[ { "uniprot_canonical_ac": "F1MPL1-1", "uniprot_id": "F1MPL1_BOVIN", "mass": 84431.0, "length": 742, "protein_name": "Mitofusin 1", "gene_name": "MFN1", "organism": "Bovine", "refseq_name": "mitofusin-1", "refseq_ac": "NP_001193437", "gene_names_uniprotkb": "MFN1", "gene_names_refseq": "MFN1; MFN2", "protein_names_uniprotkb": "Mitofusin 1", "protein_names_refseq": "mitofusin 2; mitofusin-1", "tax_id": 9913, "disease": "", "pathway": " (bta:515180); (R-BTA-5205685); (R-BTA-9013419); (R-BTA-983231)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "22245982;34864096", "class_list": "", "function": "The relationship between MFN1 copy number variation and growth traits of beef cattle., [RefSeq, PubMed]; The results showed that high level of Mfn1 expression significantly improved the embryo development rates by increasing ATP level and Deltapsim, while reducing H(2)O(2) generation., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0098799 outer mitochondrial membrane protein complex", "go_biological_process": "GO:0008053 mitochondrial fusion;GO:0010918 positive regulation of mitochondrial membrane potential;GO:0046039 GTP metabolic process;GO:0051646 mitochondrion localization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1MPL1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MK72-1", "uniprot_id": "F1MK72_BOVIN", "mass": 27786.0, "length": 244, "protein_name": "Coenzyme Q-binding protein COQ10 homolog B, mitochondrial", "gene_name": "COQ10B", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "COQ10B", "gene_names_refseq": "", "protein_names_uniprotkb": "Coenzyme Q-binding protein COQ10 homolog B, mitochondrial", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-611105); (R-BTA-9864848)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0048039 ubiquinone binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005739 mitochondrion", "go_biological_process": "GO:0045333 cellular respiration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MK72-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MM71-1", "uniprot_id": "F1MM71_BOVIN", "mass": 55291.0, "length": 482, "protein_name": "Interferon induced protein with tetratricopeptide repeats 1", "gene_name": "LOC100139670", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC100139670", "gene_names_refseq": "", "protein_names_uniprotkb": "Interferon induced protein with tetratricopeptide repeats 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1169408)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0004857 enzyme inhibitor activity;GO:0140610 RNA sequestering activity", "go_cellular_component": "GO:0005829 cytosol;GO:0043657 host cell", "go_biological_process": "GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0051707 response to other organism;GO:0071360 cellular response to exogenous dsRNA;GO:0071357 cellular response to type I interferon", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MM71-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLV5-1", "uniprot_id": "F1MLV5_BOVIN", "mass": 56773.0, "length": 495, "protein_name": "Cytochrome P450 family 2 subfamily C member 23", "gene_name": "CYP2C23", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CYP2C23", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome P450 family 2 subfamily C member 23", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005737 cytoplasm", "go_biological_process": "GO:0042178 xenobiotic catabolic process;GO:0019373 epoxygenase P450 pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLV5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MS86-1", "uniprot_id": "F1MS86_BOVIN", "mass": 34315.0, "length": 313, "protein_name": "Derlin", "gene_name": "DERL3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DERL3", "gene_names_refseq": "", "protein_names_uniprotkb": "Derlin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-382556); (R-BTA-9931269)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005047 signal recognition particle binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0010498 proteasomal protein catabolic process;GO:0033554 cellular response to stress;GO:0006487 protein N-linked glycosylation;GO:0030968 endoplasmic reticulum unfolded protein response;GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MS86-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MQF9-1", "uniprot_id": "F1MQF9_BOVIN", "mass": 132601.0, "length": 1145, "protein_name": "Solute carrier family 9 member C1", "gene_name": "SLC9C1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC9C1", "gene_names_refseq": "", "protein_names_uniprotkb": "Solute carrier family 9 member C1; Na(+)/H(+) exchanger 10; Sodium/hydrogen exchanger 10; Sperm-specific Na(+)/H(+) exchanger", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Sperm-specific solute carrier involved in intracellular pH regulation of spermatozoa. Required for sperm motility and fertility. Involved in sperm cell hyperactivation, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for the expression and bicarbonate regulation of the soluble adenylyl cyclase (sAC)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015385 sodium:proton antiporter activity;GO:0005216 monoatomic ion channel activity;GO:0015386 potassium:proton antiporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane;GO:0031514 motile cilium", "go_biological_process": "GO:0051453 regulation of intracellular pH;GO:0071805 potassium ion transmembrane transport;GO:0098719 sodium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MQF9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MQ89-1", "uniprot_id": "F1MQ89_BOVIN", "mass": 83424.0, "length": 739, "protein_name": "Conserved oligomeric Golgi complex subunit 2", "gene_name": "COG2", "organism": "Bovine", "refseq_name": "conserved oligomeric Golgi complex subunit 2", "refseq_ac": "NP_001070307", "gene_names_uniprotkb": "COG2", "gene_names_refseq": "COG2", "protein_names_uniprotkb": "Conserved oligomeric Golgi complex subunit 2; Component of oligomeric Golgi complex 2", "protein_names_refseq": "conserved oligomeric Golgi complex subunit 2", "tax_id": 9913, "disease": "", "pathway": " (bta:512213); (R-BTA-6807878); (R-BTA-6811438); (R-BTA-6811440)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005795 Golgi stack;GO:0017119 Golgi transport complex", "go_biological_process": "GO:0015031 protein transport;GO:0007030 Golgi organization;GO:0000301 retrograde transport, vesicle recycling within Golgi;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MQ89-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLK9-1", "uniprot_id": "F1MLK9_BOVIN", "mass": 27026.0, "length": 235, "protein_name": "Iron-sulfur cluster co-chaperone protein HscB", "gene_name": "HSCB", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HSCB", "gene_names_refseq": "", "protein_names_uniprotkb": "Iron-sulfur cluster co-chaperone protein HscB", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1268020); (R-BTA-1362409); (R-BTA-6799198); (R-BTA-9865881)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a co-chaperone in iron-sulfur cluster assembly in mitochondria. Required for incorporation of iron-sulfur clusters into SDHB, the iron-sulfur protein subunit of succinate dehydrogenase that is involved in complex II of the mitochondrial electron transport chain. Recruited to SDHB by interaction with SDHAF1 which first binds SDHB and then recruits the iron-sulfur transfer complex formed by HSC20, HSPA9 and ISCU through direct binding to HSC20. Plays an essential role in hematopoiesis., [UniProtKB, UniProtKB]; Acts as a co-chaperone in iron-sulfur cluster assembly in the cytoplasm. Also mediates complex formation between components of the cytosolic iron-sulfur biogenesis pathway and the CIA targeting complex composed of CIAO1, DIPK1B/FAM69B and MMS19 by binding directly to the scaffold protein ISCU and to CIAO1. This facilitates iron-sulfur cluster insertion into a number of cytoplasmic and nuclear proteins including POLD1, ELP3, DPYD and PPAT., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051087 protein-folding chaperone binding;GO:0001671 ATPase activator activity;GO:0042802 identical protein binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0044571 [2Fe-2S] cluster assembly;GO:0051259 protein complex oligomerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLK9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MJQ6-1", "uniprot_id": "F1MJQ6_BOVIN", "mass": 172175.0, "length": 1746, "protein_name": "Collagen type V alpha 3 chain", "gene_name": "COL5A3", "organism": "Bovine", "refseq_name": "collagen alpha-3(V) chain isoform X3", "refseq_ac": "XP_005208792", "gene_names_uniprotkb": "COL5A3", "gene_names_refseq": "COL5A3", "protein_names_uniprotkb": "Collagen type V alpha 3 chain", "protein_names_refseq": "collagen alpha-3(V) chain isoform X3", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1442490); (R-BTA-1566977); (R-BTA-1650814); (R-BTA-186797); (R-BTA-2022090); (R-BTA-216083); (R-BTA-3000171); (R-BTA-3000178); (R-BTA-8874081); (R-BTA-8948216)", "pathway_count": 10, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005201 extracellular matrix structural constituent;GO:0008201 heparin binding;GO:0030020 extracellular matrix structural constituent conferring tensile strength", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix;GO:0005588 collagen type V trimer", 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"uniprot_canonical_ac": "F1MJQ8-1", "uniprot_id": "F1MJQ8_BOVIN", "mass": 59145.0, "length": 521, "protein_name": "RNA-binding region-containing protein 3", "gene_name": "RNPC3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RNPC3", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA-binding region-containing protein 3; RNA-binding motif protein 40", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005689 U12-type spliceosomal complex", "go_biological_process": "GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MJQ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MJS2-1", "uniprot_id": "F1MJS2_BOVIN", "mass": 62798.0, "length": 590, "protein_name": "Transcription factor 7 like 1", "gene_name": "TCF7L1", "organism": "Bovine", "refseq_name": "transcription factor 7-like 1 isoform X2", "refseq_ac": "XP_024855196", "gene_names_uniprotkb": "TCF7L1", "gene_names_refseq": "TCF7L1", "protein_names_uniprotkb": "Transcription factor 7 like 1", "protein_names_refseq": "transcription factor 7-like 1 isoform X2", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-201722); (R-BTA-3769402); (R-BTA-4641265); (R-BTA-8951430); (R-BTA-9825892)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:1990907 beta-catenin-TCF complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0060070 canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MJS2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MJS7-1", "uniprot_id": "F1MJS7_BOVIN", "mass": 88264.0, "length": 790, "protein_name": "GATOR2 complex protein WDR24", "gene_name": "WDR24", "organism": "Bovine", "refseq_name": "GATOR2 complex protein WDR24 isoform X1", "refseq_ac": "XP_005224463", "gene_names_uniprotkb": "WDR24", "gene_names_refseq": "WDR24", "protein_names_uniprotkb": "GATOR2 complex protein WDR24; 2.3.2.27; WD repeat-containing protein 24", "protein_names_refseq": "GATOR2 complex protein WDR24 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-9639288)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalytic component of the GATOR2 complex, a multiprotein complex that acts as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. In addition to its role in regulation of the mTORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux. Within the GATOR2 complex, WDR24 constitutes the catalytic subunit that mediates 'Lys-6'-linked ubiquitination of NPRL2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8J8YNK6;M5FJX7", "ec_number_list": "2.7.11.1;2.1.1.-;2.3.2.27;7.1.2.2;3.6.5.-;1.11.1.-", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005765 lysosomal membrane;GO:0005774 vacuolar membrane;GO:0061700 GATOR2 complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0006914 autophagy;GO:0016239 positive regulation of macroautophagy;GO:0034198 cellular response to amino acid starvation;GO:0085020 protein K6-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MJS7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MJT5-1", "uniprot_id": "F1MJT5_BOVIN", "mass": 61289.0, "length": 545, "protein_name": "Zinc finger protein 280B", "gene_name": "ZNF280B", "organism": "Bovine", "refseq_name": "zinc finger protein 280B", "refseq_ac": "NP_001071403", "gene_names_uniprotkb": "ZNF280B", "gene_names_refseq": "SUHW2; ZNF280B", "protein_names_uniprotkb": "Zinc finger protein 280B", "protein_names_refseq": "suppressor of hairy wing homolog 2; zinc finger protein 280B", "tax_id": 9913, "disease": "", "pathway": " (bta:517697)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May function as a transcription factor., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MJT5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MJU1-1", "uniprot_id": "F1MJU1_BOVIN", "mass": 18281.0, "length": 161, "protein_name": "Histone H2B", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Histone H2B", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-110330); (R-BTA-110331); (R-BTA-171306); (R-BTA-201722); (R-BTA-212300); (R-BTA-2299718); (R-BTA-2559580); (R-BTA-2559582); (R-BTA-2559586); (R-BTA-3214815); (R-BTA-3214847); (R-BTA-427359); (R-BTA-427413); (R-BTA-5250924); (R-BTA-5578749); (R-BTA-5625886); (R-BTA-5689880); (R-BTA-5693565); (R-BTA-5693571); (R-BTA-5693607); (R-BTA-606279); (R-BTA-68616); (R-BTA-69473); (R-BTA-73728); (R-BTA-73772); (R-BTA-8866654); (R-BTA-8936459); (R-BTA-9018519); (R-BTA-9670095); (R-BTA-9764725); (R-BTA-9841922); (R-BTA-9843940); (R-BTA-9843970); (R-BTA-9909649); (R-BTA-9940951); (R-BTA-9943411); (R-BTA-9943962); (R-BTA-9970672)", "pathway_count": 38, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0006325 chromatin organization;GO:0002227 innate immune response in mucosa", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MJU1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MJU5-1", "uniprot_id": "F1MJU5_BOVIN", "mass": 36227.0, "length": 318, "protein_name": "Ig-like domain-containing protein", "gene_name": "BOLA-DRB3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "BOLA-DRB3", "gene_names_refseq": "", "protein_names_uniprotkb": "Ig-like domain-containing protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-202424); (R-BTA-202427); (R-BTA-202430); (R-BTA-202433); (R-BTA-2132295); (R-BTA-389948)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0023026 MHC class II protein complex binding;GO:0042605 peptide antigen binding", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0042613 MHC class II protein complex", "go_biological_process": "GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002503 peptide antigen assembly with MHC class II protein complex;GO:0002250 adaptive immune response;GO:0050870 positive regulation of T cell activation;GO:0050778 positive regulation of immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MJU5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MJW4-1", "uniprot_id": "F1MJW4_BOVIN", "mass": 59738.0, "length": 526, "protein_name": "FAM20A golgi associated secretory pathway pseudokinase", "gene_name": "FAM20A", "organism": "Bovine", "refseq_name": "pseudokinase FAM20A isoform X1", "refseq_ac": "XP_002707814", "gene_names_uniprotkb": "FAM20A", "gene_names_refseq": "FAM20A", "protein_names_uniprotkb": "FAM20A golgi associated secretory pathway pseudokinase", "protein_names_refseq": "pseudokinase FAM20A isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:521099); (R-BTA-381426); (R-BTA-8957275)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0043539 protein serine/threonine kinase activator activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0070166 enamel mineralization;GO:0055074 calcium ion homeostasis;GO:0044691 tooth eruption", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MJW4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MJX8-1", "uniprot_id": "F1MJX8_BOVIN", "mass": 62792.0, "length": 542, "protein_name": "DnaJ homolog subfamily C member 1", "gene_name": "DNAJC1", "organism": "Bovine", "refseq_name": "dnaJ homolog subfamily C member 1", "refseq_ac": "XP_024856724", "gene_names_uniprotkb": "DNAJC1", "gene_names_refseq": "DNAJC1", "protein_names_uniprotkb": "DnaJ homolog subfamily C member 1; DnaJ protein homolog MTJ1", "protein_names_refseq": "dnaJ homolog subfamily C member 1", "tax_id": 9913, "disease": "", "pathway": " (bta:781036)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May modulate protein synthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, 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Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0001525 angiogenesis;GO:0007155 cell adhesion;GO:0030154 cell differentiation;GO:0045766 positive regulation of angiogenesis;GO:0001938 positive regulation of endothelial cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MKY1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MKY3-1", "uniprot_id": "F1MKY3_BOVIN", "mass": 66683.0, "length": 624, "protein_name": "Sushi domain containing 5", "gene_name": "SUSD5", "organism": "Bovine", "refseq_name": "sushi domain-containing protein 5", "refseq_ac": "XP_024838967", "gene_names_uniprotkb": "SUSD5", "gene_names_refseq": "SUSD5", "protein_names_uniprotkb": "Sushi domain containing 5", "protein_names_refseq": "sushi domain-containing protein 5", "tax_id": 9913, "disease": "", "pathway": " (bta:524663)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005540 hyaluronic acid binding", "go_cellular_component": "", "go_biological_process": "GO:0007155 cell adhesion;GO:0007219 Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MKY3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MKY9-1", "uniprot_id": "F1MKY9_BOVIN", "mass": 228525.0, "length": 2127, "protein_name": "Alpha-protein kinase 2", "gene_name": "ALPK2", "organism": "Bovine", "refseq_name": "alpha-protein kinase 2", "refseq_ac": "NP_001179177", "gene_names_uniprotkb": "ALPK2", "gene_names_refseq": "ALPK2", "protein_names_uniprotkb": "Alpha-protein kinase 2; 2.7.11.1; Heart alpha-protein kinase", "protein_names_refseq": "alpha-protein kinase 2", "tax_id": 9913, "disease": "", "pathway": " (bta:510218)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation. Regulates cardiac development and cardiomyocyte differentiation by negatively regulating Wnt/beta-catenin signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0003007 heart morphogenesis;GO:0042981 regulation of apoptotic process;GO:0055013 cardiac muscle cell development;GO:0030010 establishment of cell polarity;GO:0003308 negative regulation of Wnt signaling pathway involved in heart development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MKY9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MKZ5-1", "uniprot_id": "F1MKZ5_BOVIN", "mass": 30270.0, "length": 264, "protein_name": "40S ribosomal protein S6", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "40S ribosomal protein S6", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MKZ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MKZ6-1", "uniprot_id": "F1MKZ6_BOVIN", "mass": 515037.0, "length": 4596, "protein_name": "Low-density lipoprotein receptor-related protein 1B", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Low-density lipoprotein receptor-related protein 1B; Low-density lipoprotein receptor-related protein-deleted in tumor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0016020 membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0006898 receptor-mediated endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MKZ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1ML13-1", "uniprot_id": "F1ML13_BOVIN", "mass": 120361.0, "length": 1073, "protein_name": "Semaphorin-5A", "gene_name": "SEMA5A", "organism": "Bovine", "refseq_name": "semaphorin-5A", "refseq_ac": "XP_002696487", "gene_names_uniprotkb": "SEMA5A", "gene_names_refseq": "SEMA5A", "protein_names_uniprotkb": "Semaphorin-5A; Semaphorin-F", "protein_names_refseq": "semaphorin-5A", "tax_id": 9913, "disease": "", "pathway": " (bta:506636); (R-BTA-416700); (R-BTA-5173214)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0071526 semaphorin-plexin signaling pathway;GO:0001755 neural crest cell migration;GO:0007411 axon guidance;GO:0048675 axon extension", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1ML13-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1ML32-1", "uniprot_id": "F1ML32_BOVIN", "mass": 97982.0, "length": 932, "protein_name": "Scavenger receptor class F member 1", "gene_name": "SCARF1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SCARF1", "gene_names_refseq": "", "protein_names_uniprotkb": "Scavenger receptor class F member 1; Acetyl LDL receptor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:616566)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005044 scavenger receptor activity;GO:0030169 low-density lipoprotein particle binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0048680 positive regulation of axon regeneration;GO:0010976 positive regulation of neuron projection development;GO:0016322 neuron remodeling;GO:0016358 dendrite development;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1ML32-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1ML34-1", "uniprot_id": "F1ML34_BOVIN", "mass": 44069.0, "length": 380, "protein_name": "PX domain-containing protein", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "PX domain-containing protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035091 phosphatidylinositol binding;GO:0034452 dynactin binding", "go_cellular_component": "GO:0005768 endosome;GO:0005829 cytosol", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0042147 retrograde transport, endosome to Golgi;GO:0006907 pinocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1ML34-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1ML72-1", "uniprot_id": "F1ML72_BOVIN", "mass": 13293.0, "length": 117, "protein_name": "Large ribosomal subunit protein eL34", "gene_name": "RPL34", "organism": "Bovine", "refseq_name": "large ribosomal subunit protein eL34", "refseq_ac": "NP_001193150", "gene_names_uniprotkb": "RPL34", "gene_names_refseq": "RPL34", "protein_names_uniprotkb": "Large ribosomal subunit protein eL34; 60S ribosomal protein L34", "protein_names_refseq": "large ribosomal subunit protein eL34", "tax_id": 9913, "disease": "", "pathway": " (bta:505603); (R-BTA-156827); (R-BTA-1799339); (R-BTA-6791226); (R-BTA-72689); (R-BTA-72706); (R-BTA-975956); (R-BTA-975957); (R-BTA-9954709); (R-BTA-9954714); (R-BTA-9954716)", "pathway_count": 11, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0045202 synapse;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1ML72-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1ML73-1", "uniprot_id": "F1ML73_BOVIN", "mass": 21697.0, "length": 185, "protein_name": "DNA dC->dU-editing enzyme APOBEC-3G", "gene_name": "APOBEC3Z1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "APOBEC3Z1", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA dC->dU-editing enzyme APOBEC-3G; 3.5.4.38; Deoxycytidine deaminase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.4.38", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000932 P-body", "go_biological_process": "GO:0045087 innate immune response;GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1ML73-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1ML88-1", "uniprot_id": "F1ML88_BOVIN", "mass": 80326.0, "length": 711, "protein_name": "Pseudouridylate synthase 7 homolog", "gene_name": "PUS7", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PUS7", "gene_names_refseq": "", "protein_names_uniprotkb": "Pseudouridylate synthase 7 homolog", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Pseudouridylate synthase that catalyzes pseudouridylation of RNAs. Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylation of RNA fragments derived from tRNAs (tRFs): pseudouridylated tRFs inhibit translation by targeting the translation initiation complex. Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3'. Acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions. Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing. In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudouridylation of many RNA types., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.4.99.25;5.4.99.12;5.4.99.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0019899 enzyme binding;GO:0009982 pseudouridine synthase activity;GO:0160150 tRNA pseudouridine(13) synthase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0031119 tRNA pseudouridine synthesis;GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:1902036 regulation of hematopoietic stem cell differentiation;GO:0017148 negative regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1ML88-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1ML91-1", "uniprot_id": "F1ML91_BOVIN", "mass": 53789.0, "length": 495, "protein_name": "Cytokine receptor-like factor 1", "gene_name": "CRLF1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CRLF1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytokine receptor-like factor 1; Cytokine-like factor 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0019955 cytokine binding;GO:0005127 ciliary neurotrophic factor receptor binding;GO:0140597 protein carrier chaperone", "go_cellular_component": "GO:0005615 extracellular space;GO:0097058 CRLF-CLCF1 complex", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0009306 protein secretion;GO:0001657 ureteric bud development;GO:0019221 cytokine-mediated signaling pathway;GO:2000672 negative regulation of motor neuron apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1ML91-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLA7-1", "uniprot_id": "F1MLA7_BOVIN", "mass": 543273.0, "length": 5146, "protein_name": "SCO-spondin", "gene_name": "SSPO", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SSPO", "gene_names_refseq": "", "protein_names_uniprotkb": "SCO-spondin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5173214)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the modulation of neuronal aggregation. May be involved in developmental events during the formation of the central nervous system., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030414 peptidase inhibitor activity;GO:0005201 extracellular matrix structural constituent", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLA7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLB4-1", "uniprot_id": "DAAF3_BOVIN", "mass": 59563.0, "length": 544, "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "DNAAF3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DNAAF3", "gene_names_refseq": "", "protein_names_uniprotkb": "Dynein axonemal assembly factor 3", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1MKE1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0120293 dynein axonemal particle", "go_biological_process": "GO:0044458 motile cilium assembly;GO:0070286 axonemal dynein complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MLB4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLB5-1", "uniprot_id": "F1MLB5_BOVIN", "mass": 27422.0, "length": 255, "protein_name": "Kallikrein-4", "gene_name": "KLK4", "organism": "Bovine", "refseq_name": "kallikrein-4 precursor", "refseq_ac": "NP_001192550", "gene_names_uniprotkb": "KLK4", "gene_names_refseq": "KLK4; KLNB1", "protein_names_uniprotkb": "Kallikrein-4; Enamel matrix serine proteinase 1; Kallikrein-like protein 1; Serine protease 17", "protein_names_refseq": "kallikrein B1; kallikrein-4 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:507800)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Has a major role in enamel formation. Required during the maturation stage of tooth development for clearance of enamel proteins and normal structural patterning of the crystalline matrix., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1R3UCL7", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0030141 secretory granule", "go_biological_process": "GO:0006508 proteolysis;GO:0022617 extracellular matrix disassembly;GO:0031214 biomineral tissue development;GO:0051604 protein maturation;GO:0097186 amelogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLB5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLF2-1", "uniprot_id": "F1MLF2_BOVIN", "mass": 34326.0, "length": 310, "protein_name": "Olfactory receptor", "gene_name": "OR8S27", "organism": "Bovine", "refseq_name": "olfactory receptor family 8 subfamily S member 27", "refseq_ac": "NP_001376711", "gene_names_uniprotkb": "OR8S27", "gene_names_refseq": "OR8S27", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 8S1; olfactory receptor family 8 subfamily S member 27", "tax_id": 9913, "disease": "", "pathway": " (bta:506992)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLF2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLJ1-1", "uniprot_id": "F1MLJ1_BOVIN", "mass": 90396.0, "length": 818, "protein_name": "Protocadherin beta-1", "gene_name": "PCDHB1", "organism": "Bovine", "refseq_name": "protocadherin beta-1 isoform X1", "refseq_ac": "XP_005209567", "gene_names_uniprotkb": "PCDHB1", "gene_names_refseq": "PCDHB1", "protein_names_uniprotkb": "Protocadherin beta-1", "protein_names_refseq": "protocadherin beta-1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:504206)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLJ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLL3-1", "uniprot_id": "F1MLL3_BOVIN", "mass": 37500.0, "length": 330, "protein_name": "Ras related dexamethasone induced 1", "gene_name": "RASD1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RASD1", "gene_names_refseq": "", "protein_names_uniprotkb": "Ras related dexamethasone induced 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031681 G-protein beta-subunit binding;GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016529 sarcoplasmic reticulum", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLL3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLM0-1", "uniprot_id": "F1MLM0_BOVIN", "mass": 34785.0, "length": 309, "protein_name": "Olfactory receptor", "gene_name": "OR52AB10", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "OR52AB10; OR52AB9", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:519176)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLM0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLM3-1", "uniprot_id": "F1MLM3_BOVIN", "mass": 111581.0, "length": 983, "protein_name": "Nonsense-mediated mRNA decay factor", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Nonsense-mediated mRNA decay factor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042162 telomeric DNA binding;GO:0070034 telomerase RNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005697 telomerase holoenzyme complex", "go_biological_process": "GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLM3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLP7-1", "uniprot_id": "F1MLP7_BOVIN", "mass": 39352.0, "length": 358, "protein_name": "U5 small nuclear ribonucleoprotein 40 kDa protein", "gene_name": "SNRNP40", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SNRNP40", "gene_names_refseq": "", "protein_names_uniprotkb": "U5 small nuclear ribonucleoprotein 40 kDa protein; WD repeat-containing protein 57", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-72163); (R-BTA-72165)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for pre-mRNA splicing as component of the activated spliceosome. Component of the U5 small nuclear ribonucleoprotein (snRNP) complex and the U4/U6-U5 tri-snRNP complex, building blocks of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016607 nuclear speck;GO:0071013 catalytic step 2 spliceosome;GO:0071007 U2-type catalytic step 2 spliceosome;GO:0005682 U5 snRNP", "go_biological_process": "GO:0000375 RNA splicing, via transesterification reactions;GO:0006397 mRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLP7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLQ1-1", "uniprot_id": "F1MLQ1_BOVIN", "mass": 14213.0, "length": 130, "protein_name": "Histone H2A", "gene_name": "LOC524236", "organism": "Bovine", "refseq_name": "histone H2A type 1-B", "refseq_ac": "XP_059733687", "gene_names_uniprotkb": "LOC524236", "gene_names_refseq": "LOC524236", "protein_names_uniprotkb": "Histone H2A", "protein_names_refseq": "histone H2A type 1-B", "tax_id": 9913, "disease": "", "pathway": " (bta:524236)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, 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"LOC616002", "gene_names_refseq": "LOC616002", "protein_names_uniprotkb": "Sushi domain-containing protein", "protein_names_refseq": "membrane cofactor protein isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:616002)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0045959 negative regulation of complement activation, classical pathway;GO:0002456 T cell mediated immunity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLR1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLR3-1", "uniprot_id": "F1MLR3_BOVIN", "mass": 143879.0, "length": 1294, "protein_name": "Astrotactin 1", "gene_name": "ASTN1", "organism": "Bovine", "refseq_name": "astrotactin-1 isoform X1", "refseq_ac": "XP_024832630", "gene_names_uniprotkb": "ASTN1", "gene_names_refseq": "ASTN1", "protein_names_uniprotkb": "Astrotactin 1", "protein_names_refseq": "astrotactin-1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:536162)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, 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"protein_name": "Zinc finger protein 541", "gene_name": "ZNF541", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ZNF541", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein 541", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005667 transcription regulator complex;GO:0000118 histone deacetylase complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLU0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLU6-1", "uniprot_id": "F1MLU6_BOVIN", "mass": 63380.0, "length": 612, "protein_name": "Multiple epidermal growth factor-like domains protein 9", "gene_name": "MEGF9", "organism": "Bovine", "refseq_name": "multiple epidermal growth factor-like domains protein 9", "refseq_ac": "XP_003586493", "gene_names_uniprotkb": "MEGF9", "gene_names_refseq": "MEGF9", "protein_names_uniprotkb": "Multiple epidermal growth factor-like domains protein 9; Epidermal growth factor-like protein 5", "protein_names_refseq": "multiple epidermal growth factor-like domains protein 9", "tax_id": 9913, "disease": "", "pathway": " (bta:533820)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0043256 laminin complex", "go_biological_process": "GO:0016477 cell migration;GO:0009887 animal organ morphogenesis;GO:0034446 substrate adhesion-dependent cell spreading;GO:0007411 axon guidance;GO:0009888 tissue development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLU6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLV4-1", "uniprot_id": "F1MLV4_BOVIN", "mass": 15687.0, "length": 138, "protein_name": "Histone H3-like centromeric protein A", "gene_name": "CENPA", "organism": "Bovine", "refseq_name": "histone H3-like centromeric protein A", "refseq_ac": "NP_001192309", "gene_names_uniprotkb": "CENPA", "gene_names_refseq": "CENPA", "protein_names_uniprotkb": "Histone H3-like centromeric protein A; Centromere protein A", "protein_names_refseq": "histone H3-like centromeric protein A", "tax_id": 9913, "disease": "", "pathway": " (bta:613898)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin that serves as an assembly site for the inner kinetochore. The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. Required for recruitment and assembly of kinetochore proteins, and as a consequence required for progress through mitosis, chromosome segregation and cytokinesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000779 condensed chromosome, centromeric region;GO:0000786 nucleosome;GO:0061638 CENP-A containing chromatin", "go_biological_process": "GO:0071459 protein localization to chromosome, centromeric region", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLV4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLW4-1", "uniprot_id": "F1MLW4_BOVIN", "mass": 139657.0, "length": 1286, "protein_name": "Retinol-binding protein 3", "gene_name": "RBP3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RBP3", "gene_names_refseq": "", "protein_names_uniprotkb": "Retinol-binding protein 3; Interphotoreceptor retinoid-binding protein; Interstitial retinol-binding protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2187335); (R-BTA-2453902)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019841 retinol binding;GO:0016918 retinal binding;GO:0008236 serine-type peptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0090658 cone matrix sheath", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLW4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLX1-1", "uniprot_id": "F1MLX1_BOVIN", "mass": 19532.0, "length": 172, "protein_name": "Mitochondrial translation release factor in rescue", "gene_name": "MTRFR", "organism": "Bovine", "refseq_name": "mitochondrial translation release factor in rescue isoform X1", "refseq_ac": "XP_002694521", "gene_names_uniprotkb": "MTRFR", "gene_names_refseq": "MTRFR", "protein_names_uniprotkb": "Mitochondrial translation release factor in rescue", "protein_names_refseq": "mitochondrial translation release factor in rescue isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:507595)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation. As heterodimer with MTRES1, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes. Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000049 tRNA binding;GO:0003747 translation release factor activity;GO:0043023 ribosomal large subunit binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLX1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLY3-1", "uniprot_id": "F1MLY3_BOVIN", "mass": 62894.0, "length": 581, "protein_name": "5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase", "gene_name": "DCP1B", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DCP1B", "gene_names_refseq": "", "protein_names_uniprotkb": "5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase; 3.6.1.62", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-430039)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.1.62;3.6.1.64;3.6.1.59;3.6.1.52;3.6.1.10;3.6.1.61;3.6.4.13", "go_molecular_function": "GO:0003729 mRNA binding;GO:0008047 enzyme activator activity;GO:0140933 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000932 P-body", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLY3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLZ2-1", "uniprot_id": "F1MLZ2_BOVIN", "mass": 73808.0, "length": 681, "protein_name": "Phosphate transporter", "gene_name": "SLC20A1", "organism": "Bovine", "refseq_name": "sodium-dependent phosphate transporter 1", "refseq_ac": "NP_001178114", "gene_names_uniprotkb": "SLC20A1", "gene_names_refseq": "SLC20A1", "protein_names_uniprotkb": "Phosphate transporter", "protein_names_refseq": "sodium-dependent phosphate transporter 1", "tax_id": 9913, "disease": "", "pathway": " (bta:514255); (R-BTA-427652)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Sodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. Essential for cell proliferation but this function is independent of its phosphate transporter activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005315 phosphate transmembrane transporter activity;GO:0005436 sodium:phosphate symporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0008283 cell population proliferation;GO:0035435 phosphate ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLZ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MM02-1", "uniprot_id": "F1MM02_BOVIN", "mass": 22916.0, "length": 219, "protein_name": "Dynein light chain Tctex-type 4", "gene_name": "DYNLT4", "organism": "Bovine", "refseq_name": "dynein light chain Tctex-type 4", "refseq_ac": "XP_002686478", "gene_names_uniprotkb": "DYNLT4", "gene_names_refseq": "DYNLT4", "protein_names_uniprotkb": "Dynein light chain Tctex-type 4", "protein_names_refseq": "dynein light chain Tctex-type 4", "tax_id": 9913, "disease": "", "pathway": " (bta:516323)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008157 protein phosphatase 1 binding;GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0001669 acrosomal vesicle;GO:0005815 microtubule organizing center;GO:0036126 sperm flagellum", "go_biological_process": "GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MM02-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MM20-1", "uniprot_id": "F1MM20_BOVIN", "mass": 39862.0, "length": 354, "protein_name": "Coiled-coil domain-containing protein 86", "gene_name": "CCDC86", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CCDC86", "gene_names_refseq": "", "protein_names_uniprotkb": "Coiled-coil domain-containing protein 86", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for proper chromosome segregation during mitosis and error-free mitotic progression., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, 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"uniprot_canonical_ac": "F1MM26-1", "uniprot_id": "F1MM26_BOVIN", "mass": 80088.0, "length": 734, "protein_name": "Adenosine deaminase RNA specific B2 (inactive)", "gene_name": "ADARB2", "organism": "Bovine", "refseq_name": "inactive double-stranded RNA-specific editase B2", "refseq_ac": "NP_001179517", "gene_names_uniprotkb": "ADARB2", "gene_names_refseq": "ADARB2", "protein_names_uniprotkb": "Adenosine deaminase RNA specific B2 (inactive)", "protein_names_refseq": "adenosine deaminase, RNA-specific, B2 (RED2 homolog rat); adenosine deaminase, RNA-specific, B2 (non-functional); inactive double-stranded RNA-specific editase B2", "tax_id": 9913, "disease": "", "pathway": " (bta:524061)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, 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tRNA-specific adenosine deaminase activity;GO:0046872 metal ion binding;GO:0003725 double-stranded RNA binding;GO:0003726 double-stranded RNA adenosine deaminase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006396 RNA processing;GO:0070935 3'-UTR-mediated mRNA stabilization;GO:0090367 negative regulation of mRNA modification;GO:0006382 adenosine to inosine editing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MM26-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MM29-1", "uniprot_id": "F1MM29_BOVIN", "mass": 26550.0, "length": 239, "protein_name": "small monomeric GTPase", "gene_name": "RASL11A", "organism": "Bovine", "refseq_name": "ras-like protein family member 11A", "refseq_ac": "XP_005213886", "gene_names_uniprotkb": "RASL11A", "gene_names_refseq": "RASL11A", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "ras-like protein 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"protein_names_uniprotkb": "Sulfhydryl oxidase; 1.8.3.2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.3.2", "go_molecular_function": "GO:0071949 FAD binding;GO:0016971 flavin-dependent sulfhydryl oxidase activity;GO:0003756 protein disulfide isomerase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0070062 extracellular exosome", "go_biological_process": "GO:0085029 extracellular matrix assembly;GO:0016242 negative regulation of macroautophagy", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MM32-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MM48-1", "uniprot_id": "F1MM48_BOVIN", "mass": 63930.0, "length": 580, "protein_name": "Interleukin-10 receptor subunit alpha", "gene_name": "IL10RA", "organism": "Bovine", "refseq_name": "interleukin-10 receptor subunit alpha isoform X1", "refseq_ac": "XP_005215888", "gene_names_uniprotkb": "IL10RA", "gene_names_refseq": "IL10RA", "protein_names_uniprotkb": "Interleukin-10 receptor subunit alpha; CDw210a; Interleukin-10 receptor subunit 1", "protein_names_refseq": "interleukin-10 receptor subunit alpha isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-6783783)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cell surface receptor for the cytokine IL10 that participates in IL10-mediated anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Upon binding to IL10, induces a conformational change in IL10RB, allowing IL10RB to bind IL10 as well. In turn, the heterotetrameric assembly complex, composed of two subunits of IL10RA and IL10RB, activates the kinases JAK1 and TYK2 that are constitutively associated with IL10RA and IL10RB respectively. These kinases then phosphorylate specific tyrosine residues in the intracellular domain in IL10RA leading to the recruitment and subsequent phosphorylation of STAT3. Once phosphorylated, STAT3 homodimerizes, translocates to the nucleus and activates the expression of anti-inflammatory genes. 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The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MM67-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MM78-1", "uniprot_id": "F1MM78_BOVIN", "mass": 78698.0, "length": 707, "protein_name": "Zinc finger CCHC domain-containing protein 8", "gene_name": "ZCCHC8", "organism": "Bovine", "refseq_name": "zinc finger CCHC domain-containing protein 8", "refseq_ac": "NP_001192619", "gene_names_uniprotkb": "ZCCHC8", "gene_names_refseq": "ZCCHC8", "protein_names_uniprotkb": "Zinc finger CCHC domain-containing protein 8; TRAMP-like complex RNA-binding factor ZCCHC8", "protein_names_refseq": "zinc finger CCHC domain-containing protein 8", "tax_id": 9913, "disease": "", "pathway": " (bta:539598); (R-BTA-9930044)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex that is involved in the surveillance and turnover of aberrant transcripts and non-coding RNAs. NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. May be involved in pre-mRNA splicing. It is required for 3'-end maturation of telomerase RNA component (TERC), TERC 3'-end targeting to the nuclear RNA exosome, and for telomerase function., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0071013 catalytic step 2 spliceosome;GO:0031499 TRAMP complex", "go_biological_process": "GO:0006396 RNA processing;GO:0031124 mRNA 3'-end processing;GO:0180034 co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MM78-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MM83-1", "uniprot_id": "F1MM83_BOVIN", "mass": 27531.0, "length": 258, "protein_name": "6-phosphogluconolactonase", "gene_name": "PGLS", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PGLS", "gene_names_refseq": "", "protein_names_uniprotkb": "6-phosphogluconolactonase; 3.1.1.31; 6PGL", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-71336)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, 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"F1MM90_BOVIN", "mass": 30300.0, "length": 259, "protein_name": "Polycomb group RING finger protein 1", "gene_name": "PCGF1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PCGF1", "gene_names_refseq": "", "protein_names_uniprotkb": "Polycomb group RING finger protein 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, 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"reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019911 structural constituent of myelin sheath", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0042552 myelination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MM95-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MMA8-1", "uniprot_id": "F1MMA8_BOVIN", "mass": 33594.0, "length": 298, "protein_name": "Intestine-specific homeobox", "gene_name": "ISX", "organism": "Bovine", "refseq_name": "intestine-specific homeobox", "refseq_ac": "XP_010803623", "gene_names_uniprotkb": "ISX", "gene_names_refseq": "ISX", "protein_names_uniprotkb": "Intestine-specific homeobox", "protein_names_refseq": "intestine-specific homeobox", "tax_id": 9913, "disease": "", "pathway": " (bta:506388)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCO1 expression in the intestine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0048666 neuron development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MMA8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MMF6-1", "uniprot_id": "F1MMF6_BOVIN", "mass": 19233.0, "length": 175, "protein_name": "H1.9 linker histone", "gene_name": "H1-9", "organism": "Bovine", "refseq_name": "histone linker H1 domain, spermatid-specific 1", "refseq_ac": "NP_001290338", "gene_names_uniprotkb": "H1-9", "gene_names_refseq": "H1-9; HILS1", "protein_names_uniprotkb": "H1.9 linker histone", "protein_names_refseq": "histone linker H1 domain, spermatid-specific 1; spermatid-specific linker histone H1-like protein", "tax_id": 9913, "disease": "", "pathway": " (bta:615867)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0031492 nucleosomal DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0006334 nucleosome assembly;GO:0030261 chromosome condensation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MMF6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MMG4-1", "uniprot_id": "F1MMG4_BOVIN", "mass": 52062.0, "length": 455, "protein_name": "Tripartite motif-containing protein 64-like", "gene_name": "LOC520034", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC520034", "gene_names_refseq": "", "protein_names_uniprotkb": "Tripartite motif-containing protein 64-like", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045087 innate immune response;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MMG4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MML8-1", "uniprot_id": "F1MML8_BOVIN", "mass": 49159.0, "length": 450, "protein_name": "Histamine H3 receptor", "gene_name": "HRH3", "organism": "Bovine", "refseq_name": "histamine H3 receptor", "refseq_ac": "XP_024856904", "gene_names_uniprotkb": "HRH3", "gene_names_refseq": "HRH3", "protein_names_uniprotkb": "Histamine H3 receptor", "protein_names_refseq": "histamine H3 receptor", "tax_id": 9913, "disease": "", "pathway": " (bta:789851); (R-BTA-390650)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030594 neurotransmitter receptor activity;GO:0004969 histamine receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:0007197 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MML8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MMM8-1", "uniprot_id": "F1MMM8_BOVIN", "mass": 33305.0, "length": 292, "protein_name": "Large ribosomal subunit protein bL19m", "gene_name": "MRPL19", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MRPL19", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein bL19m; 39S ribosomal protein L19, mitochondrial", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5389840); (R-BTA-5419276); (R-BTA-9937383)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0031090 organelle membrane", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MMM8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MMN3-1", "uniprot_id": "F1MMN3_BOVIN", "mass": 100584.0, "length": 872, "protein_name": "[heparan sulfate]-glucosamine N-sulfotransferase", "gene_name": "NDST4", "organism": "Bovine", "refseq_name": "bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4", "refseq_ac": "NP_001179602", "gene_names_uniprotkb": "NDST4", "gene_names_refseq": "NDST4", "protein_names_uniprotkb": "[heparan sulfate]-glucosamine N-sulfotransferase; 2.8.2.8", "protein_names_refseq": "N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4; bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4", "tax_id": 9913, "disease": "", "pathway": " (bta:529260); (R-BTA-2022928)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "G3N2T1", "ec_number_list": "2.8.2.8", "go_molecular_function": "GO:0019213 deacetylase activity;GO:0015016 heparan sulfate N-sulfotransferase activity;GO:0050119 N-acetylglucosamine deacetylase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0030210 heparin proteoglycan biosynthetic process;GO:0015012 heparan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MMN3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MMN9-1", "uniprot_id": "F1MMN9_BOVIN", "mass": 91570.0, "length": 816, "protein_name": "Villin-1", "gene_name": "AVIL", "organism": "Bovine", "refseq_name": "advillin", "refseq_ac": "NP_001179458", "gene_names_uniprotkb": "AVIL", "gene_names_refseq": "AVIL", "protein_names_uniprotkb": "Villin-1", "protein_names_refseq": "advillin", "tax_id": 9913, "disease": "", "pathway": " (bta:520771)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Epithelial cell-specific Ca(2+)-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments. Plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Binds phosphatidylinositol 4,5-bisphosphate (PIP2) and lysophosphatidic acid (LPA); binds LPA with higher affinity than PIP2. Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities. Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity. Regulates the intestinal epithelial cell morphology, cell invasion, cell migration and apoptosis. Protects against apoptosis induced by dextran sodium sulfate (DSS) in the gastrointestinal epithelium. Appears to regulate cell death by maintaining mitochondrial integrity. Enhances hepatocyte growth factor (HGF)-induced epithelial cell motility, chemotaxis and wound repair., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0051015 actin filament binding;GO:0071933 Arp2/3 complex binding", "go_cellular_component": "GO:0005884 actin filament;GO:0005925 focal adhesion;GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium;GO:0001726 ruffle", "go_biological_process": "GO:0010976 positive regulation of neuron projection development;GO:0051016 barbed-end actin filament capping;GO:0008154 actin polymerization or depolymerization;GO:0060271 cilium assembly;GO:0051014 actin filament severing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MMN9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MMT9-1", "uniprot_id": "F1MMT9_BOVIN", "mass": 20029.0, "length": 175, "protein_name": "Ferritin", "gene_name": "LOC104970886", "organism": "Bovine", "refseq_name": "ferritin light chain-like", "refseq_ac": "XP_059744044", "gene_names_uniprotkb": "LOC104970886", "gene_names_refseq": "LOC104970886", "protein_names_uniprotkb": "Ferritin", "protein_names_refseq": "ferritin light chain-like", "tax_id": 9913, "disease": "", "pathway": " (bta:104970886)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Delivery to lysosomes by the cargo receptor NCOA4 for autophagic degradation and release or iron., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008198 ferrous iron binding;GO:0008199 ferric iron binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031410 cytoplasmic vesicle;GO:0044754 autolysosome", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0006826 iron ion transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MMT9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MMU0-1", "uniprot_id": "F1MMU0_BOVIN", "mass": 35548.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "OR6C280", "organism": "Bovine", "refseq_name": "olfactory receptor family 6 subfamily C member 280", "refseq_ac": "NP_001376719", "gene_names_uniprotkb": "OR6C280", "gene_names_refseq": "OR6C280", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 6C2; olfactory receptor family 6 subfamily C member 280", "tax_id": 9913, "disease": "", "pathway": " (bta:507560)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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Interaction with RARRES2 initiates activation of G proteins G(i)/G(o) and beta-arrestin pathways inducing cellular responses via second messenger pathways such as intracellular calcium mobilization, phosphorylation of MAP kinases MAPK1/MAPK3 (ERK1/2), TYRO3, MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. 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May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0016015 morphogen activity;GO:0036122 BMP binding;GO:0140311 protein sequestering activity;GO:0141069 receptor ligand inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0038098 sequestering of BMP from receptor via BMP binding;GO:0090027 negative regulation of monocyte chemotaxis;GO:0007399 nervous system development;GO:0048263 determination of dorsal identity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MNJ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MNN1-1", "uniprot_id": "F1MNN1_BOVIN", "mass": 69599.0, "length": 601, "protein_name": "HAUS augmin like complex subunit 3", "gene_name": "HAUS3", "organism": "Bovine", "refseq_name": "HAUS augmin-like complex subunit 3 isoform X1", "refseq_ac": "XP_059743663", "gene_names_uniprotkb": "HAUS3", "gene_names_refseq": "HAUS3", "protein_names_uniprotkb": "HAUS augmin like complex subunit 3", "protein_names_refseq": "HAUS augmin-like complex subunit 3 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2565942); (R-BTA-380259); (R-BTA-380270); (R-BTA-380284); (R-BTA-380320); (R-BTA-5620912); (R-BTA-8854518)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0005815 microtubule organizing center;GO:0036064 ciliary basal body;GO:0070652 HAUS complex;GO:1990498 mitotic spindle microtubule", "go_biological_process": "GO:0051301 cell division;GO:0007098 centrosome cycle;GO:0051225 spindle assembly;GO:0031023 microtubule organizing center organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MNN1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MNP1-1", "uniprot_id": "F1MNP1_BOVIN", "mass": 35736.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "OR5I1", "organism": "Bovine", "refseq_name": "olfactory receptor 5I1", "refseq_ac": "NP_001377088", "gene_names_uniprotkb": "OR5I1", "gene_names_refseq": "OR5I1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 5I1", "tax_id": 9913, "disease": "", "pathway": " (bta:538864)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion. 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plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MPN9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MPP2-1", "uniprot_id": "F1MPP2_BOVIN", "mass": 29050.0, "length": 282, "protein_name": "Insulin-like growth factor-binding protein 7", "gene_name": "IGFBP7", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IGFBP7", "gene_names_refseq": "", "protein_names_uniprotkb": "Insulin-like growth factor-binding protein 7; MAC25 protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-381426); (R-BTA-8957275)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds IGF1 and IGF2 with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. Acts as a ligand for CD93 to play a role in angiogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005520 insulin-like growth factor binding;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0001525 angiogenesis;GO:0007155 cell adhesion;GO:0001558 regulation of cell growth;GO:0009966 regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MPP2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MPP7-1", "uniprot_id": "F1MPP7_BOVIN", "mass": 64937.0, "length": 577, "protein_name": "medium-chain acyl-CoA ligase", "gene_name": "ACSM1", "organism": "Bovine", "refseq_name": "acyl-coenzyme A synthetase ACSM1, mitochondrial isoform X1", "refseq_ac": "XP_005224748", "gene_names_uniprotkb": "ACSM1", "gene_names_refseq": "ACSM1; BUCS1", "protein_names_uniprotkb": "medium-chain acyl-CoA ligase; 6.2.1.2", "protein_names_refseq": "acyl-coenzyme A synthetase ACSM1, mitochondrial isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-177135); (R-BTA-177162)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.2.1.2;6.2.1.25", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004467 long-chain fatty acid-CoA ligase activity;GO:0102391 decanoate-CoA ligase activity;GO:0004321 fatty-acyl-CoA synthase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006637 acyl-CoA metabolic process;GO:0006633 fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MPP7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MPT2-1", "uniprot_id": "F1MPT2_BOVIN", "mass": 109874.0, "length": 964, "protein_name": "Glycoside hydrolase family 38 central domain-containing protein", "gene_name": "LOC781835", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC781835", "gene_names_refseq": "", "protein_names_uniprotkb": "Glycoside hydrolase family 38 central domain-containing protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004559 alpha-mannosidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006013 mannose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MPT2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MPT4-1", "uniprot_id": "F1MPT4_BOVIN", "mass": 241273.0, "length": 2197, "protein_name": "Sidekick cell adhesion molecule 2", "gene_name": "SDK2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SDK2", "gene_names_refseq": "", "protein_names_uniprotkb": "Sidekick cell adhesion molecule 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:100336619); (R-BTA-373756)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0045202 synapse", "go_biological_process": "GO:0007416 synapse assembly;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0010842 retina layer formation;GO:0060219 camera-type eye photoreceptor cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MPT4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MPV3-1", "uniprot_id": "F1MPV3_BOVIN", "mass": 73719.0, "length": 635, "protein_name": "RalA-binding protein 1", "gene_name": "RALBP1", "organism": "Bovine", "refseq_name": "ralA-binding protein 1", "refseq_ac": "XP_002697791", "gene_names_uniprotkb": "RALBP1", "gene_names_refseq": "RALBP1", "protein_names_uniprotkb": "RalA-binding protein 1; 7.6.2.2; 7.6.2.3; Dinitrophenyl S-glutathione ATPase; Ral-interacting protein 1", "protein_names_refseq": "ralA-binding protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:523324)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Could also function as a primary ATP-dependent active transporter for glutathione conjugates of electrophiles. May also actively catalyze the efflux of a wide range of substrates including xenobiotics like doxorubicin (DOX) contributing to cell multidrug resistance., [UniProtKB, UniProtKB]; Multifunctional protein that functions as a downstream effector of RALA and RALB. As a GTPase-activating protein/GAP can inactivate CDC42 and RAC1 by stimulating their GTPase activity. As part of the Ral signaling pathway, may also regulate ligand-dependent EGF and insulin receptors-mediated endocytosis. During mitosis, may act as a scaffold protein in the phosphorylation of EPSIN/EPN1 by the mitotic kinase cyclin B-CDK1, preventing endocytosis during that phase of the cell cycle. During mitosis, also controls mitochondrial fission as an effector of RALA. Recruited to mitochondrion by RALA, acts as a scaffold to foster the mitotic kinase cyclin B-CDK1-mediated phosphorylation and activation of DNM1L., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "7.6.2.2;7.6.2.3;7.6.2.-", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005524 ATP binding;GO:0008559 ABC-type xenobiotic transporter activity;GO:0031267 small GTPase binding;GO:0015431 ABC-type glutathione S-conjugate transporter activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0016604 nuclear body", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction;GO:0090141 positive regulation of mitochondrial fission;GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane;GO:1900753 doxorubicin transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MPV3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MPV5-1", "uniprot_id": "F1MPV5_BOVIN", "mass": 101685.0, "length": 916, "protein_name": "Nuclear transcription factor, X-box binding like 1", "gene_name": "NFXL1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NFXL1", "gene_names_refseq": "", "protein_names_uniprotkb": "Nuclear transcription factor, X-box binding like 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MPV5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MPV7-1", "uniprot_id": "F1MPV7_BOVIN", "mass": 54199.0, "length": 477, "protein_name": "Delayed-rectifier potassium channel regulatory subunit KCNS2", "gene_name": "KCNS2", "organism": "Bovine", "refseq_name": "delayed-rectifier potassium channel regulatory subunit KCNS2", "refseq_ac": "XP_015330007", "gene_names_uniprotkb": "KCNS2", "gene_names_refseq": "KCNS2", "protein_names_uniprotkb": "Delayed-rectifier potassium channel regulatory subunit KCNS2; Delayed-rectifier K(+) channel alpha subunit 2; Delayed-rectifier potassium channel subunit Kv9.2; Potassium voltage-gated channel subfamily S member 2", "protein_names_refseq": "delayed-rectifier potassium channel regulatory subunit KCNS2", "tax_id": 9913, "disease": "", "pathway": " (bta:514860); (R-BTA-1296072)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Potassium channel regulatory subunit that modulate the delayed rectifier voltage-gated potassium channel activity of KCNB1 and KCNB2 by altering their kinetics, expression levels, and shifting the half-inactivation potential to more polarized values. While it does not form functional channels on its own, it can form functional heterotetrameric channels with KCNB1 and KCNB2. Each regulatory subunit has unique regulatory properties that can lead to extensive inhibition, significant changes in kinetics, and/or substantial shifts in the voltage dependencies of the inactivation process., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015459 potassium channel regulator activity;GO:0005249 voltage-gated potassium channel activity", "go_cellular_component": "GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm;GO:0008076 voltage-gated potassium channel complex", "go_biological_process": "GO:1901379 regulation of potassium ion transmembrane transport;GO:0051260 protein homooligomerization;GO:0001508 action potential;GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MPV7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MPW7-1", "uniprot_id": "F1MPW7_BOVIN", "mass": 203796.0, "length": 1889, "protein_name": "Nucleoporin 210", "gene_name": "NUP210", "organism": "Bovine", "refseq_name": "nuclear pore membrane glycoprotein 210 precursor", "refseq_ac": "NP_001178390", "gene_names_uniprotkb": "NUP210", "gene_names_refseq": "NUP210", "protein_names_uniprotkb": "Nucleoporin 210", "protein_names_refseq": "nuclear pore membrane glycoprotein 210 precursor; nucleoporin 210kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:100125264); (R-BTA-159227); (R-BTA-159230); (R-BTA-159231); (R-BTA-159236); (R-BTA-1855170); (R-BTA-1855196); (R-BTA-1855229); (R-BTA-191859); (R-BTA-3108214); (R-BTA-3232142); (R-BTA-3301854); (R-BTA-3371453); (R-BTA-4085377); (R-BTA-4551638); (R-BTA-4570464); (R-BTA-4615885)", "pathway_count": 17, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005643 nuclear pore;GO:0031965 nuclear membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MPW7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MPW8-1", "uniprot_id": "F1MPW8_BOVIN", "mass": 395179.0, "length": 3596, "protein_name": "Zinc finger homeobox protein 4", "gene_name": "ZFHX4", "organism": "Bovine", "refseq_name": "zinc finger homeobox protein 4 isoform X2", "refseq_ac": "XP_010810373", "gene_names_uniprotkb": "ZFHX4", "gene_names_refseq": "ZFHX4", "protein_names_uniprotkb": "Zinc finger homeobox protein 4; Zinc finger homeodomain protein 4", "protein_names_refseq": "zinc finger homeobox protein 4 isoform X2", "tax_id": 9913, "disease": "", "pathway": " (bta:539762)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in neural and muscle differentiation. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MPX9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MPY1-1", "uniprot_id": "F1MPY1_BOVIN", "mass": 36386.0, "length": 322, "protein_name": "Olfactory receptor", "gene_name": "OR2T3B", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "OR2T3B", "gene_names_refseq": "", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MPY1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MPZ4-1", "uniprot_id": "F1MPZ4_BOVIN", "mass": 27826.0, "length": 249, "protein_name": "Interleukin-1 receptor antagonist protein", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Interleukin-1 receptor antagonist protein; IL1 inhibitor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. 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"go_biological_process": "GO:0032981 mitochondrial respiratory chain complex I assembly;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MQP4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MQP6-1", "uniprot_id": "F1MQP6_BOVIN", "mass": 367537.0, "length": 3360, "protein_name": "Dachsous cadherin-related 2", "gene_name": "LOC539323", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC539323", "gene_names_refseq": "", "protein_names_uniprotkb": "Dachsous cadherin-related 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005911 cell-cell junction", "go_biological_process": "GO:0060429 epithelium development;GO:0048729 tissue morphogenesis;GO:0030154 cell differentiation;GO:0098609 cell-cell adhesion;GO:0003007 heart morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MQP6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MQQ3-1", "uniprot_id": "F1MQQ3_BOVIN", "mass": 37297.0, "length": 340, "protein_name": "Olfactory receptor", "gene_name": "OR52I11", "organism": "Bovine", "refseq_name": "olfactory receptor 52I1", "refseq_ac": "XP_015330239", "gene_names_uniprotkb": "OR52I11", "gene_names_refseq": "OR52I11", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 52I1", "tax_id": 9913, "disease": "", "pathway": " (bta:510351)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0071396 cellular response to lipid", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MQQ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MQU1-1", "uniprot_id": "F1MQU1_BOVIN", "mass": 36729.0, "length": 324, "protein_name": "Olfactory receptor", "gene_name": "OR2B11", "organism": "Bovine", "refseq_name": "olfactory receptor family 2 subfamily B member 11", "refseq_ac": "NP_001376827", "gene_names_uniprotkb": "OR2B11", "gene_names_refseq": "OR2B11", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor family 2 subfamily B member 11", "tax_id": 9913, "disease": "", "pathway": " (bta:512138); (R-BTA-381753)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MQU1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MQW8-1", "uniprot_id": "F1MQW8_BOVIN", "mass": 53593.0, "length": 463, "protein_name": "Interferon induced protein with tetratricopeptide repeats 2", "gene_name": "IFIT2", "organism": "Bovine", "refseq_name": "interferon-induced protein with tetratricopeptide repeats 2", "refseq_ac": "XP_002698402", "gene_names_uniprotkb": "IFIT2", "gene_names_refseq": "IFIT2", "protein_names_uniprotkb": "Interferon induced protein with tetratricopeptide repeats 2", "protein_names_refseq": "interferon-induced protein with tetratricopeptide repeats 2", "tax_id": 9913, "disease": "", "pathway": " (bta:527528)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0071345 cellular response to cytokine stimulus;GO:0140374 antiviral innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MQW8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MR01-1", "uniprot_id": "F1MR01_BOVIN", "mass": 16303.0, "length": 151, "protein_name": "Small ribosomal subunit protein uS11", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Small ribosomal subunit protein uS11; 40S ribosomal protein S14", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-156827); (R-BTA-1799339); (R-BTA-6791226); (R-BTA-72649); (R-BTA-72689); (R-BTA-72695); (R-BTA-72702); (R-BTA-72706); (R-BTA-975956); (R-BTA-975957); (R-BTA-9954714); (R-BTA-9954716)", "pathway_count": 12, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MR01-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MR22-1", "uniprot_id": "F1MR22_BOVIN", "mass": 82622.0, "length": 757, "protein_name": "Polymeric immunoglobulin receptor", "gene_name": "PIGR", "organism": "Bovine", "refseq_name": "polymeric immunoglobulin receptor precursor", "refseq_ac": "NP_776568", "gene_names_uniprotkb": "PIGR", "gene_names_refseq": "PIGR", "protein_names_uniprotkb": "Polymeric immunoglobulin receptor", "protein_names_refseq": "poly-Ig receptor; polymeric immunoglobulin receptor precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:281401); (R-BTA-6798695)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23395346", "class_list": "", "function": "Mediates selective transcytosis of polymeric IgA and IgM across mucosal epithelial cells. Binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment., [UniProtKB, UniProtKB]; This study evaluated the production of polymeric immunoglobulin receptor and immunoglobulin A in the salivary glands of cattle., [RefSeq, PubMed]; Through its N-linked glycans ensures anchoring of secretory IgA (sIgA) molecules to mucus lining the epithelial surface to neutralize extracellular pathogens. On its own (free form) may act as a non-specific microbial scavenger to prevent pathogen interaction with epithelial cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F6PQI6", "ec_number_list": "", "go_molecular_function": "GO:0001792 polymeric immunoglobulin receptor activity;GO:0004888 transmembrane signaling receptor activity;GO:0001790 polymeric immunoglobulin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0071751 secretory IgA immunoglobulin complex", "go_biological_process": "GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor;GO:0007165 signal transduction;GO:0007173 epidermal growth factor receptor signaling pathway;GO:0043113 receptor clustering;GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MR22-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MR31-1", "uniprot_id": "F1MR31_BOVIN", "mass": 24428.0, "length": 225, "protein_name": "Ornithine decarboxylase antizyme 1", "gene_name": "OAZ1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "OAZ1", "gene_names_refseq": "", "protein_names_uniprotkb": "Ornithine decarboxylase antizyme 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-350562); (R-BTA-351202)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome. Triggers ODC degradation by inducing the exposure of a cryptic proteasome-interacting surface of ODC. Stabilizes AZIN2 by interfering with its ubiquitination. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. Involved in the translocation of AZIN2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008073 ornithine decarboxylase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006596 polyamine biosynthetic process;GO:0075523 viral translational frameshifting", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MR31-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MR51-1", "uniprot_id": "F1MR51_BOVIN", "mass": 35573.0, "length": 313, "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "OR2B3B", "organism": "Bovine", "refseq_name": "putative olfactory receptor 2B3", "refseq_ac": "XP_002697484", "gene_names_uniprotkb": "OR2B3B", "gene_names_refseq": "OR2B3B", "protein_names_uniprotkb": "G-protein coupled receptors family 1 profile domain-containing protein", "protein_names_refseq": "putative olfactory receptor 2B3", "tax_id": 9913, "disease": "", "pathway": " (bta:784652)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MR51-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MR60-1", "uniprot_id": "F1MR60_BOVIN", "mass": 96056.0, "length": 837, "protein_name": "Tuftelin-interacting protein 11", "gene_name": "TFIP11", "organism": "Bovine", "refseq_name": "tuftelin-interacting protein 11 isoform X1", "refseq_ac": "XP_005218116", "gene_names_uniprotkb": "TFIP11", "gene_names_refseq": "STIP; TFIP11", "protein_names_uniprotkb": "Tuftelin-interacting protein 11", "protein_names_refseq": "tuftelin-interacting protein 11 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-72163)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0016607 nuclear speck;GO:0031012 extracellular matrix;GO:0071013 catalytic step 2 spliceosome;GO:0071008 U2-type post-mRNA release spliceosomal complex", "go_biological_process": "GO:0031333 negative regulation of protein-containing complex assembly;GO:0031214 biomineral tissue development;GO:0000390 spliceosomal complex disassembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MR60-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MR67-1", "uniprot_id": "F1MR67_BOVIN", "mass": 139860.0, "length": 1273, "protein_name": "Fibronectin type-III domain-containing protein", "gene_name": "LOC519208", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC519208", "gene_names_refseq": "", "protein_names_uniprotkb": "Fibronectin type-III domain-containing protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MR67-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MR72-1", "uniprot_id": "F1MR72_BOVIN", "mass": 35401.0, "length": 312, "protein_name": "Olfactory receptor", "gene_name": "OR4G2", "organism": "Bovine", "refseq_name": "olfactory receptor family 4 subfamily G member 2", "refseq_ac": "NP_001377363", "gene_names_uniprotkb": "OR4G2", "gene_names_refseq": "OR4G2", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor family 4 subfamily G member 2; olfactory receptor, family 4, subfamily F, member 6-like", "tax_id": 9913, "disease": "", "pathway": " (bta:785683)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MR72-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MR77-1", "uniprot_id": "F1MR77_BOVIN", "mass": 41885.0, "length": 387, "protein_name": "Diencephalon/mesencephalon homeobox protein 1", "gene_name": "DMBX1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DMBX1", "gene_names_refseq": "", "protein_names_uniprotkb": "Diencephalon/mesencephalon homeobox protein 1; 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"protein_names_uniprotkb": "G-protein coupled receptors family 1 profile domain-containing protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, 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Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function. Upon tissue injury, induces UCP2-dependent mitochondrial rewiring that attenuates the generation of reactive oxygen species and preserves the integrity of Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0002113 interleukin-33 binding;GO:0002114 interleukin-33 receptor activity;GO:0016787 hydrolase activity;GO:0004908 interleukin-1 receptor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0032754 positive regulation of interleukin-5 production;GO:0043032 positive regulation of macrophage activation;GO:0006954 inflammatory response;GO:0032689 negative regulation of type II interferon production;GO:0032722 positive regulation of chemokine production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MRU1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MRU4-1", "uniprot_id": "F1MRU4_BOVIN", "mass": 466140.0, "length": 4066, "protein_name": "Dynein axonemal heavy chain 3", "gene_name": "DNAH3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DNAH3", "gene_names_refseq": "", "protein_names_uniprotkb": "Dynein axonemal heavy chain 3; 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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"reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MS80-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MS84-1", "uniprot_id": "F1MS84_BOVIN", "mass": 54876.0, "length": 549, "protein_name": "NOVA alternative splicing regulator 2", "gene_name": "NOVA2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NOVA2", "gene_names_refseq": "", "protein_names_uniprotkb": "NOVA alternative splicing regulator 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, 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"reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:1990825 sequence-specific mRNA binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:1902667 regulation of axon guidance;GO:0000398 mRNA splicing, via spliceosome;GO:0021954 central nervous system neuron development;GO:0000381 regulation of alternative mRNA splicing, via spliceosome;GO:0120163 negative regulation of cold-induced thermogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MS84-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MS90-1", "uniprot_id": "F1MS90_BOVIN", "mass": 59230.0, "length": 554, "protein_name": "Myc proto-oncogene protein", "gene_name": "MYCN", "organism": "Bovine", "refseq_name": "N-myc proto-oncogene protein", "refseq_ac": "XP_002691569", "gene_names_uniprotkb": "MYCN", "gene_names_refseq": "MYCN", "protein_names_uniprotkb": "Myc proto-oncogene protein; Proto-oncogene c-Myc; Transcription factor p64", "protein_names_refseq": "N-myc proto-oncogene protein", "tax_id": 9913, "disease": "", "pathway": " (bta:616888)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release. Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0019900 kinase binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005694 chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010628 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phosducin with its binding partner G protein beta gamma dimer, [RefSeq, PubMed]; Transducin betagamma is a substrate of the ubiquitin-proteasome pathway and is protected following the light-dependent dissociation of transducin alphabetagamma by phosducin, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0001917 photoreceptor inner segment;GO:0001750 photoreceptor outer segment", "go_biological_process": "GO:0007601 visual perception;GO:0008277 regulation of G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1MSE1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSE7-1", "uniprot_id": "F1MSE7_BOVIN", "mass": 92877.0, "length": 847, "protein_name": "Sushi domain containing 2", "gene_name": "SUSD2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SUSD2", "gene_names_refseq": "", "protein_names_uniprotkb": "Sushi domain containing 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSE7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSF6-1", "uniprot_id": "F1MSF6_BOVIN", "mass": 54071.0, "length": 474, "protein_name": "UTP3 small subunit processome component", "gene_name": "UTP3", "organism": "Bovine", "refseq_name": "something about silencing protein 10", "refseq_ac": "XP_005208182", "gene_names_uniprotkb": "UTP3", "gene_names_refseq": "UTP3", "protein_names_uniprotkb": "UTP3 small subunit processome component", "protein_names_refseq": "something about silencing protein 10", "tax_id": 9913, "disease": "", "pathway": " (bta:521106); (R-BTA-6791226)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus;GO:0032040 small-subunit processome", "go_biological_process": "GO:0007420 brain development;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSF6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSG9-1", "uniprot_id": "F1MSG9_BOVIN", "mass": 49584.0, "length": 437, "protein_name": "Transmembrane protease 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"length": 372, "protein_name": "Serine/threonine-protein kinase 17B", "gene_name": "STK17B", "organism": "Bovine", "refseq_name": "serine/threonine-protein kinase 17B isoform X1", "refseq_ac": "XP_005202681", "gene_names_uniprotkb": "STK17B", "gene_names_refseq": "STK17B", "protein_names_uniprotkb": "Serine/threonine-protein kinase 17B; 2.7.11.1; DAP kinase-related apoptosis-inducing protein kinase 2", "protein_names_refseq": "serine/threonine-protein kinase 17B isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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"2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005886 plasma membrane;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0006915 apoptotic process;GO:2000271 positive regulation of fibroblast apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSI1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSI6-1", "uniprot_id": "F1MSI6_BOVIN", "mass": 54561.0, "length": 483, "protein_name": "RNA helicase", "gene_name": "DDX25", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DDX25", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, 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granule;GO:0033391 chromatoid body", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0006417 regulation of translation;GO:0007286 spermatid development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSI6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSL8-1", "uniprot_id": "F1MSL8_BOVIN", "mass": 92030.0, "length": 795, "protein_name": "IQ motif and ubiquitin domain containing", "gene_name": "IQUB", "organism": "Bovine", "refseq_name": "IQ motif and ubiquitin-like domain-containing protein", "refseq_ac": "NP_001193878", "gene_names_uniprotkb": "IQUB", "gene_names_refseq": "IQUB", "protein_names_uniprotkb": "IQ motif and ubiquitin domain containing", "protein_names_refseq": "IQ motif and ubiquitin-like domain-containing protein", "tax_id": 9913, "disease": "", "pathway": " (bta:536449)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "39743588", "class_list": "", "function": "", "predicted_glycosites": 0, 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"glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0001534 radial spoke;GO:0031514 motile cilium;GO:0001669 acrosomal vesicle;GO:0036126 sperm flagellum", "go_biological_process": "GO:0030317 flagellated sperm motility;GO:0060271 cilium assembly;GO:0007618 mating", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MSL8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSM5-1", "uniprot_id": "F1MSM5_BOVIN", "mass": 65346.0, "length": 583, "protein_name": "Mitochondrial poly(A) polymerase", "gene_name": "MTPAP", "organism": "Bovine", "refseq_name": "poly(A) RNA polymerase, mitochondrial", "refseq_ac": "XP_002692192", "gene_names_uniprotkb": "MTPAP", "gene_names_refseq": "MTPAP", "protein_names_uniprotkb": "Mitochondrial poly(A) polymerase", "protein_names_refseq": "poly(A) RNA polymerase, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:511412)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0030145 manganese ion binding;GO:0042803 protein homodimerization activity;GO:0002134 UTP binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0000965 mitochondrial RNA 3'-end processing;GO:0097222 mitochondrial mRNA polyadenylation;GO:0071044 histone mRNA catabolic process;GO:0031123 RNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSM5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSN0-1", "uniprot_id": "F1MSN0_BOVIN", "mass": 24578.0, "length": 223, "protein_name": "Suppressor of cytokine signaling 1", "gene_name": "SOCS1", "organism": "Bovine", "refseq_name": "suppressor of cytokine signaling 1", "refseq_ac": "XP_002698010", "gene_names_uniprotkb": "SOCS1", "gene_names_refseq": "SOCS1", "protein_names_uniprotkb": "Suppressor of cytokine signaling 1", "protein_names_refseq": "suppressor of cytokine signaling 1", "tax_id": 9913, "disease": "", "pathway": " (bta:518795); (R-BTA-6785807); (R-BTA-877300); (R-BTA-877312); (R-BTA-909733); (R-BTA-9705462); (R-BTA-983168)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential negative regulator of type I and type II interferon (IFN) signaling, as well as that of other cytokines, including IL2, IL4, IL6 and leukemia inhibitory factor (LIF). Downregulates cytokine signaling by inhibiting the JAK/STAT signaling pathway. Acts by binding to JAK proteins and to IFNGR1 and inhibiting their kinase activity. In vitro, suppresses Tec protein-tyrosine activity. Regulates IFN-gamma (IFNG)-mediated sensory neuron survival. Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, 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0, "hit_score": 0.1, "record_id": "F1MSN0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSN2-1", "uniprot_id": "F1MSN2_BOVIN", "mass": 35441.0, "length": 319, "protein_name": "Tumor-associated calcium signal transducer 2", "gene_name": "TACSTD2", "organism": "Bovine", "refseq_name": "tumor-associated calcium signal transducer 2", "refseq_ac": "XP_002686409", "gene_names_uniprotkb": "TACSTD2", "gene_names_refseq": "TACSTD2", "protein_names_uniprotkb": "Tumor-associated calcium signal transducer 2", "protein_names_refseq": "tumor-associated calcium signal transducer 2", "tax_id": 9913, "disease": "", "pathway": " (bta:539853)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May function as a growth factor receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, 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"go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005886 plasma membrane", "go_biological_process": "GO:2000738 positive regulation of stem cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSN2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSR6-1", "uniprot_id": "F1MSR6_BOVIN", "mass": 91657.0, "length": 801, "protein_name": "Pre-rRNA-processing protein TSR1 homolog", "gene_name": "TSR1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TSR1", "gene_names_refseq": "", "protein_names_uniprotkb": "Pre-rRNA-processing protein TSR1 homolog", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-6791226)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required during maturation of the 40S ribosomal subunit in the nucleolus., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, 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"glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003924 GTPase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0030686 90S preribosome", "go_biological_process": "GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSR6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSS4-1", "uniprot_id": "F1MSS4_BOVIN", "mass": 40096.0, "length": 357, "protein_name": "Hexosyltransferase", "gene_name": "B3GNT4", "organism": "Bovine", "refseq_name": "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4", "refseq_ac": "XP_024833467", "gene_names_uniprotkb": "B3GNT4", "gene_names_refseq": "B3GNT4", "protein_names_uniprotkb": "Hexosyltransferase; 2.4.1.-", "protein_names_refseq": "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4", "tax_id": 9913, "disease": "", "pathway": " (bta:534619); (R-BTA-2022854); (R-BTA-913709)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AAA9RX40", "ec_number_list": "2.4.1.-", "go_molecular_function": "GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity;GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine;GO:0030311 poly-N-acetyllactosamine biosynthetic process", "synthesized_glycan_count": 1159, "hit_score": 0.1, "record_id": "F1MSS4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSV1-1", "uniprot_id": "F1MSV1_BOVIN", "mass": 81092.0, "length": 717, "protein_name": "Interleukin-31 receptor subunit alpha", "gene_name": "IL31RA", "organism": "Bovine", "refseq_name": "interleukin-31 receptor subunit alpha precursor", "refseq_ac": "NP_001179492", "gene_names_uniprotkb": "IL31RA", "gene_names_refseq": "IL31RA", "protein_names_uniprotkb": "Interleukin-31 receptor subunit alpha; GLM-R; Gp130-like monocyte receptor; ZcytoR17", "protein_names_refseq": "interleukin-31 receptor subunit alpha precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:522636)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019955 cytokine binding;GO:0004896 cytokine receptor activity", "go_cellular_component": "GO:0043235 receptor complex;GO:0009897 external side of plasma membrane;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0019221 cytokine-mediated signaling pathway;GO:0002376 immune system process;GO:0030224 monocyte differentiation;GO:0007259 cell surface receptor signaling pathway via JAK-STAT", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSV1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSV5-1", "uniprot_id": "F1MSV5_BOVIN", "mass": 60868.0, "length": 554, "protein_name": "glycerol kinase", "gene_name": "GK2", "organism": "Bovine", "refseq_name": "glycerol kinase 2", "refseq_ac": "NP_001243480", "gene_names_uniprotkb": "GK2", "gene_names_refseq": "GK2", "protein_names_uniprotkb": "glycerol kinase; 2.7.1.30", "protein_names_refseq": "glycerol kinase 2", "tax_id": 9913, "disease": "", "pathway": " (bta:540143); (R-BTA-75109)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.1.30", "go_molecular_function": "GO:0004370 glycerol kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0097226 sperm mitochondrial sheath;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0019563 glycerol catabolic process;GO:0046167 glycerol-3-phosphate biosynthetic process;GO:0006641 triglyceride metabolic process;GO:0006071 glycerol metabolic process;GO:0120317 sperm mitochondrial sheath assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSV5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSZ3-1", "uniprot_id": "F1MSZ3_BOVIN", "mass": 35013.0, "length": 310, "protein_name": "Olfactory receptor", "gene_name": "OR4P7", "organism": "Bovine", "refseq_name": "olfactory receptor 4P4", "refseq_ac": "NP_001376958", "gene_names_uniprotkb": "OR4P7", "gene_names_refseq": "OR4P7", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 4P4", "tax_id": 9913, "disease": "", "pathway": " (bta:521252)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSZ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSZ6-1", "uniprot_id": "F1MSZ6_BOVIN", "mass": 52440.0, "length": 465, "protein_name": "Antithrombin-III", "gene_name": "SERPINC1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SERPINC1", "gene_names_refseq": "", "protein_names_uniprotkb": "Antithrombin-III; Serpin C1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0002020 protease binding;GO:0004867 serine-type endopeptidase inhibitor activity;GO:0008201 heparin binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007596 blood coagulation;GO:0030193 regulation of blood coagulation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSZ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MT34-1", "uniprot_id": "F1MT34_BOVIN", "mass": 36713.0, "length": 324, "protein_name": "Vomeronasal type-1 receptor", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Vomeronasal type-1 receptor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005550 pheromone binding;GO:0016503 pheromone receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0019236 response to pheromone;GO:0007606 sensory perception of chemical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MT34-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MTB2-1", "uniprot_id": "F1MTB2_BOVIN", "mass": 36374.0, "length": 328, "protein_name": "P2Y purinoceptor 6", "gene_name": "P2RY6", "organism": "Bovine", "refseq_name": "P2Y purinoceptor 6", "refseq_ac": "NP_001179224", "gene_names_uniprotkb": "P2RY6", "gene_names_refseq": "P2RY6", "protein_names_uniprotkb": "P2Y purinoceptor 6", "protein_names_refseq": "P2Y purinoceptor 6; purinergic P2Y6 receptor; pyrimidinergic receptor P2Y, G-protein coupled, 6", "tax_id": 9913, "disease": "", "pathway": " (bta:539703); (R-BTA-416476); (R-BTA-417957)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AAA9TFP2", "ec_number_list": "", "go_molecular_function": "GO:0001621 G protein-coupled ADP receptor activity;GO:0045029 G protein-coupled UDP receptor activity;GO:0045030 G protein-coupled UTP receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0032962 positive regulation of inositol trisphosphate biosynthetic process;GO:0007186 G protein-coupled receptor signaling pathway;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation;GO:1905835 cellular response to pyrimidine ribonucleotide", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MTB2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MTC3-1", "uniprot_id": "F1MTC3_BOVIN", "mass": 92143.0, "length": 838, "protein_name": "Zinc fingers and homeoboxes protein 2", "gene_name": "ZHX2", "organism": "Bovine", "refseq_name": "zinc fingers and homeoboxes protein 2", "refseq_ac": "NP_001193335", "gene_names_uniprotkb": "ZHX2", "gene_names_refseq": "ZHX2", "protein_names_uniprotkb": "Zinc fingers and homeoboxes protein 2; Zinc finger and homeodomain protein 2", "protein_names_refseq": "zinc fingers and homeoboxes protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:515040)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells. In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0060040 retinal bipolar neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MTC3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MTC9-1", "uniprot_id": "F1MTC9_BOVIN", "mass": 38396.0, "length": 337, "protein_name": "Trace amine associated receptor 5", "gene_name": "TAAR5", "organism": "Bovine", "refseq_name": "trace amine-associated receptor 5", "refseq_ac": "XP_002690298", "gene_names_uniprotkb": "TAAR5", "gene_names_refseq": "TAAR5", "protein_names_uniprotkb": "Trace amine associated receptor 5", "protein_names_refseq": "trace amine-associated receptor 5", "tax_id": 9913, "disease": "", "pathway": " (bta:509368); (R-BTA-375280); (R-BTA-418555)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001594 trace-amine receptor activity;GO:1990081 trimethylamine receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0050890 cognition;GO:0007606 sensory perception of chemical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MTC9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MTF4-1", "uniprot_id": "F1MTF4_BOVIN", "mass": 27438.0, "length": 246, "protein_name": "Granzyme B", "gene_name": "LOC508646", "organism": "Bovine", "refseq_name": "granzyme B", "refseq_ac": "XP_002696692", "gene_names_uniprotkb": "LOC508646", "gene_names_refseq": "LOC508646", "protein_names_uniprotkb": "Granzyme B", "protein_names_refseq": "granzyme B", "tax_id": 9913, "disease": "", "pathway": " (bta:508646); (R-BTA-5620971); (R-BTA-75108)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, 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Required in the control of cell shape., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007010 cytoskeleton organization;GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MTQ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MTW5-1", "uniprot_id": "F1MTW5_BOVIN", "mass": 26294.0, "length": 248, "protein_name": "Mannose binding lectin 1", "gene_name": "MBL1", "organism": "Bovine", "refseq_name": "mannose-binding protein A isoform X1", "refseq_ac": "XP_059738436", "gene_names_uniprotkb": "MBL1", "gene_names_refseq": "MBL-A; MBL1; MBLA", "protein_names_uniprotkb": "Mannose binding lectin 1", "protein_names_refseq": "mannose-binding protein A isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005537 D-mannose binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005771 multivesicular body", "go_biological_process": "GO:0043129 surfactant homeostasis;GO:0050766 positive regulation of phagocytosis;GO:0001867 complement activation, lectin pathway;GO:0006958 complement activation, classical pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MTW5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MTW9-1", "uniprot_id": "F1MTW9_BOVIN", "mass": 56367.0, "length": 493, "protein_name": "E3 ubiquitin-protein ligase TRIM35", "gene_name": "TRIM35", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase TRIM35", "refseq_ac": "XP_002689839", "gene_names_uniprotkb": "TRIM35", "gene_names_refseq": "TRIM35", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM35; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM35", "tax_id": 9913, "disease": "", "pathway": " (bta:518310)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "E3 ubiquitin-protein ligase that participates in multiple biological processes including cell death, glucose metabolism, and in particular, the innate immune response. Mediates 'Lys-63'-linked polyubiquitination of TRAF3 thereby promoting type I interferon production via RIG-I signaling pathway. Can also catalyze 'Lys-48'-linked polyubiquitination and proteasomal degradation of viral proteins such as influenza virus PB2. Acts as a negative feedback regulator of TLR7- and TLR9-triggered signaling. Mechanistically, promotes the 'Lys-48'-linked ubiquitination of IRF7 and induces its degradation via a proteasome-dependent pathway. Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0044790 suppression of viral release by host;GO:0043065 positive regulation of apoptotic process;GO:0045087 innate immune response;GO:0006915 apoptotic process;GO:0045930 negative regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MTW9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MTZ3-1", "uniprot_id": "F1MTZ3_BOVIN", "mass": 72691.0, "length": 649, "protein_name": "Ubiquitin-associated and SH3 domain-containing protein B", "gene_name": "UBASH3B", "organism": "Bovine", "refseq_name": "ubiquitin-associated and SH3 domain-containing protein B", "refseq_ac": "NP_001193057", "gene_names_uniprotkb": "UBASH3B", "gene_names_refseq": "UBASH3B", "protein_names_uniprotkb": "Ubiquitin-associated and SH3 domain-containing protein B; 3.1.3.48; Cbl-interacting protein p70; Suppressor of T-cell receptor signaling 1; T-cell ubiquitin ligand 2; Tyrosine-protein phosphatase STS1/TULA2", "protein_names_refseq": "ubiquitin-associated and SH3 domain-containing protein B", "tax_id": 9913, "disease": "", "pathway": " (bta:523809)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.48;3.1.3.16;3.1.3.2;3.1.3.67;3.1.3.21;3.1.3.5;3.1.3.18", "go_molecular_function": "GO:0042802 identical protein binding;GO:0051219 phosphoprotein binding;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0070527 platelet aggregation;GO:0009968 negative regulation of signal transduction;GO:0051279 regulation of release of sequestered calcium ion into cytosol;GO:0045779 negative regulation of bone resorption;GO:0045670 regulation of osteoclast differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MTZ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MTZ7-1", "uniprot_id": "F1MTZ7_BOVIN", "mass": 33820.0, "length": 295, "protein_name": "Glycine N-acyltransferase-like protein", "gene_name": "LOC104974345", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC104974345", "gene_names_refseq": "", "protein_names_uniprotkb": "Glycine N-acyltransferase-like protein; 2.3.1.-", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.-;2.3.1.13;2.3.1.71", "go_molecular_function": "GO:0047962 glycine N-benzoyltransferase activity;GO:0047961 glycine N-acyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0009636 response to toxic substance", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MTZ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MTZ8-1", "uniprot_id": "F1MTZ8_BOVIN", "mass": 59013.0, "length": 543, "protein_name": "Tether containing UBX domain for GLUT4", "gene_name": "ASPSCR1", "organism": "Bovine", "refseq_name": "tether containing UBX domain for GLUT4 isoform X1", "refseq_ac": "XP_059734015", "gene_names_uniprotkb": "ASPSCR1", "gene_names_refseq": "ASPSCR1", "protein_names_uniprotkb": "Tether containing UBX domain for GLUT4", "protein_names_refseq": "tether containing UBX domain for GLUT4 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0042593 glucose homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MTZ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSG2-1", "uniprot_id": "F1MSG2_BOVIN", "mass": 117672.0, "length": 1045, "protein_name": "F-box DNA helicase 1", "gene_name": "FBH1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FBH1", "gene_names_refseq": "", "protein_names_uniprotkb": "F-box DNA helicase 1; 5.6.2.4; DNA 3'-5' helicase 1; F-box only protein 18", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0043138 3'-5' DNA helicase activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006281 DNA repair;GO:0031297 replication fork processing;GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:0072429 response to intra-S DNA damage checkpoint signaling;GO:0000724 double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSG2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MQX0-1", "uniprot_id": "F1MQX0_BOVIN", "mass": 74294.0, "length": 675, "protein_name": "Acetyl-coenzyme A synthetase", "gene_name": "ACSS1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ACSS1", "gene_names_refseq": "", "protein_names_uniprotkb": "Acetyl-coenzyme A synthetase; 6.2.1.