transcription factor 2", "type": "synonym", "evidence": [ { "id": "A0ABZ3NNH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Polycomb group (PcG) protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity. Regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation. Promotes recruitment of the PRC2 complex to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells. Required to repress Hox genes by enhancing H3K27me3 methylation of the PRC2 complex. In some conditions may act as an inhibitor of PRC2 activity: able to activate the CDKN2A gene and promote cellular senescence by suppressing the catalytic activity of the PRC2 complex locally. Binds to the metal-regulating-element (MRE) of MT1A gene promoter.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9T8L1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8L1#function" }, { "database": "UniProtKB", "id": "ARBA00058935", "url": "https://www.uniprot.org/uniprotkb/ARBA00058935#function" }, { "database": "UniProtKB", "id": "A0ABZ3NNH1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1#function" }, { "database": "UniProtKB", "id": "A0ABI0NP00", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP00#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNH1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MTF2", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1", "locus": { "chromosome": "3", "start_pos": 50331720, "end_pos": 50352264, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001393", "url": "https://www.ensembl.org/id/ENSBTAG00000001393" } ] } } ], "crossref": [ { "id": "ENSBTAG00000001393", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001393", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15578", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15578", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15580", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15580", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20450", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20450", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:615211", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615211", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR12628", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12628", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12628:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12628:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9T8L1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8L1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8L1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NP00", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NP00-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NP00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABZ3NNH1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABZ3NNH1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAQGDPSVHPGCRDSTGAGNSLVHKRSPLRRNQKTPTSLTKLSLQDGHKVKKPACKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPISESREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPPLDKESISENPSLDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS", "length": 605, "header": "tr|A0ABZ3NNH1-1|A0ABZ3NNH1_BOVIN Isoform 1 of Metal-response element-binding transcription factor 2 OS=Bos taurus OX=9913 GN=MTF2 PE=3 SV=1 CANONICAL=A0ABZ3NNH1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T8L1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1/entry#A0AAA9T8L1-1", "sequence": { "sequence": "MRDSTGAGNSLVHKRSPLRRNQKTPTSLTKLSLQDGHKVKKPACKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPISESREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPPLDKESISENPSLDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS", "length": 583, "header": "tr|A0AAA9T8L1-1|A0ABZ3NNH1_BOVIN Computationally mapped isoform of Metal-response element-binding transcription factor 2 OS=Bos taurus OX=9913 GN=MTF2 PE=3 SV=2 CANONICAL=A0ABZ3NNH1-1" }, "locus": { "chromosome": "3", "start_pos": 50402308, "end_pos": 50331983, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129889.2", "url": "https://www.ensembl.org/id/ENSBTAT00000129889.