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.2.1.1;6.2.1.17", "go_molecular_function": "GO:0005524 ATP binding;GO:0003987 acetate-CoA ligase activity;GO:0050218 propionate-CoA ligase activity;GO:0016208 AMP binding", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0019427 acetyl-CoA biosynthetic process from acetate", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MQX0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MMT2-1", "uniprot_id": "F1MMT2_BOVIN", "mass": 343597.0, "length": 3122, "protein_name": "Laminin subunit alpha-2", "gene_name": "LAMA2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LAMA2", "gene_names_refseq": "", "protein_names_uniprotkb": "Laminin subunit alpha-2; Laminin M chain; Laminin-12 subunit alpha; Laminin-2 subunit alpha; Laminin-4 subunit alpha; Merosin heavy chain", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, 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"reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.19.12", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZ13-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MYV7-1", "uniprot_id": "F1MYV7_BOVIN", "mass": 61512.0, "length": 564, "protein_name": "DDB1- and CUL4-associated factor 10", "gene_name": "DCAF10", "organism": "Bovine", "refseq_name": "DDB1- and CUL4-associated factor 10 isoform X1", "refseq_ac": "XP_002689774", "gene_names_uniprotkb": "DCAF10", "gene_names_refseq": "DCAF10", "protein_names_uniprotkb": "DDB1- and CUL4-associated factor 10; WD repeat-containing protein 32", "protein_names_refseq": "DDB1- and CUL4-associated factor 10 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:509776); (R-BTA-8951664)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0080008 Cul4-RING E3 ubiquitin ligase complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MYV7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUJ4-1", "uniprot_id": "F1MUJ4_BOVIN", "mass": 80027.0, "length": 720, "protein_name": "Inactive serine protease PAMR1", "gene_name": "PAMR1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PAMR1", "gene_names_refseq": "", "protein_names_uniprotkb": "Inactive serine protease PAMR1; Peptidase domain-containing protein associated with muscle regeneration 1; Regeneration-associated muscle protease homolog", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in regeneration of skeletal muscle., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUJ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MW72-1", "uniprot_id": "F1MW72_BOVIN", "mass": 87427.0, "length": 759, "protein_name": "Transmembrane channel-like protein", "gene_name": "TMC1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TMC1", "gene_names_refseq": "", "protein_names_uniprotkb": "Transmembrane channel-like protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008381 mechanosensitive monoatomic ion channel activity;GO:0005245 voltage-gated calcium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane;GO:0032426 stereocilium tip", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MW72-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MX69-1", "uniprot_id": "F1MX69_BOVIN", "mass": 30070.0, "length": 259, "protein_name": "Phosphoglycerate mutase", "gene_name": "BPGM", "organism": "Bovine", "refseq_name": "bisphosphoglycerate mutase", "refseq_ac": "XP_024849352", "gene_names_uniprotkb": "BPGM", "gene_names_refseq": "LOC112447087", "protein_names_uniprotkb": "Phosphoglycerate mutase; 5.4.2.11; 5.4.2.4", "protein_names_refseq": "bisphosphoglycerate mutase", "tax_id": 9913, "disease": "", "pathway": " (bta:112447087); (R-BTA-70171)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.4.2.11;5.4.2.4", "go_molecular_function": "GO:0004082 bisphosphoglycerate mutase activity;GO:0004619 phosphoglycerate mutase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MX69-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MW49-1", "uniprot_id": "F1MW49_BOVIN", "mass": 27040.0, "length": 238, "protein_name": "Dolichyldiphosphatase", "gene_name": "DOLPP1", "organism": "Bovine", "refseq_name": "dolichyldiphosphatase 1", "refseq_ac": "NP_001178970", "gene_names_uniprotkb": "DOLPP1", "gene_names_refseq": "DOLPP1", "protein_names_uniprotkb": "Dolichyldiphosphatase; 3.6.1.43", "protein_names_refseq": "dolichyl pyrophosphate phosphatase 1; dolichyldiphosphatase 1", "tax_id": 9913, "disease": "", "pathway": " (bta:504908); (R-BTA-446199)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.1.43", "go_molecular_function": "GO:0047874 dolichyldiphosphatase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MW49-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZJ4-1", "uniprot_id": "F1MZJ4_BOVIN", "mass": 82828.0, "length": 729, "protein_name": "Rho-related BTB domain-containing protein 2", "gene_name": "RHOBTB2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RHOBTB2", "gene_names_refseq": "", "protein_names_uniprotkb": "Rho-related BTB domain-containing protein 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-9013418)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulator of cell proliferation and apoptosis. It likely functions as a substrate-adapter that recruits key substrates, e.g. MSI2, to CUL3-based ubiquitin ligase complexes for degradation. Required for MSI2 ubiquitination and degradation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0010008 endosome membrane;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle;GO:0042995 cell projection", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction;GO:0007015 actin filament organization;GO:0007165 signal transduction;GO:0032956 regulation of actin cytoskeleton organization;GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZJ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUM9-1", "uniprot_id": "F1MUM9_BOVIN", "mass": 130452.0, "length": 1175, "protein_name": "Double-stranded RNA-specific adenosine deaminase", "gene_name": "ADAR", "organism": "Bovine", "refseq_name": "double-stranded RNA-specific adenosine deaminase isoform X6", "refseq_ac": "XP_059740955", "gene_names_uniprotkb": "ADAR", "gene_names_refseq": "ADAR", "protein_names_uniprotkb": "Double-stranded RNA-specific adenosine deaminase; 3.5.4.37", "protein_names_refseq": "double-stranded RNA-specific adenosine deaminase isoform X6", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-75102); (R-BTA-77042); (R-BTA-9833482)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.4.37", "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0004000 adenosine deaminase activity;GO:0046872 metal ion binding;GO:0003726 double-stranded RNA adenosine deaminase activity", "go_cellular_component": "GO:0031981 nuclear lumen;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0044530 supraspliceosomal complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0031047 regulatory ncRNA-mediated gene silencing;GO:0016556 mRNA modification", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUM9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MU22-1", "uniprot_id": "F1MU22_BOVIN", "mass": 61468.0, "length": 553, "protein_name": "Carboxylic ester hydrolase", "gene_name": "CES2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CES2", "gene_names_refseq": "", "protein_names_uniprotkb": "Carboxylic ester hydrolase; 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This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Plays an important role in normal erythropoiesis. It has a role in the differentiation of erythroid progenitors. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity. Mediates docking of ADAM10 to zonula adherens by interacting with ADAM10 and, in a PDZD11-dependent manner, with the zonula adherens protein PLEKHA7., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, 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"synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MWN0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MYY5-1", "uniprot_id": "F1MYY5_BOVIN", "mass": 60541.0, "length": 508, "protein_name": "Trichoplein keratin filament-binding protein", "gene_name": "TCHP", "organism": "Bovine", "refseq_name": "trichoplein keratin filament-binding protein isoform X2", "refseq_ac": "XP_059732009", "gene_names_uniprotkb": "TCHP", "gene_names_refseq": "TCHP", "protein_names_uniprotkb": "Trichoplein keratin filament-binding protein", "protein_names_refseq": "trichoplein keratin filament-binding protein isoform X2", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, 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axoneme;GO:0045095 keratin filament", "go_biological_process": "GO:0030030 cell projection organization;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MYY5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZL1-1", "uniprot_id": "F1MZL1_BOVIN", "mass": 60737.0, "length": 575, "protein_name": "Muellerian-inhibiting factor", "gene_name": "AMH", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AMH", "gene_names_refseq": "", "protein_names_uniprotkb": "Muellerian-inhibiting factor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-201451)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The anti-Muellerian hormone (AMH) plays an important role in several reproductive functions. Anti-Muellerian hormone binds and activates AMHR2, its specific type-II receptor, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A) to regulate target gene expression through downstream SMAD protein signal transduction. Produced and secreted by Sertoli cells of the male fetus, anti-Muellerian hormone induces Muellerian duct regression during male fetal sexual differentiation. In female, it is produced by granulosa cells of the preantral and small antral follicles and acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles. Also plays a role in Leydig cell differentiation and function., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005160 transforming growth factor beta receptor binding;GO:0008083 growth factor activity;GO:0005114 type II transforming growth factor beta receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0030154 cell differentiation;GO:0001655 urogenital system development;GO:0001880 Mullerian duct regression;GO:0007506 gonadal mesoderm development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZL1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXR5-1", "uniprot_id": "F1MXR5_BOVIN", "mass": 55184.0, "length": 500, "protein_name": "Interferon gamma receptor 1", "gene_name": "IFNGR1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IFNGR1", "gene_names_refseq": "", "protein_names_uniprotkb": "Interferon gamma receptor 1; 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ST3GAL3", "protein_names_uniprotkb": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase; 2.4.3.6; Beta-galactoside alpha-2,3-sialyltransferase 3; Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase; N-acetyllactosaminide alpha-2,3-sialyltransferase; ST3Gal III; ST3N; Sialyltransferase 6", "protein_names_refseq": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X8", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2022854); (R-BTA-4085001); (R-BTA-9037629); (R-BTA-977068); (R-BTA-9840309)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.3.9;2.4.3.2;2.4.3.4;2.4.3.6", "go_molecular_function": "GO:0008373 sialyltransferase activity;GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity;GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0001574 ganglioside biosynthetic process", "synthesized_glycan_count": 2417, "hit_score": 0.1, "record_id": "F1MZD3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MYX6-1", "uniprot_id": "F1MYX6_BOVIN", "mass": 57694.0, "length": 528, "protein_name": "Large neutral amino acids transporter small subunit 2", "gene_name": "SLC7A8", "organism": "Bovine", "refseq_name": "large neutral amino acids transporter small subunit 2", "refseq_ac": "NP_001179818", "gene_names_uniprotkb": "SLC7A8", "gene_names_refseq": "SLC7A8", "protein_names_uniprotkb": "Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; Solute carrier family 7 member 8", "protein_names_refseq": "glycoprotein-associated amino acid transporter LAT2; large neutral amino acids transporter small subunit 2; solute carrier family 7 (amino acid transporter, L-type), member 8; solute carrier family 7 (cationic amino acid transporter, y+ system), member 8", "tax_id": 9913, "disease": "", "pathway": " (bta:536818); (R-BTA-352230)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015180 L-alanine transmembrane transporter activity;GO:0015187 glycine transmembrane transporter activity;GO:0046982 protein heterodimerization activity;GO:0019534 toxin transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0031528 microvillus membrane", "go_biological_process": "GO:0035524 proline transmembrane transport;GO:1903801 L-leucine import across plasma membrane;GO:0015827 tryptophan transport;GO:0015829 valine transport;GO:1904273 L-alanine import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MYX6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZP7-1", "uniprot_id": "F1MZP7_BOVIN", "mass": 124372.0, "length": 1151, "protein_name": "Myelin regulatory factor", "gene_name": "MYRF", "organism": "Bovine", "refseq_name": "myelin regulatory factor isoform X2", "refseq_ac": "XP_024843233", "gene_names_uniprotkb": "MYRF", "gene_names_refseq": "MYRF", "protein_names_uniprotkb": "Myelin regulatory factor; Myelin gene regulatory factor", "protein_names_refseq": "myelin regulatory factor isoform X2", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Constitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG, DUSP15 and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifically recognizes and binds DNA sequence 5'-CTGGYAC-3' in the regulatory regions of myelin-specific genes and directly activates their expression. Not only required during oligodendrocyte differentiation but is also required on an ongoing basis for the maintenance of expression of myelin genes and for the maintenance of a mature, viable oligodendrocyte phenotype., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008233 peptidase activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0016540 protein autoprocessing;GO:0045893 positive regulation of DNA-templated transcription;GO:0031643 positive regulation of myelination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZP7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MX61-1", "uniprot_id": "F1MX61_BOVIN", "mass": 145857.0, "length": 1304, "protein_name": "Splicing factor 3B subunit 1", "gene_name": "SF3B1", "organism": "Bovine", "refseq_name": "splicing factor 3B subunit 1", "refseq_ac": "NP_001179923", "gene_names_uniprotkb": "SF3B1", "gene_names_refseq": "SF3B1", "protein_names_uniprotkb": "Splicing factor 3B subunit 1; Pre-mRNA-splicing factor SF3b 155 kDa subunit; Spliceosome-associated protein 155", "protein_names_refseq": "splicing factor 3B subunit 1; splicing factor 3b, subunit 1, 155kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:510177); (R-BTA-5250924); (R-BTA-72163); (R-BTA-72165); (R-BTA-9770562); (R-BTA-9943411)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0036002 pre-mRNA binding;GO:1990935 splicing factor binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0000785 chromatin;GO:0071013 catalytic step 2 spliceosome;GO:0005686 U2 snRNP;GO:0034693 U11/U12 snRNP", "go_biological_process": "GO:0000245 spliceosomal complex assembly;GO:0045945 positive regulation of transcription by RNA polymerase III", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MX61-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWZ4-1", "uniprot_id": "F1MWZ4_BOVIN", "mass": 75273.0, "length": 676, "protein_name": "RNA helicase", "gene_name": "DHX33", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DHX33", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA helicase; 3.6.4.13", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Implicated in nucleolar organization, ribosome biogenesis, protein synthesis and cytoplasmic dsRNA sensing. Stimulates RNA polymerase I transcription of the 47S precursor rRNA. Associates with ribosomal DNA (rDNA) loci where it is involved in POLR1A recruitment. In the cytoplasm, promotes elongation-competent 80S ribosome assembly at the late stage of mRNA translation initiation. Senses cytosolic dsRNA mediating NLRP3 inflammasome formation in macrophages and type I interferon production in myeloid dendritic cells. Required for NLRP3 activation induced by viral dsRNA and bacterial RNA. In dendritic cells, required for induction of type I interferon production induced by cytoplasmic dsRNA via the activation of MAPK and NF-kappa-B signaling pathways., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0003724 RNA helicase activity;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005654 nucleoplasm;GO:0072559 NLRP3 inflammasome complex", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade;GO:0006413 translational initiation;GO:0045943 positive regulation of transcription by RNA polymerase I;GO:0032481 positive regulation of type I interferon production;GO:1900227 positive regulation of NLRP3 inflammasome complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MWZ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MX70-1", "uniprot_id": "F1MX70_BOVIN", "mass": 76336.0, "length": 660, "protein_name": "Anoctamin", "gene_name": "ANO10", "organism": "Bovine", "refseq_name": "anoctamin-10 isoform X1", "refseq_ac": "XP_024838615", "gene_names_uniprotkb": "ANO10", "gene_names_refseq": "ANO10; TMEM16K", "protein_names_uniprotkb": "Anoctamin", "protein_names_refseq": "anoctamin-10 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2672351)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005227 calcium-activated cation channel activity", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:1902476 chloride transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MX70-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUZ6-1", "uniprot_id": "F1MUZ6_BOVIN", "mass": 73010.0, "length": 667, "protein_name": "Ankyrin repeat and LEM domain containing 1", "gene_name": "ANKLE1", "organism": "Bovine", "refseq_name": "ankyrin repeat and LEM domain-containing protein 1", "refseq_ac": "XP_005208615", "gene_names_uniprotkb": "ANKLE1", "gene_names_refseq": "ANKLE1", "protein_names_uniprotkb": "Ankyrin repeat and LEM domain containing 1", "protein_names_refseq": "ankyrin repeat and LEM domain-containing protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:537502)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0030145 manganese ion binding;GO:0004520 DNA endonuclease activity;GO:0050897 cobalt ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0030496 midbody;GO:0005737 cytoplasm", "go_biological_process": "GO:0006974 DNA damage response;GO:0006611 protein export from nucleus;GO:0000712 resolution of meiotic recombination intermediates;GO:0000724 double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUZ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MU59-1", "uniprot_id": "F1MU59_BOVIN", "mass": 35409.0, "length": 321, "protein_name": "Phospholipid phosphatase-related protein type 5", "gene_name": "PLPPR5", "organism": "Bovine", "refseq_name": "phospholipid phosphatase-related protein type 5 isoform X2", "refseq_ac": "XP_005204304", "gene_names_uniprotkb": "PLPPR5", "gene_names_refseq": "PLPPR5", "protein_names_uniprotkb": "Phospholipid phosphatase-related protein type 5; Lipid phosphate phosphatase-related protein type 5; Plasticity-related gene 5 protein", "protein_names_refseq": "phospholipid phosphatase-related protein type 5 isoform X2", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-419408)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory-mediated axonal retraction., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008195 phosphatidate phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006644 phospholipid metabolic process;GO:0007165 signal transduction;GO:0046839 phospholipid dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MU59-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MW83-1", "uniprot_id": "F1MW83_BOVIN", "mass": 63988.0, "length": 602, "protein_name": "Forkhead box K2", "gene_name": "FOXK2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FOXK2", "gene_names_refseq": "", "protein_names_uniprotkb": "Forkhead box K2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:532359); 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Negative regulatory element-binding protein", "protein_names_refseq": "SON DNA binding protein; protein SON isoform 2", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0016607 nuclear speck", "go_biological_process": "GO:0043484 regulation of RNA splicing;GO:0051726 regulation of cell cycle;GO:0048024 regulation of mRNA splicing, via spliceosome;GO:0006397 mRNA processing;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MYN8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MYC3-1", "uniprot_id": "F1MYC3_BOVIN", "mass": 92738.0, "length": 835, "protein_name": "Amyloid beta protein binding family A member 1", "gene_name": "APBA1", "organism": "Bovine", "refseq_name": "amyloid-beta A4 precursor protein-binding family A member 1", "refseq_ac": "NP_001192743", "gene_names_uniprotkb": "APBA1", "gene_names_refseq": "APBA1", "protein_names_uniprotkb": "Amyloid beta protein binding family A member 1", "protein_names_refseq": "amyloid beta (A4) precursor protein-binding, family A, member 1 (X11); amyloid-beta A4 precursor protein-binding family A member 1", "tax_id": 9913, "disease": "", "pathway": " (bta:515571)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0048787 presynaptic active zone membrane;GO:0005794 Golgi apparatus;GO:0098685 Schaffer collateral - CA1 synapse", "go_biological_process": "GO:0099171 presynaptic modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MYC3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MX50-1", "uniprot_id": "F1MX50_BOVIN", "mass": 23959.0, "length": 221, "protein_name": "Cellular repressor of E1A stimulateds 1", "gene_name": "CREG1", "organism": "Bovine", "refseq_name": "protein CREG1 isoform X1", "refseq_ac": "XP_024845191", "gene_names_uniprotkb": "CREG1", "gene_names_refseq": "CREG1", "protein_names_uniprotkb": "Cellular repressor of E1A stimulateds 1", "protein_names_refseq": "protein CREG1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-6798695)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005159 insulin-like growth factor receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005615 extracellular space;GO:0005768 endosome;GO:0005764 lysosome;GO:0005667 transcription regulator complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MX50-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MYG2-1", "uniprot_id": "F1MYG2_BOVIN", "mass": 86664.0, "length": 766, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "TLK1", "organism": "Bovine", "refseq_name": "serine/threonine-protein kinase tousled-like 1 isoform X1", "refseq_ac": "XP_002685327", "gene_names_uniprotkb": "TLK1", "gene_names_refseq": "TLK1", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase tousled-like 1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:537517)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0007059 chromosome segregation;GO:0035556 intracellular signal transduction;GO:1902275 regulation of chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MYG2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZS3-1", "uniprot_id": "F1MZS3_BOVIN", "mass": 56359.0, "length": 490, "protein_name": "[histone H3]-lysine(4) N-trimethyltransferase", "gene_name": "SMYD1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SMYD1", "gene_names_refseq": "", "protein_names_uniprotkb": "[histone H3]-lysine(4) N-trimethyltransferase; 2.1.1.354; SET and MYND domain-containing protein 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.359;2.1.1.355;2.1.1.354;2.1.1.362;2.1.1.361;2.1.1.-", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0042800 histone H3K4 methyltransferase activity;GO:0140999 histone H3K4 trimethyltransferase activity;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0045892 negative regulation of DNA-templated transcription;GO:0032259 methylation;GO:0010831 positive regulation of myotube differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZS3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MYS1-1", "uniprot_id": "F1MYS1_BOVIN", "mass": 54991.0, "length": 478, "protein_name": "Sphingomyelin synthase-related protein 1", "gene_name": "SAMD8", "organism": "Bovine", "refseq_name": "sphingomyelin synthase-related protein 1 isoform X1", "refseq_ac": "XP_002698962", "gene_names_uniprotkb": "SAMD8", "gene_names_refseq": "SAMD8", "protein_names_uniprotkb": "Sphingomyelin synthase-related protein 1; 3.1.4.62; Ceramide phosphoethanolamine synthase; Phosphatidylethanolamine Phospholipase C; Sterile alpha motif domain-containing protein 8", "protein_names_refseq": "sphingomyelin synthase-related protein 1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:540644); (R-BTA-1660661)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Has phospholipase C (PLC) activity. Shows specificity for phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE), hydrolyzing PE to produce phosphoethanolamine and diacylglycerol (1,2-diacyl-sn-glycerol, DAG). This reaction might act as a regulatory switch to activate serine palmitoyltransferase (SPT) and promote sphingolipid metabolism. Can also function as a ceramide phosphoethanolamine (N-acylsphingoid 1-phosphoethanolamine, CPE) synthase when intracellular ceramide levels are elevated. Binds the headgroup from PE, which is smaller and more hydrophilic than the phosphocholine headgroup transferred in the canonical sphingomyelin synthesis (SMS) reaction by SMS1 or SMS2, and transfers it on to the primary hydroxyl of a ceramide in the lumen of the endoplasmic reticulum. Plays a role as a ceramide sensor, helping to regulate ceramide homeostasis in the endoplasmic reticulum, which is critical for maintaining the integrity of the early secretory pathway., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.8.27;3.1.4.62", "go_molecular_function": "GO:0016780 phosphotransferase activity, for other substituted phosphate groups;GO:0033188 sphingomyelin synthase activity;GO:0047493 ceramide cholinephosphotransferase activity", "go_cellular_component": "GO:0016020 membrane;GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0046513 ceramide biosynthetic process;GO:2000303 regulation of ceramide biosynthetic process;GO:0006665 sphingolipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MYS1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWG3-1", "uniprot_id": "F1MWG3_BOVIN", "mass": 104256.0, "length": 900, "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "CWC22", "organism": "Bovine", "refseq_name": "pre-mRNA-splicing factor CWC22 homolog", "refseq_ac": "XP_002685317", "gene_names_uniprotkb": "CWC22", "gene_names_refseq": "CWC22", "protein_names_uniprotkb": "Pre-mRNA-splicing factor CWC22 homolog; Nucampholin homolog", "protein_names_refseq": "pre-mRNA-splicing factor CWC22 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:781016); (R-BTA-72163)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for pre-mRNA splicing as component of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. Promotes exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0071006 U2-type catalytic step 1 spliceosome;GO:0071007 U2-type catalytic step 2 spliceosome;GO:0071005 U2-type precatalytic spliceosome;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MWG3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWN8-1", "uniprot_id": "F1MWN8_BOVIN", "mass": 103738.0, "length": 873, "protein_name": "Cilia and flagella associated protein 58", "gene_name": "CFAP58", "organism": "Bovine", "refseq_name": "cilia- and flagella-associated protein 58", "refseq_ac": "XP_002698546", "gene_names_uniprotkb": "CFAP58", "gene_names_refseq": "CFAP58", "protein_names_uniprotkb": "Cilia and flagella associated protein 58", "protein_names_refseq": "cilia- and flagella-associated protein 58", "tax_id": 9913, "disease": "", "pathway": " (bta:536914)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "39743588", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0097228 sperm principal piece;GO:0097225 sperm midpiece", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0007288 sperm axoneme assembly;GO:0120229 protein localization to motile cilium;GO:0120317 sperm mitochondrial sheath assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MWN8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MU62-1", "uniprot_id": "F1MU62_BOVIN", "mass": 58072.0, "length": 530, "protein_name": "Cleavage and polyadenylation specificity factor subunit 7", "gene_name": "CPSF7", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CPSF7", "gene_names_refseq": "", "protein_names_uniprotkb": "Cleavage and polyadenylation specificity factor subunit 7", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-73856); (R-BTA-77595); (R-BTA-9013422); (R-BTA-9770562)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs. CPSF7 activates directly the mRNA 3'-processing machinery. Binds to pA signals in RNA substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005847 mRNA cleavage and polyadenylation specificity factor complex", "go_biological_process": "GO:0051290 protein heterotetramerization;GO:0110104 mRNA alternative polyadenylation;GO:0180010 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MU62-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MX74-1", "uniprot_id": "F1MX74_BOVIN", "mass": 36213.0, "length": 311, "protein_name": "Progestin and adipoQ receptor family member 3", "gene_name": "PAQR3", "organism": "Bovine", "refseq_name": "progestin and adipoQ receptor family member 3", "refseq_ac": "NP_001421753", "gene_names_uniprotkb": "PAQR3", "gene_names_refseq": "PAQR3", "protein_names_uniprotkb": "Progestin and adipoQ receptor family member 3", "protein_names_refseq": "progestin and adipoQ receptor family member 3", "tax_id": 9913, "disease": "", "pathway": " (bta:534876); (R-BTA-5675221)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0043495 protein-membrane adaptor activity;GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0016020 membrane;GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0045542 positive regulation of cholesterol biosynthetic process;GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0034067 protein localization to Golgi apparatus;GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway;GO:2000640 positive regulation of SREBP signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MX74-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MVE6-1", "uniprot_id": "F1MVE6_BOVIN", "mass": 40789.0, "length": 361, "protein_name": "GH18 domain-containing protein", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "GH18 domain-containing protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004568 chitinase activity;GO:0008061 chitin binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0006032 chitin catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MVE6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZS1-1", "uniprot_id": "F1MZS1_BOVIN", "mass": 132319.0, "length": 1194, "protein_name": "WW and C2 domain containing 2", "gene_name": "WWC2", "organism": "Bovine", "refseq_name": "protein WWC2", "refseq_ac": "XP_024842231", "gene_names_uniprotkb": "WWC2", "gene_names_refseq": "WWC2", "protein_names_uniprotkb": "WW and C2 domain containing 2", "protein_names_refseq": "protein WWC2", "tax_id": 9913, "disease": "", "pathway": " (bta:532571)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0019900 kinase binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0046621 negative regulation of organ growth;GO:0035330 regulation of hippo signaling;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZS1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MYY8-1", "uniprot_id": "F1MYY8_BOVIN", "mass": 61405.0, "length": 539, "protein_name": "General transcription factor 3C polypeptide 5", "gene_name": "GTF3C5", "organism": "Bovine", "refseq_name": "general transcription factor 3C polypeptide 5 isoform X2", "refseq_ac": "XP_005213473", "gene_names_uniprotkb": "GTF3C5", "gene_names_refseq": "GTF3C5", "protein_names_uniprotkb": "General transcription factor 3C polypeptide 5; TF3C-epsilon; Transcription factor IIIC 63 kDa subunit; Transcription factor IIIC subunit epsilon", "protein_names_refseq": "general transcription factor 3C polypeptide 5 isoform X2", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-76061); (R-BTA-76066)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0000995 RNA polymerase III general transcription initiation factor activity", "go_cellular_component": "GO:0000127 transcription factor TFIIIC complex;GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0042791 5S class rRNA transcription by RNA polymerase III;GO:0006384 transcription initiation at RNA polymerase III promoter", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MYY8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZD0-1", "uniprot_id": "F1MZD0_BOVIN", "mass": 304139.0, "length": 2859, "protein_name": "Fibrillin 3", "gene_name": "FBN3", "organism": "Bovine", "refseq_name": "fibrillin-3", "refseq_ac": "XP_059744590", "gene_names_uniprotkb": "FBN3", "gene_names_refseq": "FBN3", "protein_names_uniprotkb": "Fibrillin 3", "protein_names_refseq": "fibrillin-3", "tax_id": 9913, "disease": "", "pathway": " (bta:787458)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hormone that targets the liver to increase plasma glucose levels. Secreted by white adipose tissue and circulates in the plasma. Acts in response to fasting and promotes blood glucose elevation by binding to the surface of hepatocytes. Promotes hepatocyte glucose release by activating the protein kinase A activity in the liver, resulting in rapid glucose release into the circulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0001527 microfibril", "go_biological_process": "GO:0048731 system development;GO:0009887 animal organ morphogenesis;GO:0048598 embryonic morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZD0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWE1-1", "uniprot_id": "F1MWE1_BOVIN", "mass": 62781.0, "length": 582, "protein_name": "Zinc finger protein 704", "gene_name": "ZNF704", "organism": "Bovine", "refseq_name": "zinc finger protein 704 isoform X1", "refseq_ac": "XP_024857284", "gene_names_uniprotkb": "ZNF704", "gene_names_refseq": "ZNF704", "protein_names_uniprotkb": "Zinc finger protein 704", "protein_names_refseq": "zinc finger protein 704 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-212436)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MWE1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MY06-1", "uniprot_id": "F1MY06_BOVIN", "mass": 193921.0, "length": 1836, "protein_name": "Trinucleotide repeat containing adaptor 6B", "gene_name": "TNRC6B", "organism": "Bovine", "refseq_name": "trinucleotide repeat-containing gene 6B protein", "refseq_ac": "NP_001179584", "gene_names_uniprotkb": "TNRC6B", "gene_names_refseq": "TNRC6B", "protein_names_uniprotkb": "Trinucleotide repeat containing adaptor 6B", "protein_names_refseq": "trinucleotide repeat containing 6B; 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0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0006355 regulation of DNA-templated transcription;GO:0048468 cell development;GO:0060059 embryonic retina morphogenesis in camera-type eye", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MW85-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZT2-1", "uniprot_id": "F1MZT2_BOVIN", "mass": 83680.0, "length": 693, "protein_name": "Crooked neck-like protein 1", "gene_name": "CRNKL1", "organism": "Bovine", "refseq_name": "crooked neck-like protein 1", "refseq_ac": "NP_001193451", "gene_names_uniprotkb": "CRNKL1", "gene_names_refseq": "CRNKL1", "protein_names_uniprotkb": "Crooked neck-like protein 1; Crooked neck homolog", "protein_names_refseq": "crooked neck pre-mRNA splicing factor-like 1; crooked neck-like protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:526536); (R-BTA-72163)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in pre-mRNA splicing process. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0071014 post-mRNA release spliceosomal complex;GO:0071007 U2-type catalytic step 2 spliceosome;GO:0000974 Prp19 complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000245 spliceosomal complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZT2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZB6-1", "uniprot_id": "F1MZB6_BOVIN", "mass": 48661.0, "length": 461, "protein_name": "Forkhead box A2", "gene_name": "FOXA2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FOXA2", "gene_names_refseq": "", "protein_names_uniprotkb": "Forkhead box A2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0019904 protein domain specific binding;GO:0043565 sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0031018 endocrine pancreas development;GO:0030193 regulation of blood coagulation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZB6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZJ2-1", "uniprot_id": "F1MZJ2_BOVIN", "mass": 27273.0, "length": 234, "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "OTUB2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "OTUB2", "gene_names_refseq": "", "protein_names_uniprotkb": "ubiquitinyl hydrolase 1; 3.4.19.12", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5689896)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.27;3.4.19.12;3.6.5.2;2.3.2.24;2.3.2.23", "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:0043130 ubiquitin binding", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0070536 protein K63-linked deubiquitination;GO:0071108 protein K48-linked deubiquitination;GO:0035871 protein K11-linked deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZJ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZB7-1", "uniprot_id": "F1MZB7_BOVIN", "mass": 94520.0, "length": 870, "protein_name": "Zinc finger and BTB domain containing 10", "gene_name": "ZBTB10", "organism": "Bovine", "refseq_name": "zinc finger and BTB domain-containing protein 10", "refseq_ac": "XP_002692786", "gene_names_uniprotkb": "ZBTB10", "gene_names_refseq": "ZBTB10", "protein_names_uniprotkb": "Zinc finger and BTB domain containing 10", "protein_names_refseq": "zinc finger and BTB domain-containing protein 10", "tax_id": 9913, "disease": "", "pathway": " (bta:785123)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042162 telomeric DNA binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZB7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MYU7-1", "uniprot_id": "F1MYU7_BOVIN", "mass": 63964.0, "length": 581, "protein_name": "Solute carrier family 15 member 3", "gene_name": "SLC15A3", "organism": "Bovine", "refseq_name": "solute carrier family 15 member 3", "refseq_ac": "XP_002699284", "gene_names_uniprotkb": "SLC15A3", "gene_names_refseq": "SLC15A3", "protein_names_uniprotkb": "Solute carrier family 15 member 3; Peptide transporter 3; Peptide/histidine transporter 2", "protein_names_refseq": "solute carrier family 15 member 3", "tax_id": 9913, "disease": "", "pathway": " (bta:513984); (R-BTA-427975)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Proton-coupled amino-acid transporter that transports free histidine and certain di- and tripeptides, and is involved in innate immune response. Preferably binds to short peptides with a basic residue at the first position and a hydrophobic residue at the second position. Also able to transport carnosine. Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015293 symporter activity;GO:0071916 dipeptide transmembrane transporter activity;GO:0015647 peptidoglycan transmembrane transporter activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0010008 endosome membrane;GO:0016020 membrane", "go_biological_process": "GO:0015031 protein transport;GO:0045087 innate immune response;GO:0006857 oligopeptide transport;GO:0140206 dipeptide import across plasma membrane;GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MYU7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZM6-1", "uniprot_id": "F1MZM6_BOVIN", "mass": 65694.0, "length": 591, "protein_name": "Ferric reductase 1", "gene_name": "FRRS1", "organism": "Bovine", "refseq_name": "ferric-chelate reductase 1 isoform X2", "refseq_ac": "XP_059740431", "gene_names_uniprotkb": "FRRS1", "gene_names_refseq": "FRRS1", "protein_names_uniprotkb": "Ferric reductase 1", "protein_names_refseq": "ferric-chelate reductase 1 isoform X2", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ferric reductase that reduces Fe(3+) to Fe(2+) and could play a role in iron import into cells. The electron donor and therefore the reaction mechanism are not known., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016722 oxidoreductase activity, acting on metal ions", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZM6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXH5-1", "uniprot_id": "F1MXH5_BOVIN", "mass": 71950.0, "length": 640, "protein_name": "Leucine rich repeat containing 4C", "gene_name": "LRRC4C", "organism": "Bovine", "refseq_name": "leucine-rich repeat-containing protein 4C", "refseq_ac": "XP_002693573", "gene_names_uniprotkb": "LRRC4C", "gene_names_refseq": "LRRC4C", "protein_names_uniprotkb": "Leucine rich repeat containing 4C", "protein_names_refseq": "leucine-rich repeat-containing protein 4C", "tax_id": 9913, "disease": "", "pathway": " (bta:528664)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0098632 cell-cell adhesion mediator activity", "go_cellular_component": "GO:0097060 synaptic membrane;GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0098839 postsynaptic density membrane;GO:0098685 Schaffer collateral - CA1 synapse", "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0050804 modulation of chemical synaptic transmission;GO:0099560 synaptic membrane adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MXH5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWI0-1", "uniprot_id": "F1MWI0_BOVIN", "mass": 51202.0, "length": 437, "protein_name": "Dynein regulatory complex protein 9", "gene_name": "IQCG", "organism": "Bovine", "refseq_name": "dynein regulatory complex protein 9 isoform X1", "refseq_ac": "XP_005201482", "gene_names_uniprotkb": "IQCG", "gene_names_refseq": "IQCG", "protein_names_uniprotkb": "Dynein regulatory complex protein 9; IQ domain-containing protein G", "protein_names_refseq": "dynein regulatory complex protein 9 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "39743588", "class_list": "", "function": "Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades. Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0030544 Hsp70 protein binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0042995 cell projection;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0036126 sperm flagellum", "go_biological_process": "GO:0044782 cilium organization;GO:0007288 sperm axoneme assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MWI0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWT0-1", "uniprot_id": "F1MWT0_BOVIN", "mass": 112316.0, "length": 1008, "protein_name": "alpha-mannosidase", "gene_name": "MAN2C1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MAN2C1", "gene_names_refseq": "", "protein_names_uniprotkb": "alpha-mannosidase; 3.2.1.24", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-8853383)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.2.1.24", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004559 alpha-mannosidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006013 mannose metabolic process;GO:0009313 oligosaccharide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MWT0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWK8-1", "uniprot_id": "F1MWK8_BOVIN", "mass": 118078.0, "length": 1070, "protein_name": "Inactive tyrosine-protein kinase 7", "gene_name": "PTK7", "organism": "Bovine", "refseq_name": "inactive tyrosine-protein kinase 7 precursor", "refseq_ac": "NP_001179894", "gene_names_uniprotkb": "PTK7", "gene_names_refseq": "PTK7", "protein_names_uniprotkb": "Inactive tyrosine-protein kinase 7; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; Tyrosine-protein kinase-like 7", "protein_names_refseq": "PTK7 protein tyrosine kinase 7; inactive tyrosine-protein kinase 7 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:514819)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008046 axon guidance receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0016020 membrane;GO:0070161 anchoring junction;GO:0030424 axon", "go_biological_process": "GO:0007155 cell adhesion;GO:0010976 positive regulation of neuron projection development;GO:0016477 cell migration;GO:0071300 cellular response to retinoic acid;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MWK8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWN1-1", "uniprot_id": "F1MWN1_BOVIN", "mass": 110608.0, "length": 973, "protein_name": "Exportin-2", "gene_name": "CSE1L", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CSE1L", "gene_names_refseq": "", "protein_names_uniprotkb": "Exportin-2; Chromosome segregation 1-like protein; Importin-alpha re-exporter", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031267 small GTPase binding;GO:0005049 nuclear export signal receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006611 protein export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MWN1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXP9-1", "uniprot_id": "F1MXP9_BOVIN", "mass": 359249.0, "length": 3262, "protein_name": "Cadherin-23", "gene_name": "CDH23", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CDH23", "gene_names_refseq": "", "protein_names_uniprotkb": "Cadherin-23; Otocadherin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction", "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007409 axonogenesis;GO:0030855 epithelial cell differentiation;GO:0006816 calcium ion transport;GO:0051480 regulation of cytosolic calcium ion concentration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MXP9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXZ5-1", "uniprot_id": "F1MXZ5_BOVIN", "mass": 55269.0, "length": 504, "protein_name": "Solute carrier family 38 member 3", "gene_name": "SLC38A3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC38A3", "gene_names_refseq": "", "protein_names_uniprotkb": "Solute carrier family 38 member 3", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-352230)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015180 L-alanine transmembrane transporter activity;GO:0140830 L-glutamine, sodium:proton antiporter activity;GO:0140831 L-asparagine, sodium:proton antiporter activity;GO:0140832 L-histidine, sodium:proton antiporter activity;GO:0015186 L-glutamine transmembrane transporter activity", "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0010585 glutamine secretion;GO:1903803 L-glutamine import across plasma membrane;GO:0015817 histidine transport;GO:0080144 intracellular amino acid homeostasis;GO:1903810 L-histidine import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MXZ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MX94-1", "uniprot_id": "F1MX94_BOVIN", "mass": 16363.0, "length": 145, "protein_name": "6-pyruvoyl tetrahydrobiopterin synthase", "gene_name": "PTS", "organism": "Bovine", "refseq_name": "6-pyruvoyl tetrahydrobiopterin synthase", "refseq_ac": "NP_001107009", "gene_names_uniprotkb": "PTS", "gene_names_refseq": "PTS", "protein_names_uniprotkb": "6-pyruvoyl tetrahydrobiopterin synthase; 4.2.3.12; PTP synthase; PTPS", "protein_names_refseq": "6-pyruvoyl tetrahydrobiopterin synthase", "tax_id": 9913, "disease": "", "pathway": " (bta:506860); (R-BTA-1474151)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A3Q1LXL4;A0A8J8XH99", "ec_number_list": "2.7.11.12;4.2.3.12", "go_molecular_function": "GO:0046872 metal ion binding;GO:0003874 6-pyruvoyltetrahydropterin synthase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006729 tetrahydrobiopterin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MX94-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MV05-1", "uniprot_id": "F1MV05_BOVIN", "mass": 66001.0, "length": 591, "protein_name": "Monooxygenase DBH like 2", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Monooxygenase DBH like 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005507 copper ion binding;GO:0004500 dopamine beta-monooxygenase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0030667 secretory granule membrane", "go_biological_process": "GO:0042420 dopamine catabolic process;GO:0006589 octopamine biosynthetic process;GO:0042421 norepinephrine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MV05-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUI1-1", "uniprot_id": "F1MUI1_BOVIN", "mass": 62012.0, "length": 560, "protein_name": "Tudor and KH domain-containing protein", "gene_name": "TDRKH", "organism": "Bovine", "refseq_name": "tudor and KH domain-containing protein isoform 1", "refseq_ac": "NP_001421810", "gene_names_uniprotkb": "TDRKH", "gene_names_refseq": "TDRKH", "protein_names_uniprotkb": "Tudor and KH domain-containing protein; Tudor domain-containing protein 2", "protein_names_refseq": "tudor and KH domain-containing protein isoform 1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "32486081;34129193", "class_list": "", "function": "Investigation of high correlation with carcass traits of SNPs of the PLCB1, C/EBPalpha, and TDRKH genes and the combinations of SNPs using the MDR method in the Hanwoo., [RefSeq, PubMed]; PIWIL3 Forms a Complex with TDRKH in Mammalian Oocytes. Publication Status: Online-Only, [RefSeq, PubMed]; Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs. May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0071546 pi-body;GO:0071547 piP-body;GO:0043186 P granule", "go_biological_process": "GO:0007283 spermatogenesis;GO:0009566 fertilization;GO:0030154 cell differentiation;GO:0007140 male meiotic nuclear division;GO:0034587 piRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1MUI1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MVN3-1", "uniprot_id": "F1MVN3_BOVIN", "mass": 75375.0, "length": 681, "protein_name": "Epithelial splicing regulatory protein 1", "gene_name": "ESRP1", "organism": "Bovine", "refseq_name": "epithelial splicing regulatory protein 1 isoform X5", "refseq_ac": "XP_005215731", "gene_names_uniprotkb": "ESRP1", "gene_names_refseq": "ESRP1; RBM35A", "protein_names_uniprotkb": "Epithelial splicing regulatory protein 1; RNA-binding motif protein 35A; RNA-binding protein 35A", "protein_names_refseq": "epithelial splicing regulatory protein 1 isoform X5", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. Regulates splicing and expression of genes involved in inner ear development, auditory hair cell differentiation, and cell fate specification in the cochlear epithelium., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0043484 regulation of RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MVN3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZF4-1", "uniprot_id": "F1MZF4_BOVIN", "mass": 31461.0, "length": 288, "protein_name": "Solute carrier family 25 member 45", "gene_name": "SLC25A45", "organism": "Bovine", "refseq_name": "solute carrier family 25 member 45", "refseq_ac": "NP_001192769", "gene_names_uniprotkb": "SLC25A45", "gene_names_refseq": "SLC25A45", "protein_names_uniprotkb": "Solute carrier family 25 member 45", "protein_names_refseq": "solute carrier family 25 member 45", "tax_id": 9913, "disease": "", "pathway": " (bta:517425)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0005743 mitochondrial inner membrane;GO:0005739 mitochondrion", "go_biological_process": "GO:0045329 carnitine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZF4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUP1-1", "uniprot_id": "F1MUP1_BOVIN", "mass": 85095.0, "length": 754, "protein_name": "glutamate carboxypeptidase II", "gene_name": "FOLH1", "organism": "Bovine", "refseq_name": "glutamate carboxypeptidase 2 isoform X1", "refseq_ac": "XP_024842790", "gene_names_uniprotkb": "FOLH1", "gene_names_refseq": "FOLH1B; FOLH1", "protein_names_uniprotkb": "glutamate carboxypeptidase II; 3.4.17.21", "protein_names_refseq": "glutamate carboxypeptidase 2 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-8963693)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.17.21", "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding;GO:0016805 dipeptidase activity;GO:0004180 carboxypeptidase activity;GO:0004181 metallocarboxypeptidase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUP1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MYU9-1", "uniprot_id": "F1MYU9_BOVIN", "mass": 68669.0, "length": 615, "protein_name": "Zinc finger and BTB domain-containing protein 44", "gene_name": "ZBTB44", "organism": "Bovine", "refseq_name": "zinc finger and BTB domain-containing protein 44 isoform X1", "refseq_ac": "XP_005226926", "gene_names_uniprotkb": "ZBTB44", "gene_names_refseq": "ZBTB44", "protein_names_uniprotkb": "Zinc finger and BTB domain-containing protein 44; BTB/POZ domain-containing protein 15", "protein_names_refseq": "zinc finger and BTB domain-containing protein 44 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MYU9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWS4-1", "uniprot_id": "F1MWS4_BOVIN", "mass": 51346.0, "length": 459, "protein_name": "E3 ubiquitin-protein ligase RNF25", "gene_name": "RNF25", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase RNF25 isoform X1", "refseq_ac": "XP_005202893", "gene_names_uniprotkb": "RNF25", "gene_names_refseq": "RNF25", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF25; 2.3.2.27; RING finger protein 25", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF25 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-983168)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "E3 ubiquitin-protein ligase that plays a key role in the RNF14-RNF25 translation quality control pathway, a pathway that takes place when a ribosome has stalled during translation, and which promotes ubiquitination and degradation of translation factors on stalled ribosomes. Catalyzes ubiquitination of RPS27A in response to ribosome collisions, promoting activation of RNF14. RNF25 catalyzes ubiquitination of other ribosomal proteins on stalled ribosomes, such as RPL0, RPL1, RPL12, RPS13 and RPS17. Also involved in ubiquitination and degradation of stalled ETF1/eRF1. Independently of its function in the response to stalled ribosomes, mediates ubiquitination and subsequent proteasomal degradation of NKD2. May also stimulate transcription mediated by NF-kappa-B via its interaction with RELA/p65., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.27;2.3.2.23;2.3.2.31;2.3.2.26;2.3.2.-;2.3.2.34;2.3.2.25;2.3.2.24", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0051059 NF-kappaB binding", "go_cellular_component": "GO:0005634 nucleus;GO:0022626 cytosolic ribosome", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0085020 protein K6-linked ubiquitination;GO:0160127 protein-RNA covalent cross-linking repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MWS4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWV0-1", "uniprot_id": "F1MWV0_BOVIN", "mass": 23756.0, "length": 204, "protein_name": "Guanylyl cyclase-activating protein 2", "gene_name": "GUCA1B", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GUCA1B", "gene_names_refseq": "", "protein_names_uniprotkb": "Guanylyl cyclase-activating protein 2; Guanylate cyclase activator 1B", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2514859)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0008048 calcium sensitive guanylate cyclase activator activity", "go_cellular_component": "GO:0001917 photoreceptor inner segment;GO:0120199 cone photoreceptor outer segment", "go_biological_process": "GO:0007601 visual perception;GO:0009966 regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MWV0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZK8-1", "uniprot_id": "F1MZK8_BOVIN", "mass": 83815.0, "length": 727, "protein_name": "Prolyl endopeptidase", "gene_name": "PREPL", "organism": "Bovine", "refseq_name": "prolyl endopeptidase-like isoform X1", "refseq_ac": "XP_024855156", "gene_names_uniprotkb": "PREPL", "gene_names_refseq": "PREPL", "protein_names_uniprotkb": "Prolyl endopeptidase; 3.4.21.-", "protein_names_refseq": "prolyl endopeptidase-like isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:533479)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005794 Golgi apparatus;GO:0005856 cytoskeleton;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0006508 proteolysis;GO:0043001 Golgi to plasma membrane protein transport;GO:0042147 retrograde transport, endosome to Golgi;GO:2000300 regulation of synaptic vesicle exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZK8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUR0-1", "uniprot_id": "F1MUR0_BOVIN", "mass": 23886.0, "length": 209, "protein_name": "Regulator of G-protein signaling 1", "gene_name": "RGS1", "organism": "Bovine", "refseq_name": "regulator of G-protein signaling 1", "refseq_ac": "NP_001185992", "gene_names_uniprotkb": "RGS1", "gene_names_refseq": "RGS1", "protein_names_uniprotkb": "Regulator of G-protein signaling 1", "protein_names_refseq": "regulator of G-protein signaling 1", "tax_id": 9913, "disease": "", "pathway": " (bta:540836); (R-BTA-416476); (R-BTA-418594)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0001965 G-protein alpha-subunit binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0009968 negative regulation of signal transduction;GO:0045744 negative regulation of G protein-coupled receptor signaling pathway;GO:0061737 leukotriene signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUR0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWT5-1", "uniprot_id": "F1MWT5_BOVIN", "mass": 17130.0, "length": 155, "protein_name": "Interleukin-1", "gene_name": "IL36RN", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IL36RN", "gene_names_refseq": "", "protein_names_uniprotkb": "Interleukin-1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-9014826)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0005149 interleukin-1 receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0001960 negative regulation of cytokine-mediated signaling pathway;GO:0032700 negative regulation of interleukin-17 production;GO:0006954 inflammatory response;GO:0019732 antifungal humoral response;GO:0032689 negative regulation of type II interferon production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MWT5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MX56-1", "uniprot_id": "F1MX56_BOVIN", "mass": 47053.0, "length": 415, "protein_name": "G-protein coupled receptor 83", "gene_name": "GPR83", "organism": "Bovine", "refseq_name": "G-protein coupled receptor 83", "refseq_ac": "XP_005215786", "gene_names_uniprotkb": "GPR83", "gene_names_refseq": "GPR83", "protein_names_uniprotkb": "G-protein coupled receptor 83", "protein_names_refseq": "G-protein coupled receptor 83", "tax_id": 9913, "disease": "", "pathway": " (bta:104968467); (R-BTA-418555)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "G-protein coupled receptor for PEN, a neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N). Acts through a G(i)- and G(q)-alpha-mediated pathway in response to PEN. Plays a role in food intake and body weight regulation. May contribute to the regulation of anxiety-related behaviors., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0008188 neuropeptide receptor activity;GO:0004983 neuropeptide Y receptor activity", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane;GO:0097730 non-motile cilium", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007631 feeding behavior", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MX56-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MV32-1", "uniprot_id": "F1MV32_BOVIN", "mass": 149302.0, "length": 1344, "protein_name": "Adhesion G protein-coupled receptor F5", "gene_name": "ADGRF5", "organism": "Bovine", "refseq_name": "adhesion G protein-coupled receptor F5 isoform X4", "refseq_ac": "XP_005223514", "gene_names_uniprotkb": "ADGRF5", "gene_names_refseq": "ADGRF5; GPR116", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor F5", "protein_names_refseq": "adhesion G protein-coupled receptor F5 isoform X4", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5683826)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0045177 apical part of cell;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0043129 surfactant homeostasis;GO:0042593 glucose homeostasis;GO:0006112 energy reserve metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MV32-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MV04-1", "uniprot_id": "F1MV04_BOVIN", "mass": 62355.0, "length": 568, "protein_name": "E3 ubiquitin-protein ligase ZFP91", "gene_name": "ZFP91", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase ZFP91 isoform X1", "refseq_ac": "XP_024831700", "gene_names_uniprotkb": "ZFP91", "gene_names_refseq": "ZFP91", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase ZFP91; 2.3.2.27; RING-type E3 ubiquitin transferase ZFP91; Zinc finger protein 91 homolog", "protein_names_refseq": "E3 ubiquitin-protein ligase ZFP91 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:529006)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA-binding transcription factor. Also acts as an atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development. May act as a regulator of multipotency in embryonic stem cells. Is a critical factor for proper spermatogenesis, involved in pre-piRNAs processing to generate mature piRNAs., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0004535 poly(A)-specific ribonuclease activity;GO:0000175 3'-5'-RNA exonuclease activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005634 nucleus;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0032502 developmental process;GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening;GO:0007283 spermatogenesis;GO:0034587 piRNA processing;GO:1990431 priRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MX01-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUU5-1", "uniprot_id": "F1MUU5_BOVIN", "mass": 101399.0, "length": 920, "protein_name": "NLR family member X1", "gene_name": "NLRX1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NLRX1", "gene_names_refseq": "", "protein_names_uniprotkb": "NLR family member X1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-936440); (R-BTA-9758274)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction. Instead, promotes autophagy by interacting with TUFM and subsequently recruiting the autophagy-related proteins ATG5 and ATG12. Also regulates MAVS-dependent NLRP3 inflammasome activation to attenuate apoptosis. Has no inhibitory function on NF-kappa-B signaling pathway, but enhances NF-kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species. Regulates viral mediated-inflammation and energy metabolism in a sex-dependent manner. In females, prevents uncontrolled inflammation and energy metabolism and thus, may contribute to the sex differences observed in infectious and inflammatory diseases., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0045087 innate immune response;GO:0043124 negative regulation of canonical NF-kappaB signal transduction;GO:0039536 negative regulation of RIG-I signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUU5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZJ0-1", "uniprot_id": "F1MZJ0_BOVIN", "mass": 72185.0, "length": 630, "protein_name": "Interleukin-23 receptor", "gene_name": "IL23R", "organism": "Bovine", "refseq_name": "interleukin-23 receptor isoform X3", "refseq_ac": "XP_005204542", "gene_names_uniprotkb": "IL23R", "gene_names_refseq": "IL-23R; IL23R", "protein_names_uniprotkb": "Interleukin-23 receptor", "protein_names_refseq": "interleukin-23 receptor isoform X3", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-9020933)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005143 interleukin-12 receptor binding;GO:0017046 peptide hormone binding;GO:0019955 cytokine binding;GO:0004925 prolactin receptor activity;GO:0042019 interleukin-23 binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane;GO:0072536 interleukin-23 receptor complex", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0032693 negative regulation of interleukin-10 production;GO:0008284 positive regulation of cell population proliferation;GO:0032496 response to lipopolysaccharide", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MVR0-1", "uniprot_id": "F1MVR0_BOVIN", "mass": 56685.0, "length": 500, "protein_name": "cyclin-dependent kinase", "gene_name": "CDK19", "organism": "Bovine", "refseq_name": "cyclin-dependent kinase 19", "refseq_ac": "NP_001192636", "gene_names_uniprotkb": "CDK19", "gene_names_refseq": "CDC2L6; CDK19", "protein_names_uniprotkb": "cyclin-dependent kinase; 2.7.11.22", "protein_names_refseq": "cell division cycle 2-like 6 (CDK8-like); cyclin-dependent kinase 19", "tax_id": 9913, "disease": "", "pathway": " (bta:511802)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:1990508 CKM complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MVR0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXP7-1", "uniprot_id": "F1MXP7_BOVIN", "mass": 100338.0, "length": 903, "protein_name": "Calcium-activated chloride channel regulator 1", "gene_name": "LOC784768", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC784768", "gene_names_refseq": "", "protein_names_uniprotkb": "Calcium-activated chloride channel regulator 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding;GO:0005229 intracellularly calcium-gated chloride channel activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0006816 calcium ion transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MXP7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWI2-1", "uniprot_id": "F1MWI2_BOVIN", "mass": 63603.0, "length": 578, "protein_name": "Nuclear receptor subfamily 1 group D member 1", "gene_name": "NR1D2", "organism": "Bovine", "refseq_name": "nuclear receptor subfamily 1 group D member 2 isoform X2", "refseq_ac": "XP_024842055", "gene_names_uniprotkb": "NR1D2", "gene_names_refseq": "NR1D2", "protein_names_uniprotkb": "Nuclear receptor subfamily 1 group D member 1; Rev-erbA-alpha; V-erbA-related protein 1", "protein_names_refseq": "nuclear receptor subfamily 1 group D member 2 isoform X2", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-383280)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0043197 dendritic spine;GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0055088 lipid homeostasis;GO:0019216 regulation of lipid metabolic process;GO:0050728 negative regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MWI2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MYL2-1", "uniprot_id": "F1MYL2_BOVIN", "mass": 78021.0, "length": 712, "protein_name": "Aryl hydrocarbon receptor nuclear translocator 2", "gene_name": "ARNT2", "organism": "Bovine", "refseq_name": "aryl hydrocarbon receptor nuclear translocator 2 isoform X2", "refseq_ac": "XP_024837636", "gene_names_uniprotkb": "ARNT2", "gene_names_refseq": "ARNT2", "protein_names_uniprotkb": "Aryl hydrocarbon receptor nuclear translocator 2", "protein_names_refseq": "aryl hydrocarbon receptor nuclear translocator 2 isoform X2", "tax_id": 9913, "disease": "", "pathway": " (bta:533445); (R-BTA-211945); (R-BTA-211976); (R-BTA-211981); (R-BTA-8937144); (R-BTA-9768919)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function. Specifically recognizes the xenobiotic response element (XRE)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0046983 protein dimerization activity;GO:0046982 protein heterodimerization activity;GO:0017162 aryl hydrocarbon receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex;GO:0005654 nucleoplasm;GO:0034751 aryl hydrocarbon receptor complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0001666 response to hypoxia;GO:0001701 in utero embryonic development;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007420 brain development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MYL2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MX44-1", "uniprot_id": "F1MX44_BOVIN", "mass": 25369.0, "length": 222, "protein_name": "Glutathione S-transferase", "gene_name": "GSTA5", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GSTA5", "gene_names_refseq": "", "protein_names_uniprotkb": "Glutathione S-transferase; 2.5.1.18", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-156590); (R-BTA-189483); (R-BTA-9748787)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.5.1.18;5.2.1.2;1.20.4.2;1.8.5.1;4.1.1.84;5.3.99.2;1.11.1.-;5.3.3.-;4.4.1.20", "go_molecular_function": "GO:0004364 glutathione transferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MX44-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXS4-1", "uniprot_id": "F1MXS4_BOVIN", "mass": 66415.0, "length": 600, "protein_name": "DNA polymerase alpha subunit B", "gene_name": "POLA2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "POLA2", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA polymerase alpha subunit B", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-113501); (R-BTA-174411); (R-BTA-174430); (R-BTA-68952); (R-BTA-68962); (R-BTA-69091); (R-BTA-69166); (R-BTA-69183)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1, an accessory subunit POLA2 and two primase subunits, the catalytic subunit PRIM1 and the regulatory subunit PRIM2) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUD0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUD1-1", "uniprot_id": "F1MUD1_BOVIN", "mass": 48435.0, "length": 423, "protein_name": "G protein-activated inward rectifier potassium channel 2", "gene_name": "KCNJ6", "organism": "Bovine", "refseq_name": "G protein-activated inward rectifier potassium channel 2", "refseq_ac": "XP_059745568", "gene_names_uniprotkb": "KCNJ6", "gene_names_refseq": "KCNJ6", "protein_names_uniprotkb": "G protein-activated inward rectifier potassium channel 2; Cardiac inward rectifier; G protein-activated inward rectifier potassium channel 4; Heart KATP channel; Inward rectifier K(+) channel Kir3.4; KATP-1; Potassium channel, inwardly rectifying subfamily J member 5; Potassium channel, inwardly rectifying subfamily J member 6", "protein_names_refseq": "G protein-activated inward rectifier potassium channel 2", "tax_id": 9913, "disease": "", "pathway": " (bta:520743)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.-.-", "go_molecular_function": "GO:0015467 G-protein activated inward rectifier potassium channel activity", "go_cellular_component": "GO:1990566 I(KACh) inward rectifier potassium channel complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUD1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUF5-1", "uniprot_id": "F1MUF5_BOVIN", "mass": 220620.0, "length": 1906, "protein_name": "Adenylate kinase 9", "gene_name": "AK9", "organism": "Bovine", "refseq_name": "adenylate kinase 9 isoform X2", "refseq_ac": "XP_005210886", "gene_names_uniprotkb": "AK9", "gene_names_refseq": "AK9", "protein_names_uniprotkb": "Adenylate kinase 9; 2.7.4.4; 2.7.4.6", "protein_names_refseq": "adenylate kinase 9 isoform X2", "tax_id": 9913, "disease": "", "pathway": " (bta:504511); (R-BTA-499943)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "39743588", "class_list": "", "function": "Broad-specificity nucleoside phosphate kinase involved in cellular nucleotide homeostasis by catalyzing nucleoside-phosphate interconversions. Similar to other adenylate kinases, preferentially catalyzes the phosphorylation of the nucleoside monophosphate AMP with ATP as phosphate donor to produce ADP. In vitro, can also catalyze the phosphorylation of CMP, dAMP and dCMP and use GTP as an alternate phosphate donor. Moreover, exhibits a diphosphate kinase activity, producing ATP, CTP, GTP, UTP, TTP, dATP, dCTP and dGTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donors. For this activity shows the following substrate preference CDP > UDP > ADP > TDP., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.4.10;2.7.4.6;2.7.4.3;2.7.4.4;2.7.4.14;3.1.11.-;2.7.11.1;2.7.13.3;2.7.4.18;3.1.24.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0004550 nucleoside diphosphate kinase activity;GO:0033862 UMP kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031514 motile cilium", "go_biological_process": "GO:0006225 UDP biosynthetic process;GO:0046705 CDP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MUF5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUG8-1", "uniprot_id": "F1MUG8_BOVIN", "mass": 67079.0, "length": 619, "protein_name": "Solute carrier family 7 member 3", "gene_name": "SLC7A3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC7A3", "gene_names_refseq": "", "protein_names_uniprotkb": "Solute carrier family 7 member 3", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-352230)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000064 L-ornithine transmembrane transporter activity;GO:0015171 amino acid transmembrane transporter activity;GO:0015189 L-lysine transmembrane transporter activity;GO:0061459 L-arginine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006865 amino acid transport;GO:0097638 L-arginine import across plasma membrane;GO:0097639 L-lysine import across plasma membrane;GO:0097640 L-ornithine import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUG8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUI2-1", "uniprot_id": "F1MUI2_BOVIN", "mass": 36294.0, "length": 322, "protein_name": "Olfactory receptor", "gene_name": "OR52B2", "organism": "Bovine", "refseq_name": "olfactory receptor 52B2", "refseq_ac": "NP_001376713", "gene_names_uniprotkb": "OR52B2", "gene_names_refseq": "OR52B2", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 52B2", "tax_id": 9913, "disease": "", "pathway": " (bta:507282)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUI2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUI5-1", "uniprot_id": "F1MUI5_BOVIN", "mass": 51233.0, "length": 450, "protein_name": "Acid sphingomyelinase-like phosphodiesterase", "gene_name": "SMPDL3A", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SMPDL3A", "gene_names_refseq": "", "protein_names_uniprotkb": "Acid sphingomyelinase-like phosphodiesterase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cyclic-nucleotide phosphodiesterase that acts as a negative regulator of innate immunity by mediating degradation of 2',3'-cGAMP, thereby inhibiting the cGAS-STING signaling. Specifically linearizes 2',3'-cGAMP into 2'5'-bond pGpA and further hydrolyzes pGpA to produce GpA. Also has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP. Has in vitro activity with p-nitrophenyl-TMP. Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates. Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine. Does not have sphingomyelin phosphodiesterase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008081 phosphoric diester hydrolase activity;GO:0004767 sphingomyelin phosphodiesterase activity;GO:0017111 ribonucleoside triphosphate phosphatase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:0009143 nucleoside triphosphate catabolic process;GO:0006685 sphingomyelin catabolic process;GO:0160049 negative regulation of cGAS/STING signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUI5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUL1-1", "uniprot_id": "F1MUL1_BOVIN", "mass": 21253.0, "length": 182, "protein_name": "Ferritin", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Ferritin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron., [UniProtKB, UniProtKB]; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.11.1.27;1.16.3.1;1.11.1.9;1.16.3.4", "go_molecular_function": "GO:0008198 ferrous iron binding;GO:0004322 ferroxidase activity;GO:0008199 ferric iron binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005764 lysosome;GO:0005776 autophagosome", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0006826 iron ion transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUL1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUP3-1", "uniprot_id": "F1MUP3_BOVIN", "mass": 45862.0, "length": 399, "protein_name": "Translocation protein SEC62", "gene_name": "SEC62", "organism": "Bovine", "refseq_name": "translocation protein SEC62", "refseq_ac": "NP_001192533", "gene_names_uniprotkb": "SEC62", "gene_names_refseq": "SEC62; TLOC1", "protein_names_uniprotkb": "Translocation protein SEC62", "protein_names_refseq": "translocation protein 1; translocation protein SEC62", "tax_id": 9913, "disease": "", "pathway": " (bta:538938)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008320 protein transmembrane transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0031204 post-translational protein targeting to membrane, translocation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUP3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUR7-1", "uniprot_id": "F1MUR7_BOVIN", "mass": 57648.0, "length": 541, "protein_name": "Reticulophagy regulator family member 2", "gene_name": "RETREG2", "organism": "Bovine", "refseq_name": "reticulophagy regulator 2", "refseq_ac": "NP_001192537", "gene_names_uniprotkb": "RETREG2", "gene_names_refseq": "C2H2orf17; FAM134A; RETREG2", "protein_names_uniprotkb": "Reticulophagy regulator family member 2", "protein_names_refseq": "family with sequence similarity 134 member A; reticulophagy regulator 2", "tax_id": 9913, "disease": "", "pathway": " (bta:507475)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0140506 endoplasmic reticulum-autophagosome adaptor activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUR7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUS3-1", "uniprot_id": "F1MUS3_BOVIN", "mass": 47147.0, "length": 430, "protein_name": "Zona pellucida-like domain-containing protein 1", "gene_name": "ZPLD1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ZPLD1", "gene_names_refseq": "", "protein_names_uniprotkb": "Zona pellucida-like domain-containing protein 1; Cupulin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Glycoprotein which is a component of the gelatinous extracellular matrix in the cupulae of the vestibular organ., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUS3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUS4-1", "uniprot_id": "F1MUS4_BOVIN", "mass": 35672.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "OR9A7", "organism": "Bovine", "refseq_name": "olfactory receptor family 9 subfamily A member 7", "refseq_ac": "NP_001376940", "gene_names_uniprotkb": "OR9A7", "gene_names_refseq": "OR9A7", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 9A4; olfactory receptor family 9 subfamily A member 7", "tax_id": 9913, "disease": "", "pathway": " (bta:519161)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUS4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUT8-1", "uniprot_id": "F1MUT8_BOVIN", "mass": 60256.0, "length": 560, "protein_name": "Amino acid transporter", "gene_name": "SLC1A7", "organism": "Bovine", "refseq_name": "excitatory amino acid transporter 5", "refseq_ac": "NP_001192833", "gene_names_uniprotkb": "SLC1A7", "gene_names_refseq": "SLC1A7", "protein_names_uniprotkb": "Amino acid transporter", "protein_names_refseq": "excitatory amino acid transporter 5", "tax_id": 9913, "disease": "", "pathway": " (bta:523673); (R-BTA-210500); (R-BTA-9958863)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015175 neutral L-amino acid transmembrane transporter activity;GO:0015501 glutamate:sodium symporter activity;GO:0005313 L-glutamate transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0001504 neurotransmitter uptake;GO:0070633 transepithelial transport;GO:0015813 L-glutamate transmembrane transport;GO:0150104 transport across blood-brain barrier;GO:0070778 L-aspartate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUT8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUU2-1", "uniprot_id": "F1MUU2_BOVIN", "mass": 58818.0, "length": 539, "protein_name": "Serine/threonine-protein kinase 35", "gene_name": "STK35", "organism": "Bovine", "refseq_name": "serine/threonine-protein kinase 35 isoform X1", "refseq_ac": "XP_010809823", "gene_names_uniprotkb": "STK35", "gene_names_refseq": "STK35", "protein_names_uniprotkb": "Serine/threonine-protein kinase 35; 2.7.11.1; Serine/threonine-protein kinase 35 L1", "protein_names_refseq": "serine/threonine-protein kinase 35 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0010972 negative regulation of G2/M transition of mitotic cell cycle;GO:0110031 negative regulation of G2/MI transition of meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUU2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUU8-1", "uniprot_id": "F1MUU8_BOVIN", "mass": 34906.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "OR8D4", "organism": "Bovine", "refseq_name": "olfactory receptor family 8 subfamily D member 4", "refseq_ac": "NP_001376824", "gene_names_uniprotkb": "OR8D4", "gene_names_refseq": "OR8D4", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor family 8 subfamily D member 4", "tax_id": 9913, "disease": "", "pathway": " (bta:512037)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUU8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUX1-1", "uniprot_id": "F1MUX1_BOVIN", "mass": 62847.0, "length": 554, "protein_name": "Methyl-CpG-binding domain protein 4", "gene_name": "MBD4", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MBD4", "gene_names_refseq": "", "protein_names_uniprotkb": "Methyl-CpG-binding domain protein 4; 3.2.2.-", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-110329); (R-BTA-110357)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.11.2;3.1.21.-;3.1.-.-;3.2.2.-", "go_molecular_function": "GO:0003677 DNA binding;GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck", "go_biological_process": "GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUX1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUY1-1", "uniprot_id": "F1MUY1_BOVIN", "mass": 35201.0, "length": 311, "protein_name": "Olfactory receptor", "gene_name": "OR5E1", "organism": "Bovine", "refseq_name": "olfactory receptor family 5 subfamily E member 1", "refseq_ac": "NP_001377093", "gene_names_uniprotkb": "OR5E1", "gene_names_refseq": "OR5E1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 1030; olfactory receptor family 5 subfamily E member 1", "tax_id": 9913, "disease": "", "pathway": " (bta:539064)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0060170 ciliary membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0048512 circadian behavior;GO:0060019 radial glial cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUY8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUZ0-1", "uniprot_id": "F1MUZ0_BOVIN", "mass": 34694.0, "length": 305, "protein_name": "EBNA1 binding protein 2", "gene_name": "EBNA1BP2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "EBNA1BP2", "gene_names_refseq": "", "protein_names_uniprotkb": "EBNA1 binding protein 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-6791226)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for the processing of the 27S pre-rRNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor;GO:0005694 chromosome;GO:0034399 nuclear periphery", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUZ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUZ7-1", "uniprot_id": "F1MUZ7_BOVIN", "mass": 50557.0, "length": 438, "protein_name": "Purple acid phosphatase", "gene_name": "ACP7", "organism": "Bovine", "refseq_name": "acid phosphatase type 7 precursor", "refseq_ac": "NP_001179461", "gene_names_uniprotkb": "ACP7", "gene_names_refseq": "ACP7; 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MV21-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MV28-1", "uniprot_id": "F1MV28_BOVIN", "mass": 42435.0, "length": 399, "protein_name": "Sphingosine 1-phosphate receptor 5", "gene_name": "S1PR5", "organism": "Bovine", "refseq_name": "sphingosine 1-phosphate receptor 5", "refseq_ac": "NP_001179404", "gene_names_uniprotkb": "S1PR5", "gene_names_refseq": "EDG8; S1PR5", "protein_names_uniprotkb": "Sphingosine 1-phosphate receptor 5; Endothelial differentiation G-protein-coupled receptor 8; Sphingosine 1-phosphate receptor Edg-8", "protein_names_refseq": "endothelial differentiation, sphingolipid G-protein-coupled receptor, 8; sphingosine 1-phosphate receptor 5", "tax_id": 9913, "disease": "", "pathway": " (bta:517533); (R-BTA-418594); (R-BTA-419408)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0038036 sphingosine-1-phosphate receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0098793 presynapse", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MV28-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MV39-1", "uniprot_id": "F1MV39_BOVIN", "mass": 21483.0, "length": 184, "protein_name": "Bcl-2-like protein 10", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Bcl-2-like protein 10; Anti-apoptotic protein Boo; Apoptosis regulator Bcl-B", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Promotes cell survival by suppressing apoptosis induced by BAX but not BAK. Increases binding of AHCYL1/IRBIT to ITPR1. Reduces ITPR1-mediated calcium release from the endoplasmic reticulum cooperatively with AHCYL1/IRBIT under normal cellular conditions. Under apoptotic stress conditions, dissociates from ITPR1 and is displaced from mitochondria-associated endoplasmic reticulum membranes, leading to increased Ca(2+) transfer to mitochondria which promotes apoptosis. Required for the correct formation of the microtubule organizing center during oocyte cell division, potentially via regulation of protein abundance and localization of other microtubule organizing center components such as AURKA and TPX2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015267 channel activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum;GO:0005819 spindle;GO:0031965 nuclear membrane", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage;GO:0001836 release of cytochrome c from mitochondria;GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MV39-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MV66-1", "uniprot_id": "F1MV66_BOVIN", "mass": 45253.0, "length": 389, "protein_name": "2'-5' oligoadenylate synthase", "gene_name": "OAS1Y", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "OAS1Y", "gene_names_refseq": "", "protein_names_uniprotkb": "2'-5' oligoadenylate synthase; 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0071396 cellular response to lipid", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MVH2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MVH6-1", "uniprot_id": "F1MVH6_BOVIN", "mass": 36950.0, "length": 329, "protein_name": "Hexosyltransferase", "gene_name": "B3GALT6", "organism": "Bovine", "refseq_name": "beta-1,3-galactosyltransferase 6", "refseq_ac": "XP_002694179", "gene_names_uniprotkb": "B3GALT6", "gene_names_refseq": "B3GALT6", "protein_names_uniprotkb": "Hexosyltransferase; 2.4.1.-", "protein_names_refseq": "beta-1,3-galactosyltransferase 6", "tax_id": 9913, "disease": "", "pathway": " (bta:522406); (R-BTA-1971475)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. Has a preference for galactose-beta-1,4-xylose that is found in the linker region of glycosaminoglycans, such as heparan sulfate and chondroitin sulfate. 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[provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MW42-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MW44-1", "uniprot_id": "F1MW44_BOVIN", "mass": 82804.0, "length": 732, "protein_name": "Coagulation factor XIII A chain", "gene_name": "F13A1", "organism": "Bovine", "refseq_name": "coagulation factor XIII A chain", "refseq_ac": "NP_001161366", "gene_names_uniprotkb": "F13A1", "gene_names_refseq": "F13A1", "protein_names_uniprotkb": "Coagulation factor XIII A chain; 2.3.2.13; Protein-glutamine gamma-glutamyltransferase A chain; Transglutaminase A chain", "protein_names_refseq": "blood coagulation factor XIII A1 subunit; coagulation factor XIII A chain; coagulation factor XIII, A1 polypeptide; coagulation factor XIIIa; protein-glutamine gamma-glutamyltransferase A chain; transglutaminase A chain", "tax_id": 9913, "disease": "", "pathway": " (bta:617881); (R-BTA-114608); (R-BTA-9769733)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "12669118", "class_list": "", "function": "Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin., [UniProtKB, UniProtKB, UniProtKB]; Kinetic and structural analysis of interactions between thrombin and the Factor XIII activation peptide, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.21.69;2.3.2.13;3.5.1.44;3.4.21.7;3.4.21.5;3.4.-.-;2.3.1.-;1.8.3.5;3.4.21.46", "go_molecular_function": "GO:0046872 metal ion binding;GO:0003810 protein-glutamine gamma-glutamyltransferase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm", "go_biological_process": "GO:0018149 peptide cross-linking;GO:0072378 blood coagulation, fibrin clot formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MW44-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MW70-1", "uniprot_id": "F1MW70_BOVIN", "mass": 38266.0, "length": 345, "protein_name": "Dual specificity protein phosphatase 12", "gene_name": "DUSP12", "organism": "Bovine", "refseq_name": "dual specificity protein phosphatase 12", "refseq_ac": "XP_002685893", "gene_names_uniprotkb": "DUSP12", "gene_names_refseq": "DUSP12", "protein_names_uniprotkb": "Dual specificity protein phosphatase 12; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "dual specificity protein phosphatase 12", "tax_id": 9913, "disease": "", "pathway": " (bta:505302)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Dual specificity phosphatase; can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues. Can dephosphorylate glucokinase (in vitro). Has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate and other in vitro substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, 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establishment of protein localization;GO:0099560 synaptic membrane adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MWA2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWC4-1", "uniprot_id": "F1MWC4_BOVIN", "mass": 78946.0, "length": 718, "protein_name": "Arginyl aminopeptidase like 1", "gene_name": "RNPEPL1", "organism": "Bovine", "refseq_name": "aminopeptidase RNPEPL1", "refseq_ac": "XP_024846091", "gene_names_uniprotkb": "RNPEPL1", "gene_names_refseq": "RNPEPL1", "protein_names_uniprotkb": "Arginyl aminopeptidase like 1", "protein_names_refseq": "aminopeptidase RNPEPL1", "tax_id": 9913, "disease": "", "pathway": " (bta:511497)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0070006 metalloaminopeptidase 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MWC9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWD4-1", "uniprot_id": "F1MWD4_BOVIN", "mass": 24453.0, "length": 215, "protein_name": "Calcium binding protein 7", "gene_name": "CABP7", "organism": "Bovine", "refseq_name": "calcium-binding protein 7", "refseq_ac": "XP_024833590", "gene_names_uniprotkb": "CABP7", "gene_names_refseq": "CABP7", "protein_names_uniprotkb": "Calcium binding protein 7", 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(R-BTA-977606)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0022829 wide pore channel activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005579 membrane attack complex;GO:0044218 other organism cell membrane", "go_biological_process": "GO:0031640 killing of cells of another organism;GO:0006958 complement activation, classical pathway;GO:0006956 complement activation;GO:0006957 complement activation, alternative pathway;GO:0160257 complement activation, GZMK pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MX87-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MX92-1", "uniprot_id": "F1MX92_BOVIN", "mass": 34627.0, "length": 312, "protein_name": "Olfactory receptor family 10 subfamily K member 2", "gene_name": "OR10K2", "organism": "Bovine", "refseq_name": "olfactory receptor family 10 subfamily K member 2", "refseq_ac": "NP_001377072", "gene_names_uniprotkb": "OR10K2", "gene_names_refseq": "OR10K2", "protein_names_uniprotkb": "Olfactory receptor family 10 subfamily K member 2", "protein_names_refseq": "olfactory receptor family 10 subfamily K member 2", "tax_id": 9913, "disease": "", "pathway": " (bta:532341)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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"Myosin VC", "protein_names_refseq": "unconventional myosin-Vc", "tax_id": 9913, "disease": "", "pathway": " (bta:532574)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0015629 actin cytoskeleton;GO:0016020 membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0030050 vesicle transport along actin filament", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MX93-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXC9-1", "uniprot_id": "F1MXC9_BOVIN", "mass": 49149.0, "length": 459, "protein_name": "Zinc finger and BTB domain containing 12", "gene_name": "ZBTB12", "organism": "Bovine", "refseq_name": "zinc finger and BTB domain-containing protein 12", "refseq_ac": "XP_005223753", "gene_names_uniprotkb": "ZBTB12", "gene_names_refseq": "ZBTB12", "protein_names_uniprotkb": "Zinc finger and BTB domain containing 12", "protein_names_refseq": "zinc finger and BTB domain-containing protein 12", "tax_id": 9913, "disease": "", "pathway": " (bta:100336034)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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"go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0002682 regulation of immune system process;GO:0001817 regulation of cytokine production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MXC9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXD0-1", "uniprot_id": "F1MXD0_BOVIN", "mass": 41461.0, "length": 373, "protein_name": "28S rRNA (uridine-N(3))-methyltransferase", "gene_name": "SPOUT1", "organism": "Bovine", "refseq_name": "putative methyltransferase C9orf114 homolog isoform X2", "refseq_ac": "XP_005213493", "gene_names_uniprotkb": "SPOUT1", "gene_names_refseq": "SPOUT1", "protein_names_uniprotkb": "28S rRNA (uridine-N(3))-methyltransferase; Centromere protein 32; Kinetochore-associated protein; SPOUT domain-containing methyltransferase 1", "protein_names_refseq": "putative methyltransferase C9orf114 homolog 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0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035198 miRNA binding;GO:0070042 rRNA (uridine-N3-)-methyltransferase activity;GO:1904047 S-adenosyl-L-methionine binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000776 kinetochore;GO:0031616 spindle pole centrosome;GO:0072686 mitotic spindle", "go_biological_process": "GO:0051661 maintenance of centrosome location;GO:0035196 miRNA processing;GO:0070475 rRNA base methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MXD0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXD3-1", "uniprot_id": "F1MXD3_BOVIN", "mass": 37992.0, "length": 359, "protein_name": "H6 family homeobox 3", "gene_name": "HMX3", "organism": "Bovine", "refseq_name": "homeobox protein HMX3", "refseq_ac": "XP_003587958", "gene_names_uniprotkb": "HMX3", "gene_names_refseq": "HMX3", "protein_names_uniprotkb": "H6 family homeobox 3", "protein_names_refseq": "homeobox protein HMX3", "tax_id": 9913, "disease": "", "pathway": " (bta:522046)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0043583 ear development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MXD3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXF0-1", "uniprot_id": "F1MXF0_BOVIN", "mass": 49457.0, "length": 449, "protein_name": "Antizyme inhibitor 2-like", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Antizyme inhibitor 2-like", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016829 lyase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0042177 negative regulation of protein catabolic process;GO:0033387 putrescine biosynthetic process from arginine, via ornithine;GO:1902269 positive regulation of polyamine transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MXF0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXG2-1", "uniprot_id": "F1MXG2_BOVIN", "mass": 50473.0, "length": 436, "protein_name": "Neuropeptide FF receptor 2", "gene_name": "NPFFR2", "organism": "Bovine", "refseq_name": "neuropeptide FF receptor 2", "refseq_ac": "XP_005208183", "gene_names_uniprotkb": "NPFFR2", "gene_names_refseq": "NPFFR2", "protein_names_uniprotkb": "Neuropeptide FF receptor 2; G-protein coupled receptor 74", "protein_names_refseq": "neuropeptide FF receptor 2", "tax_id": 9913, "disease": "", "pathway": " (bta:530560); (R-BTA-389397); (R-BTA-416476)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031628 opioid receptor binding;GO:0004930 G protein-coupled receptor activity;GO:0008188 neuropeptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0032870 cellular response to hormone stimulus;GO:0043408 regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MXG2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXG5-1", "uniprot_id": "F1MXG5_BOVIN", "mass": 89544.0, "length": 843, "protein_name": "GLIS family zinc finger 1", "gene_name": "GLIS1", "organism": "Bovine", "refseq_name": "zinc finger protein GLIS1 isoform X1", "refseq_ac": "XP_010801861", "gene_names_uniprotkb": "GLIS1", "gene_names_refseq": "GLIS1", "protein_names_uniprotkb": "GLIS family zinc finger 1", "protein_names_refseq": "zinc finger protein GLIS1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:541222)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0016604 nuclear body", "go_biological_process": "GO:0010454 negative regulation of cell fate commitment;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045444 fat cell differentiation;GO:0001649 osteoblast differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MXG5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXH9-1", "uniprot_id": "F1MXH9_BOVIN", "mass": 18836.0, "length": 166, "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "organism": "Bovine", "refseq_name": "late histone H2B.L4", "refseq_ac": "XP_015317060", "gene_names_uniprotkb": "", "gene_names_refseq": "LOC616431", "protein_names_uniprotkb": "Core Histone H2A/H2B/H3 domain-containing protein", "protein_names_refseq": "late histone H2B.L4", "tax_id": 9913, "disease": "", "pathway": " (bta:101902714); (bta:616431)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AAA9TH59", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0046982 protein heterodimerization activity;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MXH9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXL7-1", "uniprot_id": "F1MXL7_BOVIN", "mass": 9157.0, "length": 84, "protein_name": "Uncharacterized protein", "gene_name": "LOC100126230", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC100126230", "gene_names_refseq": "", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0040016 embryonic cleavage;GO:0040019 positive regulation of embryonic development;GO:2000184 positive regulation of progesterone biosynthetic process;GO:0001550 ovarian cumulus expansion;GO:1904146 positive regulation of meiotic cell cycle process involved in oocyte maturation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MXL7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXN8-1", "uniprot_id": "F1MXN8_BOVIN", "mass": 37784.0, "length": 330, "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5", "gene_name": "ST6GALNAC5", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ST6GALNAC5", "gene_names_refseq": "", "protein_names_uniprotkb": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; GD1 alpha synthase; GalNAc alpha-2,6-sialyltransferase V; ST6GalNAc V; Sialyltransferase 7E", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-4085001); (R-BTA-9840309)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Predominantly catalyzes the biosynthesis of ganglioside GD1alpha from GM1b in the brain, by transferring the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the GalNAc residue on the NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc sequence of GM1b. GD1alpha is a critical molecule in the communication and interaction between neuronal cells and their supportive cells, particularly in brain tissues, and functions as an adhesion molecule in the process of metastasis. Also shows activity towards sialyl Lc4Cer (N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine) generating disialyl Lc4Cer, which can lead to the synthesis of disialyl Lewis a (Le(a)), suggested to be a cancer-associated antigen., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.3.7;2.4.99.-", "go_molecular_function": "GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:0009311 oligosaccharide metabolic process;GO:0001574 ganglioside biosynthetic process", "synthesized_glycan_count": 550, "hit_score": 0.1, "record_id": "F1MXN8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXP2-1", "uniprot_id": "F1MXP2_BOVIN", "mass": 36035.0, "length": 321, "protein_name": "Olfactory receptor", "gene_name": "OR52N1", "organism": "Bovine", "refseq_name": "olfactory receptor family 52 subfamily N member 1", "refseq_ac": "NP_001193592", "gene_names_uniprotkb": "OR52N1", "gene_names_refseq": "OR52N1", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 52N1-like; olfactory receptor family 52 subfamily N member 1; olfactory receptor, family 52, subfamily N, member 1 (predicted)-like", "tax_id": 9913, "disease": "", "pathway": " (bta:618803)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MXP2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXR1-1", "uniprot_id": "F1MXR1_BOVIN", "mass": 35740.0, "length": 313, "protein_name": "Olfactory receptor family 8 subfamily K member 5", "gene_name": "OR8K5", "organism": "Bovine", "refseq_name": "olfactory receptor family 8 subfamily K member 5", "refseq_ac": "NP_001377568", "gene_names_uniprotkb": "OR8K5", "gene_names_refseq": "OR8K5", "protein_names_uniprotkb": "Olfactory receptor family 8 subfamily K member 5", "protein_names_refseq": "olfactory receptor family 8 subfamily K member 5; olfactory receptor, family 8, subfamily K, member 5-like", "tax_id": 9913, "disease": "", "pathway": " (bta:790274)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0051045 negative regulation of membrane protein ectodomain proteolysis;GO:0034097 response to cytokine;GO:0009725 response to hormone", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MY12-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MY32-1", "uniprot_id": "F1MY32_BOVIN", "mass": 13489.0, "length": 116, "protein_name": "Lymphocyte antigen 6 complex locus protein G5c", "gene_name": "LY6G5C", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LY6G5C", "gene_names_refseq": "", "protein_names_uniprotkb": "Lymphocyte antigen 6 complex locus protein G5c", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May have a role in hematopoietic cell differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MY32-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MY47-1", "uniprot_id": "F1MY47_BOVIN", "mass": 74492.0, "length": 676, "protein_name": "Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3", "gene_name": "LRIT3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LRIT3", "gene_names_refseq": "", "protein_names_uniprotkb": "Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in the synapse formation and synaptic transmission between cone photoreceptor cells and retinal bipolar cells. Required for normal transmission of a light-evoked stimulus from the cone photoreceptor cells to the ON-bipolar cells and ON-ganglion cells in the inner retina. Required in retinal ON-bipolar cells for normal localization of the cation channel TRPM1 at dendrite tips. Seems to play a specific role in synaptic contacts made by ON-bipolar cells with cone photoreceptor pedicles. May also have a role in cone synapse formation. Might facilitate FGFR1 exit from the endoplasmic reticulum to the Golgi. Could be a regulator of the FGFRs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0051286 cell tip;GO:0030425 dendrite;GO:0043204 perikaryon;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0040036 regulation of fibroblast growth factor receptor signaling pathway;GO:0007601 visual perception", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MY47-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MY53-1", "uniprot_id": "F1MY53_BOVIN", "mass": 46728.0, "length": 423, "protein_name": "Neuromedin U receptor 1", "gene_name": "NMUR1", "organism": "Bovine", "refseq_name": "neuromedin-U receptor 1", "refseq_ac": "XP_059735290", "gene_names_uniprotkb": "NMUR1", "gene_names_refseq": "NMUR1", "protein_names_uniprotkb": "Neuromedin U receptor 1", "protein_names_refseq": "neuromedin-U receptor 1", "tax_id": 9913, "disease": "", "pathway": " (bta:100848851); (R-BTA-375276); (R-BTA-416476); (R-BTA-418594)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Receptor for the neuromedin-U and neuromedin-S neuropeptides., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008188 neuropeptide receptor activity;GO:0001607 neuromedin U receptor activity;GO:0042924 neuromedin U binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0097731 9+0 non-motile cilium", "go_biological_process": "GO:0006939 smooth muscle contraction;GO:0007218 neuropeptide signaling pathway;GO:0019722 calcium-mediated signaling;GO:0050850 positive regulation of calcium-mediated signaling;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MY53-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MY58-1", "uniprot_id": "F1MY58_BOVIN", "mass": 67372.0, "length": 613, "protein_name": "Target of myb1 like 1 membrane trafficking protein", "gene_name": "TOM1L1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TOM1L1", "gene_names_refseq": "", "protein_names_uniprotkb": "Target of myb1 like 1 membrane trafficking protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0030295 protein kinase activator activity;GO:0030276 clathrin binding;GO:0035091 phosphatidylinositol binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005768 endosome;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction;GO:0015031 protein transport;GO:0045839 negative regulation of mitotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MY58-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MY60-1", "uniprot_id": "F1MY60_BOVIN", "mass": 65223.0, "length": 582, "protein_name": "Hyaluronan synthase 1", "gene_name": "HAS1", "organism": "Bovine", "refseq_name": "hyaluronan synthase 1", "refseq_ac": "XP_024834545", "gene_names_uniprotkb": "HAS1", "gene_names_refseq": "HAS1", "protein_names_uniprotkb": "Hyaluronan synthase 1; 2.4.1.212; Hyaluronate synthase 1; Hyaluronic acid synthase 1", "protein_names_refseq": "hyaluronan synthase 1", "tax_id": 9913, "disease": "", "pathway": " (bta:282820); (R-BTA-2142845)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential for the synthesis of hyaluronan, a major component of most extracellular matrices that has a structural role in tissue architecture and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.212", "go_molecular_function": "GO:0050501 hyaluronan synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0000271 polysaccharide biosynthetic process;GO:0085029 extracellular matrix assembly;GO:0030213 hyaluronan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MY60-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MY67-1", "uniprot_id": "F1MY67_BOVIN", "mass": 28129.0, "length": 246, "protein_name": "Lysosomal-associated transmembrane protein 4B", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Lysosomal-associated transmembrane protein 4B", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for optimal lysosomal function. Blocks EGF-stimulated EGFR intraluminal sorting and degradation. Conversely by binding with the phosphatidylinositol 4,5-bisphosphate, regulates its PIP5K1C interaction, inhibits HGS ubiquitination and relieves LAPTM4B inhibition of EGFR degradation. Recruits SLC3A2 and SLC7A5 (the Leu transporter) to the lysosome, promoting entry of leucine and other essential amino acid (EAA) into the lysosome, stimulating activation of proton-transporting vacuolar (V)-ATPase protein pump (V-ATPase) and hence mTORC1 activation. Plays a role as negative regulator of TGFB1 production in regulatory T cells. Binds ceramide and facilitates its exit from late endosome in order to control cell death pathways., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0042995 cell projection;GO:0032585 multivesicular body membrane", "go_biological_process": "GO:0097213 regulation of lysosomal membrane permeability", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MY67-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MY68-1", "uniprot_id": "F1MY68_BOVIN", "mass": 86754.0, "length": 776, "protein_name": "Interphotoreceptor matrix proteoglycan 1", "gene_name": "IMPG1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IMPG1", "gene_names_refseq": "", "protein_names_uniprotkb": "Interphotoreceptor matrix proteoglycan 1; Sialoprotein associated with cones and rods", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Chondroitin sulfate-, heparin- and hyaluronan-binding protein. May serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0005540 hyaluronic acid binding", "go_cellular_component": "GO:0033165 interphotoreceptor matrix;GO:0001917 photoreceptor inner segment;GO:0001750 photoreceptor outer segment;GO:0140150 gel phase of interstitial matrix", "go_biological_process": "GO:0007601 visual perception", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MY68-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MY70-1", "uniprot_id": "F1MY70_BOVIN", "mass": 34954.0, "length": 313, "protein_name": "Olfactory receptor family 10 subfamily K member 1B", "gene_name": "OR10K1B", "organism": "Bovine", "refseq_name": "olfactory receptor family 10 subfamily K member 1B", "refseq_ac": "NP_001376742", "gene_names_uniprotkb": "OR10K1B", "gene_names_refseq": "OR10K1B", "protein_names_uniprotkb": "Olfactory receptor family 10 subfamily K member 1B", "protein_names_refseq": "olfactory receptor 10K1; olfactory receptor family 10 subfamily K member 1B", "tax_id": 9913, "disease": "", "pathway": " (bta:508806)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Odorant receptor., [UniProtKB, UniProtKB]; Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, 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The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031681 G-protein beta-subunit binding", "go_cellular_component": "GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MYW8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MYY4-1", "uniprot_id": "F1MYY4_BOVIN", "mass": 19492.0, "length": 174, "protein_name": "Interleukin-1", "gene_name": "IL36G", "organism": "Bovine", "refseq_name": "interleukin-36 gamma", "refseq_ac": "XP_002691394", "gene_names_uniprotkb": "IL36G", "gene_names_refseq": "IL36G", "protein_names_uniprotkb": "Interleukin-1", "protein_names_refseq": "interleukin-36 gamma", "tax_id": 9913, "disease": "", "pathway": " (bta:615762); (R-BTA-9014826)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. 