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095073.2", "url": "https://www.ensembl.org/id/ENSBTAP00000095073.2" } ] } }, { "isoform_ac": "A0ABI0NP00-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1/entry#A0ABI0NP00-1", "sequence": { "sequence": "MRDSTGAGNSLVHKRSPLRRNQKTPTSLTKLSLQDGHKVKKPACKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMEVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPPLDKESISENPSLDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS", "length": 536, "header": "tr|A0ABI0NP00-1|A0ABZ3NNH1_BOVIN Computationally mapped isoform of Metal-response element-binding transcription factor 2 OS=Bos taurus OX=9913 GN=MTF2 PE=3 SV=1 CANONICAL=A0ABZ3NNH1-1" }, "locus": { "chromosome": "3", "start_pos": 50402308, "end_pos": 50331983, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138705.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138705.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107529.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107529.1" } ] } }, { "isoform_ac": "A0ABZ3NNH1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1/entry#A0ABZ3NNH1-1", "sequence": { "sequence": "MEAQGDPSVHPGCRDSTGAGNSLVHKRSPLRRNQKTPTSLTKLSLQDGHKVKKPACKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPISESREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPPLDKESISENPSLDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS", "length": 605, "header": "tr|A0ABZ3NNH1-1|A0ABZ3NNH1_BOVIN Isoform 1 of Metal-response element-binding transcription factor 2 OS=Bos taurus OX=9913 GN=MTF2 PE=3 SV=1 CANONICAL=A0ABZ3NNH1-1" }, "locus": { "chromosome": "3", "start_pos": 50402218, "end_pos": 50331983, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001831.8", "url": "https://www.ensembl.org/id/ENSBTAT00000001831.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001831.6", "url": "https://www.ensembl.org/id/ENSBTAP00000001831.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:615211", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615211", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNH1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNH1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0ABZ3NNH1", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABZ3NNH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABZ3NNH1" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 169, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 288, "end_pos": 290 }, { "start_pos": 462, "end_pos": 464 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P6M9-1", "uniprot_ac": "A0ABI0P6M9", "uniprot_id": "A0ABI0P6M9_BOVIN", "mass": { "chemical_mass": 38672.0, "monoisotopic_mass": 38672.0 }, "refseq": { "ac": "XP_059737223", "name": "SAGA-associated factor 29 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059737223" }, "gene_names": [ { "name": "SGF29", "type": "recommended", "evidence": [ { "id": "A0ABI0P6M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9" } ] }, { "name": "CCDC101", "type": "synonym", "evidence": [ { "id": "XP_059737223", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059737223" } ] }, { "name": "SGF29", "type": "synonym", "evidence": [ { "id": "XP_059737223", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059737223" } ] } ], "protein_names": [ { "name": "SAGA-associated factor 29", "type": "recommended", "evidence": [ { "id": "A0ABI0P6M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil domain-containing protein 101", "type": "synonym", "evidence": [ { "id": "A0ABI0P6M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9/entry#names_and_taxonomy" } ] }, { "name": "SAGA complex-associated factor 29", "type": "synonym", "evidence": [ { "id": "A0ABI0P6M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9/entry#names_and_taxonomy" } ] }, { "name": "SAGA-associated factor 29 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059737223", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059737223" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P6M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SGF29", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9", "locus": { "chromosome": "25", "start_pos": 26123452, "end_pos": 26082046, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016883", "url": "https://www.ensembl.org/id/ENSBTAG00000016883" } ] } } ], "crossref": [ { "id": "cd20393", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20393", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20394", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20394", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "510859", "url": "https://www.ncbi.nlm.nih.gov/gene/510859", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010750", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010750", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037802", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037802", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047288", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047288", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21539", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21539", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21539:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21539:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059737223", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059737223", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TIV5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIV5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNL9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNL9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6M9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDCCPPGASGHGILQAFAWSGLPFLPPGDLPDPGIKPHLVCLLHWQAPLYTMALVSADSRIAELLTELHQLIKQTQEERSRSEHNLVNIQKTHERMQTENKISPYYRTKLRGLYTTAKADAEAECNILRKALDKIAEIKSLLEERRIAAKIAGLYNDSEPPRKTMRRGVLMTLLQQSAMTLPLWIGKPGDKPPPLCGAIPASGDYVAKPGDKVAARVKAVDGDEQWILAEVVSYSHATNKYEVDDIDEEGKERHTLSRRRIIPLPQWKANPETDPEALFQKEQLVLALYPQTTCFYRALIHTPPQRPQDDYSVLFEDTSYADGYSPPLNVAQRYVVACKEPKKK", "length": 344, "header": "tr|A0ABI0P6M9-1|A0ABI0P6M9_BOVIN Isoform 1 of SAGA-associated factor 29 OS=Bos taurus OX=9913 GN=SGF29 PE=4 SV=1 CANONICAL=A0ABI0P6M9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TIV5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9/entry#A0AAA9TIV5-1", "sequence": { "sequence": "MAPLYTMALVSADSRIAELLTELHQLIKQTQEERSRSEHNLVNIQKTHERMQTENKISPYYRTKLRGLYTTAKADAEAECNILRKALDKIAEIKSLLEERRIAAKIAGLYNDSEPPRKTMRRGVLMTLLQQSAMTLPLWIGKPGDKPPPLCGAIPASGDYVAKPGDKVAARVKAVDGDEQWILAEVVSYSHATNKYEVDDIDEEGKERHTLSRRRIIPLPQWKANPETDPEALFQKEQLVLALYPQTTCFYRALIHTPPQRPQDDYSVLFEDTSYADGYSPPLNVAQRYVVACKEPKKK", "length": 299, "header": "tr|A0AAA9TIV5-1|A0ABI0P6M9_BOVIN Computationally mapped isoform of SAGA-associated factor 29 OS=Bos taurus OX=9913 GN=SGF29 PE=4 SV=1 CANONICAL=A0ABI0P6M9-1" }, "locus": { "chromosome": "25", "start_pos": 26123363, "end_pos": 26093714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100175.2", "url": "https://www.ensembl.org/id/ENSBTAT00000100175.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098388.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098388.1" } ] } }, { "isoform_ac": "A0AAA9TNL9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9/entry#A0AAA9TNL9-1", "sequence": { "sequence": "MPTRAVAVGVDGGFSLAATFPASHSWEMRRESMAPLYTMALVSADSRIAELLTELHQLIKQTQEERSRSEHNLVNIQKTHERMQTENKISPYYRTKLRGLYTTAKADAEAECNILRKALDKIAEIKSLLEERRIAAKIAGLYNDSEPPRKTMRRGVLMTLLQQSAMTLPLWIGKPGDKPPPLCGAIPASGDYVAKPGDKVAARVKAVDGDEQWILAEVVSYSHATNKYEVDDIDEEGKERHTLSRRRIIPLPQWKANPETDPEALFQKEQLVLALYPQTTCFYRALIHTPPQRPQDDYSVLFEDTSYADGYSPPLNVAQRYVVACKEPKKK", "length": 331, "header": "tr|A0AAA9TNL9-1|A0ABI0P6M9_BOVIN Computationally mapped isoform of SAGA-associated factor 29 OS=Bos taurus OX=9913 GN=SGF29 PE=4 SV=1 CANONICAL=A0ABI0P6M9-1" }, "locus": { "chromosome": "25", "start_pos": 26123363, "end_pos": 26082754, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112309.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112309.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100132.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100132.1" } ] } }, { "isoform_ac": "A0ABI0P6M9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9/entry#A0ABI0P6M9-1", "sequence": { "sequence": "MDCCPPGASGHGILQAFAWSGLPFLPPGDLPDPGIKPHLVCLLHWQAPLYTMALVSADSRIAELLTELHQLIKQTQEERSRSEHNLVNIQKTHERMQTENKISPYYRTKLRGLYTTAKADAEAECNILRKALDKIAEIKSLLEERRIAAKIAGLYNDSEPPRKTMRRGVLMTLLQQSAMTLPLWIGKPGDKPPPLCGAIPASGDYVAKPGDKVAARVKAVDGDEQWILAEVVSYSHATNKYEVDDIDEEGKERHTLSRRRIIPLPQWKANPETDPEALFQKEQLVLALYPQTTCFYRALIHTPPQRPQDDYSVLFEDTSYADGYSPPLNVAQRYVVACKEPKKK", "length": 344, "header": "tr|A0ABI0P6M9-1|A0ABI0P6M9_BOVIN Isoform 1 of SAGA-associated factor 29 OS=Bos taurus OX=9913 GN=SGF29 PE=4 SV=1 CANONICAL=A0ABI0P6M9-1" }, "locus": { "chromosome": "25", "start_pos": 26123363, "end_pos": 26096323, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154135.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154135.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107057.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107057.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P6M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P6M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9" } ], "pmid": "" }, { "name": "ATAC complex", "id": "GO:0140672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140672", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P6M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P6M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9" } ], "pmid": "" }, { "name": "regulation of cell division", "id": "GO:0051302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051302", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P6M9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ABI0P6M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6M9" }, { "id": "PS51518", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51518" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SGF29 C-terminal", "eco_id": "ECO_0000259", "start_pos": 203, "end_pos": 344, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0ABI0P6Q9-1", "uniprot_ac": "A0ABI0P6Q9", "uniprot_id": "A0ABI0P6Q9_BOVIN", "mass": { "chemical_mass": 49450.0, "monoisotopic_mass": 49450.0 }, "refseq": {}, "gene_names": [ { "name": "IVL", "type": "recommended", "evidence": [ { "id": "A0ABI0P6Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q9" } ] } ], "protein_names": [ { "name": "Involucrin", "type": "synonym", "evidence": [ { "id": "A0ABI0P6Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P6Q9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IVL", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q9", "locus": { "chromosome": "3", "start_pos": 17839282, "end_pos": 17842949, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017827", "url": "https://www.ensembl.org/id/ENSBTAG00000017827" } ] } } ], "crossref": [ { "id": "IPR009733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF06994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10583", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10583", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TN50", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TN50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TN50-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TN50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P483", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P483", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P483-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P483-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6Q9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQQHTLPVIQPPALSQESLKPASPPTNTQQEQVKQPTPLPAPCQKVHSELPGEVPLELGEKHTIVKGVAEQKCEPQQPEPEQQEQHVEQQQQESQVQEQYVEEQQQESQVQEVHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQEESQVQEQYVEQQQQESKVQEQHVKQQQQESQVPEEHVKQQQQESQVPEVHVEQQQQESQVPEKHVELQQQESQVPEVHVELQQQESQVPKVHVKKQHQELQEQQVQQQKEQHVEHQEAEHLGLQLEQEKTQREQQLKGQLEQEKKVLGQHLDQEPAKREEQMEKKEEQLLEQQEGQLKQPVFVPAPGQVQETHPVLPLKEKALPSEEAGGVVPSKHK", "length": 422, "header": "tr|A0ABI0P6Q9-1|A0ABI0P6Q9_BOVIN Isoform 1 of Involucrin OS=Bos taurus OX=9913 GN=IVL PE=1 SV=1 CANONICAL=A0ABI0P6Q9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TN50-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q9/entry#A0AAA9TN50-1", "sequence": { "sequence": "MSQQHTLPVIQPPALSQESLKPASPPTNTQQEQVKQPTPLPAPCQKVHSELPGEVPLELGEKHTIVKGVAEQKCEPQQPEPEQQEQHVEQQQQESQVQEQYVEEQQQESQVQEVHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQEESQVQEQYVEQQQQESKVQEQHVKQQQQESQVPEEHVKQQQQESQVPEVHVEQQQQESQVPKVHVKKQHQELQEQQVQQQKEQHVEHQEAEHLGLQLEQEKTQREQQLKGQLEQEKKVLGQHLDQEPAKREEQMEKKEEQLLEQQEGQLKQPVFVPAPGQVQETHPVLPLKEKALPSEEAGGVVPSKHK", "length": 394, "header": "tr|A0AAA9TN50-1|A0ABI0P6Q9_BOVIN Computationally mapped isoform of Involucrin OS=Bos taurus OX=9913 GN=IVL PE=1 SV=2 CANONICAL=A0ABI0P6Q9-1" }, "locus": { "chromosome": "3", "start_pos": 17841593, "end_pos": 17840286, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023700.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023700.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097775.2", "url": "https://www.ensembl.org/id/ENSBTAP00000097775.2" } ] } }, { "isoform_ac": "A0ABI0P483-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q9/entry#A0ABI0P483-1", "sequence": { "sequence": "MSQQHTLPVIQPPALSQESLKPASPPTNTQQEQVKQPTPLPAPCQKVHSELPGEVPLELGEKHTIVKGVAEQKCEPQQPEPEQQEQHVEQQQQESQVQEQYVEEQQQESQVQEVHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQEESQVQEQYVEQQQQESKVQEQHVKQQQQESQVPEEHVKQQQQESQVPEKHVELQQQESQVPEVHVELQQQESQVPKVHVKKQHQELQEQQVQQQKEQHVEHQEAEHLGLQLEQEKTQREQQLKGQLEQEKKVLGQHLDQEPAKREEQMEKKEEQLLEQQEGQLKQPVFVPAPGQVQETHPVLPLKEKALPSEEAGGVVPSKHK", "length": 366, "header": "tr|A0ABI0P483-1|A0ABI0P6Q9_BOVIN Computationally mapped isoform of Involucrin OS=Bos taurus OX=9913 GN=IVL PE=1 SV=1 CANONICAL=A0ABI0P6Q9-1" }, "locus": { "chromosome": "3", "start_pos": 17841593, "end_pos": 17840286, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141080.