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Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival. Activates ENaC (in vitro)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0017080 sodium channel regulator activity;GO:0008236 serine-type peptidase activity", "go_cellular_component": "GO:0043025 neuronal cell body;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0016485 protein processing;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MYZ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MYZ4-1", "uniprot_id": "F1MYZ4_BOVIN", "mass": 92127.0, "length": 828, "protein_name": "Semaphorin-4B", "gene_name": "SEMA4B", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SEMA4B", "gene_names_refseq": "", "protein_names_uniprotkb": "Semaphorin-4B; 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity;GO:0005549 odorant binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0050911 detection of chemical stimulus involved in sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZ20-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZ21-1", "uniprot_id": "F1MZ21_BOVIN", "mass": 90781.0, "length": 802, "protein_name": "Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP", "gene_name": "SART1", "organism": "Bovine", "refseq_name": "U4/U6.U5 tri-snRNP-associated protein 1", "refseq_ac": "NP_001180015", "gene_names_uniprotkb": "SART1", "gene_names_refseq": "SART1", "protein_names_uniprotkb": "Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP", "protein_names_refseq": "SART1, U4/U6.U5 tri-snRNP-associated protein 1; U4/U6.U5 tri-snRNP-associated protein 1; squamous cell carcinoma antigen recognized by T cells; squamous cell carcinoma antigen recognized by T-cells 1", "tax_id": 9913, "disease": "", "pathway": " (bta:615704)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0016607 nuclear speck;GO:0015030 Cajal body;GO:0071013 catalytic step 2 spliceosome;GO:0046540 U4/U6 x U5 tri-snRNP complex", "go_biological_process": "GO:0000481 maturation of 5S rRNA;GO:0045585 positive regulation of cytotoxic T cell differentiation;GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZ21-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZ29-1", "uniprot_id": "F1MZ29_BOVIN", "mass": 35499.0, "length": 314, "protein_name": "Olfactory receptor", "gene_name": "OR6C288", "organism": "Bovine", "refseq_name": "olfactory receptor family 6 subfamily C member 288", "refseq_ac": "NP_001377205", "gene_names_uniprotkb": "OR6C288", "gene_names_refseq": "OR6C288", "protein_names_uniprotkb": "Olfactory receptor", "protein_names_refseq": "olfactory receptor 6C2; olfactory receptor family 6 subfamily C member 288", "tax_id": 9913, "disease": "", "pathway": " (bta:618816)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]., [RefSeq]; Putative odorant or sperm cell receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004984 olfactory receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZS2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T838-1", "uniprot_id": "A0A140T838_BOVIN", "mass": 30702.0, "length": 266, "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IL1B", "gene_names_refseq": "", "protein_names_uniprotkb": "Multifunctional fusion protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-448706); (R-BTA-5620971); (R-BTA-5660668); (R-BTA-9020702); (R-BTA-9960519); (R-BTA-9960525)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding;GO:0019904 protein domain specific binding;GO:0005125 cytokine activity;GO:0005149 interleukin-1 receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol;GO:0005764 lysosome", "go_biological_process": "GO:0070498 interleukin-1-mediated signaling pathway;GO:0060252 positive regulation of glial cell proliferation;GO:0033092 positive regulation of immature T cell proliferation in thymus;GO:0001660 fever generation;GO:1903140 regulation of establishment of endothelial barrier", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T838-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T878-1", "uniprot_id": "A0A140T878_BOVIN", "mass": 89943.0, "length": 787, "protein_name": "Signal transducer and activator of transcription", "gene_name": "STAT5B", "organism": "Bovine", "refseq_name": "signal transducer and activator of transcription 5B", "refseq_ac": "NP_777042", "gene_names_uniprotkb": "STAT5B", "gene_names_refseq": "STAT5B", "protein_names_uniprotkb": "Signal transducer and activator of transcription", "protein_names_refseq": "signal transducer and activator of transcription 5B", "tax_id": 9913, "disease": "", "pathway": " (bta:282376); (R-BTA-1266695); (R-BTA-1433557); (R-BTA-186763); (R-BTA-512988); (R-BTA-8854691); (R-BTA-8983432); (R-BTA-8985947); (R-BTA-9020558); (R-BTA-9020958)", "pathway_count": 10, "publication_count": 3, "publication_id_list": "21435309;24668956;26154111", "class_list": "", "function": "Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation., [UniProtKB, UniProtKB, UniProtKB]; SNPs in JAK2 and STAT5B are associated with mastitis susceptibility in Chinese Holstein cattle, [RefSeq, PubMed]; These results suggested that the SNPs in CD4 and STAT5b may be potential genetic markers for SCS and milk/protein yields selecting and warrant further functional research., [RefSeq, PubMed]; This study suggests that growth hormone inhibits the differentiation of bovine preadipocytes to adipocytes through STAT5b-dependent inhibition of C/EBPalpha and PPARgamma expression., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0035259 nuclear glucocorticoid receptor binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006952 defense response;GO:0040014 regulation of multicellular organism growth;GO:0042127 regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A140T878-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MI90-1", "uniprot_id": "A0A3Q1MI90_BOVIN", "mass": 77126.0, "length": 687, "protein_name": "Protein-glutamine gamma-glutamyltransferase 2", "gene_name": "TGM2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TGM2", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein-glutamine gamma-glutamyltransferase 2; 2.3.2.13; 3.5.1.44; Isopeptidase TGM2; Protein-glutamine deamidase TGM2; Protein-glutamine dopaminyltransferase TGM2; Protein-glutamine histaminyltransferase TGM2; Protein-glutamine noradrenalinyltransferase TGM2; Protein-glutamine serotonyltransferase TGM2; Tissue transglutaminase; Transglutaminase-2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.13;3.5.1.44;3.4.-.-;2.3.1.-", "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0008233 peptidase activity;GO:0003810 protein-glutamine gamma-glutamyltransferase activity;GO:0050568 protein-glutamine glutaminase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005694 chromosome", "go_biological_process": "GO:0006508 proteolysis;GO:0043065 positive regulation of apoptotic process;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0018149 peptide cross-linking;GO:0060348 bone development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MI90-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T8D4-1", "uniprot_id": "A0A140T8D4_BOVIN", "mass": 49236.0, "length": 433, "protein_name": "Legumain", "gene_name": "LGMN", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LGMN", "gene_names_refseq": "", "protein_names_uniprotkb": "Legumain; 3.4.22.34; Protease, cysteine 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1679131); (R-BTA-196791); (R-BTA-2132295)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Also involved in MHC class I antigen presentation in cross-presenting dendritic cells by mediating cleavage and maturation of Perforin-2 (MPEG1), thereby promoting antigen translocation in the cytosol. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.22.34;3.4.22.1;3.4.22.27;3.4.22.38", "go_molecular_function": "GO:0061133 endopeptidase activator activity;GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0045177 apical part of cell;GO:0048471 perinuclear region of cytoplasm;GO:0005770 late endosome;GO:0043202 lysosomal lumen", "go_biological_process": "GO:2001028 positive regulation of endothelial cell chemotaxis;GO:0007613 memory;GO:0008284 positive regulation of cell population proliferation;GO:0008306 associative learning;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8D4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LGG7-1", "uniprot_id": "A0A3Q1LGG7_BOVIN", "mass": 105606.0, "length": 982, "protein_name": "Myocardin", "gene_name": "MYOCD", "organism": "Bovine", "refseq_name": "myocardin isoform X1", "refseq_ac": "XP_002695856", "gene_names_uniprotkb": "MYOCD", "gene_names_refseq": "MYOCD", "protein_names_uniprotkb": "Myocardin", "protein_names_refseq": "myocardin isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:539517)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis, urinary bladder development, and differentiation of the smooth muscle cell lineage (myogenesis). Positively regulates the transcription of genes involved in vascular smooth muscle contraction., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0042826 histone deacetylase binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0070412 R-SMAD binding;GO:0035035 histone acetyltransferase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0035886 vascular associated smooth muscle cell differentiation;GO:0060379 cardiac muscle cell myoblast differentiation;GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045987 positive regulation of smooth muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LGG7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MDJ9-1", "uniprot_id": "A0A3Q1MDJ9_BOVIN", "mass": 92311.0, "length": 850, "protein_name": "CD44 antigen", "gene_name": "CD44", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CD44", "gene_names_refseq": "", "protein_names_uniprotkb": "CD44 antigen; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; Phagocytic glycoprotein I", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1474228); (R-BTA-202733); (R-BTA-2142845); (R-BTA-216083); (R-BTA-2160916); (R-BTA-6798695)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005540 hyaluronic acid binding;GO:0038024 cargo receptor activity;GO:0004896 cytokine receptor activity;GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0005902 microvillus;GO:0032991 protein-containing complex", "go_biological_process": "GO:0048731 system development;GO:0007155 cell adhesion;GO:0042981 regulation of apoptotic process;GO:0009653 anatomical structure morphogenesis;GO:0070374 positive regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MDJ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LI98-1", "uniprot_id": "A0A3Q1LI98_BOVIN", "mass": 124615.0, "length": 1151, "protein_name": "Tyrosine-protein kinase", "gene_name": "ABL1", "organism": "Bovine", "refseq_name": "tyrosine-protein kinase ABL1", "refseq_ac": "NP_001193789", "gene_names_uniprotkb": "ABL1", "gene_names_refseq": "ABL1", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "Abelson murine leukemia viral (v-abl) oncogene homolog 1; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; tyrosine-protein kinase ABL1; v-abl Abelson murine leukemia viral oncogene homolog 1", "tax_id": 9913, "disease": "", "pathway": " (bta:540876); (R-BTA-2029482); (R-BTA-428890); (R-BTA-525793); (R-BTA-5663213); (R-BTA-5685938); (R-BTA-5693565); (R-BTA-69231); (R-BTA-8939236); (R-BTA-9841922); (R-BTA-9860927)", "pathway_count": 11, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.24;2.7.11.1;2.7.11.22;2.7.10.4;3.6.5.2", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0001784 phosphotyrosine residue binding;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0071103 DNA conformation change;GO:1903905 positive regulation of establishment of T cell polarity;GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:0010557 positive regulation of macromolecule biosynthetic process;GO:0006281 DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LI98-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LQ88-1", "uniprot_id": "A0A3Q1LQ88_BOVIN", "mass": 132124.0, "length": 1198, "protein_name": "DAB2 interacting protein", "gene_name": "DAB2IP", "organism": "Bovine", "refseq_name": "disabled homolog 2-interacting protein isoform X7", "refseq_ac": "XP_024854859", "gene_names_uniprotkb": "DAB2IP", "gene_names_refseq": "DAB2IP", "protein_names_uniprotkb": "DAB2 interacting protein", "protein_names_refseq": "disabled homolog 2-interacting protein isoform X7", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, 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"go_biological_process": "GO:1900744 regulation of p38MAPK cascade;GO:0010633 negative regulation of epithelial cell migration;GO:0046580 negative regulation of Ras protein signal transduction;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LQ88-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MHM3-1", "uniprot_id": "A0A3Q1MHM3_BOVIN", "mass": 130263.0, "length": 1197, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "HIPK2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HIPK2", "gene_names_refseq": "", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3899300); (R-BTA-6804756); (R-BTA-8939243); (R-BTA-9022692)", "pathway_count": 4, 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2.7.11.23; 2.7.12.1; Protein kinase minibrain homolog", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1538133)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.10.2;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.10.4;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0004674 protein serine/threonine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0016607 nuclear speck;GO:0030424 axon", "go_biological_process": "GO:0033120 positive regulation of RNA splicing;GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0007623 circadian rhythm;GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LNU2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LP90-1", "uniprot_id": "A0A3Q1LP90_BOVIN", "mass": 115010.0, "length": 1038, "protein_name": "Bone morphogenetic protein receptor type-2", "gene_name": "BMPR2", "organism": "Bovine", "refseq_name": "bone morphogenetic protein receptor type-2 precursor", "refseq_ac": "NP_001291214", "gene_names_uniprotkb": "BMPR2", "gene_names_refseq": "BMPR2; bmprii", "protein_names_uniprotkb": "Bone morphogenetic protein receptor type-2; 2.7.11.30; Bone morphogenetic protein receptor type II", "protein_names_refseq": "bone morphogenetic protein receptor type-2 precursor; bone morphogenetic protein receptor, type II (serine/threonine kinase)", "tax_id": 9913, "disease": "", "pathway": " (bta:407127); (R-BTA-201451)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "21808054;22959639;27221279;29321317;29587293;31389735", "class_list": "", "function": "COMP regulation of BMPR2 appears to have an important role in controlling hypoxia-elicited changes in pulmonary artery superoxide and its potential regulation of contractile phenotype proteins., [RefSeq, PubMed]; Genetic variability is an important component of the number of antral follicles in the bovine ovary., [RefSeq, PubMed]; Inhibition of BMPR2 resulted in increased expression of ALK4 and decreased expression of PTX3, HAS2 and PTGS2., [RefSeq, PubMed]; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Can also mediate signaling through the activation of the p38MAPK cascade. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. Promotes signaling also by binding to activin A/INHBA., [UniProtKB, UniProtKB, UniProtKB]; Stimulation of BMPRII promotes normal pulmonary artery endothelial cell function by activating eNOS., [RefSeq, PubMed]; The miR-17-92 cluster is involved in granulosa cell proliferation and differentiation by coordinately targeting the PTEN and BMPR2 genes., [RefSeq, PubMed]; These findings are important because Wnt, BMPR2, and Akt3 promote neurogenesis and cell survival, processes crucial for lifelong viral latency. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.30;2.3.2.26", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0045296 cadherin binding;GO:0005024 transforming growth factor beta receptor activity;GO:0098821 BMP receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0005912 adherens junction;GO:0009986 cell surface;GO:0014069 postsynaptic density", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048286 lung alveolus development;GO:0001974 blood vessel remodeling;GO:0071363 cellular response to growth factor stimulus;GO:0001568 blood vessel development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A3Q1LP90-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MLT2-1", "uniprot_id": "A0A3Q1MLT2_BOVIN", "mass": 91575.0, "length": 813, "protein_name": "Histone acetyltransferase", "gene_name": "KAT2B", "organism": "Bovine", "refseq_name": "histone acetyltransferase KAT2B isoform X1", "refseq_ac": "XP_024853358", "gene_names_uniprotkb": "KAT2B", "gene_names_refseq": "KAT2B", "protein_names_uniprotkb": "Histone acetyltransferase; 2.3.1.48", "protein_names_refseq": "histone acetyltransferase KAT2B isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:407215); (R-BTA-2032785); (R-BTA-350054); (R-BTA-5250924); (R-BTA-5689901); (R-BTA-8936459); (R-BTA-8941856); (R-BTA-9018519); (R-BTA-9617629); (R-BTA-9772755)", "pathway_count": 10, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.48;3.6.4.13;2.1.1.319;2.1.1.364;2.3.1.-;2.7.10.2;2.7.7.6;2.3.1.259", "go_molecular_function": "GO:0043992 histone H3K9 acetyltransferase activity;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0008047 enzyme activator activity;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0031674 I band", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MLT2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MDA4-1", "uniprot_id": "A0A3Q1MDA4_BOVIN", "mass": 121761.0, "length": 1121, "protein_name": "Dystroglycan 1", "gene_name": "DAG1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DAG1", "gene_names_refseq": "", "protein_names_uniprotkb": "Dystroglycan 1; Dystroglycan; Dystrophin-associated glycoprotein 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-8932504); (R-BTA-8932505); (R-BTA-8932506); (R-BTA-9010553); (R-BTA-9913351); (R-BTA-9939291)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The dystroglycan complex is involved in a number of signaling events and processes including laminin deposition and extracellular matrix assembly, acetylcholine receptor clustering, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, epithelial polarization, and epithelium branching morphogenesis. Required for the formation of photoreceptor ribbon synapses, and long-term maintenance of inhibitory synapses in cerebellar Purkinje cells. Also involved in the positive regulation of cartilage formation through agrin (AGRN) binding and up-regulation of SOX9, a transcription factor that plays a key role in chondrocytes differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0003779 actin binding;GO:0042802 identical protein binding;GO:0043395 heparan sulfate proteoglycan binding;GO:0051393 alpha-actinin binding", "go_cellular_component": "GO:0016010 dystrophin-associated glycoprotein complex;GO:0005576 extracellular region;GO:0005654 nucleoplasm;GO:0005856 cytoskeleton;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0098942 retrograde trans-synaptic signaling by trans-synaptic protein complex;GO:0085029 extracellular matrix assembly;GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering;GO:0006509 membrane protein ectodomain proteolysis;GO:0051124 synaptic assembly at neuromuscular junction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MDA4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LRR9-1", "uniprot_id": "A0A3Q1LRR9_BOVIN", "mass": 97324.0, "length": 895, "protein_name": "Tyrosine-protein kinase receptor TYRO3", "gene_name": "TYRO3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TYRO3", "gene_names_refseq": "", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor TYRO3; 2.7.10.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:788224)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.1;2.7.10.4", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0001618 virus receptor activity;GO:0004714 transmembrane receptor protein tyrosine kinase activity;GO:0043548 phosphatidylinositol 3-kinase binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0043235 receptor complex", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007399 nervous system development;GO:0016477 cell migration;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0070050 neuron cellular homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LRR9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LTC7-1", "uniprot_id": "A0A3Q1LTC7_BOVIN", "mass": 90969.0, "length": 820, "protein_name": "Fragile X messenger ribonucleoprotein 1", "gene_name": "FMR1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FMR1", "gene_names_refseq": "", "protein_names_uniprotkb": "Fragile X messenger ribonucleoprotein 1; Fragile X messenger ribonucleoprotein; Protein FMR-1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0030371 translation repressor activity;GO:0035198 miRNA binding;GO:0003730 mRNA 3'-UTR binding;GO:1990247 N6-methyladenosine-containing RNA reader activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005829 cytosol;GO:0030426 growth cone;GO:0043197 dendritic spine;GO:0043204 perikaryon", "go_biological_process": "GO:0006281 DNA repair;GO:0006397 mRNA processing;GO:0006406 mRNA export from nucleus;GO:0007399 nervous system development;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LTC7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MLQ6-1", "uniprot_id": "A0A3Q1MLQ6_BOVIN", "mass": 85009.0, "length": 752, "protein_name": "Amyloid-beta A4 protein", "gene_name": "APP", "organism": "Bovine", "refseq_name": "amyloid-beta precursor protein isoform X2", "refseq_ac": "XP_005201195", "gene_names_uniprotkb": "APP", "gene_names_refseq": "APP", "protein_names_uniprotkb": "Amyloid-beta A4 protein", "protein_names_refseq": "amyloid-beta precursor protein isoform X2", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-114608); (R-BTA-3000178); (R-BTA-381426); (R-BTA-416476); (R-BTA-432720); (R-BTA-445989); (R-BTA-879415); (R-BTA-8957275); (R-BTA-933542); (R-BTA-9609523); (R-BTA-9769739); (R-BTA-9837999)", "pathway_count": 12, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity;GO:0005102 signaling receptor binding;GO:0008201 heparin binding;GO:0030546 signaling receptor activator activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0099503 secretory vesicle;GO:0005615 extracellular space;GO:0005641 nuclear envelope lumen;GO:0005769 early endosome;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0032224 positive regulation of synaptic transmission, cholinergic;GO:0001774 microglial cell activation;GO:0002265 astrocyte activation involved in immune response;GO:0006897 endocytosis;GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MLQ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LUY1-1", "uniprot_id": "A0A3Q1LUY1_BOVIN", "mass": 172786.0, "length": 1603, "protein_name": "Protein scribble homolog", "gene_name": "SCRIB", "organism": "Bovine", "refseq_name": "protein scribble homolog isoform X1", "refseq_ac": "XP_024857692", "gene_names_uniprotkb": "SCRIB", "gene_names_refseq": "SCRIB", "protein_names_uniprotkb": "Protein scribble homolog", "protein_names_refseq": "protein scribble homolog isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:100295316); (R-BTA-9013406); (R-BTA-9696264); (R-BTA-9696270)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0035748 myelin sheath abaxonal region;GO:0005654 nucleoplasm;GO:0005912 adherens junction;GO:0014069 postsynaptic density;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0060603 mammary gland duct morphogenesis;GO:0016080 synaptic vesicle targeting;GO:0035089 establishment of apical/basal cell polarity;GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0008283 cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LUY1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LV96-1", "uniprot_id": "A0A3Q1LV96_BOVIN", "mass": 162417.0, "length": 1461, "protein_name": "Phospholipase B1, membrane-associated", "gene_name": "PLB1", "organism": "Bovine", "refseq_name": "phospholipase B1, membrane-associated", "refseq_ac": "XP_015329047", "gene_names_uniprotkb": "PLB1", "gene_names_refseq": "PLB1", "protein_names_uniprotkb": "Phospholipase B1, membrane-associated; 3.1.1.3; 3.1.1.4; 3.1.1.5; Lysophospholipase; Phospholipase A2; Phospholipase B/lipase; Triacylglycerol lipase", "protein_names_refseq": "phospholipase B1, membrane-associated", "tax_id": 9913, "disease": "", "pathway": " (bta:506508)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Calcium-independent membrane-associated phospholipase that catalyzes complete diacylation of phospholipids by hydrolyzing both sn-1 and sn-2 fatty acyl chains attached to the glycerol backbone (phospholipase B activity). Has dual phospholipase and lysophospholipase activities toward diacylphospholipids. Preferentially cleaves sn-2 ester bonds over sn-1 bonds. Acts as a lipase toward glycerolipid substrates. Hydrolyzes fatty acyl chains of diacylglycerols with preference for the sn-2 position and of triacylglycerols with not positional selectivity. May also hydrolyze long chain retinyl esters such as retinyl palmitate. May contribute to digestion of dietary phospholipids, glycerolipids and retinoids, facilitating lipid absorption at the brush border., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.1.4;3.1.1.32;3.1.1.3;3.1.1.5;3.1.2.22;3.1.1.23;3.1.1.79;2.3.1.51;1.11.1.27;3.1.1.26;3.1.2.2;3.5.1.1;3.1.1.47;3.1.1.116;2.3.1.23;3.1.1.34;3.1.1.13;3.1.1.6;2.3.1.149;3.1.1.-;3.1.-.-;3.1.2.-;2.3.1.-", "go_molecular_function": "GO:0004622 phosphatidylcholine lysophospholipase activity;GO:0004623 phospholipase A2 activity;GO:0004806 triacylglycerol lipase activity", "go_cellular_component": "GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LV96-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LVP1-1", "uniprot_id": "A0A3Q1LVP1_BOVIN", "mass": 115645.0, "length": 1009, "protein_name": "Protein-tyrosine kinase 2-beta", "gene_name": "PTK2B", "organism": "Bovine", "refseq_name": "protein-tyrosine kinase 2-beta isoform X1", "refseq_ac": "XP_059745200", "gene_names_uniprotkb": "PTK2B", "gene_names_refseq": "PTK2B; PYK2", "protein_names_uniprotkb": "Protein-tyrosine kinase 2-beta; 2.7.10.2; Calcium-dependent tyrosine kinase; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; Focal adhesion kinase 2; Proline-rich tyrosine kinase 2", "protein_names_refseq": "protein-tyrosine kinase 2-beta isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-391160); (R-BTA-4420097); (R-BTA-9013420); (R-BTA-9020558)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;2.7.11.1;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;3.4.19.12;3.6.5.2;2.7.10.4;3.6.4.10", "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005925 focal adhesion", "go_biological_process": "GO:0086100 endothelin receptor signaling pathway;GO:0007229 integrin-mediated signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0008285 negative regulation of cell population proliferation;GO:0010976 positive regulation of neuron projection development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LVP1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LWJ7-1", "uniprot_id": "A0A3Q1LWJ7_BOVIN", "mass": 53869.0, "length": 480, "protein_name": "Steroid 17-alpha-hydroxylase/17,20 lyase", "gene_name": "LOC132342070", "organism": "Bovine", "refseq_name": "steroid 17-alpha-hydroxylase/17,20 lyase isoform X2", "refseq_ac": "XP_024841234", "gene_names_uniprotkb": "LOC132342070", "gene_names_refseq": "LOC132342070", "protein_names_uniprotkb": "Steroid 17-alpha-hydroxylase/17,20 lyase; 1.14.14.19; 1.14.14.32; 17-alpha-hydroxyprogesterone aldolase; CYPXVII; Cytochrome P450 17A1; Cytochrome P450-C17; Steroid 17-alpha-monooxygenase", "protein_names_refseq": "steroid 17-alpha-hydroxylase/17,20 lyase isoform X2", "tax_id": 9913, "disease": "", "pathway": " (bta:132342070); (R-BTA-193048); (R-BTA-194002)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.14.19;1.14.14.32;1.14.14.25;1.14.14.1", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016829 lyase activity;GO:0004508 steroid 17-alpha-monooxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006694 steroid biosynthetic process;GO:0042446 hormone biosynthetic process;GO:0042448 progesterone metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LWJ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NEF8-1", "uniprot_id": "A0A3Q1NEF8_BOVIN", "mass": 29174.0, "length": 262, "protein_name": "small monomeric GTPase", "gene_name": "RAC1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RAC1", "gene_names_refseq": "", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0005525 GTP binding;GO:0003925 G protein activity;GO:0019901 protein kinase binding;GO:0031996 thioesterase binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0043020 NADPH oxidase complex;GO:0098978 glutamatergic synapse;GO:0001891 phagocytic cup;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction;GO:0010764 negative regulation of fibroblast migration;GO:2000386 positive regulation of ovarian follicle development;GO:0046425 regulation of receptor signaling pathway via JAK-STAT;GO:0003376 sphingosine-1-phosphate receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NEF8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPK0-1", "uniprot_id": "A0A3S5ZPK0_BOVIN", "mass": 116967.0, "length": 1046, "protein_name": "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit", "gene_name": "OGT", "organism": "Bovine", "refseq_name": "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1", "refseq_ac": "XP_005228084", "gene_names_uniprotkb": "OGT", "gene_names_refseq": "OGT", "protein_names_uniprotkb": "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; 2.4.1.255; O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine transferase 110 kDa subunit", "protein_names_refseq": "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3214847); (R-BTA-5675482); (R-BTA-5689603); (R-BTA-9772755)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.255;2.3.1.48;3.4.19.12", "go_molecular_function": "GO:0097363 protein O-acetylglucosaminyltransferase activity;GO:0008289 lipid binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0098978 glutamatergic synapse;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0048511 rhythmic process;GO:0006325 chromatin organization;GO:1904263 positive regulation of TORC1 signaling;GO:0006110 regulation of glycolytic process", "synthesized_glycan_count": 5, "hit_score": 0.1, "record_id": "A0A3S5ZPK0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M0Z8-1", "uniprot_id": "A0A3Q1M0Z8_BOVIN", "mass": 46421.0, "length": 426, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "SMAD7", "organism": "Bovine", "refseq_name": "mothers against decapentaplegic homolog 7 isoform X1", "refseq_ac": "XP_005224288", "gene_names_uniprotkb": "SMAD7", "gene_names_refseq": "SMAD7", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "mothers against decapentaplegic homolog 7 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-201451); (R-BTA-2173788); (R-BTA-2173796); (R-BTA-5689880)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0003714 transcription corepressor activity;GO:0031625 ubiquitin protein ligase binding;GO:0005518 collagen binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005912 adherens junction", "go_biological_process": "GO:0010717 regulation of epithelial to mesenchymal transition;GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization;GO:0002725 negative regulation of T cell cytokine production;GO:2000320 negative regulation of T-helper 17 cell differentiation;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M0Z8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M155-1", "uniprot_id": "A0A3Q1M155_BOVIN", "mass": 69148.0, "length": 614, "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "DDX5", "organism": "Bovine", "refseq_name": "probable ATP-dependent RNA helicase DDX5", "refseq_ac": "NP_001178324", "gene_names_uniprotkb": "DDX5", "gene_names_refseq": "DDX5", "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase DDX5; 3.6.4.13; DEAD box protein 5", "protein_names_refseq": "DEAD (Asp-Glu-Ala-Asp) box helicase 5; DEAD (Asp-Glu-Ala-Asp) box polypeptide 5; probable ATP-dependent RNA helicase DDX5", "tax_id": 9913, "disease": "", "pathway": " (bta:533700); (R-BTA-3899300); (R-BTA-72163); (R-BTA-9018519); (R-BTA-9770562)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;2.3.1.48;2.7.7.52;2.7.7.19;3.6.4.6;2.1.1.319;5.2.1.8;3.6.4.10;5.6.2.3;3.6.5.-;2.7.1.78;5.6.2.-;2.7.4.3;3.6.4.-;3.1.13.-;2.7.7.48;2.7.7.6;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;3.1.27.-;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.3.53;3.1.3.16;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0036002 pre-mRNA binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0043021 ribonucleoprotein complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0030509 BMP signaling pathway;GO:0048511 rhythmic process;GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M155-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MST2-1", "uniprot_id": "A0A3Q1MST2_BOVIN", "mass": 120912.0, "length": 1146, "protein_name": "Sterol regulatory element-binding protein 1", "gene_name": "SREBF1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SREBF1", "gene_names_refseq": "", "protein_names_uniprotkb": "Sterol regulatory element-binding protein 1; 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Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'). Regulates the promoters of genes involved in cholesterol biosynthesis and the LDL receptor (LDLR) pathway of sterol regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Precursor of the transcription factor form (Processed sterol regulatory element-binding protein 1), which is embedded in the endoplasmic reticulum membrane. Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis and lipid homeostasis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0046983 protein dimerization activity;GO:0003682 chromatin binding;GO:0019901 protein kinase binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005789 endoplasmic reticulum membrane;GO:0012507 ER to Golgi transport vesicle membrane;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0008203 cholesterol metabolic process;GO:0008610 lipid biosynthetic process;GO:0045542 positive regulation of cholesterol biosynthetic process;GO:0007623 circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MST2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M2R1-1", "uniprot_id": "A0A3Q1M2R1_BOVIN", "mass": 124685.0, "length": 1124, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "RC3H1", "organism": "Bovine", "refseq_name": "roquin-1 isoform X3", "refseq_ac": "XP_024832627", "gene_names_uniprotkb": "RC3H1", "gene_names_refseq": "RC3H1", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "roquin-1 isoform X3", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0003725 double-stranded RNA binding;GO:0035198 miRNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0000932 P-body;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0002635 negative regulation of germinal center formation;GO:2000320 negative regulation of T-helper 17 cell differentiation;GO:0050852 T cell receptor signaling pathway;GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M2R1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M3Q3-1", "uniprot_id": "A0A3Q1M3Q3_BOVIN", "mass": 22489.0, "length": 194, "protein_name": "Fibroblast growth factor", "gene_name": "FGF7", "organism": "Bovine", "refseq_name": "fibroblast growth factor 7 precursor", "refseq_ac": "NP_001180060", "gene_names_uniprotkb": "FGF7", "gene_names_refseq": "FGF5B; FGF7", "protein_names_uniprotkb": "Fibroblast growth factor; FGF", "protein_names_refseq": "fibroblast growth factor 5B; fibroblast growth factor 7 (keratinocyte growth factor); fibroblast growth factor 7 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:616885); (R-BTA-109704); (R-BTA-1257604); (R-BTA-190377); (R-BTA-5654221); (R-BTA-5654695); (R-BTA-5654699); (R-BTA-5654700); (R-BTA-5654727); (R-BTA-5673001); (R-BTA-6811558)", "pathway_count": 11, "publication_count": 2, "publication_id_list": "16415522;18386286", "class_list": "", "function": "FGF1 and FGF7 may be involved differently in the process of follicle maturation and CL formation, which is strongly dependent on angiogenesis, [RefSeq, PubMed]; FGF7 may be an important regulator for oocyte growth and its action is mediated via the KIT/KITLG signaling pathway., [RefSeq, PubMed]; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0042056 chemoattractant activity;GO:0008083 growth factor activity;GO:0005111 type 2 fibroblast growth factor receptor binding", "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0098794 postsynapse", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade;GO:0030324 lung development;GO:0030036 actin cytoskeleton organization;GO:0051549 positive regulation of keratinocyte migration;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A0A3Q1M3Q3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M4M7-1", "uniprot_id": "A0A3Q1M4M7_BOVIN", "mass": 143555.0, "length": 1283, "protein_name": "BCR activator of RhoGEF and GTPase", "gene_name": "BCR", "organism": "Bovine", "refseq_name": "breakpoint cluster region protein isoform X1", "refseq_ac": "XP_024833625", "gene_names_uniprotkb": "BCR", "gene_names_refseq": "BCR", "protein_names_uniprotkb": "BCR activator of RhoGEF and GTPase", "protein_names_refseq": "breakpoint cluster region protein isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:789892); (R-BTA-8980692); (R-BTA-9013106); (R-BTA-9013148); (R-BTA-9013404); (R-BTA-9013423)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005096 GTPase activator activity;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0014069 postsynaptic density;GO:0016020 membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0002692 negative regulation of cellular extravasation;GO:0043114 regulation of vascular permeability;GO:0060313 negative regulation of blood vessel remodeling;GO:0050804 modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M4M7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M5A0-1", "uniprot_id": "A0A3Q1M5A0_BOVIN", "mass": 72806.0, "length": 650, "protein_name": "RNA-binding protein FXR1", "gene_name": "FXR1", "organism": "Bovine", "refseq_name": "RNA-binding protein FXR1 isoform X3", "refseq_ac": "XP_005201658", "gene_names_uniprotkb": "FXR1", "gene_names_refseq": "FXR1", "protein_names_uniprotkb": "RNA-binding protein FXR1", "protein_names_refseq": "RNA-binding protein FXR1 isoform X3", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0043021 ribonucleoprotein complex binding;GO:0046982 protein heterodimerization activity;GO:0003730 mRNA 3'-UTR binding;GO:0045182 translation regulator activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005829 cytosol;GO:0030424 axon", "go_biological_process": "GO:0060538 skeletal muscle organ development;GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:1900272 negative regulation of long-term synaptic potentiation;GO:0032720 negative regulation of tumor necrosis factor production;GO:0043488 regulation of mRNA stability", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M5A0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M5F4-1", "uniprot_id": "A0A3Q1M5F4_BOVIN", "mass": 96498.0, "length": 890, "protein_name": "Androgen receptor", "gene_name": "AR", "organism": "Bovine", "refseq_name": "androgen receptor", "refseq_ac": "NP_001231056", "gene_names_uniprotkb": "AR", "gene_names_refseq": "AR", "protein_names_uniprotkb": "Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4", "protein_names_refseq": "androgen receptor", "tax_id": 9913, "disease": "", "pathway": " (bta:280675); (R-BTA-3371497); (R-BTA-383280); (R-BTA-4090294); (R-BTA-5625886); (R-BTA-5689880); (R-BTA-8940973)", "pathway_count": 7, "publication_count": 4, "publication_id_list": "14585317;16641147;18403176;23481223", "class_list": "", "function": "FSHR is specifically regulated through androgen receptor in granulosa cells, [RefSeq, PubMed]; No association between the AR CAG polymorphism and the relative risk of prostate cancer in white Brazilian individuals with a CAG repeat, [RefSeq, PubMed]; Roles of IGF-I and the estrogen, androgen and IGF-I receptors in estradiol-17beta- and trenbolone acetate-stimulated proliferation of cultured bovine satellite cells., [RefSeq, PubMed]; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3., [UniProtKB, UniProtKB]; Substantial up-regulation of androgen receptor expression during trophoblast giant cell differentiation suggests that androgens may be related to this process and are active products of bovine placental steroidogenesis, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0005102 signaling receptor binding;GO:0008270 zinc ion binding;GO:0051117 ATPase binding;GO:0003707 nuclear steroid receptor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0016607 nuclear speck;GO:0000785 chromatin;GO:0032991 protein-containing complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0008284 positive regulation of cell population proliferation;GO:0008285 negative regulation of cell population proliferation;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A3Q1M5F4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M5V8-1", "uniprot_id": "A0A3Q1M5V8_BOVIN", "mass": 44735.0, "length": 398, "protein_name": "Adenosine deaminase", "gene_name": "ADA", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ADA", "gene_names_refseq": "", "protein_names_uniprotkb": "Adenosine deaminase; 3.5.4.4; Adenosine aminohydrolase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-74217); (R-BTA-9755088)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.4.4;2.4.2.1;2.4.2.28", "go_molecular_function": "GO:0004000 adenosine deaminase activity;GO:0046872 metal ion binding;GO:0008270 zinc ion binding;GO:0046936 2'-deoxyadenosine deaminase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005764 lysosome;GO:0009897 external side of plasma membrane;GO:0060205 cytoplasmic vesicle lumen;GO:0070161 anchoring junction", "go_biological_process": "GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:0006154 adenosine catabolic process;GO:0009117 nucleotide metabolic process;GO:0046103 inosine biosynthetic process;GO:0042110 T cell activation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M5V8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M6K1-1", "uniprot_id": "A0A3Q1M6K1_BOVIN", "mass": 151510.0, "length": 1386, "protein_name": "Receptor-type tyrosine-protein phosphatase eta", "gene_name": "PTPRJ", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PTPRJ", "gene_names_refseq": "", "protein_names_uniprotkb": "Receptor-type tyrosine-protein phosphatase eta; 3.1.3.48; Protein-tyrosine phosphatase receptor type J", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-202427); (R-BTA-6798695); (R-BTA-6807004); (R-BTA-9706369)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.4.4;3.1.3.48;3.1.3.16;7.6.2.1;3.6.5.2;3.1.3.2;2.3.1.51;3.1.3.67;3.1.3.21;1.14.14.18;3.1.3.5;3.2.2.6;6.2.1.3;2.7.10.1;1.6.3.-;3.4.21.73;2.7.10.2;2.7.10.4;3.4.24.81;1.2.1.5;1.2.1.28;1.2.1.7;1.2.1.48;1.1.1.-;3.1.3.18;1.14.19.17;5.2.1.-", "go_molecular_function": "GO:0005161 platelet-derived growth factor receptor binding;GO:0042802 identical protein binding;GO:0051019 mitogen-activated protein kinase binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005911 cell-cell junction;GO:0009986 cell surface;GO:0032587 ruffle membrane;GO:0001772 immunological synapse;GO:0016020 membrane", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0007165 signal transduction;GO:0008285 negative regulation of cell population proliferation;GO:0043410 positive regulation of MAPK cascade;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M6K1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZP79-1", "uniprot_id": "A0A3S5ZP79_BOVIN", "mass": 55961.0, "length": 492, "protein_name": "Cytochrome P450 2E1", "gene_name": "CYP2C87", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CYP2C87", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome P450 2E1; 1.14.13.n7; 1.14.14.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-211981); (R-BTA-211999); (R-BTA-2142670); (R-BTA-2142816); (R-BTA-9027307); (R-BTA-9749641)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics., [UniProtKB, UniProtKB, UniProtKB]; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.14.-;1.14.14.1;1.14.13.n7", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0051879 Hsp90 protein binding;GO:0030544 Hsp70 protein binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005737 cytoplasm;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0042178 xenobiotic catabolic process;GO:0019373 epoxygenase P450 pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZP79-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MAT2-1", "uniprot_id": "A0A3Q1MAT2_BOVIN", "mass": 58337.0, "length": 524, "protein_name": "Alpha-1A adrenergic receptor", "gene_name": "ADRA1A", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ADRA1A", "gene_names_refseq": "", "protein_names_uniprotkb": "Alpha-1A adrenergic receptor; Alpha-1A adrenoreceptor; Alpha-1C adrenergic receptor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-390696); (R-BTA-416476); (R-BTA-416482)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Alpha-1 adrenergic receptors are G protein-coupled receptors for catecholamines that signal through the G(q) family of G proteins, including G(q) and G(11). Upon activation, they stimulate the phosphatidylinositol-calcium second messenger pathway, leading to calcium release from intracellular stores and activation of protein kinase C. ADRA1A binds the catecholamine ligands norepinephrine and epinephrine. Can also couple to G(14) protein. Nuclear ADRA1A forms heterooligomers with ADRA1B to regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes. At the plasma membrane, ADRA1A interacts with CAVIN4/MURC to regulates ERK activation in cardiomyocytes, contributing to the regulation of cardiac hypertrophy. Additionally, functions as a vasopressor in resistance arteries and plays a role in maintaining normal arterial blood pressure., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004937 alpha1-adrenergic receptor activity;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031965 nuclear membrane;GO:0005901 caveola;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0019229 regulation of vasoconstriction;GO:0055117 regulation of cardiac muscle contraction;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0007267 cell-cell signaling;GO:0043410 positive regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MAT2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M899-1", "uniprot_id": "A0A3Q1M899_BOVIN", "mass": 47212.0, "length": 421, "protein_name": "Acyl-coenzyme A diphosphatase NUDT19", "gene_name": "NUDT19", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NUDT19", "gene_names_refseq": "", "protein_names_uniprotkb": "Acyl-coenzyme A diphosphatase NUDT19; 3.6.1.77; Nucleoside diphosphate-linked moiety X motif 19", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters and at low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates. Highest activity seen with medium-chain acyl-CoA esters and higher rates of activity seen with the unsaturated acyl-CoA esters compared with the saturated esters. Exhibits decapping activity towards dpCoA-capped RNAs in vitro., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.1.77;3.6.1.9;3.6.1.68;3.6.1.76;3.6.1.17;3.6.1.62;3.6.1.64;3.6.1.-", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0010945 coenzyme A diphosphatase activity;GO:0046872 metal ion binding", "go_cellular_component": "", "go_biological_process": "GO:0036114 medium-chain fatty-acyl-CoA catabolic process;GO:2001294 malonyl-CoA catabolic process;GO:0015938 coenzyme A catabolic process;GO:0044580 butyryl-CoA catabolic process;GO:1901289 succinyl-CoA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M899-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MLE6-1", "uniprot_id": "A0A3Q1MLE6_BOVIN", "mass": 114550.0, "length": 1042, "protein_name": "Hormone-sensitive lipase", "gene_name": "LIPE", "organism": "Bovine", "refseq_name": "hormone-sensitive lipase isoform X1", "refseq_ac": "XP_024833729", "gene_names_uniprotkb": "LIPE", "gene_names_refseq": "LIPE; REH; hsl", "protein_names_uniprotkb": "Hormone-sensitive lipase; 3.1.1.23; 3.1.1.79; Monoacylglycerol lipase LIPE; Retinyl ester hydrolase", "protein_names_refseq": "hormone-sensitive lipase isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Lipase with broad substrate specificity, catalyzing the hydrolysis of triacylglycerols (TAGs), diacylglycerols (DAGs), monoacylglycerols (MAGs), cholesteryl esters and retinyl esters. Shows a preferential hydrolysis of DAGs over TAGs and MAGs. Preferentially hydrolyzes fatty acid (FA) esters at the sn-3 position of the glycerol backbone in DAGs and FA esters at the sn-1 and sn-2 positions of the glycerol backbone in TAGs. Catalyzes the hydrolysis of 2-arachidonoylglycerol, an endocannabinoid and of 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.1.32;3.1.1.3;3.1.1.4;3.1.1.5;3.1.1.23;3.1.1.79;2.3.1.51;3.5.1.99;3.1.1.26;2.3.1.20;3.1.1.116;3.1.1.34;3.1.1.13;3.1.1.6;3.1.1.-;3.1.-.-;3.1.1.71;2.3.1.76", "go_molecular_function": "GO:0004771 sterol ester esterase activity;GO:0047372 monoacylglycerol lipase activity;GO:0004806 triacylglycerol lipase activity;GO:0050253 retinyl-palmitate esterase activity;GO:0120516 diacylglycerol lipase activity", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005829 cytosol;GO:0005901 caveola", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0019433 triglyceride catabolic process;GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MLE6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M8R6-1", "uniprot_id": "A0A3Q1M8R6_BOVIN", "mass": 96605.0, "length": 871, "protein_name": "Protein PML", "gene_name": "PML", "organism": "Bovine", "refseq_name": "protein PML isoform X1", "refseq_ac": "XP_005221963", "gene_names_uniprotkb": "PML", "gene_names_refseq": "PML", "protein_names_uniprotkb": "Protein PML", "protein_names_refseq": "protein PML isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:100138545); (R-BTA-3108214); (R-BTA-3232142); (R-BTA-6804758); (R-BTA-8934593); (R-BTA-8948747)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0031625 ubiquitin protein ligase binding;GO:0046332 SMAD binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0044790 suppression of viral release by host;GO:0030578 PML body organization;GO:0006351 DNA-templated transcription;GO:0008285 negative regulation of cell population proliferation;GO:0030155 regulation of cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M8R6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MEG8-1", "uniprot_id": "A0A3Q1MEG8_BOVIN", "mass": 30326.0, "length": 268, "protein_name": "Ia antigen-associated invariant chain", "gene_name": "CD74", "organism": "Bovine", "refseq_name": "HLA class II histocompatibility antigen gamma chain isoform X1", "refseq_ac": "XP_005209667", "gene_names_uniprotkb": "CD74", "gene_names_refseq": "CD74", "protein_names_uniprotkb": "Ia antigen-associated invariant chain", "protein_names_refseq": "HLA class II histocompatibility antigen gamma chain isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-202733); (R-BTA-2132295)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds to the peptide-binding site of MHC class II alpha/beta heterodimers forming an alpha-beta-CLIP complex, thereby preventing the loading of antigenic peptides to the MHC class II complex until its release by HLA-DM in the endosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035718 macrophage migration inhibitory factor binding;GO:0001540 amyloid-beta binding;GO:0042609 CD4 receptor binding;GO:0050998 nitric-oxide synthase binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0009986 cell surface", "go_biological_process": "GO:0001961 positive regulation of cytokine-mediated signaling pathway;GO:0006886 intracellular protein transport;GO:0070206 protein trimerization;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0030336 negative regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MEG8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MET8-1", "uniprot_id": "A0A3Q1MET8_BOVIN", "mass": 54753.0, "length": 495, "protein_name": "Ribitol-5-phosphate transferase", "gene_name": "FKRP", "organism": "Bovine", "refseq_name": "ribitol 5-phosphate transferase FKRP", "refseq_ac": "NP_001093184", "gene_names_uniprotkb": "FKRP", "gene_names_refseq": "FKRP", "protein_names_uniprotkb": "Ribitol-5-phosphate transferase", "protein_names_refseq": "ribitol 5-phosphate transferase FKRP", "tax_id": 9913, "disease": "", "pathway": " (bta:539701); (R-BTA-9939291)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0043236 laminin binding;GO:0002162 dystroglycan binding;GO:0016780 phosphotransferase activity, for other substituted phosphate groups", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005615 extracellular space;GO:0005791 rough endoplasmic reticulum;GO:0042383 sarcolemma;GO:0098723 skeletal muscle myofibril", "go_biological_process": "GO:0051262 protein tetramerization;GO:0035269 protein O-linked glycosylation via mannose", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MET8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MFK2-1", "uniprot_id": "A0A3Q1MFK2_BOVIN", "mass": 109573.0, "length": 965, "protein_name": "Vacuolar protein sorting-associated protein 54", "gene_name": "VPS54", "organism": "Bovine", "refseq_name": "vacuolar protein sorting-associated protein 54 isoform X2", "refseq_ac": "XP_005212869", "gene_names_uniprotkb": "VPS54", "gene_names_refseq": "VPS54", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 54", "protein_names_refseq": "vacuolar protein sorting-associated protein 54 isoform X2", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Within the GARP complex, required to tether the complex to the TGN. Not involved in endocytic recycling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000938 GARP complex;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0016020 membrane;GO:0045202 synapse", "go_biological_process": "GO:0048708 astrocyte differentiation;GO:0010992 ubiquitin recycling;GO:0071393 cellular response to progesterone stimulus;GO:0030149 sphingolipid catabolic process;GO:0001701 in utero embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MFK2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MHB0-1", "uniprot_id": "A0A3Q1MHB0_BOVIN", "mass": 134065.0, "length": 1209, "protein_name": "Receptor protein-tyrosine kinase", "gene_name": "EGFR", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "EGFR", "gene_names_refseq": "", "protein_names_uniprotkb": "Receptor protein-tyrosine kinase; 2.7.10.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1257604); (R-BTA-177929); (R-BTA-179812); (R-BTA-180292); (R-BTA-180336); (R-BTA-182971); (R-BTA-212718); (R-BTA-2179392); (R-BTA-5673001); (R-BTA-6811558); (R-BTA-8856825); (R-BTA-8856828); (R-BTA-8857538); (R-BTA-9009391)", "pathway_count": 14, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;3.6.5.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;3.6.5.5;2.7.11.1;2.3.2.27;3.1.3.48;2.7.1.153;2.7.1.137;2.7.1.154;5.6.1.6;3.1.3.36;3.6.4.10;3.6.4.-;2.7.10.4;2.7.11.17", "go_molecular_function": "GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0051015 actin filament binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0016323 basolateral plasma membrane;GO:0030054 cell junction", "go_biological_process": "GO:0030307 positive regulation of cell growth;GO:0030335 positive regulation of cell migration;GO:0043066 negative regulation of apoptotic process;GO:0043410 positive regulation of MAPK cascade;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MHB0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MHG9-1", "uniprot_id": "A0A3Q1MHG9_BOVIN", "mass": 71679.0, "length": 628, "protein_name": "Tyrosine-protein kinase", "gene_name": "SYK", "organism": "Bovine", "refseq_name": "tyrosine-protein kinase SYK isoform X1", "refseq_ac": "XP_005210492", "gene_names_uniprotkb": "SYK", "gene_names_refseq": "SYK", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "tyrosine-protein kinase SYK isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-114604); (R-BTA-2029482); (R-BTA-2029485); (R-BTA-2424491); (R-BTA-2454202); (R-BTA-2730905); (R-BTA-2871796); (R-BTA-2871809); (R-BTA-354192); (R-BTA-5621480); (R-BTA-9020558); (R-BTA-912631); (R-BTA-9674555); (R-BTA-9705462); (R-BTA-9706374); (R-BTA-983695)", "pathway_count": 16, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;3.6.5.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.1;2.3.2.27;3.1.4.11;2.7.1.153;2.7.1.137;3.1.3.48;2.7.10.4;2.3.2.24;2.3.2.23", "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005178 integrin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0042101 T cell receptor complex;GO:0032009 early phagosome", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0002283 neutrophil activation involved in immune response;GO:0002554 serotonin secretion by platelet;GO:0038156 interleukin-3-mediated signaling pathway;GO:0007229 integrin-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MHG9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MJR6-1", "uniprot_id": "A0A3Q1MJR6_BOVIN", "mass": 39119.0, "length": 351, "protein_name": "Protein Wnt", "gene_name": "WNT4", "organism": "Bovine", "refseq_name": "protein Wnt-4 isoform X1", "refseq_ac": "XP_024838518", "gene_names_uniprotkb": "WNT4", "gene_names_refseq": "WNT4", "protein_names_uniprotkb": "Protein Wnt", "protein_names_refseq": "protein Wnt-4 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:789600); (R-BTA-3238698); (R-BTA-4086400)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ligand for members of the frizzled family of seven transmembrane receptors., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005109 frizzled binding;GO:0003714 transcription corepressor activity;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0009986 cell surface;GO:0031012 extracellular matrix", "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:0001889 liver development;GO:0010629 negative regulation of gene expression;GO:0043410 positive regulation of MAPK cascade;GO:0030336 negative regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MJR6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N449-1", "uniprot_id": "A0A3Q1N449_BOVIN", "mass": 56562.0, "length": 499, "protein_name": "Transforming growth factor beta-1 proprotein", "gene_name": "TGFB1", "organism": "Bovine", "refseq_name": "transforming growth factor beta-1 proprotein isoform X2", "refseq_ac": "XP_024833718", "gene_names_uniprotkb": "TGFB1", "gene_names_refseq": "TGFB1", "protein_names_uniprotkb": "Transforming growth factor beta-1 proprotein", "protein_names_refseq": "transforming growth factor beta-1 proprotein isoform X2", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-114608); (R-BTA-2129379); (R-BTA-2173788); (R-BTA-2173789); (R-BTA-2173791); (R-BTA-3000170); (R-BTA-8941855); (R-BTA-8941858); (R-BTA-8951936); (R-BTA-9839389)", "pathway_count": 10, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required to maintain the Transforming growth factor beta-1 (TGF-beta-1) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-1 and regulates its activation via interaction with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS, that control activation of TGF-beta-1. Interaction with LRRC33/NRROS regulates activation of TGF-beta-1 in macrophages and microglia. Interaction with LRRC32/GARP controls activation of TGF-beta-1 on the surface of activated regulatory T-cells (Tregs). Interaction with integrins (ITGAV:ITGB6 or ITGAV:ITGB8) results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005160 transforming growth factor beta receptor binding;GO:0008083 growth factor activity;GO:0034714 type III transforming growth factor beta receptor binding;GO:0019899 enzyme binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0009986 cell surface;GO:0031012 extracellular matrix", "go_biological_process": "GO:0042307 positive regulation of protein import into nucleus;GO:0032700 negative regulation of interleukin-17 production;GO:0085029 extracellular matrix assembly;GO:0032740 positive regulation of interleukin-17 production;GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N449-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MQV3-1", "uniprot_id": "A0A3Q1MQV3_BOVIN", "mass": 129878.0, "length": 1175, "protein_name": "Thrombospondin-1", "gene_name": "THBS1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "THBS1", "gene_names_refseq": "", "protein_names_uniprotkb": "Thrombospondin-1; Glycoprotein G", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-114608); (R-BTA-186797); (R-BTA-216083); (R-BTA-5173214)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0002020 protease binding;GO:0005178 integrin binding;GO:0008201 heparin binding;GO:0042803 protein homodimerization activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0009897 external side of plasma membrane;GO:0005577 fibrinogen complex;GO:0016529 sarcoplasmic reticulum;GO:0031091 platelet alpha granule", "go_biological_process": "GO:0043032 positive regulation of macrophage activation;GO:0032693 negative regulation of interleukin-10 production;GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis;GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MQV3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MRR6-1", "uniprot_id": "A0A3Q1MRR6_BOVIN", "mass": 78464.0, "length": 687, "protein_name": "Protein kinase C delta type", "gene_name": "PRKCD", "organism": "Bovine", "refseq_name": "protein kinase C delta type isoform X1", "refseq_ac": "XP_024838244", "gene_names_uniprotkb": "PRKCD", "gene_names_refseq": "PRKCD", "protein_names_uniprotkb": "Protein kinase C delta type; 2.7.11.13; nPKC-delta", "protein_names_refseq": "protein kinase C delta type isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0030296 protein tyrosine kinase activator activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005911 cell-cell junction", "go_biological_process": "GO:0042307 positive regulation of protein import into nucleus;GO:0046627 negative regulation of insulin receptor signaling pathway;GO:1904385 cellular response to angiotensin;GO:2000753 positive regulation of glucosylceramide catabolic process;GO:2000755 positive regulation of sphingomyelin catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MRR6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MSS6-1", "uniprot_id": "A0A3Q1MSS6_BOVIN", "mass": 97874.0, "length": 882, "protein_name": "Cadherin-1", "gene_name": "CDH1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CDH1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cadherin-1; Epithelial cadherin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1474228); (R-BTA-216083); (R-BTA-351906); (R-BTA-418990); (R-BTA-5626467); (R-BTA-9764561); (R-BTA-9766229); (R-BTA-9768727); (R-BTA-9958810); (R-BTA-9958825)", "pathway_count": 10, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Promotes organization of radial actin fiber structure and cellular response to contractile forces, via its interaction with AMOTL2 which facilitates anchoring of radial actin fibers to CDH1 junction complexes at the cell membrane. Plays a role in the early stages of desmosome cell-cell junction formation via facilitating the recruitment of DSG2 and DSP to desmosome plaques. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7., [UniProtKB, UniProtKB, UniProtKB]; E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding;GO:0045295 gamma-catenin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005912 adherens junction;GO:0030027 lamellipodium;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0042307 positive regulation of protein import into nucleus;GO:0016477 cell migration;GO:0072659 protein localization to plasma membrane;GO:0030336 negative regulation of cell migration;GO:0000902 cell morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MSS6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MTW2-1", "uniprot_id": "A0A3Q1MTW2_BOVIN", "mass": 42797.0, "length": 421, "protein_name": "POU domain protein", "gene_name": "POU4F1", "organism": "Bovine", "refseq_name": "POU domain, class 4, transcription factor 1", "refseq_ac": "XP_024855911", "gene_names_uniprotkb": "POU4F1", "gene_names_refseq": "POU4F1", "protein_names_uniprotkb": "POU domain protein", "protein_names_refseq": "POU domain, class 4, transcription factor 1", "tax_id": 9913, "disease": "", "pathway": " (bta:784887); (R-BTA-6804759)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0051020 GTPase binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005737 cytoplasm;GO:0043005 neuron projection;GO:0000785 chromatin;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0048880 sensory system development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MTW2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MXL6-1", "uniprot_id": "A0A3Q1MXL6_BOVIN", "mass": 112914.0, "length": 990, "protein_name": "Kinesin-like protein", "gene_name": "KIF5B", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "KIF5B", "gene_names_refseq": "", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:514261); (R-BTA-2132295); (R-BTA-5625970); (R-BTA-983189)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0042802 identical protein binding;GO:0044877 protein-containing complex binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005874 microtubule;GO:0035253 ciliary rootlet;GO:0045335 phagocytic vesicle;GO:1904115 axon cytoplasm", "go_biological_process": "GO:0042391 regulation of membrane potential;GO:0032230 positive regulation of synaptic transmission, GABAergic;GO:0043268 positive regulation of potassium ion transport;GO:1903078 positive regulation of protein localization to plasma membrane;GO:0032418 lysosome localization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MXL6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N8K2-1", "uniprot_id": "A0A3Q1N8K2_BOVIN", "mass": 40468.0, "length": 356, "protein_name": "Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase", "gene_name": "ST8SIA1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ST8SIA1", "gene_names_refseq": "", "protein_names_uniprotkb": "Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; 2.4.3.8; Alpha-2,8-sialyltransferase 8A; Ganglioside GD3 synthase; Ganglioside GT3 synthase; Sialyltransferase 8A; Sialyltransferase St8Sia I", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-4085001)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.3.8", "go_molecular_function": "GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity;GO:0008373 sialyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0006665 sphingolipid metabolic process;GO:0009311 oligosaccharide metabolic process;GO:0006491 N-glycan processing;GO:0009101 glycoprotein biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N8K2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N9G5-1", "uniprot_id": "A0A3Q1N9G5_BOVIN", "mass": 46504.0, "length": 416, "protein_name": "Choline/ethanolaminephosphotransferase 1", "gene_name": "CEPT1", "organism": "Bovine", "refseq_name": "choline/ethanolaminephosphotransferase 1 isoform X1", "refseq_ac": "XP_005204147", "gene_names_uniprotkb": "CEPT1", "gene_names_refseq": "CEPT1", "protein_names_uniprotkb": "Choline/ethanolaminephosphotransferase 1; 1-alkenyl-2-acylglycerol choline phosphotransferase; 2.7.8.1; 2.7.8.22; 2.7.8.2", "protein_names_refseq": "choline/ethanolaminephosphotransferase 1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1483191); (R-BTA-1483213)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.8.2;2.7.8.1;2.7.8.22", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004142 diacylglycerol cholinephosphotransferase activity;GO:0004307 ethanolaminephosphotransferase activity;GO:0047359 1-alkenyl-2-acylglycerol choline phosphotransferase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0031965 nuclear membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006646 phosphatidylethanolamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N9G5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NAV6-1", "uniprot_id": "A0A3Q1NAV6_BOVIN", "mass": 23768.0, "length": 213, "protein_name": "Fibroblast growth factor", "gene_name": "FGF10", "organism": "Bovine", "refseq_name": "fibroblast growth factor 10 precursor", "refseq_ac": "NP_001193255", "gene_names_uniprotkb": "FGF10", "gene_names_refseq": "FGF10", "protein_names_uniprotkb": "Fibroblast growth factor; FGF", "protein_names_refseq": "fibroblast growth factor 10 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:326285); (R-BTA-109704); (R-BTA-1257604); (R-BTA-190370); (R-BTA-190377); (R-BTA-5654219); (R-BTA-5654221); (R-BTA-5654687); (R-BTA-5654688); (R-BTA-5654689); (R-BTA-5654693); (R-BTA-5654695); (R-BTA-5654699); (R-BTA-5654700); (R-BTA-5654726); (R-BTA-5654727); (R-BTA-5658623); (R-BTA-5673001); (R-BTA-6811558)", "pathway_count": 19, "publication_count": 8, "publication_id_list": "17582010;18163381;22457435;22959639;23641036;24650928;26194863;28000057", "class_list": "", "function": "BMP15 and FGF10 stimulate expansion of in cumulus-oocyte complexes by driving glucose metabolism toward hyaluronic acid production and controlling gene expression in the ovulatory cascade. Publication Status: Online-Only, [RefSeq, PubMed]; FGF10 and its receptor FGFR2b are more expressed in subordinate follicles; FGF10 acts as an important regulator of follicular growth in cattle., [RefSeq, PubMed]; FGF10 mRNA expression did not change during functional luteolysis, whereas FGFR2B mRNA abundance decreased significantly at 2, 4, and 12 hr after PGF2alpha, and returned to pretreatment levels for the period 24-64 hr post-PGF2alpha, [RefSeq, PubMed]; Genetic variability is an important component of the number of antral follicles in the bovine ovary., [RefSeq, PubMed]; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation., [UniProtKB, UniProtKB]; The present data suggest a role for FGF10 in the control of fetal folliculogenesis in cattle., [RefSeq, PubMed]; These data support a role for FGF10 and fibroblast growth factor receptor 2B in signaling to granulosa cells from theca cells and/or the oocyte., [RefSeq, PubMed]; We conclude that FGF10 and FGFR2B expression is increased in the future subordinate follicle before morphological deviation, which may contribute to follicle selection, [RefSeq, PubMed]; We found no difference between treatments regarding embryo production, developmental speed, and gene expression. CONCLUSION: In conclusion, the presence of FGF10 during IVM had no effect on embryo production, developmental speed, and gene expression., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0042056 chemoattractant activity;GO:0008083 growth factor activity;GO:0005111 type 2 fibroblast growth factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction;GO:0008284 positive regulation of cell population proliferation;GO:0043410 positive regulation of MAPK cascade;GO:0030036 actin cytoskeleton organization;GO:0051549 positive regulation of keratinocyte migration", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0A3Q1NAV6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NDF8-1", "uniprot_id": "A0A3Q1NDF8_BOVIN", "mass": 142936.0, "length": 1291, "protein_name": "NPC intracellular cholesterol transporter 1", "gene_name": "NPC1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NPC1", "gene_names_refseq": "", "protein_names_uniprotkb": "NPC intracellular cholesterol transporter 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0120020 cholesterol transfer activity;GO:0005319 lipid transporter activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane", "go_biological_process": "GO:0031579 membrane raft organization;GO:0008203 cholesterol metabolic process;GO:0009101 glycoprotein biosynthetic process;GO:0033344 cholesterol efflux;GO:0042632 cholesterol homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NDF8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NLZ6-1", "uniprot_id": "A0A3Q1NLZ6_BOVIN", "mass": 61906.0, "length": 570, "protein_name": "Natural resistance-associated macrophage protein 1", "gene_name": "SLC11A1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC11A1", "gene_names_refseq": "", "protein_names_uniprotkb": "Natural resistance-associated macrophage protein 1; Solute carrier family 11 member 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1222556); (R-BTA-425410); (R-BTA-6798695); (R-BTA-6803544)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Macrophage-specific antiporter that fluxes metal ions in either direction against a proton gradient. Localized to late endosomal lysosomal membranes, delivers bivalent cations from the cytosol into these acidic compartments where they may directly affect antimicrobial activity. Involved in iron metabolism and host natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0005384 manganese ion transmembrane transporter activity;GO:0051139 metal cation:proton antiporter activity;GO:0005381 iron ion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0070821 tertiary granule membrane;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0030670 phagocytic vesicle membrane", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0009617 response to bacterium;GO:0070574 cadmium ion transmembrane transport;GO:0098849 cellular detoxification of cadmium ion;GO:0034755 iron ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NLZ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPK8-1", "uniprot_id": "A0A3S5ZPK8_BOVIN", "mass": 101607.0, "length": 885, "protein_name": "Toll-like receptor 3", "gene_name": "TLR3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TLR3", "gene_names_refseq": "", "protein_names_uniprotkb": "Toll-like receptor 3", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1679131)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0042802 identical protein binding;GO:0003725 double-stranded RNA binding;GO:0044389 ubiquitin-like protein ligase binding;GO:0038187 pattern recognition receptor activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane", "go_biological_process": "GO:0032727 positive regulation of interferon-alpha production;GO:0045087 innate immune response;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0046330 positive regulation of JNK cascade;GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZPK8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MXX0-1", "uniprot_id": "F1MXX0_BOVIN", "mass": 83044.0, "length": 749, "protein_name": "MICOS complex subunit MIC60", "gene_name": "IMMT", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IMMT", "gene_names_refseq": "", "protein_names_uniprotkb": "MICOS complex subunit MIC60; Mitofilin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0061617 MICOS complex;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0042407 cristae formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MXX0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MVD0-1", "uniprot_id": "F1MVD0_BOVIN", "mass": 153213.0, "length": 1411, "protein_name": "Nuclear receptor coactivator", "gene_name": "NCOA3", "organism": "Bovine", "refseq_name": "nuclear receptor coactivator 3 isoform X1", "refseq_ac": "XP_002692539", "gene_names_uniprotkb": "NCOA3", "gene_names_refseq": "NCOA3", "protein_names_uniprotkb": "Nuclear receptor coactivator", "protein_names_refseq": "nuclear receptor coactivator 3 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:523707); (R-BTA-5687128); (R-BTA-9018519); (R-BTA-9841922)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.48;2.3.1.-;2.3.1.259", "go_molecular_function": "GO:0061733 protein-lysine-acetyltransferase activity;GO:0003713 transcription coactivator activity;GO:0046983 protein dimerization activity;GO:0016922 nuclear receptor binding;GO:0097718 disordered domain specific binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0070561 vitamin D receptor signaling pathway;GO:0032870 cellular response to hormone stimulus;GO:0048384 retinoic acid receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MVD0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O62664-1", "uniprot_id": "PGH1_BOVIN", "mass": 68805.0, "length": 600, "protein_name": "Prostaglandin G/H synthase 1", "gene_name": "PTGS1", "organism": "Bovine", "refseq_name": "prostaglandin G/H synthase 1 precursor", "refseq_ac": "NP_001098793", "gene_names_uniprotkb": "PTGS1; COX-1; COX1", "gene_names_refseq": "PTGS1", "protein_names_uniprotkb": "Prostaglandin G/H synthase 1; 1.14.99.1; COX-1; Cyclooxygenase-1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin H2 synthase 1; Prostaglandin-endoperoxide synthase 1", "protein_names_refseq": "COX-1; PGH synthase 1; PGHS-1; PHS 1; cyclooxygenase-1; prostaglandin G/H synthase 1 precursor; prostaglandin G/H synthase 1; prostaglandin G/H synthase and cyclooxygenase; prostaglandin H2 synthase 1", "tax_id": 9913, "disease": "", "pathway": " (bta:282022); (R-BTA-140180); (R-BTA-2162123)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "12080013;9348208", "class_list": "", "function": "Dual cyclooxygenase and peroxidase that plays an important role in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate ((5Z,8Z,11Z,14Z)-eicosatetraenoate, AA, C20:4(n-6)), with a particular role in the inflammatory response. The cyclooxygenase activity oxygenates AA to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and the peroxidase activity reduces PGG2 to the hydroxy endoperoxide prostaglandin H2 (PGH2), the precursor of all 2-series prostaglandins and thromboxanes. This complex transformation is initiated by abstraction of hydrogen at carbon 13 (with S-stereochemistry), followed by insertion of molecular O2 to form the endoperoxide bridge between carbon 9 and 11 that defines prostaglandins. The insertion of a second molecule of O2 (bis-oxygenase activity) yields a hydroperoxy group in PGG2 that is then reduced to PGH2 by two electrons. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells. Can also use linoleate (LA, (9Z,12Z)-octadecadienoate, C18:2(n-6)) as substrate and produce hydroxyoctadecadienoates (HODEs) in a regio- and stereospecific manner, being (9R)-HODE ((9R)-hydroxy-(10E,12Z)-octadecadienoate) and (13S)-HODE ((13S)-hydroxy-(9Z,11E)-octadecadienoate) its major products., [UniProtKB, UniProtKB]; There was no expression of COX-1, either mRNA or protein, on any day of the estrous cycle, [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "A7YWD4", "ec_number_list": "1.14.99.1", "go_molecular_function": "GO:0004666 prostaglandin-endoperoxide synthase activity;GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0004601 peroxidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005789 endoplasmic reticulum membrane;GO:0043005 neuron projection;GO:0005788 endoplasmic reticulum lumen;GO:0001750 photoreceptor outer segment", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0019371 cyclooxygenase pathway;GO:0001516 prostaglandin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "O62664-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MN01-1", "uniprot_id": "F1MN01_BOVIN", "mass": 167785.0, "length": 1481, "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CFTR", "gene_names_refseq": "", "protein_names_uniprotkb": "Cystic fibrosis transmembrane conductance regulator; 5.6.1.6; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-382556); (R-BTA-5627083); (R-BTA-8856825); (R-BTA-8856828); (R-BTA-9013406); (R-BTA-9646399)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Possesses an intrinsic ATPase activity and utilizes ATP to gate its channel; the passive flow of anions through the channel is gated by cycles of ATP binding and hydrolysis by the ATP-binding domains. The ion channel is also permeable to HCO(3)(-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.5.5;2.7.10.1;3.6.4.6;7.6.2.2;7.6.2.3;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;2.7.1.153;2.7.1.137;2.7.1.154;4.2.99.18;5.6.1.6;3.6.5.2;3.6.1.15;7.6.2.1;3.1.3.36;3.1.3.1;3.9.1.1;1.8.-.-;2.3.2.23;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.4.25.1;3.1.4.-;3.4.21.53;3.1.2.-;3.5.1.-;3.5.1.124;1.8.5.1", "go_molecular_function": "GO:0005260 intracellularly ATP-gated chloride channel activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity;GO:0019869 chloride channel inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005789 endoplasmic reticulum membrane;GO:0016324 apical plasma membrane;GO:0031901 early endosome membrane;GO:0055038 recycling endosome membrane", "go_biological_process": "GO:0015701 bicarbonate transport;GO:0071320 cellular response to cAMP;GO:1904322 cellular response to forskolin;GO:0048240 sperm capacitation;GO:0060081 membrane hyperpolarization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MN01-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5PJN2-1", "uniprot_id": "ERO1A_BOVIN", "mass": 54297.0, "length": 468, "protein_name": "ERO1-like protein alpha", "gene_name": "ERO1A", "organism": "Bovine", "refseq_name": "ERO1-like protein alpha precursor", "refseq_ac": "NP_001096818", "gene_names_uniprotkb": "ERO1A; ERO1L", "gene_names_refseq": "ERO1-L; ERO1A; ERO1L", "protein_names_uniprotkb": "ERO1-like protein alpha; 1.8.3.2; ERO1-L-alpha; ERO1-L; Endoplasmic reticulum oxidoreductase alpha; Endoplasmic reticulum oxidoreductin-1-like protein; Oxidoreductin-1-L-alpha", "protein_names_refseq": "ERO1-L-alpha; ERO1-like protein alpha precursor; ERO1-like protein alpha; Endoplasmic oxidoreductin-1-like protein; Oxidoreductin-1-L-alpha; endoplasmic reticulum oxidoreductase alpha; endoplasmic reticulum oxidoreductin-1-like protein", "tax_id": 9913, "disease": "", "pathway": " (bta:100125317); (R-BTA-3299685)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.3.2;5.3.4.1", "go_molecular_function": "GO:0071949 FAD binding;GO:0015035 protein-disulfide reductase activity;GO:0016971 flavin-dependent sulfhydryl oxidase activity;GO:0016972 thiol oxidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0005796 Golgi lumen;GO:0030425 dendrite;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0051209 release of sequestered calcium ion into cytosol;GO:0006457 protein folding;GO:0045454 cell redox homeostasis;GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0034976 response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A5PJN2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BGN7-1", "uniprot_id": "CGAS_BOVIN", "mass": 55953.0, "length": 498, "protein_name": "Cyclic GMP-AMP synthase", "gene_name": "CGAS", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CGAS; MB21D1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cyclic GMP-AMP synthase; 2'3'-cGAMP synthase; 2.7.7.86; cGAMP synthase; cGAS", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (2',3'-cGAMP) from ATP and GTP and plays a key role in innate immunity. Catalysis involves both the formation of a 2',5' phosphodiester linkage at the GpA step and the formation of a 3',5' phosphodiester linkage at the ApG step, producing c[G(2',5')pA(3',5')p]. Acts as a key DNA sensor: directly binds double-stranded DNA (dsDNA), inducing the formation of liquid-like droplets in which CGAS is activated, leading to synthesis of 2',3'-cGAMP, a second messenger that binds to and activates STING1, thereby triggering type-I interferon production. Preferentially binds long dsDNA (around 45 bp) and forms ladder-like networks that function cooperatively to stabilize individual cGAS-dsDNA complexes. Acts as a key foreign DNA sensor, the presence of double-stranded DNA (dsDNA) in the cytoplasm being a danger signal that triggers the immune responses. Has antiviral activity by sensing the presence of dsDNA from DNA viruses in the cytoplasm. Also acts as an innate immune sensor of infection by retroviruses by detecting the presence of reverse-transcribed DNA in the cytosol (By similarity). Detection of retroviral reverse-transcribed DNA in the cytosol may be indirect and be mediated via interaction with PQBP1, which directly binds reverse-transcribed retroviral DNA. Also detects the presence of DNA from bacteria (By similarity). 2',3'-cGAMP can be transferred from producing cells to neighboring cells through gap junctions, leading to promote STING1 activation and convey immune response to connecting cells. 2',3'-cGAMP can also be transferred between cells by virtue of packaging within viral particles contributing to IFN-induction in newly infected cells in a cGAS-independent but STING1-dependent manner. Also senses the presence of neutrophil extracellular traps (NETs) that are translocated to the cytosol following phagocytosis, leading to synthesis of 2',3'-cGAMP (By similarity). In addition to foreign DNA, can also be activated by endogenous nuclear or mitochondrial DNA (By similarity). When self-DNA leaks into the cytosol during cellular stress (such as mitochondrial stress, DNA damage, mitotic arrest or senescence), or is present in form of cytosolic micronuclei, CGAS is activated leading to a state of sterile inflammation. Acts as a regulator of cellular senescence by binding to cytosolic chromatin fragments that are present in senescent cells, leading to trigger type-I interferon production via STING1 and promote cellular senescence. Also involved in the inflammatory response to genome instability and double-stranded DNA breaks: acts by localizing to micronuclei arising from genome instability. Micronuclei, which as frequently found in cancer cells, consist of chromatin surrounded by its own nuclear membrane: following breakdown of the micronuclear envelope, a process associated with chromothripsis, CGAS binds self-DNA exposed to the cytosol, leading to 2',3'-cGAMP synthesis and subsequent activation of STING1 and type-I interferon production (By similarity). In a healthy cell, CGAS is however kept inactive even in cellular events that directly expose it to self-DNA, such as mitosis, when cGAS associates with chromatin directly after nuclear envelope breakdown or remains in the form of postmitotic persistent nuclear cGAS pools bound to chromatin (By similarity). Nuclear CGAS is inactivated by chromatin via direct interaction with nucleosomes, which block CGAS from DNA binding and thus prevent CGAS-induced autoimmunity. Also acts as a suppressor of DNA repair in response to DNA damage: inhibits homologous recombination repair by interacting with PARP1, the CGAS-PARP1 interaction leading to impede the formation of the PARP1-TIMELESS complex (By similarity). In addition to DNA, also sense translation stress: in response to translation stress, translocates to the cytosol and associates with collided ribosomes, promoting its activation and triggering type-I interferon production (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.7.86", "go_molecular_function": "GO:0061501 2',3'-cyclic GMP-AMP synthase activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0005525 GTP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0035861 site of double-strand break;GO:0016604 nuclear body", "go_biological_process": "GO:0071360 cellular response to exogenous dsRNA;GO:2000042 negative regulation of double-strand break repair via homologous recombination;GO:0006281 DNA repair;GO:0045087 innate immune response;GO:0051607 defense response to virus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E1BGN7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6H7G2-1", "uniprot_id": "DBNL_BOVIN", "mass": 47723.0, "length": 423, "protein_name": "Drebrin-like protein", "gene_name": "DBNL", "organism": "Bovine", "refseq_name": "drebrin-like protein", "refseq_ac": "NP_001092440", "gene_names_uniprotkb": "DBNL", "gene_names_refseq": "DBNL", "protein_names_uniprotkb": "Drebrin-like protein", "protein_names_refseq": "drebrin-like protein", "tax_id": 9913, "disease": "", "pathway": " (bta:514706)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0003779 actin binding;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005769 early endosome;GO:0005829 cytosol;GO:0014069 postsynaptic density;GO:0030027 lamellipodium", "go_biological_process": "GO:0006897 endocytosis;GO:0048812 neuron projection morphogenesis;GO:0007416 synapse assembly;GO:0002250 adaptive immune response;GO:0098974 postsynaptic actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A6H7G2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MMS9-1", "uniprot_id": "ITA3_BOVIN", "mass": 116407.0, "length": 1050, "protein_name": "Integrin alpha-3", "gene_name": "ITGA3", "organism": "Bovine", "refseq_name": "integrin alpha-3 precursor", "refseq_ac": "NP_001289593", "gene_names_uniprotkb": "ITGA3", "gene_names_refseq": "GAPB3; ITGA3", "protein_names_uniprotkb": "Integrin alpha-3; CD49 antigen-like family member C; GAPB3; Galactoprotein B3; VLA-3 subunit alpha", "protein_names_refseq": "CD49 antigen-like family member C; Galactoprotein B3; Integrin alpha-3; VLA-3 subunit alpha; integrin alpha-3 precursor; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); use the SwissProt name for F1MMS9", "tax_id": 9913, "disease": "", "pathway": " (bta:508490); (R-BTA-216083); (R-BTA-8874081)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "21237282", "class_list": "", "function": "Formation of CD151-integrin complex was likely to be a prerequisite for CD151-induced angiogenesis and signaling pathways, [RefSeq, PubMed]; Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 13, "predicted_n_glycosites": 13, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0046982 protein heterodimerization activity;GO:0038023 signaling receptor activity;GO:0002020 protease binding", "go_cellular_component": "GO:0009986 cell surface;GO:0031527 filopodium membrane;GO:0008305 integrin complex;GO:0098978 glutamatergic synapse;GO:0048787 presynaptic active zone membrane", "go_biological_process": "GO:0048731 system development;GO:0007229 integrin-mediated signaling pathway;GO:0030154 cell differentiation;GO:0098609 cell-cell adhesion;GO:0050900 leukocyte migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MMS9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BJS7-1", "uniprot_id": "LIN41_BOVIN", "mass": 93192.0, "length": 868, "protein_name": "E3 ubiquitin-protein ligase TRIM71", "gene_name": "TRIM71", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TRIM71; LIN41", "gene_names_refseq": "", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM71; 2.3.2.27; Protein lin-41 homolog; RING-type E3 ubiquitin transferase TRIM71; Tripartite motif-containing protein 71", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:531886); (R-BTA-983168)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "19393038;21315162", "class_list": "", "function": "E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance (By similarity). Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A (By similarity). In addition, participates in post-transcriptional mRNA repression in a miRNA independent mechanism (By similarity). Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1 (By similarity). Specific regulator of miRNA biogenesis. Binds to miRNA MIR29A hairpin and postranscriptionally modulates MIR29A levels, which indirectly regulates TET proteins expression (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F2Y8T8", "ec_number_list": "2.3.2.27;2.3.2.23;2.3.2.31;2.3.2.26;2.3.2.-;2.3.2.34;2.3.2.25;2.3.2.24", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0035198 miRNA binding;GO:0004842 ubiquitin-protein transferase activity;GO:0030371 translation repressor activity", "go_cellular_component": "GO:0000932 P-body", "go_biological_process": "GO:0010608 post-transcriptional regulation of gene expression;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0021915 neural tube development;GO:0000082 G1/S transition of mitotic cell cycle;GO:0000209 protein polyubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "E1BJS7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BH29-1", "uniprot_id": "ALKB5_BOVIN", "mass": 44097.0, "length": 394, "protein_name": "RNA demethylase ALKBH5", "gene_name": "ALKBH5", "organism": "Bovine", "refseq_name": "RNA demethylase ALKBH5", "refseq_ac": "NP_001192446", "gene_names_uniprotkb": "ALKBH5", "gene_names_refseq": "ALKBH5", "protein_names_uniprotkb": "RNA demethylase ALKBH5; 1.14.11.53; Alkylated DNA repair protein alkB homolog 5; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5", "protein_names_refseq": "AlkB family member 5, RNA demethylase; RNA demethylase ALKBH5; alkB, alkylation repair homolog 5; alkylated DNA repair protein alkB homolog 5; alpha-ketoglutarate-dependent dioxygenase alkB homolog 5", "tax_id": 9913, "disease": "", "pathway": " (bta:533303); (R-BTA-73943)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Dioxygenase that specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Demethylates RNA by oxidative demethylation, which requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing, translation and export. Can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro) (By similarity). Required for the late meiotic and haploid phases of spermatogenesis by mediating m6A demethylation in spermatocytes and round spermatids: m6A demethylation of target transcripts is required for correct splicing and the production of longer 3'-UTR mRNAs in male germ cells (By similarity). Involved in paraspeckle assembly, a nuclear membraneless organelle, by undergoing liquid-liquid phase separation. Paraspeckle assembly is coupled with m6A demethylation of RNAs, such as NEAT1 non-coding RNA (By similarity). Also acts as a negative regulator of T-cell development: inhibits gamma-delta T-cell proliferation via demethylation of JAG1 and NOTCH2 transcripts. Inhibits regulatory T-cell (Treg) recruitment by mediating demethylation and destabilization of CCL28 mRNAs (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.11.53", "go_molecular_function": "GO:0046872 metal ion binding;GO:0016706 2-oxoglutarate-dependent dioxygenase activity;GO:0035515 oxidative RNA demethylase activity;GO:1990931 mRNA N6-methyladenosine dioxygenase activity;GO:0140693 molecular condensate scaffold activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0042382 paraspeckles", "go_biological_process": "GO:0006397 mRNA processing;GO:0006417 regulation of translation;GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0001666 response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E1BH29-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N3B8-1", "uniprot_id": "OAS2_BOVIN", "mass": 81967.0, "length": 714, "protein_name": "2'-5'-oligoadenylate synthase 2", "gene_name": "OAS2", "organism": "Bovine", "refseq_name": "2'-5'-oligoadenylate synthase 2", "refseq_ac": "NP_001019728", "gene_names_uniprotkb": "OAS2", "gene_names_refseq": "OAS2", "protein_names_uniprotkb": "2'-5'-oligoadenylate synthase 2; (2-5')oligo(A) synthase 2; 2-5A synthase 2; 2.7.7.84", "protein_names_refseq": "(2-5')oligo(A) synthase 2; 2'-5'-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; 2-5A synthase 2", "tax_id": 9913, "disease": "", "pathway": " (bta:529660)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "17024523;19393038", "class_list": "", "function": "Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. Activated by detection of double stranded RNA (dsRNA): catalyzes the formation of 2'-5'-oligoadenylates (2-5A) from polymerization of ATP which then bind to the inactive monomeric form of ribonuclease L (RNASEL) leading to its dimerization and subsequent activation. Activation of RNASEL leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNASEL-dependent pathway or an alternative antiviral pathway independent of RNASEL. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation (By similarity). May act as a negative regulator of lactation, stopping lactation in virally infected mammary gland lobules, thereby preventing transmission of viruses to neonates (By similarity). Non-infected lobules would not be affected, allowing efficient pup feeding during infection (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q53AV7", "ec_number_list": "2.7.7.84", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0003725 double-stranded RNA binding;GO:0001730 2'-5'-oligoadenylate synthetase activity;GO:0003723 RNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0070106 interleukin-27-mediated signaling pathway;GO:0051607 defense response to virus;GO:0045071 negative regulation of viral genome replication;GO:0060337 type I interferon-mediated signaling pathway;GO:0009615 response to virus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1N3B8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G3X745-1", "uniprot_id": "GPC1_BOVIN", "mass": 61007.0, "length": 559, "protein_name": "Glypican-1", "gene_name": "GPC1", "organism": "Bovine", "refseq_name": "glypican-1", "refseq_ac": "XP_010802238", "gene_names_uniprotkb": "GPC1", "gene_names_refseq": "GPC1", "protein_names_uniprotkb": "Glypican-1", "protein_names_refseq": "glypican-1", "tax_id": 9913, "disease": "", "pathway": " (bta:518114); (R-BTA-1971475); (R-BTA-2022928); (R-BTA-2024096); (R-BTA-376176); (R-BTA-975634); (R-BTA-9769735); (R-BTA-9769739)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN (C) to PRNP (Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling (By similarity)., [UniProtKB]; Cell surface proteoglycan., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 2, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "Q2KJ65", "ec_number_list": "", "go_molecular_function": "GO:0043236 laminin binding;GO:0005507 copper ion binding;GO:0017134 fibroblast growth factor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005768 endosome;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0031012 extracellular matrix", "go_biological_process": "GO:0016477 cell migration;GO:0030200 heparan sulfate proteoglycan catabolic process;GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway;GO:2001016 positive regulation of skeletal muscle cell differentiation;GO:1905475 regulation of protein localization to membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "G3X745-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O97831-1", "uniprot_id": "AGRL1_BOVIN", "mass": 162205.0, "length": 1472, "protein_name": "Adhesion G protein-coupled receptor L1", "gene_name": "ADGRL1", "organism": "Bovine", "refseq_name": "adhesion G protein-coupled receptor L1 precursor", "refseq_ac": "NP_001107200", "gene_names_uniprotkb": "ADGRL1; LPHN1", "gene_names_refseq": "ADGRL1; LPHN1", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor L1; CIRL-1; Calcium-independent alpha-latrotoxin receptor 1; Latrophilin-1", "protein_names_refseq": "CIRL-1; adhesion G protein-coupled receptor L1 precursor; calcium-independent alpha-latrotoxin receptor 1; latrophilin-1", "tax_id": 9913, "disease": "", "pathway": " (bta:788252)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10025961;9261169", "class_list": "", "function": "Calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "O97830", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0050839 cell adhesion molecule binding;GO:0016524 latrotoxin receptor activity;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0030424 axon;GO:0030426 growth cone;GO:0045202 synapse", "go_biological_process": "GO:0007165 signal transduction;GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "O97831-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q76LV2-1", "uniprot_id": "HS90A_BOVIN", "mass": 84731.0, "length": 733, "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "organism": "Bovine", "refseq_name": "heat shock protein HSP 90-alpha", "refseq_ac": "NP_001012688", "gene_names_uniprotkb": "HSP90AA1; HSP90A; HSPCA", "gene_names_refseq": "HSP90AA1; HSPCA", "protein_names_uniprotkb": "Heat shock protein HSP 90-alpha; 3.6.4.10", "protein_names_refseq": "heat shock 90 kDa protein 1; heat shock 90kD protein 1, alpha; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock protein HSP 90-alpha", "tax_id": 9913, "disease": "", "pathway": " (bta:281832); (R-BTA-1227986); (R-BTA-1474151); (R-BTA-168928); (R-BTA-2029482); (R-BTA-203615); (R-BTA-2565942); (R-BTA-3371497); (R-BTA-3371511); (R-BTA-3371568); (R-BTA-3371571); (R-BTA-380259); (R-BTA-380270); (R-BTA-380284); (R-BTA-380320); (R-BTA-399954); (R-BTA-4420097); (R-BTA-5218920); (R-BTA-5620912); (R-BTA-5675482); (R-BTA-6798695); (R-BTA-8854518); (R-BTA-8863795); (R-BTA-8939211); (R-BTA-9009391); (R-BTA-9013418); (R-BTA-9018519); (R-BTA-9652282)", "pathway_count": 28, "publication_count": 6, "publication_id_list": "21465483;29353403;32888122;38395401;38471304;39096401", "class_list": "", "function": "Association analysis of HSP90AA1 polymorphism with thermotolerance in tropically adapted Indian crossbred cattle. Publication Status: Online-Only, [RefSeq, PubMed]; Characterization of a putative ribosome binding site at the 5' untranslated region of bovine heat shock protein 90., [RefSeq, PubMed]; Inhibition of HSP90AA1 induces abnormalities in bovine oocyte maturation and embryonic development. Publication Status: Online-Only, [RefSeq, PubMed]; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interaction with various co-chaperone proteins or complexes, that act as adapters, simultaneously able to interact with the specific client and the central chaperone itself. Recruitment of ATP and co-chaperone followed by client protein forms a functional chaperone. After the completion of the chaperoning process, properly folded client protein and co-chaperone leave HSP90 in an ADP-bound partially open conformation and finally, ADP is released from HSP90 which acquires an open conformation for the next cycle. Plays a critical role in mitochondrial import, delivers preproteins to the mitochondrial import receptor TOMM70. Apart from its chaperone activity, it also plays a role in the regulation of the transcription machinery. HSP90 and its co-chaperones modulate transcription at least at three different levels. In the first place, they alter the steady-state levels of certain transcription factors in response to various physiological cues. Second, they modulate the activity of certain epigenetic modifiers, such as histone deacetylases or DNA methyl transferases, and thereby respond to the change in the environment. Third, they participate in the eviction of histones from the promoter region of certain genes and thereby turn on gene expression. Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Antagonizes STUB1-mediated inhibition of TGF-beta signaling via inhibition of STUB1-mediated SMAD3 ubiquitination and degradation. Mediates the association of TOMM70 with IRF3 or TBK1 in mitochondrial outer membrane which promotes host antiviral response., [UniProtKB, UniProtKB]; The HSP90AA1 gene is involved in heat stress responses and its functional genetic polymorphisms are associated with heat tolerance in Holstein cows., [RefSeq, PubMed]; There was an association between genetic variations in the Hsp90AA1 and thermoresistance., [RefSeq, PubMed]; This study showed that ubiquitinated ALK5 and phosphorylated heat shock protein 27 specifically accumulate in the cytoskeleton fraction, and ALK1 and ALK5 interact with heat shock protein 90(HSP90)., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.42;3.6.4.12;2.5.1.18;5.6.2.4;3.6.4.13;2.7.1.1;2.7.11.24;2.3.2.27;2.7.10.2;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;2.7.11.1;2.7.11.39;3.2.1.23;2.4.2.1;5.2.1.8;3.6.4.10;4.1.2.13;3.6.1.6;2.7.10.1;5.6.2.3;3.6.5.-;3.1.6.14;1.1.1.205;2.7.1.11;2.7.11.21;3.6.5.2;5.6.2.-;2.7.4.3;3.6.4.-;3.1.-.-;2.7.11.22;2.7.11.23;2.3.2.26;2.4.1.25;3.2.1.33;4.2.99.18;3.4.23.5;5.6.1.6;1.13.11.34;1.13.11.12;3.6.1.15;7.6.2.1;1.14.13.39;3.1.3.16;1.16.3.1;1.11.1.6;2.7.11.11;3.4.18.1;3.4.22.1;3.1.3.1;3.9.1.1;3.4.22.27;2.7.11.26;3.4.24.35;3.1.1.47;5.3.2.1;5.3.3.12;3.4.19.1;2.7.1.35;5.6.2.5;2.4.1.1;3.5.1.23;3.5.1.-;3.4.22.52;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;2.3.3.8;5.4.2.11;5.4.2.4;3.3.2.6;3.4.11.4;3.4.21.46;2.7.4.6;2.7.13.3;4.1.2.4;5.3.1.9;5.1.3.-;5.3.99.3;3.1.4.-;2.4.2.7;4.2.1.24;3.4.21.53;3.1.11.-", "go_molecular_function": "GO:0030911 TPR domain binding;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0009409 response to cold;GO:0045429 positive regulation of nitric oxide biosynthetic process;GO:0034605 cellular response to heat;GO:0050821 protein stabilization;GO:0002230 positive regulation of defense response to virus by host", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q76LV2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1A4K3-1", "uniprot_id": "DDB1_BOVIN", "mass": 126930.0, "length": 1140, "protein_name": "DNA damage-binding protein 1", "gene_name": "DDB1", "organism": "Bovine", "refseq_name": "DNA damage-binding protein 1", "refseq_ac": "NP_001073731", "gene_names_uniprotkb": "DDB1", "gene_names_refseq": "DDB1", "protein_names_uniprotkb": "DNA damage-binding protein 1; Damage-specific DNA-binding protein 1", "protein_names_refseq": "DNA damage-binding protein 1; damage-specific DNA binding protein 1, 127kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:511951); (R-BTA-110314); (R-BTA-5696394); (R-BTA-5696395); (R-BTA-5696400); (R-BTA-6781823); (R-BTA-6782135); (R-BTA-6782210); (R-BTA-8951664)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "22542975", "class_list": "", "function": "Bovine herpesvirus-1 VP8 interacts with DDB1 and is monoubiquitinated during infection., [RefSeq, PubMed]; Component of complexes involved in DNA repair and protein ubiquitination. May play a role in the regulation of the circadian clock., [UniProtKB, UniProtKB]; Protein, which is both involved in DNA repair and protein ubiquitination, as part of the UV-DDB complex and DCX (DDB1-CUL4-X-box) complexes, respectively. Core component of the UV-DDB complex (UV-damaged DNA-binding protein complex), a complex that recognizes UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches. Also functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the DCX E3 ubiquitin-protein ligase complex is determined by the variable substrate recognition component recruited by DDB1. DCX(DDB2) (also known as DDB1-CUL4-ROC1, CUL4-DDB-ROC1 and CUL4-DDB-RBX1) may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage. The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair. DCX(DDB2) also ubiquitinates XPC, which may enhance DNA-binding by XPC and promote NER. DCX(DTL) plays a role in PCNA-dependent polyubiquitination of CDT1 and MDM2-dependent ubiquitination of TP53 in response to radiation-induced DNA damage and during DNA replication. DCX(ERCC8) (the CSA complex) plays a role in transcription-coupled repair (TCR). The DDB1-CUL4A-DTL E3 ligase complex regulates the circadian clock function by mediating the ubiquitination and degradation of CRY1 (By similarity). DDB1-mediated CRY1 degradation promotes FOXO1 protein stability and FOXO1-mediated gluconeogenesis in the liver (By similarity). By acting on TET dioxygenses, essential for oocyte maintenance at the primordial follicle stage, hence essential for female fertility (By similarity). Maternal factor required for proper zygotic genome activation and genome reprogramming (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003684 damaged DNA binding;GO:0044877 protein-containing complex binding;GO:0097602 cullin family protein binding;GO:0071987 WD40-repeat domain binding", "go_cellular_component": "GO:0031464 Cul4A-RING E3 ubiquitin ligase complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0035861 site of double-strand break", "go_biological_process": "GO:0006281 DNA repair;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination;GO:0042752 regulation of circadian rhythm;GO:0048511 rhythmic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A1A4K3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BGL6-1", "uniprot_id": "E1BGL6_BOVIN", "mass": 100415.0, "length": 868, "protein_name": "Extracellular sulfatase", "gene_name": "SULF1", "organism": "Bovine", "refseq_name": "extracellular sulfatase Sulf-1 isoform X4", "refseq_ac": "XP_024857604", "gene_names_uniprotkb": "SULF1", "gene_names_refseq": "SULF1", "protein_names_uniprotkb": "Extracellular sulfatase; 3.1.6.-", "protein_names_refseq": "extracellular sulfatase Sulf-1 isoform X4", "tax_id": 9913, "disease": "", "pathway": " (bta:535166)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.6.14;3.1.6.1;3.1.6.-;3.1.6.15;3.1.6.18", "go_molecular_function": "GO:0008449 N-acetylglucosamine-6-sulfatase activity;GO:0046872 metal ion binding;GO:0004065 arylsulfatase activity;GO:0016787 hydrolase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0045121 membrane raft", "go_biological_process": "GO:0030201 heparan sulfate proteoglycan metabolic process;GO:0060384 innervation;GO:0014846 esophagus smooth muscle contraction;GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway;GO:0010575 positive regulation of vascular endothelial growth factor production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BGL6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1A4R9-1", "uniprot_id": "AP2A_BOVIN", "mass": 47984.0, "length": 437, "protein_name": "Transcription factor AP-2-alpha", "gene_name": "TFAP2A", "organism": "Bovine", "refseq_name": "transcription factor AP-2-alpha", "refseq_ac": "NP_001073697", "gene_names_uniprotkb": "TFAP2A", "gene_names_refseq": "TFAP2A", "protein_names_uniprotkb": "Transcription factor AP-2-alpha; AP-2 transcription factor; AP-2; AP2-alpha; Activating enhancer-binding protein 2-alpha; Activator protein 2", "protein_names_refseq": "AP-2 transcription factor; AP2-alpha; activating enhancer-binding protein 2-alpha; activator protein 2; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); transcription factor AP-2-alpha", "tax_id": 9913, "disease": "", "pathway": " (bta:505849); (R-BTA-8864260); (R-BTA-8866904); (R-BTA-8866907); (R-BTA-8869496); (R-BTA-9834899)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "22425968", "class_list": "", "function": "Electroporating siRNA into bovine trophoblast cells could be an efficient method to manipulate binucleate trophoblast giant cells function and to study the regulation mechanism of specific gene transcription., [RefSeq, PubMed]; Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18 and C/EBP alpha. Is involved in the negative regulation of Wnt canonical signaling, and is a transcriptional repressor of MYC (By similarity). AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0042127 regulation of cell population proliferation;GO:0042472 inner ear morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A1A4R9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5D979-1", "uniprot_id": "SPRTN_BOVIN", "mass": 54521.0, "length": 487, "protein_name": "DNA-dependent metalloprotease SPRTN", "gene_name": "SPRTN", "organism": "Bovine", "refseq_name": "DNA-dependent metalloprotease SPRTN", "refseq_ac": "NP_001091551", "gene_names_uniprotkb": "SPRTN", "gene_names_refseq": "C1orf124; C28H1orf124; SPRTN", "protein_names_uniprotkb": "DNA-dependent metalloprotease SPRTN; 3.4.24.-; Protein with SprT-like domain at the N terminus; Spartan", "protein_names_refseq": "DNA-dependent metalloprotease SPRTN; protein with SprT-like domain at the N terminus; spartan; sprT-like domain-containing protein Spartan; zinc finger RAD18 domain-containing protein C1orf124 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:534918); (R-BTA-110320)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "DNA-dependent metalloendopeptidase that mediates the proteolytic cleavage of covalent DNA-protein cross-links (DPCs) during DNA synthesis, thereby playing a key role in maintaining genomic integrity. DPCs are highly toxic DNA lesions that interfere with essential chromatin transactions, such as replication and transcription, and which are induced by reactive agents, such as UV light or formaldehyde. Associates with the DNA replication machinery and specifically removes DPCs during DNA synthesis. Catalyzes proteolytic cleavage of the HMCES DNA-protein cross-link following unfolding by the BRIP1/FANCJ helicase. Acts as a pleiotropic protease for DNA-binding proteins cross-linked with DNA, such as TOP1, TOP2A, histones H3 and H4. Mediates degradation of DPCs that are not ubiquitinated, while it is not able to degrade ubiquitinated DPCs. SPRTN activation requires polymerase collision with DPCs followed by helicase bypass of DPCs. Involved in recruitment of VCP/p97 to sites of DNA damage. Also acts as an activator of CHEK1 during normal DNA replication by mediating proteolytic cleavage of CHEK1, thereby promoting CHEK1 removal from chromatin and subsequent activation. Does not activate CHEK1 in response to DNA damage. May also act as a 'reader' of ubiquitinated PCNA: recruited to sites of UV damage and interacts with ubiquitinated PCNA and RAD18, the E3 ubiquitin ligase that monoubiquitinates PCNA. Facilitates chromatin association of RAD18 and is required for efficient PCNA monoubiquitination, promoting a feed-forward loop to enhance PCNA ubiquitination and translesion DNA synthesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.24.-;2.7.7.7;3.6.4.6", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding;GO:0031593 polyubiquitin modification-dependent protein binding;GO:0003690 double-stranded DNA binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0000785 chromatin", "go_biological_process": "GO:0006508 proteolysis;GO:0006974 DNA damage response;GO:0009411 response to UV;GO:0031398 positive regulation of protein ubiquitination;GO:0016540 protein autoprocessing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A5D979-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BE10-1", "uniprot_id": "PLD6_BOVIN", "mass": 25150.0, "length": 220, "protein_name": "Mitochondrial cardiolipin hydrolase", "gene_name": "PLD6", "organism": "Bovine", "refseq_name": "mitochondrial cardiolipin hydrolase", "refseq_ac": "NP_001258919", "gene_names_uniprotkb": "PLD6", "gene_names_refseq": "PLD6; mitoPLD", "protein_names_uniprotkb": "Mitochondrial cardiolipin hydrolase; 3.1.4.-; Choline phosphatase 6; MitoPLD; Mitochondrial phospholipase; PLD 6; Phosphatidylcholine-hydrolyzing phospholipase D6; Phospholipase D6", "protein_names_refseq": "choline phosphatase 6; mitochondrial cardiolipin hydrolase; mitochondrial phospholipase; phosphatidylcholine-hydrolyzing phospholipase D6", "tax_id": 9913, "disease": "", "pathway": " (bta:526651); (R-BTA-1483166)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Presents phospholipase and nuclease activities, depending on the different physiological conditions. Interaction with Mitoguardin (MIGA1 or MIGA2) affects the dimer conformation, facilitating the lipase activity over the nuclease activity. Plays a key role in mitochondrial fusion and fission via its phospholipase activity. In its phospholipase role, it uses the mitochondrial lipid cardiolipin as substrate to generate phosphatidate (PA or 1,2-diacyl-sn-glycero-3-phosphate), a second messenger signaling lipid. Production of PA facilitates Mitofusin-mediated fusion, whereas the cleavage of PA by the Lipin family of phosphatases produces diacylgycerol (DAG) which promotes mitochondrial fission. Both Lipin and DAG regulate mitochondrial dynamics and membrane fusion/fission, important processes for adapting mitochondrial metabolism to changes in cell physiology. Mitochondrial fusion enables cells to cope with the increased nucleotide demand during DNA synthesis (By similarity). Mitochondrial function and dynamics are closely associated with biological processes such as cell growth, proliferation, and differentiation. Mediator of MYC activity, promotes mitochondrial fusion and activates AMPK which in turn inhibits YAP/TAZ, thereby inducing cell growth and proliferation. The endonuclease activity plays a critical role in PIWI-interacting RNA (piRNA) biogenesis during spermatogenesis. Implicated in spermatogenesis and sperm fertility in testicular germ cells, its single strand-specific nuclease activity is critical for the biogenesis/maturation of PIWI-interacting RNA (piRNA). MOV10L1 selectively binds to piRNA precursors and funnels them to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins. Cleaves either DNA or RNA substrates with similar affinity, producing a 5' phosphate end, in this way it participates in the processing of primary piRNA transcripts. piRNAs provide essential protection against the activity of mobile genetic elements. piRNA-mediated transposon silencing is thus critical for maintaining genome stability, in particular in germline cells when transposons are mobilized as a consequence of wide-spread genomic demethylation. PA may act as signaling molecule in the recognition/transport of the precursor RNAs of primary piRNAs. Interacts with tesmin in testes, suggesting a role in spermatogenesis via association with its interacting partner (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.4.-", "go_molecular_function": "GO:0035755 cardiolipin hydrolase activity;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0016891 RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0031965 nuclear membrane", "go_biological_process": "GO:0030719 P granule organization;GO:0016042 lipid catabolic process;GO:0007286 spermatid development;GO:0008053 mitochondrial fusion;GO:0034587 piRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BE10-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MHA1-1", "uniprot_id": "F1MHA1_BOVIN", "mass": 434786.0, "length": 4001, "protein_name": "Histone-lysine N-methyltransferase", "gene_name": "KMT2A", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "KMT2A", "gene_names_refseq": "", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase; 2.1.1.364", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3214841); (R-BTA-8936459); (R-BTA-8939236); (R-BTA-9772755); (R-BTA-9909649)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 7, "predicted_n_glycosites": 0, "predicted_o_glycosites": 7, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.85;2.3.1.48;2.1.1.37;2.1.1.364;2.1.1.319;2.1.1.359;2.1.1.355;2.1.1.354;2.1.1.362;2.1.1.361", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0140945 histone H3K4 monomethyltransferase activity;GO:0003682 chromatin binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0035097 histone methyltransferase complex;GO:0071339 MLL1 complex", "go_biological_process": "GO:0035162 embryonic hemopoiesis;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048511 rhythmic process;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MHA1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MWQ3-1", "uniprot_id": "F1MWQ3_BOVIN", "mass": 50775.0, "length": 462, "protein_name": "Retinoic acid receptor alpha", "gene_name": "RARA", "organism": "Bovine", "refseq_name": "retinoic acid receptor alpha", "refseq_ac": "NP_001014942", "gene_names_uniprotkb": "RARA", "gene_names_refseq": "RARA", "protein_names_uniprotkb": "Retinoic acid receptor alpha", "protein_names_refseq": "RAR-alpha; retinoic acid receptor alpha", "tax_id": 9913, "disease": "", "pathway": " (bta:534280); (R-BTA-383280); (R-BTA-4090294); (R-BTA-5362517); (R-BTA-9616222)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "18641053", "class_list": "", "function": "Increased expression of mammary TRbeta1 and DIO2, and decreased RXRalpha, provide a mechanism to increase thyroid hormone activity within the mammary gland during lactation., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0008270 zinc ion binding;GO:0019904 protein domain specific binding;GO:0051393 alpha-actinin binding;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0000785 chromatin", "go_biological_process": "GO:0032736 positive regulation of interleukin-13 production;GO:0032754 positive regulation of interleukin-5 production;GO:0060010 Sertoli cell fate commitment;GO:0008284 positive regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MWQ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6QPB3-1", "uniprot_id": "COHA1_BOVIN", "mass": 149154.0, "length": 1473, "protein_name": "Collagen alpha-1(XVII) chain", "gene_name": "COL17A1", "organism": "Bovine", "refseq_name": "collagen alpha-1(XVII) chain", "refseq_ac": "NP_001095450", "gene_names_uniprotkb": "COL17A1; BP180; BPAG2", "gene_names_refseq": "BP180; BPAG2; COL17A1", "protein_names_uniprotkb": "Collagen alpha-1(XVII) chain; 180 kDa bullous pemphigoid antigen 2; Bullous pemphigoid antigen 2", "protein_names_refseq": "180 kDa bullous pemphigoid antigen 2; bullous pemphigoid antigen 180; bullous pemphigoid antigen 2; collagen alpha-1(XVII) chain; collagen, type XVII, alpha 1; type XVII collagen alpha-1", "tax_id": 9913, "disease": "", "pathway": " (bta:513804)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12761182;9545306", "class_list": "", "function": "May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane., [UniProtKB]; Results show that the cleavage of BP180 occurring within the NC16A domain is mediated by a membrane-associated metalloprotease and suggest involvement of the cleavage in hemidesmosomal disassembly(bullous pemphigoid antigen 180/type XVII collagen), [RefSeq, PubMed]; The 120 kDa linear IgA disease antigen homolog is an anchoring filament component involved in dermal-epidermal cohesion., [UniProtKB, UniProtKB, UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 1, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030020 extracellular matrix structural constituent conferring tensile strength", "go_cellular_component": "GO:0016020 membrane;GO:0031012 extracellular matrix;GO:0005604 basement membrane;GO:0030056 hemidesmosome", "go_biological_process": "GO:0030198 extracellular matrix organization;GO:0031581 hemidesmosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A6QPB3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6H730-1", "uniprot_id": "PPAP_BOVIN", "mass": 44622.0, "length": 387, "protein_name": "Prostatic acid phosphatase", "gene_name": "ACP3", "organism": "Bovine", "refseq_name": "prostatic acid phosphatase precursor", "refseq_ac": "NP_001092336", "gene_names_uniprotkb": "ACP3; ACPP", "gene_names_refseq": "ACP3; ACPP", "protein_names_uniprotkb": "Prostatic acid phosphatase; 3.1.3.2; 3.1.3.48; 3.1.3.5; 5'-NT; 5'-nucleotidase; Acid phosphatase 3; Ecto-5'-nucleotidase; FRAP; Fluoride-resistant acid phosphatase; Protein tyrosine phosphatase ACP3; TMPase; Thiamine monophosphatase", "protein_names_refseq": "Prostatic acid phosphatase; acid phosphatase, prostate; prostatic acid phosphatase precursor; protein tyrosine phosphatase ACP3", "tax_id": 9913, "disease": "", "pathway": " (bta:504700); (R-BTA-6798695)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma (By similarity)., [UniProtKB, UniProtKB]; In addition to its tyrosine phosphatase activity, also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP. This extracellular adenosine leads to a decrease in chronic pain by activating A1R in nociceptive neurons., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0AAA9TYN9", "ec_number_list": "3.5.1.92;7.6.2.1;3.1.3.1;3.1.3.48;3.1.3.16;3.1.3.5;3.1.3.91;3.1.3.89;3.1.3.99;3.1.3.35;3.6.5.2;3.1.3.2;3.2.1.25;3.4.16.2;3.1.3.4;3.1.3.106;3.6.1.75;3.1.3.67;3.1.3.21;2.5.1.18;2.7.1.77;2.4.1.-;2.4.1.275;2.4.1.22;2.4.1.38;2.4.1.90;3.9.1.1;3.1.3.18;3.2.1.20;3.4.23.-", "go_molecular_function": "GO:0052642 lysophosphatidic acid phosphatase activity;GO:0008253 5'-nucleotidase activity;GO:0003993 acid phosphatase activity;GO:0042131 thiamine phosphate phosphatase activity;GO:0016791 phosphatase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0012506 vesicle membrane;GO:0030175 filopodium", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0046085 adenosine metabolic process;GO:0051930 regulation of sensory perception of pain;GO:0006772 thiamine metabolic process;GO:0060168 positive regulation of adenosine receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6H730-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A4FV08-1", "uniprot_id": "GNPI1_BOVIN", "mass": 32580.0, "length": 289, "protein_name": "Glucosamine-6-phosphate deaminase 1", "gene_name": "GNPDA1", "organism": "Bovine", "refseq_name": "glucosamine-6-phosphate deaminase 1", "refseq_ac": "NP_001073756", "gene_names_uniprotkb": "GNPDA1; GNPI", "gene_names_refseq": "GNPDA1; GNPI", "protein_names_uniprotkb": "Glucosamine-6-phosphate deaminase 1; 3.5.99.6; GlcN6P deaminase 1; Glucosamine-6-phosphate isomerase 1; Protein oscillin", "protein_names_refseq": "GNPDA 1; glcN6P deaminase 1; glucosamine-6-phosphate deaminase 1; glucosamine-6-phosphate isomerase 1; oscillin; protein oscillin", "tax_id": 9913, "disease": "", "pathway": " (bta:522919); (R-BTA-70171)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "9774701", "class_list": "", "function": "Catalyzes the reversible conversion of alpha-D-glucosamine 6-phosphate (GlcN-6P) into beta-D-fructose 6-phosphate (Fru-6P) and ammonium ion, a regulatory reaction step in de novo uridine diphosphate-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc) biosynthesis via hexosamine pathway. Deamination is coupled to aldo-keto isomerization mediating the metabolic flux from UDP-GlcNAc toward Fru-6P. At high ammonium level can drive amination and isomerization of Fru-6P toward hexosamines and UDP-GlcNAc synthesis. Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and their effects on hyaluronan synthesis that occur during tissue remodeling. Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.99.6", "go_molecular_function": "GO:0004342 glucosamine-6-phosphate deaminase activity;GO:0042802 identical protein binding;GO:0016853 isomerase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006043 glucosamine catabolic process;GO:0006046 N-acetylglucosamine catabolic process;GO:0005975 carbohydrate metabolic process;GO:0006048 UDP-N-acetylglucosamine biosynthetic process;GO:0019262 N-acetylneuraminate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A4FV08-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5PJS6-1", "uniprot_id": "UBP10_BOVIN", "mass": 86532.0, "length": 800, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10", "gene_name": "USP10", "organism": "Bovine", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 10", "refseq_ac": "NP_001092394", "gene_names_uniprotkb": "USP10", "gene_names_refseq": "USP10", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 10; 3.4.19.12; Deubiquitinating enzyme 10; Ubiquitin thioesterase 10; Ubiquitin-specific-processing protease 10", "protein_names_refseq": "deubiquitinating enzyme 10; ubiquitin carboxyl-terminal hydrolase 10; ubiquitin thioesterase 10; ubiquitin thiolesterase 10; ubiquitin-specific-processing protease 10", "tax_id": 9913, "disease": "", "pathway": " (bta:510164)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB, UniProtKB]; Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, RPS2/us5, RPS3/us3, RPS10/eS10, BECN1, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Component of a regulatory loop that controls autophagy and p53/TP53 levels: mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. In turn, PIK3C3/VPS34-containing complexes regulate USP10 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13. Does not deubiquitinate MDM2. Plays a key role in 40S ribosome subunit recycling when a ribosome has stalled during translation: acts both by inhibiting formation of stress granules, which store stalled translation pre-initiation complexes, and mediating deubiquitination of 40S ribosome subunits. Acts as a negative regulator of stress granules formation by lowering G3BP1 and G3BP2 valence, thereby preventing G3BP1 and G3BP2 ability to undergo liquid-liquid phase separation (LLPS) and assembly of stress granules. Promotes 40S ribosome subunit recycling following ribosome dissociation in response to ribosome stalling by mediating deubiquitination of 40S ribosomal proteins RPS2/us5, RPS3/us3 and RPS10/eS10, thereby preventing their degradation by the proteasome. Part of a ribosome quality control that takes place when ribosomes have stalled during translation initiation (iRQC): USP10 acts by removing monoubiquitination of RPS2/us5 and RPS3/us3, promoting 40S ribosomal subunit recycling. Deubiquitinates CFTR in early endosomes, enhancing its endocytic recycling. Involved in a TANK-dependent negative feedback response to attenuate NF-kappa-B activation via deubiquitinating IKBKG or TRAF6 in response to interleukin-1-beta (IL1B) stimulation or upon DNA damage. Deubiquitinates TBX21 leading to its stabilization. Plays a negative role in the RLR signaling pathway upon RNA virus infection by blocking the RIGI-mediated MAVS activation. Mechanistically, removes the unanchored 'Lys-63'-linked polyubiquitin chains of MAVS to inhibit its aggregation, essential for its activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0044325 transmembrane transporter binding;GO:0002039 p53 binding;GO:0004197 cysteine-type endopeptidase activity;GO:0004843 cysteine-type deubiquitinase activity;GO:0140678 molecular function inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005769 early endosome;GO:0032991 protein-containing complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0006281 DNA repair;GO:0006508 proteolysis;GO:0010506 regulation of autophagy;GO:0016579 protein deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A5PJS6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1A4I4-1", "uniprot_id": "PKN1_BOVIN", "mass": 104133.0, "length": 944, "protein_name": "Serine/threonine-protein kinase N1", "gene_name": "PKN1", "organism": "Bovine", "refseq_name": "serine/threonine-protein kinase N1", "refseq_ac": "NP_001073715", "gene_names_uniprotkb": "PKN1; PKN; PRK1; PRKCL1", "gene_names_refseq": "PKN1", "protein_names_uniprotkb": "Serine/threonine-protein kinase N1; 2.7.11.13; Protein kinase C-like 1; Protein kinase C-like PKN; Protein kinase PKN-alpha; Protein-kinase C-related kinase 1; Serine-threonine protein kinase N", "protein_names_refseq": "protein kinase C-like 1; protein kinase C-like PKN; protein kinase PKN-alpha; protein-kinase C-related kinase 1; serine-threonine protein kinase N; serine/threonine-protein kinase N1", "tax_id": 9913, "disease": "", "pathway": " (bta:509080); (R-BTA-5625740); (R-BTA-5625886); (R-BTA-8980692); (R-BTA-9013106)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "PKC-related serine/threonine-protein kinase involved in various processes such as regulation of the intermediate filaments of the actin cytoskeleton, cell migration, tumor cell invasion and transcription regulation. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. Regulates the cytoskeletal network by phosphorylating proteins such as VIM and neurofilament proteins NEFH, NEFL and NEFM, leading to inhibit their polymerization. Phosphorylates 'Ser-575', 'Ser-637' and 'Ser-669' of MAPT/Tau, lowering its ability to bind to microtubules, resulting in disruption of tubulin assembly. Acts as a key coactivator of androgen receptor (ANDR)-dependent transcription, by being recruited to ANDR target genes and specifically mediating phosphorylation of 'Thr-11' of histone H3 (H3T11ph), a specific tag for epigenetic transcriptional activation that promotes demethylation of histone H3 'Lys-9' (H3K9me) by KDM4C/JMJD2C. Phosphorylates HDAC5, HDAC7 and HDAC9, leading to impair their import in the nucleus. Phosphorylates 'Thr-38' of PPP1R14A, 'Ser-159', 'Ser-163' and 'Ser-170' of MARCKS, and GFAP. Able to phosphorylate RPS6 in vitro., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;3.1.4.4;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;1.14.11.66;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;1.14.14.18;3.1.3.48;1.14.11.65;1.14.99.66;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;3.6.5.2;2.7.11.-;2.7.11.4;2.7.2.3;3.6.4.-;2.7.11.10", "go_molecular_function": "GO:0035402 histone H3T11 kinase activity;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005768 endosome;GO:0032154 cleavage furrow;GO:0030496 midbody", "go_biological_process": "GO:0010631 epithelial cell migration;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006468 protein phosphorylation;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A1A4I4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1B8E6-1", "uniprot_id": "E1B8E6_BOVIN", "mass": 72076.0, "length": 650, "protein_name": "BCL6 transcription repressor", "gene_name": "BCL6", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "BCL6", "gene_names_refseq": "", "protein_names_uniprotkb": "BCL6 transcription repressor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:539020)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005657 replication fork;GO:0042382 paraspeckles;GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006954 inflammatory response;GO:0043065 positive regulation of apoptotic process;GO:0006974 DNA damage response;GO:0030308 negative regulation of cell growth", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1B8E6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BPQ4-1", "uniprot_id": "E1BPQ4_BOVIN", "mass": 11832.0, "length": 109, "protein_name": "High mobility group AT-hook 2", "gene_name": "HMGA2", "organism": "Bovine", "refseq_name": "high mobility group protein HMGI-C", "refseq_ac": "XP_002687694", "gene_names_uniprotkb": "HMGA2", "gene_names_refseq": "HMGA2", "protein_names_uniprotkb": "High mobility group AT-hook 2", "protein_names_refseq": "high mobility group protein HMGI-C", "tax_id": 9913, "disease": "", "pathway": " (bta:100297155)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0051575 5'-deoxyribose-5-phosphate lyase activity;GO:0003680 minor groove of adenine-thymine-rich DNA binding;GO:0008301 DNA binding, bending;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0032993 protein-DNA complex;GO:0000228 nuclear chromosome;GO:0071141 SMAD protein complex", "go_biological_process": "GO:0010557 positive regulation of macromolecule biosynthetic process;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:2000648 positive regulation of stem cell proliferation;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BPQ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BBQ2-1", "uniprot_id": "MGLYR_BOVIN", "mass": 135363.0, "length": 1216, "protein_name": "Metabotropic glycine receptor", "gene_name": "GPR158", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GPR158", "gene_names_refseq": "", "protein_names_uniprotkb": "Metabotropic glycine receptor; G protein-coupled receptor 158; mGlyR", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:538123)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Metabotropic receptor for glycine that controls synapse formation and function in the brain. Acts as an atypical G protein coupled receptor that recruits and regulates the RGS7-GNB5 complex instead of activating G proteins. In absence of glycine ligand, promotes the GTPase activator activity of RGS7, increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Glycine-binding changes the conformation of the intracellular surface, inhibiting the GTPase activator activity of the RGS7-GNB5 complex, promoting G protein alpha subunits into their active GTP-bound form and regulating cAMP levels. Also able to bind taurine, a compound closely related to glycine, but with a two-fold lower affinity. Glycine receptor-dependent regulation of cAMP controls key ion channels, kinases and neurotrophic factors involved in neuronal excitability and synaptic transmission (By similarity). Plays a pivotal role in regulating mood and cognition via its ability to regulate neuronal excitability in L2/L3 pyramidal neurons of the prefrontal cortex. Also involved in spatial learning by regulating hippocampal CA1 neuronal excitability. Acts as a synaptic organizer in the hippocampus, required for proper mossy fiber-CA3 neurocircuitry establishment, structure and function: induces presynaptic differentiation in contacting axons via its interaction with GPC4. In addition to glycine, may also act as a receptor for osteocalcin (BGLAP) hormone: osteocalcin-binding initiates a signaling response that prevents neuronal apoptosis in the hippocampus and regulates the synthesis of neurotransmitters (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0008047 enzyme activator activity;GO:0160079 G protein-coupled glycine receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0045211 postsynaptic membrane;GO:0042734 presynaptic membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0050890 cognition;GO:0072659 protein localization to plasma membrane;GO:0050807 regulation of synapse organization;GO:0008277 regulation of G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E1BBQ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BPQ1-1", "uniprot_id": "FOXO1_BOVIN", "mass": 66356.0, "length": 624, "protein_name": "Forkhead box protein O1", "gene_name": "FOXO1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FOXO1; FOXO1A", "gene_names_refseq": "", "protein_names_uniprotkb": "Forkhead box protein O1; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:506618); (R-BTA-211163); (R-BTA-5687128); (R-BTA-9614399); (R-BTA-9617629); (R-BTA-9617828)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Also acts as a key regulator of chondrogenic commitment of skeletal progenitor cells in response to lipid availability: when lipids levels are low, translocates to the nucleus and promotes expression of SOX9, which induces chondrogenic commitment and suppresses fatty acid oxidation. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. Acts as an inhibitor of glucose sensing in pancreatic beta cells by acting as a transcription repressor and suppressing expression of PDX1. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC1 and PCK1 (By similarity). Also promotes gluconeogenesis by directly promoting expression of PPARGC1A and G6PC1 (By similarity). Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and STK4/MST1 (By similarity). Promotes neural cell death (By similarity). Mediates insulin action on adipose tissue (By similarity). Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake (By similarity). Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells (By similarity). Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner (By similarity). Mediates the function of MLIP in cardiomyocytes hypertrophy and cardiac remodeling (By similarity). Positive regulator of apoptosis in cardiac smooth muscle cells as a result of its transcriptional activation of pro-apoptotic genes (By similarity). Regulates endothelial cell (EC) viability and apoptosis in a PPIA/CYPA-dependent manner via transcription of CCL2 and BCL2L11 which are involved in EC chemotaxis and apoptosis (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0051721 protein phosphatase 2A binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0032869 cellular response to insulin stimulus;GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E1BPQ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O18778-1", "uniprot_id": "PAHX_BOVIN", "mass": 38770.0, "length": 337, "protein_name": "Phytanoyl-CoA dioxygenase, peroxisomal", "gene_name": "PHYH", "organism": "Bovine", "refseq_name": "phytanoyl-CoA dioxygenase, peroxisomal precursor", "refseq_ac": "NP_776567", "gene_names_uniprotkb": "PHYH; LN1; PAHX", "gene_names_refseq": "PHYH", "protein_names_uniprotkb": "Phytanoyl-CoA dioxygenase, peroxisomal; 1.14.11.18; PhyH; Phytanic acid oxidase; Phytanoyl-CoA alpha-hydroxylase", "protein_names_refseq": "phytanic acid oxidase; phytanoyl-CoA alpha-hydroxylase; phytanoyl-CoA dioxygenase, peroxisomal precursor; phytanoyl-CoA dioxygenase, peroxisomal; phytanoyl-CoA hydroxylase", "tax_id": 9913, "disease": "", "pathway": " (bta:281400); (R-BTA-389599); (R-BTA-9033241)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the 2-hydroxylation of not only racemic phytanoyl-CoA and the isomers of 3-methylhexadecanoyl-CoA, but also a variety of other mono- branched 3-methylacyl-CoA esters (with a chain length of at least seven carbon atoms) and straight-chain acyl-CoA esters (with a chain length longer than four carbon atoms) (By similarity). Does not hydroxylate long and very long straight chain acyl-CoAs or 2-methyl-and 4-methyl-branched acyl-CoAs (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3T0C0", "ec_number_list": "2.3.2.27;2.5.1.26;1.14.11.18", "go_molecular_function": "GO:0046872 metal ion binding;GO:0031418 L-ascorbic acid binding;GO:0048244 phytanoyl-CoA dioxygenase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0001561 fatty acid alpha-oxidation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "O18778-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MH07-1", "uniprot_id": "MICA1_BOVIN", "mass": 118696.0, "length": 1070, "protein_name": "[F-actin]-monooxygenase MICAL1", "gene_name": "MICAL1", "organism": "Bovine", "refseq_name": "[F-actin]-monooxygenase MICAL1", "refseq_ac": "NP_001075051", "gene_names_uniprotkb": "MICAL1", "gene_names_refseq": "MICAL-1; MICAL1", "protein_names_uniprotkb": "[F-actin]-monooxygenase MICAL1; 1.14.13.225; 1.6.3.1; MICAL-1; Molecule interacting with CasL protein 1", "protein_names_refseq": "[F-actin]-methionine sulfoxide oxidase MICAL1; [F-actin]-monooxygenase MICAL1; microtubule associated monoxygenase, calponin and LIM domain containing 1; molecule interacting with CasL protein 1; protein-methionine sulfoxide oxidase MICAL1", "tax_id": 9913, "disease": "", "pathway": " (bta:508306)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization. In the absence of actin, it also functions as a NADPH oxidase producing H(2)O(2). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4. Involved in regulation of lamina-specific connectivity in the nervous system such as the development of lamina-restricted hippocampal connections. Through redox regulation of the actin cytoskeleton controls the intracellular distribution of secretory vesicles containing L1/neurofascin/NgCAM family proteins in neurons, thereby regulating their cell surface levels. May act as Rab effector protein and play a role in vesicle trafficking. Promotes endosomal tubule extension by associating with RAB8 (RAB8A or RAB8B), RAB10 and GRAF (GRAF1/ARHGAP26 or GRAF2/ARHGAP10) on the endosomal membrane which may connect GRAFs to Rabs, thereby participating in neosynthesized Rab8-Rab10-Rab11-dependent protein export (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A2VDL7", "ec_number_list": "1.6.99.1;1.6.3.1;1.14.13.225", "go_molecular_function": "GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0003779 actin binding;GO:0046872 metal ion binding;GO:0071949 FAD binding;GO:0016174 NAD(P)H oxidase H2O2-forming activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0019417 sulfur oxidation;GO:0030042 actin filament depolymerization;GO:0043066 negative regulation of apoptotic process;GO:1903305 regulation of regulated secretory pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MH07-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5PK46-1", "uniprot_id": "LIPR2_BOVIN", "mass": 52193.0, "length": 469, "protein_name": "Pancreatic lipase-related protein 2", "gene_name": "PNLIPRP2", "organism": "Bovine", "refseq_name": "pancreatic lipase-related protein 2 precursor", "refseq_ac": "NP_001098825", "gene_names_uniprotkb": "PNLIPRP2", "gene_names_refseq": "PL-RP2; PNLIPRP2", "protein_names_uniprotkb": "Pancreatic lipase-related protein 2; 3.1.1.26; 3.1.1.3; Cytotoxic T lymphocyte lipase; Galactolipase; PL-RP2; Triacylglycerol lipase", "protein_names_refseq": "cytotoxic T lymphocyte lipase; galactolipase; pancreatic lipase-related protein 2 precursor; triacylglycerol lipase", "tax_id": 9913, "disease": "", "pathway": " (bta:510772); (R-BTA-192456)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Lipase that primarily hydrolyzes triglycerides and galactosylglycerides. In neonates, may play a major role in pancreatic digestion of dietary fats such as milk fat globules enriched in long-chain triglycerides. Hydrolyzes short-, medium- and long-chain fatty acyls in triglycerides without apparent positional specificity. Can completely deacylate triacylglycerols. When the liver matures and bile salt synthesis increases, likely functions mainly as a galactolipase and monoacylglycerol lipase. Hydrolyzes monogalactosyldiglycerols (MGDG) and digalactosyldiacylglycerols (DGDG) present in a plant-based diet, releasing long-chain polyunsaturated fatty acids. Hydrolyzes medium- and long-chain fatty acyls in galactolipids. May act together with LIPF to hydrolyze partially digested triglycerides. Hydrolyzes long-chain monoglycerides with high efficiency (By similarity). In cytotoxic T cells, contributes to perforin-dependent cell lysis, but is unlikely to mediate direct cytotoxicity (By similarity). Also has low phospholipase activity (By similarity). In neurons, required for the localization of the phospholipid 1-oleoyl-2-palmitoyl-PC (OPPC) to neurite tips through acyl chain remodeling of membrane phospholipids (By similarity). The resulting OPPC-rich lipid membrane domain recruits the t-SNARE protein STX4 by selectively interacting with the STX4 transmembrane domain and this promotes surface expression of the dopamine transporter SLC6A3/DAT at neurite tips by facilitating fusion of SLC6A3-containing transport vesicles with the plasma membrane (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.1.32;3.1.1.3;3.1.1.4;3.1.1.5;3.1.1.23;3.1.1.79;2.3.1.51;3.1.1.26;3.1.1.116;3.1.1.34;3.1.1.13;3.1.1.6;3.1.1.-;3.1.-.-", "go_molecular_function": "GO:0004620 phospholipase activity;GO:0047372 monoacylglycerol lipase activity;GO:0005509 calcium ion binding;GO:0008970 phospholipase A1 activity;GO:0004806 triacylglycerol lipase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0043005 neuron projection;GO:0042589 zymogen granule membrane;GO:0005576 extracellular region", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0009395 phospholipid catabolic process;GO:0034375 high-density lipoprotein particle remodeling;GO:0042632 cholesterol homeostasis;GO:0019433 triglyceride catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A5PK46-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6QNM7-1", "uniprot_id": "UBP33_BOVIN", "mass": 103323.0, "length": 912, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33", "gene_name": "USP33", "organism": "Bovine", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 33", "refseq_ac": "NP_001094609", "gene_names_uniprotkb": "USP33", "gene_names_refseq": "USP33", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 33; 3.4.19.12; Deubiquitinating enzyme 33; Ubiquitin thioesterase 33; Ubiquitin-specific-processing protease 33", "protein_names_refseq": "deubiquitinating enzyme 33; ubiquitin carboxyl-terminal hydrolase 33; ubiquitin specific protease 33; ubiquitin thioesterase 33; ubiquitin thiolesterase 33; ubiquitin-specific-processing protease 33", "tax_id": 9913, "disease": "", "pathway": " (bta:531706); (R-BTA-5689880); (R-BTA-9010553)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Deubiquitinating enzyme involved in various processes such as centrosome duplication, cellular migration and beta-2 adrenergic receptor/ADRB2 recycling. Involved in regulation of centrosome duplication by mediating deubiquitination of CCP110 in S and G2/M phase, leading to stabilize CCP110 during the period which centrioles duplicate and elongate. Involved in cell migration via its interaction with intracellular domain of ROBO1, leading to regulate the Slit signaling. Plays a role in commissural axon guidance cross the ventral midline of the neural tube in a Slit-dependent manner, possibly by mediating the deubiquitination of ROBO1. Acts as a regulator of G protein-coupled receptor (GPCR) signaling by mediating the deubiquitination of beta-arrestins (ARRB1 and ARRB2) and beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity)., [UniProtKB]; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.19.12", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004197 cysteine-type endopeptidase activity;GO:0004843 cysteine-type deubiquitinase activity;GO:0001664 G protein-coupled receptor binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005813 centrosome;GO:0048471 perinuclear region of cytoplasm;GO:0005794 Golgi apparatus;GO:0044297 cell body", "go_biological_process": "GO:0006508 proteolysis;GO:0006897 endocytosis;GO:0007399 nervous system development;GO:0016477 cell migration;GO:0016579 protein deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6QNM7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O46411-1", "uniprot_id": "5NTC_BOVIN", "mass": 64841.0, "length": 560, "protein_name": "Cytosolic purine 5'-nucleotidase", "gene_name": "NT5C2", "organism": "Bovine", "refseq_name": "cytosolic purine 5'-nucleotidase", "refseq_ac": "NP_776830", "gene_names_uniprotkb": "NT5C2", "gene_names_refseq": "NT5C2", "protein_names_uniprotkb": "Cytosolic purine 5'-nucleotidase; 2.7.1.77; 3.1.3.5; 3.1.3.99; Cytosolic IMP/GMP-specific 5'-nucleotidase; Cytosolic nucleoside phosphotransferase 5'N", "protein_names_refseq": "cytosolic 5'-nucleotidase II; cytosolic IMP/GMP-specific 5'-nucleotidase; cytosolic nucleoside phosphotransferase 5'N; cytosolic purine 5'-nucleotidase", "tax_id": 9913, "disease": "", "pathway": " (bta:281951); (R-BTA-2161541); (R-BTA-74259); (R-BTA-9755088)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "21029378;33477638;8031149;9371705", "class_list": "", "function": "Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates. In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside, preferably inosine, deoxyinosine and guanosine. Has the highest activities for IMP and GMP followed by dIMP, dGMP and XMP. Could also catalyze the transfer of phosphates from pyrimidine monophosphates but with lower efficiency. Through these activities regulates the purine nucleoside/nucleotide pools within the cell., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, PubMed, PubMed]; Cytosolic 5'-Nucleotidase II Is a Sensor of Energy Charge and Oxidative Stress: A Possible Function as Metabolic Regulator. Publication Status: Online-Only, [RefSeq, PubMed]; Mutated three residues that mediate interaction in the first activation site (R144, N154, I152) and three in the second (F127, M436 and H428), and found that ApA and ADP interact with the same site, but the sites for ATP and BPG remain uncertain, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.5;3.1.3.91;3.1.3.89;3.1.3.99;3.1.3.35;3.1.3.2;3.1.3.48;2.7.1.77;3.6.1.-;3.1.4.1;3.6.1.9", "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0008253 5'-nucleotidase activity;GO:0050146 nucleoside phosphotransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0046054 dGMP metabolic process;GO:0046037 GMP metabolic process;GO:0046040 IMP metabolic process;GO:0046085 adenosine metabolic process;GO:0050689 negative regulation of defense response to virus by host", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "O46411-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O62829-1", "uniprot_id": "PPM1A_BOVIN", "mass": 42530.0, "length": 382, "protein_name": "Protein phosphatase 1A", "gene_name": "PPM1A", "organism": "Bovine", "refseq_name": "protein phosphatase 1A isoform 1", "refseq_ac": "NP_001289701", "gene_names_uniprotkb": "PPM1A", "gene_names_refseq": "PP2C-alpha; PPM1A", "protein_names_uniprotkb": "Protein phosphatase 1A; 3.1.3.16; PP2C-alpha; Protein phosphatase 2C isoform alpha", "protein_names_refseq": "protein phosphatase 1A isoform 1; protein phosphatase 1A", "tax_id": 9913, "disease": "", "pathway": " (bta:281994); (R-BTA-2173795); (R-BTA-380972)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "9486768", "class_list": "", "function": "Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.16;3.1.3.48;2.7.11.1;2.7.11.31;3.1.3.67;2.7.11.26;3.1.3.74;3.1.3.52;3.1.3.53", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0030145 manganese ion binding;GO:0004722 protein serine/threonine phosphatase activity;GO:0070412 R-SMAD binding;GO:0004721 phosphoprotein phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0043124 negative regulation of canonical NF-kappaB signal transduction;GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction;GO:0006470 protein dephosphorylation;GO:0090263 positive regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O62829-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01180-1", "uniprot_id": "NEU2_BOVIN", "mass": 17325.0, "length": 166, "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "organism": "Bovine", "refseq_name": "vasopressin-neurophysin 2-copeptin preproprotein", "refseq_ac": "NP_789824", "gene_names_uniprotkb": "AVP", "gene_names_refseq": "AVP-NPII; AVP", "protein_names_uniprotkb": "Vasopressin-neurophysin 2-copeptin; AVP-NPII; Arginine-vasopressin; Neurophysin-II", "protein_names_refseq": "arginine vasopressin (neurophysin II, antidiuretic hormone, diabetes insipidus, neurohypophyseal); arginine vasopressin-neurophysin II; neurophysin II; vasopressin-neurophysin 2-copeptin preproprotein; vasopressin-neurophysin 2-copeptin", "tax_id": 9913, "disease": "", "pathway": " (bta:280728); (R-BTA-388479); (R-BTA-416476); (R-BTA-418555); (R-BTA-432040); (R-BTA-879518); (R-BTA-8856825); (R-BTA-8856828)", "pathway_count": 8, "publication_count": 20, "publication_id_list": "1150656;11514677;1248642;1252249;13115463;1551883;2034668;3318825;3417672;3768139;4564211;465021;5094666;6276766;6709064;7061422;7138841;7204368;8564543;932015", "class_list": "", "function": "Carrier protein that binds to and transports Arg-vasopressin from the hypothalamus to the posterior pituitary gland, protecting it from degradation and facilitating its release., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]; Has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels. Acts by binding to vasopressin receptors (V1bR/AVPR1B, V1aR/AVPR1A, and V2R/AVPR2)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Precursor of Arg-vasopressin, an antidiuretic hormone, and neurophysin 2, its carrier protein., [UniProtKB, PubMed]; Specifically binds vasopressin., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q3SZF1", "ec_number_list": "", "go_molecular_function": "GO:0005185 neurohypophyseal hormone activity;GO:0031894 V1A vasopressin receptor binding;GO:0005184 neuropeptide hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0030141 secretory granule;GO:0005576 extracellular region", "go_biological_process": "GO:0002125 maternal aggressive behavior;GO:0035556 intracellular signal transduction;GO:0003084 positive regulation of systemic arterial blood pressure;GO:0045907 positive regulation of vasoconstriction;GO:0042310 vasoconstriction", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P01180-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G5E5J5-1", "uniprot_id": "G5E5J5_BOVIN", "mass": 48203.0, "length": 425, "protein_name": "Vitamin D3 receptor", "gene_name": "VDR", "organism": "Bovine", "refseq_name": "vitamin D3 receptor", "refseq_ac": "NP_001161404", "gene_names_uniprotkb": "VDR", "gene_names_refseq": "VDR", "protein_names_uniprotkb": "Vitamin D3 receptor; 1,25-dihydroxyvitamin D3 receptor; Nuclear receptor subfamily 1 group I member 1", "protein_names_refseq": "1,25-dihydroxyvitamin D3 receptor; nuclear receptor subfamily 1 group I member 1; vitamin D (1,25- dihydroxyvitamin D3) receptor; vitamin D receptor protein; vitamin D3 receptor", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-196791); (R-BTA-383280); (R-BTA-4090294)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "21414188;23981931", "class_list": "", "function": "Two novel SNPs identified in coding region of VDR are associated with growth traits. Publication Status: Online-Only, [RefSeq, PubMed]; Vitamin D receptor activation, and inducible nitric oxide synthase (NOS2), were strongly induced during Cooperia oncophora reinfection. Several canonical pathways associated with NOS2 were impacted. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0046965 nuclear retinoid X receptor binding;GO:0038186 bile acid nuclear receptor activity;GO:1902098 calcitriol binding;GO:1902121 lithocholic acid binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0043235 receptor complex;GO:0000785 chromatin;GO:0090575 RNA polymerase II transcription regulator complex;GO:0005634 nucleus", "go_biological_process": "GO:0070561 vitamin D receptor signaling pathway;GO:0038185 nuclear receptor-mediated bile acid signaling pathway;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "G5E5J5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A7MBI7-1", "uniprot_id": "COMT_BOVIN", "mass": 30485.0, "length": 272, "protein_name": "Catechol O-methyltransferase", "gene_name": "COMT", "organism": "Bovine", "refseq_name": "catechol O-methyltransferase", "refseq_ac": "NP_001095787", "gene_names_uniprotkb": "COMT", "gene_names_refseq": "COMT", "protein_names_uniprotkb": "Catechol O-methyltransferase; 2.1.1.6", "protein_names_refseq": "catechol O-methyltransferase", "tax_id": 9913, "disease": "", "pathway": " (bta:618278); (R-BTA-156581); (R-BTA-379397); (R-BTA-379398)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.6", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0016206 catechol O-methyltransferase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0032502 developmental process;GO:0042417 dopamine metabolic process;GO:0032259 methylation;GO:0042424 catecholamine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A7MBI7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLX5-1", "uniprot_id": "LGR4_BOVIN", "mass": 104466.0, "length": 951, "protein_name": "Leucine-rich repeat-containing G protein-coupled receptor 4", "gene_name": "LGR4", "organism": "Bovine", "refseq_name": "leucine-rich repeat-containing G-protein coupled receptor 4 precursor", "refseq_ac": "NP_001192440", "gene_names_uniprotkb": "LGR4", "gene_names_refseq": "LGR4", "protein_names_uniprotkb": "Leucine-rich repeat-containing G protein-coupled receptor 4", "protein_names_refseq": "leucine-rich repeat-containing G-protein coupled receptor 4 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:505423)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "19393038;34139630", "class_list": "", "function": "MiR-193a-3p targets LGR4 to promote the inflammatory response in endometritis., [RefSeq, PubMed]; Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G protein-coupled receptors, does not activate heterotrimeric G proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye. May also act as a receptor for norrin (NDP), such results however required additional confirmation in vivo. Required during spermatogenesis to activate the Wnt signaling pathway in peritubular myoid cells. Required for the maintenance of intestinal stem cells and Paneth cell differentiation in postnatal intestinal crypts. Acts as a regulator of bone formation and remodeling. Involved in kidney development; required for maintaining the ureteric bud in an undifferentiated state. Involved in the development of the anterior segment of the eye. Required during erythropoiesis. Also acts as a negative regulator of innate immunity by inhibiting TLR2/TLR4 associated pattern-recognition and pro-inflammatory cytokine production. Plays an important role in regulating the circadian rhythms of plasma lipids, partially through regulating the rhythmic expression of MTTP. Required for proper development of GnRH neurons (gonadotropin-releasing hormone expressing neurons) that control the release of reproductive hormones from the pituitary gland (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016500 protein-hormone receptor activity;GO:0004888 transmembrane signaling receptor activity;GO:0038023 signaling receptor activity;GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007283 spermatogenesis;GO:0045087 innate immune response;GO:0046849 bone remodeling;GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1MLX5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T881-1", "uniprot_id": "A0A140T881_BOVIN", "mass": 37194.0, "length": 326, "protein_name": "Apolipoprotein E", "gene_name": "APOE", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "APOE", "gene_names_refseq": "", "protein_names_uniprotkb": "Apolipoprotein E", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-381426); (R-BTA-8957275); (R-BTA-8963888); (R-BTA-8963901); (R-BTA-8964026); (R-BTA-8964058); (R-BTA-975634)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005543 phospholipid binding;GO:0008201 heparin binding;GO:0019899 enzyme binding;GO:0042803 protein homodimerization activity;GO:0043395 heparan sulfate proteoglycan binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0031012 extracellular matrix;GO:0034363 intermediate-density lipoprotein particle", "go_biological_process": "GO:0050709 negative regulation of protein secretion;GO:0006641 triglyceride metabolic process;GO:0007186 G protein-coupled receptor signaling pathway;GO:0008203 cholesterol metabolic process;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T881-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N780-1", "uniprot_id": "F1N780_BOVIN", "mass": 112038.0, "length": 998, "protein_name": "Ephrin type-A receptor 7", "gene_name": "EPHA7", "organism": "Bovine", "refseq_name": "ephrin type-A receptor 7 isoform X1", "refseq_ac": "XP_024852545", "gene_names_uniprotkb": "EPHA7", "gene_names_refseq": "EPHA7", "protein_names_uniprotkb": "Ephrin type-A receptor 7; 2.7.10.1; EPH homology kinase 3", "protein_names_refseq": "ephrin type-A receptor 7 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:538797); (R-BTA-2682334); (R-BTA-3928663); (R-BTA-3928665)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.1;3.6.5.2;2.7.10.4", "go_molecular_function": "GO:0005524 ATP binding;GO:0005003 ephrin receptor activity;GO:0019838 growth factor binding;GO:0045499 chemorepellent activity;GO:0005005 transmembrane-ephrin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098978 glutamatergic synapse;GO:0030425 dendrite", "go_biological_process": "GO:0048013 ephrin receptor signaling pathway;GO:0022407 regulation of cell-cell adhesion;GO:0007420 brain development;GO:0050804 modulation of chemical synaptic transmission;GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N780-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O46522-1", "uniprot_id": "CY24B_BOVIN", "mass": 65643.0, "length": 570, "protein_name": "NADPH oxidase 2", "gene_name": "CYBB", "organism": "Bovine", "refseq_name": "NADPH oxidase 2", "refseq_ac": "NP_776460", "gene_names_uniprotkb": "CYBB", "gene_names_refseq": "CYBB; NOX2", "protein_names_uniprotkb": "NADPH oxidase 2; 1.6.3.-; CGD91-phox; Cytochrome b(558) subunit beta; Cytochrome b-245 heavy chain; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; Neutrophil cytochrome b 91 kDa polypeptide; gp91-1; gp91-phox; p22 phagocyte B-cytochrome", "protein_names_refseq": "CGD91-phox; NADPH oxidase 2; cytochrome b(558) subunit beta; cytochrome b-245 heavy chain; cytochrome b-245, beta polypeptide; cytochrome b558 subunit beta; gp91-1; gp91-phox; heme-binding membrane glycoprotein gp91phox; neutrophil cytochrome b 91 kDa polypeptide; p22 phagocyte B-cytochrome", "tax_id": 9913, "disease": "", "pathway": " (bta:281112); (R-BTA-1222556); (R-BTA-1236973); (R-BTA-3299685); (R-BTA-4420097); (R-BTA-5668599); (R-BTA-6798695); (R-BTA-9013404); (R-BTA-9013423)", "pathway_count": 9, "publication_count": 3, "publication_id_list": "19168729;25448770;9665285", "class_list": "", "function": "A p47(phox) and Src kinase activation of peroxide production by Nox2 appears to be an important contributor to vascular contractile mechanisms mediated through activation of protein kinase C, [RefSeq, PubMed]; Catalytic subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)). In the activated complex, electrons are first transferred from NADPH to flavin adenine dinucleotide (FAD) and subsequently transferred via two heme molecules to molecular oxygen, producing superoxide through an outer-sphere reaction. Activation of the NADPH oxidase complex is initiated by the assembly of cytosolic subunits of the NADPH oxidase complex with the core NADPH oxidase complex to form a complex at the plasma membrane or phagosomal membrane (By similarity). This activation process is initiated by phosphorylation dependent binding of the cytosolic NCF1/p47-phox subunit to the C-terminus of CYBA/p22-phox (By similarity). NADPH oxidase complex assembly is impaired through interaction with NRROS (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Data indicate that the efficiency of NADPH oxidase enzymatic activity is higher at endoplasmic reticulum (ER)., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A4IF96", "ec_number_list": "3.1.4.4;2.7.11.1;3.1.3.48;7.6.2.1;3.6.5.2;2.3.1.51;1.14.14.18;2.7.10.1;3.2.2.6;6.2.1.3;1.6.3.1;1.6.3.-;3.4.21.73;3.4.24.81;1.2.1.5;1.2.1.28;1.2.1.7;1.2.1.48;1.1.1.-;1.14.19.17;5.2.1.-;3.2.1.20", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0046982 protein heterodimerization activity;GO:0071949 FAD binding;GO:0020037 heme binding", "go_cellular_component": "GO:0043020 NADPH oxidase complex;GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0005764 lysosome;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0006952 defense response;GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0034220 monoatomic ion transmembrane transport;GO:0045730 respiratory burst", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "O46522-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1B8X8-1", "uniprot_id": "E1B8X8_BOVIN", "mass": 384355.0, "length": 3427, "protein_name": "BRCA2 DNA repair associated", "gene_name": "BRCA2", "organism": "Bovine", "refseq_name": "breast cancer type 2 susceptibility protein", "refseq_ac": "XP_002691853", "gene_names_uniprotkb": "BRCA2", "gene_names_refseq": "BRCA2", "protein_names_uniprotkb": "BRCA2 DNA repair associated", "protein_names_refseq": "breast cancer type 2 susceptibility protein", "tax_id": 9913, "disease": "", "pathway": " (bta:507069); (R-BTA-5685939); (R-BTA-5685942); (R-BTA-5693537); (R-BTA-5693568); (R-BTA-5693579); (R-BTA-5693616)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0002020 protease binding;GO:0042802 identical protein binding;GO:0003697 single-stranded DNA binding;GO:0043015 gamma-tubulin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005654 nucleoplasm;GO:0030141 secretory granule;GO:0000800 lateral element", "go_biological_process": "GO:0000724 double-strand break repair via homologous recombination;GO:0006355 regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0070200 establishment of protein localization to telomere;GO:0051298 centrosome duplication", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1B8X8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1B7Q6-1", "uniprot_id": "E1B7Q6_BOVIN", "mass": 167794.0, "length": 1575, "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "organism": "Bovine", "refseq_name": "mediator of RNA polymerase II transcription subunit 1", "refseq_ac": "NP_001192805", "gene_names_uniprotkb": "MED1", "gene_names_refseq": "MED1", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 1; Mediator complex subunit 1", "protein_names_refseq": "mediator of RNA polymerase II transcription subunit 1", "tax_id": 9913, "disease": "", "pathway": " (bta:520734); (R-BTA-212436); (R-BTA-383280); (R-BTA-400206); (R-BTA-9018519); (R-BTA-9707564); (R-BTA-9841922)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003712 transcription coregulator activity;GO:0050693 LBD domain binding;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0016592 mediator complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:2001141 regulation of RNA biosynthetic process;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1B7Q6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MNN7-1", "uniprot_id": "F1MNN7_BOVIN", "mass": 59964.0, "length": 540, "protein_name": "Lipopolysaccharide-binding protein", "gene_name": "LBP", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LBP", "gene_names_refseq": "", "protein_names_uniprotkb": "Lipopolysaccharide-binding protein; LBP", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-166016); (R-BTA-166020); (R-BTA-5686938)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001530 lipopolysaccharide binding;GO:0005102 signaling receptor binding;GO:0015026 coreceptor activity;GO:0071723 lipopeptide binding;GO:0070891 lipoteichoic acid binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface", "go_biological_process": "GO:0006869 lipid transport;GO:0045087 innate immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0043032 positive regulation of macrophage activation;GO:0050830 defense response to Gram-positive bacterium", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MNN7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00432-1", "uniprot_id": "CATA_BOVIN", "mass": 59915.0, "length": 527, "protein_name": "Catalase", "gene_name": "CAT", "organism": "Bovine", "refseq_name": "catalase", "refseq_ac": "NP_001030463", "gene_names_uniprotkb": "CAT", "gene_names_refseq": "CAT", "protein_names_uniprotkb": "Catalase; 1.11.1.6", "protein_names_refseq": "catalase", "tax_id": 9913, "disease": "", "pathway": " (bta:531682); (R-BTA-3299685); (R-BTA-6798695); (R-BTA-9033241)", "pathway_count": 4, "publication_count": 10, "publication_id_list": "10417406;10691967;28613393;28668706;28768117;30573663;33460658;3712444;7082009;7328661", "class_list": "", "function": "Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, PubMed]; Enzyme activity assay and molecular docking revealed that the activity of CAT was slightly inhibited in the presence of Sudan dyes. In comparison, the binding of Sudan II with CAT was slightly stronger than Sudan IV. Also, Sudan II and Sudan IV showed a different impact on the microenvironment of aromatic amino acid residues., [RefSeq, PubMed]; Interaction of artemisinin protects the activity of antioxidant enzyme catalase: A biophysical study., [RefSeq, PubMed]; The decrease in accessible surface area and increase in pKa of important lysine residues were considered as predominant factors in decreased glycation of bovine liver catalase by curcumin., [RefSeq, PubMed]; The interactions between cationic surfactants dodecyltrimethylammonium bromide (DTAB) and tetradecyltrimethylammonium bromide (TTAB) with varying alkyl chain lengths and bovine liver catalase (BLC) were examined by various biophysical approaches., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3SZ80", "ec_number_list": "1.1.1.42;2.5.1.18;2.3.1.42;2.7.1.1;5.3.3.21;2.7.11.24;2.3.2.27;2.3.1.137;2.3.1.7;3.2.1.23;2.4.2.1;5.2.1.8;4.1.2.13;3.6.1.6;3.4.21.-;1.1.3.15;1.1.1.35;4.2.1.17;5.3.3.8;1.4.3.3;1.5.3.13;1.3.1.38;3.1.6.14;3.6.4.13;1.1.1.205;2.7.1.11;2.7.11.22;2.7.11.23;2.3.2.26;2.4.1.25;3.2.1.33;4.2.99.18;5.6.2.4;3.6.4.12;3.4.23.5;1.13.11.34;1.13.11.12;6.2.1.3;2.3.1.176;2.3.1.16;2.3.1.155;4.1.2.63;1.14.13.39;3.1.2.2;3.1.2.27;3.1.2.1;3.1.2.11;3.1.2.3;3.1.2.5;3.6.4.6;1.16.3.1;1.11.1.6;3.4.18.1;3.4.22.1;3.6.4.10;3.4.22.27;3.4.24.35;3.6.5.-;3.1.1.47;5.3.2.1;5.3.3.12;3.4.19.1;2.7.1.35;2.4.1.1;3.5.1.23;3.5.1.-;3.4.24.56;3.4.22.52;4.1.3.4;1.5.3.1;1.5.3.7;2.3.3.8;3.4.21.53;5.4.2.11;5.4.2.4;3.3.2.6;3.4.11.4;1.3.3.6;3.4.21.46;2.7.4.6;2.7.13.3;4.1.2.4;5.3.1.9;5.1.3.-;3.6.1.-;2.4.2.7;4.2.1.24", "go_molecular_function": "GO:0019899 enzyme binding;GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004096 catalase activity;GO:0004046 aminoacylase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005777 peroxisome;GO:0005782 peroxisomal matrix;GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0042542 response to hydrogen peroxide;GO:0051781 positive regulation of cell division;GO:0042744 hydrogen peroxide catabolic process;GO:0006979 response to oxidative stress;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P00432-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BNE0-1", "uniprot_id": "E1BNE0_BOVIN", "mass": 89849.0, "length": 780, "protein_name": "Tyrosine-protein kinase", "gene_name": "FER", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FER", "gene_names_refseq": "", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1433557)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.1;2.7.10.4", "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004713 protein tyrosine kinase activity;GO:0008289 lipid binding;GO:0005154 epidermal growth factor receptor binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0010762 regulation of fibroblast migration;GO:0006935 chemotaxis;GO:0007155 cell adhesion;GO:0008284 positive regulation of cell population proliferation;GO:0030335 positive regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BNE0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BFL2-1", "uniprot_id": "E1BFL2_BOVIN", "mass": 173291.0, "length": 1544, "protein_name": "DNA excision repair protein ERCC-6", "gene_name": "ERCC6", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ERCC6", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA excision repair protein ERCC-6; ATP-dependent helicase ERCC6; Cockayne syndrome protein CSB", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5250924); (R-BTA-6781823); (R-BTA-6782135); (R-BTA-6782210); (R-BTA-73762)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0004386 helicase activity;GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0008023 transcription elongation factor complex;GO:0016604 nuclear body;GO:0090734 site of DNA damage", "go_biological_process": "GO:0006281 DNA repair;GO:0097680 double-strand break repair via classical nonhomologous end joining;GO:0006979 response to oxidative stress;GO:0031175 neuron projection development;GO:0006284 base-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BFL2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MCQ0-1", "uniprot_id": "F1MCQ0_BOVIN", "mass": 69924.0, "length": 643, "protein_name": "Uromodulin", "gene_name": "UMOD", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "UMOD", "gene_names_refseq": "", "protein_names_uniprotkb": "Uromodulin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-446203)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability. May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0019864 IgG binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0060170 ciliary membrane", "go_biological_process": "GO:0045087 innate immune response;GO:1990266 neutrophil migration;GO:0072218 metanephric ascending thin limb development;GO:0050829 defense response to Gram-negative bacterium;GO:0007159 leukocyte cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MCQ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0JN54-1", "uniprot_id": "DGKA_BOVIN", "mass": 82672.0, "length": 734, "protein_name": "Diacylglycerol kinase alpha", "gene_name": "DGKA", "organism": "Bovine", "refseq_name": "diacylglycerol kinase alpha", "refseq_ac": "NP_001071328", "gene_names_uniprotkb": "DGKA", "gene_names_refseq": "DGKA", "protein_names_uniprotkb": "Diacylglycerol kinase alpha; 2.7.1.107; 2.7.1.93; DAG kinase alpha; DGK-alpha; Diglyceride kinase alpha", "protein_names_refseq": "DAG kinase alpha; DGK-alpha; diacylglycerol kinase alpha; diacylglycerol kinase, alpha 80kDa; diglyceride kinase alpha", "tax_id": 9913, "disease": "", "pathway": " (bta:506348); (R-BTA-114508)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids. Can also phosphorylate 1-alkyl-2-acylglycerol in vitro as efficiently as diacylglycerol provided it contains an arachidonoyl group. Also involved in the production of alkyl-lysophosphatidic acid, another bioactive lipid, through the phosphorylation of 1-alkyl-2-acetyl glycerol., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.1.107;2.7.1.93", "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0047649 alkylglycerol kinase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0046339 diacylglycerol metabolic process;GO:0046834 lipid phosphorylation;GO:0006654 phosphatidic acid biosynthetic process;GO:0035556 intracellular signal transduction;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0JN54-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MKH8-1", "uniprot_id": "F1MKH8_BOVIN", "mass": 73848.0, "length": 661, "protein_name": "72 kDa type IV collagenase", "gene_name": "MMP2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MMP2", "gene_names_refseq": "", "protein_names_uniprotkb": "72 kDa type IV collagenase; 3.4.24.24; 72 kDa gelatinase; Matrix metalloproteinase-2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1442490); (R-BTA-1474228); (R-BTA-1592389); (R-BTA-3928665); (R-BTA-9009391)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.1;3.4.24.24;3.4.24.7;3.4.24.17;3.4.24.80;3.4.24.35", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0030017 sarcomere", "go_biological_process": "GO:0006508 proteolysis;GO:0007565 female pregnancy;GO:0030574 collagen catabolic process;GO:0048646 anatomical structure formation involved in morphogenesis;GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MKH8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A2VDU3-1", "uniprot_id": "M3K7_BOVIN", "mass": 64216.0, "length": 579, "protein_name": "Mitogen-activated protein kinase kinase kinase 7", "gene_name": "MAP3K7", "organism": "Bovine", "refseq_name": "mitogen-activated protein kinase kinase kinase 7", "refseq_ac": "NP_001075064", "gene_names_uniprotkb": "MAP3K7", "gene_names_refseq": "MAP3K7", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase 7; 2.7.11.25", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 7", "tax_id": 9913, "disease": "", "pathway": " (bta:529146); (R-BTA-168638); (R-BTA-202424); (R-BTA-2871837); (R-BTA-4086398); (R-BTA-445989); (R-BTA-450302); (R-BTA-450321); (R-BTA-5357956); (R-BTA-5607764); (R-BTA-5689880); (R-BTA-9020702); (R-BTA-937042); (R-BTA-937072); (R-BTA-9645460); (R-BTA-975163)", "pathway_count": 16, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs and c-jun N-terminal kinases (JNKs); both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1). Independently of MAP2Ks and p38 MAPKs, acts as a key activator of NF-kappa-B by promoting activation of the I-kappa-B-kinase (IKK) core complex. Mechanistically, recruited to polyubiquitin chains of RIPK2 and IKBKG/NEMO via TAB2/MAP3K7IP2 and TAB3/MAP3K7IP3, and catalyzes phosphorylation and activation of IKBKB/IKKB component of the IKK complex, leading to NF-kappa-B activation. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK1, but not that of NF-kappa-B. Promotes TRIM5 capsid-specific restriction activity. Phosphorylates RIPK1 at 'Ser-321' which positively regulates RIPK1 interaction with RIPK3 to promote necroptosis but negatively regulates RIPK1 kinase activity and its interaction with FADD to mediate apoptosis. Phosphorylates STING1 in response to cGAMP-activation, promoting association between STEEP1 and STING1 and STING1 translocation to COPII vesicles., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.3.2.27;2.7.1.153;2.7.1.137;2.7.1.154;3.4.19.12;2.3.2.31;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.3.2.23;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005102 signaling receptor binding;GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0004709 MAP kinase kinase kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005829 cytosol;GO:0140672 ATAC complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006955 immune response;GO:0006915 apoptotic process;GO:0007254 JNK cascade;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A2VDU3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5D7B7-1", "uniprot_id": "SEPR_BOVIN", "mass": 87734.0, "length": 760, "protein_name": "Prolyl endopeptidase FAP", "gene_name": "FAP", "organism": "Bovine", "refseq_name": "prolyl endopeptidase FAP", "refseq_ac": "NP_001091470", "gene_names_uniprotkb": "FAP", "gene_names_refseq": "FAP; SIMP; ZIP", "protein_names_uniprotkb": "Prolyl endopeptidase FAP; 3.4.14.5; 3.4.21.-; 3.4.21.26; Dipeptidyl peptidase FAP; FAPalpha; Fibroblast activation protein alpha; Gelatine degradation protease FAP; Integral membrane serine protease; Post-proline cleaving enzyme; SIMP; Seprase; Serine integral membrane protease; Surface-expressed protease; Z-Pro-prolinal insensitive peptidase; ZIP", "protein_names_refseq": "FAPalpha; Z-Pro-prolinal insensitive peptidase; dipeptidyl peptidase FAP; fibroblast activation protein, alpha subunit; gelatine degradation protease FAP; integral membrane serine protease; post-proline cleaving enzyme; prolyl endopeptidase FAP; seprase; serine integral membrane protease; surface-expressed protease", "tax_id": 9913, "disease": "", "pathway": " (bta:508882)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15313476;16507127;19393038", "class_list": "", "function": "Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation and tumor growth. Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences, on substrate such as alpha-2-antiplasmin SERPINF2 and SPRY2. Degrade also gelatin, heat-denatured type I collagen, but not native collagen type I and IV, vibronectin, tenascin, laminin, fibronectin, fibrin or casein. Also has dipeptidyl peptidase activity, exhibiting the ability to hydrolyze the prolyl bond two residues from the N-terminus of synthetic dipeptide substrates provided that the penultimate residue is proline, with a preference for Ala-Pro, Ile-Pro, Gly-Pro, Arg-Pro and Pro-Pro. Natural neuropeptide hormones for dipeptidyl peptidase are the neuropeptide Y (NPY), peptide YY (PYY), substance P (TAC1) and brain natriuretic peptide 32 (NPPB). The plasma membrane form, in association with either DPP4, PLAUR or integrins, is involved in the pericellular proteolysis of the extracellular matrix (ECM), and hence promotes cell adhesion, migration and invasion through the ECM. Plays a role in tissue remodeling during development and wound healing. Participates in the cell invasiveness towards the ECM in malignant melanoma cancers. Enhances tumor growth progression by increasing angiogenesis, collagen fiber degradation and apoptosis and by reducing antitumor response of the immune system. Promotes glioma cell invasion through the brain parenchyma by degrading the proteoglycan brevican. Acts as a tumor suppressor in melanocytic cells through regulation of cell proliferation and survival in a serine protease activity-independent manner., [UniProtKB, PubMed, UniProtKB]; Soluble form of a seprase activity is detected in bovine serum, [RefSeq, PubMed]; We clearly show an association between FAPalpha and chondrocytes in the context of cartilage degradation. (Fibroblast activation protein alpha), [RefSeq, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008239 dipeptidyl-peptidase activity;GO:0002020 protease binding;GO:0004252 serine-type endopeptidase activity;GO:0005178 integrin binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0045177 apical part of cell;GO:0045178 basal part of cell", "go_biological_process": "GO:0060244 negative regulation of cell proliferation involved in contact inhibition;GO:0097325 melanocyte proliferation;GO:1902362 melanocyte apoptotic process;GO:0001525 angiogenesis;GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A5D7B7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BN63-1", "uniprot_id": "E1BN63_BOVIN", "mass": 247692.0, "length": 2379, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "WNK1", "organism": "Bovine", "refseq_name": "serine/threonine-protein kinase WNK1 isoform X36", "refseq_ac": "XP_010803982", "gene_names_uniprotkb": "WNK1", "gene_names_refseq": "WNK1", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase WNK1 isoform X36", "tax_id": 9913, "disease": "", "pathway": " (bta:506433)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0030295 protein kinase activator activity;GO:0019902 phosphatase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005634 nucleus;GO:0005829 cytosol;GO:0032991 protein-containing complex;GO:0072686 mitotic spindle", "go_biological_process": "GO:0030644 intracellular chloride ion homeostasis;GO:0033633 negative regulation of cell-cell adhesion mediated by integrin;GO:0007507 heart development;GO:0010820 positive regulation of T cell chemotaxis;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BN63-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O46680-1", "uniprot_id": "TGFR1_BOVIN", "mass": 55814.0, "length": 499, "protein_name": "TGF-beta receptor type-1", "gene_name": "TGFBR1", "organism": "Bovine", "refseq_name": "TGF-beta receptor type-1 precursor", "refseq_ac": "NP_777046", "gene_names_uniprotkb": "TGFBR1", "gene_names_refseq": "TGFBR1", "protein_names_uniprotkb": "TGF-beta receptor type-1; 2.7.11.30; TGF-beta receptor type I; TGF-beta type I receptor; TGFR-1; TbetaR-I; Transforming growth factor-beta receptor type I", "protein_names_refseq": "TGF-beta receptor type I; TGF-beta receptor type-1 precursor; TGF-beta receptor type-1; TGF-beta type I receptor; TGFR-1; tbetaR-I; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa); transforming growth factor-beta receptor type I", "tax_id": 9913, "disease": "", "pathway": " (bta:282382); (R-BTA-2173788); (R-BTA-2173789); (R-BTA-2173791); (R-BTA-5689880); (R-BTA-9839389)", "pathway_count": 6, "publication_count": 10, "publication_id_list": "12471017;16004987;17972267;18456797;19506300;19710365;21465483;25266657;26382756;9406190", "class_list": "", "function": "ALK1 and ALK5 are both essential for correct regulation of VEGF, and that disruption of either pathway leads to disease., [RefSeq, PubMed]; ALK5 and Smad4 have roles in TGF-beta1-induced pulmonary endothelial permeability, [RefSeq, PubMed]; Found in binucleate cells of placenta, [RefSeq, PubMed]; GM-CSF induced airway smooth muscle cells to increase expression of transforming growth factor (TGF)-beta receptors type I, II, and III, but had no detectable effect on the release of TGF-beta1 by the same ASMC; corticosteroids were inhibitory, [RefSeq, PubMed]; Results show that ALK5 and ALK1 play antagonistic roles in TGF-beta-induced podosome formation in aortic endothelial cells., [RefSeq, PubMed]; TGF-beta1 downregulates caveolin-1 of cultured endothelial cells, involving ALK-5 receptor subtype, [RefSeq, PubMed]; These results indicate that high plasma cholesterol levels may contribute to the pathogenesis of certain diseases (e.g., atherosclerosis) by suppressing TGF-beta responsiveness., [RefSeq, PubMed]; This study showed that ubiquitinated ALK5 and phosphorylated heat shock protein 27 specifically accumulate in the cytoskeleton fraction, and ALK1 and ALK5 interact with heat shock protein 90., [RefSeq, PubMed]; Transforming growth factor-beta1 protects against pulmonary artery endothelial cell apoptosis via ALK5., [RefSeq, PubMed]; Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFBR1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways. For instance, TGFBR1 induces TRAF6 autoubiquitination which in turn results in MAP3K7 ubiquitination and activation to trigger apoptosis. Also regulates epithelial to mesenchymal transition through a SMAD-independent signaling pathway through PARD6A phosphorylation and activation (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.30;2.3.2.26;5.2.1.8;3.6.5.2;3.4.19.12", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0005025 transforming growth factor beta receptor activity, type I;GO:0016361 activin receptor activity, type I;GO:0046332 SMAD binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005768 endosome;GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0009986 cell surface", "go_biological_process": "GO:0010717 regulation of epithelial to mesenchymal transition;GO:0007399 nervous system development;GO:0007507 heart development;GO:0010628 positive regulation of gene expression;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "O46680-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5PJZ1-1", "uniprot_id": "SCMC1_BOVIN", "mass": 53285.0, "length": 477, "protein_name": "Mitochondrial adenyl nucleotide antiporter SLC25A24", "gene_name": "SLC25A24", "organism": "Bovine", "refseq_name": "mitochondrial adenyl nucleotide antiporter SLC25A24", "refseq_ac": "NP_001092536", "gene_names_uniprotkb": "SLC25A24", "gene_names_refseq": "SCaMC-1; SLC25A24", "protein_names_uniprotkb": "Mitochondrial adenyl nucleotide antiporter SLC25A24; SCaMC-1; Small calcium-binding mitochondrial carrier protein 1; Solute carrier family 25 member 24", "protein_names_refseq": "calcium-binding mitochondrial carrier protein SCaMC-1-like; calcium-binding mitochondrial carrier protein SCaMC-1; mitochondrial adenyl nucleotide antiporter SLC25A24; phosphate carrier), member 24; small calcium-binding mitochondrial carrier protein 1; solute carrier family 25 (mitochondrial carrier", "tax_id": 9913, "disease": "", "pathway": " (bta:534742)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenyl nucleotide pool, could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides. May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0000295 adenine nucleotide transmembrane transporter activity;GO:0005347 ATP transmembrane transporter activity;GO:0140987 ATP:phosphate antiporter activity;GO:0140988 ADP:phosphate antiporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006839 mitochondrial transport;GO:0071277 cellular response to calcium ion;GO:0034599 cellular response to oxidative stress;GO:0015866 ADP transport;GO:0015867 ATP transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A5PJZ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A4FUF0-1", "uniprot_id": "GLYR1_BOVIN", "mass": 60556.0, "length": 553, "protein_name": "Cytokine-like nuclear factor N-PAC", "gene_name": "GLYR1", "organism": "Bovine", "refseq_name": "cytokine-like nuclear factor N-PAC", "refseq_ac": "NP_001035658", "gene_names_uniprotkb": "GLYR1; NP60", "gene_names_refseq": "GLYR1; N-PAC; NPAC", "protein_names_uniprotkb": "Cytokine-like nuclear factor N-PAC; Glyoxylate reductase 1 homolog; NPAC; Nuclear protein NP60; Putative oxidoreductase GLYR1", "protein_names_refseq": "cytokine-like nuclear factor N-PAC; nuclear protein NP60; putative oxidoreductase GLYR1", "tax_id": 9913, "disease": "", "pathway": " (bta:539636)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Cytokine-like nuclear factor with chromatin gene reader activity involved in chromatin modification and regulation of gene expression. Acts as a nucleosome-destabilizing factor that is recruited to genes during transcriptional activation. Recognizes and binds histone H3 without a preference for specific epigenetic markers and also binds DNA. Interacts with KDM1B and promotes its histone demethylase activity by facilitating the capture of H3 tails, they form a multifunctional enzyme complex that modifies transcribed chromatin and facilitates Pol II transcription through nucleosomes. Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by EP300. With GATA4, co-binds a defined set of heart development genes and coregulates their expression during cardiomyocyte differentiation. Regulates p38 MAP kinase activity by mediating stress activation of MAPK14/p38alpha and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q58DC3", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0051287 NAD binding;GO:0042393 histone binding;GO:0031491 nucleosome binding;GO:0050661 NADP binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:0000786 nucleosome;GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0045815 transcription initiation-coupled chromatin remodeling;GO:0140673 transcription elongation-coupled chromatin remodeling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A4FUF0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G3X6U1-1", "uniprot_id": "G3X6U1_BOVIN", "mass": 56691.0, "length": 518, "protein_name": "Aldehyde dehydrogenase 1 family member A2", "gene_name": "ALDH1A2", "organism": "Bovine", "refseq_name": "retinal dehydrogenase 2", "refseq_ac": "XP_002690901", "gene_names_uniprotkb": "ALDH1A2", "gene_names_refseq": "ALDH1A2", "protein_names_uniprotkb": "Aldehyde dehydrogenase 1 family member A2", "protein_names_refseq": "retinal dehydrogenase 2", "tax_id": 9913, "disease": "", "pathway": " (bta:535075); (R-BTA-5365859)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004029 aldehyde dehydrogenase (NAD+) activity;GO:0001758 retinal dehydrogenase (NAD+) activity;GO:0004028 3-chloroallyl aldehyde dehydrogenase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0051289 protein homotetramerization;GO:0071300 cellular response to retinoic acid;GO:0006081 aldehyde metabolic process;GO:0002138 retinoic acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3X6U1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BQ12-1", "uniprot_id": "E1BQ12_BOVIN", "mass": 140031.0, "length": 1253, "protein_name": "Adenylate cyclase type 8", "gene_name": "ADCY8", "organism": "Bovine", "refseq_name": "adenylate cyclase type 8", "refseq_ac": "NP_001179770", "gene_names_uniprotkb": "ADCY8", "gene_names_refseq": "ADCY8", "protein_names_uniprotkb": "Adenylate cyclase type 8; 4.6.1.1", "protein_names_refseq": "adenylate cyclase type 8", "tax_id": 9913, "disease": "", "pathway": " (bta:535017); (R-BTA-163615); (R-BTA-170660); (R-BTA-170670); (R-BTA-418597); (R-BTA-5610787)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "24071896;38351373", "class_list": "", "function": "CaM is collapsed around the adenylyl cyclase 8 peptides that binds to CaM in an antiparallel orientation., [RefSeq, PubMed]; Catalyzes the formation of cAMP in response to calcium entry leadings to cAMP signaling activation that affect processes suche as synaptic plasticity and insulin secretion. Plays a role in many brain functions, such as learning, memory, drug addiction, and anxiety modulation through regulation of synaptic plasticity by modulating long-term memory and long-term potentiation (LTP) through CREB transcription factor activity modulation. Plays a central role in insulin secretion by controlling glucose homeostasis through glucagon-like peptide 1 and glucose signaling pathway and maintains insulin secretion through calcium-dependent PKA activation leading to vesicle pool replenishment. Also, allows PTGER3 to induce potentiation of PTGER4-mediated PLA2 secretion by switching from a negative to a positive regulation, during the IL1B induced-dedifferentiation of smooth muscle cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.6.1.1;3.6.5.-;2.7.7.85", "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity", "go_cellular_component": "GO:0005905 clathrin-coated pit;GO:0014069 postsynaptic density;GO:0016323 basolateral plasma membrane;GO:0030425 dendrite;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0035556 intracellular signal transduction;GO:0050796 regulation of insulin secretion;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007613 memory", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "E1BQ12-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A4IFJ5-1", "uniprot_id": "PA24A_BOVIN", "mass": 85350.0, "length": 749, "protein_name": "Cytosolic phospholipase A2", "gene_name": "PLA2G4A", "organism": "Bovine", "refseq_name": "cytosolic phospholipase A2", "refseq_ac": "NP_001069332", "gene_names_uniprotkb": "PLA2G4A; CPLA2; PLA2G4", "gene_names_refseq": "PLA2G4A", "protein_names_uniprotkb": "Cytosolic phospholipase A2; Phosphatidylcholine 2-acylhydrolase; Phospholipase A2 group IVA; cPLA2", "protein_names_refseq": "cPLA2; cytosolic phospholipase A2; phospholipase A2, group IVA (cytosolic, calcium-dependent)", "tax_id": 9913, "disease": "", "pathway": " (bta:525072); (R-BTA-111995); (R-BTA-1482788); (R-BTA-1482798); (R-BTA-1482801); (R-BTA-1482839); (R-BTA-1482922); (R-BTA-1482925); (R-BTA-1483115); (R-BTA-1483166); (R-BTA-2142753); (R-BTA-418592); (R-BTA-432142); (R-BTA-6811436)", "pathway_count": 14, "publication_count": 3, "publication_id_list": "16510840;18385289;21613292", "class_list": "", "function": "Activation of cytosolic phospholipase A2 and fatty acid transacylase is essential but not sufficient for thrombin-induced smooth muscle cell proliferation., [RefSeq, PubMed]; Has primarily calcium-dependent phospholipase and lysophospholipase activities, with a major role in membrane lipid remodeling and biosynthesis of lipid mediators of the inflammatory response (By similarity). Plays an important role in embryo implantation and parturition through its ability to trigger prostanoid production (By similarity). Preferentially hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity). Selectively hydrolyzes sn-2 arachidonoyl group from membrane phospholipids, providing the precursor for eicosanoid biosynthesis via the cyclooxygenase pathway. In an alternative pathway of eicosanoid biosynthesis, hydrolyzes sn-2 fatty acyl chain of eicosanoid lysophopholipids to release free bioactive eicosanoids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-1 position of phospholipids (phospholipase A1 activity) only if an ether linkage rather than an ester linkage is present at the sn-2 position. This hydrolysis is not stereospecific. Has calcium-independent phospholipase A2 and lysophospholipase activities in the presence of phosphoinositides. Has O-acyltransferase activity. Catalyzes the transfer of fatty acyl chains from phospholipids to a primary hydroxyl group of glycerol (sn-1 or sn-3), potentially contributing to monoacylglycerol synthesis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Ovulation is associated with an LH/hCG-dependent induction of PLA2G4A in GC via the adenylyl cyclase/cAMP pathway., [RefSeq, PubMed]; Result suggests that cPLAPgamma may act as a G protein, activating cPLA(2)alpha prior to reaching full intracellular Ca(2 ) concentrations, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1XD55", "ec_number_list": "3.1.1.4;3.1.1.3;3.1.1.5;3.1.2.22;1.11.1.27;3.1.2.2;3.5.1.1;3.1.1.47;2.3.1.23;3.1.1.13;3.1.1.6;2.3.1.149;3.1.1.32;3.1.2.-;2.3.1.-", "go_molecular_function": "GO:0010314 phosphatidylinositol-5-phosphate binding;GO:0005509 calcium ion binding;GO:0004622 phosphatidylcholine lysophospholipase activity;GO:0004623 phospholipase A2 activity;GO:0005544 calcium-dependent phospholipid binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0034638 phosphatidylcholine catabolic process;GO:0046475 glycerophospholipid catabolic process;GO:0019370 leukotriene biosynthetic process;GO:0006071 glycerol metabolic process;GO:0019369 arachidonate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A4IFJ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6QLT2-1", "uniprot_id": "MTMR2_BOVIN", "mass": 73348.0, "length": 643, "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2", "gene_name": "MTMR2", "organism": "Bovine", "refseq_name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2", "refseq_ac": "NP_001095664", "gene_names_uniprotkb": "MTMR2", "gene_names_refseq": "MTMR2", "protein_names_uniprotkb": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2; 3.1.3.95; Myotubularin-related protein 2; Phosphatidylinositol-3-phosphate phosphatase", "protein_names_refseq": "Myotubularin-related protein 2; phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2; phosphatidylinositol-3,5-bisphosphate 3-phosphatase; phosphatidylinositol-3-phosphate phosphatase", "tax_id": 9913, "disease": "", "pathway": " (bta:536810); (R-BTA-1483248); (R-BTA-1660516); (R-BTA-1660517)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate, generating phosphatidylinositol and phosphatidylinositol 5-phosphate. Regulates the level of these phosphoinositides critical for various biological processes including autophagy initiation and autophagosome maturation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.64;3.1.3.95;3.1.3.67;3.1.3.86;3.1.3.-;3.1.3.36", "go_molecular_function": "GO:0042802 identical protein binding;GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity;GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016020 membrane;GO:0030424 axon", "go_biological_process": "GO:0060304 regulation of phosphatidylinositol dephosphorylation;GO:0046856 phosphatidylinositol dephosphorylation;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6QLT2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5PJM4-1", "uniprot_id": "FSP1_BOVIN", "mass": 40477.0, "length": 373, "protein_name": "Ferroptosis suppressor protein 1", "gene_name": "AIFM2", "organism": "Bovine", "refseq_name": "ferroptosis suppressor protein 1", "refseq_ac": "NP_001300960", "gene_names_uniprotkb": "AIFM2", "gene_names_refseq": "AIFM2; AMID; FSP1", "protein_names_uniprotkb": "Ferroptosis suppressor protein 1; 1.6.5.-; AMID; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; FSP1; p53-responsive gene 3 protein", "protein_names_refseq": "apoptosis-inducing factor (AIF)-like mitchondrion-associated inducer of death; apoptosis-inducing factor 2; apoptosis-inducing factor homologous mitochondrion-associated inducer of death; apoptosis-inducing factor, mitochondrion-associated, 2; ferroptosis suppressor protein 1; p53-responsive gene 3 protein", "tax_id": 9913, "disease": "", "pathway": " (bta:534217)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "A NAD(P)H-dependent oxidoreductase that acts as a key inhibitor of ferroptosis. At the plasma membrane, catalyzes reduction of coenzyme Q/ubiquinone-10 to ubiquinol-10, a lipophilic radical-trapping antioxidant that prevents lipid oxidative damage and consequently ferroptosis. Acts in parallel to GPX4 to suppress phospholipid peroxidation and ferroptosis. This anti-ferroptotic function is independent of cellular glutathione levels. Also acts as a potent radical-trapping antioxidant by mediating warfarin-resistant vitamin K reduction in the canonical vitamin K cycle: catalyzes NAD(P)H-dependent reduction of vitamin K (phylloquinone, menaquinone-4 and menadione) to hydroquinone forms. Hydroquinones act as potent radical-trapping antioxidants inhibitor of phospholipid peroxidation and ferroptosis. May play a role in mitochondrial stress signaling. Upon oxidative stress, associates with the lipid peroxidation end product 4-hydroxy-2-nonenal (HNE) forming a lipid adduct devoid of oxidoreductase activity, which then translocates from mitochondria into the nucleus triggering DNA damage and cell death., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.6.5.-", "go_molecular_function": "GO:0003677 DNA binding;GO:0050660 flavin adenine dinucleotide binding;GO:0004174 electron-transferring-flavoprotein dehydrogenase activity;GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005741 mitochondrial outer membrane;GO:0005811 lipid droplet;GO:0005829 cytosol", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0008637 apoptotic mitochondrial changes;GO:1900407 regulation of cellular response to oxidative stress;GO:0042373 vitamin K metabolic process;GO:0006743 ubiquinone metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A5PJM4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MZD6-1", "uniprot_id": "F1MZD6_BOVIN", "mass": 83331.0, "length": 730, "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "organism": "Bovine", "refseq_name": "hepatocyte growth factor isoform X1", "refseq_ac": "XP_005205371", "gene_names_uniprotkb": "HGF", "gene_names_refseq": "HGF", "protein_names_uniprotkb": "Hepatocyte growth factor; Hepatopoietin-A; Scatter factor", "protein_names_refseq": "hepatocyte growth factor isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-114608); (R-BTA-1257604); (R-BTA-5673001); (R-BTA-6806942); (R-BTA-6807004); (R-BTA-6811558); (R-BTA-8851805); (R-BTA-8851907); (R-BTA-8865999); (R-BTA-8874081); (R-BTA-8875513); (R-BTA-8875555); (R-BTA-8875656); (R-BTA-8875791); (R-BTA-9734091)", "pathway_count": 15, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Activates MAPK signaling following TMPRSS13 cleavage and activation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0008083 growth factor activity;GO:0005102 signaling receptor binding;GO:0042056 chemoattractant activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0043066 negative regulation of apoptotic process;GO:0048513 animal organ development;GO:0051239 regulation of multicellular organismal process;GO:0022603 regulation of anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MZD6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A7MB74-1", "uniprot_id": "SGK1_BOVIN", "mass": 49026.0, "length": 431, "protein_name": "Serine/threonine-protein kinase Sgk1", "gene_name": "SGK1", "organism": "Bovine", "refseq_name": "serine/threonine-protein kinase Sgk1", "refseq_ac": "NP_001095503", "gene_names_uniprotkb": "SGK1; SGK", "gene_names_refseq": "SGK1", "protein_names_uniprotkb": "Serine/threonine-protein kinase Sgk1; 2.7.11.1; Serum/glucocorticoid-regulated kinase 1", "protein_names_refseq": "serine/threonine-protein kinase Sgk1", "tax_id": 9913, "disease": "", "pathway": " (bta:515854)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cellular enzymes, transcription factors, neuronal excitability, cell growth, proliferation, survival, migration and apoptosis. Plays an important role in cellular stress response. Contributes to regulation of renal Na(+) retention, renal K(+) elimination, salt appetite, gastric acid secretion, intestinal Na(+)/H(+) exchange and nutrient transport, insulin-dependent salt sensitivity of blood pressure, salt sensitivity of peripheral glucose uptake, cardiac repolarization and memory consolidation. Up-regulates Na(+) channels: SCNN1A/ENAC, SCN5A and ASIC1/ACCN2, K(+) channels: KCNJ1/ROMK1, KCNA1-5, KCNQ1-5 and KCNE1, epithelial Ca(2+) channels: TRPV5 and TRPV6, chloride channels: BSND, CLCN2 and CFTR, glutamate transporters: SLC1A3/EAAT1, SLC1A2 /EAAT2, SLC1A1/EAAT3, SLC1A6/EAAT4 and SLC1A7/EAAT5, amino acid transporters: SLC1A5/ASCT2, SLC38A1/SN1 and SLC6A19, creatine transporter: SLC6A8, Na(+)/dicarboxylate cotransporter: SLC13A2/NADC1, Na(+)-dependent phosphate cotransporter: SLC34A2/NAPI-2B, glutamate receptor: GRIK2/GLUR6. Up-regulates carriers: SLC9A3/NHE3, SLC12A1/NKCC2, SLC12A3/NCC, SLC5A3/SMIT, SLC2A1/GLUT1, SLC5A1/SGLT1 and SLC15A2/PEPT2. Regulates enzymes: GSK3A/B, PMM2 and Na(+)/K(+) ATPase, and transcription factors: CTNNB1 and nuclear factor NF-kappa-B. Stimulates sodium transport into epithelial cells by enhancing the stability and expression of SCNN1A/ENAC. This is achieved by phosphorylating the NEDD4L ubiquitin E3 ligase, promoting its interaction with 14-3-3 proteins, thereby preventing it from binding to SCNN1A/ENAC and targeting it for degradation. Regulates store-operated Ca(+2) entry (SOCE) by stimulating ORAI1 and STIM1. Regulates KCNJ1/ROMK1 directly via its phosphorylation or indirectly via increased interaction with SLC9A3R2/NHERF2. Phosphorylates MDM2 and activates MDM2-dependent ubiquitination of p53/TP53. Phosphorylates MAPT/TAU and mediates microtubule depolymerization and neurite formation in hippocampal neurons. Phosphorylates SLC2A4/GLUT4 and up-regulates its activity. Phosphorylates APBB1/FE65 and promotes its localization to the nucleus. Phosphorylates MAPK1/ERK2 and activates it by enhancing its interaction with MAP2K1/MEK1 and MAP2K2/MEK2. Phosphorylates FBXW7 and plays an inhibitory role in the NOTCH1 signaling. Phosphorylates FOXO1 resulting in its relocalization from the nucleus to the cytoplasm. Phosphorylates FOXO3, promoting its exit from the nucleus and interference with FOXO3-dependent transcription. Phosphorylates BRAF and MAP3K3/MEKK3 and inhibits their activity. Phosphorylates SLC9A3/NHE3 in response to dexamethasone, resulting in its activation and increased localization at the cell membrane. Phosphorylates CREB1. Necessary for vascular remodeling during angiogenesis (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A7MB74-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSD2-1", "uniprot_id": "F1MSD2_BOVIN", "mass": 54596.0, "length": 493, "protein_name": "RuvB-like helicase", "gene_name": "RUVBL2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RUVBL2", "gene_names_refseq": "", "protein_names_uniprotkb": "RuvB-like helicase; 3.6.4.12", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003678 DNA helicase activity;GO:0042803 protein homodimerization activity;GO:0051117 ATPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0120293 dynein axonemal particle;GO:0097255 R2TP complex;GO:0005829 cytosol;GO:0031011 Ino80 complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006351 DNA-templated transcription;GO:0060382 regulation of DNA strand elongation;GO:0006338 chromatin remodeling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSD2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5D7L5-1", "uniprot_id": "S39AE_BOVIN", "mass": 53934.0, "length": 490, "protein_name": "Metal cation symporter ZIP14", "gene_name": "SLC39A14", "organism": "Bovine", "refseq_name": "metal cation symporter ZIP14 precursor", "refseq_ac": "NP_001091505", "gene_names_uniprotkb": "SLC39A14", "gene_names_refseq": "SLC39A14", "protein_names_uniprotkb": "Metal cation symporter ZIP14; Solute carrier family 39 member 14; ZIP-14; Zrt- and Irt-like protein 14", "protein_names_refseq": "ZIP-14; metal cation symporter ZIP14 precursor; metal cation symporter ZIP14; solute carrier family 39 (zinc transporter), member 14; zinc transporter ZIP14; zrt- and Irt-like protein 14", "tax_id": 9913, "disease": "", "pathway": " (bta:515437); (R-BTA-442380)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Electroneutral transporter of the plasma membrane mediating the cellular uptake of the divalent metal cations zinc, manganese and iron that are important for tissue homeostasis, metabolism, development and immunity (By similarity). Functions as an energy-dependent symporter, transporting through the membranes an electroneutral complex composed of a divalent metal cation and two bicarbonate anions. Beside these endogenous cellular substrates, can also import cadmium a non-essential metal which is cytotoxic and carcinogenic (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0005384 manganese ion transmembrane transporter activity;GO:0015086 cadmium ion transmembrane transporter activity;GO:0005381 iron ion transmembrane transporter activity;GO:0015296 monoatomic anion:monoatomic cation symporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0005765 lysosomal membrane;GO:0016324 apical plasma membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0071577 zinc ion transmembrane transport;GO:0034755 iron ion transmembrane transport;GO:0032869 cellular response to insulin stimulus;GO:0045745 positive regulation of G protein-coupled receptor signaling pathway;GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A5D7L5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUT3-1", "uniprot_id": "F1MUT3_BOVIN", "mass": 146920.0, "length": 1333, "protein_name": "Xanthine dehydrogenase/oxidase", "gene_name": "XDH", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "XDH", "gene_names_refseq": "", "protein_names_uniprotkb": "Xanthine dehydrogenase/oxidase; 1.17.1.4; 1.17.3.2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-74259); (R-BTA-8851680); (R-BTA-9748787)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1MKA4", "ec_number_list": "1.17.1.4;1.17.3.2", "go_molecular_function": "GO:0005506 iron ion binding;GO:0071949 FAD binding;GO:0051537 2 iron, 2 sulfur cluster binding;GO:0043546 molybdopterin cofactor binding;GO:0004854 xanthine dehydrogenase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005777 peroxisome;GO:0005576 extracellular region", "go_biological_process": "GO:0009115 xanthine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MUT3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6QLJ0-1", "uniprot_id": "ERCC2_BOVIN", "mass": 86999.0, "length": 760, "protein_name": "General transcription and DNA repair factor IIH helicase subunit XPD", "gene_name": "ERCC2", "organism": "Bovine", "refseq_name": "general transcription and DNA repair factor IIH helicase subunit XPD", "refseq_ac": "NP_001096787", "gene_names_uniprotkb": "ERCC2", "gene_names_refseq": "ERCC2", "protein_names_uniprotkb": "General transcription and DNA repair factor IIH helicase subunit XPD; 5.6.2.3; CXPD; DNA 5'-3' helicase XPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; TFIIH subunit XPD; Xeroderma pigmentosum group D-complementing protein", "protein_names_refseq": "CXPD; DNA 5'-3' helicase XPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; TFIIH basal transcription factor complex helicase XPD subunit; TFIIH basal transcription factor complex helicase subunit; TFIIH subunit XPD; excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D); excision repair cross-complementing rodent repair deficiency, complementation group 6-like group 2; general transcription and DNA repair factor IIH helicase subunit XPD; xeroderma pigmentosum group D-complementing protein", "tax_id": 9913, "disease": "", "pathway": " (bta:100125238); (R-BTA-113418); (R-BTA-5696395); (R-BTA-5696400); (R-BTA-674695); (R-BTA-6781823); (R-BTA-6782135); (R-BTA-6782210); (R-BTA-6796648); (R-BTA-72086); (R-BTA-73762); (R-BTA-73772); (R-BTA-73776); (R-BTA-73779); (R-BTA-73863); (R-BTA-75953); (R-BTA-75955); (R-BTA-76042); (R-BTA-77075)", "pathway_count": 19, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "ATP-dependent 5'-3' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CDK-activating kinase (CAK), involved in transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATP-dependent helicase activity of XPD/ERCC2 is required for DNA opening. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription. XPD/ERCC2 acts by forming a bridge between CAK and the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;6.5.1.1;5.2.1.8;3.6.4.10;3.4.19.12;2.4.2.-;2.4.2.30;5.6.2.3;3.6.5.-;1.14.11.-;5.6.2.-;2.7.4.3;3.6.4.-;3.1.13.-;2.7.7.48;2.7.7.6;2.7.11.1;3.1.-.-;2.1.1.56;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;2.3.1.48;2.7.11.22;2.7.11.23;3.1.3.1;3.9.1.1;2.3.2.23;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0003684 damaged DNA binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0071817 MMXD complex;GO:0005675 transcription factor TFIIH holo complex", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0007059 chromosome segregation;GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:1901990 regulation of mitotic cell cycle phase transition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6QLJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1A4K5-1", "uniprot_id": "ENPP2_BOVIN", "mass": 101717.0, "length": 888, "protein_name": "Autotaxin", "gene_name": "ENPP2", "organism": "Bovine", "refseq_name": "autotaxin precursor", "refseq_ac": "NP_001073762", "gene_names_uniprotkb": "ENPP2", "gene_names_refseq": "ENPP2", "protein_names_uniprotkb": "Autotaxin; 3.1.4.39; 3.1.4.4; E-NPP 2; Ectonucleotide pyrophosphatase/phosphodiesterase family member 2; Extracellular lysophospholipase D; LysoPLD", "protein_names_refseq": "E-NPP 2; autotaxin precursor; autotaxin; ectonucleotide pyrophosphatase/phosphodiesterase family member 2; extracellular lysophospholipase D; lysoPLD", "tax_id": 9913, "disease": "", "pathway": " (bta:532663)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12119361;16837466;23522079", "class_list": "", "function": "Expression is greater in epithelial cells than in stromal cells of the endometrium, [RefSeq, PubMed]; Secreted lysophospholipase D that hydrolyzes lysophospholipids to produce the signaling molecule lysophosphatidic acid (LPA) in extracellular fluids. Its major substrate is lysophosphatidylcholine (PubMed:12119361). Can also act on sphingosylphosphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development (By similarity). Required for LPA production in activated platelets, cleaves the sn-1 lysophospholipids to generate sn-1 lysophosphatidic acids containing predominantly 18:2 and 20:4 fatty acids (By similarity). Shows a preference for the sn-1 to the sn-2 isomer of 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) (By similarity)., [UniProtKB, PubMed, UniProtKB]; These results indicate that the generation of cyclic phosphatidic acid and lysophosphatidic acid in serum is mainly attributed to autotaxin., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.4.4;3.1.4.39", "go_molecular_function": "GO:0030247 polysaccharide binding;GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity;GO:0004630 phospholipase D activity;GO:0005044 scavenger receptor activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0005576 extracellular region", "go_biological_process": "GO:0034638 phosphatidylcholine catabolic process;GO:0030149 sphingolipid catabolic process;GO:0006935 chemotaxis;GO:0006955 immune response;GO:0009395 phospholipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A1A4K5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G3MZV8-1", "uniprot_id": "G3MZV8_BOVIN", "mass": 64010.0, "length": 567, "protein_name": "TGF-beta receptor type-2", "gene_name": "TGFBR2", "organism": "Bovine", "refseq_name": "TGF-beta receptor type-2 precursor", "refseq_ac": "NP_001153038", "gene_names_uniprotkb": "TGFBR2", "gene_names_refseq": "TGFBR2", "protein_names_uniprotkb": "TGF-beta receptor type-2; 2.7.11.30; TGF-beta type II receptor; TGFR-2; Transforming growth factor-beta receptor type II", "protein_names_refseq": "TGF-beta receptor type-2 precursor; transforming growth factor, beta receptor II (70/80kDa)", "tax_id": 9913, "disease": "", "pathway": " (bta:535376); (R-BTA-2173788); (R-BTA-2173789); (R-BTA-2173791); (R-BTA-9839389)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "17972267;26382756", "class_list": "", "function": "Found in binucleate cells of placenta, [RefSeq, PubMed]; These results indicate that high plasma cholesterol levels may contribute to the pathogenesis of certain diseases (e.g., atherosclerosis) by suppressing TGF-beta responsiveness., [RefSeq, PubMed]; Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.30;2.3.2.27;2.3.2.34;2.3.2.26;5.2.1.8;3.6.5.2", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0005026 transforming growth factor beta receptor activity, type II;GO:0019209 kinase activator activity;GO:0005024 transforming growth factor beta receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0043235 receptor complex;GO:0045121 membrane raft;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0006915 apoptotic process;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0033993 response to lipid;GO:0048514 blood vessel morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "G3MZV8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G3X757-1", "uniprot_id": "G3X757_BOVIN", "mass": 89303.0, "length": 806, "protein_name": "Transitional endoplasmic reticulum ATPase", "gene_name": "VCP", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "VCP", "gene_names_refseq": "", "protein_names_uniprotkb": "Transitional endoplasmic reticulum ATPase; 15S Mg(2+)-ATPase p97 subunit; 3.6.4.6; Valosin-containing protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-110320); (R-BTA-3371511); (R-BTA-382556); (R-BTA-532668); (R-BTA-5358346); (R-BTA-5689877); (R-BTA-5689896); (R-BTA-6798695); (R-BTA-8951664); (R-BTA-9013407); (R-BTA-9755511); (R-BTA-9931269)", "pathway_count": 12, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.42;3.6.4.12;2.5.1.18;5.6.2.4;3.6.4.13;2.7.1.1;2.7.11.24;5.3.4.1;2.3.2.27;7.2.2.-;2.7.11.1;2.7.7.7;2.7.7.49;3.6.1.5;2.1.1.13;3.6.4.6;2.7.11.39;3.2.1.23;2.4.2.1;5.2.1.8;3.6.4.10;4.1.2.13;3.6.1.6;3.1.3.16;5.6.2.3;3.1.6.4;3.6.5.-;3.1.6.14;1.1.1.205;2.7.1.11;5.6.2.-;3.4.24.-;2.7.4.3;3.6.4.-;3.4.19.9;3.2.1.-;3.1.-.-;2.7.11.22;2.7.11.23;3.5.1.52;2.7.10.2;2.3.2.26;3.5.1.26;2.4.1.25;3.2.1.33;4.2.99.18;3.4.23.5;5.6.1.6;1.13.11.34;1.13.11.12;3.6.1.15;2.4.1.1;1.6.5.5;7.6.2.1;3.5.4.4;3.2.1.51;3.2.1.52;1.16.3.1;1.11.1.27;3.1.1.4;2.3.1.23;1.11.1.6;3.4.18.1;1.6.2.2;3.4.22.1;3.1.3.1;3.9.1.1;2.3.1.168;2.3.1.-;3.4.22.27;3.4.24.35;3.1.1.47;5.3.2.1;5.3.3.12;3.2.1.17;3.4.19.1;3.4.19.12;3.1.6.8;2.7.1.35;5.6.2.5;2.7.10.4;3.5.1.23;3.5.1.-;3.4.22.52;3.2.1.24;1.14.11.-;3.5.3.1;3.6.-.-;3.6.1.-;5.6.1.7;2.3.3.8;3.4.16.5;3.4.16.-;5.4.2.11;5.4.2.4;3.3.2.6;3.4.11.4;3.4.21.46;2.7.4.6;2.7.13.3;4.1.2.4;5.3.1.9;5.1.3.-;5.3.99.3;3.1.4.-;2.4.2.7;4.2.1.24;3.4.21.53", "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0016887 ATP hydrolysis activity;GO:0008289 lipid binding;GO:0036435 K48-linked polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:1990730 VCP-NSFL1C complex;GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex;GO:0005634 nucleus;GO:0005829 cytosol;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0006914 autophagy;GO:0030970 retrograde protein transport, ER to cytosol;GO:0097352 autophagosome maturation;GO:2001171 positive regulation of ATP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3X757-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MHP0-1", "uniprot_id": "F1MHP0_BOVIN", "mass": 228011.0, "length": 2022, "protein_name": "Sodium channel protein", "gene_name": "SCN5A", "organism": "Bovine", "refseq_name": "sodium channel protein type 5 subunit alpha isoform X1", "refseq_ac": "XP_024838160", "gene_names_uniprotkb": "SCN5A", "gene_names_refseq": "SCN5A", "protein_names_uniprotkb": "Sodium channel protein", "protein_names_refseq": "sodium channel protein type 5 subunit alpha isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5576892)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.-.-", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential;GO:0086060 voltage-gated sodium channel activity involved in AV node cell action potential;GO:0086061 voltage-gated sodium channel activity involved in bundle of His cell action potential;GO:0086063 voltage-gated sodium channel activity involved in SA node cell action potential", "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm;GO:0014704 intercalated disc;GO:0030315 T-tubule;GO:0001518 voltage-gated sodium channel complex;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0048731 system development;GO:0002027 regulation of heart rate;GO:0048513 animal organ development;GO:0090257 regulation of muscle system process;GO:0098719 sodium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MHP0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1B8E7-1", "uniprot_id": "E1B8E7_BOVIN", "mass": 344329.0, "length": 3129, "protein_name": "Huntingtin", "gene_name": "HTT", "organism": "Bovine", "refseq_name": "huntingtin isoform X1", "refseq_ac": "XP_002688476", "gene_names_uniprotkb": "HTT", "gene_names_refseq": "HTT", "protein_names_uniprotkb": "Huntingtin", "protein_names_refseq": "huntingtin isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:615059)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in microtubule-mediated transport or vesicle function., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Promotes the formation of autophagic vesicles., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0031072 heat shock protein binding;GO:0044325 transmembrane transporter binding;GO:0019900 kinase binding;GO:0048487 beta-tubulin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0030424 axon;GO:0045202 synapse;GO:0031410 cytoplasmic vesicle;GO:0005776 autophagosome", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0009966 regulation of signal transduction;GO:0007017 microtubule-based process;GO:1901526 positive regulation of mitophagy;GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1B8E7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N5V3-1", "uniprot_id": "F1N5V3_BOVIN", "mass": 55173.0, "length": 492, "protein_name": "Tyrosine 3-monooxygenase", "gene_name": "TH", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TH", "gene_names_refseq": "", "protein_names_uniprotkb": "Tyrosine 3-monooxygenase; 1.14.16.2; Tyrosine 3-hydroxylase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-209905)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.16.2", "go_molecular_function": "GO:0005506 iron ion binding;GO:0004511 tyrosine 3-monooxygenase activity;GO:0019899 enzyme binding", "go_cellular_component": "GO:0030424 axon;GO:0048471 perinuclear region of cytoplasm;GO:0008021 synaptic vesicle;GO:0005737 cytoplasm;GO:0043204 perikaryon", "go_biological_process": "GO:0042416 dopamine biosynthetic process;GO:0009072 aromatic amino acid metabolic process;GO:0006585 dopamine biosynthetic process from tyrosine;GO:0007617 mating behavior;GO:0050890 cognition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N5V3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MTT1-1", "uniprot_id": "F1MTT1_BOVIN", "mass": 55868.0, "length": 486, "protein_name": "Bile acid receptor", "gene_name": "NR1H4", "organism": "Bovine", "refseq_name": "bile acid receptor isoform X1", "refseq_ac": "XP_005206718", "gene_names_uniprotkb": "NR1H4", "gene_names_refseq": "NR1H4", "protein_names_uniprotkb": "Bile acid receptor; Farnesoid X-activated receptor; Farnesol receptor HRR-1; Nuclear receptor subfamily 1 group H member 4", "protein_names_refseq": "bile acid receptor isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-159418); (R-BTA-192105); (R-BTA-193368); (R-BTA-193807); (R-BTA-211976); (R-BTA-383280); (R-BTA-4090294)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0032052 bile acid binding;GO:0038186 bile acid nuclear receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0043235 receptor complex;GO:0000791 euchromatin;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0038185 nuclear receptor-mediated bile acid signaling pathway;GO:0006351 DNA-templated transcription;GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0070328 triglyceride homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MTT1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N3Q7-1", "uniprot_id": "F1N3Q7_BOVIN", "mass": 51278.0, "length": 455, "protein_name": "Apolipoprotein A-IV", "gene_name": "APOA4", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "APOA4", "gene_names_refseq": "", "protein_names_uniprotkb": "Apolipoprotein A-IV; Apolipoprotein A4", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-8963888); (R-BTA-8963901); (R-BTA-975634)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding;GO:0005543 phospholipid binding;GO:0042803 protein homodimerization activity;GO:0016209 antioxidant activity;GO:0005507 copper ion binding", "go_cellular_component": "GO:0034364 high-density lipoprotein particle;GO:0042627 chylomicron;GO:0009986 cell surface;GO:0034361 very-low-density lipoprotein particle;GO:0034362 low-density lipoprotein particle", "go_biological_process": "GO:0006869 lipid transport;GO:0042157 lipoprotein metabolic process;GO:0006950 response to stress;GO:0008203 cholesterol metabolic process;GO:0010898 positive regulation of triglyceride catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N3Q7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6QLT4-1", "uniprot_id": "MTM1_BOVIN", "mass": 70020.0, "length": 603, "protein_name": "Myotubularin", "gene_name": "MTM1", "organism": "Bovine", "refseq_name": "myotubularin", "refseq_ac": "NP_001193354", "gene_names_uniprotkb": "MTM1", "gene_names_refseq": "MTM1", "protein_names_uniprotkb": "Myotubularin; 3.1.3.95; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; Phosphatidylinositol-3-phosphate phosphatase", "protein_names_refseq": "myotubularin; phosphatidylinositol-3,5-bisphosphate 3-phosphatase; phosphatidylinositol-3-phosphate phosphatase", "tax_id": 9913, "disease": "", "pathway": " (bta:533622); (R-BTA-1660499); (R-BTA-1660516); (R-BTA-1660517)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis. In skeletal muscles, stabilizes MTMR12 protein levels., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.95;3.1.3.64;3.1.3.67;3.1.3.86;3.1.3.36;3.1.3.-", "go_molecular_function": "GO:0035091 phosphatidylinositol binding;GO:0004721 phosphoprotein phosphatase activity;GO:0019215 intermediate filament binding;GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity;GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0005770 late endosome;GO:0030017 sarcomere", "go_biological_process": "GO:1902902 negative regulation of autophagosome assembly;GO:0015031 protein transport;GO:0046716 muscle cell cellular homeostasis;GO:0008333 endosome to lysosome transport;GO:0006470 protein dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6QLT4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MDT8-1", "uniprot_id": "F1MDT8_BOVIN", "mass": 286993.0, "length": 2563, "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "organism": "Bovine", "refseq_name": "LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD2", "refseq_ac": "XP_024839055", "gene_names_uniprotkb": "SETD2", "gene_names_refseq": "SETD2", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase SETD2; 2.1.1.359; Lysine N-methyltransferase 3A; Protein-lysine N-methyltransferase SETD2; SET domain-containing protein 2", "protein_names_refseq": "LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD2", "tax_id": 9913, "disease": "", "pathway": " (bta:539860)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.359;2.1.1.355;2.1.1.354;2.1.1.362;2.1.1.361;2.1.1.372;2.1.1.-;2.1.1.364;2.1.1.367;3.4.24.71", "go_molecular_function": "GO:0140955 histone H3K36 trimethyltransferase activity;GO:0046872 metal ion binding;GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0032259 methylation;GO:0032727 positive regulation of interferon-alpha production;GO:0034728 nucleosome organization;GO:1902850 microtubule cytoskeleton organization involved in mitosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MDT8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSV7-1", "uniprot_id": "F1MSV7_BOVIN", "mass": 53946.0, "length": 492, "protein_name": "Forkhead box protein P3", "gene_name": "FOXP3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FOXP3", "gene_names_refseq": "", "protein_names_uniprotkb": "Forkhead box protein P3", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-8877330)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding;GO:0051525 NFAT protein binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0032693 negative regulation of interleukin-10 production;GO:0002725 negative regulation of T cell cytokine production;GO:0032700 negative regulation of interleukin-17 production;GO:0032703 negative regulation of interleukin-2 production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSV7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G3X7P3-1", "uniprot_id": "G3X7P3_BOVIN", "mass": 92317.0, "length": 846, "protein_name": "Axin 2", "gene_name": "AXIN2", "organism": "Bovine", "refseq_name": "axin-2", "refseq_ac": "NP_001179228", "gene_names_uniprotkb": "AXIN2", "gene_names_refseq": "AXIN2", "protein_names_uniprotkb": "Axin 2", "protein_names_refseq": "axin 2 (conductin, axil); axin-2", "tax_id": 9913, "disease": "", "pathway": " (bta:511619); (R-BTA-201681); (R-BTA-4641257); (R-BTA-5689880)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019899 enzyme binding;GO:0060090 molecular adaptor activity;GO:0019901 protein kinase binding;GO:0031625 ubiquitin protein ligase binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005634 nucleus;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0016055 Wnt signaling pathway;GO:0048255 mRNA stabilization;GO:1903053 regulation of extracellular matrix organization;GO:0008104 intracellular protein localization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3X7P3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D3K0R6-1", "uniprot_id": "AT2B4_BOVIN", "mass": 133792.0, "length": 1207, "protein_name": "Plasma membrane calcium-transporting ATPase 4", "gene_name": "ATP2B4", "organism": "Bovine", "refseq_name": "plasma membrane calcium-transporting ATPase 4", "refseq_ac": "NP_001166065", "gene_names_uniprotkb": "ATP2B4", "gene_names_refseq": "ATP2B4; PMCA4", "protein_names_uniprotkb": "Plasma membrane calcium-transporting ATPase 4; 7.2.2.10; PMCA4", "protein_names_refseq": "ATPase, Ca++ transporting, plasma membrane 4 ATP synthase, H+ transporting, mitochondrial F1; plasma membrane calcium-transporting ATPase 4", "tax_id": 9913, "disease": "", "pathway": " (bta:282146); (R-BTA-418359); (R-BTA-5578775); (R-BTA-936837)", "pathway_count": 4, "publication_count": 5, "publication_id_list": "12552084;19393038;20050939;21187283;2966397", "class_list": "", "function": "Calcium/calmodulin-regulated and magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell (By similarity). By regulating sperm cells calcium homeostasis, may play a role in sperm motility (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Catalyzes the hydrolysis of ATP coupled with the transport of calcium., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Results indicate possible functional compartmentalization of PMCA in bull sperm membranes and point to a presumptive, interaction partner of Ca(2+)-ATPase and PDC-109., [RefSeq, PubMed]; Switch of PMCA4 splice variants in bovine epididymis results in altered isoform expression during functional sperm maturation., [RefSeq, PubMed]; Thermodynamic analysis of mitochondrial F1 ATPase, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D3K0R5;Q28059", "ec_number_list": "7.2.2.10;1.14.13.39;2.7.11.11", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0050998 nitric-oxide synthase binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0036126 sperm flagellum;GO:0030018 Z disc;GO:0030315 T-tubule", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0010629 negative regulation of gene expression;GO:0006874 intracellular calcium ion homeostasis;GO:0030317 flagellated sperm motility;GO:0051480 regulation of cytosolic calcium ion concentration", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "D3K0R6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1B8P9-1", "uniprot_id": "E1B8P9_BOVIN", "mass": 51027.0, "length": 443, "protein_name": "Mitogen-activated protein kinase", "gene_name": "MAPK3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MAPK3", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitogen-activated protein kinase; 2.7.11.24", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:531391); (R-BTA-110056); (R-BTA-112409); (R-BTA-1169408); (R-BTA-1181150); (R-BTA-1295596); (R-BTA-1502540); (R-BTA-162658); (R-BTA-170968); (R-BTA-198753); (R-BTA-202670); (R-BTA-2029482); (R-BTA-2173795); (R-BTA-2173796); (R-BTA-2559580); (R-BTA-2559582); (R-BTA-2559585); (R-BTA-2871796); (R-BTA-3371453); (R-BTA-375165); (R-BTA-445144); (R-BTA-450341); (R-BTA-456926); (R-BTA-5654726); (R-BTA-5654727); (R-BTA-5654732); (R-BTA-5654733); (R-BTA-5663213); (R-BTA-5668599); (R-BTA-5673001); (R-BTA-5674135); (R-BTA-5674499); (R-BTA-5675221); (R-BTA-6811558); (R-BTA-73728); (R-BTA-74749); (R-BTA-877300); (R-BTA-881907); (R-BTA-8939211); (R-BTA-9627069); (R-BTA-9732724); (R-BTA-982772); (R-BTA-9856649)", "pathway_count": 43, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;3.6.5.2;2.7.11.23;2.7.12.1;2.7.12.2;2.7.10.1;2.7.11.17;2.3.2.23;3.1.3.16;3.1.3.48;2.7.11.39;2.7.10.2;6.1.1.4;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;6.1.1.6;6.1.1.15;6.1.1.17;2.7.1.153;2.7.1.137;2.7.1.154;3.6.4.13;2.3.2.31;6.1.1.19;3.4.22.62;4.1.1.32;6.1.1.10;2.7.11.38;6.1.1.12;5.2.1.8;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;3.6.4.-;2.7.10.4;2.7.11.-;2.7.11.4;6.1.1.18;2.7.2.3;5.3.99.3;3.6.4.10;2.7.11.10", "go_molecular_function": "GO:0005524 ATP binding;GO:0004707 MAP kinase activity;GO:0106310 protein serine kinase activity;GO:0001784 phosphotyrosine residue binding;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005856 cytoskeleton;GO:0005925 focal adhesion;GO:0012505 endomembrane system", "go_biological_process": "GO:0009893 positive regulation of metabolic process;GO:0006915 apoptotic process;GO:1902531 regulation of intracellular signal transduction;GO:0010468 regulation of gene expression;GO:0051049 regulation of transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1B8P9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MDT6-1", "uniprot_id": "F1MDT6_BOVIN", "mass": 99229.0, "length": 879, "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GPAM", "gene_names_refseq": "", "protein_names_uniprotkb": "Glycerol-3-phosphate acyltransferase 1, mitochondrial; 2.3.1.15", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1483166); (R-BTA-75109)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mitochondrial membrane protein that catalyzes the essential first step of biosynthesis of glycerolipids such as triglycerides, phosphatidic acids and lysophosphatidic acids. Esterifies acyl-group from acyl-coenzyme A (acyl-CoA) to the sn-1 position of glycerol-3-phosphate, to produce lysophosphatidic acid. Has a narrow hydrophobic binding cleft that selects for a linear acyl chain. Catalytic activity is higher for substrates with a 16-carbon acyl chain., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.15", "go_molecular_function": "GO:0004366 glycerol-3-phosphate O-acyltransferase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005886 plasma membrane;GO:0005739 mitochondrion", "go_biological_process": "GO:0016024 CDP-diacylglycerol biosynthetic process;GO:0006650 glycerophospholipid metabolic process;GO:0019432 triglyceride biosynthetic process;GO:0006655 phosphatidylglycerol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MDT6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BAM5-1", "uniprot_id": "E1BAM5_BOVIN", "mass": 50465.0, "length": 480, "protein_name": "GATA binding protein 2", "gene_name": "GATA2", "organism": "Bovine", "refseq_name": "endothelial transcription factor GATA-2", "refseq_ac": "NP_001179043", "gene_names_uniprotkb": "GATA2", "gene_names_refseq": "GATA2", "protein_names_uniprotkb": "GATA binding protein 2", "protein_names_refseq": "endothelial transcription factor GATA-2", "tax_id": 9913, "disease": "", "pathway": " (bta:506809); (R-BTA-8939236); (R-BTA-983231)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "21606631", "class_list": "", "function": "GATA2 and/or GATA3 are involved in the regulation of trophoblast-specific gene transcription in bovine trophoblast CT-1 cells, [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0003682 chromatin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0035854 eosinophil fate commitment;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E1BAM5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G3MWR4-1", "uniprot_id": "G3MWR4_BOVIN", "mass": 35023.0, "length": 303, "protein_name": "Sodium/potassium-transporting ATPase subunit beta", "gene_name": "ATP1B1", "organism": "Bovine", "refseq_name": "sodium/potassium-transporting ATPase subunit beta-1", "refseq_ac": "NP_001421907", "gene_names_uniprotkb": "ATP1B1", "gene_names_refseq": "ATP1B1", "protein_names_uniprotkb": "Sodium/potassium-transporting ATPase subunit beta", "protein_names_refseq": "sodium/potassium-transporting ATPase subunit beta-1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5578775); (R-BTA-936837)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "19101784;27050261", "class_list": "", "function": "Biochemical and biophysical characteristics of the alpha(2)beta(1) isozyme of Na(+)/K(+)-ATPase from caveolae vesicles of pulmonary smooth muscle plasma membrane were studied during solubilization and purification, [RefSeq, PubMed]; Involved in cell adhesion and establishing epithelial cell polarity., [UniProtKB, UniProtKB, UniProtKB]; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0030674 protein-macromolecule adaptor activity;GO:0051117 ATPase binding;GO:0001671 ATPase activator activity;GO:0005391 P-type sodium:potassium-exchanging transporter activity", "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0042383 sarcolemma;GO:0005890 sodium:potassium-exchanging ATPase complex;GO:0016323 basolateral plasma membrane;GO:0014704 intercalated disc", "go_biological_process": "GO:0006813 potassium ion transport;GO:0006814 sodium ion transport;GO:0072659 protein localization to plasma membrane;GO:0006874 intracellular calcium ion homeostasis;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "G3MWR4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BDN7-1", "uniprot_id": "E1BDN7_BOVIN", "mass": 133309.0, "length": 1218, "protein_name": "Delta-like protein", "gene_name": "JAG1", "organism": "Bovine", "refseq_name": "protein jagged-1 precursor", "refseq_ac": "NP_001178107", "gene_names_uniprotkb": "JAG1", "gene_names_refseq": "JAG1", "protein_names_uniprotkb": "Delta-like protein", "protein_names_refseq": "jagged 1 (Alagille syndrome); protein jagged-1 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:783681); (R-BTA-9013423)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Putative Notch ligand involved in the mediation of Notch signaling., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005112 Notch binding;GO:0060090 molecular adaptor activity;GO:0005543 phospholipid binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0042491 inner ear auditory receptor cell differentiation;GO:0010557 positive regulation of macromolecule biosynthetic process;GO:0007219 Notch signaling pathway;GO:0042127 regulation of cell population proliferation;GO:0045597 positive regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BDN7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A2VDZ3-1", "uniprot_id": "MEF2A_BOVIN", "mass": 52782.0, "length": 492, "protein_name": "Myocyte-specific enhancer factor 2A", "gene_name": "MEF2A", "organism": "Bovine", "refseq_name": "myocyte-specific enhancer factor 2A", "refseq_ac": "NP_001077107", "gene_names_uniprotkb": "MEF2A", "gene_names_refseq": "MEF2A", "protein_names_uniprotkb": "Myocyte-specific enhancer factor 2A", "protein_names_refseq": "myocyte-specific enhancer factor 2A", "tax_id": 9913, "disease": "", "pathway": " (bta:407231)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "22320864;29698438;37510401", "class_list": "", "function": "Effect of Bovine MEF2A Gene Expression on Proliferation and Apoptosis of Myoblast Cells. Publication Status: Online-Only, [RefSeq, PubMed]; MEF2A is a positive regulator in skeletal muscle myoblast proliferation Publication Status: Online-Only, [RefSeq, PubMed]; Polymorphisms in the bovine MEF2A gene and their effect on the MEF2A mRNA expression level in the longissimus dorsi muscle, [RefSeq, PubMed]; Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0019901 protein kinase binding;GO:0046982 protein heterodimerization activity;GO:0042826 histone deacetylase binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex;GO:0000785 chromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0010628 positive regulation of gene expression;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A2VDZ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MQ78-1", "uniprot_id": "F1MQ78_BOVIN", "mass": 77865.0, "length": 674, "protein_name": "Polyunsaturated fatty acid 5-lipoxygenase", "gene_name": "ALOX5", "organism": "Bovine", "refseq_name": "polyunsaturated fatty acid 5-lipoxygenase", "refseq_ac": "NP_001179721", "gene_names_uniprotkb": "ALOX5", "gene_names_refseq": "ALOX5", "protein_names_uniprotkb": "Polyunsaturated fatty acid 5-lipoxygenase; 1.13.11.12; 1.13.11.34; 12/15-lipoxygenase; Arachidonate 12-lipoxygenase, leukocyte-type; Arachidonate 15-lipoxygenase; Arachidonate 5-lipoxygenase; Arachidonate omega-6 lipoxygenase; Erythroid cell-specific 15-lipoxygenase; Hepoxilin A3 synthase Alox15; Linoleate 13S-lipoxygenase; Polyunsaturated fatty acid lipoxygenase ALOX15", "protein_names_refseq": "polyunsaturated fatty acid 5-lipoxygenase", "tax_id": 9913, "disease": "", "pathway": " (bta:404074); (R-BTA-2142688); (R-BTA-2142691); (R-BTA-2142700); (R-BTA-6798695); (R-BTA-9018676); (R-BTA-9018682); (R-BTA-9018896); (R-BTA-9020265); (R-BTA-9023661); (R-BTA-9026286); (R-BTA-9026290); (R-BTA-9026403); (R-BTA-9027604)", "pathway_count": 14, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.42;2.5.1.18;2.7.1.1;2.7.11.24;2.7.11.1;3.2.1.23;2.4.2.1;5.2.1.8;4.1.2.13;3.6.1.6;1.13.11.31;2.3.2.27;3.1.6.14;3.6.4.13;1.1.1.205;2.7.1.11;2.7.11.22;2.7.11.23;1.13.11.12;2.3.2.26;1.13.11.33;2.4.1.25;3.2.1.33;4.2.99.18;5.6.2.4;3.6.4.12;3.4.23.5;1.13.11.34;3.6.4.6;1.16.3.1;1.11.1.6;3.4.18.1;3.4.22.1;3.6.4.10;3.4.22.27;1.13.11.-;3.4.24.35;3.6.5.-;3.1.1.47;5.3.2.1;5.3.3.12;3.4.19.1;2.7.1.35;2.4.1.1;3.5.1.23;3.5.1.-;3.4.22.52;4.4.1.20;2.5.1.-;2.3.3.8;5.4.2.11;5.4.2.4;3.3.2.6;3.4.11.4;3.4.21.46;2.7.4.6;2.7.13.3;4.1.2.4;5.3.1.9;5.1.3.-;3.6.1.-;2.4.2.7;4.2.1.24", "go_molecular_function": "GO:0005506 iron ion binding;GO:0016787 hydrolase activity;GO:0008289 lipid binding;GO:0004052 arachidonate 12(S)-lipoxygenase activity;GO:0016165 linoleate 13S-lipoxygenase activity", "go_cellular_component": "GO:0005641 nuclear envelope lumen;GO:0005811 lipid droplet;GO:0005829 cytosol;GO:0031965 nuclear membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0034440 lipid oxidation;GO:0006950 response to stress;GO:0019370 leukotriene biosynthetic process;GO:0061044 negative regulation of vascular wound healing;GO:2001301 lipoxin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MQ78-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N215-1", "uniprot_id": "F1N215_BOVIN", "mass": 173154.0, "length": 1612, "protein_name": "GLI family zinc finger 3", "gene_name": "GLI3", "organism": "Bovine", "refseq_name": "transcriptional activator GLI3 isoform X1", "refseq_ac": "XP_059741905", "gene_names_uniprotkb": "GLI3", "gene_names_refseq": "GLI3", "protein_names_uniprotkb": "GLI family zinc finger 3", "protein_names_refseq": "transcriptional activator GLI3 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5610785); (R-BTA-5610787); (R-BTA-5632684)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0003682 chromatin binding;GO:0042826 histone deacetylase binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0017053 transcription repressor complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007224 smoothened signaling pathway;GO:0009653 anatomical structure morphogenesis;GO:0046639 negative regulation of alpha-beta T cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N215-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MDC9-1", "uniprot_id": "F1MDC9_BOVIN", "mass": 83633.0, "length": 737, "protein_name": "Protein kinase C epsilon type", "gene_name": "PRKCE", "organism": "Bovine", "refseq_name": "protein kinase C epsilon type", "refseq_ac": "NP_001104590", "gene_names_uniprotkb": "PRKCE", "gene_names_refseq": "PRKCE", "protein_names_uniprotkb": "Protein kinase C epsilon type; 2.7.11.13; nPKC-epsilon", "protein_names_refseq": "PKC-epsilon; protein kinase C epsilon type", "tax_id": 9913, "disease": "", "pathway": " (bta:507041)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "17760987;18323518;19913548;22677421", "class_list": "", "function": "By regulating VEGFR2 expression and activation, PKC-epsilon expression is critical for activation of Akt and eNOS by VEGF and contributes to VEGF-stimulated Erk activation, whereas PKC-alpha has opposite effects., [RefSeq, PubMed]; Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 (ITGB1) in cardiac fibroblasts. Phosphorylates MARCKS, which phosphorylates and activates PTK2/FAK, leading to the spread of cardiomyocytes. Involved in the control of the directional transport of ITGB1 in mesenchymal cells by phosphorylating vimentin (VIM), an intermediate filament (IF) protein. In epithelial cells, associates with and phosphorylates keratin-8 (KRT8), which induces targeting of desmoplakin at desmosomes and regulates cell-cell contact. Phosphorylates IQGAP1, which binds to CDC42, mediating epithelial cell-cell detachment prior to migration., [UniProtKB, UniProtKB]; DeltaPKC inhibition or varepsilonPKC activation repairs endothelial vascular dysfunction by regulating eNOS post-translational modification, [RefSeq, PubMed]; Differential expression of protein kinase C epsilon and an elevation of [Ca(2+)]i are important for acquisition of luteolytic response to PGF2 alpha Publication Status: Online-Only, [RefSeq, PubMed]; These data identify PKCepsilon as a key regulator of cilia slowing in response to combined smoke and alcohol-induced lung injury., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0004697 diacylglycerol-dependent serine/threonine kinase activity;GO:0106310 protein serine kinase activity;GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0035669 TRAM-dependent toll-like receptor 4 signaling pathway;GO:0007155 cell adhesion;GO:0051301 cell division;GO:0090303 positive regulation of wound healing;GO:0042178 xenobiotic catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1MDC9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P02070-1", "uniprot_id": "HBB_BOVIN", "mass": 15954.0, "length": 145, "protein_name": "Hemoglobin subunit beta", "gene_name": "HBB", "organism": "Bovine", "refseq_name": "hemoglobin subunit beta", "refseq_ac": "NP_776342", "gene_names_uniprotkb": "HBB", "gene_names_refseq": "GLNA1; HBB", "protein_names_uniprotkb": "Hemoglobin subunit beta; Beta-globin; Hemoglobin beta chain", "protein_names_refseq": "beta globin; globin A1; hemoglobin beta chain; hemoglobin subunit beta", "tax_id": 9913, "disease": "", "pathway": " (bta:280813); (R-BTA-1237044); (R-BTA-1247673); (R-BTA-2168880); (R-BTA-6798695); (R-BTA-9707564); (R-BTA-9707616)", "pathway_count": 7, "publication_count": 8, "publication_id_list": "11369847;17718518;23991043;4561255;6048711;6322113;8343155;8411160", "class_list": "", "function": "Data indicate that on incubating hemoglobin with glyoxal for 0-20 days, advanced glycation end products (AGEs) were detected on day 20. Publication Status: Online-Only, [RefSeq, PubMed]; Functions as an endogenous inhibitor of enkephalin-degrading enzymes such as DPP3, and may thereby play a role as a regulator of pain and inflammation., [UniProtKB, PubMed]; Involved in oxygen transport from the lung to the various peripheral tissues., [UniProtKB, PubMed]; The acid-induced denaturation of Hb follows a highly symmetric mechanism., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0031721 hemoglobin alpha binding;GO:0019825 oxygen binding;GO:0005344 oxygen carrier activity", "go_cellular_component": "GO:0005833 hemoglobin complex;GO:0031838 haptoglobin-hemoglobin complex", "go_biological_process": "GO:0048821 erythrocyte development;GO:0015671 oxygen transport", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P02070-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MKA9-1", "uniprot_id": "F1MKA9_BOVIN", "mass": 76742.0, "length": 680, "protein_name": "Tumor protein 63 (p63)", "gene_name": "TP63", "organism": "Bovine", "refseq_name": "tumor protein 63", "refseq_ac": "NP_001178266", "gene_names_uniprotkb": "TP63", "gene_names_refseq": "TP63", "protein_names_uniprotkb": "Tumor protein 63 (p63)", "protein_names_refseq": "tumor protein 63", "tax_id": 9913, "disease": "", "pathway": " (bta:615335); (R-BTA-6804759)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Multifunctional transcription factor that induces cell cycle arrest, DNA repair or apoptosis upon binding to its target DNA sequence. Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Negatively regulates cell division by controlling expression of a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046872 metal ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0042802 identical protein binding;GO:0050699 WW domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005813 centrosome;GO:0005654 nucleoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0051262 protein tetramerization;GO:0006915 apoptotic process;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0061436 establishment of skin barrier", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MKA9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6H772-1", "uniprot_id": "PP4C_BOVIN", "mass": 35080.0, "length": 307, "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "organism": "Bovine", "refseq_name": "serine/threonine-protein phosphatase 4 catalytic subunit", "refseq_ac": "NP_001092578", "gene_names_uniprotkb": "PPP4C", "gene_names_refseq": "PPP4C", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 4 catalytic subunit; 3.1.3.16; PP4C; Pp4", "protein_names_refseq": "PP4C; pp4; protein phosphatase 4 (formerly X), catalytic subunit; serine/threonine-protein phosphatase 4 catalytic subunit", "tax_id": 9913, "disease": "", "pathway": " (bta:540398); (R-BTA-5693607)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on Ser-140 (gamma-H2AX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase. In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.16;3.1.3.48;3.1.3.67;3.1.3.74;3.1.3.52;3.1.3.53", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0000724 double-strand break repair via homologous recombination;GO:0010569 regulation of double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6H772-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O46629-1", "uniprot_id": "ECHB_BOVIN", "mass": 51345.0, "length": 475, "protein_name": "Trifunctional enzyme subunit beta, mitochondrial", "gene_name": "HADHB", "organism": "Bovine", "refseq_name": "trifunctional enzyme subunit beta, mitochondrial precursor", "refseq_ac": "NP_776761", "gene_names_uniprotkb": "HADHB", "gene_names_refseq": "HADHB", "protein_names_uniprotkb": "Trifunctional enzyme subunit beta, mitochondrial; 3-oxoacyl-CoA thiolase; Acetyl-CoA acyltransferase; Beta-ketothiolase; LCKAT; Long chain 3-ketoacyl-CoA thiolase; TP-beta", "protein_names_refseq": "TP-beta; dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit; hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit; mitochondrial trifunctional protein, beta subunit; trifunctional enzyme subunit beta, mitochondrial precursor; trifunctional enzyme subunit beta, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:281811); (R-BTA-1482798); (R-BTA-77285); (R-BTA-77305); (R-BTA-77310); (R-BTA-77346); (R-BTA-77348); (R-BTA-77350)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "17143551", "class_list": "", "function": "Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional enzyme subunit alpha/HADHA carries the 2,3-enoyl-CoA hydratase and the 3-hydroxyacyl-CoA dehydrogenase activities, while the trifunctional enzyme subunit beta/HADHB described here bears the 3-ketoacyl-CoA thiolase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Mutation analysis of the HADHB gene of patient 4 identified compound heterozygosity of N114D/N307D., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3SZZ3", "ec_number_list": "2.3.1.176;2.3.1.16;2.3.1.155;3.1.2.-;3.1.2.2;3.1.2.1;2.3.1.9", "go_molecular_function": "GO:0003985 acetyl-CoA C-acetyltransferase activity;GO:0050633 acetyl-CoA C-myristoyltransferase activity;GO:0003988 acetyl-CoA C-acyltransferase activity;GO:0106222 lncRNA binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005743 mitochondrial inner membrane;GO:0005783 endoplasmic reticulum;GO:0016507 mitochondrial fatty acid beta-oxidation multienzyme complex;GO:0005739 mitochondrion", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0006631 fatty acid metabolic process;GO:0071222 cellular response to lipopolysaccharide;GO:0010467 gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O46629-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BIY5-1", "uniprot_id": "E1BIY5_BOVIN", "mass": 99818.0, "length": 865, "protein_name": "Arylsulfatase", "gene_name": "SULF2", "organism": "Bovine", "refseq_name": "extracellular sulfatase Sulf-2 isoform X1", "refseq_ac": "XP_005214813", "gene_names_uniprotkb": "SULF2", "gene_names_refseq": "SULF2", "protein_names_uniprotkb": "Arylsulfatase; 3.1.6.14; 3.1.6.1; N-acetylglucosamine-6-sulfatase", "protein_names_refseq": "extracellular sulfatase Sulf-2 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.6.14;3.1.6.1;3.1.6.-;3.1.6.15;3.1.6.18", "go_molecular_function": "GO:0008449 N-acetylglucosamine-6-sulfatase activity;GO:0005509 calcium ion binding;GO:0004065 arylsulfatase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0009986 cell surface;GO:0005795 Golgi stack;GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0060384 innervation;GO:0014846 esophagus smooth muscle contraction;GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway;GO:0010575 positive regulation of vascular endothelial growth factor production;GO:0060348 bone development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BIY5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N1I6-1", "uniprot_id": "F1N1I6_BOVIN", "mass": 92084.0, "length": 846, "protein_name": "Gelsolin", "gene_name": "GSN", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GSN", "gene_names_refseq": "", "protein_names_uniprotkb": "Gelsolin; ADF; Actin-depolymerizing factor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-264870); (R-BTA-6798695)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0051015 actin filament binding;GO:0045159 myosin II binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0007015 actin filament organization;GO:0051016 barbed-end actin filament capping;GO:0060271 cilium assembly;GO:0051014 actin filament severing;GO:0014891 striated muscle atrophy", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N1I6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MC14-1", "uniprot_id": "F1MC14_BOVIN", "mass": 89900.0, "length": 821, "protein_name": "Tyrosine-protein kinase receptor", "gene_name": "NTRK1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NTRK1", "gene_names_refseq": "", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor; 2.7.10.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1257604); (R-BTA-170968); (R-BTA-170984); (R-BTA-177504); (R-BTA-187042); (R-BTA-198203)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.1;2.7.1.153;2.7.1.137;3.6.5.2;2.7.10.4", "go_molecular_function": "GO:0043121 neurotrophin binding;GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity;GO:0005030 neurotrophin receptor activity;GO:0048406 nerve growth factor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0043235 receptor complex;GO:0031902 late endosome membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0010976 positive regulation of neuron projection development;GO:0031175 neuron projection development;GO:0043066 negative regulation of apoptotic process;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MC14-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F6Q6K1-1", "uniprot_id": "F6Q6K1_BOVIN", "mass": 76318.0, "length": 677, "protein_name": "Serine/threonine-protein kinase CHK1", "gene_name": "CHEK1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CHEK1", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein kinase CHK1; 2.7.11.1; CHK1 checkpoint homolog; Checkpoint kinase-1; Serine/threonine-protein kinase Chk1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0035402 histone H3T11 kinase activity;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005694 chromosome;GO:0000794 condensed nuclear chromosome;GO:0005654 nucleoplasm", "go_biological_process": "GO:0000077 DNA damage checkpoint signaling;GO:0046602 regulation of mitotic centrosome separation;GO:0006281 DNA repair;GO:0035556 intracellular signal transduction;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6Q6K1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00794-1", "uniprot_id": "CHYM_BOVIN", "mass": 42180.0, "length": 381, "protein_name": "Chymosin", "gene_name": "CYM", "organism": "Bovine", "refseq_name": "chymosin preproprotein", "refseq_ac": "NP_851337", "gene_names_uniprotkb": "CYM; CPC", "gene_names_refseq": "CPC; CYM; Chy", "protein_names_uniprotkb": "Chymosin; 3.4.23.4; Preprorennin", "protein_names_refseq": "chymosin preproprotein; preprorennin; prochymosin; rennin", "tax_id": 9913, "disease": "", "pathway": " (bta:529879)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "1530626;1942052;20155951;2217166;2271625;23633601;240697;2415509;3091454;329280;381305;4612029;6183168;6283469;6804449", "class_list": "", "function": "Chymosin is synthesized in the mucosa of the abomasum (fourth stomach) of young (unweaned) ruminants. The enzyme hydrolyzes casein to paracasein., [UniProtKB]; Crystal structure of bovine chymosin shows relationship with cheese making properties, [RefSeq, PubMed]; Molecular dynamics simulation of bovine chymosin complexed with the P9-P70 residues of bovine kappa-casein, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8RRP5", "ec_number_list": "", "go_molecular_function": "GO:0004190 aspartic-type endopeptidase activity", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0007586 digestion", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P00794-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A2VDN5-1", "uniprot_id": "SPAST_BOVIN", "mass": 67225.0, "length": 614, "protein_name": "Spastin", "gene_name": "SPAST", "organism": "Bovine", "refseq_name": "spastin", "refseq_ac": "NP_001075060", "gene_names_uniprotkb": "SPAST; SPG4", "gene_names_refseq": "SPAST; SPG4", "protein_names_uniprotkb": "Spastin; 5.6.1.1", "protein_names_refseq": "spastin", "tax_id": 9913, "disease": "", "pathway": " (bta:521442); (R-BTA-9668328)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "19714378", "class_list": "", "function": "ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. It is critical for the biogenesis and maintenance of complex microtubule arrays in axons, spindles and cilia. SPAST is involved in abscission step of cytokinesis and nuclear envelope reassembly during anaphase in cooperation with the ESCRT-III complex. Recruited at the midbody, probably by IST1, and participates in membrane fission during abscission together with the ESCRT-III complex. Recruited to the nuclear membrane by IST1 and mediates microtubule severing, promoting nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and endosome recycling. Recruited by IST1 to endosomes and regulates early endosomal tubulation and recycling by mediating microtubule severing. Probably plays a role in axon growth and the formation of axonal branches., [UniProtKB, HAMAP, UniProtKB]; Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX-dependent manner. May regulate osteoblast proliferation and differentiation. May play a role in the control of male meiosis dynamic., [UniProtKB, UniProtKB]; Results demonstrate a causal relationship between the SPAST mutation and bovine spinal dysmyelination. GeneRIF: A defective SPAST gene in cattle is associated with a recessive, congenital neurodegenerative disease, which is characterized by pathological changes of the myelin sheaths in the spinal cord., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.1.1;3.6.4.6", "go_molecular_function": "GO:0008568 microtubule severing ATPase activity;GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0048487 beta-tubulin binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005768 endosome", "go_biological_process": "GO:0031468 nuclear membrane reassembly;GO:0051013 microtubule severing;GO:0031117 positive regulation of microtubule depolymerization;GO:0051260 protein homooligomerization;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A2VDN5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSX5-1", "uniprot_id": "F1MSX5_BOVIN", "mass": 50883.0, "length": 467, "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TNFRSF1A", "gene_names_refseq": "", "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; Tumor necrosis factor receptor type I; p55; p60", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5357786); (R-BTA-5357905); (R-BTA-5357956); (R-BTA-5626978); (R-BTA-5669034); (R-BTA-75893)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043120 tumor necrosis factor binding;GO:0005031 tumor necrosis factor receptor activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0043235 receptor complex;GO:0045121 membrane raft;GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0006915 apoptotic process;GO:0006693 prostaglandin metabolic process;GO:1903140 regulation of establishment of endothelial barrier;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSX5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5D7D1-1", "uniprot_id": "ACTN4_BOVIN", "mass": 104928.0, "length": 911, "protein_name": "Alpha-actinin-4", "gene_name": "ACTN4", "organism": "Bovine", "refseq_name": "alpha-actinin-4", "refseq_ac": "NP_001091521", "gene_names_uniprotkb": "ACTN4", "gene_names_refseq": "ACTN4", "protein_names_uniprotkb": "Alpha-actinin-4; Non-muscle alpha-actinin 4", "protein_names_refseq": "F-actin cross-linking protein; alpha-actinin-4; non-muscle alpha-actinin 4", "tax_id": 9913, "disease": "", "pathway": " (bta:522269); (R-BTA-114608)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "30573663", "class_list": "", "function": "F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions. May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA. Association with IGSF8 regulates the immune synapse formation and is required for efficient T-cell activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0051015 actin filament binding;GO:0005509 calcium ion binding;GO:0003779 actin binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030054 cell junction;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0015031 protein transport;GO:0030036 actin cytoskeleton organization;GO:0048384 retinoic acid receptor signaling pathway;GO:0035357 peroxisome proliferator activated receptor signaling pathway;GO:0055001 muscle cell development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A5D7D1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MBS5-1", "uniprot_id": "F1MBS5_BOVIN", "mass": 95009.0, "length": 877, "protein_name": "Lysine-specific histone demethylase", "gene_name": "KDM1A", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "KDM1A", "gene_names_refseq": "", "protein_names_uniprotkb": "Lysine-specific histone demethylase; 1.14.99.66", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3214815); (R-BTA-3214842); (R-BTA-5625886); (R-BTA-9018519); (R-BTA-9764725); (R-BTA-983231)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Histone demethylase that can demethylate both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Neuron-specific histone demethylase that demethylates mono- and dimethylated 'Lys-20' of histone H4 (H4K20me1 and H4K20me2), a chromatin repressive mark. This demethylation is crucial for the initiation and elongation of neuronal activity-regulated genes, required for spatial learning and memory. Mediates H3K9me2 demethylation through cooperation with the supervillin protein (SVIL), and this H3K9 demethylase activity is essential for regulating gene expression during neuronal differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.99.66;1.14.11.65;2.7.11.13;1.14.11.-;3.5.1.-;3.5.1.98", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0003723 RNA binding;GO:0019899 enzyme binding;GO:0050660 flavin adenine dinucleotide binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0035097 histone methyltransferase complex;GO:1990391 DNA repair complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045597 positive regulation of cell differentiation;GO:2000179 positive regulation of neural precursor cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MBS5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F6QK60-1", "uniprot_id": "F6QK60_BOVIN", "mass": 50176.0, "length": 457, "protein_name": "NAD-dependent protein deacetylase sirtuin-2", "gene_name": "SIRT2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SIRT2", "gene_names_refseq": "", "protein_names_uniprotkb": "NAD-dependent protein deacetylase sirtuin-2; 2.3.1.286; NAD-dependent protein deacylase sirtuin-2; NAD-dependent protein defatty-acylase sirtuin-2; Regulatory protein SIR2 homolog 2; SIR2-like protein 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2995383)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.286", "go_molecular_function": "GO:0046872 metal ion binding;GO:0070403 NAD+ binding;GO:0033558 protein lysine deacetylase activity;GO:0034979 NAD-dependent protein lysine deacetylase activity;GO:0140773 NAD-dependent protein demyristoylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0043209 myelin sheath;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005739 mitochondrion", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0051239 regulation of multicellular organismal process;GO:0045836 positive regulation of meiotic nuclear division;GO:0061433 cellular response to caloric restriction;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6QK60-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5PJP6-1", "uniprot_id": "BRCC3_BOVIN", "mass": 36152.0, "length": 316, "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "organism": "Bovine", "refseq_name": "lys-63-specific deubiquitinase BRCC36 isoform 1", "refseq_ac": "NP_001069258", "gene_names_uniprotkb": "BRCC3; BRCC36", "gene_names_refseq": "BRCC3; CXorf53", "protein_names_uniprotkb": "Lys-63-specific deubiquitinase BRCC36; 3.4.19.-; BRCA1-A complex subunit BRCC36; BRCA1/BRCA2-containing complex subunit 36; BRCA1/BRCA2-containing complex subunit 3; BRISC complex subunit BRCC36", "protein_names_refseq": "BRCA1-A complex subunit BRCC36; BRCA1/BRCA2-containing complex subunit 36; BRISC complex subunit BRCC36; lys-63-specific deubiquitinase BRCC36 isoform 1; lys-63-specific deubiquitinase BRCC36", "tax_id": 9913, "disease": "", "pathway": " (bta:519513); (R-BTA-5689901); (R-BTA-5693565); (R-BTA-5693571); (R-BTA-5693607); (R-BTA-69473)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1., [UniProtKB, UniProtKB]; Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, antagonizing the RNF8-dependent ubiquitination at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1. Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activity by enhancing its stability and cell surface expression (By similarity). Acts as a regulator of the NLRP3 inflammasome by mediating deubiquitination of NLRP3, leading to NLRP3 inflammasome assembly (By similarity). Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination (By similarity). Deubiquitinates HDAC1 and PWWP2B leading to their stabilization (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q58D60", "ec_number_list": "2.3.1.48;2.3.2.27;3.4.19.-;3.6.4.-;2.3.2.26;2.7.11.1;2.1.1.357;2.3.2.23", "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0031593 polyubiquitin modification-dependent protein binding;GO:0046872 metal ion binding;GO:0030234 enzyme regulator activity;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0070552 BRISC complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006508 proteolysis;GO:0051301 cell division;GO:0070536 protein K63-linked deubiquitination;GO:0006302 double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A5PJP6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MT42-1", "uniprot_id": "F1MT42_BOVIN", "mass": 78030.0, "length": 695, "protein_name": "Follicle-stimulating hormone receptor", "gene_name": "FSHR", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FSHR", "gene_names_refseq": "", "protein_names_uniprotkb": "Follicle-stimulating hormone receptor; Follitropin receptor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-375281); (R-BTA-418555)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004963 follicle-stimulating hormone receptor activity;GO:0004930 G protein-coupled receptor activity;GO:0008528 G protein-coupled peptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0009986 cell surface;GO:0043235 receptor complex", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0008584 male gonad development;GO:0009755 hormone-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MT42-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N4R0-1", "uniprot_id": "F1N4R0_BOVIN", "mass": 77257.0, "length": 702, "protein_name": "Potassium voltage-gated channel subfamily KQT member 1", "gene_name": "KCNQ1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "KCNQ1", "gene_names_refseq": "", "protein_names_uniprotkb": "Potassium voltage-gated channel subfamily KQT member 1; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; KQT-like 1; Voltage-gated potassium channel subunit Kv7.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1296072); (R-BTA-5576890); (R-BTA-5576893)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.-.-", "go_molecular_function": "GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization;GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;GO:0015271 outward rectifier potassium channel activity;GO:0005516 calmodulin binding;GO:0005249 voltage-gated potassium channel activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0016323 basolateral plasma membrane;GO:0045121 membrane raft;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential;GO:0001508 action potential;GO:0097623 potassium ion export across plasma membrane;GO:0051049 regulation of transport;GO:0042391 regulation of membrane potential", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N4R0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O02703-1", "uniprot_id": "BAX_BOVIN", "mass": 21259.0, "length": 192, "protein_name": "Apoptosis regulator BAX", "gene_name": "BAX", "organism": "Bovine", "refseq_name": "apoptosis regulator BAX", "refseq_ac": "NP_776319", "gene_names_uniprotkb": "BAX", "gene_names_refseq": "BAX", "protein_names_uniprotkb": "Apoptosis regulator BAX", "protein_names_refseq": "BCL2-associated X protein; apoptosis regulator BAX", "tax_id": 9913, "disease": "", "pathway": " (bta:280730); (R-BTA-111457); (R-BTA-111458); (R-BTA-111461); (R-BTA-111463); (R-BTA-111469); (R-BTA-114294); (R-BTA-5620971); (R-BTA-6804114)", "pathway_count": 9, "publication_count": 6, "publication_id_list": "15068062;18272300;18962879;23755802;24085451;9501056", "class_list": "", "function": "Apoptosis-inducing factor was expressed in luminal alveolar cells and, in concert with a change in bax protein to bcl-2 protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses, [RefSeq, PubMed]; BoHV-5 replication apparently modulates BCL-2 expression and gene transcription, enhancing production of virus progeny, but does not increase Bax expression. Publication Status: Online-Only, [RefSeq, PubMed]; It was concluded that the Fas-FasL signaling pathway was involved in regulation of bovine oocyte apoptosis, perhaps related to B cell lymphoma/leukemia-2 associated X upregulation., [RefSeq, PubMed]; MRNA expression of Bax, Bcl-2, caspase-3 and-7 cannot be used as a reliable apoptosis detection method., [RefSeq, PubMed]; Plays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM). Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis., [UniProtKB, UniProtKB]; The effect of culture conditions on expression of heat shock protein 70 and Bax protein in bovine blastocysts is reported., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0008289 lipid binding;GO:0015267 channel activity;GO:0051434 BH3 domain binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0032091 negative regulation of protein binding;GO:0051881 regulation of mitochondrial membrane potential;GO:0097190 apoptotic signaling pathway;GO:0031334 positive regulation of protein-containing complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "O02703-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01289-1", "uniprot_id": "TKN1_BOVIN", "mass": 15076.0, "length": 130, "protein_name": "Protachykinin-1", "gene_name": "TAC1", "organism": "Bovine", "refseq_name": "protachykinin-1 preproprotein", "refseq_ac": "NP_776618", "gene_names_uniprotkb": "TAC1; NKA; NKNA; TAC2", "gene_names_refseq": "PPT; TAC1; TAC; beta-PPT-A", "protein_names_uniprotkb": "Protachykinin-1; Neuromedin L; PPT; Substance K", "protein_names_refseq": "neurokinin 1; neurokinin 2; neurokinin alpha; neuromedin L; neuropeptide K; neuropeptide gamma; protachykinin-1 preproprotein; substance K; substance P", "tax_id": 9913, "disease": "", "pathway": " (bta:281512); (R-BTA-380095); (R-BTA-416476)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "1708336;20378186;2809597;6083453;6195531", "class_list": "", "function": "Is a ligand for TACR1, and triggers G protein-coupled receptor signaling via activation of phosphatidylinositol hydrolysis by phospholipase C. Substance P binding to TACR1 also triggers signaling via activation of adenylate cyclase activity which results in increased intracellular levels of cyclic AMP (cAMP) (By similarity). Is also a TACR3 agonist with low receptor affinity (By similarity). Basic secretagogue neuropeptide released from the terminals of specific sensory nerves. Acts as a ligand for MRGPRX2 receptor in mast cells, initiating a signaling that mediates neurogenic inflammation and pain (By similarity). Neurogenic inflammation includes mast cell activation, recruitment of immune cells and release of inflammatory mediators, such as cytokines and chemokines (By similarity). The inflammatory response can then activate or sensitize nociceptors, promoting pain (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Is a ligand for TACR2, and triggers G protein-coupled receptor signaling via activation of G(q) and phosphatidylinositol hydrolysis by phospholipase C. Binding to TACR2 also triggers signaling via activation of adenylate cyclase activity which results in increased intracellular levels of cyclic AMP (cAMP)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Substance P alters the cytokine and chemokine expression pattern in monocytes and blood-monocyte-derived macrophages., [RefSeq, PubMed]; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5PK57;B0JYM8;P01291;P04091;P20773", "ec_number_list": "", "go_molecular_function": "GO:0031835 substance P receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0030424 axon;GO:0043025 neuronal cell body;GO:0045202 synapse", "go_biological_process": "GO:0006954 inflammatory response;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0007218 neuropeptide signaling pathway;GO:0007268 chemical synaptic transmission;GO:0019233 sensory perception of pain", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P01289-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MPE9-1", "uniprot_id": "F1MPE9_BOVIN", "mass": 265337.0, "length": 2471, "protein_name": "Neurogenic locus notch homolog protein 2", "gene_name": "NOTCH2", "organism": "Bovine", "refseq_name": "neurogenic locus notch homolog protein 2 isoform X1", "refseq_ac": "XP_002686160", "gene_names_uniprotkb": "NOTCH2", "gene_names_refseq": "NOTCH2", "protein_names_uniprotkb": "Neurogenic locus notch homolog protein 2", "protein_names_refseq": "neurogenic locus notch homolog protein 2 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:513730)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation. Positively regulates self-renewal of liver cancer cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0038023 signaling receptor activity;GO:0003713 transcription coactivator activity;GO:0019899 enzyme binding;GO:0051059 NF-kappaB binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005654 nucleoplasm;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0048731 system development;GO:0050793 regulation of developmental process;GO:0071228 cellular response to tumor cell;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MPE9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01888-1", "uniprot_id": "B2MG_BOVIN", "mass": 13677.0, "length": 118, "protein_name": "Beta-2-microglobulin", "gene_name": "B2M", "organism": "Bovine", "refseq_name": "beta-2-microglobulin precursor", "refseq_ac": "NP_776318", "gene_names_uniprotkb": "B2M", "gene_names_refseq": "B2M", "protein_names_uniprotkb": "Beta-2-microglobulin; Lactollin", "protein_names_refseq": "beta-2-microglobulin precursor; lactollin", "tax_id": 9913, "disease": "", "pathway": " (bta:280729); (bta:783680); (R-BTA-1236974); (R-BTA-1236977); (R-BTA-198933); (R-BTA-2424491); (R-BTA-6798695); (R-BTA-983170)", "pathway_count": 8, "publication_count": 4, "publication_id_list": "23613577;3889925;6174509;8319984", "class_list": "", "function": "Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q148G6;Q56K05", "ec_number_list": "", "go_molecular_function": "GO:0023026 MHC class II protein complex binding;GO:0042605 peptide antigen binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0042613 MHC class II protein complex;GO:0042612 MHC class I protein complex", "go_biological_process": "GO:0006955 immune response;GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002474 antigen processing and presentation of peptide antigen via MHC class I;GO:0002503 peptide antigen assembly with MHC class II protein complex;GO:0050870 positive regulation of T cell activation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P01888-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MM10-1", "uniprot_id": "F1MM10_BOVIN", "mass": 58804.0, "length": 516, "protein_name": "Cytochrome P450 1A", "gene_name": "CYP1A1", "organism": "Bovine", "refseq_name": "cytochrome P450 1A1", "refseq_ac": "XP_002696681", "gene_names_uniprotkb": "CYP1A1", "gene_names_refseq": "CYP1A1", "protein_names_uniprotkb": "Cytochrome P450 1A; 1.14.14.1", "protein_names_refseq": "cytochrome P450 1A1", "tax_id": 9913, "disease": "", "pathway": " (bta:282870); (R-BTA-211981); (R-BTA-2142670); (R-BTA-2142816); (R-BTA-9018681)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.2.1.152;5.3.99.5;1.14.14.1;1.14.14.19;1.14.14.32;1.14.13.n7;1.14.14.-;1.14.14.14;1.14.14.80;5.3.99.4", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004508 steroid 17-alpha-monooxygenase activity;GO:0106256 hydroperoxy icosatetraenoate dehydratase activity;GO:0101020 estrogen 16-alpha-hydroxylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005739 mitochondrion", "go_biological_process": "GO:0042572 retinol metabolic process;GO:0002933 lipid hydroxylation;GO:0008210 estrogen metabolic process;GO:0042359 vitamin D metabolic process;GO:0001676 long-chain fatty acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MM10-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MJ10-1", "uniprot_id": "F1MJ10_BOVIN", "mass": 148903.0, "length": 1321, "protein_name": "E3 ubiquitin-protein ligase NEDD4", "gene_name": "NEDD4", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase NEDD4 isoform X1", "refseq_ac": "XP_010807618", "gene_names_uniprotkb": "NEDD4", "gene_names_refseq": "NEDD4", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase NEDD4; 2.3.2.26; HECT-type E3 ubiquitin transferase NEDD4", "protein_names_refseq": "E3 ubiquitin-protein ligase NEDD4 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:507781); (R-BTA-1169408); (R-BTA-1253288); (R-BTA-8948747); (R-BTA-8948751); (R-BTA-983168)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.27;2.3.2.23;2.3.2.31;2.3.2.26;3.1.3.67;3.1.3.16;3.1.3.48;2.3.2.-;2.3.2.34;2.3.2.25;2.3.2.24;2.7.10.1", "go_molecular_function": "GO:0019871 sodium channel inhibitor activity;GO:0061630 ubiquitin protein ligase activity;GO:0019870 potassium channel inhibitor activity;GO:0031698 beta-2 adrenergic receptor binding;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005654 nucleoplasm;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006955 immune response;GO:0007399 nervous system development;GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0023051 regulation of signaling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MJ10-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MIW7-1", "uniprot_id": "F1MIW7_BOVIN", "mass": 57453.0, "length": 513, "protein_name": "Activin receptor type-1-like", "gene_name": "ACVRL1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ACVRL1", "gene_names_refseq": "", "protein_names_uniprotkb": "Activin receptor type-1-like; 2.7.11.30; Serine/threonine-protein kinase receptor R3", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-201451)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.30", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004675 transmembrane receptor protein serine/threonine kinase activity;GO:0019901 protein kinase binding;GO:0005025 transforming growth factor beta receptor activity, type I", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0070724 BMP receptor complex", "go_biological_process": "GO:0001525 angiogenesis;GO:0007507 heart development;GO:0010629 negative regulation of gene expression;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MIW7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N1K8-1", "uniprot_id": "F1N1K8_BOVIN", "mass": 180085.0, "length": 1625, "protein_name": "Low-density lipoprotein receptor-related protein", "gene_name": "LRP5", "organism": "Bovine", "refseq_name": "low-density lipoprotein receptor-related protein 5 isoform X1", "refseq_ac": "XP_024843351", "gene_names_uniprotkb": "LRP5", "gene_names_refseq": "LRP5", "protein_names_uniprotkb": "Low-density lipoprotein receptor-related protein", "protein_names_refseq": "low-density lipoprotein receptor-related protein 5 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:534450); (R-BTA-3772470); (R-BTA-4641262); (R-BTA-4641263)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017147 Wnt-protein binding;GO:0042813 Wnt receptor activity;GO:0015026 coreceptor activity", "go_cellular_component": "GO:0016020 membrane;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0006897 endocytosis;GO:0008284 positive regulation of cell population proliferation;GO:0045597 positive regulation of cell differentiation;GO:0009887 animal organ morphogenesis;GO:0044281 small molecule metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N1K8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N759-1", "uniprot_id": "F1N759_BOVIN", "mass": 125187.0, "length": 1117, "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "organism": "Bovine", "refseq_name": "platelet-derived growth factor receptor beta isoform X2", "refseq_ac": "XP_010805769", "gene_names_uniprotkb": "PDGFRB", "gene_names_refseq": "PDGFRB", "protein_names_uniprotkb": "Platelet-derived growth factor receptor beta; 2.7.10.1; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; PDGF-R-beta; PDGFR-beta", "protein_names_refseq": "platelet-derived growth factor receptor beta isoform X2", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1257604); (R-BTA-186763); (R-BTA-186797); (R-BTA-5673001); (R-BTA-6811558)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;3.6.5.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;3.1.3.48;2.7.11.1;2.7.1.153;2.7.1.137;2.7.10.4;2.7.11.17;2.3.2.27", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0005019 platelet-derived growth factor beta-receptor activity;GO:0005161 platelet-derived growth factor receptor binding;GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle;GO:0043202 lysosomal lumen;GO:0043235 receptor complex", "go_biological_process": "GO:0006935 chemotaxis;GO:0008284 positive regulation of cell population proliferation;GO:0016477 cell migration;GO:1902533 positive regulation of intracellular signal transduction;GO:0001525 angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N759-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A4FV54-1", "uniprot_id": "RAB8A_BOVIN", "mass": 23684.0, "length": 207, "protein_name": "Ras-related protein Rab-8A", "gene_name": "RAB8A", "organism": "Bovine", "refseq_name": "ras-related protein Rab-8A", "refseq_ac": "NP_001098951", "gene_names_uniprotkb": "RAB8A", "gene_names_refseq": "RAB8A", "protein_names_uniprotkb": "Ras-related protein Rab-8A; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-8A", "tax_id": 9913, "disease": "", "pathway": " (bta:100125881); (R-BTA-2565942); (R-BTA-5620912); (R-BTA-5620916); (R-BTA-8854214); (R-BTA-8873719); (R-BTA-8876198)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "20631154", "class_list": "", "function": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB8A is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Regulates the compacted morphology of the Golgi. Together with MYO5B and RAB11A participates in epithelial cell polarization. Also involved in membrane trafficking to the cilium and ciliogenesis (By similarity). Together with MICALL2, may also regulate adherens junction assembly (By similarity). May play a role in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore play a role in glucose homeostasis (By similarity). Involved in autophagy. Participates in the export of a subset of neosynthesized proteins through a Rab8-Rab10-Rab11-dependent endososomal export route. Targeted to and stabilized on stressed lysosomes through LRRK2 phosphorylation. Suppresses stress-induced lysosomal enlargement through EHBP1 and EHNP1L1 effector proteins (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;2.7.11.1;3.6.5.-;3.6.5.3;2.7.11.21;3.6.1.5;2.7.11.11;2.7.11.26;2.7.11.22;2.7.11.23;3.6.1.15;3.6.5.4;2.5.1.60;3.6.4.10", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0031267 small GTPase binding;GO:0019003 GDP binding", "go_cellular_component": "GO:0005768 endosome;GO:0005794 Golgi apparatus;GO:0005813 centrosome;GO:0005886 plasma membrane;GO:0005929 cilium", "go_biological_process": "GO:0098969 neurotransmitter receptor transport to postsynaptic membrane;GO:0007409 axonogenesis;GO:0010506 regulation of autophagy;GO:0032869 cellular response to insulin stimulus;GO:0072659 protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A4FV54-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSM3-1", "uniprot_id": "F1MSM3_BOVIN", "mass": 269832.0, "length": 2533, "protein_name": "Neurogenic locus notch homolog protein 1", "gene_name": "NOTCH1", "organism": "Bovine", "refseq_name": "neurogenic locus notch homolog protein 1 isoform X1", "refseq_ac": "XP_024855411", "gene_names_uniprotkb": "NOTCH1", "gene_names_refseq": "NOTCH1", "protein_names_uniprotkb": "Neurogenic locus notch homolog protein 1", "protein_names_refseq": "neurogenic locus notch homolog protein 1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:767866)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0038023 signaling receptor activity;GO:0003713 transcription coactivator activity;GO:0004857 enzyme inhibitor activity;GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0031902 late endosome membrane;GO:0098978 glutamatergic synapse;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0001525 angiogenesis;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSM3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6QR55-1", "uniprot_id": "UBP4_BOVIN", "mass": 108510.0, "length": 963, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "organism": "Bovine", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 4", "refseq_ac": "NP_001093789", "gene_names_uniprotkb": "USP4", "gene_names_refseq": "USP4", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 4; 3.4.19.12; Deubiquitinating enzyme 4; Ubiquitin thioesterase 4; Ubiquitin-specific-processing protease 4", "protein_names_refseq": "deubiquitinating enzyme 4; ubiquitin carboxyl-terminal hydrolase 4; ubiquitin specific peptidase 4 (proto-oncogene); ubiquitin specific protease 4; ubiquitin thioesterase 4; ubiquitin thiolesterase 4; ubiquitin-specific-processing protease 4", "tax_id": 9913, "disease": "", "pathway": " (bta:508042); (R-BTA-5357786); (R-BTA-5357905); (R-BTA-5357956); (R-BTA-5689880)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB]; Deubiquitinating enzyme that removes conjugated ubiquitin from target proteins. Deubiquitinates PDPK1. Deubiquitinates TRIM21. Deubiquitinates receptor ADORA2A which increases the amount of functional receptor at the cell surface. Deubiquitinates HAS2. Deubiquitinates RHEB in response to EGF signaling, promoting mTORC1 signaling. May regulate mRNA splicing through deubiquitination of the U4 spliceosomal protein PRPF3. This may prevent its recognition by the U5 component PRPF8 thereby destabilizing interactions within the U4/U6.U5 snRNP. May also play a role in the regulation of quality control in the ER., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.27;3.4.19.12;2.7.11.25;2.3.2.31;2.7.11.10;2.7.11.1", "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0031685 adenosine receptor binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0000244 spliceosomal tri-snRNP complex assembly;GO:0031647 regulation of protein stability", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6QR55-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MF50-1", "uniprot_id": "F1MF50_BOVIN", "mass": 158301.0, "length": 1354, "protein_name": "Rho-associated protein kinase", "gene_name": "ROCK1", "organism": "Bovine", "refseq_name": "rho-associated protein kinase 1 isoform X1", "refseq_ac": "XP_002697835", "gene_names_uniprotkb": "ROCK1", "gene_names_refseq": "ROCK1", "protein_names_uniprotkb": "Rho-associated protein kinase", "protein_names_refseq": "rho-associated protein kinase 1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:785911); (R-BTA-111465); (R-BTA-3928662); (R-BTA-416482); (R-BTA-416572); (R-BTA-4420097); (R-BTA-5627117); (R-BTA-6798695); (R-BTA-8980692); (R-BTA-9013106); (R-BTA-9013407); (R-BTA-9013422); (R-BTA-9696264)", "pathway_count": 13, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein kinase which is a key regulator of actin cytoskeleton and cell polarity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0031267 small GTPase binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0030027 lamellipodium;GO:0005814 centriole;GO:0001726 ruffle", "go_biological_process": "GO:0006915 apoptotic process;GO:0007266 Rho protein signal transduction;GO:0010468 regulation of gene expression;GO:0010604 positive regulation of macromolecule metabolic process;GO:0071559 response to transforming growth factor beta", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MF50-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BGM0-1", "uniprot_id": "E1BGM0_BOVIN", "mass": 95964.0, "length": 843, "protein_name": "Transient receptor potential cation channel subfamily V member 1", "gene_name": "TRPV1", "organism": "Bovine", "refseq_name": "transient receptor potential cation channel subfamily V member 1 isoform X2", "refseq_ac": "XP_015314133", "gene_names_uniprotkb": "TRPV1", "gene_names_refseq": "TRPV1", "protein_names_uniprotkb": "Transient receptor potential cation channel subfamily V member 1; Osm-9-like TRP channel 1; Vanilloid receptor 1", "protein_names_refseq": "transient receptor potential cation channel subfamily V member 1 isoform X2", "tax_id": 9913, "disease": "", "pathway": " (bta:107131508); (R-BTA-3295583)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;1.8.-.-", "go_molecular_function": "GO:0005262 calcium channel activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051219 phosphoprotein binding", "go_cellular_component": "GO:0032591 dendritic spine membrane;GO:0098982 GABA-ergic synapse;GO:0005886 plasma membrane;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0034605 cellular response to heat;GO:0050965 detection of temperature stimulus involved in sensory perception of pain;GO:0071468 cellular response to acidic pH;GO:0098703 calcium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BGM0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MB25-1", "uniprot_id": "F1MB25_BOVIN", "mass": 58129.0, "length": 513, "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 1", "gene_name": "ENTPD1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ENTPD1", "gene_names_refseq": "", "protein_names_uniprotkb": "Ectonucleoside triphosphate diphosphohydrolase 1; 3.6.1.5; ATP diphosphohydrolase; Ecto-ATP diphosphohydrolase 1; Ecto-apyrase; Lymphoid cell activation antigen; Nucleoside triphosphate diphosphohydrolase 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-8850843)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates. This activity contributes to the regulation of extracellular levels of nucleotides. By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.5.5;3.6.4.6;3.6.4.10;3.6.1.6;5.6.2.3;3.6.5.-;3.6.5.3;3.6.1.64;3.6.1.62;5.6.2.-;2.7.4.3;3.6.4.-;3.6.1.16;3.6.1.53;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.6.5.4;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0005524 ATP binding;GO:0004382 GDP phosphatase activity;GO:0045134 UDP phosphatase activity;GO:0017111 ribonucleoside triphosphate phosphatase activity;GO:0004050 apyrase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005901 caveola;GO:0009897 external side of plasma membrane;GO:0005604 basement membrane", "go_biological_process": "GO:0009134 nucleoside diphosphate catabolic process;GO:0046032 ADP catabolic process;GO:0070527 platelet aggregation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MB25-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MII5-1", "uniprot_id": "F1MII5_BOVIN", "mass": 109923.0, "length": 984, "protein_name": "Ephrin type-B receptor 1", "gene_name": "EPHB1", "organism": "Bovine", "refseq_name": "ephrin type-B receptor 1 precursor", "refseq_ac": "NP_001179758", "gene_names_uniprotkb": "EPHB1", "gene_names_refseq": "EPHB1", "protein_names_uniprotkb": "Ephrin type-B receptor 1; 2.7.10.1", "protein_names_refseq": "ephrin type-B receptor 1 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:534731); (R-BTA-2682334); (R-BTA-3928662); (R-BTA-3928664); (R-BTA-3928665)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;2.7.11.1;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;3.4.24.24;3.4.24.35;3.6.4.-;3.6.5.2;2.7.10.4;3.4.23.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0005003 ephrin receptor activity;GO:0044877 protein-containing complex binding;GO:0005005 transmembrane-ephrin receptor activity;GO:0008046 axon guidance receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0031901 early endosome membrane;GO:0098978 glutamatergic synapse;GO:0030424 axon", "go_biological_process": "GO:0007155 cell adhesion;GO:0007399 nervous system development;GO:0016477 cell migration;GO:0001525 angiogenesis;GO:0048013 ephrin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MII5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MPG4-1", "uniprot_id": "F1MPG4_BOVIN", "mass": 43800.0, "length": 395, "protein_name": "F2R like trypsin receptor 1", "gene_name": "F2RL1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "F2RL1", "gene_names_refseq": "", "protein_names_uniprotkb": "F2R like trypsin receptor 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-375276); (R-BTA-416476)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015057 thrombin-activated receptor activity;GO:0031681 G-protein beta-subunit binding;GO:0002020 protease binding;GO:0004930 G protein-coupled receptor activity;GO:0001965 G-protein alpha-subunit binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005769 early endosome;GO:0031143 pseudopodium", "go_biological_process": "GO:0007596 blood coagulation;GO:0034141 positive regulation of toll-like receptor 3 signaling pathway;GO:0061028 establishment of endothelial barrier;GO:1900135 positive regulation of renin secretion into blood stream;GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MPG4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N5C8-1", "uniprot_id": "ENPP6_BOVIN", "mass": 50495.0, "length": 445, "protein_name": "Glycerophosphocholine choline phosphodiesterase ENPP6", "gene_name": "ENPP6", "organism": "Bovine", "refseq_name": "glycerophosphocholine choline phosphodiesterase ENPP6 isoform X2", "refseq_ac": "XP_005226063", "gene_names_uniprotkb": "ENPP6", "gene_names_refseq": "ENPP6", "protein_names_uniprotkb": "Glycerophosphocholine choline phosphodiesterase ENPP6; 3.1.4.-; 3.1.4.38; Choline-specific glycerophosphodiester phosphodiesterase; E-NPP 6; Ectonucleotide pyrophosphatase/phosphodiesterase family member 6; GPC-Cpde; NPP-6", "protein_names_refseq": "glycerophosphocholine choline phosphodiesterase ENPP6 isoform X2", "tax_id": 9913, "disease": "", "pathway": " (bta:537431); (R-BTA-6814848)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "19393038;23161088", "class_list": "", "function": "Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells (PubMed:23161088). Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 4, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 4, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 4, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.4.12;3.1.4.38;3.1.4.-;3.1.1.-;3.1.1.23;3.1.-.-", "go_molecular_function": "GO:0047390 glycerophosphocholine cholinephosphodiesterase activity;GO:0046872 metal ion binding;GO:0008889 glycerophosphodiester phosphodiesterase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane;GO:0005576 extracellular region", "go_biological_process": "GO:0019695 choline metabolic process;GO:0006629 lipid metabolic process;GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1N5C8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MX24-1", "uniprot_id": "F1MX24_BOVIN", "mass": 47614.0, "length": 440, "protein_name": "Battenin", "gene_name": "CLN3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CLN3", "gene_names_refseq": "", "protein_names_uniprotkb": "Battenin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-9845576)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0048306 calcium-dependent protein binding", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0012505 endomembrane system;GO:0016020 membrane;GO:0005773 vacuole;GO:0005769 early endosome", "go_biological_process": "GO:0006897 endocytosis;GO:0043066 negative regulation of apoptotic process;GO:0061024 membrane organization;GO:0007040 lysosome organization;GO:0030162 regulation of proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MX24-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BNE9-1", "uniprot_id": "KCNJ3_BOVIN", "mass": 56547.0, "length": 501, "protein_name": "G protein-activated inward rectifier potassium channel 1", "gene_name": "KCNJ3", "organism": "Bovine", "refseq_name": "G protein-activated inward rectifier potassium channel 1", "refseq_ac": "NP_001179553", "gene_names_uniprotkb": "KCNJ3; GIRK1", "gene_names_refseq": "GIRK-1; KCNJ3", "protein_names_uniprotkb": "G protein-activated inward rectifier potassium channel 1; GIRK-1; Inward rectifier K(+) channel Kir3.1; Potassium channel, inwardly rectifying subfamily J member 3", "protein_names_refseq": "G protein-activated inward rectifier potassium channel 1; inward rectifier K(+) channel Kir3.1; potassium channel, inwardly rectifying subfamily J member 3; potassium voltage-gated channel subfamily J member 3", "tax_id": 9913, "disease": "", "pathway": " (bta:526088); (R-BTA-1296041); (R-BTA-997272)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This potassium channel is controlled by G proteins. This receptor plays a crucial role in regulating the heartbeat., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.-.-", "go_molecular_function": "GO:0015467 G-protein activated inward rectifier potassium channel activity;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0042734 presynaptic membrane;GO:0098688 parallel fiber to Purkinje cell synapse;GO:1990566 I(KACh) inward rectifier potassium channel complex", "go_biological_process": "GO:1990573 potassium ion import across plasma membrane;GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E1BNE9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0JNH9-1", "uniprot_id": "APLF_BOVIN", "mass": 54326.0, "length": 485, "protein_name": "Aprataxin and PNK-like factor", "gene_name": "APLF", "organism": "Bovine", "refseq_name": "aprataxin and PNK-like factor", "refseq_ac": "NP_001071342", "gene_names_uniprotkb": "APLF", "gene_names_refseq": "APLF", "protein_names_uniprotkb": "Aprataxin and PNK-like factor; 3.1.1.-; Apurinic-apyrimidinic endonuclease APLF", "protein_names_refseq": "aprataxin and PNK-like factor; aprataxin- and PNK-like factor; apurinic-apyrimidinic endonuclease APLF", "tax_id": 9913, "disease": "", "pathway": " (bta:507989)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Histone chaperone involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with branched poly-ADP-ribose chains, a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions (By similarity). Following recruitment to DNA damage sites, acts as a histone chaperone that mediates histone eviction during DNA repair and promotes recruitment of histone variant MACROH2A1 (By similarity). Also has a nuclease activity: displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage (By similarity). Together with PARP3, promotes the retention of the LIG4-XRCC4 complex on chromatin and accelerate DNA ligation during non-homologous end-joining (NHEJ). Also acts as a negative regulator of cell pluripotency by promoting histone exchange. Required for the embryo implantation during the epithelial to mesenchymal transition in females (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0072572 poly-ADP-D-ribose binding;GO:0008270 zinc ion binding;GO:0000166 nucleotide binding;GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0004520 DNA endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0035861 site of double-strand break;GO:0090734 site of DNA damage;GO:0005654 nucleoplasm", "go_biological_process": "GO:0010717 regulation of epithelial to mesenchymal transition;GO:0006974 DNA damage response;GO:0006302 double-strand break repair;GO:0006303 double-strand break repair via nonhomologous end joining;GO:0000012 single strand break repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0JNH9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MQ96-1", "uniprot_id": "F1MQ96_BOVIN", "mass": 68300.0, "length": 596, "protein_name": "Protein kinase C", "gene_name": "PRKCI", "organism": "Bovine", "refseq_name": "protein kinase C iota type", "refseq_ac": "NP_001192884", "gene_names_uniprotkb": "PRKCI", "gene_names_refseq": "PRKCI", "protein_names_uniprotkb": "Protein kinase C; 2.7.11.13", "protein_names_refseq": "protein kinase C iota type", "tax_id": 9913, "disease": "", "pathway": " (bta:528478); (R-BTA-1912408); (R-BTA-209543); (R-BTA-420029); (R-BTA-9755511)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "20463008", "class_list": "", "function": "These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.3.2.27;2.7.11.10", "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0004697 diacylglycerol-dependent serine/threonine kinase activity;GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005903 brush border;GO:0016324 apical plasma membrane;GO:0043220 Schmidt-Lanterman incisure", "go_biological_process": "GO:0060252 positive regulation of glial cell proliferation;GO:0010976 positive regulation of neuron projection development;GO:0032869 cellular response to insulin stimulus;GO:0035556 intracellular signal transduction;GO:0072659 protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MQ96-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MAY3-1", "uniprot_id": "F1MAY3_BOVIN", "mass": 78395.0, "length": 707, "protein_name": "Solute carrier family 15 member 1", "gene_name": "SLC15A1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC15A1", "gene_names_refseq": "", "protein_names_uniprotkb": "Solute carrier family 15 member 1; Intestinal H(+)/peptide cotransporter; Oligopeptide transporter, small intestine isoform; Peptide transporter 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-427975)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Electrogenic proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports neutral and monovalently charged peptides with a proton to peptide stoichiometry of 1:1 or 2:1. Primarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen. Mediates transepithelial transport of muramyl and N-formylated bacterial dipeptides contributing to recognition of pathogenic bacteria by the mucosal immune system., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015293 symporter activity;GO:0035673 oligopeptide transmembrane transporter activity;GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity;GO:0015333 peptide:proton symporter activity;GO:0042937 tripeptide transmembrane transporter activity", "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0005903 brush border;GO:0005886 plasma membrane", "go_biological_process": "GO:0015031 protein transport;GO:0140206 dipeptide import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MAY3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MV74-1", "uniprot_id": "F1MV74_BOVIN", "mass": 58593.0, "length": 543, "protein_name": "Sterol carrier protein 2", "gene_name": "SCP2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SCP2", "gene_names_refseq": "", "protein_names_uniprotkb": "Sterol carrier protein 2; 2.3.1.155; 2.3.1.16; 2.3.1.176; Acetyl-CoA C-myristoyltransferase; Non-specific lipid-transfer protein; Propanoyl-CoA C-acyltransferase; SCP-2/3-oxoacyl-CoA thiolase; SCP-2/thiolase; SCP-chi; Sterol carrier protein X", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-193368); (R-BTA-2046106); (R-BTA-389887); (R-BTA-9033241)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mediates the transfer of all common phospholipids, cholesterol and gangliosides from the endoplasmic reticulum to the plasma membrane. May play a role in regulating steroidogenesis. Stimulates the microsomal conversion of 7-dehydrocholesterol to cholesterol. Also binds fatty acids and fatty acyl Coenzyme A (CoA) such as phytanoyl-CoA. Involved in the regulation phospholipid synthesis in endoplasmic reticulum enhancing the incorporation of exogenous fatty acid into glycerides. Seems to stimulate the rate-limiting step in phosphatidic acid formation mediated by GPAT3. Isoforms SCP2 and SCPx cooperate in peroxisomal oxidation of certain naturally occurring tetramethyl-branched fatty acyl-CoAs., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Plays a crucial role in the peroxisomal oxidation of branched-chain fatty acids. Catalyzes the last step of the peroxisomal beta-oxidation of branched chain fatty acids and the side chain of the bile acid intermediates di- and trihydroxycoprostanic acids (DHCA and THCA). Also active with medium and long straight chain 3-oxoacyl-CoAs. Stimulates the microsomal conversion of 7-dehydrocholesterol to cholesterol and transfers phosphatidylcholine and 7-dehydrocholesterol between membrances, in vitro. Isoforms SCP2 and SCPx cooperate in peroxisomal oxidation of certain naturally occurring tetramethyl-branched fatty acyl-CoAs., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.42;2.3.1.42;5.3.3.21;2.3.2.27;2.3.1.137;2.3.1.7;3.4.21.-;1.1.3.15;1.1.1.35;4.2.1.17;5.3.3.8;1.4.3.3;1.5.3.13;2.5.1.18;1.3.1.38;6.2.1.3;2.3.1.176;2.3.1.16;2.3.1.155;4.1.2.63;1.14.13.39;3.1.2.2;3.1.2.27;3.1.2.1;3.1.2.11;3.1.2.3;3.1.2.5;1.11.1.6;3.4.24.56;4.1.3.4;1.5.3.1;1.5.3.7;3.4.21.53;1.3.3.6;3.1.2.-;2.3.1.9", "go_molecular_function": "GO:0008289 lipid binding;GO:0003988 acetyl-CoA C-acyltransferase activity;GO:0050633 acetyl-CoA C-myristoyltransferase activity;GO:0070538 oleic acid binding;GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005777 peroxisome;GO:0005739 mitochondrion;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006869 lipid transport;GO:0032385 positive regulation of intracellular cholesterol transport;GO:1901373 lipid hydroperoxide transport;GO:0006633 fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MV74-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BMN2-1", "uniprot_id": "E1BMN2_BOVIN", "mass": 135236.0, "length": 1181, "protein_name": "Diaphanous related formin 3", "gene_name": "DIAPH3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DIAPH3", "gene_names_refseq": "", "protein_names_uniprotkb": "Diaphanous related formin 3", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-8980692); (R-BTA-9013106); (R-BTA-9013404); (R-BTA-9013406); (R-BTA-9013408); (R-BTA-9013423); (R-BTA-9035034)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0031267 small GTPase binding;GO:0008017 microtubule binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005884 actin filament;GO:0005815 microtubule organizing center", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0030041 actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BMN2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MIW3-1", "uniprot_id": "F1MIW3_BOVIN", "mass": 55545.0, "length": 489, "protein_name": "O-acyltransferase", "gene_name": "DGAT1", "organism": "Bovine", "refseq_name": "diacylglycerol O-acyltransferase 1", "refseq_ac": "NP_777118", "gene_names_uniprotkb": "DGAT1", "gene_names_refseq": "ARAT; DGAT1; DGAT", "protein_names_uniprotkb": "O-acyltransferase", "protein_names_refseq": "acyl-CoA retinol O-fatty-acyltransferase; diacylglycerol O-acyltransferase 1; diacylglycerol O-acyltransferase homolog 1; diglyceride acyltransferase 1; diglyceride acyltransferase; putative diacylglycerol acyltransferase 1; retinol O-fatty-acyltransferase", "tax_id": 9913, "disease": "", "pathway": " (bta:282609); (R-BTA-1482883); (R-BTA-6798695); (R-BTA-75109)", "pathway_count": 4, "publication_count": 8, "publication_id_list": "14983021;15190946;15342525;32482199;36981037;37268760;37641263;38395404", "class_list": "", "function": "Analysis of the impact of DGAT1 p.M435L and p.K232A variants on pre-mRNA splicing in a full-length gene assay. Publication Status: Online-Only, [RefSeq, PubMed]; Association of Single Nucleotide Polymorphism in the DGAT1 Gene with the Fatty Acid Composition of Cows Milked Once and Twice a Day. Publication Status: Online-Only, [RefSeq, PubMed]; Examined and characterized the occurrance of the K232A substitution in the DGAT1 gene in Bos taurus and Bos indicus, [RefSeq, PubMed]; Interaction of DGAT1 polymorphism, parity, and acetate supplementation on feeding behavior, milk synthesis, and plasma metabolites., [RefSeq, PubMed]; K allele, causing an increase in milk fat percentage in the live animal, is characterized by a higher Vmax in producing triglycerides than the A allele., [RefSeq, PubMed]; Role of diacylglycerol O-acyltransferase 1 (DGAT1) in lipolysis and autophagy of adipose tissue from ketotic dairy cows., [RefSeq, PubMed]; The functions and mechanisms of sequence differences of DGAT1 gene on milk fat synthesis between dairy cow and buffalo., [RefSeq, PubMed]; Variation in the number of tandem repeats of the 18mer element might be causal for the variability in the transcription level of the DGAT1 gene., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.1.23;3.1.1.79;2.3.1.