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141080.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106347.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106347.1" } ] } }, { "isoform_ac": "A0ABI0P6Q9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q9/entry#A0ABI0P6Q9-1", "sequence": { "sequence": "MSQQHTLPVIQPPALSQESLKPASPPTNTQQEQVKQPTPLPAPCQKVHSELPGEVPLELGEKHTIVKGVAEQKCEPQQPEPEQQEQHVEQQQQESQVQEQYVEEQQQESQVQEVHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQQESQVQEQHVEQQQEESQVQEQYVEQQQQESKVQEQHVKQQQQESQVPEEHVKQQQQESQVPEVHVEQQQQESQVPEKHVELQQQESQVPEVHVELQQQESQVPKVHVKKQHQELQEQQVQQQKEQHVEHQEAEHLGLQLEQEKTQREQQLKGQLEQEKKVLGQHLDQEPAKREEQMEKKEEQLLEQQEGQLKQPVFVPAPGQVQETHPVLPLKEKALPSEEAGGVVPSKHK", "length": 422, "header": "tr|A0ABI0P6Q9-1|A0ABI0P6Q9_BOVIN Isoform 1 of Involucrin OS=Bos taurus OX=9913 GN=IVL PE=1 SV=1 CANONICAL=A0ABI0P6Q9-1" }, "locus": { "chromosome": "3", "start_pos": 17841593, "end_pos": 17840286, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137510.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137510.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107687.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107687.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "keratinocyte differentiation", "id": "GO:0030216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030216", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P6Q9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cornified envelope", "id": "GO:0001533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001533", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P6Q9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6Q9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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[], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F6RC82-1", "uniprot_ac": "F6RC82", "uniprot_id": "F6RC82_BOVIN", "mass": { "chemical_mass": 35726.0, "monoisotopic_mass": 35726.0 }, "refseq": { "ac": "XP_059731172", "name": "dnaJ homolog subfamily B member 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059731172" }, "gene_names": [ { "name": "DNAJB2", "type": "recommended", "evidence": [ { "id": "F6RC82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RC82" } ] }, { "name": "DNAJB2", "type": "synonym", "evidence": [ { "id": "XP_059731172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059731172" } ] } ], "protein_names": [ { "name": "DnaJ heat shock protein family (Hsp40) member B2", "type": "synonym", "evidence": [ { "id": "F6RC82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RC82/entry#names_and_taxonomy" } ] }, { "name": "dnaJ homolog subfamily B member 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059731172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059731172" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RC82", "url": "https://www.uniprot.org/uniprotkb/F6RC82" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DNAJB2", "url": "https://www.uniprot.org/uniprotkb/F6RC82", "locus": { "chromosome": "2", "start_pos": 107235623, "end_pos": 107227669, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013782", "url": "https://www.ensembl.org/id/ENSBTAG00000013782" } ] } } ], "crossref": [ { "id": "ENSBTAG00000013782", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013782", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "533668", "url": "https://www.ncbi.nlm.nih.gov/gene/533668", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018253", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059731172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059731172", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TVG8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVG8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RC82", "url": "https://www.uniprot.org/uniprotkb/F6RC82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RC82-1", "url": "https://www.uniprot.org/uniprotkb/F6RC82-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASYYEILDVPRSASADDIKKAYRKKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDLYGREGLTGAGTGPSRAEAGSGGPGFTFTFRSPEEVFREFFGSGDPFAELFDDLGPFSELQNRGSRHSGPFFTFSSSFPGHSDFSSSSFSFSPGAGAFRSVSTSTTFVQGRRITTRRIMENGQERVEVEEDGQLKSVTINGIPDDLALGLELSRREQQQSVTSRSGATQVRQTPVSRPLDGSLSEEDEDLQLAMAYSLSEMEAAGKKPAGGRGAQRRRQGQPKAQNHDPGVREPHEGARGDTAKPSPSPEEKATRCLIL", "length": 325, "header": "tr|F6RC82-1|F6RC82_BOVIN Isoform 1 of DnaJ heat shock protein family (Hsp40) member B2 OS=Bos taurus OX=9913 GN=DNAJB2 PE=4 SV=1 CANONICAL=F6RC82-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TVG8-1", "url": "https://www.uniprot.org/uniprotkb/F6RC82/entry#A0AAA9TVG8-1", "sequence": { "sequence": "MASYYEILDVPRSASADDIKKAYRKKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDLYGREGLTGAGTGPSRAEAGSGGPGFTFTFRSPEEVFREFFGSGDPFAELFDDLGPFSELQNRGSRHSGPFFTFSSSFPGHSDFSSSSFSFSPGAGAFRSVSTSTTFVQGRRITTRRIMENGQERVEVEEDGQLKSVTINGIPDDLALGLELSRREQQQSVTSRSGATQVRQTPVSRPLDGSLSEEDEDLQLAMAYSLSEMEAAGKKPAGIQRSQAFPADSRSPLFD", "length": 293, "header": "tr|A0AAA9TVG8-1|F6RC82_BOVIN Computationally mapped isoform of DnaJ heat shock protein family (Hsp40) member B2 OS=Bos taurus OX=9913 GN=DNAJB2 PE=4 SV=1 CANONICAL=F6RC82-1" }, "locus": { "chromosome": "2", "start_pos": 107235086, "end_pos": 107228046, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123084.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123084.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102358.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102358.1" } ] } }, { "isoform_ac": "F6RC82-1", "url": "https://www.uniprot.org/uniprotkb/F6RC82/entry#F6RC82-1", "sequence": { "sequence": "MASYYEILDVPRSASADDIKKAYRKKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDLYGREGLTGAGTGPSRAEAGSGGPGFTFTFRSPEEVFREFFGSGDPFAELFDDLGPFSELQNRGSRHSGPFFTFSSSFPGHSDFSSSSFSFSPGAGAFRSVSTSTTFVQGRRITTRRIMENGQERVEVEEDGQLKSVTINGIPDDLALGLELSRREQQQSVTSRSGATQVRQTPVSRPLDGSLSEEDEDLQLAMAYSLSEMEAAGKKPAGGRGAQRRRQGQPKAQNHDPGVREPHEGARGDTAKPSPSPEEKATRCLIL", "length": 325, "header": "tr|F6RC82-1|F6RC82_BOVIN Isoform 1 of DnaJ heat shock protein family (Hsp40) member B2 OS=Bos taurus OX=9913 GN=DNAJB2 PE=4 SV=1 CANONICAL=F6RC82-1" }, "locus": { "chromosome": "2", "start_pos": 107233052, "end_pos": 107228046, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018327.7", "url": "https://www.ensembl.org/id/ENSBTAT00000018327.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018327.5", "url": "https://www.ensembl.org/id/ENSBTAP00000018327.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:533668", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:533668", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6RC82", "url": "https://www.uniprot.org/uniprotkb/F6RC82" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "F6RC82", "url": "https://www.uniprot.org/uniprotkb/F6RC82" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "F6RC82", "url": "https://www.uniprot.org/uniprotkb/F6RC82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RC82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RC82" }, { "id": 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"" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of axonogenesis", "id": "GO:0050772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050772", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P781", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P781" } ], "pmid": "" }, { "name": "glial cell differentiation", "id": "GO:0010001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010001", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P781", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P781" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], 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Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.", "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5V4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5V4#function" }, { "database": "UniProtKB", "id": "ARBA00058368", "url": "https://www.uniprot.org/uniprotkb/ARBA00058368#function" }, { "database": "UniProtKB", "id": "F6QEW8", "url": "https://www.uniprot.org/uniprotkb/F6QEW8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0ABI0P5V4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5V4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "JTB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5V4", "locus": { "chromosome": "3", "start_pos": 16464004, "end_pos": 16461648, "strand": "-", "evidence": [ 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