-;2.3.1.20;3.1.1.4;3.1.1.3;2.3.1.22;2.3.1.76", "go_molecular_function": "GO:0004144 diacylglycerol O-acyltransferase activity;GO:0050252 retinol O-fatty-acyltransferase activity;GO:0042802 identical protein binding;GO:0003846 2-acylglycerol O-acyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0019432 triglyceride biosynthetic process;GO:0046339 diacylglycerol metabolic process;GO:0034379 very-low-density lipoprotein particle assembly;GO:0055089 fatty acid homeostasis;GO:0035336 long-chain fatty-acyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "F1MIW3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A7MBE0-1", "uniprot_id": "S22A1_BOVIN", "mass": 62502.0, "length": 563, "protein_name": "Solute carrier family 22 member 1", "gene_name": "SLC22A1", "organism": "Bovine", "refseq_name": "solute carrier family 22 member 1", "refseq_ac": "NP_001094568", "gene_names_uniprotkb": "SLC22A1; OCT1", "gene_names_refseq": "OCT1; SLC22A1", "protein_names_uniprotkb": "Solute carrier family 22 member 1; Organic cation transporter 1", "protein_names_refseq": "organic cation transporter 1; solute carrier family 22 member 1", "tax_id": 9913, "disease": "", "pathway": " (bta:519461); (R-BTA-112311); (R-BTA-181430); (R-BTA-2161517); (R-BTA-442660); (R-BTA-549127); (R-BTA-9793528)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "17892261", "class_list": "", "function": "Dopamine transport across the olfactory and respiratory mucosae is partially mediated by organic cation transporters, including OCT-1 and OCT-2., [RefSeq, PubMed]; Electrogenic voltage-dependent uniporter that mediates the transport of a variety of organic cations such as endogenous bioactive amines, cationic drugs and xenobiotics (By similarity). Functions as a pH- and Na(+)-independent, bidirectional transporter (By similarity). Cation cellular uptake or release is driven by the electrochemical potential (i.e. membrane potential and concentration gradient) and substrate selectivity (By similarity). Hydrophobicity is a major requirement for recognition in polyvalent substrates and inhibitors (By similarity). Primarily expressed in the basolateral membrane of hepatocytes and proximal tubules and involved in the uptake and disposition of cationic compounds from the blood by hepatic and renal clearance (By similarity). Most likely functions as an uptake carrier in enterocytes contributing to the intestinal elimination of organic cations from the systemic circulation. Transports endogenous monoamines such as N-1-methylnicotinamide (NMN), guanidine, neurotransmitters dopamine, serotonin, noradrenaline, adrenaline and histamine, and quaternary ammonium compound such as choline. Also transports natural polyamines such as spermidine, agmatine and putrescine at low affinity, but relatively high turnover. Involved in the hepatic and intestinal uptake of the vitamin B1/thiamine, hence regulating hepatic lipid and energy metabolism. Contributes to the influx and efflux of fatty acid carriers carnitines and acylcarnitines across the basolateral membrane of hepatocytes, from the liver to the systemic circulation and inversely and may be involved in regulating the systemic availability of hepatic acylcarnitines (By similarity). Also capable of transporting non-amine endogenous compounds such as prostaglandin E2 (PGE2) and prostaglandin F2-alpha (PGF2-alpha) (By similarity). May contribute to the transport of cationic compounds in testes across the blood-testis-barrier (By similarity). Also mediates the uptake of xenobiotics tributylmethylammonium (TBuMA), quinidine, N-methyl-quinine (NMQ), N-methyl-quinidine (NMQD) N-(4,4-azo-n-pentyl)-quinuclidine (APQ), azidoprocainamide methoiodide (AMP), N-(4,4-azo-n-pentyl)-21-deoxyajmalinium (APDA) and 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP) (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.-.-", "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0015651 quaternary ammonium group transmembrane transporter activity;GO:0042910 xenobiotic transmembrane transporter activity;GO:0022857 transmembrane transporter activity;GO:0008504 monoamine transmembrane transporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0016328 lateral plasma membrane;GO:0009925 basal plasma membrane;GO:0098793 presynapse", "go_biological_process": "GO:0015844 monoamine transport;GO:0015870 acetylcholine transport;GO:0015695 organic cation transport;GO:0006811 monoatomic ion transport;GO:0015872 dopamine transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A7MBE0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F6PSE2-1", "uniprot_id": "F6PSE2_BOVIN", "mass": 90648.0, "length": 803, "protein_name": "Nibrin", "gene_name": "NBN", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NBN", "gene_names_refseq": "", "protein_names_uniprotkb": "Nibrin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2559586); (R-BTA-5685938); (R-BTA-5685939); (R-BTA-5685942); (R-BTA-5693537); (R-BTA-5693548); (R-BTA-5693565); (R-BTA-5693568); (R-BTA-5693571); (R-BTA-5693579); (R-BTA-5693607); (R-BTA-5693616); (R-BTA-6804756); (R-BTA-69473)", "pathway_count": 14, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases. The complex (1) mediates the end resection of damaged DNA, which generates proper single-stranded DNA, a key initial steps in HR, and is (2) required for the recruitment of other repair factors and efficient activation of ATM and ATR upon DNA damage. The MRN complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11, to initiate end resection, which is required for single-strand invasion and recombination. Within the MRN complex, nbn acts as a protein-protein adapter, which specifically recognizes and binds phosphorylated proteins, promoting their recruitment to DNA damage sites. Recruits mre11 and rad50 components of the MRN complex to DSBs in response to DNA damage. Promotes the recruitment of PI3/PI4-kinase family members atm, atr, and probably DNA-PKcs to the DNA damage sites, activating their functions. Mediates the recruitment of phosphorylated rbbp8/CtIP to DSBs, leading to cooperation between the MRN complex and rbbp8/CtIP to initiate end resection., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003684 damaged DNA binding;GO:0042393 histone binding;GO:0043539 protein serine/threonine kinase activator activity;GO:0140031 phosphorylation-dependent protein binding;GO:0140463 chromatin-protein adaptor activity", "go_cellular_component": "GO:0030870 Mre11 complex;GO:0016605 PML body;GO:0000781 chromosome, telomeric region;GO:0005730 nucleolus;GO:0035861 site of double-strand break", "go_biological_process": "GO:0000723 telomere maintenance;GO:0006302 double-strand break repair;GO:0007095 mitotic G2 DNA damage checkpoint signaling;GO:0051321 meiotic cell cycle;GO:1990166 protein localization to site of double-strand break", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6PSE2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BPL8-1", "uniprot_id": "E1BPL8_BOVIN", "mass": 85899.0, "length": 750, "protein_name": "Neprilysin", "gene_name": "MME", "organism": "Bovine", "refseq_name": "neprilysin", "refseq_ac": "NP_001179813", "gene_names_uniprotkb": "MME", "gene_names_refseq": "MME", "protein_names_uniprotkb": "Neprilysin; 3.4.24.11; Atriopeptidase; Enkephalinase; Neutral endopeptidase 24.11; Skin fibroblast elastase", "protein_names_refseq": "neprilysin", "tax_id": 9913, "disease": "", "pathway": " (bta:536741); (R-BTA-2022377); (R-BTA-5578768); (R-BTA-6798695)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "19464387;27373199", "class_list": "", "function": "Hypoxia increased the expression of platelet-derived growth factor (PDGF) and transforming growth factor-beta1 (TGF-beta1) and decreased the expression of neprilysin (NEP), which contributed to the hypoxia-induced Endothelial-to-mesenchymal transition of pulmonary artery endothelial cells., [RefSeq, PubMed]; NEP expression is down-regulated in vascular endothelial cells by physiological laminar shear, possibly via a mechanotransduction mechanism involving NADPH oxidase-induced reactive oxygen species production.[Neprilysin], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.48;3.4.24.11;3.6.5.2;3.4.-.-;2.4.1.-;2.4.1.275;2.4.1.22;2.4.1.38;2.4.1.90;3.4.15.1;1.2.1.5;1.2.1.28;1.2.1.7;1.2.1.48", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0004181 metallocarboxypeptidase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005769 early endosome;GO:0005903 brush border", "go_biological_process": "GO:0006508 proteolysis;GO:0071493 cellular response to UV-B;GO:0007611 learning or memory;GO:0016485 protein processing;GO:0050435 amyloid-beta metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "E1BPL8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MB04-1", "uniprot_id": "F1MB04_BOVIN", "mass": 31408.0, "length": 277, "protein_name": "Caspase-3", "gene_name": "CASP3", "organism": "Bovine", "refseq_name": "caspase-3 isoform X1", "refseq_ac": "XP_010818547", "gene_names_uniprotkb": "CASP3", "gene_names_refseq": "CASP3", "protein_names_uniprotkb": "Caspase-3; 3.4.22.56", "protein_names_refseq": "caspase-3 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-111459); (R-BTA-111465); (R-BTA-111469); (R-BTA-140342); (R-BTA-2028269); (R-BTA-205025); (R-BTA-264870); (R-BTA-351906); (R-BTA-418889); (R-BTA-5620971); (R-BTA-9960519); (R-BTA-9960525)", "pathway_count": 12, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.22.36;2.5.1.58;2.5.1.59;3.4.22.56;2.7.11.1;2.7.11.13;2.3.2.27;3.4.22.62;2.7.10.2;3.4.22.-", "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity;GO:0008047 enzyme activator activity;GO:0004190 aspartic-type endopeptidase activity;GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005829 cytosol;GO:0014069 postsynaptic density", "go_biological_process": "GO:0006508 proteolysis;GO:0097194 execution phase of apoptosis;GO:0051604 protein maturation;GO:0016485 protein processing;GO:1902004 positive regulation of amyloid-beta formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MB04-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A2VDV2-1", "uniprot_id": "STK38_BOVIN", "mass": 54176.0, "length": 465, "protein_name": "Serine/threonine-protein kinase 38", "gene_name": "STK38", "organism": "Bovine", "refseq_name": "serine/threonine-protein kinase 38", "refseq_ac": "NP_001075071", "gene_names_uniprotkb": "STK38", "gene_names_refseq": "STK38", "protein_names_uniprotkb": "Serine/threonine-protein kinase 38; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase 38", "tax_id": 9913, "disease": "", "pathway": " (bta:533677); (R-BTA-9013418); (R-BTA-9013422)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Serine/threonine-protein kinase that acts as a negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2. Acts as an ufmylation 'reader' in a kinase-independent manner: specifically recognizes and binds mono-ufmylated histone H4 in response to DNA damage, promoting the recruitment of SUV39H1 to the double-strand breaks, resulting in ATM activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.3.2.27;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;3.6.4.-;3.1.4.-;3.1.4.35;2.7.11.-;2.7.11.4;3.6.1.-;5.6.1.7;2.7.2.3;3.6.4.13;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0106310 protein serine kinase activity;GO:0140566 histone reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0035861 site of double-strand break;GO:0005829 cytosol", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0006974 DNA damage response;GO:0043407 negative regulation of MAP kinase activity;GO:0000077 DNA damage checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A2VDV2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0JNC1-1", "uniprot_id": "CDS2_BOVIN", "mass": 51357.0, "length": 445, "protein_name": "Phosphatidate cytidylyltransferase 2", "gene_name": "CDS2", "organism": "Bovine", "refseq_name": "phosphatidate cytidylyltransferase 2", "refseq_ac": "NP_001071514", "gene_names_uniprotkb": "CDS2", "gene_names_refseq": "CDS2", "protein_names_uniprotkb": "Phosphatidate cytidylyltransferase 2; 2.7.7.41; CDP-DAG synthase 2; CDP-DG synthase 2; CDP-diacylglycerol synthase 2; CDP-diglyceride pyrophosphorylase 2; CDP-diglyceride synthase 2; CDS 2; CTP:phosphatidate cytidylyltransferase 2", "protein_names_refseq": "CDP-DAG synthase 2; CDP-DG synthase 2; CDP-DG synthetase 2; CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2; CDP-diglyceride pyrophosphorylase 2; CDP-diglyceride synthase 2; CDP-diglyceride synthetase 2; CDS 2; CTP:phosphatidate cytidylyltransferase 2; phosphatidate cytidylyltransferase 2", "tax_id": 9913, "disease": "", "pathway": " (bta:614834); (R-BTA-1483148)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.7.41", "go_molecular_function": "GO:0004605 phosphatidate cytidylyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0140042 lipid droplet formation;GO:0016024 CDP-diacylglycerol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0JNC1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BEM2-1", "uniprot_id": "E1BEM2_BOVIN", "mass": 56983.0, "length": 516, "protein_name": "phospholipase A2", "gene_name": "PLA2G3", "organism": "Bovine", "refseq_name": "group 3 secretory phospholipase A2 precursor", "refseq_ac": "NP_001074379", "gene_names_uniprotkb": "PLA2G3", "gene_names_refseq": "PLA2G3", "protein_names_uniprotkb": "phospholipase A2; 3.1.1.4", "protein_names_refseq": "GIII sPLA2; group 3 secretory phospholipase A2 precursor; group 3 secretory phospholipase A2; group III secretory phospholipase A2; phosphatidylcholine 2-acylhydrolase 3; phosphatidylcholine 2-acylhydrolase GIII; sPLA2-III", "tax_id": 9913, "disease": "", "pathway": " (bta:527631); (R-BTA-1482788); (R-BTA-1482839); (R-BTA-1482925)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.1.4", "go_molecular_function": "GO:0004623 phospholipase A2 activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0055037 recycling endosome;GO:0005814 centriole", "go_biological_process": "GO:0050482 arachidonate secretion;GO:0006644 phospholipid metabolic process;GO:0046473 phosphatidic acid metabolic process;GO:0010976 positive regulation of neuron projection development;GO:0043524 negative regulation of neuron apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BEM2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BPU0-1", "uniprot_id": "E1BPU0_BOVIN", "mass": 286147.0, "length": 2527, "protein_name": "Leucine-rich repeat serine/threonine-protein kinase 2", "gene_name": "LRRK2", "organism": "Bovine", "refseq_name": "leucine-rich repeat serine/threonine-protein kinase 2 isoform X1", "refseq_ac": "XP_010803364", "gene_names_uniprotkb": "LRRK2", "gene_names_refseq": "LRRK2", "protein_names_uniprotkb": "Leucine-rich repeat serine/threonine-protein kinase 2; 2.7.11.1", "protein_names_refseq": "leucine-rich repeat serine/threonine-protein kinase 2 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-8857538)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;3.6.5.5;2.7.10.1;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;3.6.5.-;3.6.5.3;2.7.1.153;2.7.1.137;2.7.1.154;3.6.1.5;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;3.6.1.15;2.7.11.-;2.7.11.4;3.6.5.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0000287 magnesium ion binding;GO:0003779 actin binding", "go_cellular_component": "GO:0005829 cytosol;GO:0098978 glutamatergic synapse;GO:0000139 Golgi membrane;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0009966 regulation of signal transduction;GO:0007154 cell communication;GO:1902902 negative regulation of autophagosome assembly;GO:0031344 regulation of cell projection organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BPU0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N206-1", "uniprot_id": "DLDH_BOVIN", "mass": 54187.0, "length": 509, "protein_name": "Dihydrolipoyl dehydrogenase, mitochondrial", "gene_name": "DLD", "organism": "Bovine", "refseq_name": "dihydrolipoyl dehydrogenase, mitochondrial", "refseq_ac": "NP_001193099", "gene_names_uniprotkb": "DLD", "gene_names_refseq": "DLD", "protein_names_uniprotkb": "Dihydrolipoyl dehydrogenase, mitochondrial; 1.8.1.4; Dihydrolipoamide dehydrogenase", "protein_names_refseq": "dihydrolipoyl dehydrogenase, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:533910); (R-BTA-204174); (R-BTA-5362517); (R-BTA-6783984); (R-BTA-70895); (R-BTA-9837999); (R-BTA-9853506); (R-BTA-9858328); (R-BTA-9859138); (R-BTA-9861559)", "pathway_count": 10, "publication_count": 3, "publication_id_list": "20097961;21168410;36854377", "class_list": "", "function": "Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched-chain amino acid-dehydrogenase complex). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A. In monomeric form may have additional moonlighting function as serine protease (By similarity). Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction (By similarity). The pyruvate dehydrogenase (PDH) complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links cytoplasmic glycolysis and the mitochondrial tricarboxylic acid (TCA) cycle. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and dihydrolipoamide dehydrogenase (E3). The E3 subunit catalyzes reoxidation of the dihydrolipoyl moiety on lipoyl-bearing domains (LBDs) of E2 with NAD+ as the ultimate electron acceptor (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Lipoamide dehydrogenase significantly accelerates the conversion of a defined subset of NO donors to NO., [RefSeq, PubMed]; Purification and identification of Bos taurus dihydrolipoyl dehydrogenase from heart mitochondria, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.35;5.3.3.21;2.7.11.-;2.3.1.61;2.3.1.37;1.2.4.1;5.3.3.8;2.3.1.41;3.6.4.10;1.8.1.4;1.2.4.4;3.5.3.1;5.6.1.7;3.1.3.43;7.1.2.2;2.3.1.168;2.3.1.-;7.1.1.2;1.2.1.3;4.2.1.3;4.98.1.1;1.1.1.30;1.1.1.42;1.3.8.5;1.2.4.2;2.3.3.1;2.3.1.9;3.4.21.92;2.7.11.1;2.7.11.4;3.1.3.16;3.1.3.52;1.1.1.37;6.2.1.-;6.2.1.4", "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0004148 dihydrolipoyl dehydrogenase (NADH) activity;GO:0000166 nucleotide binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0031514 motile cilium;GO:0043159 acrosomal matrix", "go_biological_process": "GO:0006103 2-oxoglutarate metabolic process;GO:0006086 pyruvate decarboxylation to acetyl-CoA;GO:0120551 2-oxoglutarate decarboxylation to succinyl-CoA;GO:0120552 branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA;GO:0019474 L-lysine catabolic process to acetyl-CoA", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1N206-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BCU9-1", "uniprot_id": "E1BCU9_BOVIN", "mass": 54108.0, "length": 486, "protein_name": "Serine/threonine-protein kinase STK11", "gene_name": "STK11", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "STK11", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein kinase STK11; 2.7.11.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-380972); (R-BTA-6804756)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Has a role in spermiogenesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0030295 protein kinase activator activity;GO:0000287 magnesium ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006915 apoptotic process;GO:0006974 DNA damage response;GO:0042593 glucose homeostasis;GO:0001558 regulation of cell growth;GO:0030010 establishment of cell polarity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BCU9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MS00-1", "uniprot_id": "F1MS00_BOVIN", "mass": 123980.0, "length": 1114, "protein_name": "Proto-oncogene tyrosine-protein kinase receptor Ret", "gene_name": "RET", "organism": "Bovine", "refseq_name": "proto-oncogene tyrosine-protein kinase receptor Ret isoform X1", "refseq_ac": "XP_024842420", "gene_names_uniprotkb": "RET", "gene_names_refseq": "RET", "protein_names_uniprotkb": "Proto-oncogene tyrosine-protein kinase receptor Ret; 2.7.10.1", "protein_names_refseq": "proto-oncogene tyrosine-protein kinase receptor Ret isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5673001); (R-BTA-8853659)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation in response to glia cell line-derived growth family factors (GDNF, NRTN, ARTN, PSPN and GDF15). In contrast to most receptor tyrosine kinases, RET requires not only its cognate ligands but also coreceptors, for activation. GDNF ligands (GDNF, NRTN, ARTN, PSPN and GDF15) first bind their corresponding GDNFR coreceptors (GFRA1, GFRA2, GFRA3, GFRA4 and GFRAL, respectively), triggering RET autophosphorylation and activation, leading to activation of downstream signaling pathways, including the MAPK- and AKT-signaling pathways. Acts as a dependence receptor via the GDNF-GFRA1 signaling: in the presence of the ligand GDNF in somatotrophs within pituitary, promotes survival and down regulates growth hormone (GH) production, but triggers apoptosis in absence of GDNF. Required for the molecular mechanisms orchestration during intestine organogenesis via the ARTN-GFRA3 signaling: involved in the development of enteric nervous system and renal organogenesis during embryonic life, and promotes the formation of Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. Mediates, through interaction with GDF15-receptor GFRAL, GDF15-induced cell-signaling in the brainstem which triggers an aversive response, characterized by nausea, vomiting, and/or loss of appetite in response to various stresses. Modulates cell adhesion via its cleavage by caspase in sympathetic neurons and mediates cell migration in an integrin (e.g. ITGB1 and ITGB3)-dependent manner. Also active in the absence of ligand, triggering apoptosis through a mechanism that requires receptor intracellular caspase cleavage. Triggers the differentiation of rapidly adapting (RA) mechanoreceptors. Involved in the development of the neural crest. Regulates nociceptor survival and size. Phosphorylates PTK2/FAK1., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;3.6.5.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.1;2.7.11.24;2.7.1.153;2.7.1.137;3.1.3.48;2.7.11.11;2.7.10.4;2.7.11.17", "go_molecular_function": "GO:0005524 ATP binding;GO:0005509 calcium ion binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0010008 endosome membrane;GO:0030424 axon;GO:0043235 receptor complex;GO:0098797 plasma membrane protein complex", "go_biological_process": "GO:0007399 nervous system development;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0010976 positive regulation of neuron projection development;GO:0030335 positive regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MS00-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BD36-1", "uniprot_id": "E1BD36_BOVIN", "mass": 106031.0, "length": 935, "protein_name": "Interleukin-6 receptor subunit beta", "gene_name": "IL6ST", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IL6ST", "gene_names_refseq": "", "protein_names_uniprotkb": "Interleukin-6 receptor subunit beta; Interleukin-6 signal transducer; Membrane glycoprotein 130; Oncostatin-M receptor subunit alpha", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:522155); (R-BTA-1059683); (R-BTA-110056); (R-BTA-6788467); (R-BTA-8984722); (R-BTA-9020956); (R-BTA-9958825)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004896 cytokine receptor activity;GO:0004915 interleukin-6 receptor activity;GO:0004921 interleukin-11 receptor activity;GO:0019970 interleukin-11 binding;GO:0019981 interleukin-6 binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0070110 ciliary neurotrophic factor receptor complex;GO:0005896 interleukin-6 receptor complex;GO:0005900 oncostatin-M receptor complex", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0043524 negative regulation of neuron apoptotic process;GO:0045747 positive regulation of Notch signaling pathway;GO:0045669 positive regulation of osteoblast differentiation;GO:0042102 positive regulation of T cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BD36-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BNR0-1", "uniprot_id": "E1BNR0_BOVIN", "mass": 515516.0, "length": 4567, "protein_name": "Apolipoprotein B", "gene_name": "APOB", "organism": "Bovine", "refseq_name": "apolipoprotein B-100", "refseq_ac": "XP_024855289", "gene_names_uniprotkb": "APOB", "gene_names_refseq": "APOB", "protein_names_uniprotkb": "Apolipoprotein B", "protein_names_refseq": "apolipoprotein B-100", "tax_id": 9913, "disease": "", "pathway": " (bta:494004); (R-BTA-202733); (R-BTA-3000471); (R-BTA-3000480); (R-BTA-3000497); (R-BTA-381426); (R-BTA-432142); (R-BTA-5686938); (R-BTA-8856825); (R-BTA-8856828); (R-BTA-8866423); (R-BTA-8957275); (R-BTA-8963888); (R-BTA-8963901); (R-BTA-8964026); (R-BTA-8964038); (R-BTA-9707616); (R-BTA-975634)", "pathway_count": 18, "publication_count": 2, "publication_id_list": "30573663;8315383", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005319 lipid transporter activity;GO:0008201 heparin binding;GO:0005543 phospholipid binding;GO:0050750 low-density lipoprotein particle receptor binding;GO:0035473 lipase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0034361 very-low-density lipoprotein particle;GO:0042627 chylomicron;GO:0034362 low-density lipoprotein particle", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0042953 lipoprotein transport;GO:0009615 response to virus;GO:0034374 low-density lipoprotein particle remodeling;GO:0042632 cholesterol homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "E1BNR0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BEL6-1", "uniprot_id": "E1BEL6_BOVIN", "mass": 104499.0, "length": 931, "protein_name": "Neuropilin", "gene_name": "NRP2", "organism": "Bovine", "refseq_name": "neuropilin-2 isoform X1", "refseq_ac": "XP_005202809", "gene_names_uniprotkb": "NRP2", "gene_names_refseq": "NRP2", "protein_names_uniprotkb": "Neuropilin", "protein_names_refseq": "neuropilin-2 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-194306)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0046872 metal ion binding;GO:0017154 semaphorin receptor activity;GO:0005021 vascular endothelial growth factor receptor activity", "go_cellular_component": "GO:0016020 membrane;GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0030424 axon;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0007411 axon guidance;GO:0097490 sympathetic neuron projection extension;GO:0097491 sympathetic neuron projection guidance;GO:0007507 heart development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BEL6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BH39-1", "uniprot_id": "E1BH39_BOVIN", "mass": 55921.0, "length": 491, "protein_name": "Katanin p60 ATPase-containing subunit A1", "gene_name": "KATNA1", "organism": "Bovine", "refseq_name": "katanin p60 ATPase-containing subunit A1", "refseq_ac": "NP_001179032", "gene_names_uniprotkb": "KATNA1", "gene_names_refseq": "KATNA1", "protein_names_uniprotkb": "Katanin p60 ATPase-containing subunit A1; 5.6.1.1; Katanin p60 subunit A1; p60 katanin", "protein_names_refseq": "katanin p60 (ATPase-containing) subunit A 1; katanin p60 ATPase-containing subunit A1", "tax_id": 9913, "disease": "", "pathway": " (bta:506715)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. 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2,3-bisphosphoglycerate 3-phosphatase; 3.1.3.62; 3.1.3.80", "protein_names_refseq": "multiple inositol polyphosphate histidine phosphatase, 1; multiple inositol polyphosphate phosphatase 1 isoform 1 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:541067); (R-BTA-1855231)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.67;3.1.3.16;3.1.3.48;3.1.3.62;3.1.3.80", "go_molecular_function": "GO:0034417 bisphosphoglycerate 3-phosphatase activity;GO:0052745 inositol phosphate phosphatase activity;GO:0003993 acid phosphatase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane;GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N1D8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F6Q9Q9-1", "uniprot_id": "F6Q9Q9_BOVIN", "mass": 63352.0, "length": 565, "protein_name": "Protein disulfide-isomerase", "gene_name": "P4HB", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "P4HB", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein disulfide-isomerase; 5.3.4.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1650814); (R-BTA-264876); (R-BTA-3299685); (R-BTA-381426); (R-BTA-5358346); (R-BTA-8866423); (R-BTA-8957275); (R-BTA-8963888); (R-BTA-8964041); (R-BTA-9020591); (R-BTA-9020933)", "pathway_count": 11, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.21.69;1.8.3.2;5.3.4.1;1.11.1.27;1.16.3.1;1.11.1.9;1.16.3.4;3.2.1.51;3.1.1.4;3.1.1.3;2.4.1.145;3.4.24.81;3.4.21.-;3.6.4.-", "go_molecular_function": "GO:0003756 protein disulfide isomerase activity;GO:0003779 actin binding;GO:0005178 integrin binding;GO:0046982 protein heterodimerization activity;GO:0015035 protein-disulfide reductase activity", "go_cellular_component": "GO:0005788 endoplasmic reticulum lumen;GO:0005886 plasma membrane;GO:0042470 melanosome;GO:0034663 endoplasmic reticulum chaperone complex;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:2000406 positive regulation of T cell migration;GO:0071456 cellular response to hypoxia;GO:0046598 positive regulation of viral entry into host cell;GO:1900026 positive regulation of substrate adhesion-dependent cell spreading;GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6Q9Q9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N2W0-1", "uniprot_id": "F1N2W0_BOVIN", "mass": 35687.0, "length": 329, "protein_name": "Prostaglandin reductase 1", "gene_name": "PTGR1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PTGR1", "gene_names_refseq": "", "protein_names_uniprotkb": "Prostaglandin reductase 1; 1.3.1.48; 1.3.1.74; 15-oxoprostaglandin 13-reductase; Dithiolethione-inducible gene 1 protein; Leukotriene B4 12-hydroxydehydrogenase; NAD(P)H-dependent alkenal/one oxidoreductase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.3.1.74;1.3.1.48", "go_molecular_function": "GO:0032440 2-alkenal reductase [NAD(P)H] activity;GO:0047522 15-oxoprostaglandin 13-reductase [NAD(P)+] activity;GO:0035798 2-alkenal reductase (NADPH) activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006693 prostaglandin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N2W0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O97827-1", "uniprot_id": "AGRL3_BOVIN", "mass": 176051.0, "length": 1580, "protein_name": "Adhesion G protein-coupled receptor L3", "gene_name": "ADGRL3", "organism": "Bovine", "refseq_name": "adhesion G protein-coupled receptor L3 precursor", "refseq_ac": "NP_851376", "gene_names_uniprotkb": "ADGRL3; LPH3; LPHN3", "gene_names_refseq": "ADGRL3; LEC3; LPHH3; LPHN3", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor L3; Latrophilin-3", "protein_names_refseq": "adhesion G protein-coupled receptor L3 precursor; latrophilin-3", "tax_id": 9913, "disease": "", "pathway": " (bta:282651)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "10025961", "class_list": "", "function": "Orphan adhesion G protein-coupled receptor (aGPCR), which mediates synapse specificity. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. Isoform 1 is specifically coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. Following G protein-coupled receptor activation, undergoes liquid-liquid phase transition, associates with (1) cell adhesion molecules that are expressed at the surface of adjacent cells, as well as (2) PDZ-containing proteins, such as SHANK3 and DLG4, in the cytoplasm to direct synapse formation., [UniProtKB, UniProtKB]; Orphan adhesion G-protein coupled receptor (aGPCR), which mediates synapse specificity. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. Isoform 1 is specifically coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. Following G-protein coupled receptor activation, undergoes liquid-liquid phase transition, associates with (1) cell adhesion molecules that are expressed at the surface of adjacent cells, as well as (2) PDZ-containing proteins, such as SHANK3 and DLG4, in the cytoplasm to direct synapse formation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 9, "predicted_n_glycosites": 9, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "O97818;O97819;O97820;O97821;O97822;O97823;O97824;O97825;O97826;O97828;O97829", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding;GO:0098631 cell adhesion mediator activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0030424 axon;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:1904861 excitatory synapse assembly;GO:0007165 signal transduction;GO:0007166 cell surface receptor signaling pathway;GO:0001764 neuron migration;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O97827-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A4FV52-1", "uniprot_id": "VGLU1_BOVIN", "mass": 61651.0, "length": 560, "protein_name": "Vesicular glutamate transporter 1", "gene_name": "SLC17A7", "organism": "Bovine", "refseq_name": "vesicular glutamate transporter 1", "refseq_ac": "NP_001091515", "gene_names_uniprotkb": "SLC17A7; VGLUT1", "gene_names_refseq": "SLC17A7", "protein_names_uniprotkb": "Vesicular glutamate transporter 1; Solute carrier family 17 member 7; VGluT1", "protein_names_refseq": "VGluT1; solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; vesicular glutamate transporter 1", "tax_id": 9913, "disease": "", "pathway": " (bta:518849); (R-BTA-210500); (R-BTA-442660)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Multifunctional transporter that transports L-glutamate as well as multiple ions such as chloride, proton, potassium, sodium and phosphate. At the synaptic vesicle membrane, mainly functions as an uniporter which transports preferentially L-glutamate but also phosphate from the cytoplasm into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. The L-glutamate or phosphate uniporter activity is electrogenic and is driven by the proton electrochemical gradient, mainly by the electrical gradient established by the vacuolar H(+)-ATPase across the synaptic vesicle membrane. In addition, functions as a chloride channel that allows a chloride permeation through the synaptic vesicle membrane that affects the proton electrochemical gradient and promotes synaptic vesicles acidification. Moreover, may function as a K(+)/H(+) antiport allowing to maintain the electrical gradient and to decrease chemical gradient and therefore sustain vesicular glutamate uptake. The vesicular K(+)/H(+) antiport activity is electroneutral. At the plasma membrane, following exocytosis, functions as a symporter of Na(+) and phosphate from the extracellular space to the cytoplasm allowing synaptic phosphate homeostasis regulation. The symporter activity is driven by an inside negative membrane potential and is electrogenic (By similarity). Is necessary for synaptic signaling of visual-evoked responses from photoreceptors (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.1.6;1.8.-.-;1.8.5.1", "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0015386 potassium:proton antiporter activity;GO:0005254 chloride channel activity;GO:0008068 extracellularly glutamate-gated chloride channel activity;GO:0005313 L-glutamate transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0048786 presynaptic active zone;GO:0098794 postsynapse;GO:0030672 synaptic vesicle membrane;GO:0034707 chloride channel complex", "go_biological_process": "GO:0050803 regulation of synapse structure or activity;GO:0035249 synaptic transmission, glutamatergic;GO:0006813 potassium ion transport;GO:0006821 chloride transport;GO:0055062 phosphate ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A4FV52-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O62830-1", "uniprot_id": "PPM1B_BOVIN", "mass": 53431.0, "length": 484, "protein_name": "Protein phosphatase 1B", "gene_name": "PPM1B", "organism": "Bovine", "refseq_name": "protein phosphatase 1B", "refseq_ac": "NP_776855", "gene_names_uniprotkb": "PPM1B", "gene_names_refseq": "PPM1B", "protein_names_uniprotkb": "Protein phosphatase 1B; 3.1.3.16; PP2C-beta; Protein phosphatase 2C isoform beta", "protein_names_refseq": "PP2C-beta; protein phosphatase 1B", "tax_id": 9913, "disease": "", "pathway": " (bta:281995); (R-BTA-1169408)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "9486768", "class_list": "", "function": "Enzyme with a broad specificity. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2T9W5", "ec_number_list": "3.1.3.16;3.1.3.48;3.1.3.67;2.3.2.31;2.3.2.23;3.1.3.74;3.1.3.52;3.1.3.53", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0030145 manganese ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0043124 negative regulation of canonical NF-kappaB signal transduction;GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction;GO:0006470 protein dephosphorylation;GO:0090263 positive regulation of canonical Wnt signaling pathway;GO:0043122 regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O62830-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BMF7-1", "uniprot_id": "UBP13_BOVIN", "mass": 97278.0, "length": 863, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 13", "gene_name": "USP13", "organism": "Bovine", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 13", "refseq_ac": "NP_001178195", "gene_names_uniprotkb": "USP13", "gene_names_refseq": "USP13", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 13; 3.4.19.12; Deubiquitinating enzyme 13; Ubiquitin thioesterase 13; Ubiquitin-specific-processing protease 13", "protein_names_refseq": "Deubiquitinating enzyme 13; Ubiquitin thioesterase 13; Ubiquitin-specific-processing protease 13; ubiquitin carboxyl-terminal hydrolase 13; ubiquitin specific peptidase 13 (isopeptidase T-3)", "tax_id": 9913, "disease": "", "pathway": " (bta:100141289); (R-BTA-5689880); (R-BTA-8948751)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy, endoplasmic reticulum-associated degradation (ERAD), cell cycle progression or DNA damage response. Component of a regulatory loop that controls autophagy and p53/TP53 levels: mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Alternatively, forms with NEDD4 a deubiquitination complex, which subsequently stabilizes VPS34 to promote autophagy. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability. In turn, PIK3C3/VPS34-containing complexes regulate USP13 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13. Recruited by nuclear UFD1 and mediates deubiquitination of SKP2, thereby regulating endoplasmic reticulum-associated degradation (ERAD). Also regulates ERAD through the deubiquitination of UBL4A a component of the BAG6/BAT3 complex. Mediates stabilization of SIAH2 independently of deubiquitinase activity: binds ubiquitinated SIAH2 and acts by impairing SIAH2 autoubiquitination. Regulates the cell cycle progression by stabilizing cell cycle proteins such as SKP2 and AURKB. In addition, plays an important role in maintaining genomic stability and in DNA replication checkpoint activation via regulation of RAP80 and TOPBP1. Deubiquitinates the multifunctional protein HMGB1 and subsequently drives its nucleocytoplasmic localization and its secretion. Positively regulates type I and type II interferon signalings by deubiquitinating STAT1 but negatively regulates antiviral response by deubiquitinating STING1., [UniProtKB, UniProtKB]; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.19.12;3.1.3.67;3.1.3.16;3.1.3.48;2.3.2.27", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0051087 protein-folding chaperone binding;GO:0031625 ubiquitin protein ligase binding;GO:1904288 BAT3 complex binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis;GO:0008283 cell population proliferation;GO:0010506 regulation of autophagy;GO:0070536 protein K63-linked deubiquitination;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E1BMF7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BKC4-1", "uniprot_id": "E1BKC4_BOVIN", "mass": 316227.0, "length": 2804, "protein_name": "Nipped-B protein", "gene_name": "NIPBL", "organism": "Bovine", "refseq_name": "nipped-B-like protein", "refseq_ac": "NP_001193513", "gene_names_uniprotkb": "NIPBL", "gene_names_refseq": "NIPBL", "protein_names_uniprotkb": "Nipped-B protein", "protein_names_refseq": "nipped-B-like protein", "tax_id": 9913, "disease": "", "pathway": " (bta:539566); (R-BTA-2470946)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an important role in the loading of the cohesin complex on to DNA. Forms a heterodimeric complex (also known as cohesin loading complex) with MAU2/SCC4 which mediates the loading of the cohesin complex onto chromatin. Plays a role in cohesin loading at sites of DNA damage. Its recruitment to double-strand breaks (DSBs) sites occurs in a CBX3-, RNF8- and RNF168-dependent manner whereas its recruitment to UV irradiation-induced DNA damage sites occurs in a ATM-, ATR-, RNF8- and RNF168-dependent manner. Along with ZNF609, promotes cortical neuron migration during brain development by regulating the transcription of crucial genes in this process. Preferentially binds promoters containing paused RNA polymerase II. Up-regulates the expression of SEMA3A, NRP1, PLXND1 and GABBR2 genes, among others., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0061775 cohesin loader activity;GO:0003682 chromatin binding;GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding;GO:0070087 chromo shadow domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:0032039 integrator complex;GO:0090694 Scc2-Scc4 cohesin loading complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0048638 regulation of developmental growth;GO:0010468 regulation of gene expression;GO:0048562 embryonic organ morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BKC4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MJN4-1", "uniprot_id": "F1MJN4_BOVIN", "mass": 57179.0, "length": 524, "protein_name": "Amino acid transporter", "gene_name": "SLC1A1", "organism": "Bovine", "refseq_name": "excitatory amino acid transporter 3", "refseq_ac": "NP_777024", "gene_names_uniprotkb": "SLC1A1", "gene_names_refseq": "SLC1A1", "protein_names_uniprotkb": "Amino acid transporter", "protein_names_refseq": "excitatory amino acid transporter 3; excitatory amino-acid carrier 1; renal high affinity glutamate transporter EAAC1; sodium-dependent glutamate/aspartate transporter 3; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1", "tax_id": 9913, "disease": "", "pathway": " (bta:282353); (R-BTA-210500); (R-BTA-9958863)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. Contributes to glutathione biosynthesis and protection against oxidative stress via its role in L-glutamate and L-cysteine transport. Negatively regulated by ARL6IP5., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0015293 symporter activity;GO:0042802 identical protein binding;GO:0005253 monoatomic anion channel activity;GO:0015108 chloride transmembrane transporter activity", "go_cellular_component": "GO:0045202 synapse;GO:0016324 apical plasma membrane;GO:0031902 late endosome membrane;GO:0031901 early endosome membrane;GO:0055038 recycling endosome membrane", "go_biological_process": "GO:0015813 L-glutamate transmembrane transport;GO:0006750 glutathione biosynthetic process;GO:0071577 zinc ion transmembrane transport;GO:0007613 memory;GO:0007626 locomotory behavior", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MJN4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BBZ8-1", "uniprot_id": "E1BBZ8_BOVIN", "mass": 35167.0, "length": 327, "protein_name": "FOS like 2, AP-1 transcription factor subunit", "gene_name": "FOSL2", "organism": "Bovine", "refseq_name": "fos-related antigen 2", "refseq_ac": "NP_001179879", "gene_names_uniprotkb": "FOSL2", "gene_names_refseq": "FOSL2", "protein_names_uniprotkb": "FOS like 2, AP-1 transcription factor subunit", "protein_names_refseq": "FOS-like antigen 2; fos-related antigen 2", "tax_id": 9913, "disease": "", "pathway": " (bta:509889)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32070024", "class_list": "", "function": "NCAPG Dynamically Coordinates the Myogenesis of Fetal Bovine Tissue by Adjusting Chromatin Accessibility. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0003690 double-stranded DNA binding;GO:0003682 chromatin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0035976 transcription factor AP-1 complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0032905 transforming growth factor beta1 production", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E1BBZ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A7Z056-1", "uniprot_id": "UBP20_BOVIN", "mass": 101815.0, "length": 912, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 20", "gene_name": "USP20", "organism": "Bovine", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 20", "refseq_ac": "NP_001098803", "gene_names_uniprotkb": "USP20", "gene_names_refseq": "USP20", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 20; 3.4.19.12; Deubiquitinating enzyme 20; Ubiquitin thioesterase 20; Ubiquitin-specific-processing protease 20", "protein_names_refseq": "deubiquitinating enzyme 20; ubiquitin carboxyl-terminal hydrolase 20; ubiquitin thioesterase 20; ubiquitin thiolesterase 20; ubiquitin-specific-processing protease 20", "tax_id": 9913, "disease": "", "pathway": " (bta:505839); (R-BTA-5689880)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Deubiquitinating enzyme that plays a role in many cellular processes including autophagy, cellular antiviral response or membrane protein biogenesis. Attenuates TLR4-mediated NF-kappa-B signaling by cooperating with beta-arrestin-2/ARRB2 and inhibiting TRAF6 autoubiquitination. Promotes cellular antiviral responses by deconjugating 'Lys-33' and 'Lys-48'-linked ubiquitination of STING1 leading to its stabilization. Plays an essential role in autophagy induction by regulating the ULK1 stability through deubiquitination of ULK1. Acts as a positive regulator for NF-kappa-B activation by TNF through deubiquitinating 'Lys-48'-linked polyubiquitination of SQSTM1, leading to its increased stability. Acts as a regulator of G protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Deubiquitinates MCL1, a pivotal member of the anti-apoptotic Bcl-2 protein family to regulate its stability. Within the endoplasmic reticulum, participates with USP33 in the rescue of post-translationally targeted membrane proteins that are inappropriately ubiquitinated by the cytosolic protein quality control in the cytosol., [UniProtKB, UniProtKB]; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.19.12", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001664 G protein-coupled receptor binding;GO:0004197 cysteine-type endopeptidase activity;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005813 centrosome;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006508 proteolysis;GO:0006897 endocytosis;GO:0007399 nervous system development;GO:0016579 protein deubiquitination;GO:0070536 protein K63-linked deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A7Z056-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A7E3S4-1", "uniprot_id": "RAF1_BOVIN", "mass": 72874.0, "length": 648, "protein_name": "RAF proto-oncogene serine/threonine-protein kinase", "gene_name": "RAF1", "organism": "Bovine", "refseq_name": "RAF proto-oncogene serine/threonine-protein kinase", "refseq_ac": "NP_001095975", "gene_names_uniprotkb": "RAF1", "gene_names_refseq": "C-RAF; RAF1", "protein_names_uniprotkb": "RAF proto-oncogene serine/threonine-protein kinase; 2.7.11.1; Proto-oncogene c-RAF; Raf-1; cRaf", "protein_names_refseq": "RAF proto-oncogene serine/threonine-protein kinase; proto-oncogene c-RAF", "tax_id": 9913, "disease": "", "pathway": " (bta:521196)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16305752;17329403", "class_list": "", "function": "Data suggest that G alpha(i3), Shc, Grb2, Ras, and Raf-1 link Src to activation of MAPK and to the AT(2)-dependent increase in eNOS expression in PAECs, [RefSeq, PubMed]; Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2). The phosphorylated form of RAF1 (on residues Ser-338 and Ser-339, by PAK1) phosphorylates BAD/Bcl2-antagonist of cell death at 'Ser-75'. Phosphorylates adenylyl cyclases: ADCY2, ADCY5 and ADCY6, resulting in their activation. Phosphorylates PPP1R12A resulting in inhibition of the phosphatase activity. Phosphorylates TNNT2/cardiac muscle troponin T. Can promote NF-kB activation and inhibit signal transducers involved in motility (ROCK2), apoptosis (MAP3K5/ASK1 and STK3/MST2), proliferation and angiogenesis (RB1). Can protect cells from apoptosis also by translocating to the mitochondria where it binds BCL2 and displaces BAD/Bcl2-antagonist of cell death. Regulates Rho signaling and migration, and is required for normal wound healing. Plays a role in the oncogenic transformation of epithelial cells via repression of the TJ protein, occludin (OCLN) by inducing the up-regulation of a transcriptional repressor SNAI2/SLUG, which induces down-regulation of OCLN. Restricts caspase activation in response to selected stimuli, notably Fas stimulation, pathogen-mediated macrophage apoptosis, and erythroid differentiation (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A7YY51", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:0007528 neuromuscular junction development;GO:0008285 negative regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0043410 positive regulation of MAPK cascade;GO:0042552 myelination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A7E3S4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A7Z063-1", "uniprot_id": "WASH1_BOVIN", "mass": 50773.0, "length": 471, "protein_name": "WASH complex subunit 1", "gene_name": "WASHC1", "organism": "Bovine", "refseq_name": "WASH complex subunit 1", "refseq_ac": "NP_001098876", "gene_names_uniprotkb": "WASHC1; WASH1", "gene_names_refseq": "WASH1; WASHC1", "protein_names_uniprotkb": "WASH complex subunit 1; WAS protein family homolog 1", "protein_names_refseq": "WAS protein family homolog 1; WASH complex subunit 1", "tax_id": 9913, "disease": "", "pathway": " (bta:533602)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "20498093", "class_list": "", "function": "Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Involved in endocytic trafficking of EGF. Involved in transferrin receptor recycling. Regulates the trafficking of endosomal alpha5beta1 integrin to the plasma membrane and involved in invasive cell migration. In T-cells involved in endosome-to-membrane recycling of receptors including T-cell receptor (TCR), CD28 and ITGAL; proposed to be implicated in T-cell proliferation and effector function. In dendritic cells involved in endosome-to-membrane recycling of major histocompatibility complex (MHC) class II probably involving retromer and subsequently allowing antigen sampling, loading and presentation during T-cell activation. Involved in negative regulation of autophagy independently from its role in endosomal sorting by inhibiting BECN1 ubiquitination to inactivate PIK3C3/Vps34 activity (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005829 cytosol;GO:0055037 recycling endosome;GO:0031901 early endosome membrane;GO:0055038 recycling endosome membrane", "go_biological_process": "GO:0015031 protein transport;GO:0016197 endosomal transport;GO:0034314 Arp2/3 complex-mediated actin nucleation;GO:0042147 retrograde transport, endosome to Golgi;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A7Z063-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BER5-1", "uniprot_id": "E1BER5_BOVIN", "mass": 109827.0, "length": 986, "protein_name": "receptor protein-tyrosine kinase", "gene_name": "EPHA4", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "EPHA4", "gene_names_refseq": "", "protein_names_uniprotkb": "receptor protein-tyrosine kinase; 2.7.10.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2682334); (R-BTA-3928663); (R-BTA-3928665)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.1;3.6.5.2;2.7.10.4", "go_molecular_function": "GO:0005524 ATP binding;GO:0005003 ephrin receptor activity;GO:0042802 identical protein binding;GO:0097161 DH domain binding;GO:0005005 transmembrane-ephrin receptor activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0030424 axon", "go_biological_process": "GO:0007155 cell adhesion;GO:0007399 nervous system development;GO:0050770 regulation of axonogenesis;GO:0007162 negative regulation of cell adhesion;GO:0008284 positive regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BER5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BCE6-1", "uniprot_id": "E1BCE6_BOVIN", "mass": 47609.0, "length": 454, "protein_name": "BCL3 transcription coactivator", "gene_name": "BCL3", "organism": "Bovine", "refseq_name": "B-cell lymphoma 3 protein", "refseq_ac": "NP_001192922", "gene_names_uniprotkb": "BCL3", "gene_names_refseq": "BCL3", "protein_names_uniprotkb": "BCL3 transcription coactivator", "protein_names_refseq": "B cell CLL/lymphoma 3; B-cell lymphoma 3 protein", "tax_id": 9913, "disease": "", "pathway": " (bta:531942)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003712 transcription coregulator activity;GO:0003713 transcription coactivator activity;GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0051707 response to other organism;GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BCE6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0AAA9STE8-1", "uniprot_id": "A0AAA9STE8_BOVIN", "mass": 32150.0, "length": 286, "protein_name": "Phospholipid phosphatase 1", "gene_name": "PLPP1", "organism": "Bovine", "refseq_name": "phospholipid phosphatase 1 isoform X1", "refseq_ac": "XP_024837173", "gene_names_uniprotkb": "PLPP1", "gene_names_refseq": "PLPP1; PPAP2A", "protein_names_uniprotkb": "Phospholipid phosphatase 1; 3.1.3.106; 3.1.3.4; 3.6.1.75; Lipid phosphate phosphohydrolase 1; PAP2-alpha; Phosphatidate phosphohydrolase type 2a; Phosphatidic acid phosphatase 2a", "protein_names_refseq": "phospholipid phosphatase 1 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.4;3.1.3.106;3.6.1.75;3.1.3.5;3.1.3.2;3.1.3.48;3.1.3.-;3.6.1.-;3.6.1.68", "go_molecular_function": "GO:0052642 lysophosphatidic acid phosphatase activity;GO:0008195 phosphatidate phosphatase activity;GO:0042392 sphingosine-1-phosphate phosphatase activity;GO:0106235 ceramide-1-phosphate phosphatase activity;GO:0000810 diacylglycerol diphosphate phosphatase activity", "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0005901 caveola", "go_biological_process": "GO:0006670 sphingosine metabolic process;GO:0007165 signal transduction;GO:0006672 ceramide metabolic process;GO:0006644 phospholipid metabolic process;GO:0046839 phospholipid dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AAA9STE8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLT0-1", "uniprot_id": "F1MLT0_BOVIN", "mass": 49289.0, "length": 431, "protein_name": "Bone morphogenetic protein 7", "gene_name": "BMP7", "organism": "Bovine", "refseq_name": "bone morphogenetic protein 7 precursor", "refseq_ac": "NP_001192944", "gene_names_uniprotkb": "BMP7", "gene_names_refseq": "BMP7", "protein_names_uniprotkb": "Bone morphogenetic protein 7; Osteogenic protein 1", "protein_names_refseq": "bone morphogenetic protein 7 (osteogenic protein 1); bone morphogenetic protein 7 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:540595); (R-BTA-2129379)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "19083154;23500594;23848497", "class_list": "", "function": "Data report that BMP-7 suppresses granulosa cell apoptosis by inhibiting the release of caspase-activated DNase (CAD) via a mechanism which does not appear to be associated with the mitochondrial pathway, whereas BMP-4 inhibits the release of CAD., [RefSeq, PubMed]; Some single nucleotide polymorphisms and haplotypes in BMP7 are associated with cattle growth traits., [RefSeq, PubMed]; The combined treatment with TGF-beta1 and BMP-7 or treatment first with TGF-beta1 followed by BMP-7 was more effective than other treatment groups in both chondrogenic differentiation and SZP secretion., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008083 growth factor activity;GO:0005125 cytokine activity;GO:0070700 BMP receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0030509 BMP signaling pathway;GO:0048468 cell development;GO:0009888 tissue development;GO:0051094 positive regulation of developmental process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1MLT0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BMX5-1", "uniprot_id": "E1BMX5_BOVIN", "mass": 103080.0, "length": 924, "protein_name": "Neuropilin", "gene_name": "NRP1", "organism": "Bovine", "refseq_name": "neuropilin-1 isoform X1", "refseq_ac": "XP_024856534", "gene_names_uniprotkb": "NRP1", "gene_names_refseq": "NRP1", "protein_names_uniprotkb": "Neuropilin", "protein_names_refseq": "neuropilin-1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-194306); (R-BTA-399954); (R-BTA-399955); (R-BTA-399956)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0046872 metal ion binding;GO:0017154 semaphorin receptor activity;GO:0005021 vascular endothelial growth factor receptor activity;GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0030424 axon", "go_biological_process": "GO:0001525 angiogenesis;GO:0030335 positive regulation of cell migration;GO:0007411 axon guidance;GO:0120035 regulation of plasma membrane bounded cell projection organization;GO:0001570 vasculogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BMX5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BIM8-1", "uniprot_id": "E1BIM8_BOVIN", "mass": 74614.0, "length": 688, "protein_name": "Tyrosine-protein kinase", "gene_name": "SRC", "organism": "Bovine", "refseq_name": "proto-oncogene tyrosine-protein kinase Src isoform X3", "refseq_ac": "XP_010809813", "gene_names_uniprotkb": "SRC", "gene_names_refseq": "SRC", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "proto-oncogene tyrosine-protein kinase Src isoform X3", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1227986); (R-BTA-1251985); (R-BTA-1253288); (R-BTA-1257604); (R-BTA-1295596); (R-BTA-1433557); (R-BTA-1433559); (R-BTA-177929); (R-BTA-180292); (R-BTA-186763); (R-BTA-191650); (R-BTA-210990); (R-BTA-354192); (R-BTA-354194); (R-BTA-372708); (R-BTA-389356); (R-BTA-389513); (R-BTA-3928663); (R-BTA-3928664); (R-BTA-3928665); (R-BTA-418592); (R-BTA-418594); (R-BTA-418885); (R-BTA-4420097); (R-BTA-456926); (R-BTA-5218921); (R-BTA-5607764); (R-BTA-5673000); (R-BTA-5674135); (R-BTA-6811558); (R-BTA-69231); (R-BTA-8853659); (R-BTA-8874081); (R-BTA-8934903); (R-BTA-8941858); (R-BTA-9009391); (R-BTA-9603381); (R-BTA-9766229); (R-BTA-9958810)", "pathway_count": 39, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Non-receptor protein tyrosine kinase which phosphorylates synaptophysin with high affinity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;3.6.5.2;2.7.11.1;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.39;2.3.2.27;2.7.11.24;2.7.11.22;2.7.1.153;2.7.1.137;3.1.3.48;3.6.4.-;3.6.5.-;3.1.3.16;2.7.10.4;2.7.11.17;3.6.4.10", "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0071253 connexin binding;GO:0004713 protein tyrosine kinase activity;GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005743 mitochondrial inner membrane;GO:0005829 cytosol;GO:0005884 actin filament;GO:0005886 plasma membrane", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:2000641 regulation of early endosome to late endosome transport;GO:2001286 regulation of caveolin-mediated endocytosis;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BIM8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A2VE79-1", "uniprot_id": "NUDT3_BOVIN", "mass": 19362.0, "length": 172, "protein_name": "Diphosphoinositol polyphosphate phosphohydrolase 1", "gene_name": "NUDT3", "organism": "Bovine", "refseq_name": "diphosphoinositol polyphosphate phosphohydrolase 1", "refseq_ac": "NP_001075935", "gene_names_uniprotkb": "NUDT3; DIPP1", "gene_names_refseq": "NUDT3", "protein_names_uniprotkb": "Diphosphoinositol polyphosphate phosphohydrolase 1; 3.6.1.10; 3.6.1.52; 3.6.1.59; 3.6.1.61; 3.6.1.62; Ap6A hydrolase; DIPP-1; Diadenosine hexaphosphate hydrolase; Endopolyphosphatase; Nucleoside diphosphate-linked moiety X motif 3; Nudix motif 3; m7GpppN-mRNA hydrolase; m7GpppX diphosphatase", "protein_names_refseq": "DIPP-1; ap6A hydrolase; diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1; diadenosine hexaphosphate hydrolase; diphosphoinositol polyphosphate phosphohydrolase 1; endopolyphosphatase; m7GpppN-mRNA hydrolase; m7GpppX diphosphatase; nucleoside diphosphate-linked moiety X motif 3; nudix (nucleoside diphosphate linked moiety X)-type motif 3; nudix motif 3", "tax_id": 9913, "disease": "", "pathway": " (bta:618855); (R-BTA-1855167)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction (By similarity). InsP6 (inositol hexakisphosphate) is not a substrate (By similarity). Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with diadenosine 5',5'''-P1,P6-hexaphosphate (Ap6A) and diadenosine 5',5'''- P1,P5-pentaphosphate (Ap5A) being the preferred substrates (By similarity). The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A (By similarity). Also able to hydrolyze 5- phosphoribose 1-diphosphate (By similarity). Acts as a decapping enzyme that can hydrolyze both monomethylated and unmethylated capped RNAs (By similarity). Hydrolyzes monomethylated capped RNA after both the alpha- and beta-phosphates generating m7GMP + ppRNA and m7GDP + pRNA (By similarity). Modulates the stability of a subset of mRNAs implicated in cell motility (By similarity). Divalent cations zinc, magnesium and manganese determine its substrate specificity (By similarity). Exhibits diphosphoinositol polyphosphate phosphohydrolase in the presence of magnesium ions, diadenosine hexaphosphate hydrolase activity in the presence of manganese ions and endopolyphosphatase activity in the presence of zinc ions (By similarity). Plays an important role in limiting DNA damage and maintaining cell survival upon oxidative stress via its endopolyphosphatase activity (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.1.62;3.6.1.64;3.6.1.59;3.6.1.52;3.6.1.10;3.6.1.61;3.1.4.1;3.6.1.9;3.6.1.-", "go_molecular_function": "GO:0000298 endopolyphosphatase activity;GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity;GO:0034431 bis(5'-adenosyl)-hexaphosphatase activity;GO:0034432 bis(5'-adenosyl)-pentaphosphatase activity;GO:0052840 inositol diphosphate tetrakisphosphate diphosphatase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0071543 diphosphoinositol polyphosphate metabolic process;GO:0071544 diphosphoinositol polyphosphate catabolic process;GO:1901907 diadenosine pentaphosphate catabolic process;GO:1901909 diadenosine hexaphosphate catabolic process;GO:1901911 adenosine 5'-(hexahydrogen pentaphosphate) catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A2VE79-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6BMK7-1", "uniprot_id": "NEUR1_BOVIN", "mass": 45433.0, "length": 415, "protein_name": "Sialidase-1", "gene_name": "NEU1", "organism": "Bovine", "refseq_name": "sialidase-1 precursor", "refseq_ac": "NP_001077111", "gene_names_uniprotkb": "NEU1", "gene_names_refseq": "NEU1", "protein_names_uniprotkb": "Sialidase-1; 3.2.1.18; Acetylneuraminyl hydrolase; Lysosomal sialidase; N-acetyl-alpha-neuraminidase 1; Neuraminidase-1", "protein_names_refseq": "N-acetyl-alpha-neuraminidase 1; acetylneuraminyl hydrolase; lysosomal sialidase; sialidase 1 (lysosomal sialidase); sialidase-1 precursor; sialidase-1", "tax_id": 9913, "disease": "", "pathway": " (bta:505554); (R-BTA-4085001); (R-BTA-6798695); (R-BTA-9840310)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "20163628", "class_list": "", "function": "Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage., [UniProtKB, UniProtKB]; Lysosomal exo-alpha-sialidase that catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage., [UniProtKB, UniProtKB]; NEU1 gene is not responsible for the lysosomal storage disease of Japanese Black cattle., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A4IFG6;Q5D0G1", "ec_number_list": "3.2.1.23;3.6.1.6;3.2.1.18;3.4.19.9;2.7.10.2;3.5.1.3;3.4.23.5;3.2.1.166;3.1.3.48;3.4.18.1;3.4.21.-;3.2.1.17;2.7.1.35;3.5.3.1;3.4.16.5;3.4.16.-", "go_molecular_function": "GO:0004308 exo-alpha-sialidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030054 cell junction;GO:0005764 lysosome", "go_biological_process": "GO:0006689 ganglioside catabolic process;GO:0009313 oligosaccharide catabolic process;GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A6BMK7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1B9U0-1", "uniprot_id": "E1B9U0_BOVIN", "mass": 22072.0, "length": 205, "protein_name": "Scleraxis bHLH transcription factor", "gene_name": "SCX", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SCX", "gene_names_refseq": "", "protein_names_uniprotkb": "Scleraxis bHLH transcription factor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:615157)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0046983 protein dimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005634 nucleus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1B9U0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BGA9-1", "uniprot_id": "E1BGA9_BOVIN", "mass": 101668.0, "length": 942, "protein_name": "Diacylglycerol kinase", "gene_name": "DGKQ", "organism": "Bovine", "refseq_name": "diacylglycerol kinase theta", "refseq_ac": "NP_001193234", "gene_names_uniprotkb": "DGKQ", "gene_names_refseq": "DGKQ", "protein_names_uniprotkb": "Diacylglycerol kinase; 2.7.1.107; DAG kinase", "protein_names_refseq": "diacylglycerol kinase theta; diacylglycerol kinase, theta 110kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:518371); (R-BTA-114508)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.1.107;2.7.1.93", "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0030971 receptor tyrosine kinase binding;GO:0030297 transmembrane receptor protein tyrosine kinase activator activity", "go_cellular_component": "GO:0016020 membrane;GO:0098978 glutamatergic synapse;GO:0005730 nucleolus;GO:0005768 endosome;GO:0005829 cytosol", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0046339 diacylglycerol metabolic process;GO:0046834 lipid phosphorylation;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BGA9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A2VDP1-1", "uniprot_id": "BRE1A_BOVIN", "mass": 113658.0, "length": 975, "protein_name": "E3 ubiquitin-protein ligase BRE1A", "gene_name": "RNF20", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase BRE1A", "refseq_ac": "NP_001075056", "gene_names_uniprotkb": "RNF20; BRE1A", "gene_names_refseq": "RNF20", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase BRE1A; 2.3.2.27; BRE1-A; RING finger protein 20; RING-type E3 ubiquitin transferase BRE1A", "protein_names_refseq": "BRE1-A; E3 ubiquitin-protein ligase BRE1A; RING-type E3 ubiquitin transferase BRE1A; ring finger protein 20, E3 ubiquitin protein ligase", "tax_id": 9913, "disease": "", "pathway": " (bta:513326); (R-BTA-8866654); (R-BTA-9013422)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator. Mediates the polyubiquitination of PA2G4 leading to its proteasome-mediated degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.39;2.3.2.27;2.7.11.1;3.1.4.-;3.1.4.35;3.6.1.-;5.6.1.7;2.3.2.23", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0031625 ubiquitin protein ligase binding;GO:0061630 ubiquitin protein ligase activity;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0000151 ubiquitin ligase complex;GO:0033503 HULC complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0030336 negative regulation of cell migration;GO:0045893 positive regulation of DNA-templated transcription;GO:0000209 protein polyubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A2VDP1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0JNB0-1", "uniprot_id": "FYN_BOVIN", "mass": 60718.0, "length": 537, "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "organism": "Bovine", "refseq_name": "tyrosine-protein kinase Fyn", "refseq_ac": "NP_001071440", "gene_names_uniprotkb": "FYN", "gene_names_refseq": "FYN", "protein_names_uniprotkb": "Tyrosine-protein kinase Fyn; 2.7.10.2; Proto-oncogene c-Fyn; p59-Fyn", "protein_names_refseq": "FYN oncogene related to SRC, FGR, YES; p59-Fyn; protein-tyrosine kinase fyn; proto-oncogene c-Fyn; proto-oncogene tyrosine-protein kinase Fyn; tyrosine-protein kinase Fyn", "tax_id": 9913, "disease": "", "pathway": " (bta:527263); (R-BTA-114604); (R-BTA-1227986); (R-BTA-1257604); (R-BTA-1433557); (R-BTA-1433559); (R-BTA-210990); (R-BTA-2424491); (R-BTA-373753); (R-BTA-375165); (R-BTA-389356); (R-BTA-389357); (R-BTA-389359); (R-BTA-389513); (R-BTA-3928663); (R-BTA-3928664); (R-BTA-3928665); (R-BTA-399954); (R-BTA-399955); (R-BTA-399956); (R-BTA-418885); (R-BTA-4420097); (R-BTA-5621480); (R-BTA-5673001); (R-BTA-6811558); (R-BTA-75892); (R-BTA-8866376); (R-BTA-912631); (R-BTA-9766229)", "pathway_count": 29, "publication_count": 3, "publication_id_list": "10930415;18710921;22403409", "class_list": "", "function": "Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance (PubMed:10930415). Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain (By similarity). Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions (By similarity). Involved in the regulation of cell adhesion and motility through phosphorylation of CTNNB1 (beta-catenin) and CTNND1 (delta-catenin) (By similarity). Regulates cytoskeletal remodeling by phosphorylating several proteins including the actin regulator WAS and the microtubule-associated proteins MAP2 and MAPT (By similarity). Promotes cell survival by phosphorylating AGAP2/PIKE-A and preventing its apoptotic cleavage (By similarity). Participates in signal transduction pathways that regulate the integrity of the glomerular slit diaphragm (an essential part of the glomerular filter of the kidney) by phosphorylating several slit diaphragm components including NPHS1, KIRREL1 and TRPC6 (By similarity). Plays a role in neural processes by phosphorylating DPYSL2, a multifunctional adapter protein within the central nervous system, ARHGAP32, a regulator for Rho family GTPases implicated in various neural functions, and SNCA, a small pre-synaptic protein (By similarity). Involved in reelin signaling by mediating phosphorylation of DAB1 following reelin (RELN)-binding to its receptor (By similarity). Participates in the downstream signaling pathways that lead to T-cell differentiation and proliferation following T-cell receptor (TCR) stimulation (By similarity). Phosphorylates PTK2B/PYK2 in response to T-cell receptor activation (By similarity). Also participates in negative feedback regulation of TCR signaling through phosphorylation of PAG1 and PDCD1 (By similarity). Phosphorylation of PAG1 promotes interaction between PAG1 and CSK and recruitment of CSK to lipid rafts (By similarity). Phosphorylation of PDCD1 leads to the recruitment of PTPN11/SHP-2 that mediates dephosphorylation of key TCR proximal signaling molecules (By similarity). CSK maintains LCK and FYN in an inactive form (By similarity). Promotes CD28-induced phosphorylation of VAV1 (By similarity). In mast cells, phosphorylates CLNK after activation of immunoglobulin epsilon receptor signaling (By similarity). Can also promote CD244-mediated NK cell activation (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB]; PECAM-1 and Fyn are essential components of a PECAM-1-based mechanosensory complex in endothelial cells., [RefSeq, PubMed]; The protein phosphatase PP2A/Balpha binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;3.6.5.2;2.7.11.1;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.24;2.7.11.26;2.3.2.27;2.7.1.153;2.7.1.137;3.1.3.48;2.7.11.11;3.1.3.16;2.7.10.4;2.7.11.17", "go_molecular_function": "GO:0004713 protein tyrosine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005102 signaling receptor binding;GO:0005524 ATP binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005768 endosome;GO:0005829 cytosol;GO:0005884 actin filament;GO:0005886 plasma membrane", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0010629 negative regulation of gene expression;GO:0018108 peptidyl-tyrosine phosphorylation;GO:0030154 cell differentiation;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0JNB0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G3N0C9-1", "uniprot_id": "G3N0C9_BOVIN", "mass": 49781.0, "length": 472, "protein_name": "E3 SUMO-protein ligase EGR2", "gene_name": "EGR2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "EGR2", "gene_names_refseq": "", "protein_names_uniprotkb": "E3 SUMO-protein ligase EGR2; E3 SUMO-protein transferase ERG2; Early growth response protein 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-9031628)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 transcriptional activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0061665 SUMO ligase activity;GO:0003682 chromatin binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0016925 protein sumoylation;GO:0045444 fat cell differentiation;GO:0035904 aorta development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3N0C9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N104-1", "uniprot_id": "F1N104_BOVIN", "mass": 91625.0, "length": 843, "protein_name": "Neuroligin 2", "gene_name": "NLGN2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NLGN2", "gene_names_refseq": "", "protein_names_uniprotkb": "Neuroligin 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-6794361)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042043 neurexin family protein binding;GO:0042802 identical protein binding;GO:0050839 cell adhesion molecule binding;GO:0008484 sulfuric ester hydrolase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0098982 GABA-ergic synapse;GO:0009986 cell surface;GO:0030424 axon", "go_biological_process": "GO:0007155 cell adhesion;GO:0007416 synapse assembly;GO:0097116 gephyrin clustering involved in postsynaptic density assembly;GO:0097104 postsynaptic membrane assembly;GO:0032024 positive regulation of insulin secretion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N104-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MD32-1", "uniprot_id": "F1MD32_BOVIN", "mass": 265025.0, "length": 2445, "protein_name": "histone acetyltransferase", "gene_name": "CREBBP", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CREBBP", "gene_names_refseq": "", "protein_names_uniprotkb": "histone acetyltransferase; 2.3.1.48", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1234158); (R-BTA-201722); (R-BTA-3134973); (R-BTA-3371568); (R-BTA-350054); (R-BTA-400206); (R-BTA-5621575); (R-BTA-8866907); (R-BTA-8939246); (R-BTA-8941856); (R-BTA-9018519); (R-BTA-933541); (R-BTA-9617629); (R-BTA-9707564); (R-BTA-9759194); (R-BTA-9841922); (R-BTA-9856649)", "pathway_count": 17, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "A0A8J8YPW6;M5FJS5", "ec_number_list": "2.3.1.48;2.1.1.319;2.7.11.22;2.7.11.23;2.3.1.286;3.5.1.98;3.6.4.10;2.7.11.1", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0004402 histone acetyltransferase activity;GO:0140297 DNA-binding transcription factor binding;GO:0003684 damaged DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000123 histone acetyltransferase complex;GO:0016604 nuclear body;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048511 rhythmic process;GO:2000819 regulation of nucleotide-excision repair;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MD32-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0AAA9TC29-1", "uniprot_id": "A0AAA9TC29_BOVIN", "mass": 57207.0, "length": 514, "protein_name": "Alanine--glyoxylate aminotransferase 2, mitochondrial", "gene_name": "AGXT2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AGXT2", "gene_names_refseq": "", "protein_names_uniprotkb": "Alanine--glyoxylate aminotransferase 2, mitochondrial; (R)-3-amino-2-methylpropionate--pyruvate transaminase; 2.6.1.18; 2.6.1.40; 2.6.1.44; Beta-ALAAT II; Beta-alanine-pyruvate aminotransferase; D-3-aminoisobutyrate-pyruvate aminotransferase; D-AIBAT; D-beta-aminoisobutyrate-pyruvate aminotransferase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Multifunctional aminotransferase with a broad substrate specificity. Catalyzes the conversion of glyoxylate to glycine using alanine as the amino donor. Catalyzes metabolism of not L- but the D-isomer of D-beta-aminoisobutyric acid to generate 2-methyl-3-oxopropanoate and alanine. Catalyzes the transfer of the amino group from beta-alanine to pyruvate to yield L-alanine and 3-oxopropanoate. Can metabolize NG-monomethyl-L-arginine (NMMA), asymmetric NG,NG-dimethyl-L-arginine (ADMA) and symmetric NG,N'G-dimethyl-L-arginine (SDMA). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.6.1.40;2.6.1.44;2.6.1.18", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0008453 alanine-glyoxylate transaminase activity;GO:0047305 (R)-3-amino-2-methylpropionate-pyruvate transaminase activity;GO:0016223 beta-alanine:pyruvate transaminase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0045429 positive regulation of nitric oxide biosynthetic process;GO:0009436 glyoxylate catabolic process;GO:0019265 glycine biosynthetic process, by transamination of glyoxylate;GO:0019481 L-alanine catabolic process, by transamination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0AAA9TC29-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MCY1-1", "uniprot_id": "F1MCY1_BOVIN", "mass": 163627.0, "length": 1552, "protein_name": "GLI family zinc finger 2", "gene_name": "GLI2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GLI2", "gene_names_refseq": "", "protein_names_uniprotkb": "GLI family zinc finger 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5610787); (R-BTA-5632684)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005813 centrosome;GO:0016020 membrane;GO:0016607 nuclear speck", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007224 smoothened signaling pathway;GO:0009653 anatomical structure morphogenesis;GO:0007389 pattern specification process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MCY1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A7E320-1", "uniprot_id": "UHRF1_BOVIN", "mass": 88339.0, "length": 786, "protein_name": "E3 ubiquitin-protein ligase UHRF1", "gene_name": "UHRF1", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase UHRF1", "refseq_ac": "NP_001096568", "gene_names_uniprotkb": "UHRF1", "gene_names_refseq": "UHRF1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase UHRF1; 2.3.2.27; Ubiquitin-like PHD and RING finger domain-containing protein 1; Ubiquitin-like-containing PHD and RING finger domains protein 1", "protein_names_refseq": "E3 ubiquitin-protein ligase UHRF1; RING-type E3 ubiquitin transferase UHRF1; ubiquitin-like PHD and RING finger domain-containing protein 1; ubiquitin-like, containing PHD and RING finger domains, 1; ubiquitin-like-containing PHD and RING finger domains protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:530411)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "19393038;26495903;32614952", "class_list": "", "function": "Developmental and hormonal regulation of ubiquitin-like with plant homeodomain and really interesting new gene finger domains 1 gene expression in ovarian granulosa and theca cells of cattle., [RefSeq, PubMed]; E3 ubiquitin-protein ligase that acts as a key epigenetic regulator by bridging DNA methylation and chromatin modification. Plays a key role in DNA methylation inheritance by promoting recruitment of DNMT1 to hemimethylated DNA and ensure faithful propagation of the DNA methylation patterns through DNA replication. Acts both as a histone reader and writer: specifically recognizes and binds (1) hemimethylated DNA at replication forks and (2) histone H3 trimethylated at 'Lys-9' and unmethylated at 'Arg-2' (H3K9me3 and H3R2me0, respectively), thereby activating its E3 ubiquitin-protein ligase activity. UHRF1 then mediates histone H3 'Lys-18' monoubiquitination (H3K18ub), a docking site for DNMT1, leading to DNMT1 recruitment and replication-coupled DNA methylation maintenance. Also mediates histone H3 'Lys-14' and 'Lys-23' ubiquitination (H3K14ub and H3K23ub) at lower level. Histone ubiquitin ligase activity also stimulates the methyltransferase activity of SUV39H1 and/or SUV39H2, promoting accumulation of H3K9me3 histone mark to reinformce heterochromatin state. Enriched in pericentric heterochromatin where it recruits different chromatin modifiers required for this chromatin replication. Also localizes to euchromatic regions where it negatively regulates transcription possibly by impacting DNA methylation and histone modifications. Plays a role in DNA repair by cooperating with UHRF2 to ensure recruitment of FANCD2 to interstrand cross-links (ICLs) leading to FANCD2 activation. Also ubiquitinates non-histone proteins, such as histone H3, KIF11 and PML. Acts as a critical player of proper spindle architecture by catalyzing the 'Lys-63'-linked ubiquitination of KIF11, thereby controlling KIF11 localization on the spindle., [UniProtKB, UniProtKB]; Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1MY11", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0042393 histone binding;GO:0004842 ubiquitin-protein transferase activity;GO:0044729 hemi-methylated DNA-binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0000791 euchromatin;GO:0005657 replication fork;GO:0000792 heterochromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A7E320-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A2VDZ4-1", "uniprot_id": "PLK4_BOVIN", "mass": 100707.0, "length": 893, "protein_name": "Serine/threonine-protein kinase PLK4", "gene_name": "PLK4", "organism": "Bovine", "refseq_name": "serine/threonine-protein kinase PLK4", "refseq_ac": "NP_001076896", "gene_names_uniprotkb": "PLK4; SAK", "gene_names_refseq": "PLK-4; PLK4", "protein_names_uniprotkb": "Serine/threonine-protein kinase PLK4; 2.7.11.21; PLK-4; Polo-like kinase 4; Serine/threonine-protein kinase Sak", "protein_names_refseq": "serine/threonine-protein kinase PLK4; serine/threonine-protein kinase Sak", "tax_id": 9913, "disease": "", "pathway": " (bta:514405); (R-BTA-2565942); (R-BTA-380259); (R-BTA-380270); (R-BTA-380284); (R-BTA-380320); (R-BTA-5620912); (R-BTA-8854518)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "26549124", "class_list": "", "function": "Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CPAP, CCP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Phosphorylates 'Ser-151' of FBXW5 during the G1/S transition, leading to inhibit FBXW5 ability to ubiquitinate SASS6. Its central role in centriole replication suggests a possible role in tumorigenesis, centrosome aberrations being frequently observed in tumors. Also involved in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles. Also involved in trophoblast differentiation by phosphorylating HAND1, leading to disrupt the interaction between HAND1 and MDFIC and activate HAND1. Phosphorylates CDC25C and CHEK2. Required for the recruitment of STIL to the centriole and for STIL-mediated centriole amplification (By similarity). Phosphorylates CEP131 and PCM1 which is essential for proper organization and integrity of centriolar satellites (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; These results indicated that PLK4 plays crucial roles in bovine oocyte meiotic maturation and subsequent early embryo development., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;3.6.5.2;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;3.6.5.-;2.7.11.-;2.7.11.4;2.7.2.3;3.6.4.10;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005813 centrosome;GO:0032154 cleavage furrow;GO:0005814 centriole", "go_biological_process": "GO:0046601 positive regulation of centriole replication;GO:0006468 protein phosphorylation;GO:0060271 cilium assembly;GO:0060707 trophoblast giant cell differentiation;GO:0007099 centriole replication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A2VDZ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O41515-1", "uniprot_id": "MLP3B_BOVIN", "mass": 14704.0, "length": 125, "protein_name": "Microtubule-associated protein 1 light chain 3 beta", "gene_name": "MAP1LC3B", "organism": "Bovine", "refseq_name": "microtubule-associated protein 1 light chain 3 beta", "refseq_ac": "NP_001001169", "gene_names_uniprotkb": "MAP1LC3B; MAP1ALC3; MAP1LC3", "gene_names_refseq": "MAP1LC3B", "protein_names_uniprotkb": "Microtubule-associated protein 1 light chain 3 beta; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3-like protein 2; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; Microtubule-associated proteins 1A/1B light chain 3B", "protein_names_refseq": "MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 B; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; autophagy-related protein LC3 B; autophagy-related ubiquitin-like modifier LC3 B; microtubule-associated protein 1 light chain 3 beta; microtubule-associated proteins 1A/1B light chain 3B", "tax_id": 9913, "disease": "", "pathway": " (bta:408001); (R-BTA-1632852); (R-BTA-5205685); (R-BTA-8854214); (R-BTA-8934903); (R-BTA-9664873); (R-BTA-9755511)", "pathway_count": 7, "publication_count": 4, "publication_id_list": "15140988;15325588;7908909;9557703", "class_list": "", "function": "Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. In response to cellular stress and upon mitochondria fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover. Upon nutrient stress, directly recruits cofactor JMY to the phagophore membrane surfaces and promotes JMY's actin nucleation activity and autophagosome biogenesis during autophagy., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6PZ01", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0031625 ubiquitin protein ligase binding;GO:0008429 phosphatidylethanolamine binding", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0031966 mitochondrial membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0000045 autophagosome assembly;GO:0009267 cellular response to starvation;GO:0000423 mitophagy;GO:0006995 cellular response to nitrogen starvation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "O41515-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A2VE31-1", "uniprot_id": "S38A2_BOVIN", "mass": 56214.0, "length": 506, "protein_name": "Sodium-coupled neutral amino acid symporter 2", "gene_name": "SLC38A2", "organism": "Bovine", "refseq_name": "sodium-coupled neutral amino acid symporter 2", "refseq_ac": "NP_001075893", "gene_names_uniprotkb": "SLC38A2; SNAT2", "gene_names_refseq": "SLC38A2", "protein_names_uniprotkb": "Sodium-coupled neutral amino acid symporter 2; Amino acid transporter A2; Protein 40-9-1; Solute carrier family 38 member 2; System A amino acid transporter 2; System A transporter 1; System N amino acid transporter 2", "protein_names_refseq": "amino acid transporter A2; protein 40-9-1; sodium-coupled neutral amino acid symporter 2; sodium-coupled neutral amino acid transporter 2; system A amino acid transporter 2; system A transporter 1; system N amino acid transporter 2", "tax_id": 9913, "disease": "", "pathway": " (bta:338044); (R-BTA-210500); (R-BTA-352230)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "41018975", "class_list": "", "function": "Symporter that cotransports neutral amino acids and sodium ions from the extracellular to the intracellular side of the cell membrane. The transport is pH-sensitive, Li(+)-intolerant, electrogenic, driven by the Na(+) electrochemical gradient and cotransports of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier (By similarity). May function in the transport of amino acids in the supply of maternal nutrients to the fetus through the placenta (By similarity). Maintains a key metabolic glutamine/glutamate balance underpinning retrograde signaling by dendritic release of the neurotransmitter glutamate (By similarity). Transports L-proline in differentiating osteoblasts for the efficient synthesis of proline-enriched proteins and provides proline essential for osteoblast differentiation and bone formation during bone development (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q95M41", "ec_number_list": "", "go_molecular_function": "GO:0005298 proline:sodium symporter activity;GO:0015171 amino acid transmembrane transporter activity;GO:0015175 neutral L-amino acid transmembrane transporter activity;GO:0015186 L-glutamine transmembrane transporter activity;GO:0005283 amino acid:sodium symporter activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0033120 positive regulation of RNA splicing;GO:0015824 proline transport;GO:0032328 alanine transport;GO:1904271 L-proline import across plasma membrane;GO:0006865 amino acid transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A2VE31-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MQB8-1", "uniprot_id": "F1MQB8_BOVIN", "mass": 79481.0, "length": 723, "protein_name": "protein acetyllysine N-acetyltransferase", "gene_name": "SIRT1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SIRT1", "gene_names_refseq": "", "protein_names_uniprotkb": "protein acetyllysine N-acetyltransferase; 2.3.1.286", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3371453); (R-BTA-427359); (R-BTA-9617629); (R-BTA-9764725); (R-BTA-9841922); (R-BTA-9856649)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.-;2.3.1.48;2.3.1.286;3.5.1.98;3.6.4.10;2.7.11.1", "go_molecular_function": "GO:0046872 metal ion binding;GO:0016740 transferase activity;GO:0070403 NAD+ binding;GO:0004407 histone deacetylase activity;GO:1990254 keratin filament binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0010824 regulation of centrosome duplication;GO:0070857 regulation of bile acid biosynthetic process;GO:0090400 stress-induced premature senescence;GO:0000720 pyrimidine dimer repair by nucleotide-excision repair;GO:1904179 positive regulation of adipose tissue development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MQB8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N079-1", "uniprot_id": "F1N079_BOVIN", "mass": 140374.0, "length": 1273, "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RTEL1", "gene_names_refseq": "", "protein_names_uniprotkb": "Regulator of telomere elongation helicase 1; 5.6.2.-", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-171319); (R-BTA-174430)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "A probable ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53;2.7.11.22", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0031965 nuclear membrane;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0090657 telomeric loop disassembly;GO:1904430 negative regulation of t-circle formation;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006260 DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N079-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O77750-1", "uniprot_id": "AQP4_BOVIN", "mass": 34672.0, "length": 323, "protein_name": "Aquaporin-4", "gene_name": "AQP4", "organism": "Bovine", "refseq_name": "aquaporin-4 isoform Ax", "refseq_ac": "NP_001304721", "gene_names_uniprotkb": "AQP4", "gene_names_refseq": "AQP-4; AQP4; MIWC; WCH4", "protein_names_uniprotkb": "Aquaporin-4; AQP-4; MIWC; Mercurial-insensitive water channel; WCH4", "protein_names_refseq": "aquaporin-4 isoform Ax; mercurial-insensitive water channel", "tax_id": 9913, "disease": "", "pathway": " (bta:281008); (R-BTA-432040); (R-BTA-432047)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "10673041", "class_list": "", "function": "Forms a water-specific channel. Plays an important role in brain water homeostasis and in glymphatic solute transport. Required for a normal rate of water exchange across the blood brain interface. Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways. Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP. Plays a redundant role in urinary water homeostasis and urinary concentrating ability., [UniProtKB, UniProtKB]; This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]., [RefSeq]", "predicted_glycosites": 4, "predicted_n_glycosites": 2, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q17QE1", "ec_number_list": "", "go_molecular_function": "GO:0015250 water channel activity;GO:0015267 channel activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0010008 endosome membrane;GO:0042383 sarcolemma", "go_biological_process": "GO:0051289 protein homotetramerization;GO:0009992 intracellular water homeostasis;GO:0006833 water transport;GO:0050891 multicellular organismal-level water homeostasis;GO:0090660 cerebrospinal fluid circulation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O77750-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MB67-1", "uniprot_id": "F1MB67_BOVIN", "mass": 74053.0, "length": 671, "protein_name": "Arachidonate--CoA ligase", "gene_name": "SLC27A1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC27A1", "gene_names_refseq": "", "protein_names_uniprotkb": "Arachidonate--CoA ligase; 6.2.1.15; 6.2.1.3; Long-chain-fatty-acid--CoA ligase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-804914)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.2.1.3;6.2.1.15;6.2.1.-;6.2.1.76", "go_molecular_function": "GO:0000166 nucleotide binding;GO:0004467 long-chain fatty acid-CoA ligase activity;GO:0047676 arachidonate-CoA ligase activity;GO:0005324 long-chain fatty acid transmembrane transporter activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0012505 endomembrane system;GO:0016020 membrane;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0009925 basal plasma membrane", "go_biological_process": "GO:0006869 lipid transport;GO:1990379 lipid transport across blood-brain barrier;GO:0001676 long-chain fatty acid metabolic process;GO:0044539 long-chain fatty acid import into cell;GO:0044381 glucose import in response to insulin stimulus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MB67-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A7Z064-1", "uniprot_id": "HMDH_BOVIN", "mass": 97727.0, "length": 888, "protein_name": "3-hydroxy-3-methylglutaryl-coenzyme A reductase", "gene_name": "HMGCR", "organism": "Bovine", "refseq_name": "3-hydroxy-3-methylglutaryl-coenzyme A reductase", "refseq_ac": "NP_001099083", "gene_names_uniprotkb": "HMGCR", "gene_names_refseq": "HMGCR; hmg-coa-r", "protein_names_uniprotkb": "3-hydroxy-3-methylglutaryl-coenzyme A reductase; 1.1.1.34; HMG-CoA reductase", "protein_names_refseq": "3-hydroxy-3-methylglutaryl-coenzyme A reductase; HMG-CoA reductase", "tax_id": 9913, "disease": "", "pathway": " (bta:407159); (R-BTA-9969896)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "19393038;33024216", "class_list": "", "function": "Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis., [UniProtKB, UniProtKB]; HMGR overexpression and interference affect the expression of steroidogenic genes and cholesterol content in bovine intramuscular adipocytes. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "F1MMP6", "ec_number_list": "1.1.1.34", "go_molecular_function": "GO:0120225 coenzyme A binding;GO:0030695 GTPase regulator activity;GO:0070402 NADPH binding;GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0098554 cytoplasmic side of endoplasmic reticulum membrane;GO:0005778 peroxisomal membrane;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0050709 negative regulation of protein secretion;GO:0016126 sterol biosynthetic process;GO:0015936 coenzyme A metabolic process;GO:0042177 negative regulation of protein catabolic process;GO:1900222 negative regulation of amyloid-beta clearance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A7Z064-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BPM4-1", "uniprot_id": "E1BPM4_BOVIN", "mass": 332131.0, "length": 2991, "protein_name": "ATP-dependent chromatin remodeler CHD7", "gene_name": "CHD7", "organism": "Bovine", "refseq_name": "chromodomain-helicase-DNA-binding protein 7 isoform X1", "refseq_ac": "XP_024857592", "gene_names_uniprotkb": "CHD7", "gene_names_refseq": "CHD7", "protein_names_uniprotkb": "ATP-dependent chromatin remodeler CHD7; Chromo domain-containing protein 7", "protein_names_refseq": "chromodomain-helicase-DNA-binding protein 7 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:533175); (R-BTA-9943962)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "ATP-dependent chromatin-remodeling factor, slides nucleosomes along DNA; nucleosome sliding requires ATP. Probable transcription regulator. May be involved in the in 45S precursor rRNA production., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0021545 cranial nerve development;GO:0043584 nose development;GO:0048806 genitalia development;GO:0060123 regulation of growth hormone secretion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BPM4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MQF6-1", "uniprot_id": "F1MQF6_BOVIN", "mass": 21951.0, "length": 195, "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PYCARD", "gene_names_refseq": "", "protein_names_uniprotkb": "Apoptosis-associated speck-like protein containing a CARD; PYD and CARD domain-containing protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5660668); (R-BTA-6798695); (R-BTA-844456)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0046983 protein dimerization activity;GO:0002020 protease binding;GO:0030674 protein-macromolecule adaptor activity;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0140738 NLRP6 inflammasome complex", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0006915 apoptotic process;GO:0032722 positive regulation of chemokine production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MQF6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1B726-1", "uniprot_id": "E1B726_BOVIN", "mass": 92940.0, "length": 826, "protein_name": "Plasminogen", "gene_name": "PLG", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PLG", "gene_names_refseq": "", "protein_names_uniprotkb": "Plasminogen; 3.4.21.7", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-114608); (R-BTA-1592389); (R-BTA-186797); (R-BTA-75205)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1, C4 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.21.7;3.4.24.7;3.4.24.17;2.3.2.13;3.4.21.73;1.8.3.5;3.4.21.68;3.4.21.34;3.4.21.46", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0004175 endopeptidase activity;GO:0005102 signaling receptor binding;GO:0019900 kinase binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005615 extracellular space;GO:0009986 cell surface;GO:0098685 Schaffer collateral - CA1 synapse", "go_biological_process": "GO:0006508 proteolysis;GO:0007596 blood coagulation;GO:0042730 fibrinolysis;GO:0048771 tissue remodeling;GO:0099183 trans-synaptic signaling by BDNF, modulating synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1B726-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BB52-1", "uniprot_id": "CDK13_BOVIN", "mass": 164717.0, "length": 1512, "protein_name": "Cyclin-dependent kinase 13", "gene_name": "CDK13", "organism": "Bovine", "refseq_name": "cyclin-dependent kinase 13 isoform 1", "refseq_ac": "NP_001192360", "gene_names_uniprotkb": "CDK13; CDC2L5; CDC2L", "gene_names_refseq": "CDC2L5; CDK13", "protein_names_uniprotkb": "Cyclin-dependent kinase 13; 2.7.11.22; 2.7.11.23; CDC2-related protein kinase 5; Cell division cycle 2-like protein kinase 5; Cell division protein kinase 13", "protein_names_refseq": "CDC2-related protein kinase 5; cell division cycle 2-like 5 (cholinesterase-related cell division controller); cell division cycle 2-like protein kinase 5; cell division protein kinase 13; cyclin-dependent kinase 13 isoform 1", "tax_id": 9913, "disease": "", "pathway": " (bta:511147); (R-BTA-6796648); (R-BTA-6798695)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 19, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.42;2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.5.1.18;2.7.11.23;2.7.12.1;2.7.1.1;2.7.12.2;2.7.11.17;2.7.11.39;3.2.1.23;2.7.10.2;2.4.2.1;2.7.1.150;5.2.1.8;4.1.2.13;3.6.1.6;2.7.11.12;2.7.11.31;2.3.2.27;2.7.11.26;2.7.11.21;3.1.6.14;2.7.1.153;2.7.1.137;2.7.1.154;3.6.4.13;1.1.1.205;2.7.1.11;2.3.2.26;4.1.1.32;2.4.1.25;3.2.1.33;2.7.11.38;4.2.99.18;5.6.2.4;3.6.4.12;3.4.23.5;1.13.11.34;1.13.11.12;3.6.4.6;1.16.3.1;1.11.1.6;2.7.11.11;3.4.18.1;3.4.22.1;3.6.4.10;3.4.22.27;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;3.4.24.35;3.6.5.-;3.1.1.47;5.3.2.1;5.3.3.12;3.4.19.1;2.4.1.1;3.5.1.23;3.5.1.-;3.4.22.52;2.7.11.-;2.7.11.4;2.3.3.8;5.4.2.11;5.4.2.4;3.3.2.6;3.4.11.4;3.4.21.46;2.7.2.3;4.1.2.4;5.3.1.9;5.1.3.-;3.6.1.-;4.2.1.24;2.7.11.10", "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0106310 protein serine kinase activity;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex;GO:0008024 cyclin/CDK positive transcription elongation factor complex;GO:0002945 cyclin K-CDK13 complex", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030097 hemopoiesis;GO:0032968 positive regulation of transcription elongation by RNA polymerase II;GO:0000380 alternative mRNA splicing, via spliceosome;GO:0009966 regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BB52-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0JNM1-1", "uniprot_id": "OSTB_BOVIN", "mass": 14599.0, "length": 130, "protein_name": "Organic solute transporter subunit beta", "gene_name": "SLC51B", "organism": "Bovine", "refseq_name": "organic solute transporter subunit beta", "refseq_ac": "NP_001071335", "gene_names_uniprotkb": "SLC51B; OSTB", "gene_names_refseq": "OSTBETA; OSTB; SLC51B", "protein_names_uniprotkb": "Organic solute transporter subunit beta; OST-beta; Solute carrier family 51 subunit beta", "protein_names_refseq": "OST-beta; organic solute transporter beta; organic solute transporter subunit beta; solute carrier family 51 beta subunit", "tax_id": 9913, "disease": "", "pathway": " (bta:507185); (R-BTA-159418)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential component of the OST-alpha/OST-beta complex, a heterotetramer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. The OST-alpha/OST-beta complex efficiently transports the major species of bile acids (taurocholate) (By similarity). Taurine conjugates are transported more efficiently across the basolateral membrane than glycine-conjugated bile acids (By similarity). In the complex, SLC51B/OST-beta promotes the transmembrane translocation of bile acids. Can also transport steroids such as estrone 3-sulfate and dehydroepiandrosterone 3-sulfate, therefore playing a role in the enterohepatic circulation of sterols (By similarity). Able to transport eicosanoids such as prostaglandin E2 (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0015125 bile acid transmembrane transporter activity;GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0016323 basolateral plasma membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0015721 bile acid and bile salt transport;GO:0031647 regulation of protein stability;GO:0090314 positive regulation of protein targeting to membrane;GO:0070863 positive regulation of protein exit from endoplasmic reticulum;GO:0010560 positive regulation of glycoprotein biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0JNM1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BJX8-1", "uniprot_id": "E1BJX8_BOVIN", "mass": 55709.0, "length": 503, "protein_name": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1", "gene_name": "PM20D1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PM20D1", "gene_names_refseq": "", "protein_names_uniprotkb": "N-fatty-acyl-amino acid synthase/hydrolase PM20D1; 3.5.1.114; 3.5.1.14; Peptidase M20 domain-containing protein 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-9673163)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Secreted enzyme that regulates the endogenous N-fatty acyl amino acid (NAAs) tissue and circulating levels by functioning as a bidirectional NAA synthase/hydrolase. It condenses free fatty acids and free amino acids to generate NAAs and bidirectionally catalyzes the reverse hydrolysis reaction. Some of these NAAs stimulate oxidative metabolism via mitochondrial uncoupling, increasing energy expenditure in a UPC1-independent manner. Thereby, this secreted protein may indirectly regulate whole body energy expenditure. PM20D1 circulates in tight association with both low- and high-density (LDL and HDL,respectively) lipoprotein particles., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.1.99;3.5.1.114;3.5.1.14", "go_molecular_function": "GO:0004046 aminoacylase activity;GO:0046872 metal ion binding;GO:0008233 peptidase activity;GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0006629 lipid metabolic process;GO:0006520 amino acid metabolic process;GO:0043604 amide biosynthetic process;GO:0043605 amide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BJX8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BBJ7-1", "uniprot_id": "E1BBJ7_BOVIN", "mass": 138998.0, "length": 1264, "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2", "gene_name": "INPPL1", "organism": "Bovine", "refseq_name": "phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2", "refseq_ac": "NP_001178105", "gene_names_uniprotkb": "INPPL1", "gene_names_refseq": "INPPL1", "protein_names_uniprotkb": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2; 3.1.3.86; Inositol polyphosphate phosphatase-like protein 1; Protein 51C; SH2 domain-containing inositol 5'-phosphatase 2", "protein_names_refseq": "phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2", "tax_id": 9913, "disease": "", "pathway": " (bta:783833); (R-BTA-1660499); (R-BTA-1855204); (R-BTA-912526)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;3.1.3.86;3.1.3.56;3.1.3.36;3.1.3.67;3.1.3.95;3.1.3.-;2.7.1.134;2.7.1.159", "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity;GO:0042169 SH2 domain binding;GO:0004445 inositol-polyphosphate 5-phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0016020 membrane;GO:0000922 spindle pole", "go_biological_process": "GO:0046856 phosphatidylinositol dephosphorylation;GO:0002376 immune system process;GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0050776 regulation of immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BBJ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6QLE5-1", "uniprot_id": "NLRP3_BOVIN", "mass": 118137.0, "length": 1031, "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "organism": "Bovine", "refseq_name": "NACHT, LRR and PYD domains-containing protein 3", "refseq_ac": "NP_001095689", "gene_names_uniprotkb": "NLRP3", "gene_names_refseq": "NLRP3", "protein_names_uniprotkb": "NACHT, LRR and PYD domains-containing protein 3; 3.6.4.-", "protein_names_refseq": "NACHT, LRR and PYD domains-containing protein 3", "tax_id": 9913, "disease": "", "pathway": " (bta:538639); (R-BTA-5689901); (R-BTA-844456)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "30186287;31903559;37626889", "class_list": "", "function": "Autophagy and NLRP3 inflammasome crosstalk in neuroinflammation in aged bovine brains., [RefSeq, PubMed]; Independently of inflammasome activation, regulates the differentiation of T helper 2 (Th2) cells and has a role in Th2 cell-dependent asthma and tumor growth. During Th2 differentiation, required for optimal IRF4 binding to IL4 promoter and for IRF4-dependent IL4 transcription. Binds to the consensus DNA sequence 5'-GRRGGNRGAG-3'. May also participate in the transcription of IL5, IL13, GATA3, CCR3, CCR4 and MAF., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Necrotic Cell Death and Inflammasome NLRP3 Activity in Mycobacterium bovis-Infected Bovine Macrophages. Publication Status: Online-Only, [RefSeq, PubMed]; Sensor component of the NLRP3 inflammasome, which mediates inflammasome activation in response to defects in membrane integrity, leading to secretion of inflammatory cytokines IL1B and IL18 and pyroptosis. In response to pathogens and other damage-associated signals that affect the integrity of membranes, initiates the formation of the inflammasome polymeric complex composed of NLRP3, CASP1 and PYCARD/ASC. Recruitment of pro-caspase-1 (proCASP1) to the NLRP3 inflammasome promotes caspase-1 (CASP1) activation, which subsequently cleaves and activates inflammatory cytokines IL1B and IL18 and gasdermin-D (GSDMD), promoting cytokine secretion and pyroptosis. Activation of NLRP3 inflammasome is also required for HMGB1 secretion; stimulating inflammatory responses (By similarity). Involved in the homeostatic wound healing response to tissue injury, a multistep cascade that guides neutrophil migration to necrotic sites while avoiding collateral damage of healthy tissues. ATP released from necrotic cells triggers activation of NLRP3 inflammasome through P2RX7 signaling leading to neutrophil adhesion to the vascular endothelium close to the injury site (By similarity). Under resting conditions, ADP-bound NLRP3 is autoinhibited (By similarity). NLRP3 activation stimuli include extracellular ATP, nigericin, reactive oxygen species, crystals of monosodium urate or cholesterol, amyloid-beta fibers, environmental or industrial particles and nanoparticles, such as asbestos, silica, aluminum salts, cytosolic dsRNA, etc. Almost all stimuli trigger intracellular K(+) efflux (By similarity). These stimuli lead to membrane perturbation and activation of NLRP3 (By similarity). Upon activation, NLRP3 is transported to microtubule organizing center (MTOC), where it is unlocked by NEK7, leading to its relocalization to dispersed trans-Golgi network (dTGN) vesicle membranes and formation of an active inflammasome complex. Associates with dTGN vesicle membranes by binding to phosphatidylinositol 4-phosphate (PtdIns4P). Shows ATPase activity (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Study highlights that miR-223 serves both to constrain the level of NLRP3 activation and to act as a protective factor in the inflammatory response and thus provides a future novel therapeutic modality for active flares in cow endometritis and other inflammatory diseases. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;3.4.19.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0043531 ADP binding;GO:0043565 sequence-specific DNA binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0009595 detection of biotic stimulus;GO:0044546 NLRP3 inflammasome complex assembly;GO:0006351 DNA-templated transcription;GO:0006954 inflammatory response;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A6QLE5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5PK74-1", "uniprot_id": "RIOX1_BOVIN", "mass": 74349.0, "length": 667, "protein_name": "Ribosomal oxygenase 1", "gene_name": "RIOX1", "organism": "Bovine", "refseq_name": "ribosomal oxygenase 1", "refseq_ac": "NP_001093172", "gene_names_uniprotkb": "RIOX1; MAPJD; NO66", "gene_names_refseq": "C10H14orf169; NO66; RIOX1", "protein_names_uniprotkb": "Ribosomal oxygenase 1; 1.14.11.27; 1.14.11.79; Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; Histone lysine demethylase NO66", "protein_names_refseq": "bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; histone lysine demethylase NO66; lysine-specific demethylase NO66; myc-associated protein with JmjC domain; nucleolar protein 66; ribosomal oxygenase 1", "tax_id": 9913, "disease": "", "pathway": " (bta:511031); (R-BTA-9629569)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23160351", "class_list": "", "function": "Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase (By similarity). Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation. Also catalyzes demethylation of non-histone proteins, such as CGAS: demethylation of monomethylated CGAS promotes interaction between CGAS and PARP1, followed by PARP1 inactivation (By similarity). Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216', thereby playing a role in ribosome biogenesis. Participates in MYC-induced transcriptional activation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation. Also catalyzes demethylation of non-histone proteins, such as CGAS: demethylation of monomethylated CGAS promotes interaction between CGAS and PARP1, followed by PARP1 inactivation. Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216', thereby playing a role in ribosome biogenesis. Participates in MYC-induced transcriptional activation., [UniProtKB, UniProtKB]; PHF19 associates with the H3K36me3 demethylase NO66, and it is required to recruit the PRC2 complex and NO66 to stem cell genes during differentiation, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.11.27;1.14.11.79;1.14.11.-", "go_molecular_function": "GO:0051864 histone H3K36 demethylase activity;GO:0034647 histone H3K4me/H3K4me2/H3K4me3 demethylase activity;GO:0032453 histone H3K4 demethylase activity;GO:0005506 iron ion binding;GO:0016706 2-oxoglutarate-dependent dioxygenase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0045668 negative regulation of osteoblast differentiation;GO:0006282 regulation of DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A5PK74-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00570-1", "uniprot_id": "KAD1_BOVIN", "mass": 21664.0, "length": 194, "protein_name": "Adenylate kinase isoenzyme 1", "gene_name": "AK1", "organism": "Bovine", "refseq_name": "adenylate kinase isoenzyme 1", "refseq_ac": "NP_001013600", "gene_names_uniprotkb": "AK1", "gene_names_refseq": "AK1", "protein_names_uniprotkb": "Adenylate kinase isoenzyme 1; 2.7.4.3; 2.7.4.4; 2.7.4.6; AK 1; ATP-AMP transphosphorylase 1; ATP:AMP phosphotransferase; Adenylate monophosphate kinase; Myokinase", "protein_names_refseq": "AK 1; ATP-AMP transphosphorylase 1; ATP:AMP phosphotransferase; adenylate kinase 1, soluble; adenylate kinase isoenzyme 1; adenylate monophosphate kinase; myokinase", "tax_id": 9913, "disease": "", "pathway": " (bta:280715); (R-BTA-499943)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "16305752;18235103;6089869", "class_list": "", "function": "Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity). Also catalyzes at a very low rate the synthesis of thiamine triphosphate (ThTP) from thiamine diphosphate (ThDP) and ADP (By similarity)., [UniProtKB, UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB]; The sperm-associated proteins, P25b and adenylate kinase 1, are linked to detergent-resistant membrane of epididymal spermatozoa, but were exclusively associated with detergent-soluble material in ejaculated spermatozoa., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5E9G9", "ec_number_list": "2.7.4.10;2.7.4.6;2.7.4.3;2.7.4.4;2.7.4.14;3.1.11.-;2.7.11.1;2.7.13.3;2.7.4.18;3.1.24.-", "go_molecular_function": "GO:0004017 AMP kinase activity;GO:0005524 ATP binding;GO:0004550 nucleoside diphosphate kinase activity;GO:0047506 dAMP kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0001520 outer dense fiber", "go_biological_process": "GO:0006172 ADP biosynthetic process;GO:0046033 AMP metabolic process;GO:0046034 ATP metabolic process;GO:0009142 nucleoside triphosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P00570-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0JNC4-1", "uniprot_id": "ELOV7_BOVIN", "mass": 33639.0, "length": 281, "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "organism": "Bovine", "refseq_name": "very long chain fatty acid elongase 7", "refseq_ac": "NP_001071510", "gene_names_uniprotkb": "ELOVL7", "gene_names_refseq": "ELOVL7", "protein_names_uniprotkb": "Very long chain fatty acid elongase 7; 2.3.1.199; 3-keto acyl-CoA synthase ELOVL7; ELOVL FA elongase 7; ELOVL fatty acid elongase 7; Elongation of very long chain fatty acids protein 7; Very long chain 3-ketoacyl-CoA synthase 7; Very long chain 3-oxoacyl-CoA synthase 7", "protein_names_refseq": "3-keto acyl-CoA synthase ELOVL7; ELOVL FA elongase 7; ELOVL family member 7, elongation of long chain fatty acids; elongation of very long chain fatty acids protein 7; very long chain 3-ketoacyl-CoA synthase 7; very long chain 3-oxoacyl-CoA synthase 7; very long chain fatty acid elongase 7", "tax_id": 9913, "disease": "", "pathway": " (bta:614096); (R-BTA-75876)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "29115671", "class_list": "", "function": "Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate in the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators., [UniProtKB, HAMAP]; Fatty acid elongase7 expression is regulated via SP1 and is involved in lipid accumulation in bovine mammary epithelial cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.199", "go_molecular_function": "GO:0009922 fatty acid elongase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030148 sphingolipid biosynthetic process;GO:0035338 long-chain fatty-acyl-CoA biosynthetic process;GO:0006636 unsaturated fatty acid biosynthetic process;GO:0034625 fatty acid elongation, monounsaturated fatty acid;GO:0034626 fatty acid elongation, polyunsaturated fatty acid", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0JNC4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0JNI4-1", "uniprot_id": "SRR_BOVIN", "mass": 36181.0, "length": 334, "protein_name": "Serine racemase", "gene_name": "SRR", "organism": "Bovine", "refseq_name": "serine racemase", "refseq_ac": "NP_001071433", "gene_names_uniprotkb": "SRR", "gene_names_refseq": "SRR", "protein_names_uniprotkb": "Serine racemase; 4.3.1.17; 4.3.1.18; 5.1.1.18; D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase", "protein_names_refseq": "D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; serine racemase", "tax_id": 9913, "disease": "", "pathway": " (bta:525340); (R-BTA-977347)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Pyridoxal-5'-phosphate (PLP)-dependent enzyme that catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. In addition to racemization, has dehydratase activity towards both L-serine and D-serine, a two-step reaction in which the hydroxyl group of serine is eliminated to produce aminoacrylate (2-aminoprop-2-enoate), and then the aminoacrylate (an unstable intermediate) is deaminated by nonenzymatic hydrolysis to produce pyruvate., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.3.1.17;4.3.1.18;5.1.1.18;4.3.1.19", "go_molecular_function": "GO:0008721 D-serine ammonia-lyase activity;GO:0030378 serine racemase activity;GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0030170 pyridoxal phosphate binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0070179 D-serine biosynthetic process;GO:0070178 D-serine metabolic process;GO:0006563 L-serine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0JNI4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1A4J1-1", "uniprot_id": "PFKAL_BOVIN", "mass": 85292.0, "length": 780, "protein_name": "ATP-dependent 6-phosphofructokinase, liver type", "gene_name": "PFKL", "organism": "Bovine", "refseq_name": "ATP-dependent 6-phosphofructokinase, liver type", "refseq_ac": "NP_001073713", "gene_names_uniprotkb": "PFKL", "gene_names_refseq": "ATP-PFK; PFK-L; PFKL", "protein_names_uniprotkb": "ATP-dependent 6-phosphofructokinase, liver type; 2.7.1.11; 6-phosphofructokinase type B; ATP-PFK; PFK-B; PFK-L; Phosphofructo-1-kinase isozyme B; Phosphohexokinase", "protein_names_refseq": "6-phosphofructokinase type B; 6-phosphofructokinase, liver type; ATP-dependent 6-phosphofructokinase, liver type; PFK-B; liver-type 1-phosphofructokinase; phosphofructo-1-kinase isozyme B; phosphofructokinase 1; phosphohexokinase", "tax_id": 9913, "disease": "", "pathway": " (bta:508683); (R-BTA-6798695); (R-BTA-70171)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (By similarity). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway (By similarity)., [UniProtKB, UniProtKB, HAMAP]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.42;2.5.1.18;2.7.1.1;2.7.11.24;3.2.1.23;2.4.2.1;5.2.1.8;4.1.2.13;3.6.1.6;2.3.2.27;3.1.6.14;3.6.4.13;1.1.1.205;2.7.1.11;2.7.11.22;2.7.11.23;2.3.2.26;2.4.1.25;3.2.1.33;4.2.99.18;5.6.2.4;3.6.4.12;3.4.23.5;1.13.11.34;1.13.11.12;3.6.4.6;1.16.3.1;1.11.1.6;3.4.18.1;3.4.22.1;3.6.4.10;3.4.22.27;3.4.24.35;3.6.5.-;3.1.1.47;5.3.2.1;5.3.3.12;3.4.19.1;2.7.1.35;2.4.1.1;3.5.1.23;3.5.1.-;3.4.22.52;2.3.3.8;5.4.2.11;5.4.2.4;3.3.2.6;3.4.11.4;3.4.21.46;2.7.4.6;2.7.13.3;4.1.2.4;5.3.1.9;5.1.3.-;3.6.1.-;2.4.2.7;4.2.1.24", "go_molecular_function": "GO:0070095 fructose-6-phosphate binding;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0019900 kinase binding", "go_cellular_component": "GO:0016020 membrane;GO:0005945 6-phosphofructokinase complex", "go_biological_process": "GO:0009749 response to glucose;GO:0006096 glycolytic process;GO:0030388 fructose 1,6-bisphosphate metabolic process;GO:0061621 canonical glycolysis;GO:0006002 fructose 6-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A1A4J1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1A4L1-1", "uniprot_id": "THEM4_BOVIN", "mass": 26812.0, "length": 237, "protein_name": "Acyl-coenzyme A thioesterase THEM4", "gene_name": "THEM4", "organism": "Bovine", "refseq_name": "acyl-coenzyme A thioesterase THEM4", "refseq_ac": "NP_001073837", "gene_names_uniprotkb": "THEM4", "gene_names_refseq": "THEM4", "protein_names_uniprotkb": "Acyl-coenzyme A thioesterase THEM4; 3.1.2.2; Acyl-CoA thioesterase THEM4; Thioesterase superfamily member 4", "protein_names_refseq": "acyl-CoA thioesterase THEM4; acyl-coenzyme A thioesterase THEM4", "tax_id": 9913, "disease": "", "pathway": " (bta:787270)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism (By similarity). Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.2.2;3.1.2.22;3.1.2.14;3.5.2.6;3.1.1.4;3.1.1.5;3.1.2.27;3.1.2.1;3.1.2.11;3.1.2.3;3.1.2.5;3.1.2.-;2.3.1.16;2.3.1.9", "go_molecular_function": "GO:0052816 long-chain fatty acyl-CoA hydrolase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005758 mitochondrial intermembrane space;GO:0005829 cytosol;GO:0032587 ruffle membrane", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A1A4L1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1A4L8-1", "uniprot_id": "MOCS3_BOVIN", "mass": 48834.0, "length": 455, "protein_name": "Adenylyltransferase and sulfurtransferase MOCS3", "gene_name": "MOCS3", "organism": "Bovine", "refseq_name": "adenylyltransferase and sulfurtransferase MOCS3", "refseq_ac": "NP_001075203", "gene_names_uniprotkb": "MOCS3; UBA4", "gene_names_refseq": "MOCS3", "protein_names_uniprotkb": "Adenylyltransferase and sulfurtransferase MOCS3; Adenylyltransferase MOCS3; Molybdenum cofactor synthesis protein 3; Sulfur carrier protein MOCS2A adenylyltransferase; Sulfur carrier protein MOCS2A sulfurtransferase; Sulfurtransferase MOCS3", "protein_names_refseq": "adenylyltransferase and sulfurtransferase MOCS3", "tax_id": 9913, "disease": "", "pathway": " (bta:539728); (R-BTA-947581)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as a nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 acting as a sulfur donor for thiocarboxylation reactions., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.7.80;2.8.1.11", "go_molecular_function": "GO:0016783 sulfurtransferase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016779 nucleotidyltransferase activity;GO:0004792 thiosulfate-cyanide sulfurtransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0002143 tRNA wobble position uridine thiolation;GO:0034227 tRNA thio-modification;GO:0002098 tRNA wobble uridine modification;GO:0006777 Mo-molybdopterin cofactor biosynthetic process;GO:0032447 protein urmylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A1A4L8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1A4N1-1", "uniprot_id": "S29A3_BOVIN", "mass": 51646.0, "length": 474, "protein_name": "Equilibrative nucleoside transporter 3", "gene_name": "SLC29A3", "organism": "Bovine", "refseq_name": "equilibrative nucleoside transporter 3", "refseq_ac": "NP_001073692", "gene_names_uniprotkb": "SLC29A3; ENT3", "gene_names_refseq": "SLC29A3", "protein_names_uniprotkb": "Equilibrative nucleoside transporter 3; Solute carrier family 29 member 3", "protein_names_refseq": "equilibrative nucleoside transporter 3; solute carrier family 29 (nucleoside transporters), member 3", "tax_id": 9913, "disease": "", "pathway": " (bta:504503)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Uniporter that mediates the facilitative transport of nucleoside across lysosomal and mitochondrial membranes. Functions as a non-electrogenic Na(+)-independent transporter. Transport activity is pH-dependent and enhanced under acidic conditions, consistent with localization to acidic intracellular compartments. Protons are not cotransported but likely modulate transport by altering the ionization state of the transporter which dictates its conformation, thereby regulating substrate permeability. May direct the nucleoside transport from lysosomes to cytosol or cytosol to mitochondria to facilitate nucleic acid salvage pathways. Transports nucleosides (adenosine, guanosine, uridine, thymidine, cytidine and inosine), deoxynucleosides (deoxyadenosine, deoxycytidine), purine nucleobases (adenine, guanine) and pyrimidine nucleobases (uracil). Also capable of transporting monoamine neurotransmitters dopamine, serotonin, noradrenaline and tyramine, as well as ATP (By similarity). Mediates nucleoside export from lysosomes in macrophages, thereby regulating macrophage function and number (By similarity). Also functions as a lysosomal urate exporter, contributing to intracellular urate disposal. Regulates inflammasome activation via dual roles in urate and adenosine transport (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0015205 nucleobase transmembrane transporter activity;GO:0015212 cytidine transmembrane transporter activity;GO:0015213 uridine transmembrane transporter activity;GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0031966 mitochondrial membrane;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0015851 nucleobase transport;GO:0015861 cytidine transport;GO:0015858 nucleoside transport;GO:0015862 uridine transmembrane transport;GO:0015872 dopamine transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A1A4N1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1A4Q9-1", "uniprot_id": "NUD16_BOVIN", "mass": 21399.0, "length": 195, "protein_name": "U8 snoRNA-decapping enzyme", "gene_name": "NUDT16", "organism": "Bovine", "refseq_name": "U8 snoRNA-decapping enzyme isoform X1", "refseq_ac": "XP_005202022", "gene_names_uniprotkb": "NUDT16", "gene_names_refseq": "NUDT16", "protein_names_uniprotkb": "U8 snoRNA-decapping enzyme; 3.6.1.62; 3.6.1.64; IDP phosphatase; IDPase; Inosine diphosphate phosphatase; Nucleoside diphosphate-linked moiety X motif 16; Nudix motif 16; m7GpppN-mRNA hydrolase", "protein_names_refseq": "U8 snoRNA-decapping enzyme isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2393930)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "RNA-binding and decapping enzyme that catalyzes the cleavage of the cap structure of snoRNAs and mRNAs in a metal-dependent manner. Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA. Has diphosphatase activity and removes m7G and/or m227G caps from U8 snoRNA and leaves a 5'monophosphate on the RNA. Also catalyzes the cleavage of the cap structure on mRNAs. Does not hydrolyze cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG). Also hydrolysis m7G- and m227G U3-capped RNAs but with less efficiencies. Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species. Binds to the U8 snoRNA; metal is not required for RNA-binding. May play a role in the regulation of snoRNAs and mRNAs degradation. Also acts as a phosphatase; hydrolyzes the non-canonical purine nucleotides inosine diphosphate (IDP) and deoxyinosine diphosphate (dITP) as well as guanosine diphosphate (GDP), deoxyguanosine diphosphate (dGDP), xanthine diphosphate (XDP), inosine triphosphate (ITP) and deoxyinosine triphosphate (ITP) to their respective monophosphate derivatives and does not distinguish between the deoxy- and ribose forms. The order of activity with different substrates is IDP > dIDP >> GDP = dGDP > XDP = ITP = dITP. Binds strongly to GTP, ITP and XTP. Participates in the hydrolysis of dIDP/IDP and probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions (By similarity). Exhibits decapping activity towards NAD-capped RNAs and FAD-capped RNAs (By similarity). Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.1.77;3.6.1.62;3.6.1.9;3.6.1.68;3.6.1.76;3.6.1.17;3.6.1.64;3.6.1.59;3.6.1.52;3.6.1.10;3.6.1.61;3.6.1.6;3.6.1.5;3.1.13.-;3.6.1.-", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003729 mRNA binding;GO:0030145 manganese ion binding;GO:0042803 protein homodimerization activity;GO:0000166 nucleotide binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006402 mRNA catabolic process;GO:0016077 sno(s)RNA catabolic process;GO:0035863 dITP catabolic process;GO:2000233 negative regulation of rRNA processing;GO:0090068 positive regulation of cell cycle process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A1A4Q9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A2VDM8-1", "uniprot_id": "BAP1_BOVIN", "mass": 78333.0, "length": 711, "protein_name": "Ubiquitin carboxyl-terminal hydrolase BAP1", "gene_name": "BAP1", "organism": "Bovine", "refseq_name": "ubiquitin carboxyl-terminal hydrolase BAP1", "refseq_ac": "NP_001096019", "gene_names_uniprotkb": "BAP1", "gene_names_refseq": "BAP1", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase BAP1; 3.4.19.12; BRCA1-associated protein 1", "protein_names_refseq": "ubiquitin carboxy-terminal hydrolase; ubiquitin carboxyl-terminal hydrolase BAP1", "tax_id": 9913, "disease": "", "pathway": " (bta:100124510)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the polycomb repressive deubiquitinase (PR-DUB) complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-120' (H2AK119ub1). Does not deubiquitinate monoubiquitinated histone H2B. The PR-DUB complex is an epigenetic regulator of gene expression and acts as a transcriptional coactivator, affecting genes involved in development, cell communication, signaling, cell proliferation and cell viability. Antagonizes PRC1 mediated H2AK119ub1 monoubiquitination. As part of the PR-DUB complex, associates with chromatin enriched in histone marks H3K4me1, H3K4me3, and H3K27Ac, but not in H3K27me3. Acts as a regulator of cell growth by mediating deubiquitination of HCFC1 N-terminal and C-terminal chains, with some specificity toward 'Lys-48'-linked polyubiquitin chains compared to 'Lys-63'-linked polyubiquitin chains. Deubiquitination of HCFC1 does not lead to increase stability of HCFC1. Interferes with the BRCA1 and BARD1 heterodimer activity by inhibiting their ability to mediate ubiquitination and autoubiquitination. It however does not mediate deubiquitination of BRCA1 and BARD1. Able to mediate autodeubiquitination via intramolecular interactions to counteract monoubiquitination at the nuclear localization signal (NLS), thereby protecting it from cytoplasmic sequestration. Negatively regulates epithelial-mesenchymal transition (EMT) of trophoblast stem cells during placental development by regulating genes involved in epithelial cell integrity, cell adhesion and cytoskeletal organization., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0035517 PR-DUB complex", "go_biological_process": "GO:0016579 protein deubiquitination;GO:0030154 cell differentiation;GO:0045892 negative regulation of DNA-templated transcription;GO:0001558 regulation of cell growth;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A2VDM8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A2VEA3-1", "uniprot_id": "ARI1_BOVIN", "mass": 64017.0, "length": 555, "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase ARIH1", "refseq_ac": "NP_001075183", "gene_names_uniprotkb": "ARIH1", "gene_names_refseq": "ARIH1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase ARIH1; 2.3.2.31; ARI-1; Protein ariadne-1 homolog", "protein_names_refseq": "ARI-1; E3 ubiquitin-protein ligase ARIH1; Protein ariadne-1 homolog; RING-type E3 ubiquitin transferase ARIH1; ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1", "tax_id": 9913, "disease": "", "pathway": " (bta:508410); (R-BTA-1169408); (R-BTA-9833482); (R-BTA-9909505)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3. Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-RING ubiquitin ligase (CRL) complexes and initiating ubiquitination of CRL substrates: associates with CRL complexes and specifically mediates addition of the first ubiquitin on CRLs targets. The initial ubiquitin is then elongated by CDC34/UBE2R1 and UBE2R2. E3 ubiquitin-protein ligase activity is activated upon binding to neddylated cullin-RING ubiquitin ligase complexes. Plays a role in protein translation in response to DNA damage by mediating ubiquitination of EIF4E2, the consequences of EIF4E2 ubiquitination are however unclear. According to a report, EIF4E2 ubiquitination leads to promote EIF4E2 cap-binding and protein translation arrest. According to another report EIF4E2 ubiquitination leads to its subsequent degradation. Acts as the ligase involved in ISGylation of EIF4E2. In vitro, controls the degradation of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex member SUN2 and may therefore have a role in the formation and localization of the LINC complex, and as a consequence, may act in nuclear subcellular localization and nuclear morphology., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.23;3.6.4.13;2.7.10.2;2.3.2.31;2.7.11.24;3.1.3.16", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0031624 ubiquitin conjugating enzyme binding;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016604 nuclear body;GO:0000151 ubiquitin ligase complex;GO:0015030 Cajal body", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A2VEA3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A4K436-1", "uniprot_id": "RTEL1_BOVIN", "mass": 134448.0, "length": 1216, "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "organism": "Bovine", "refseq_name": "regulator of telomere elongation helicase 1", "refseq_ac": "NP_001091044", "gene_names_uniprotkb": "RTEL1", "gene_names_refseq": "RTEL1; RTEL", "protein_names_uniprotkb": "Regulator of telomere elongation helicase 1; 5.6.2.-", "protein_names_refseq": "regulator of telomere elongation helicase 1; regulator of telomere length helicase 1", "tax_id": 9913, "disease": "", "pathway": " (bta:505721)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17338827", "class_list": "", "function": "A probable ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere., [UniProtKB, HAMAP]; Cloned a bovine regulator of telomere length elongation helicase (RTEL) homolog and characterized its gene structure, expression distribution, splice variants and profile of DNA methylation around two putative transcription start sites. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4K3A3;A4K434;A4K435;A5J092", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0090657 telomeric loop disassembly;GO:1904430 negative regulation of t-circle formation;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0000723 telomere maintenance", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A4K436-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5D7F8-1", "uniprot_id": "SH3R1_BOVIN", "mass": 87592.0, "length": 840, "protein_name": "E3 ubiquitin-protein ligase SH3RF1", "gene_name": "SH3RF1", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase SH3RF1", "refseq_ac": "NP_001091534", "gene_names_uniprotkb": "SH3RF1; POSH1; POSH", "gene_names_refseq": "SH3RF1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase SH3RF1; 2.3.2.27; Plenty of SH3s; Protein POSH; RING-type E3 ubiquitin transferase SH3RF1; SH3 domain-containing RING finger protein 1", "protein_names_refseq": "E3 ubiquitin-protein ligase SH3RF1; RING-type E3 ubiquitin transferase SH3RF1; SH3 domain-containing RING finger protein 1; plenty of SH3s; putative E3 ubiquitin-protein ligase SH3RF1", "tax_id": 9913, "disease": "", "pathway": " (bta:528315); (R-BTA-9013424); (R-BTA-983168)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Has E3 ubiquitin-protein ligase activity. In the absence of an external substrate, it can catalyze self-ubiquitination. Stimulates ubiquitination of potassium channel KCNJ1, enhancing its dynamin-dependent and clathrin-independent endocytosis. Acts as a scaffold protein that coordinates with MAPK8IP1/JIP1 in organizing different components of the JNK pathway, including RAC1 or RAC2, MAP3K11/MLK3 or MAP3K7/TAK1, MAP2K7/MKK7, MAPK8/JNK1 and/or MAPK9/JNK2 into a functional multiprotein complex to ensure the effective activation of the JNK signaling pathway. Regulates the differentiation of CD4(+) and CD8(+) T-cells and promotes T-helper 1 (Th1) cell differentiation. Regulates the activation of MAPK8/JNK1 and MAPK9/JNK2 in CD4(+) T-cells and the activation of MAPK8/JNK1 in CD8(+) T-cells. Plays a crucial role in the migration of neocortical neurons in the developing brain. Controls proper cortical neuronal migration and the formation of proximal cytoplasmic dilation in the leading process (PCDLP) in migratory neocortical neurons by regulating the proper localization of activated RAC1 and F-actin assembly., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.27;2.7.11.1;2.3.2.23;2.3.2.31;3.4.19.12;2.3.2.26;2.3.2.-;2.3.2.34;2.3.2.25;2.7.10.1;2.7.11.25;2.3.2.24;3.6.5.2", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0005078 MAP-kinase scaffold activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0030027 lamellipodium;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:2000564 regulation of CD8-positive, alpha-beta T cell proliferation;GO:0043066 negative regulation of apoptotic process;GO:0046330 positive regulation of JNK cascade;GO:0001764 neuron migration;GO:0051865 protein autoubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A5D7F8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5H631-1", "uniprot_id": "A5H631_BOVIN", "mass": 115484.0, "length": 1029, "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TLR9", "gene_names_refseq": "", "protein_names_uniprotkb": "Toll-like receptor 9", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-109704); (R-BTA-1679131); (R-BTA-168138)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also acts via ADCY7, leading to cyclic di-AMP (c-di-AMP) synthesis and activation of the NLRP3 inflammasome. Plays a role in defense against systemic mouse cytomegalovirus infection. Controls lymphocyte response to Helicobacter infection. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035197 siRNA binding;GO:0045322 unmethylated CpG binding;GO:0005149 interleukin-1 receptor binding;GO:0038187 pattern recognition receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0016324 apical plasma membrane;GO:0031901 early endosome membrane", "go_biological_process": "GO:0045577 regulation of B cell differentiation;GO:0032727 positive regulation of interferon-alpha production;GO:0032741 positive regulation of interleukin-18 production;GO:0006954 inflammatory response;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A5H631-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5PK42-1", "uniprot_id": "ODAD4_BOVIN", "mass": 78368.0, "length": 683, "protein_name": "Outer dynein arm-docking complex subunit 4", "gene_name": "ODAD4", "organism": "Bovine", "refseq_name": "outer dynein arm-docking complex subunit 4", "refseq_ac": "NP_001096778", "gene_names_uniprotkb": "ODAD4; TTC25", "gene_names_refseq": "ODAD4; TTC25", "protein_names_uniprotkb": "Outer dynein arm-docking complex subunit 4; TPR repeat protein 25; Tetratricopeptide repeat protein 25", "protein_names_refseq": "TPR repeat protein 25; outer dynein arm-docking complex subunit 4; tetratricopeptide repeat domain 25; tetratricopeptide repeat protein 25", "tax_id": 9913, "disease": "", "pathway": " (bta:788831)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "19393038;34715025", "class_list": "", "function": "Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule. Plays an essential role for the assembly of ODA-DC and for the docking of ODA in ciliary axoneme., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1MKD0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0097729 9+2 motile cilium;GO:0097728 9+0 motile cilium;GO:0120228 outer dynein arm docking complex", "go_biological_process": "GO:0003341 cilium movement;GO:0036158 outer dynein arm assembly;GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry;GO:0120197 mucociliary clearance;GO:0120229 protein localization to motile cilium", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A5PK42-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5PKJ4-1", "uniprot_id": "MK07_BOVIN", "mass": 84832.0, "length": 781, "protein_name": "Mitogen-activated protein kinase 7", "gene_name": "MAPK7", "organism": "Bovine", "refseq_name": "mitogen-activated protein kinase 7", "refseq_ac": "NP_001092550", "gene_names_uniprotkb": "MAPK7", "gene_names_refseq": "ERK-5; MAPK7", "protein_names_uniprotkb": "Mitogen-activated protein kinase 7; 2.7.11.24; MAP kinase 7; MAPK 7", "protein_names_refseq": "BMK1 kinase; Big MAP kinase 1; Extracellular signal-regulated kinase 5; MAP kinase 7; MAPK 7; mitogen-activated protein kinase 7", "tax_id": 9913, "disease": "", "pathway": " (bta:537703); (R-BTA-198753); (R-BTA-198765); (R-BTA-202670); (R-BTA-2559582); (R-BTA-881907); (R-BTA-8853659)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. As part of the MAPK/ERK signaling pathway, acts as a negative regulator of apoptosis in cardiomyocytes via interaction with STUB1/CHIP and promotion of STUB1-mediated ubiquitination and degradation of ICER-type isoforms of CREM (By similarity). May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression (By similarity). Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;3.1.3.16;3.1.3.48;2.7.11.38;2.7.10.1;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004707 MAP kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016605 PML body", "go_biological_process": "GO:0030154 cell differentiation;GO:0035556 intracellular signal transduction;GO:0000165 MAPK cascade;GO:0034392 negative regulation of smooth muscle cell apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A5PKJ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6H737-1", "uniprot_id": "LOXL2_BOVIN", "mass": 86785.0, "length": 774, "protein_name": "Lysyl oxidase homolog 2", "gene_name": "LOXL2", "organism": "Bovine", "refseq_name": "lysyl oxidase homolog 2 precursor", "refseq_ac": "NP_001092523", "gene_names_uniprotkb": "LOXL2", "gene_names_refseq": "LOXL2", "protein_names_uniprotkb": "Lysyl oxidase homolog 2; 1.4.3.13; Lysyl oxidase-like protein 2", "protein_names_refseq": "lysyl oxidase homolog 2 precursor; lysyl oxidase homolog 2; lysyl oxidase-like protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:532684); (R-BTA-1566948); (R-BTA-2243919)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Shows no activity against histone H3 when it is trimethylated on 'Lys-9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2). Also mediates deamination of methylated TAF10, a member of the transcription factor IID (TFIID) complex, which induces release of TAF10 from promoters, leading to inhibition of TFIID-dependent transcription. LOXL2-mediated deamination of TAF10 results in transcriptional repression of genes required for embryonic stem cell pluripotency including POU5F1/OCT4, NANOG, KLF4 and SOX2. Involved in epithelial to mesenchymal transition (EMT) via interaction with SNAI1 and participates in repression of E-cadherin CDH1, probably by mediating deamination of histone H3. During EMT, involved with SNAI1 in negatively regulating pericentromeric heterochromatin transcription. SNAI1 recruits LOXL2 to pericentromeric regions to oxidize histone H3 and repress transcription which leads to release of heterochromatin component CBX5/HP1A, enabling chromatin reorganization and acquisition of mesenchymal traits. Interacts with the endoplasmic reticulum protein HSPA5 which activates the IRE1-XBP1 pathway of the unfolded protein response, leading to expression of several transcription factors involved in EMT and subsequent EMT induction. When secreted into the extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "F6RUG1", "ec_number_list": "1.4.3.13;3.4.24.-", "go_molecular_function": "GO:0070492 oligosaccharide binding;GO:0005509 calcium ion binding;GO:0005507 copper ion binding;GO:0004720 protein-lysine 6-oxidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0031012 extracellular matrix", "go_biological_process": "GO:0036211 protein modification process;GO:1902455 negative regulation of stem cell population maintenance;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0001666 response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A6H737-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6H7I5-1", "uniprot_id": "DYN2_BOVIN", "mass": 97836.0, "length": 866, "protein_name": "Dynamin-2", "gene_name": "DNM2", "organism": "Bovine", "refseq_name": "dynamin-2", "refseq_ac": "NP_001092839", "gene_names_uniprotkb": "DNM2", "gene_names_refseq": "DNM2", "protein_names_uniprotkb": "Dynamin-2; 3.6.5.5", "protein_names_refseq": "dynamin-2", "tax_id": 9913, "disease": "", "pathway": " (bta:511691)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12488320;17682044;18765728;23940613;30573663", "class_list": "", "function": "Catalyzes the hydrolysis of GTP and utilizes this energy to mediate vesicle scission at plasma membrane during endocytosis and filament remodeling at many actin structures during organization of the actin cytoskeleton. Plays an important role in vesicular trafficking processes, namely clathrin-mediated endocytosis (CME), exocytic and clathrin-coated vesicle from the trans-Golgi network, and PDGF stimulated macropinocytosis. During vesicular trafficking process, associates to the membrane, through lipid binding, and self-assembles into ring-like structure through oligomerization to form a helical polymer around the vesicle membrane and leading to vesicle scission (By similarity). Plays a role in organization of the actin cytoskeleton by mediating arrangement of stress fibers and actin bundles in podocytes. During organization of the actin cytoskeleton, self-assembles into ring-like structure that directly bundles actin filaments to form typical membrane tubules decorated with dynamin spiral polymers (By similarity). Self-assembly increases GTPase activity and the GTP hydrolysis causes the rapid depolymerization of dynamin spiral polymers, and results in dispersion of actin bundles (By similarity). Remodels, through its interaction with CTTN, bundled actin filaments in a GTPase-dependent manner and plays a role in orchestrating the global actomyosin cytoskeleton (By similarity). The interaction with CTTN stabilizes the interaction of DNM2 and actin filaments and stimulates the intrinsic GTPase activity that results in actin filament-barbed ends and increases the sensitivity of filaments in bundles to the actin depolymerizing factor, CFL1 (By similarity). Plays a role in the autophagy process, by participating in the formation of ATG9A vesicles destined for the autophagosomes through its interaction with SNX18, by mediating recycling endosome scission leading to autophagosome release through MAP1LC3B interaction (By similarity). Also regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity). Also plays a role in cytokinesis (By similarity). May participate in centrosome cohesion through its interaction with TUBG1. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Involved in membrane tubulation (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Dynamin-2 directs actin polymerization at the exocytosis site where both, in concert, adjust the hormone quantal release. Publication Status: Online-Only, [RefSeq, PubMed]; Knocking down dynamin-2 by small interfering RNA reduced both leukotoxin internalization and cytotoxicity., [RefSeq, PubMed]; LKT-mediated cell death involve dynamin-2 and cyclophilin D, [RefSeq, PubMed]; Role of the proline-rich domain of dynamin-2 in in vitro potentiation of endothelial nitric-oxide synthase activity., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005813 centrosome;GO:0005874 microtubule", "go_biological_process": "GO:0097749 membrane tubulation;GO:0061572 actin filament bundle organization;GO:0031623 receptor internalization;GO:0006909 phagocytosis;GO:0048812 neuron projection morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A6H7I5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6H7J1-1", "uniprot_id": "INSM1_BOVIN", "mass": 53935.0, "length": 522, "protein_name": "Insulinoma-associated protein 1", "gene_name": "INSM1", "organism": "Bovine", "refseq_name": "insulinoma-associated protein 1", "refseq_ac": "NP_001094700", "gene_names_uniprotkb": "INSM1; IA1", "gene_names_refseq": "IA1; INSM1", "protein_names_uniprotkb": "Insulinoma-associated protein 1; Zinc finger protein IA-1", "protein_names_refseq": "insulinoma-associated 1; insulinoma-associated protein 1; zinc finger protein IA-1", "tax_id": 9913, "disease": "", "pathway": " (bta:100137721)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Sequence-specific DNA-binding transcriptional regulator that plays a key role in neurogenesis and neuroendocrine cell differentiation during embryonic and/or fetal development. Binds to the consensus sequence 5'-[TG][TC][TC][TT][GA]GGG[CG]A-3' in target promoters. Acts as a transcriptional repressor of NEUROD1 and INS expression via its interaction with cyclin CCND1 in a cell cycle-independent manner. Negatively regulates skeletal muscle-specific gene expression in endocrine cells of the pituitary by inhibiting the Notch signaling pathway. Represses target gene transcription by recruiting chromatin-modifying factors, such as HDAC1, HDAC2, HDAC3, KDM1A and RCOR1 histone deacetylases. Binds to its own promoter, suggesting autoregulation as a self-control feedback mechanism. Competes with histone H3 for the same binding site on the histone demethylase complex formed by KDM1A and RCOR1, and thereby inhibits demethylation of histone H3 at 'Lys-4'. Promotes the generation and expansion of neuronal basal progenitor cells in the developing neocortex. Involved in the differentiation of endocrine cells of the developing anterior pituitary gland, of the pancreas and intestine, and of sympatho-adrenal cells in the peripheral nervous system. Promotes cell cycle signaling arrest and inhibition of cellular proliferation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0017053 transcription repressor complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0008285 negative regulation of cell population proliferation;GO:0001933 negative regulation of protein phosphorylation;GO:0045597 positive regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6H7J1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6QLI1-1", "uniprot_id": "VGLU2_BOVIN", "mass": 64546.0, "length": 582, "protein_name": "Vesicular glutamate transporter 2", "gene_name": "SLC17A6", "organism": "Bovine", "refseq_name": "vesicular glutamate transporter 2", "refseq_ac": "NP_001096580", "gene_names_uniprotkb": "SLC17A6; VGLUT2", "gene_names_refseq": "SLC17A6; VGluT2", "protein_names_uniprotkb": "Vesicular glutamate transporter 2; Solute carrier family 17 member 6; VGluT2", "protein_names_refseq": "solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; vesicular glutamate transporter 2", "tax_id": 9913, "disease": "", "pathway": " (bta:100125225); (R-BTA-442660)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Multifunctional transporter that transports L-glutamate as well as multiple ions such as chloride, proton, potassium, sodium and phosphate. At the synaptic vesicle membrane, mainly functions as a uniporter which transports preferentially L-glutamate but also, phosphate from the cytoplasm into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. The L-glutamate or phosphate uniporter activity is electrogenic and is driven by the proton electrochemical gradient, mainly by the electrical gradient established by the vacuolar H(+)-ATPase across the synaptic vesicle membrane. In addition, functions as a chloride channel that allows a chloride permeation through the synaptic vesicle membrane therefore affects the proton electrochemical gradient and promotes synaptic vesicles acidification. Moreover, functions as a vesicular K(+)/H(+) antiport allowing to maintain the electrical gradient and to decrease chemical gradient and therefore sustain vesicular L-glutamate uptake. The vesicular H(+)/H(+) antiport activity is electroneutral. At the plasma membrane, following exocytosis, functions as a symporter of Na(+) and phosphate from the extracellular space to the cytoplasm allowing synaptic phosphate homeostasis regulation. The symporter activity is driven by an inside negative membrane potential and is electrogenic (By similarity). Also involved in the regulation of retinal hyaloid vessel regression during postnatal development (By similarity). May also play a role in the endocrine L-glutamatergic system of other tissues such as pineal gland and pancreas (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.1.6;1.8.-.-;1.8.5.1", "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0015386 potassium:proton antiporter activity;GO:0005254 chloride channel activity;GO:0005313 L-glutamate transmembrane transporter activity;GO:0005436 sodium:phosphate symporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043005 neuron projection;GO:0030672 synaptic vesicle membrane;GO:0034707 chloride channel complex;GO:0008021 synaptic vesicle", "go_biological_process": "GO:1990384 hyaloid vascular plexus regression;GO:0050803 regulation of synapse structure or activity;GO:0035249 synaptic transmission, glutamatergic;GO:0055062 phosphate ion homeostasis;GO:0006817 phosphate ion transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6QLI1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6QLW8-1", "uniprot_id": "S22A7_BOVIN", "mass": 60004.0, "length": 547, "protein_name": "Solute carrier family 22 member 7", "gene_name": "SLC22A7", "organism": "Bovine", "refseq_name": "solute carrier family 22 member 7", "refseq_ac": "NP_001094517", "gene_names_uniprotkb": "SLC22A7; OAT2", "gene_names_refseq": "SLC22A7; oat2", "protein_names_uniprotkb": "Solute carrier family 22 member 7; Organic anion transporter 2", "protein_names_refseq": "organic anion transporter 2; solute carrier family 22 member 7", "tax_id": 9913, "disease": "", "pathway": " (bta:407224)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as a Na(+)-independent bidirectional multispecific transporter. Contributes to the renal and hepatic elimination of endogenous organic compounds from the systemic circulation into the urine and bile, respectively. Capable of transporting a wide range of purine and pyrimidine nucleobases, nucleosides and nucleotides, with cGMP, 2'deoxyguanosine and GMP being the preferred substrates. Functions as a pH- and chloride-independent cGMP bidirectional facilitative transporter that can regulate both intracellular and extracellular levels of cGMP and may be involved in cGMP signaling pathways. Mediates orotate/glutamate bidirectional exchange and most likely display a physiological role in hepatic release of glutamate into the blood. Involved in renal secretion and possible reabsorption of creatinine. Able to uptake prostaglandin E2 (PGE2) and may contribute to PGE2 renal excretion. Also transports alpha-ketoglutarate and urate. Apart from the orotate/glutamate exchange, the counterions for the uptake of other SLC22A7/OAT2 substrates remain to be identified., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015139 alpha-ketoglutarate transmembrane transporter activity;GO:0022857 transmembrane transporter activity;GO:0015291 secondary active transmembrane transporter activity;GO:0015132 prostaglandin transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0009925 basal plasma membrane", "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0015742 alpha-ketoglutarate transport;GO:0015732 prostaglandin transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6QLW8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6QP16-1", "uniprot_id": "ZRAN1_BOVIN", "mass": 81047.0, "length": 708, "protein_name": "Ubiquitin thioesterase ZRANB1", "gene_name": "ZRANB1", "organism": "Bovine", "refseq_name": "ubiquitin thioesterase ZRANB1", "refseq_ac": "NP_001094584", "gene_names_uniprotkb": "ZRANB1", "gene_names_refseq": "ZRANB1", "protein_names_uniprotkb": "Ubiquitin thioesterase ZRANB1; 3.4.19.12; Zinc finger Ran-binding domain-containing protein 1", "protein_names_refseq": "Zinc finger Ran-binding domain-containing protein 1; ubiquitin thioesterase ZRANB1; zinc finger, RAN-binding domain containing 1 protein", "tax_id": 9913, "disease": "", "pathway": " (bta:523338); (R-BTA-195253); (R-BTA-5689896)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "25752573", "class_list": "", "function": "Ubiquitin thioesterase, which specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin (By similarity). Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones (By similarity). Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription (By similarity). Acts as a regulator of autophagy by mediating deubiquitination of PIK3C3/VPS34, thereby promoting autophagosome maturation (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity). Required in the stress fiber dynamics and cell migration (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.19.12;2.3.2.27", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0070530 K63-linked polyubiquitin modification-dependent protein binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0070536 protein K63-linked deubiquitination;GO:0016055 Wnt signaling pathway;GO:0090263 positive regulation of canonical Wnt signaling pathway;GO:0030177 positive regulation of Wnt signaling pathway;GO:0035523 protein K29-linked deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A6QP16-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6QP84-1", "uniprot_id": "SOAT_BOVIN", "mass": 41438.0, "length": 377, "protein_name": "Sodium-dependent organic anion transporter", "gene_name": "SLC10A6", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC10A6; SOAT", "gene_names_refseq": "", "protein_names_uniprotkb": "Sodium-dependent organic anion transporter; SLC10A6; Soat; Solute carrier family 10 member 6", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:540841)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transports sulfoconjugated steroid hormones from the extracellular compartment into the cytosol in a sodium-dependent manner without hydrolysis. Steroid sulfate hormones are commonly considered to be biologically inactive metabolites, that may be activated by steroid sulfatases into free steroids (By similarity). May play an important role by delivering sulfoconjugated steroids to specific target cells in reproductive organs (By similarity). May play a role transporting the estriol precursor 16alpha-hydroxydehydroepiandrosterone 3-sulfate (16a-OH-DHEAS) at the fetal blood vessel endothelium (By similarity). Can also transport other sulfoconjugated molecules such as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A2IB93;A4ZYB2;A4ZYB3;A4ZYB4;Q206K3", "ec_number_list": "", "go_molecular_function": "GO:0008508 bile acid:sodium symporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0015721 bile acid and bile salt transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A6QP84-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A6QQL0-1", "uniprot_id": "S15A4_BOVIN", "mass": 61380.0, "length": 566, "protein_name": "Solute carrier family 15 member 4", "gene_name": "SLC15A4", "organism": "Bovine", "refseq_name": "solute carrier family 15 member 4", "refseq_ac": "NP_001095397", "gene_names_uniprotkb": "SLC15A4; PHT1", "gene_names_refseq": "SLC15A4", "protein_names_uniprotkb": "Solute carrier family 15 member 4; Peptide/histidine transporter 1", "protein_names_refseq": "peptide transporter 4; peptide/histidine transporter 1; solute carrier family 15 member 4", "tax_id": 9913, "disease": "", "pathway": " (bta:510499); (R-BTA-427975); (R-BTA-6798695); (R-BTA-9860276)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "14567629", "class_list": "", "function": "Proton-coupled amino-acid transporter that mediates the transmembrane transport of L-histidine and some di- and tripeptides from inside the lysosome to the cytosol, and plays a key role in innate immune response. Preferably binds to short peptides with a basic residue at the first position and a hydrophobic residue at the second position (By similarity). Able to transport a variety of di- and tripeptides, including carnosine and some peptidoglycans (By similarity). Transporter activity is pH-dependent and maximized in the acidic lysosomal environment (By similarity). Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand, and L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate (tri-DAP), the NOD1 ligand. Required for TLR7, TLR8 and TLR9-mediated type I interferon (IFN-I) productions in plasmacytoid dendritic cells (pDCs). Independently of its transporter activity, also promotes the recruitment of innate immune adapter TASL to endolysosome downstream of TLR7, TLR8 and TLR9: TASL recruitment leads to the specific recruitment and activation of IRF5 (By similarity). Required for isotype class switch recombination to IgG2c isotype in response to TLR9 stimulation. Required for mast cell secretory-granule homeostasis by limiting mast cell functions and inflammatory responses (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005290 L-histidine transmembrane transporter activity;GO:0015333 peptide:proton symporter activity;GO:0071916 dipeptide transmembrane transporter activity;GO:0015647 peptidoglycan transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0005765 lysosomal membrane;GO:0031901 early endosome membrane;GO:0036020 endolysosome membrane", "go_biological_process": "GO:0048302 regulation of isotype switching to IgG isotypes;GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway;GO:0015031 protein transport;GO:0045087 innate immune response;GO:0034157 positive regulation of toll-like receptor 7 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A6QQL0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A7MBI0-1", "uniprot_id": "PACN1_BOVIN", "mass": 50658.0, "length": 444, "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "organism": "Bovine", "refseq_name": "protein kinase C and casein kinase substrate in neurons protein 1", "refseq_ac": "NP_001094571", "gene_names_uniprotkb": "PACSIN1", "gene_names_refseq": "PACSIN1", "protein_names_uniprotkb": "Protein kinase C and casein kinase substrate in neurons protein 1", "protein_names_refseq": "protein kinase C and casein kinase substrate in neurons protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:520488); (R-BTA-8856828)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds to membranes via its F-BAR domain and mediates membrane tubulation. Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT; this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization. Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex. Plays a role in the regulation of neurite formation, neurite branching and the regulation of neurite length. Required for normal synaptic vesicle endocytosis; this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission. Required for normal excitatory and inhibitory synaptic transmission (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7Z043", "ec_number_list": "", "go_molecular_function": "GO:0005543 phospholipid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0043679 axon terminus", "go_biological_process": "GO:0007015 actin filament organization;GO:0030100 regulation of endocytosis;GO:0048812 neuron projection morphogenesis;GO:0007010 cytoskeleton organization;GO:0072657 protein localization to membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A7MBI0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A7YW45-1", "uniprot_id": "ANM5_BOVIN", "mass": 72629.0, "length": 637, "protein_name": "Protein arginine N-methyltransferase 5", "gene_name": "PRMT5", "organism": "Bovine", "refseq_name": "protein arginine N-methyltransferase 5", "refseq_ac": "NP_001098844", "gene_names_uniprotkb": "PRMT5; SKB1", "gene_names_refseq": "PRMT5; SKB1", "protein_names_uniprotkb": "Protein arginine N-methyltransferase 5; 2.1.1.320; Histone-arginine N-methyltransferase PRMT5; PRMT5; SKB1 homolog; Shk1 kinase-binding protein 1 homolog", "protein_names_refseq": "SKB1 homolog; histone-arginine N-methyltransferase PRMT5; protein arginine N-methyltransferase 5; shk1 kinase-binding protein 1 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:515594)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32560231", "class_list": "", "function": "Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H and may regulate its transcriptional elongation properties (By similarity). May methylate the N-terminal region of MBD2 (By similarity). Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. Methylates histone H2A and H4 'Arg-3' during germ cell development (By similarity). Methylates histone H3 'Arg-8', which may repress transcription (By similarity). Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage (By similarity). Methylates RPS10. Attenuates EGF signaling through the MAPK1/MAPK3 pathway acting at 2 levels. First, monomethylates EGFR; this enhances EGFR 'Tyr-1197' phosphorylation and PTPN6 recruitment, eventually leading to reduced SOS1 phosphorylation. Second, methylates RAF1 and probably BRAF, hence destabilizing these 2 signaling proteins and reducing their catalytic activity. Required for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation. Methylates HOXA9. Methylates and regulates SRGAP2 which is involved in cell migration and differentiation (By similarity). Acts as a transcriptional corepressor in CRY1-mediated repression of the core circadian component PER1 by regulating the H4R3 dimethylation at the PER1 promoter (By similarity). Methylates GM130/GOLGA2, regulating Golgi ribbon formation. Methylates H4R3 in genes involved in glioblastomagenesis in a CHTOP- and/or TET1-dependent manner. Symmetrically methylates POLR2A, a modification that allows the recruitment to POLR2A of proteins including SMN1/SMN2 and SETX. This is required for resolving RNA-DNA hybrids created by RNA polymerase II, that form R-loop in transcription terminal regions, an important step in proper transcription termination. Along with LYAR, binds the promoter of gamma-globin HBG1/HBG2 and represses its expression. Symmetrically methylates NCL. Methylates p53/TP53; methylation might possibly affect p53/TP53 target gene specificity (By similarity). Involved in spliceosome maturation and mRNA splicing in prophase I spermatocytes through the catalysis of the symmetrical arginine dimethylation of SNRPB (small nuclear ribonucleoprotein-associated protein) and the interaction with tudor domain-containing protein TDRD6 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; PRMT5 Is Required for Bovine Leukemia Virus Infection In Vivo and Regulates BLV Gene Expression, Syncytium Formation, and Glycosylation In Vitro. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.320", "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0008327 methyl-CpG binding;GO:0016274 protein-arginine N-methyltransferase activity;GO:0044020 histone H4R3 methyltransferase activity;GO:0035243 protein-arginine omega-N symmetric methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0034709 methylosome;GO:0035097 histone methyltransferase complex", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0018216 peptidyl-arginine methylation;GO:0042118 endothelial cell activation;GO:0032922 circadian regulation of gene expression;GO:0000387 spliceosomal snRNP assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A7YW45-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A7YY44-1", "uniprot_id": "PAR1_BOVIN", "mass": 46818.0, "length": 427, "protein_name": "Proteinase-activated receptor 1", "gene_name": "F2R", "organism": "Bovine", "refseq_name": "proteinase-activated receptor 1 precursor", "refseq_ac": "NP_001096567", "gene_names_uniprotkb": "F2R; PAR1", "gene_names_refseq": "F2R; PAR1", "protein_names_uniprotkb": "Proteinase-activated receptor 1; PAR-1; Thrombin receptor", "protein_names_refseq": "PAR-1; protease-activated receptor 1; proteinase-activated receptor 1 precursor; proteinase-activated receptor 1; thrombin receptor", "tax_id": 9913, "disease": "", "pathway": " (bta:526585)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "19064814;23155052", "class_list": "", "function": "High affinity receptor that binds the activated thrombin, leading to calcium release from intracellular stores. The thrombin-activated receptor signaling pathway is mediated through PTX-insensitive G proteins, activation of phospholipase C resulting in the production of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) which binds to InsP3 receptors causing calcium release from the stores (By similarity). In astrocytes, the calcium released into the cytosol allows the Ca(2+)-dependent release of L-glutamate into the synaptic cleft through BEST1, that targets the neuronal postsynaptic GRIN2A/NMDAR receptor resulting in the synaptic plasticity regulation (By similarity). May play a role in platelets activation and in vascular development (By similarity). Mediates up-regulation of pro-inflammatory cytokines, such as MCP-1/CCL2 and IL6, triggered by coagulation factor Xa (F10) in cardiac fibroblasts and umbilical vein endothelial cells (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; MMP-1 promotes VEGFR2 expression and proliferation of endothelial cells through stimulation of PAR-1 and activation of NF-kappaB, [RefSeq, PubMed]; PAR1 and PAR2 regulate endothelial NO synthase phosphorylation and activity through G(12/13) and G(q), delineating the signaling pathways by which the proteases act on protease-activated receptors to modulate endothelial functions., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015057 thrombin-activated receptor activity;GO:0031681 G-protein beta-subunit binding;GO:0004930 G protein-coupled receptor activity;GO:0001965 G-protein alpha-subunit binding", "go_cellular_component": "GO:0031094 platelet dense tubular network;GO:0005886 plasma membrane;GO:0031594 neuromuscular junction;GO:0045211 postsynaptic membrane;GO:0005901 caveola", "go_biological_process": "GO:0007529 establishment of synaptic specificity at neuromuscular junction;GO:0032651 regulation of interleukin-1 beta production;GO:1900134 negative regulation of renin secretion into blood stream;GO:0006954 inflammatory response;GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A7YY44-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A7Z019-1", "uniprot_id": "SMCA4_BOVIN", "mass": 180679.0, "length": 1606, "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "gene_name": "SMARCA4", "organism": "Bovine", "refseq_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "refseq_ac": "NP_001099084", "gene_names_uniprotkb": "SMARCA4; BAF190A; BRG1; SNF2B; SNF2L4", "gene_names_refseq": "BAF190A; BRG1; SMARCA4", "protein_names_uniprotkb": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; 3.6.4.-; BAF190A; BRG1-associated factor 190A; Protein brahma homolog 1; SMARCA4; SNF2-beta; Transcription activator BRG1", "protein_names_refseq": "ATP-dependent helicase SMARCA4; BRG1-associated factor 190A; SNF2-beta; SWI/SNF related transcriptional activator; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; WI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; protein brahma homolog 1; transcription activator BRG1", "tax_id": 9913, "disease": "", "pathway": " (bta:414274); (R-BTA-1266695); (R-BTA-201722); (R-BTA-3214858); (R-BTA-3247509); (R-BTA-8939243); (R-BTA-9764725); (R-BTA-9933937); (R-BTA-9933939); (R-BTA-9933946); (R-BTA-9933947); (R-BTA-9934037)", "pathway_count": 12, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "ATPase involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating the calcium-dependent release of a repressor complex and the recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by SMARCA4-dependent recruitment of a phospho-RB1-HDAC repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves the release of HDAC1 and recruitment of CREBBP. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development, a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. SMARCA4/BAF190A may promote neural stem cell self-renewal/proliferation by enhancing Notch-dependent proliferative signals, while concurrently making the neural stem cell insensitive to SHH-dependent differentiating cues (By similarity). Acts as a corepressor of ZEB1 to regulate E-cadherin transcription and is required for induction of epithelial-mesenchymal transition (EMT) by ZEB1. Binds via DLX1 to enhancers located in the intergenic region between DLX5 and DLX6 and this binding is stabilized by the long non-coding RNA (lncRNA) Evf2 (By similarity). Binds to RNA in a promiscuous manner (By similarity). Binding to RNAs including lncRNA Evf2 leads to inhibition of SMARCA4 ATPase and chromatin remodeling activities (By similarity). In brown adipose tissue, involved in the regulation of thermogenic genes expression (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;2.1.1.320;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;2.7.11.22;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0016514 SWI/SNF complex;GO:0071564 npBAF complex;GO:0071565 nBAF complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A7Z019-1", "record_type": "protein" }, { "uniprot_canonical_ac": "C1ITJ8-1", "uniprot_id": "HMR1_BOVIN", "mass": 38894.0, "length": 336, "protein_name": "Major histocompatibility complex class I-related protein 1", "gene_name": "MR1", "organism": "Bovine", "refseq_name": "major histocompatibility complex class I-related protein 1 precursor", "refseq_ac": "NP_001177227", "gene_names_uniprotkb": "MR1", "gene_names_refseq": "MR1", "protein_names_uniprotkb": "Major histocompatibility complex class I-related protein 1; Class I histocompatibility antigen-like protein; MHC class I-related protein 1", "protein_names_refseq": "MHC class I-related gene protein; MHC class I-related protein 1; MHC class I-related protein; class I histocompatibility antigen-like protein; major histocompatibility complex class I-related gene protein; major histocompatibility complex class I-related protein 1 precursor; major histocompatibility complex class I-related protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:506206)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "19393038;19416870;23613577", "class_list": "", "function": "Antigen-presenting molecule specialized in displaying microbial pyrimidine-based metabolites to alpha-beta T cell receptors (TCR) on innate-type mucosal-associated invariant T (MAIT) cells. In complex with B2M preferentially presents riboflavin-derived metabolites to semi-invariant TCRs on MAIT cells, guiding immune surveillance of the microbial metabolome at mucosal epithelial barriers (By similarity). Signature pyrimidine-based microbial antigens are generated via non-enzymatic condensation of metabolite intermediates of the riboflavin pathway with by-products arising from other metabolic pathways such as glycolysis. Typical potent antigenic metabolites are 5-(2-oxoethylideneamino)-6-D-ribitylaminouracil (5-OE-RU) and 5-(2-oxopropylideneamino)-6-D-ribitylaminouracil (5-OP-RU), products of condensation of 5-amino-6-D-ribityaminouracil (5-A-RU) with glyoxal or methylglyoxal by-products, respectively (By similarity). May present microbial antigens to various MAIT cell subsets, providing for unique recognition of diverse microbes, including pathogens that do not synthesize riboflavin. Upon antigen recognition, elicits rapid innate-type MAIT cell activation to eliminate pathogenic microbes by directly killing infected cells (By similarity). During T cell development, drives thymic selection and post-thymic terminal differentiation of MAIT cells in a process dependent on commensal microflora (By similarity). Acts as an immune sensor of cancer cell metabolome. May present a tumor-specific or -associated metabolite essential for cancer cell survival to a pan-cancer TCR on a non-MAIT CD8-positive T cell clone, triggering T cell-mediated killing of a wide range of cancer cell types (By similarity). May present tumor-enriched pyridoxal and pyridoxal 5'-phosphate antigens, enabling preferential recognition of cancer cells (By similarity). Presents nucleobase carbonyl adducts generated during oxidative stress. Captures M3Ade, a nucleobase adduct composed of one adenine modified by a malondialdehyde trimer, for recognition by MR1-restricted T cell clones expressing a polyclonal TCR repertoire (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "F1MVL8", "ec_number_list": "", "go_molecular_function": "GO:0030881 beta-2-microglobulin binding;GO:0042608 T cell receptor binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0045087 innate immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0002474 antigen processing and presentation of peptide antigen via MHC class I", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "C1ITJ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1B732-1", "uniprot_id": "E1B732_BOVIN", "mass": 26824.0, "length": 239, "protein_name": "Homeobox protein Nkx-3.1", "gene_name": "NKX3-1", "organism": "Bovine", "refseq_name": "homeobox protein Nkx-3.1 isoform X1", "refseq_ac": "XP_005210335", "gene_names_uniprotkb": "NKX3-1", "gene_names_refseq": "NKX3-1", "protein_names_uniprotkb": "Homeobox protein Nkx-3.1; Homeobox protein NK-3 homolog A", "protein_names_refseq": "homeobox protein Nkx-3.1 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0042826 histone deacetylase binding;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0090734 site of DNA damage", "go_biological_process": "GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007507 heart development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1B732-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BB50-1", "uniprot_id": "CDK12_BOVIN", "mass": 140642.0, "length": 1264, "protein_name": "Cyclin-dependent kinase 12", "gene_name": "CDK12", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CDK12", "gene_names_refseq": "", "protein_names_uniprotkb": "Cyclin-dependent kinase 12; 2.7.11.22; 2.7.11.23; Cell division protein kinase 12", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 38, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex;GO:0008024 cyclin/CDK positive transcription elongation factor complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0008380 RNA splicing;GO:0032968 positive regulation of transcription elongation by RNA polymerase II;GO:0043405 regulation of MAP kinase activity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BB50-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BDG5-1", "uniprot_id": "E1BDG5_BOVIN", "mass": 42423.0, "length": 380, "protein_name": "Protein Wnt", "gene_name": "WNT5A", "organism": "Bovine", "refseq_name": "protein Wnt-5a", "refseq_ac": "NP_001192900", "gene_names_uniprotkb": "WNT5A", "gene_names_refseq": "WNT5A", "protein_names_uniprotkb": "Protein Wnt", "protein_names_refseq": "protein Wnt-5a; wingless-type MMTV integration site family, member 5A", "tax_id": 9913, "disease": "", "pathway": " (bta:530005); (R-BTA-201681); (R-BTA-3238698); (R-BTA-4086398); (R-BTA-4086400); (R-BTA-4608870); (R-BTA-5099900); (R-BTA-5140745); (R-BTA-8856825); (R-BTA-8856828)", "pathway_count": 10, "publication_count": 1, "publication_id_list": "25600632", "class_list": "", "function": "Ligand for members of the frizzled family of seven transmembrane receptors., [UniProtKB, UniProtKB]; WNT5A is a negative regulator of FSH-stimulated granulosa cell steroidogenesis in cattle., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005109 frizzled binding;GO:0019904 protein domain specific binding;GO:0005125 cytokine activity;GO:0005115 receptor tyrosine kinase-like orphan receptor binding;GO:1902379 chemoattractant activity involved in axon guidance", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005615 extracellular space;GO:0009986 cell surface;GO:0031012 extracellular matrix;GO:0098794 postsynapse", "go_biological_process": "GO:0043032 positive regulation of macrophage activation;GO:0048806 genitalia development;GO:0060760 positive regulation of response to cytokine stimulus;GO:0010742 macrophage derived foam cell differentiation;GO:0048022 negative regulation of melanin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E1BDG5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BE57-1", "uniprot_id": "E1BE57_BOVIN", "mass": 85582.0, "length": 780, "protein_name": "Protein smoothened", "gene_name": "SMO", "organism": "Bovine", "refseq_name": "protein smoothened precursor", "refseq_ac": "NP_001179149", "gene_names_uniprotkb": "SMO", "gene_names_refseq": "SMO", "protein_names_uniprotkb": "Protein smoothened", "protein_names_refseq": "protein smoothened precursor; smoothened homolog; smoothened, frizzled family receptor; smoothened, seven transmembrane spanning receptor", "tax_id": 9913, "disease": "", "pathway": " (bta:539308); (R-BTA-5610787); (R-BTA-5620922); (R-BTA-5632684); (R-BTA-5635838)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "26225956", "class_list": "", "function": "G protein-coupled receptor which associates with the patched protein (PTCH) to transduce hedgehog protein signaling. Binding of sonic hedgehog (SHH) to its receptor patched prevents inhibition of smoothened (SMO) by patched. When active, SMO binds to and sequesters protein kinase A catalytic subunit PRKACA at the cell membrane, preventing PRKACA-mediated phosphorylation of GLI transcription factors which releases the GLI proteins from PRKACA-mediated inhibition and allows for transcriptional activation of hedgehog pathway target genes. Required for the accumulation of KIF7, GLI2 and GLI3 in the cilia. Interacts with DLG5 at the ciliary base to induce the accumulation of KIF7 and GLI2 at the ciliary tip for GLI2 activation., [UniProtKB, UniProtKB]; Variations in the SMO gene could affect body size traits of Qinchuan cattle. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0034236 protein kinase A catalytic subunit binding;GO:0008142 oxysterol binding;GO:0004930 G protein-coupled receptor activity;GO:0004862 cAMP-dependent protein kinase inhibitor activity;GO:0005113 patched binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005929 cilium;GO:0030425 dendrite", "go_biological_process": "GO:0060242 contact inhibition;GO:0003140 determination of left/right asymmetry in lateral mesoderm;GO:0021513 spinal cord dorsal/ventral patterning;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E1BE57-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BE92-1", "uniprot_id": "E1BE92_BOVIN", "mass": 52150.0, "length": 466, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "SMAD2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SMAD2", "gene_names_refseq": "", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1181150); (R-BTA-1502540); (R-BTA-2173788); (R-BTA-2173789); (R-BTA-2173795); (R-BTA-2173796); (R-BTA-5689880); (R-BTA-9617828)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070410 co-SMAD binding;GO:0003682 chromatin binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0000785 chromatin", "go_biological_process": "GO:0017015 regulation of transforming growth factor beta receptor signaling pathway;GO:0003140 determination of left/right asymmetry in lateral mesoderm;GO:0006351 DNA-templated transcription;GO:0010629 negative regulation of gene expression;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BE92-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BEN9-1", "uniprot_id": "E1BEN9_BOVIN", "mass": 41039.0, "length": 370, "protein_name": "Protein Wnt", "gene_name": "WNT1", "organism": "Bovine", "refseq_name": "proto-oncogene Wnt-1 precursor", "refseq_ac": "NP_001107663", "gene_names_uniprotkb": "WNT1", "gene_names_refseq": "WNT1", "protein_names_uniprotkb": "Protein Wnt", "protein_names_refseq": "murine mammary tumor virus integration site; proto-oncogene Wnt-1 precursor; wingless-type MMTV integration site family, member 1", "tax_id": 9913, "disease": "", "pathway": " (bta:540662); (R-BTA-201681); (R-BTA-3238698); (R-BTA-4086400); (R-BTA-4641262)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "12915124", "class_list": "", "function": "Data indicate that Wnt-1 protein is present in postdevelopmental endothelial cells where it associates with cytoskeletal elements and may retain function as a tissue polarity gene., [RefSeq, PubMed]; Ligand for members of the frizzled family of seven transmembrane receptors., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005109 frizzled binding;GO:0019904 protein domain specific binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0009986 cell surface", "go_biological_process": "GO:0000578 embryonic axis specification;GO:0021551 central nervous system morphogenesis;GO:0009611 response to wounding;GO:0045747 positive regulation of Notch signaling pathway;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E1BEN9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BFR5-1", "uniprot_id": "GWL_BOVIN", "mass": 98072.0, "length": 883, "protein_name": "Serine/threonine-protein kinase greatwall", "gene_name": "MASTL", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MASTL; GWL; GW", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein kinase greatwall; 2.7.11.1; GWL; GW; MAST-L; Microtubule-associated serine/threonine-protein kinase-like", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance (By similarity). Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively (By similarity). ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0051721 protein phosphatase 2A binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0015630 microtubule cytoskeleton;GO:0032154 cleavage furrow", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0035556 intracellular signal transduction;GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BFR5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BGD5-1", "uniprot_id": "E1BGD5_BOVIN", "mass": 39598.0, "length": 350, "protein_name": "Mitochondrial ubiquitin ligase activator of NFKB 1", "gene_name": "MUL1", "organism": "Bovine", "refseq_name": "mitochondrial ubiquitin ligase activator of NFKB 1", "refseq_ac": "NP_001179111", "gene_names_uniprotkb": "MUL1", "gene_names_refseq": "MUL1", "protein_names_uniprotkb": "Mitochondrial ubiquitin ligase activator of NFKB 1; 2.3.2.27; E3 ubiquitin-protein ligase MUL1; Protein Hades; RING-type E3 ubiquitin transferase NFKB 1", "protein_names_refseq": "mitochondrial E3 ubiquitin ligase 1; mitochondrial ubiquitin ligase activator of NFKB 1", "tax_id": 9913, "disease": "", "pathway": " (bta:508406); (R-BTA-5689880); (R-BTA-8951664); (R-BTA-9755511)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.2.1.8;2.3.2.27;3.4.19.12;3.4.24.56;3.6.5.-;3.1.1.29", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0061630 ubiquitin protein ligase activity;GO:0002039 p53 binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005777 peroxisome;GO:0030424 axon;GO:0043025 neuronal cell body;GO:0140596 TOM complex", "go_biological_process": "GO:0071360 cellular response to exogenous dsRNA;GO:1903861 positive regulation of dendrite extension;GO:0050689 negative regulation of defense response to virus by host;GO:0051881 regulation of mitochondrial membrane potential;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BGD5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BGZ6-1", "uniprot_id": "E1BGZ6_BOVIN", "mass": 49323.0, "length": 447, "protein_name": "T-box transcription factor TBX20", "gene_name": "TBX20", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TBX20", "gene_names_refseq": "", "protein_names_uniprotkb": "T-box transcription factor TBX20", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a transcriptional activator and repressor required for cardiac development and may have key roles in the maintenance of functional and structural phenotypes in adult heart., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0001708 cell fate specification;GO:0036302 atrioventricular canal development;GO:0060577 pulmonary vein morphogenesis;GO:0003175 tricuspid valve development;GO:0036306 embryonic heart tube elongation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BGZ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BHF2-1", "uniprot_id": "E1BHF2_BOVIN", "mass": 55382.0, "length": 490, "protein_name": "Multifunctional fusion protein", "gene_name": "KATNAL1", "organism": "Bovine", "refseq_name": "katanin p60 ATPase-containing subunit A-like 1", "refseq_ac": "NP_001179847", "gene_names_uniprotkb": "KATNAL1; KATNA1", "gene_names_refseq": "KATNAL1", "protein_names_uniprotkb": "Multifunctional fusion protein; p60 katanin-like 1; p60 katanin", "protein_names_refseq": "katanin p60 ATPase-containing subunit A-like 1; katanin p60 subunit A-like 1-AS protein", "tax_id": 9913, "disease": "", "pathway": " (bta:537739)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "24990491", "class_list": "", "function": "Alternative promoter polymorphisms produce splice variants of KATNAL1, which causes sperm deformity, [RefSeq, PubMed]; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth., [UniProtKB, HAMAP, UniProtKB]; Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays. Has microtubule-severing activity in vitro., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "W0GI54", "ec_number_list": "", "go_molecular_function": "GO:0008568 microtubule severing ATPase activity;GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0042802 identical protein binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005874 microtubule;GO:0030496 midbody", "go_biological_process": "GO:0051013 microtubule severing;GO:0007283 spermatogenesis;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E1BHF2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BHM6-1", "uniprot_id": "E1BHM6_BOVIN", "mass": 206279.0, "length": 1801, "protein_name": "Sodium channel protein", "gene_name": "SCN11A", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SCN11A", "gene_names_refseq": "", "protein_names_uniprotkb": "Sodium channel protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5576892)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient., [UniProtKB, UniProtKB]; Sodium channel mediating the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Involved in membrane depolarization during action potential in nociceptors which function as key relay stations for the electrical transmission of pain signals from the periphery to the central nervous system. Also involved in rapid BDNF-evoked neuronal depolarization., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.-.-", "go_molecular_function": "GO:0005248 voltage-gated sodium channel activity", "go_cellular_component": "GO:0043025 neuronal cell body;GO:0044295 axonal growth cone;GO:0044299 C-fiber;GO:0001518 voltage-gated sodium channel complex", "go_biological_process": "GO:0060538 skeletal muscle organ development;GO:0070417 cellular response to cold;GO:0061368 behavioral response to formalin induced pain;GO:0060004 reflex;GO:0007409 axonogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BHM6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BHV1-1", "uniprot_id": "E1BHV1_BOVIN", "mass": 565151.0, "length": 4974, "protein_name": "Ryanodine receptor 2", "gene_name": "RYR2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RYR2", "gene_names_refseq": "", "protein_names_uniprotkb": "Ryanodine receptor 2; Cardiac muscle ryanodine receptor-calcium release channel; Cardiac muscle ryanodine receptor; Type 2 ryanodine receptor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2672351); (R-BTA-5578775)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cytosolic calcium-activated calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytosol and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) cytosolic levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1", "go_molecular_function": "GO:0034236 protein kinase A catalytic subunit binding;GO:0005516 calmodulin binding;GO:0042802 identical protein binding;GO:0005509 calcium ion binding;GO:0034237 protein kinase A regulatory subunit binding", "go_cellular_component": "GO:0005790 smooth endoplasmic reticulum;GO:0042383 sarcolemma;GO:0030018 Z disc;GO:0034704 calcium channel complex;GO:0033017 sarcoplasmic reticulum membrane", "go_biological_process": "GO:0051775 response to redox state;GO:0001666 response to hypoxia;GO:0006874 intracellular calcium ion homeostasis;GO:0014850 response to muscle activity;GO:0035994 response to muscle stretch", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BHV1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BHW6-1", "uniprot_id": "E1BHW6_BOVIN", "mass": 61529.0, "length": 549, "protein_name": "Solute carrier family 22 member 2", "gene_name": "SLC22A2", "organism": "Bovine", "refseq_name": "solute carrier family 22 member 2 isoform X1", "refseq_ac": "XP_002690417", "gene_names_uniprotkb": "SLC22A2", "gene_names_refseq": "SLC22A2", "protein_names_uniprotkb": "Solute carrier family 22 member 2", "protein_names_refseq": "solute carrier family 22 member 2 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:521027); (R-BTA-112311); (R-BTA-181430); (R-BTA-2161517); (R-BTA-442660); (R-BTA-549127)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015651 quaternary ammonium group transmembrane transporter activity;GO:0042910 xenobiotic transmembrane transporter activity;GO:0019534 toxin transmembrane transporter activity;GO:0015562 efflux transmembrane transporter activity;GO:0005275 amine transmembrane transporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0098793 presynapse", "go_biological_process": "GO:0015870 acetylcholine transport;GO:0015695 organic cation transport;GO:0006811 monoatomic ion transport;GO:0097638 L-arginine import across plasma membrane;GO:0051615 histamine uptake", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BHW6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BI59-1", "uniprot_id": "E1BI59_BOVIN", "mass": 42824.0, "length": 413, "protein_name": "GATA binding protein 1", "gene_name": "GATA1", "organism": "Bovine", "refseq_name": "erythroid transcription factor", "refseq_ac": "NP_001193169", "gene_names_uniprotkb": "GATA1", "gene_names_refseq": "GATA1", "protein_names_uniprotkb": "GATA binding protein 1", "protein_names_refseq": "erythroid transcription factor", "tax_id": 9913, "disease": "", "pathway": " (bta:516066); (R-BTA-8936459); (R-BTA-8939236); (R-BTA-983231)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0031490 chromatin DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0017053 transcription repressor complex;GO:0032993 protein-DNA complex", "go_biological_process": "GO:0030219 megakaryocyte differentiation;GO:0010724 regulation of definitive erythrocyte differentiation;GO:0030221 basophil differentiation;GO:0035854 eosinophil fate commitment;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BI59-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BIP0-1", "uniprot_id": "E1BIP0_BOVIN", "mass": 35378.0, "length": 316, "protein_name": "Tumor necrosis factor ligand superfamily member", "gene_name": "TNFSF11", "organism": "Bovine", "refseq_name": "tumor necrosis factor ligand superfamily member 11", "refseq_ac": "NP_001192699", "gene_names_uniprotkb": "TNFSF11", "gene_names_refseq": "TNFSF11", "protein_names_uniprotkb": "Tumor necrosis factor ligand superfamily member", "protein_names_refseq": "tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand superfamily member 11; tumor necrosis factor superfamily member 11", "tax_id": 9913, "disease": "", "pathway": " (bta:513836); (R-BTA-5668541); (R-BTA-5669034); (R-BTA-5676594); (R-BTA-9856649)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0005125 cytokine activity;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0030316 osteoclast differentiation;GO:0071812 positive regulation of fever generation by positive regulation of prostaglandin secretion;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006955 immune response;GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BIP0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BJ34-1", "uniprot_id": "E1BJ34_BOVIN", "mass": 39831.0, "length": 346, "protein_name": "Nodal growth differentiation factor", "gene_name": "NODAL", "organism": "Bovine", "refseq_name": "nodal homolog precursor", "refseq_ac": "NP_001192911", "gene_names_uniprotkb": "NODAL", "gene_names_refseq": "NODAL", "protein_names_uniprotkb": "Nodal growth differentiation factor", "protein_names_refseq": "nodal homolog precursor; nodal homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:530748)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23052837", "class_list": "", "function": "Essential for mesoderm formation and axial patterning during embryonic development., [UniProtKB, UniProtKB]; Report the presence of Nodal in the bovine reproductive tract and suggest it may be a possible marker of the fertility process., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0008083 growth factor activity;GO:0070698 type I activin receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0022409 positive regulation of cell-cell adhesion;GO:0003140 determination of left/right asymmetry in lateral mesoderm;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0070374 positive regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E1BJ34-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BJP4-1", "uniprot_id": "E1BJP4_BOVIN", "mass": 51629.0, "length": 509, "protein_name": "Serum response factor", "gene_name": "SRF", "organism": "Bovine", "refseq_name": "serum response factor", "refseq_ac": "NP_001192945", "gene_names_uniprotkb": "SRF", "gene_names_refseq": "SRF", "protein_names_uniprotkb": "Serum response factor", "protein_names_refseq": "serum response factor (c-fos serum response element-binding transcription factor); serum response factor", "tax_id": 9913, "disease": "", "pathway": " (bta:533039); (R-BTA-5663220)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. Required for cardiac differentiation and maturation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0010736 serum response element binding;GO:0042803 protein homodimerization activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0031490 chromatin DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0060379 cardiac muscle cell myoblast differentiation;GO:0001701 in utero embryonic development;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BJP4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BKC3-1", "uniprot_id": "E1BKC3_BOVIN", "mass": 88203.0, "length": 780, "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "organism": "Bovine", "refseq_name": "tumor necrosis factor alpha-induced protein 3", "refseq_ac": "NP_001179099", "gene_names_uniprotkb": "TNFAIP3", "gene_names_refseq": "TNFAIP3", "protein_names_uniprotkb": "Tumor necrosis factor alpha-induced protein 3; 3.4.19.12; Putative DNA-binding protein A20; Zinc finger protein A20", "protein_names_refseq": "tumor necrosis factor alpha-induced protein 3; tumor necrosis factor, alpha-induced protein 3", "tax_id": 9913, "disease": "", "pathway": " (bta:508105)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "26809100", "class_list": "", "function": "Data show the characterization and deduced amino acid sequence analysis for A20 gene which expression increases in MDBK cells infected by BVDV-1. Also, regulatory regions for NF-kappaB and Sp-1 additionally to an ARE element for mRNA stability were detected, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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"total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.11.1.8;1.6.99.1;1.6.3.1;1.14.13.225", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0020037 heme binding;GO:0016174 NAD(P)H oxidase H2O2-forming activity;GO:0004601 peroxidase activity;GO:0016175 superoxide-generating NAD(P)H oxidase activity", "go_cellular_component": "GO:0043020 NADPH oxidase complex;GO:0005886 plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006952 defense response;GO:0006979 response to oxidative stress;GO:0042446 hormone biosynthetic process;GO:0042744 hydrogen peroxide catabolic process;GO:0006590 thyroid hormone generation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BMS3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BN18-1", "uniprot_id": "E1BN18_BOVIN", "mass": 77531.0, "length": 722, "protein_name": "Delta-like protein", "gene_name": "DLL1", "organism": "Bovine", "refseq_name": "delta-like protein 1", "refseq_ac": "XP_010807105", "gene_names_uniprotkb": "DLL1", "gene_names_refseq": "DLL1", "protein_names_uniprotkb": "Delta-like protein", "protein_names_refseq": "delta-like protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:788775)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Putative Notch ligand involved in the mediation of Notch signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005112 Notch binding;GO:0030957 Tat protein binding;GO:0097110 scaffold protein binding;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005912 adherens junction;GO:0045121 membrane raft;GO:0016324 apical plasma membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0021688 cerebellar molecular layer formation;GO:0021693 cerebellar Purkinje cell layer structural organization;GO:0032693 negative regulation of interleukin-10 production;GO:0045605 negative regulation of epidermal cell differentiation;GO:0046331 lateral inhibition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BN18-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BNP2-1", "uniprot_id": "E1BNP2_BOVIN", "mass": 33981.0, "length": 309, "protein_name": "Homeobox A11", "gene_name": "HOXA11", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HOXA11", "gene_names_refseq": "", "protein_names_uniprotkb": "Homeobox A11", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex;GO:0032993 protein-DNA complex;GO:0032991 protein-containing complex", "go_biological_process": "GO:0007501 mesodermal cell fate specification;GO:0010720 positive regulation of cell development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0001501 skeletal system development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BNP2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BP59-1", "uniprot_id": "E1BP59_BOVIN", "mass": 94122.0, "length": 838, "protein_name": "histone acetyltransferase", "gene_name": "KAT2A", "organism": "Bovine", "refseq_name": "histone acetyltransferase KAT2A isoform X1", "refseq_ac": "XP_024836652", "gene_names_uniprotkb": "KAT2A", "gene_names_refseq": "KAT2A", "protein_names_uniprotkb": "histone acetyltransferase; 2.3.1.48", "protein_names_refseq": "histone acetyltransferase KAT2A isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:514420); (R-BTA-350054); (R-BTA-5250924); (R-BTA-5689880); (R-BTA-8941856); (R-BTA-9772755)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 6, "predicted_n_glycosites": 0, "predicted_o_glycosites": 6, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.48;3.4.19.12;2.7.10.2;2.7.7.6;3.6.4.13", "go_molecular_function": "GO:0043997 histone H4K12 acetyltransferase activity;GO:0106078 histone succinyltransferase activity;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0042826 histone deacetylase binding", "go_cellular_component": "GO:0033276 transcription factor TFTC complex;GO:0005813 centrosome;GO:0000124 SAGA complex;GO:0072686 mitotic spindle;GO:0045252 oxoglutarate dehydrogenase complex", "go_biological_process": "GO:1903010 regulation of bone development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BP59-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BPC3-1", "uniprot_id": "E1BPC3_BOVIN", "mass": 143739.0, "length": 1251, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "ATP8B1", "organism": "Bovine", "refseq_name": "phospholipid-transporting ATPase IC", "refseq_ac": "NP_001179768", "gene_names_uniprotkb": "ATP8B1", "gene_names_refseq": "ATP8B1", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "ATPase, class I, type 8B, member 1; phospholipid-transporting ATPase IC", "tax_id": 9913, "disease": "", "pathway": " (bta:541187); (R-BTA-936837)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "7.6.2.1", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0090554 phosphatidylcholine floppase activity;GO:0090556 phosphatidylserine floppase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0016324 apical plasma membrane;GO:0005802 trans-Golgi network;GO:0032420 stereocilium", "go_biological_process": "GO:0015721 bile acid and bile salt transport;GO:0045892 negative regulation of DNA-templated transcription;GO:0045332 phospholipid translocation;GO:0007605 sensory perception of sound;GO:0006855 xenobiotic transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BPC3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BPW0-1", "uniprot_id": "ENTP5_BOVIN", "mass": 47888.0, "length": 432, "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 5", "gene_name": "ENTPD5", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ENTPD5", "gene_names_refseq": "", "protein_names_uniprotkb": "Ectonucleoside triphosphate diphosphohydrolase 5; 3.6.1.6; GDPase ENTPD5; Guanosine-diphosphatase ENTPD5; NTPDase 5; UDPase ENTPD5; Uridine-diphosphatase ENTPD5", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hydrolyzes nucleoside diphosphates with a preference for GDP, IDP and UDP compared to ADP and CDP (By similarity). In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases. UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP-glucose. Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose. Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.1.5;3.6.1.6;3.6.1.64;3.6.1.62;3.6.1.16;3.6.1.53;3.1.3.1;3.9.1.1", "go_molecular_function": "GO:0004382 GDP phosphatase activity;GO:0043262 ADP phosphatase activity;GO:0045134 UDP phosphatase activity;GO:1990003 IDP phosphatase activity;GO:0036384 CDP phosphatase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006256 UDP catabolic process;GO:0006487 protein N-linked glycosylation;GO:0006011 UDP-alpha-D-glucose metabolic process;GO:0051084 'de novo' post-translational protein folding", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BPW0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BPX4-1", "uniprot_id": "MCM8_BOVIN", "mass": 90768.0, "length": 816, "protein_name": "DNA helicase MCM8", "gene_name": "MCM8", "organism": "Bovine", "refseq_name": "DNA helicase MCM8", "refseq_ac": "NP_001179965", "gene_names_uniprotkb": "MCM8", "gene_names_refseq": "MCM8", "protein_names_uniprotkb": "DNA helicase MCM8; 5.6.2.4; DNA 3'-5' helicase MCM8; Minichromosome maintenance 8", "protein_names_refseq": "DNA 3'-5' helicase MCM8; DNA helicase MCM8; minichromosome maintenance complex component 8", "tax_id": 9913, "disease": "", "pathway": " (bta:507507); (R-BTA-176187); (R-BTA-68689); (R-BTA-68949); (R-BTA-68962)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Component of the MCM8-MCM9 complex, which is involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross-links (ICLs) by homologous recombination (HR). The MCM8-MCM9 complex is a 3'-5' DNA helicase and single-stranded (ss)DNA-stimulated ATPase which binds ssDNA in the presence of nucleoside triphosphates. Required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting the complex nuclease activity. Indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs and ICLs, probably by regulating the localization of the MNR complex. The MCM8-MCM9 complex is dispensable for DNA replication and S phase progression. However, may play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex (pre-RC) during G(1) phase by recruiting CDC6 to the origin recognition complex (ORC). Probably by regulating HR, plays a key role during gametogenesis. Stabilizes MCM9 protein., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;2.7.7.-;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53;2.7.11.22", "go_molecular_function": "GO:0043138 3'-5' DNA helicase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0097362 MCM8-MCM9 complex;GO:0042555 MCM complex", "go_biological_process": "GO:0006260 DNA replication;GO:0006974 DNA damage response;GO:0000724 double-strand break repair via homologous recombination;GO:0007292 female gamete generation;GO:0048232 male gamete generation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "E1BPX4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1BQ32-1", "uniprot_id": "E1BQ32_BOVIN", "mass": 40598.0, "length": 377, "protein_name": "Adapter molecule crk", "gene_name": "CRK", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CRK", "gene_names_refseq": "", "protein_names_uniprotkb": "Adapter molecule crk; Proto-oncogene c-Crk; p38", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-170984); (R-BTA-186763); (R-BTA-2029482); (R-BTA-372708); (R-BTA-4420097); (R-BTA-8849471); (R-BTA-8875555); (R-BTA-8875656); (R-BTA-912631)", "pathway_count": 9, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0017124 SH3 domain binding;GO:0031625 ubiquitin protein ligase binding;GO:0042169 SH2 domain binding;GO:0030971 receptor tyrosine kinase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton;GO:0031594 neuromuscular junction", "go_biological_process": "GO:0008283 cell population proliferation;GO:0016477 cell migration;GO:0032956 regulation of actin cytoskeleton organization;GO:0048013 ephrin receptor signaling pathway;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "E1BQ32-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MAX1-1", "uniprot_id": "F1MAX1_BOVIN", "mass": 73155.0, "length": 667, "protein_name": "Transporter", "gene_name": "SLC6A3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC6A3", "gene_names_refseq": "", "protein_names_uniprotkb": "Transporter", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-379397); (R-BTA-379398); (R-BTA-379401); (R-BTA-442660)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mediates sodium- and chloride-dependent transport of dopamine. Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0046872 metal ion binding;GO:0005330 dopamine:sodium symporter activity;GO:0035240 dopamine binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0043025 neuronal cell body;GO:0043679 axon terminus;GO:0016600 flotillin complex", "go_biological_process": "GO:1990384 hyaloid vascular plexus regression;GO:0006865 amino acid transport;GO:0035725 sodium ion transmembrane transport;GO:0001504 neurotransmitter uptake", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MAX1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MBH4-1", "uniprot_id": "F1MBH4_BOVIN", "mass": 45657.0, "length": 437, "protein_name": "Forkhead box F1", "gene_name": "FOXF1", "organism": "Bovine", "refseq_name": "forkhead box protein F1", "refseq_ac": "XP_002694800", "gene_names_uniprotkb": "FOXF1", "gene_names_refseq": "FOXF1", "protein_names_uniprotkb": "Forkhead box F1", "protein_names_refseq": "forkhead box protein F1", "tax_id": 9913, "disease": "", "pathway": " (bta:524813)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0001701 in utero embryonic development;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007494 midgut development;GO:0009887 animal organ morphogenesis;GO:0031016 pancreas development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MBH4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MBL5-1", "uniprot_id": "F1MBL5_BOVIN", "mass": 56240.0, "length": 534, "protein_name": "SRY-box transcription factor 8", "gene_name": "SOX8", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SOX8", "gene_names_refseq": "", "protein_names_uniprotkb": "SRY-box transcription factor 8", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:530317)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0048484 enteric nervous system development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007165 signal transduction;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MBL5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MCS4-1", "uniprot_id": "F1MCS4_BOVIN", "mass": 20485.0, "length": 179, "protein_name": "Interleukin family protein", "gene_name": "IL10", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IL10", "gene_names_refseq": "", "protein_names_uniprotkb": "Interleukin family protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Immune regulatory cytokine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0045063 T-helper 1 cell differentiation;GO:0051045 negative regulation of membrane protein ectodomain proteolysis;GO:1903034 regulation of response to wounding;GO:1903672 positive regulation of sprouting angiogenesis;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MCS4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MD26-1", "uniprot_id": "F1MD26_BOVIN", "mass": 67372.0, "length": 633, "protein_name": "HNF1 homeobox A", "gene_name": "HNF1A", "organism": "Bovine", "refseq_name": "hepatocyte nuclear factor 1-alpha", "refseq_ac": "NP_001179453", "gene_names_uniprotkb": "HNF1A", "gene_names_refseq": "HNF-1a; HNF1A", "protein_names_uniprotkb": "HNF1 homeobox A", "protein_names_refseq": "hepatocyte nuclear factor 1 alpha; hepatocyte nuclear factor 1-alpha", "tax_id": 9913, "disease": "", "pathway": " (bta:503578)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, 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DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex;GO:0001750 photoreceptor outer segment;GO:0045120 pronucleus", "go_biological_process": "GO:0035623 renal D-glucose absorption;GO:0001889 liver development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0042593 glucose homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MD26-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MD46-1", "uniprot_id": "F1MD46_BOVIN", "mass": 106171.0, "length": 928, "protein_name": "Retinoblastoma-associated protein", "gene_name": "RB1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RB1", "gene_names_refseq": "", "protein_names_uniprotkb": "Retinoblastoma-associated protein; pRb", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-113501); (R-BTA-174178); (R-BTA-2299718); (R-BTA-69200); (R-BTA-69202); (R-BTA-69231); (R-BTA-69656); (R-BTA-9841922)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, 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differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MD46-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MDU7-1", "uniprot_id": "F1MDU7_BOVIN", "mass": 174446.0, "length": 1532, "protein_name": "DNA topoisomerase 2", "gene_name": "TOP2A", "organism": "Bovine", "refseq_name": "DNA topoisomerase 2-alpha isoform X1", "refseq_ac": "XP_005220838", "gene_names_uniprotkb": "TOP2A", "gene_names_refseq": "TOP2A", "protein_names_uniprotkb": "DNA topoisomerase 2; 5.6.2.2", "protein_names_refseq": "DNA topoisomerase 2-alpha isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:787696); (R-BTA-4615885)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "30573663", "class_list": "", "function": "Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. May play a role in regulating the period length of BMAL1 transcriptional oscillation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.2.2", "go_molecular_function": "GO:0008301 DNA binding, bending;GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity;GO:0000287 magnesium ion binding;GO:0003682 chromatin binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000775 chromosome, centromeric region", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0043065 positive regulation of apoptotic process;GO:0006974 DNA damage response;GO:0030263 apoptotic chromosome condensation;GO:0042752 regulation of circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MDU7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MFP2-1", "uniprot_id": "F1MFP2_BOVIN", "mass": 43610.0, "length": 401, "protein_name": "Hedgehog protein", "gene_name": "DHH", "organism": "Bovine", "refseq_name": "desert hedgehog protein", "refseq_ac": "XP_024848224", "gene_names_uniprotkb": "DHH", "gene_names_refseq": "DHH", "protein_names_uniprotkb": "Hedgehog protein", "protein_names_refseq": "desert hedgehog protein", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5358346); (R-BTA-5362798); (R-BTA-5632681); (R-BTA-5635838)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The C-terminal part of the desert hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity. Both activities result in the cleavage of the full-length protein into two parts (N-product and C-product) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product (DHH-N). Both activities occur in the endoplasmic reticulum. Once cleaved, the C-product is degraded in the endoplasmic reticulum. Functions in cell-cell mediated juxtacrine signaling. Promotes endothelium integrity. Binds to PTCH1 receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes in endothelial cells. In Schwann cells, controls the development of the peripheral nerve sheath and the transition of mesenchymal cells to form the epithelium-like structure of the perineurial tube., [UniProtKB, UniProtKB, UniProtKB]; The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product., [UniProtKB, UniProtKB, UniProtKB]; The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0016740 transferase activity;GO:0008233 peptidase activity;GO:0005113 patched binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0048731 system development;GO:0001708 cell fate specification;GO:0045880 positive regulation of smoothened signaling pathway;GO:0007267 cell-cell signaling;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MFP2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MGU0-1", "uniprot_id": "F1MGU0_BOVIN", "mass": 82956.0, "length": 748, "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "organism": "Bovine", "refseq_name": "death domain-associated protein 6 isoform X1", "refseq_ac": "XP_015315200", "gene_names_uniprotkb": "DAXX", "gene_names_refseq": "DAXX", "protein_names_uniprotkb": "Death domain-associated protein 6; Daxx", "protein_names_refseq": "death domain-associated protein 6 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3899300); (R-BTA-6804757); (R-BTA-9670095)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0019901 protein kinase binding;GO:0003714 transcription corepressor activity;GO:0030295 protein kinase activator activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000775 chromosome, centromeric region;GO:0016605 PML body", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010629 negative regulation of gene expression;GO:0007254 JNK cascade;GO:0034605 cellular response to heat;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MGU0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MH24-1", "uniprot_id": "AAK1_BOVIN", "mass": 103089.0, "length": 957, "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AAK1", "gene_names_refseq": "", "protein_names_uniprotkb": "AP2-associated protein kinase 1; 2.7.11.1; Adaptor-associated kinase 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "11877461", "class_list": "", "function": "Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Preferentially, may phosphorylate substrates on threonine residues. Regulates phosphorylation of other AP-2 subunits as well as AP-2 localization and AP-2-mediated internalization of ligand complexes. Phosphorylates NUMB and regulates its cellular localization, promoting NUMB localization to endosomes. Binds to and stabilizes the activated form of NOTCH1, increases its localization in endosomes and regulates its transcriptional activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 19, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0005112 Notch binding;GO:0035612 AP-2 adaptor complex binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0031252 cell leading edge;GO:0043195 terminal bouton;GO:0030136 clathrin-coated vesicle", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0006897 endocytosis;GO:0032880 regulation of protein localization;GO:0045747 positive regulation of Notch signaling pathway;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MH24-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MHN9-1", "uniprot_id": "F1MHN9_BOVIN", "mass": 58450.0, "length": 516, "protein_name": "Cytochrome P450 1A", "gene_name": "CYP1A2", "organism": "Bovine", "refseq_name": "cytochrome P450 1A2", "refseq_ac": "XP_010815441", "gene_names_uniprotkb": "CYP1A2", "gene_names_refseq": "CYP1A2", "protein_names_uniprotkb": "Cytochrome P450 1A; 1.14.14.1", "protein_names_refseq": "cytochrome P450 1A2", "tax_id": 9913, "disease": "", "pathway": " (bta:503552); (R-BTA-156581); (R-BTA-211957); (R-BTA-2142670); (R-BTA-2142816); (R-BTA-5423646); (R-BTA-9018681); (R-BTA-9027307)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.2.1.152;5.3.99.5;1.14.14.1;1.14.14.19;1.14.14.32;1.14.13.n7;1.14.14.-;1.14.14.14;1.14.14.80;5.3.99.4", "go_molecular_function": "GO:0101020 estrogen 16-alpha-hydroxylase activity;GO:0005506 iron ion binding;GO:0019899 enzyme binding;GO:0020037 heme binding;GO:0032451 demethylase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0008210 estrogen metabolic process;GO:0016098 monoterpenoid metabolic process;GO:0042572 retinol metabolic process;GO:0042178 xenobiotic catabolic process;GO:0009404 toxin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MHN9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MII8-1", "uniprot_id": "F1MII8_BOVIN", "mass": 59523.0, "length": 543, "protein_name": "Solute carrier family 22 member 8", "gene_name": "SLC22A8", "organism": "Bovine", "refseq_name": "organic anion transporter 3", "refseq_ac": "NP_001193175", "gene_names_uniprotkb": "SLC22A8", "gene_names_refseq": "OAT3; SLC22A8", "protein_names_uniprotkb": "Solute carrier family 22 member 8", "protein_names_refseq": "organic anion transporter 3", "tax_id": 9913, "disease": "", "pathway": " (bta:404128); (R-BTA-561048)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042910 xenobiotic transmembrane transporter activity;GO:0005452 solute:inorganic anion antiporter activity;GO:0015132 prostaglandin transmembrane transporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0015711 organic anion transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MII8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MJR8-1", "uniprot_id": "TEX14_BOVIN", "mass": 165254.0, "length": 1493, "protein_name": "Inactive serine/threonine-protein kinase TEX14", "gene_name": "TEX14", "organism": "Bovine", "refseq_name": "inactive serine/threonine-protein kinase TEX14", "refseq_ac": "NP_001179497", "gene_names_uniprotkb": "TEX14", "gene_names_refseq": "TEX14", "protein_names_uniprotkb": "Inactive serine/threonine-protein kinase TEX14; Testis-expressed sequence 14 protein; Testis-expressed sequence 14", "protein_names_refseq": "inactive serine/threonine-protein kinase TEX14; testis-expressed sequence 14 protein", "tax_id": 9913, "disease": "", "pathway": " (bta:522810)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0045171 intercellular bridge;GO:0000776 kinetochore;GO:0030496 midbody", "go_biological_process": "GO:0043063 intercellular bridge organization;GO:0008608 attachment of spindle microtubules to kinetochore;GO:0051301 cell division;GO:0051306 mitotic sister chromatid separation;GO:0007094 mitotic spindle assembly checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MJR8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MK03-1", "uniprot_id": "F1MK03_BOVIN", "mass": 61372.0, "length": 558, "protein_name": "Hepatocyte nuclear factor 1-beta", "gene_name": "HNF1B", "organism": "Bovine", "refseq_name": "hepatocyte nuclear factor 1-beta isoform X1", "refseq_ac": "XP_005220037", "gene_names_uniprotkb": "HNF1B", "gene_names_refseq": "HNF-1b; HNF1B", "protein_names_uniprotkb": "Hepatocyte nuclear factor 1-beta; Transcription factor 2", "protein_names_refseq": "hepatocyte nuclear factor 1-beta isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor that binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Binds to the FPC element in the cAMP regulatory unit of the PLAU gene. Transcriptional activity is increased by coactivator PCBD1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1990841 promoter-specific chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0001889 liver development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0031016 pancreas development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MK03-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLB2-1", "uniprot_id": "F1MLB2_BOVIN", "mass": 291630.0, "length": 2591, "protein_name": "Chromodomain-helicase-DNA-binding protein 8", "gene_name": "CHD8", "organism": "Bovine", "refseq_name": "chromodomain-helicase-DNA-binding protein 8 isoform X1", "refseq_ac": "XP_024853122", "gene_names_uniprotkb": "CHD8", "gene_names_refseq": "CHD8", "protein_names_uniprotkb": "Chromodomain-helicase-DNA-binding protein 8; 3.6.4.-; ATP-dependent helicase CHD8; CHD-8", "protein_names_refseq": "chromodomain-helicase-DNA-binding protein 8 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3769402); (R-BTA-9943962)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "ATP-dependent chromatin-remodeling factor, it slides nucleosomes along DNA; nucleosome sliding requires ATP. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. Involved in both enhancer blocking and epigenetic remodeling at chromatin boundary via its interaction with CTCF. Acts as a suppressor of STAT3 activity by suppressing the LIF-induced STAT3 transcriptional activity. Also acts as a transcription activator via its interaction with ZNF143 by participating in efficient U6 RNA polymerase III transcription., [UniProtKB, HAMAP]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0071339 MLL1 complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006397 mRNA processing;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLB2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MLT3-1", "uniprot_id": "F1MLT3_BOVIN", "mass": 23696.0, "length": 217, "protein_name": "Heart- and neural crest derivatives-expressed protein 2", "gene_name": "HAND2", "organism": "Bovine", "refseq_name": "heart- and neural crest derivatives-expressed protein 2", "refseq_ac": "XP_003586406", "gene_names_uniprotkb": "HAND2", "gene_names_refseq": "HAND2", "protein_names_uniprotkb": "Heart- and neural crest derivatives-expressed protein 2; Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2", "protein_names_refseq": "heart- and neural crest derivatives-expressed protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:781874)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003680 minor groove of adenine-thymine-rich DNA binding;GO:0042803 protein homodimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005667 transcription regulator complex;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007507 heart development;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MLT3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MM97-1", "uniprot_id": "F1MM97_BOVIN", "mass": 49610.0, "length": 464, "protein_name": "Hedgehog protein", "gene_name": "SHH", "organism": "Bovine", "refseq_name": "sonic hedgehog protein", "refseq_ac": "XP_024847069", "gene_names_uniprotkb": "SHH", "gene_names_refseq": "SHH", "protein_names_uniprotkb": "Hedgehog protein", "protein_names_refseq": "sonic hedgehog protein", "tax_id": 9913, "disease": "", "pathway": " (bta:286821); (R-BTA-5358346); (R-BTA-5362798); (R-BTA-5632681); (R-BTA-5635838)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product., [UniProtKB, UniProtKB]; The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0008233 peptidase activity;GO:0005539 glycosaminoglycan binding;GO:0005113 patched binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0031012 extracellular matrix", "go_biological_process": "GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment;GO:0001708 cell fate specification;GO:0045880 positive regulation of smoothened signaling pathway;GO:0003140 determination of left/right asymmetry in lateral mesoderm;GO:0009949 polarity specification of anterior/posterior axis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MM97-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MN68-1", "uniprot_id": "F1MN68_BOVIN", "mass": 42545.0, "length": 385, "protein_name": "Nuclear receptor subfamily 2 group E member 1", "gene_name": "NR2E1", "organism": "Bovine", "refseq_name": "nuclear receptor subfamily 2 group E member 1", "refseq_ac": "NP_001179582", "gene_names_uniprotkb": "NR2E1", "gene_names_refseq": "NR2E1", "protein_names_uniprotkb": "Nuclear receptor subfamily 2 group E member 1; Nuclear receptor TLX; Protein tailless homolog", "protein_names_refseq": "nuclear receptor subfamily 2 group E member 1", "tax_id": 9913, "disease": "", "pathway": " (bta:528156); (R-BTA-383280)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042826 histone deacetylase binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:2000648 positive regulation of stem cell proliferation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MN68-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MNF8-1", "uniprot_id": "F1MNF8_BOVIN", "mass": 50136.0, "length": 451, "protein_name": "Tubulin alpha chain", "gene_name": "TUBA1A", "organism": "Bovine", "refseq_name": "tubulin alpha-1B chain", "refseq_ac": "NP_001159977", "gene_names_uniprotkb": "TUBA1A", "gene_names_refseq": "TUBA1A", "protein_names_uniprotkb": "Tubulin alpha chain", "protein_names_refseq": "alpha-tubulin ubiquitous; tubulin K-alpha-1; tubulin alpha-1B chain; tubulin alpha-ubiquitous chain", "tax_id": 9913, "disease": "", "pathway": " (bta:404053); (R-BTA-2132295); (R-BTA-2467813); (R-BTA-2500257); (R-BTA-3371497); (R-BTA-5620924); (R-BTA-6807878); (R-BTA-6811436); (R-BTA-9013407); (R-BTA-9646399); (R-BTA-9648025)", "pathway_count": 11, "publication_count": 6, "publication_id_list": "22022409;23358242;24245503;24940781;25908846;28250419", "class_list": "", "function": "Data suggest presence of unstructured C-terminal tubulin tail in Vdac1 pore (voltage-dependent anion channel 1) decreases pore's conductance and switches pore's selectivity from anionic to cationic rendering ATP transport virtually impossible., [RefSeq, PubMed]; Lys40 of alpha-tubulin acetylation directly weakens inter-protofilament interactions., [RefSeq, PubMed]; Lysine 40 acetylation of alpha-tubulin does not result in significant changes in kinesin-1's landing rate or motility parameters., [RefSeq, PubMed]; TTL has specifically evolved to recognize and modify tubulin., [RefSeq, PubMed]; The role of the human TBCE and TBCB chaperones in alpha-tubulin-beta-tubulin dissociation, was investigated., [RefSeq, PubMed]; Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin., [UniProtKB, UniProtKB]; VDAC phosphorylation is an important determinant of its interaction with dimeric tubulin., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding;GO:0008017 microtubule binding;GO:0016787 hydrolase activity;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005874 microtubule;GO:0005886 plasma membrane;GO:0031594 neuromuscular junction", "go_biological_process": "GO:0046785 microtubule polymerization;GO:0021696 cerebellar cortex morphogenesis;GO:0001964 startle response;GO:0000278 mitotic cell cycle;GO:0006886 intracellular protein transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1MNF8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MNG1-1", "uniprot_id": "F1MNG1_BOVIN", "mass": 60239.0, "length": 539, "protein_name": "17-alpha-hydroxyprogesterone aldolase", "gene_name": "CYP1B1", "organism": "Bovine", "refseq_name": "cytochrome P450 1B1", "refseq_ac": "NP_001179223", "gene_names_uniprotkb": "CYP1B1", "gene_names_refseq": "CYP1B1", "protein_names_uniprotkb": "17-alpha-hydroxyprogesterone aldolase", "protein_names_refseq": "cytochrome P450 1B1; cytochrome P450, family 1, subfamily B, polypeptide 1", "tax_id": 9913, "disease": "", "pathway": " (bta:511470); (R-BTA-211976); (R-BTA-2142670); (R-BTA-2142816)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.14.19;1.14.14.32;1.14.14.1", "go_molecular_function": "GO:0101020 estrogen 16-alpha-hydroxylase activity;GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016829 lyase activity;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0002930 trabecular meshwork development;GO:0008210 estrogen metabolic process;GO:0007155 cell adhesion;GO:0008285 negative regulation of cell population proliferation;GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MNG1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MNN4-2", "uniprot_id": "FBXW7_BOVIN", "mass": 79663.0, "length": 706, "protein_name": "F-box/WD repeat-containing protein 7", "gene_name": "FBXW7", "organism": "Bovine", "refseq_name": "F-box/WD repeat-containing protein 7", "refseq_ac": "NP_001069717", "gene_names_uniprotkb": "FBXW7; FBW7", "gene_names_refseq": "FBXW7", "protein_names_uniprotkb": "F-box/WD repeat-containing protein 7; F-box and WD-40 domain-containing protein 7", "protein_names_refseq": "F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase; F-box and WD-40 domain-containing protein 7; F-box/WD repeat-containing protein 7", "tax_id": 9913, "disease": "", "pathway": " (bta:540932); (R-BTA-8951664); (R-BTA-983168)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "19393038;25624101", "class_list": "", "function": "Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter brings them to the SCF complex for ubiquitination (By similarity). Identified substrates include cyclin-E (CCNE1 or CCNE2), DISC1, JUN, MYC, NOTCH1 released notch intracellular domain (NICD), NOTCH2, MCL1, MLST8, RICTOR, and probably PSEN1. Acts as a negative regulator of JNK signaling by binding to phosphorylated JUN and promoting its ubiquitination and subsequent degradation (By similarity). SCF(FBXW7) complex mediates the ubiquitination and subsequent degradation of NFE2L1 (By similarity). Involved in bone homeostasis and negative regulation of osteoclast differentiation (By similarity). Also able to promote 'Lys-63'-linked ubiquitination in response to DNA damage (By similarity). The SCF(FBXW7) complex facilitates double-strand break repair following phosphorylation by ATM: phosphorylation promotes localization to sites of double-strand breaks and 'Lys-63'-linked ubiquitination of phosphorylated XRCC4, enhancing DNA non-homologous end joining (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A3Q1N420;Q0VCX6", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0043130 ubiquitin binding;GO:1990756 ubiquitin-like ligase-substrate adaptor activity;GO:0050816 phosphothreonine residue binding", "go_cellular_component": "GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0019005 SCF ubiquitin ligase complex", "go_biological_process": "GO:0010992 ubiquitin recycling;GO:0006281 DNA repair;GO:0010629 negative regulation of gene expression;GO:1903955 positive regulation of protein targeting to mitochondrion;GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1MNN4-2", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MQ37-1", "uniprot_id": "F1MQ37_BOVIN", "mass": 227204.0, "length": 1965, "protein_name": "Myosin-9", "gene_name": "MYH9", "organism": "Bovine", "refseq_name": "myosin-9", "refseq_ac": "NP_001179691", "gene_names_uniprotkb": "MYH9", "gene_names_refseq": "MYH9", "protein_names_uniprotkb": "Myosin-9; Cellular myosin heavy chain, type A; Myosin heavy chain 9; Myosin heavy chain, non-muscle IIa; Non-muscle myosin heavy chain A; Non-muscle myosin heavy chain IIa", "protein_names_refseq": "myosin, heavy chain 9, non-muscle; myosin-9", "tax_id": 9913, "disease": "", "pathway": " (bta:404108); (R-BTA-5627123)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Required for cortical actin clearance prior to oocyte exocytosis. Promotes cell motility in conjunction with S100A4. During cell spreading, plays an important role in cytoskeleton reorganization, focal contact formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0019904 protein domain specific binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005819 spindle;GO:0005829 cytosol;GO:0005903 brush border", "go_biological_process": "GO:0001778 plasma membrane repair;GO:1903923 positive regulation of protein processing in phagocytic vesicle;GO:0001525 angiogenesis;GO:0006509 membrane protein ectodomain proteolysis;GO:0006911 phagocytosis, engulfment", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MQ37-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MSK8-1", "uniprot_id": "F1MSK8_BOVIN", "mass": 45571.0, "length": 405, "protein_name": "Hyaluronidase", "gene_name": "HYAL1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HYAL1", "gene_names_refseq": "", "protein_names_uniprotkb": "Hyaluronidase; 3.2.1.35", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2024101); (R-BTA-2160916)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.2.1.35", "go_molecular_function": "GO:0004415 hyalurononglucosaminidase activity;GO:0052757 chondroitin hydrolase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome;GO:0031410 cytoplasmic vesicle;GO:0036117 hyaluranon cable", "go_biological_process": "GO:0071493 cellular response to UV-B;GO:0006954 inflammatory response;GO:0030307 positive regulation of cell growth;GO:0045785 positive regulation of cell adhesion;GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MSK8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MUZ3-1", "uniprot_id": "F1MUZ3_BOVIN", "mass": 48111.0, "length": 425, "protein_name": "Mothers against decapentaplegic homolog", "gene_name": "SMAD3", "organism": "Bovine", "refseq_name": "SMAD family member 3", "refseq_ac": "NP_001192734", "gene_names_uniprotkb": "SMAD3", "gene_names_refseq": "SMAD3", "protein_names_uniprotkb": "Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member", "protein_names_refseq": "SMAD family member 3", "tax_id": 9913, "disease": "", "pathway": " (bta:515125); (R-BTA-1181150); (R-BTA-1502540); (R-BTA-2173788); (R-BTA-2173789); (R-BTA-2173795); (R-BTA-2173796); (R-BTA-5689880); (R-BTA-8941855); (R-BTA-9008059); (R-BTA-9617828)", "pathway_count": 11, "publication_count": 5, "publication_id_list": "23804438;24795273;26289443;29672161;31071302", "class_list": "", "function": "A detailed computational model for TGF-beta signalling that incorporates elements of previous models together with crosstalking between Smad1/5/8 and Smad2/3 channels through a negative feedback loop dependent on Smad7. Publication Status: Online-Only, [RefSeq, PubMed]; Data show that the transcription factor Smad3 (Smad3) gene was expressed ubiquitously in 11 bovine tissues and displayed different expression patterns between muscle and adipose tissue., [RefSeq, PubMed]; Mechanical compression not only with physiological but also with excessive stress can activate Smad2/3P signaling, which is known to be protective for articular cartilage and to block chondrocyte terminal differentiation., [RefSeq, PubMed]; Smad3 protein inhibits Smad2 expression via binding to C-EBPalpha and C-EBPbeta proteins., [RefSeq, PubMed]; The present work provides evidence supporting a functional role of SMAD2/3 in bovine early embryogenesis, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070410 co-SMAD binding;GO:0031962 nuclear mineralocorticoid receptor binding;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0071144 heteromeric SMAD protein complex;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006955 immune response;GO:0010628 positive regulation of gene expression;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "F1MUZ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MVT0-1", "uniprot_id": "F1MVT0_BOVIN", "mass": 53638.0, "length": 502, "protein_name": "Forkhead box protein L2", "gene_name": "FOXC2", "organism": "Bovine", "refseq_name": "forkhead box protein C2", "refseq_ac": "NP_001180001", "gene_names_uniprotkb": "FOXC2", "gene_names_refseq": "FOXC2", "protein_names_uniprotkb": "Forkhead box protein L2", "protein_names_refseq": "forkhead box C2 (MFH-1, mesenchyme forkhead 1); forkhead box protein C2", "tax_id": 9913, "disease": "", "pathway": " (bta:507300)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0031490 chromatin DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0016604 nuclear body", "go_biological_process": "GO:0035470 positive regulation of vascular wound healing;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007507 heart development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MVT0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MX38-1", "uniprot_id": "F1MX38_BOVIN", "mass": 84373.0, "length": 737, "protein_name": "Signal transducer and activator of transcription", "gene_name": "STAT3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "STAT3", "gene_names_refseq": "", "protein_names_uniprotkb": "Signal transducer and activator of transcription", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1059683); (R-BTA-1266695); (R-BTA-1433557); (R-BTA-186763); (R-BTA-201556); (R-BTA-6783783); (R-BTA-6785807); (R-BTA-8849474); (R-BTA-8854691); (R-BTA-8875791); (R-BTA-8983432); (R-BTA-8984722); (R-BTA-8985947); (R-BTA-9008059); (R-BTA-9020933); (R-BTA-9020956); (R-BTA-9020958); (R-BTA-9701898); (R-BTA-9833482); (R-BTA-9958825)", "pathway_count": 20, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0019901 protein kinase binding;GO:0042803 protein homodimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0070120 ciliary neurotrophic factor-mediated signaling pathway;GO:0038110 interleukin-2-mediated signaling pathway;GO:0048708 astrocyte differentiation;GO:1905564 positive regulation of vascular endothelial cell proliferation;GO:2000635 negative regulation of primary miRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1MX38-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1MYR9-1", "uniprot_id": "KCNJ5_BOVIN", "mass": 47657.0, "length": 419, "protein_name": "G protein-activated inward rectifier potassium channel 4", "gene_name": "KCNJ5", "organism": "Bovine", "refseq_name": "G protein-activated inward rectifier potassium channel 4", "refseq_ac": "XP_002699270", "gene_names_uniprotkb": "KCNJ5; GIRK4", "gene_names_refseq": "KCNJ5", "protein_names_uniprotkb": "G protein-activated inward rectifier potassium channel 4; Cardiac inward rectifier; GIRK-4; Heart KATP channel; Inward rectifier K(+) channel Kir3.4; KATP-1; Potassium channel, inwardly rectifying subfamily J member 5", "protein_names_refseq": "G protein-activated inward rectifier potassium channel 4", "tax_id": 9913, "disease": "", "pathway": " (bta:539844); (R-BTA-1296041); (R-BTA-997272)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat. Can be blocked by external barium. This potassium channel is controlled by G proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.-.-", "go_molecular_function": "GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization;GO:0015467 G-protein activated inward rectifier potassium channel activity;GO:0005242 inward rectifier potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:1990566 I(KACh) inward rectifier potassium channel complex", "go_biological_process": "GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential;GO:0086091 regulation of heart rate by cardiac conduction;GO:1990573 potassium ion import across plasma membrane;GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1MYR9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N0D3-1", "uniprot_id": "F1N0D3_BOVIN", "mass": 97747.0, "length": 887, "protein_name": "Tyrosine-protein kinase receptor UFO", "gene_name": "AXL", "organism": "Bovine", "refseq_name": "tyrosine-protein kinase receptor UFO isoform X1", "refseq_ac": "XP_024834863", "gene_names_uniprotkb": "AXL", "gene_names_refseq": "AXL", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor UFO; 2.7.10.1", "protein_names_refseq": "tyrosine-protein kinase receptor UFO isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.1;2.7.10.4", "go_molecular_function": "GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0045087 innate immune response;GO:0006909 phagocytosis;GO:0009967 positive regulation of signal transduction;GO:0001818 negative regulation of cytokine production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N0D3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N0W0-1", "uniprot_id": "F1N0W0_BOVIN", "mass": 48848.0, "length": 428, "protein_name": "Histone deacetylase 3", "gene_name": "HDAC3", "organism": "Bovine", "refseq_name": "histone deacetylase 3", "refseq_ac": "NP_001193172", "gene_names_uniprotkb": "HDAC3", "gene_names_refseq": "HDAC3", "protein_names_uniprotkb": "Histone deacetylase 3; 3.5.1.98; HD3", "protein_names_refseq": "histone deacetylase 3", "tax_id": 9913, "disease": "", "pathway": " (bta:404125); (R-BTA-3214815); (R-BTA-350054); (R-BTA-381340); (R-BTA-400206); (R-BTA-9029569); (R-BTA-9701898); (R-BTA-9707564); (R-BTA-9841922)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "30317681", "class_list": "", "function": "Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes., [UniProtKB, UniProtKB]; The use of mesenchymal stem cells (MSC) less methylated and more hydroxymethylated in combination with embryo incubation with TSA can induce lower expression of HDAC3 and higher expression of KAT2A in the embryos and consequently improve bovine embryo production., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.1.98;2.1.1.319;2.3.1.48;2.3.1.286;2.7.11.1;3.5.1.-", "go_molecular_function": "GO:0046872 metal ion binding;GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding;GO:0051059 NF-kappaB binding;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0017053 transcription repressor complex;GO:0000785 chromatin;GO:0000118 histone deacetylase complex;GO:0072686 mitotic spindle", "go_biological_process": "GO:0042307 positive regulation of protein import into nucleus;GO:0060816 random inactivation of X chromosome;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0001701 in utero embryonic development;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1N0W0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N1F9-1", "uniprot_id": "F1N1F9_BOVIN", "mass": 43061.0, "length": 410, "protein_name": "SRY-box transcription factor 17", "gene_name": "SOX17", "organism": "Bovine", "refseq_name": "transcription factor SOX-17", "refseq_ac": "NP_001193180", "gene_names_uniprotkb": "SOX17", "gene_names_refseq": "SOX17", "protein_names_uniprotkb": "SRY-box transcription factor 17", "protein_names_refseq": "SRY (sex determining region Y)-box 17; SRY-box 17; transcription factor SOX-17", "tax_id": 9913, "disease": "", "pathway": " (bta:534010); (R-BTA-3769402)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "31272387", "class_list": "", "function": "This study shows that SOX17 can be used as a reliable early marker of hypoblast in the bovine, and based on its expression profile, the hypoblast segregates in day 7 blastocysts. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0008013 beta-catenin binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0001714 endodermal cell fate specification;GO:0061031 endodermal digestive tract morphogenesis;GO:0060913 cardiac cell fate determination;GO:0001525 angiogenesis;GO:0001570 vasculogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1N1F9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N1M2-1", "uniprot_id": "F1N1M2_BOVIN", "mass": 59512.0, "length": 593, "protein_name": "GATA binding protein 6", "gene_name": "GATA6", "organism": "Bovine", "refseq_name": "transcription factor GATA-6", "refseq_ac": "XP_002697773", "gene_names_uniprotkb": "GATA6", "gene_names_refseq": "GATA6", "protein_names_uniprotkb": "GATA binding protein 6", "protein_names_refseq": "transcription factor GATA-6", "tax_id": 9913, "disease": "", "pathway": " (bta:654400); (R-BTA-5683826); (R-BTA-983231)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051525 NFAT protein binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0002759 regulation of antimicrobial humoral response;GO:0098773 skin epidermis development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0030855 epithelial cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N1M2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N261-1", "uniprot_id": "F1N261_BOVIN", "mass": 58735.0, "length": 512, "protein_name": "Tyrosine-protein kinase", "gene_name": "LYN", "organism": "Bovine", "refseq_name": "tyrosine-protein kinase Lyn", "refseq_ac": "NP_001171211", "gene_names_uniprotkb": "LYN", "gene_names_refseq": "LYN", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "tyrosine-protein kinase Lyn; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:534996); (R-BTA-114604); (R-BTA-1433557); (R-BTA-1433559); (R-BTA-210990); (R-BTA-2454202); (R-BTA-2730905); (R-BTA-2871796); (R-BTA-2871809); (R-BTA-2871837); (R-BTA-389356); (R-BTA-389513); (R-BTA-3928663); (R-BTA-3928665); (R-BTA-5621480); (R-BTA-5690714); (R-BTA-69231); (R-BTA-75892); (R-BTA-9006335); (R-BTA-9027276); (R-BTA-9027284); (R-BTA-912631); (R-BTA-9674555); (R-BTA-9705462); (R-BTA-982772)", "pathway_count": 25, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;3.6.5.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.1;2.3.2.27;3.1.4.11;2.7.11.13;2.7.11.24;2.7.11.22;2.7.1.153;2.7.1.137;3.1.3.48;3.1.3.16;2.7.10.4;2.3.2.24;2.3.2.23", "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005102 signaling receptor binding;GO:0005524 ATP binding;GO:0017124 SH3 domain binding;GO:0030546 signaling receptor activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0045121 membrane raft", "go_biological_process": "GO:0033628 regulation of cell adhesion mediated by integrin;GO:0002431 Fc receptor mediated stimulatory signaling pathway;GO:0002513 tolerance induction to self antigen;GO:0030222 eosinophil differentiation;GO:0038043 interleukin-5-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N261-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N2L9-1", "uniprot_id": "F1N2L9_BOVIN", "mass": 51210.0, "length": 466, "protein_name": "4-trimethylaminobutyraldehyde dehydrogenase", "gene_name": "ALDH9A1", "organism": "Bovine", "refseq_name": "4-trimethylaminobutyraldehyde dehydrogenase isoform X1", "refseq_ac": "XP_005203489", "gene_names_uniprotkb": "ALDH9A1", "gene_names_refseq": "ALDH9A1; TMABA-DH", "protein_names_uniprotkb": "4-trimethylaminobutyraldehyde dehydrogenase; 1.2.1.19; 1.2.1.3; 1.2.1.46; 1.2.1.47; Aldehyde dehydrogenase family 9 member A1; Formaldehyde dehydrogenase; Gamma-aminobutyraldehyde dehydrogenase", "protein_names_refseq": "4-trimethylaminobutyraldehyde dehydrogenase isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-71262)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. Catalyzes the oxidation of aldehydes arising from biogenic amines and polyamines., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.2.1.3;1.2.1.31;1.2.1.8;1.2.1.36;1.2.1.19;1.2.1.28;1.2.1.5;1.2.1.47;1.2.1.46;1.7.1.-;1.2.1.7;1.2.1.48", "go_molecular_function": "GO:0018467 formaldehyde dehydrogenase (NAD+) activity;GO:0019145 aminobutyraldehyde dehydrogenase (NAD+) activity;GO:0047105 4-trimethylammoniobutyraldehyde dehydrogenase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0045329 carnitine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N2L9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N3R6-1", "uniprot_id": "F1N3R6_BOVIN", "mass": 109971.0, "length": 987, "protein_name": "Ephrin type-B receptor 2", "gene_name": "EPHB2", "organism": "Bovine", "refseq_name": "ephrin type-B receptor 2 isoform X1", "refseq_ac": "XP_024831663", "gene_names_uniprotkb": "EPHB2", "gene_names_refseq": "EPHB2", "protein_names_uniprotkb": "Ephrin type-B receptor 2; 2.7.10.1; Tyrosine-protein kinase receptor EPH-3", "protein_names_refseq": "ephrin type-B receptor 2 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2682334); (R-BTA-3928662); (R-BTA-3928664); (R-BTA-3928665)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;2.7.11.1;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;3.4.24.24;3.4.24.35;3.6.4.-;3.6.5.2;2.7.10.4;3.4.23.-", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0001540 amyloid-beta binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:0001525 angiogenesis;GO:0007162 negative regulation of cell adhesion;GO:0007611 learning or memory;GO:0030335 positive regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N3R6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N4I3-1", "uniprot_id": "F1N4I3_BOVIN", "mass": 50628.0, "length": 443, "protein_name": "D(2) dopamine receptor", "gene_name": "DRD2", "organism": "Bovine", "refseq_name": "D(2) dopamine receptor", "refseq_ac": "NP_776468", "gene_names_uniprotkb": "DRD2", "gene_names_refseq": "DRD2", "protein_names_uniprotkb": "D(2) dopamine receptor; Dopamine D2 receptor", "protein_names_refseq": "D(2) dopamine receptor; dopamine D2 receptor", "tax_id": 9913, "disease": "", "pathway": " (bta:281126); (R-BTA-390651)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "24299180;31208851", "class_list": "", "function": "Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5., [UniProtKB, UniProtKB, UniProtKB]; Studied a novel Dopamine Receptor 2 (DRD2) G/A SNP for resistance to fescue toxicosis., [RefSeq, PubMed]; The DRD2 genotype was not associated with semen quality, serum Prolactin, or growth traits., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go;GO:0004930 G protein-coupled receptor activity;GO:0042802 identical protein binding;GO:0032795 heterotrimeric G-protein binding;GO:0001965 G-protein alpha-subunit binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0030424 axon", "go_biological_process": "GO:0034776 response to histamine;GO:0060158 phospholipase C-activating dopamine receptor signaling pathway;GO:1990384 hyaloid vascular plexus regression;GO:0014059 regulation of dopamine secretion;GO:0050482 arachidonate secretion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1N4I3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N4J9-1", "uniprot_id": "F1N4J9_BOVIN", "mass": 46834.0, "length": 427, "protein_name": "Proteinase-activated receptor 1", "gene_name": "F2R", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "F2R", "gene_names_refseq": "", "protein_names_uniprotkb": "Proteinase-activated receptor 1; Thrombin receptor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-375276); (R-BTA-416476); (R-BTA-456926); (R-BTA-9769739)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "High affinity receptor that binds the activated thrombin, leading to calcium release from intracellular stores. The thrombin-activated receptor signaling pathway is mediated through PTX-insensitive G proteins, activation of phospholipase C resulting in the production of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) which binds to InsP3 receptors causing calcium release from the stores. In astrocytes, the calcium released into the cytosol allows the Ca(2+)-dependent release of L-glutamate into the synaptic cleft through BEST1, that targets the neuronal postsynaptic GRIN2A/NMDAR receptor resulting in the synaptic plasticity regulation. May play a role in platelets activation and in vascular development. Mediates up-regulation of pro-inflammatory cytokines, such as MCP-1/CCL2 and IL6, triggered by coagulation factor Xa (F10) in cardiac fibroblasts and umbilical vein endothelial cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015057 thrombin-activated receptor activity;GO:0031681 G-protein beta-subunit binding;GO:0005102 signaling receptor binding;GO:0001965 G-protein alpha-subunit binding", "go_cellular_component": "GO:0031094 platelet dense tubular network;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0045202 synapse", "go_biological_process": "GO:1900134 negative regulation of renin secretion into blood stream;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0008285 negative regulation of cell population proliferation;GO:0030335 positive regulation of cell migration;GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N4J9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N4K5-1", "uniprot_id": "F1N4K5_BOVIN", "mass": 70934.0, "length": 672, "protein_name": "Forkhead box protein O1", "gene_name": "FOXO3", "organism": "Bovine", "refseq_name": "forkhead box protein O3", "refseq_ac": "NP_001193012", "gene_names_uniprotkb": "FOXO3", "gene_names_refseq": "FOXO-3; FOXO3", "protein_names_uniprotkb": "Forkhead box protein O1; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma", "protein_names_refseq": "forkhead box O3A transcription factor; forkhead box protein O3", "tax_id": 9913, "disease": "", "pathway": " (bta:535530); (R-BTA-1181150); (R-BTA-5687128); (R-BTA-9607240); (R-BTA-9614399); (R-BTA-9617629); (R-BTA-9617828); (R-BTA-9634638); (R-BTA-9841251)", "pathway_count": 9, "publication_count": 2, "publication_id_list": "18035477;20547753", "class_list": "", "function": "FOXO is a key regulator of ROS-induced apoptosis in mammalian cells., [RefSeq, PubMed]; NO/protein kinase G (PKG)-dependent downregulation of PGC-1 alpha and the ROS detoxification system in endothelial cells are mediated by the PI3K/Akt signaling pathway and subsequent inactivation of transcription factor Foxo3a., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005741 mitochondrial outer membrane;GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006417 regulation of translation;GO:0042594 response to starvation;GO:0030336 negative regulation of cell migration;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1N4K5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N5T3-1", "uniprot_id": "F1N5T3_BOVIN", "mass": 239074.0, "length": 2138, "protein_name": "Voltage-dependent L-type calcium channel subunit alpha", "gene_name": "CACNA1C", "organism": "Bovine", "refseq_name": "voltage-dependent L-type calcium channel subunit alpha-1C isoform X14", "refseq_ac": "XP_024848531", "gene_names_uniprotkb": "CACNA1C", "gene_names_refseq": "CACNA1C", "protein_names_uniprotkb": "Voltage-dependent L-type calcium channel subunit alpha", "protein_names_refseq": "voltage-dependent L-type calcium channel subunit alpha-1C isoform X14", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-422356); (R-BTA-5576892); (R-BTA-5576893)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm. Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressure regulation via its role in the contraction of arterial smooth muscle cells. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group., [UniProtKB, UniProtKB, UniProtKB]; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0046872 metal ion binding;GO:0008331 high voltage-gated calcium channel activity;GO:0005245 voltage-gated calcium channel activity", "go_cellular_component": "GO:0030425 dendrite;GO:0043204 perikaryon;GO:0030315 T-tubule;GO:0005891 voltage-gated calcium channel complex;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0098703 calcium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N5T3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N6H1-1", "uniprot_id": "F1N6H1_BOVIN", "mass": 519753.0, "length": 4649, "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "organism": "Bovine", "refseq_name": "low-density lipoprotein receptor-related protein 2", "refseq_ac": "XP_059734109", "gene_names_uniprotkb": "LRP2", "gene_names_refseq": "LRP2", "protein_names_uniprotkb": "Low-density lipoprotein receptor-related protein 2; Glycoprotein 330; Megalin", "protein_names_refseq": "low-density lipoprotein receptor-related protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:100337021); (R-BTA-196791); (R-BTA-8856825); (R-BTA-8856828); (R-BTA-975634); (R-BTA-9758890)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0051087 protein-folding chaperone binding;GO:0005509 calcium ion binding;GO:0042562 hormone binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0030424 axon", "go_biological_process": "GO:0015031 protein transport;GO:0008584 male gonad development;GO:0001843 neural tube closure;GO:0030514 negative regulation of BMP signaling pathway;GO:0006898 receptor-mediated endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N6H1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N6M9-1", "uniprot_id": "F1N6M9_BOVIN", "mass": 68964.0, "length": 647, "protein_name": "Dishevelled segment polarity protein 1", "gene_name": "DVL1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DVL1", "gene_names_refseq": "", "protein_names_uniprotkb": "Dishevelled segment polarity protein 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:523325); (R-BTA-201688); (R-BTA-4086400); (R-BTA-4641258); (R-BTA-4641262); (R-BTA-5663220)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005109 frizzled binding;GO:0019901 protein kinase binding;GO:0042802 identical protein binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098992 neuronal dense core vesicle;GO:0005829 cytosol;GO:0014069 postsynaptic density;GO:0030426 growth cone", "go_biological_process": "GO:0099054 presynapse assembly;GO:0035556 intracellular signal transduction;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032880 regulation of protein localization;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N6M9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1N751-1", "uniprot_id": "F1N751_BOVIN", "mass": 42039.0, "length": 359, "protein_name": "Fucosyltransferase", "gene_name": "FUT9", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FUT9", "gene_names_refseq": "", "protein_names_uniprotkb": "Fucosyltransferase; 2.4.1.-", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-9037629)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.-;2.4.1.65;2.4.1.152", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0017083 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity", "go_cellular_component": "GO:0032588 trans-Golgi network membrane;GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0000271 polysaccharide biosynthetic process;GO:0006688 glycosphingolipid biosynthetic process;GO:0010976 positive regulation of neuron projection development;GO:0006493 protein O-linked glycosylation;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1N751-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F2Z4D5-1", "uniprot_id": "F2Z4D5_BOVIN", "mass": 28155.0, "length": 252, "protein_name": "small monomeric GTPase", "gene_name": "RAB11A", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RAB11A", "gene_names_refseq": "", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-432040); (R-BTA-5620912); (R-BTA-5620916); (R-BTA-8854214); (R-BTA-8873719)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;2.7.11.1;3.6.5.-;3.6.5.3;2.7.11.21;3.6.1.5;2.7.11.11;2.7.11.26;2.7.11.22;2.7.11.23;3.6.1.15;3.6.5.4;2.5.1.60;3.6.4.10", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0098837 postsynaptic recycling endosome;GO:0005794 Golgi apparatus;GO:0030133 transport vesicle", "go_biological_process": "GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane;GO:0006887 exocytosis;GO:0032402 melanosome transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F2Z4D5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F6Q7X7-1", "uniprot_id": "F6Q7X7_BOVIN", "mass": 32184.0, "length": 284, "protein_name": "SIX homeobox 1", "gene_name": "SIX1", "organism": "Bovine", "refseq_name": "homeobox protein SIX1", "refseq_ac": "XP_002691065", "gene_names_uniprotkb": "SIX1", "gene_names_refseq": "SIX1", "protein_names_uniprotkb": "SIX homeobox 1", "protein_names_refseq": "homeobox protein SIX1", "tax_id": 9913, "disease": "", "pathway": " (bta:511371)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0050678 regulation of epithelial cell proliferation;GO:0086100 endothelin receptor signaling pathway;GO:0061055 myotome development;GO:0061197 fungiform papilla morphogenesis;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6Q7X7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F6QA78-1", "uniprot_id": "F6QA78_BOVIN", "mass": 45327.0, "length": 412, "protein_name": "Hedgehog protein", "gene_name": "IHH", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IHH", "gene_names_refseq": "", "protein_names_uniprotkb": "Hedgehog protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5358346); (R-BTA-5362798); (R-BTA-5632681); (R-BTA-5635838)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product., [UniProtKB, UniProtKB]; The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0016740 transferase activity;GO:0008233 peptidase activity;GO:0005113 patched binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0031012 extracellular matrix;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0001708 cell fate specification;GO:0045880 positive regulation of smoothened signaling pathway;GO:0046639 negative regulation of alpha-beta T cell differentiation;GO:0007267 cell-cell signaling;GO:0033089 positive regulation of T cell differentiation in thymus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6QA78-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F6QI78-1", "uniprot_id": "F6QI78_BOVIN", "mass": 60731.0, "length": 538, "protein_name": "5-hydroxytryptamine receptor 2B", "gene_name": "HTR2B", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HTR2B", "gene_names_refseq": "", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 2B; Serotonin receptor 2B", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-390666); (R-BTA-416476)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0004993 G protein-coupled serotonin receptor activity;GO:0030594 neurotransmitter receptor activity;GO:0051378 serotonin binding;GO:0001965 G-protein alpha-subunit binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:0019722 calcium-mediated signaling;GO:0043066 negative regulation of apoptotic process;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0006874 intracellular calcium ion homeostasis;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F6QI78-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G3MYU1-1", "uniprot_id": "G3MYU1_BOVIN", "mass": 80544.0, "length": 729, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "BAP1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "BAP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5689603); (R-BTA-5693565)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.255;2.3.2.27;3.4.19.12", "go_molecular_function": "GO:0031490 chromatin DNA binding;GO:0004843 cysteine-type deubiquitinase activity;GO:0140950 histone H2A deubiquitinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005694 chromosome;GO:0035517 PR-DUB complex", "go_biological_process": "GO:0030223 neutrophil differentiation;GO:0043249 erythrocyte maturation;GO:0000278 mitotic cell cycle;GO:0001701 in utero embryonic development;GO:0001894 tissue homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3MYU1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G3MZL1-1", "uniprot_id": "G3MZL1_BOVIN", "mass": 87463.0, "length": 783, "protein_name": "Cadherin-5", "gene_name": "CDH5", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CDH5", "gene_names_refseq": "", "protein_names_uniprotkb": "Cadherin-5; Vascular endothelial cadherin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-418990); (R-BTA-5218920)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cadherins are calcium-dependent cell adhesion proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "G5E588", "ec_number_list": "", "go_molecular_function": "GO:0044325 transmembrane transporter binding;GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding;GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005912 adherens junction;GO:0005923 bicellular tight junction;GO:0009897 external side of plasma membrane;GO:0016342 catenin complex", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0016477 cell migration;GO:0030335 positive regulation of cell migration;GO:0006874 intracellular calcium ion homeostasis;GO:0045766 positive regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3MZL1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G3MZR2-1", "uniprot_id": "FUT7_BOVIN", "mass": 38746.0, "length": 342, "protein_name": "Alpha-(1,3)-fucosyltransferase 7", "gene_name": "FUT7", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FUT7", "gene_names_refseq": "", "protein_names_uniprotkb": "Alpha-(1,3)-fucosyltransferase 7; 2.4.1.-; Fuc-TVII; FucT-VII; Fucosyltransferase 7; Fucosyltransferase VII; Galactoside 3-L-fucosyltransferase; Selectin ligand synthase; bfut7", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-9037629)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "19393038;22909383", "class_list": "", "function": "Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal alpha2,3 sialylated lactosamine unit of a glycoprotein or a glycolipid-linked sialopolylactosamines chain through an alpha-1,3 glycosidic linkage and participates in the final fucosylation step in the biosynthesis of the sialyl Lewis X (sLe(x)), a carbohydrate involved in cell and matrix adhesion during leukocyte trafficking and fertilization (PubMed:22909383). In vitro, also synthesizes sialyl-dimeric-Lex structures, from VIM-2 structures and both di-fucosylated and trifucosylated structures from mono-fucosylated precursors. However does not catalyze alpha 1-3 fucosylation when an internal alpha 1-3 fucosylation is present in polylactosamine chain and the fucosylation rate of the internal GlcNAc residues is reduced once fucose has been added to the distal GlcNAc. Also catalyzes the transfer of a fucose from GDP-beta-fucose to the 6-sulfated a(2,3)sialylated substrate to produce 6-sulfo sLex mediating significant L-selectin-dependent cell adhesion. Through sialyl-Lewis(x) biosynthesis, can control SELE- and SELP-mediated cell adhesion with leukocytes and allows leukocytes tethering and rolling along the endothelial tissue thereby enabling the leukocytes to accumulate at a site of inflammation. May enhance embryo implantation through sialyl Lewis X (sLeX)-mediated adhesion of embryo cells to endometrium. May affect insulin signaling by up-regulating the phosphorylation and expression of some signaling molecules involved in the insulin-signaling pathway through SLe(x) which is present on the glycans of the INSRR alpha subunit (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.-;2.4.1.65;2.4.1.152", "go_molecular_function": "GO:0046920 alpha-(1->3)-fucosyltransferase activity;GO:0017083 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0022409 positive regulation of cell-cell adhesion;GO:1903238 positive regulation of leukocyte tethering or rolling;GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell;GO:0006954 inflammatory response;GO:0045785 positive regulation of cell adhesion", "synthesized_glycan_count": 556, "hit_score": 0.3, "record_id": "G3MZR2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G3N179-1", "uniprot_id": "G3N179_BOVIN", "mass": 55584.0, "length": 503, "protein_name": "Cystine/glutamate transporter", "gene_name": "SLC7A11", "organism": "Bovine", "refseq_name": "cystine/glutamate transporter", "refseq_ac": "XP_024833346", "gene_names_uniprotkb": "SLC7A11", "gene_names_refseq": "SLC7A11", "protein_names_uniprotkb": "Cystine/glutamate transporter; Amino acid transport system xc-; Solute carrier family 7 member 11; xCT", "protein_names_refseq": "cystine/glutamate transporter", "tax_id": 9913, "disease": "", "pathway": " (bta:524078); (R-BTA-352230)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015179 L-amino acid transmembrane transporter activity;GO:0015327 cystine:glutamate antiporter activity;GO:0015252 proton channel activity;GO:0022840 leak channel activity;GO:0140926 L-kynurenine transmembrane transporter activity", "go_cellular_component": "GO:0009986 cell surface;GO:0097449 astrocyte projection;GO:0005765 lysosomal membrane;GO:0031526 brush border membrane;GO:0031528 microvillus membrane", "go_biological_process": "GO:0009636 response to toxic substance;GO:0015811 L-cystine transport;GO:0035752 lysosomal lumen pH elevation;GO:0003333 amino acid transmembrane transport;GO:0110076 negative regulation of ferroptosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3N179-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G3N1U2-1", "uniprot_id": "G3N1U2_BOVIN", "mass": 18827.0, "length": 170, "protein_name": "small monomeric GTPase", "gene_name": "HRAS", "organism": "Bovine", "refseq_name": "GTPase HRas isoform 2", "refseq_ac": "NP_001229276", "gene_names_uniprotkb": "HRAS", "gene_names_refseq": "H-Ras; HRAS", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "GTPase HRas (Transforming protein p21) (H-Ras-1) (c-H-ras); GTPase HRas isoform 2; Harvey ras 1; p19 H-RasIDX protein; v-Ha-ras Harvey rat sarcoma viral oncogene homolog", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "16924412;17515880;21193465", "class_list": "", "function": "Activation of H-Ras and its downstream signaling pathway in the retina and its vasculature could be under the control of superoxide, and H-Ras activation in diabetes can be prevented by inhibiting superoxide accumulation. Publication Status: Online-Only, [RefSeq, PubMed]; Data demonstrate that H-Ras activation is important in the activation of the specific signaling events leading to the accelerated retinal capillary cell apoptosis in hyperglycemic conditions., [RefSeq, PubMed]; Thrombospondin 1, fibronectin, and vitronectin are differentially dependent upon RAS, ERK1/2, and p38 for induction of vascular smooth muscle cell chemotaxis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0005525 GTP binding;GO:0043495 protein-membrane adaptor activity;GO:0019003 GDP binding;GO:0003925 G protein activity;GO:0160185 phospholipase C activator activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005654 nucleoplasm;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0010629 negative regulation of gene expression;GO:0030335 positive regulation of cell migration;GO:0032956 regulation of actin cytoskeleton organization;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "G3N1U2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G3N341-1", "uniprot_id": "G3N341_BOVIN", "mass": 20911.0, "length": 201, "protein_name": "Twist-related protein 1", "gene_name": "TWIST1", "organism": "Bovine", "refseq_name": "twist-related protein 1", "refseq_ac": "NP_001178074", "gene_names_uniprotkb": "TWIST1", "gene_names_refseq": "TWIST1", "protein_names_uniprotkb": "Twist-related protein 1", "protein_names_refseq": "twist homolog 1; twist-related protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:782170); (R-BTA-9764725)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "21814570", "class_list": "", "function": "Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of pro-inflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-BMAL1 heterodimer., [UniProtKB, UniProtKB]; Frame-shift mutation in TWIST1 is associated with type 2 scurs syndrome., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019904 protein domain specific binding;GO:0042803 protein homodimerization activity;GO:0042826 histone deacetylase binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:2000780 negative regulation of double-strand break repair;GO:0060900 embryonic camera-type eye formation;GO:2000793 cell proliferation involved in heart valve development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "G3N341-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G3N3L0-1", "uniprot_id": "G3N3L0_BOVIN", "mass": 25797.0, "length": 232, "protein_name": "Noggin", "gene_name": "NOG", "organism": "Bovine", "refseq_name": "noggin", "refseq_ac": "XP_002695600", "gene_names_uniprotkb": "NOG", "gene_names_refseq": "NOG", "protein_names_uniprotkb": "Noggin", "protein_names_refseq": "noggin", "tax_id": 9913, "disease": "", "pathway": " (bta:538769); (R-BTA-201451)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0098793 presynapse", "go_biological_process": "GO:1904888 cranial skeletal system development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0008283 cell population proliferation;GO:0008542 visual learning;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G3N3L0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G5E5A9-1", "uniprot_id": "G5E5A9_BOVIN", "mass": 285247.0, "length": 2601, "protein_name": "Fibronectin", "gene_name": "FN1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FN1", "gene_names_refseq": "", "protein_names_uniprotkb": "Fibronectin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-114608); (R-BTA-1474228); (R-BTA-1566977); (R-BTA-202733); (R-BTA-216083); (R-BTA-3000170); (R-BTA-3000178); (R-BTA-354192); (R-BTA-354194); (R-BTA-372708); (R-BTA-381426); (R-BTA-5674135); (R-BTA-8874081); (R-BTA-8957275); (R-BTA-9634597); (R-BTA-9860927)", "pathway_count": 16, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Secreted by contracting muscle, induces liver autophagy, a degradative pathway for nutrient mobilization and damage removal, and systemic insulin sensitization via hepatic ITGA5:ITGB1 integrin receptor signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0002020 protease binding;GO:0005178 integrin binding;GO:0016504 peptidase activator activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0070062 extracellular exosome;GO:0016324 apical plasma membrane;GO:0005577 fibrinogen complex;GO:0005604 basement membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0006953 acute-phase response;GO:0008360 regulation of cell shape;GO:0071635 negative regulation of transforming growth factor beta production;GO:0051702 biological process involved in interaction with symbiont", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "G5E5A9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "G5E5X0-1", "uniprot_id": "LIMD1_BOVIN", "mass": 71885.0, "length": 674, "protein_name": "LIM domain-containing protein 1", "gene_name": "LIMD1", "organism": "Bovine", "refseq_name": "LIM domain-containing protein 1", "refseq_ac": "NP_001180092", "gene_names_uniprotkb": "LIMD1", "gene_names_refseq": "LIMD1", "protein_names_uniprotkb": "LIM domain-containing protein 1", "protein_names_refseq": "LIM domain-containing protein 1; LIM domains containing 1", "tax_id": 9913, "disease": "", "pathway": " (bta:617525); (R-BTA-1234176)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG-dependent repression of E-cadherin transcription. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1-responsive elements. Regulates osteoblast development, function, differentiation and stress osteoclastogenesis. Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1) and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts. May act as a tumor suppressor by inhibiting cell proliferation (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005912 adherens junction;GO:0005925 focal adhesion", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0001666 response to hypoxia;GO:0006355 regulation of DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "G5E5X0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O02691-1", "uniprot_id": "HCD2_BOVIN", "mass": 27140.0, "length": 261, "protein_name": "3-hydroxyacyl-CoA dehydrogenase type-2", "gene_name": "HSD17B10", "organism": "Bovine", "refseq_name": "3-hydroxyacyl-CoA dehydrogenase type-2", "refseq_ac": "NP_776759", "gene_names_uniprotkb": "HSD17B10; HADH2", "gene_names_refseq": "HADH2; HSD17B10; MHBD", "protein_names_uniprotkb": "3-hydroxyacyl-CoA dehydrogenase type-2; 1.1.1.159; 1.1.1.178; 1.1.1.239; 1.1.1.35; 1.1.1.53; 1.1.1.62; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; MHBD; Mitochondrial RNase P protein 2; Mitochondrial ribonuclease P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH", "protein_names_refseq": "17-beta-HSD 10; 17-beta-estradiol 17-dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 10; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3-hydroxyacyl-CoA dehydrogenase type-2; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; endoplasmic reticulum-associated amyloid beta-peptide-binding protein; hydroxyacyl-Coenzyme A dehydrogenase, type II hydroxyacyl-Coenzyme A; mitochondrial RNase P protein 2; mitochondrial ribonuclease P protein 2; short chain dehydrogenase/reductase family 5C member 1; short-chain type dehydrogenase/reductase XH98G2; type II HADH", "tax_id": 9913, "disease": "", "pathway": " (bta:281809); (R-BTA-70895); (R-BTA-9837999)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "9061028", "class_list": "", "function": "In addition to mitochondrial dehydrogenase activity, moonlights as a component of mitochondrial ribonuclease P, a complex that cleaves tRNA molecules in their 5'-ends. Together with TRMT10C/MRPP1, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity. The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 and m1A9, respectively) in tRNAs; HSD17B10/MRPP2 acting as a non-catalytic subunit. The MRPP1-MRPP2 subcomplex also acts as a tRNA maturation platform: following 5'-end cleavage by the mitochondrial ribonuclease P complex, the MRPP1-MRPP2 subcomplex enhances the efficiency of 3'-processing catalyzed by ELAC2, retains the tRNA product after ELAC2 processing and presents the nascent tRNA to the mitochondrial CCA tRNA nucleotidyltransferase TRNT1 enzyme. Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly., [UniProtKB, UniProtKB]; Mitochondrial dehydrogenase involved in pathways of fatty acid, branched-chain amino acid and steroid metabolism. Acts as (S)-3-hydroxyacyl-CoA dehydrogenase in mitochondrial fatty acid beta-oxidation, a major degradation pathway of fatty acids. Catalyzes the third step in the beta-oxidation cycle, namely the reversible conversion of (S)-3-hydroxyacyl-CoA to 3-ketoacyl-CoA. Preferentially accepts straight medium- and short-chain acyl-CoA substrates with highest efficiency for (3S)-hydroxybutanoyl-CoA. Acts as 3-hydroxy-2-methylbutyryl-CoA dehydrogenase in branched-chain amino acid catabolic pathway. Catalyzes the oxidation of 3-hydroxy-2-methylbutanoyl-CoA into 2-methyl-3-oxobutanoyl-CoA, a step in isoleucine degradation pathway. Has hydroxysteroid dehydrogenase activity toward steroid hormones and bile acids. Catalyzes the oxidation of 3alpha-, 17beta-, 20beta- and 21-hydroxysteroids and 7alpha- and 7beta-hydroxy bile acids. Oxidizes allopregnanolone/brexanolone at the 3alpha-hydroxyl group, which is known to be critical for the activation of gamma-aminobutyric acid receptors (GABAARs) chloride channel. Has phospholipase C-like activity toward cardiolipin and its oxidized species. Likely oxidizes the 2'-hydroxyl in the head group of cardiolipin to form a ketone intermediate that undergoes nucleophilic attack by water and fragments into diacylglycerol, dihydroxyacetone and orthophosphate. Has higher affinity for cardiolipin with oxidized fatty acids and may degrade these species during the oxidative stress response to protect cells from apoptosis. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD). Essential for structural and functional integrity of mitochondria., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2TBG6", "ec_number_list": "1.4.1.3;2.7.1.23;1.1.1.35;5.3.3.21;2.7.11.-;4.2.1.17;1.1.1.211;1.1.1.62;1.1.1.239;1.1.1.178;1.1.1.53;1.1.1.159;3.4.21.53;5.3.3.8;1.1.1.n12;2.3.1.41;1.1.1.330;6.1.1.5;3.5.3.1;5.6.1.7;7.1.2.2;1.1.1.-;1.1.1.357;1.1.1.188;1.1.1.64;1.1.1.210;2.3.1.168;2.3.1.-;1.2.4.1;7.1.1.2;1.2.1.3;4.2.1.3;4.98.1.1;1.1.1.225;1.1.1.209;1.1.1.51;1.3.8.5;1.2.4.2;1.1.1.315;2.3.3.1;2.3.1.9;2.3.3.10;6.4.1.3;1.1.1.37;1.1.1.105;3.6.4.10;1.3.8.1", "go_molecular_function": "GO:0000049 tRNA binding;GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity;GO:0047035 testosterone dehydrogenase (NAD+) activity;GO:0044594 17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0003857 (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0042645 mitochondrial nucleoid;GO:0030678 mitochondrial ribonuclease P complex", "go_biological_process": "GO:0008210 estrogen metabolic process;GO:0062173 brexanolone metabolic process;GO:0006631 fatty acid metabolic process;GO:0006635 fatty acid beta-oxidation;GO:0006699 bile acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O02691-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O02718-1", "uniprot_id": "BCL2_BOVIN", "mass": 25100.0, "length": 229, "protein_name": "Apoptosis regulator Bcl-2", "gene_name": "BCL2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "BCL2", "gene_names_refseq": "", "protein_names_uniprotkb": "Apoptosis regulator Bcl-2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "9501056", "class_list": "", "function": "Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). Also acts as an inhibitor of autophagy: interacts with BECN1 and AMBRA1 during non-starvation conditions and inhibits their autophagy function. May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015267 channel activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0016020 membrane;GO:0031965 nuclear membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0043066 negative regulation of apoptotic process;GO:0051881 regulation of mitochondrial membrane potential;GO:0006914 autophagy;GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O02718-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O02741-1", "uniprot_id": "ISG15_BOVIN", "mass": 17310.0, "length": 154, "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "ISG15", "organism": "Bovine", "refseq_name": "ubiquitin-like protein ISG15", "refseq_ac": "NP_776791", "gene_names_uniprotkb": "ISG15; G1P2; ISG17; UCRP", "gene_names_refseq": "ISG15", "protein_names_uniprotkb": "Ubiquitin-like protein ISG15; BoUCRP; Interferon-stimulated gene product 17; Ubiquitin cross-reactive protein", "protein_names_refseq": "boUCRP; interferon-stimulated gene product 17; interferon-stimulated protein, 15 kDa; ubiquitin cross-reactive protein; ubiquitin-like protein ISG15", "tax_id": 9913, "disease": "", "pathway": " (bta:281871); (R-BTA-1169408); (R-BTA-5656169); (R-BTA-936440); (R-BTA-9833482); (R-BTA-9909505)", "pathway_count": 6, "publication_count": 10, "publication_id_list": "10406469;14563704;22160940;23384108;27165775;27766692;27802914;8835381;9348245;9546718", "class_list": "", "function": "Bovine herpesvirus 1 protein bICP0 represses the transcription of bISG15 in fetal bovine lung cells., [RefSeq, PubMed]; Data indicate that the expression profiles of ISG15, MX1, MX2, and OAS1 could be a useful diagnostic biomarker of gestation. Publication Status: Online-Only, [RefSeq, PubMed]; Data suggest that ISG15 is involved in early blastocyst/embryo development; ISG15 appears to regulate gene expression in developing blastocyst; specifically, ISG15 is required for up-regulation of IFNT expression in blastocyst development. (ISG15 = ubiquitin-like protein ISG15, interferon-stimulated gene 15 protein; IFNT = interferon-tau), [RefSeq, PubMed]; ISG 15 gene expression is upregulated during 16-18 days of pregnancy and could be used as an early pregnancy marker in dairy cows, especially in heifers., [RefSeq, PubMed]; ISG15, UBE1l and UBCH8 genes are significantly upregulated in the artificially inseminated pregnant cows., [RefSeq, PubMed]; Interferon-stimulated protein(ISG15) was localized throughout the endometrium on day 18-23 of bovine pregnancy and was specifically localized to organelles and compartments of endometrial epithelial cells and stromal cells, [RefSeq, PubMed]; Ubiquitin-like protein which plays a key role in the innate immune response to viral infection either via its conjugation to a target protein (ISGylation) or via its action as a free or unconjugated protein. ISGylation involves a cascade of enzymatic reactions involving E1, E2, and E3 enzymes which catalyze the conjugation of ISG15 to a lysine residue in the target protein. Exhibits antiviral activity towards both DNA and RNA viruses. The secreted form of ISG15 can: induce natural killer cell proliferation, augment lymphokine-activated-killer (LAK) activity, induce dendritic cell maturation, act as a chemotactic factor for neutrophils and act as a IFN-gamma-inducing cytokine playing an essential role in antimycobacterial immunity (By similarity). The secreted form acts through the integrin ITGAL/ITGB2 receptor to initiate activation of SRC family tyrosine kinases including LYN, HCK and FGR which leads to secretion of IFNG and IL10; the interaction is mediated by ITGAL (By similarity). In response to IFN-tau secreted by the conceptus, may ligate to and regulate proteins involved in the release of prostaglandin F2-alpha (PGF), and thus prevent lysis of the corpus luteum and maintain the pregnancy (PubMed:9546718)., [UniProtKB, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3T0N6", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding;GO:0003735 structural constituent of ribosome;GO:0031386 protein tag activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0022626 cytosolic ribosome", "go_biological_process": "GO:0070585 protein localization to mitochondrion;GO:0007229 integrin-mediated signaling pathway;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0045071 negative regulation of viral genome replication", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "O02741-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O02755-1", "uniprot_id": "CEBPB_BOVIN", "mass": 36390.0, "length": 348, "protein_name": "CCAAT/enhancer-binding protein beta", "gene_name": "CEBPB", "organism": "Bovine", "refseq_name": "CCAAT/enhancer-binding protein beta", "refseq_ac": "NP_789745", "gene_names_uniprotkb": "CEBPB", "gene_names_refseq": "CEBPB", "protein_names_uniprotkb": "CCAAT/enhancer-binding protein beta; C/EBP beta", "protein_names_refseq": "CCAAT/enhancer binding protein (C/EBP), beta; CCAAT/enhancer-binding protein beta; c/EBP beta", "tax_id": 9913, "disease": "", "pathway": " (bta:338319)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "19845957;21255844;22738246;22748806;24327170;27333951;27439381;9051485", "class_list": "", "function": "Co-culture of adipocytes and myoblasts elicited an increase in C/EBPbeta and PPAR-gamma gene expression in differentiated myoblasts and an increase in GPR43 gene expression in adipocytes., [RefSeq, PubMed]; Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Also plays a significant role in adipogenesis, as well as in the gluconeogenic pathway, liver regeneration, and hematopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Its functional capacity is governed by protein interactions and post-translational protein modifications. During early embryogenesis, plays essential and redundant roles with CEBPA. Has a promitotic effect on many cell types such as hepatocytes and adipocytes but has an antiproliferative effect on T-cells by repressing MYC expression, facilitating differentiation along the T-helper 2 lineage. Binds to regulatory regions of several acute-phase and cytokines genes and plays a role in the regulation of acute-phase reaction and inflammation. Also plays a role in intracellular bacteria killing. During adipogenesis, is rapidly expressed and, after activation by phosphorylation, induces CEBPA and PPARG, which turn on the series of adipocyte genes that give rise to the adipocyte phenotype. The delayed transactivation of the CEBPA and PPARG genes by CEBPB appears necessary to allow mitotic clonal expansion and thereby progression of terminal differentiation. Essential for female reproduction because of a critical role in ovarian follicle development. Restricts osteoclastogenesis: together with NFE2L1; represses expression of DSPP during odontoblast differentiation (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Interaction of C/EBP-beta and NF-Y factors constrains activity levels of the nutritionally controlled promoter IA expressing the acetyl-CoA carboxylase-alpha gene in cattle. Publication Status: Online-Only, [RefSeq, PubMed]; SREBP1a activated while C/EBP factors downregulated the activity of the SCD1 promoter. Publication Status: Online-Only, [RefSeq, PubMed]; Suppression of CPT1B and induction of SCD and CEBPB by supplemental arginine promotes increased adiposity in Angus steers., [RefSeq, PubMed]; The 3' terminal end of the first intron of porcine SPP1 harbors a C/EBPbeta binding site and this binding site is negatively affected by the mutant G allele. Publication Status: Online-Only, [RefSeq, PubMed]; The role of NF-kappaB and C/EBP factors in regulating basal and pathogen-induced expression of both genes from cattle, is investigated., [RefSeq, PubMed]; These results indicate that the C/EBPbeta gene plays an important regulatory role in regulation of the cell cycle regulators and spermatogenesis-related genes expression and function of bovine SCs., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0042803 protein homodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0072574 hepatocyte proliferation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "O02755-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O02776-1", "uniprot_id": "PARG_BOVIN", "mass": 110837.0, "length": 977, "protein_name": "Poly(ADP-ribose) glycohydrolase", "gene_name": "PARG", "organism": "Bovine", "refseq_name": "poly(ADP-ribose) glycohydrolase", "refseq_ac": "NP_776563", "gene_names_uniprotkb": "PARG", "gene_names_refseq": "PARG", "protein_names_uniprotkb": "Poly(ADP-ribose) glycohydrolase; 3.2.1.143", "protein_names_refseq": "poly(ADP-ribose) glycohydrolase", "tax_id": 9913, "disease": "", "pathway": " (bta:281377)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15658938;9115250", "class_list": "", "function": "Poly(ADP-ribose) glycohydrolase that degrades poly(ADP-ribose) by hydrolyzing the ribose-ribose bonds present in poly(ADP-ribose) (PubMed:15658938). PARG acts both as an endo- and exoglycosidase, releasing poly(ADP-ribose) of different length as well as ADP-ribose monomers. It is however unable to cleave the ester bond between the terminal ADP-ribose and ADP-ribosylated residues, leaving proteins that are mono-ADP-ribosylated. Poly(ADP-ribose) is synthesized after DNA damage is only present transiently and is rapidly degraded by PARG. Required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress, while it is not required for recovery from transient replicative stress. Responsible for the prevalence of mono-ADP-ribosylated proteins in cells, thanks to its ability to degrade poly(ADP-ribose) without cleaving the terminal protein-ribose bond. Required for retinoid acid-dependent gene transactivation, probably by removing poly(ADP-ribose) from histone demethylase KDM4D, allowing chromatin derepression at RAR-dependent gene promoters. Involved in the synthesis of ATP in the nucleus, together with PARP1, NMNAT1 and NUDT5. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.2.1.143;3.5.1.-;3.2.2.-", "go_molecular_function": "GO:0004649 poly(ADP-ribose) glycohydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0006974 DNA damage response;GO:0009225 nucleotide-sugar metabolic process;GO:0006282 regulation of DNA repair;GO:1990966 ATP generation from poly-ADP-D-ribose", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "O02776-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O02853-1", "uniprot_id": "PTGDS_BOVIN", "mass": 21229.0, "length": 191, "protein_name": "Prostaglandin-H2 D-isomerase", "gene_name": "PTGDS", "organism": "Bovine", "refseq_name": "prostaglandin-H2 D-isomerase precursor", "refseq_ac": "NP_777216", "gene_names_uniprotkb": "PTGDS", "gene_names_refseq": "PTGDS", "protein_names_uniprotkb": "Prostaglandin-H2 D-isomerase; 5.3.99.2; Glutathione-independent PGD synthase; Lipocalin-type prostaglandin-D synthase; PGD2 synthase; PGDS2; PGDS; Prostaglandin-D2 synthase", "protein_names_refseq": "PGD2 synthase; PGDS2; PGDS; glutathione-independent PGD synthase; glutathione-independent PGD synthetase; lipocalin-type prostaglandin-D synthase; prostaglandin D2 synthase 21kDa (brain); prostaglandin-H2 D-isomerase precursor; prostaglandin-H2 D-isomerase", "tax_id": 9913, "disease": "", "pathway": " (bta:286858); (R-BTA-2162123)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10684794;11804963;18272301;9510973", "class_list": "", "function": "Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation (PubMed:9510973). Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system (By similarity). Involved in PLA2G3-dependent maturation of mast cells. PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB]; L-PGDS may have a role in cattle fertilization., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A2VDW5;A5PJE8", "ec_number_list": "5.3.99.2;2.5.1.18", "go_molecular_function": "GO:0004667 prostaglandin-D synthase activity;GO:0036094 small molecule binding;GO:0005501 retinoid binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005791 rough endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0031965 nuclear membrane", "go_biological_process": "GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:0045071 negative regulation of viral genome replication;GO:0044793 host-mediated suppression of viral proces;GO:0001516 prostaglandin biosynthetic process;GO:0043303 mast cell degranulation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "O02853-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O18756-1", "uniprot_id": "GLCE_BOVIN", "mass": 69985.0, "length": 617, "protein_name": "D-glucuronyl C5-epimerase", "gene_name": "GLCE", "organism": "Bovine", "refseq_name": "D-glucuronyl C5-epimerase", "refseq_ac": "NP_776495", "gene_names_uniprotkb": "GLCE", "gene_names_refseq": "GLCE", "protein_names_uniprotkb": "D-glucuronyl C5-epimerase; 5.1.3.17; Heparan sulfate C5-epimerase; Heparin/heparan sulfate:glucuronic acid C5-epimerase; Heparosan-N-sulfate-glucuronate 5-epimerase; Hsepi", "protein_names_refseq": "D-glucuronyl C5-epimerase; glucuronyl C5-epimerase; heparan sulfate C5-epimerase; heparin/heparan sulfate:glucuronic acid C5-epimerase; heparosan-N-sulfate-glucuronate 5-epimerase; hsepi", "tax_id": 9913, "disease": "", "pathway": " (bta:281195)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10727403;11274177;30573663;9346972", "class_list": "", "function": "Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.1.3.17", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0005509 calcium ion binding;GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0030210 heparin proteoglycan biosynthetic process;GO:0015012 heparan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "O18756-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O18836-1", "uniprot_id": "GDF8_BOVIN", "mass": 42551.0, "length": 375, "protein_name": "Growth/differentiation factor 8", "gene_name": "MSTN", "organism": "Bovine", "refseq_name": "growth/differentiation factor 8 precursor", "refseq_ac": "NP_001001525", "gene_names_uniprotkb": "MSTN; GDF8; MH", "gene_names_refseq": "GDF8; MSTN", "protein_names_uniprotkb": "Growth/differentiation factor 8; GDF-8; Myostatin", "protein_names_refseq": "GDF-8; growth/differentiation factor 8 precursor; growth/differentiation factor 8", "tax_id": 9913, "disease": "", "pathway": " (bta:281187)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "11451380;15975431;16110474;31987910;32210722;32564663;32841375;37175828;9314496;9356471", "class_list": "", "function": "Acts specifically as a negative regulator of skeletal muscle growth., [UniProtKB, UniProtKB]; Association between polymorphisms of Myf5, MSTN and CAST genes and fattening performance in Brown Swiss and Holstein cattle breeds., [RefSeq, PubMed]; Combined Transcriptome and Metabolome Analysis of Smooth Muscle of Myostatin Knockout Cattle. Publication Status: Online-Only, [RefSeq, PubMed]; Identified conserved polymorphisms in coding and non-coding regions of bovine MSTN gene. Variations in MSTN might affect growth and carcass traits in NZ cattle., [RefSeq, PubMed]; MSTN Mutant Promotes Myogenic Differentiation by Increasing Demethylase TET1 Expression via the SMAD2/SMAD3 Pathway. Publication Status: Online-Only, [RefSeq, PubMed]; Myostatin site-directed mutation and simultaneous PPARgamma site-directed knockin in bovine genome., [RefSeq, PubMed]; Northern blot analysis revealed no appreciable change in myostatin mRNA levels between proliferating myoblasts and differentiated myotubes., [RefSeq, PubMed]; Results suggest that myostatin auto-regulates its gene expression through a Smad7 dependent mechanism in myogenic cells., [RefSeq, PubMed]; This gene encodes a member of the TGF-beta (transforming growth factor-beta) family of proteins. The encoded preproprotein is proteolytically processed to generate an N-terminal propeptide and a C-terminal subunit. The C-terminal subunits form the mature homodimer, which negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jun 2016]., [RefSeq]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A4IFF8;O18829;Q564D4;Q8WNS6;Q95N97", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0005125 cytokine activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0014816 skeletal muscle satellite cell differentiation;GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0046716 muscle cell cellular homeostasis;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "O18836-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O18956-1", "uniprot_id": "ENTP1_BOVIN", "mass": 58114.0, "length": 513, "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 1", "gene_name": "ENTPD1", "organism": "Bovine", "refseq_name": "ectonucleoside triphosphate diphosphohydrolase 1", "refseq_ac": "NP_776961", "gene_names_uniprotkb": "ENTPD1; CD39", "gene_names_refseq": "ATP-DPH; ENTPD1", "protein_names_uniprotkb": "Ectonucleoside triphosphate diphosphohydrolase 1; 3.6.1.5; ATP diphosphohydrolase; ATP-DPH; ATPDase; Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; NTPDase1; Nucleoside triphosphate diphosphohydrolase 1", "protein_names_refseq": "ATPDase; NTPDase 1; NTPDase1; ecto-ATP diphosphohydrolase 1; ecto-ATPDase 1; ecto-ATPase 1; ecto-apyrase; ectonucleoside triphosphate diphosphohydrolase 1; lymphoid cell activation antigen; nucleoside triphosphate diphosphohydrolase 1", "tax_id": 9913, "disease": "", "pathway": " (bta:282223)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8955160", "class_list": "", "function": "Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs) (By similarity). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates (By similarity). This activity contributes to the regulation of extracellular levels of nucleotides (By similarity). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.5.5;3.6.4.6;3.6.4.10;3.6.1.6;5.6.2.3;3.6.5.-;3.6.5.3;3.6.1.64;3.6.1.62;5.6.2.-;2.7.4.3;3.6.4.-;3.6.1.16;3.6.1.53;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.6.5.4;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0016887 ATP hydrolysis activity;GO:0004382 GDP phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005901 caveola", "go_biological_process": "GO:0070527 platelet aggregation;GO:0009134 nucleoside diphosphate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O18956-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O18963-1", "uniprot_id": "CP2E1_BOVIN", "mass": 56827.0, "length": 495, "protein_name": "Cytochrome P450 2E1", "gene_name": "CYP2E1", "organism": "Bovine", "refseq_name": "cytochrome P450 2E1", "refseq_ac": "NP_776955", "gene_names_uniprotkb": "CYP2E1; CYP2E", "gene_names_refseq": "CYP2E1; CYPIIE1", "protein_names_uniprotkb": "Cytochrome P450 2E1; 1.14.13.n7; 1.14.14.1; 4-nitrophenol 2-hydroxylase; CYPIIE1", "protein_names_refseq": "4-nitrophenol 2-hydroxylase; cytochrome P450 2E1; cytochrome P450, family 2, subfamily E, polypeptide 1; cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1", "tax_id": 9913, "disease": "", "pathway": " (bta:282213)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q4PS78", "ec_number_list": "1.14.14.-;1.14.13.n7;1.14.14.1", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0051879 Hsp90 protein binding;GO:0030544 Hsp70 protein binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005743 mitochondrial inner membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0019373 epoxygenase P450 pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "O18963-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O18971-1", "uniprot_id": "PPARG_BOVIN", "mass": 57579.0, "length": 505, "protein_name": "Peroxisome proliferator-activated receptor gamma", "gene_name": "PPARG", "organism": "Bovine", "refseq_name": "peroxisome proliferator-activated receptor gamma", "refseq_ac": "NP_851367", "gene_names_uniprotkb": "PPARG; NR1C3", "gene_names_refseq": "PPARG", "protein_names_uniprotkb": "Peroxisome proliferator-activated receptor gamma; Nuclear receptor subfamily 1 group C member 3; PPAR-gamma", "protein_names_refseq": "PPAR-gamma; nuclear receptor subfamily 1 group C member 3; peroxisome proliferative activated receptor, gamma; peroxisome proliferator activated receptor gamma 2; peroxisome proliferator-activated receptor gamma", "tax_id": 9913, "disease": "", "pathway": " (bta:281993); (R-BTA-381340); (R-BTA-383280); (R-BTA-9841922)", "pathway_count": 4, "publication_count": 8, "publication_id_list": "15111490;16595010;30336279;30599237;31223619;32841375;33052678;9367859", "class_list": "", "function": "Bovine Stearoyl-CoA Desaturase 1 Promotes Adipogenesis by Activating the PPARgamma Receptor., [RefSeq, PubMed]; Ligand-activated transcription factor that forms obligate heterodimers with the retinoic acid receptor and acts as a key regulator of biological processes, such as adipocyte differentiation, lipid metabolism, glucose homeostasis and beta-oxidation of fatty acids. Activated by lipid ligands: binds peroxisome proliferators, such as hypolipidemic drugs, and fatty acids, such as prostaglandin J2 metabolites. Ligand-binding results in a conformational change in the receptor, promoting dissociation of repressors and recruitment of coactivators, and subsequent activation of target gene expression. Specifically binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase (By similarity). Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated pro-inflammatory responses (By similarity). Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of BMAL1 in the blood vessels (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; MTORC2 plays a critical role in regulating lipogenic gene expression, lipid synthesis, and secretion in bovine mammary epithelial cells, and this process probably is through PPARgamma. Publication Status: Online-Only, [RefSeq, PubMed]; Myostatin site-directed mutation and simultaneous PPARgamma site-directed knockin in bovine genome., [RefSeq, PubMed]; Nuclear receptor that acts as the key factor controlling the development of adipocytes. Specifically activated by 15-deoxy-delta12,14-prostaglandin J2 ligand during early adipogenesis, driving differentiation of all types of adipocytes (white, beige and brown). Acts together with retinoic acid receptor RXRA, forming the ARF6 complex, which acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Following recruitment of TLE3, promotes differentiation of white adipocytes. Following recruitment of PRDM16, promotes differentiation of myoblastic precursors into brown adipose cells (BAT), which are specialized in dissipating energy in the form of heat in response to cold or excess feeding. Also mediates diffentiation of white adipocytes into beige adipocytes by mediating recruitment of PRDM16., [UniProtKB, UniProtKB]; PPARgamma1 has bifunctional properties in the regulation of KDR gene expression mediated via interaction with both Sp1 and Sp3, [RefSeq, PubMed]; Results found that PPAR-gamma expression is regulated by miR-454 in bovine mammary epithelial cells (BMECs). miR-454 directly targets the 3'UTR of PPAR-gamma to regulate triglyceride synthesis in BMECs., [RefSeq, PubMed]; There is evidence of cotranscription and intergenic splicing events between the PPARG gene and the neighboring gene TSEN2 in cattle. Two types of chimeric transcripts are observed. Publication Status: Online-Only, [RefSeq, PubMed]; This study shows that bta-miR-130a and bta-miR-130b play similar roles in the regulation of adipocyte differentiation in beef muscles by targeting the 3'UTR of PPARG and CYP2U1., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q1LZB7;Q8HY47", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006631 fatty acid metabolic process;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "O18971-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O19116-1", "uniprot_id": "SFRP1_BOVIN", "mass": 34763.0, "length": 308, "protein_name": "Secreted frizzled-related protein 1", "gene_name": "SFRP1", "organism": "Bovine", "refseq_name": "secreted frizzled-related protein 1 precursor", "refseq_ac": "NP_776885", "gene_names_uniprotkb": "SFRP1; FRZA", "gene_names_refseq": "SFRP1", "protein_names_uniprotkb": "Secreted frizzled-related protein 1; Frizzled in aorta protein; FrzA protein; sFRP-1", "protein_names_refseq": "frizzled in aorta protein; frzA protein; sFRP-1; secreted frizzled-related protein 1 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:282068)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "10381896", "class_list": "", "function": "Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005109 frizzled binding;GO:0017147 Wnt-protein binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0030036 actin cytoskeleton organization;GO:0051496 positive regulation of stress fiber assembly;GO:0034446 substrate adhesion-dependent cell spreading;GO:0051894 positive regulation of focal adhesion assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O19116-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O19131-1", "uniprot_id": "TNR1A_BOVIN", "mass": 51368.0, "length": 471, "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "organism": "Bovine", "refseq_name": "tumor necrosis factor receptor superfamily member 1A precursor", "refseq_ac": "NP_777099", "gene_names_uniprotkb": "TNFRSF1A; TNFR1", "gene_names_refseq": "TNFRSF1A", "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member 1A; TNF-R1; TNF-RI; TNFR-I; Tumor necrosis factor receptor 1; Tumor necrosis factor receptor type I; p55; p60", "protein_names_refseq": "TNF-R1; TNF-RI; TNFR-I; p55; p60; tumor necrosis factor receptor 1; tumor necrosis factor receptor superfamily member 1A precursor; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type I", "tax_id": 9913, "disease": "", "pathway": " (bta:282527)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15310755;20562522;20705117;21551345;9613449", "class_list": "", "function": "Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity)., [UniProtKB]; TNF binding induces release of AIP1 (DAB2IP) from TNFR1, resulting in cytoplasmic translocation and concomitant formation of an intracellular signaling complex comprised of TRADD, RIP1, TRAF2, and AIPl., [RefSeq, PubMed]; The expression and cellular localization of tumor necrosis factor-alpha (TNF) and its receptors (TNFRI and TNFRII) mRNAs and proteins, were determined., [RefSeq, PubMed]; The upregulation of TNFRI mRNA expression by IFNG suggests that TNF and IFNG synergistically affect the death of luteal endothelial cells resulting in acute luteolysis, [RefSeq, PubMed]; These results suggest that TNF-alpha sources include immune cells, as well as large and small luteal cells, and that TNF-RI and TNF-RII are present in the luteal cells of the bovine corpus luteum., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q2HJ72", "ec_number_list": "", "go_molecular_function": "GO:0043120 tumor necrosis factor binding;GO:0005031 tumor necrosis factor receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0043235 receptor complex;GO:0045121 membrane raft", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0006952 defense response;GO:0006954 inflammatory response;GO:0007166 cell surface receptor signaling pathway;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "O19131-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O46382-1", "uniprot_id": "BIG1_BOVIN", "mass": 208712.0, "length": 1849, "protein_name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 1", "gene_name": "ARFGEF1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ARFGEF1; ARFGEP1; BIG1", "gene_names_refseq": "", "protein_names_uniprotkb": "Brefeldin A-inhibited guanine nucleotide-exchange protein 1; ADP-ribosylation factor guanine nucleotide-exchange factor 1; Brefeldin A-inhibited GEP 1; p200 ARF guanine nucleotide exchange factor; p200 ARF-GEP1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:281022)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "8917509;9371777", "class_list": "", "function": "Promotes guanine-nucleotide exchange on ARF1 and ARF3. Promotes the activation of ARF1/ARF3 through replacement of GDP with GTP. Involved in vesicular trafficking. Required for the maintenance of Golgi structure; the function may be independent of its GEF activity. Required for the maturation of integrin beta-1 in the Golgi. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. Proposed to act as A kinase-anchoring protein (AKAP) and may mediate crosstalk between Arf and PKA pathways. Inhibits GAP activity of MYO9B probably through competitive RhoA binding. The function in the nucleus remains to be determined (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0034237 protein kinase A regulatory subunit binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0016363 nuclear matrix", "go_biological_process": "GO:0015031 protein transport;GO:0009101 glycoprotein biosynthetic process;GO:0090303 positive regulation of wound healing;GO:0016192 vesicle-mediated transport;GO:0034260 negative regulation of GTPase activity", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "O46382-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O46600-1", "uniprot_id": "GHR_BOVIN", "mass": 70901.0, "length": 634, "protein_name": "Growth hormone receptor", "gene_name": "GHR", "organism": "Bovine", "refseq_name": "growth hormone receptor precursor", "refseq_ac": "NP_788781", "gene_names_uniprotkb": "GHR", "gene_names_refseq": "GHR", "protein_names_uniprotkb": "Growth hormone receptor; GH receptor; Serum-binding protein; Somatotropin receptor", "protein_names_refseq": "GH receptor; growth hormone receptor precursor; somatotropin receptor", "tax_id": 9913, "disease": "", "pathway": " (bta:280805)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10376317;11255006;2289631;25927168;27865414;29448132;29926362;31785637;9710756", "class_list": "", "function": "Comparatively studied genetic diversity of growth hormone receptor (GHR) in Tibetan cattle and Chinese Holstein cow., [RefSeq, PubMed]; Most heifer reproductive traits were not significantly affected by CAST and CAPN1 markers that are widely used to improve beef tenderness by selection and breeders should not be concerned with how these markers affect reproduction and other heifer traits with the possible exception of CAPN1 effects on calving date., [RefSeq, PubMed]; Receptor for pituitary gland growth hormone (GH1) involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway., [UniProtKB, UniProtKB]; Rs41639262 associated with fertility in hot-humid climate, [RefSeq, PubMed]; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling., [UniProtKB, UniProtKB]; There was no association between the genotypes of GH and IGF-IS and fertility of Holstein cows raised in semiextensive or intensive regimes, while the STAT5 ABstEII polymorphism was associated with calving-first heat interval in Holstein cows raised in the intensive system., [RefSeq, PubMed]; This study showed that the IGF-1 SnaBI TT appears to be associated with fewer days to ovulation and lesser calving to conseption interval of lactating dairy cows and had an additive association with the GHR AluI T allele on indicators for improvement of fertility., [RefSeq, PubMed]", "predicted_glycosites": 7, "predicted_n_glycosites": 6, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "O77538;Q5XM78;Q9TQV9;Q9TUY7", "ec_number_list": "", "go_molecular_function": "GO:0017046 peptide hormone binding;GO:0019955 cytokine binding;GO:0004903 growth hormone receptor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005829 cytosol;GO:0016020 membrane;GO:0009897 external side of plasma membrane;GO:0070195 growth hormone receptor complex", "go_biological_process": "GO:0006897 endocytosis;GO:0008284 positive regulation of cell population proliferation;GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT;GO:0019221 cytokine-mediated signaling pathway;GO:0060396 growth hormone receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "O46600-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O46631-1", "uniprot_id": "SHPS1_BOVIN", "mass": 55093.0, "length": 506, "protein_name": "Tyrosine-protein phosphatase non-receptor type substrate 1", "gene_name": "SIRPA", "organism": "Bovine", "refseq_name": "tyrosine-protein phosphatase non-receptor type substrate 1 precursor", "refseq_ac": "NP_786982", "gene_names_uniprotkb": "SIRPA; MYD1; PTPNS1; SHPS1; SIRP", "gene_names_refseq": "MYD-1; PTPNS1; SIRPA", "protein_names_uniprotkb": "Tyrosine-protein phosphatase non-receptor type substrate 1; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; MyD-1 antigen; SHP substrate 1; SHPS-1; Signal-regulatory protein alpha-1; Sirp-alpha-1", "protein_names_refseq": "CD172 antigen-like family member A; MyD-1 antigen; SHP substrate 1; SHPS-1; inhibitory receptor SHPS-1; protein tyrosine phosphatase, non-receptor type substrate 1; signal-regulatory protein alpha-1; sirp-alpha-1; tyrosine-protein phosphatase non-receptor type substrate 1 precursor; tyrosine-protein phosphatase non-receptor type substrate 1", "tax_id": 9913, "disease": "", "pathway": " (bta:327666)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "9485180", "class_list": "", "function": "Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Plays a role in antiviral immunity and limits new world arenavirus infection by decreasing virus internalization (By similarity). Receptor for THBS1 (By similarity). Interaction with THBS1 stimulates phosphorylation of SIRPA (By similarity). In response to THBS1, involved in ROS signaling in non-phagocytic cells, stimulating NADPH oxidase-derived ROS production (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 13, "predicted_n_glycosites": 13, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "O46632", "ec_number_list": "", "go_molecular_function": "GO:0017124 SH3 domain binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0050766 positive regulation of phagocytosis;GO:0050870 positive regulation of T cell activation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O46631-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O62654-1", "uniprot_id": "DESM_BOVIN", "mass": 53532.0, "length": 470, "protein_name": "Desmin", "gene_name": "DES", "organism": "Bovine", "refseq_name": "desmin", "refseq_ac": "NP_001075044", "gene_names_uniprotkb": "DES", "gene_names_refseq": "DES", "protein_names_uniprotkb": "Desmin", "protein_names_refseq": "desmin", "tax_id": 9913, "disease": "", "pathway": " (bta:280765); (R-BTA-390522)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "17927910", "class_list": "", "function": "Muscle-specific type III intermediate filament essential for proper muscular structure and function. Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction. Required for nuclear membrane integrity, via anchoring at the cell tip and nuclear envelope, resulting in maintenance of microtubule-derived intracellular mechanical forces (By similarity). Contributes to the transcriptional regulation of the NKX2-5 gene in cardiac progenitor cells during a short period of cardiomyogenesis and in cardiac side population stem cells in the adult. Plays a role in maintaining an optimal conformation of nebulette (NEB) on heart muscle sarcomeres to bind and recruit cardiac alpha-actin., [UniProtKB, UniProtKB, UniProtKB]; Results show that expression of desmin increased during the late fattening stage of of hanwoo steers and it contributes to the muscle contractile apparatus., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2VDU8;O62655", "ec_number_list": "", "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0042802 identical protein binding;GO:0008092 cytoskeletal protein binding", "go_cellular_component": "GO:0051286 cell tip;GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005911 cell-cell junction", "go_biological_process": "GO:0060538 skeletal muscle organ development;GO:0045109 intermediate filament organization;GO:0006998 nuclear envelope organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O62654-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O62698-1", "uniprot_id": "PGH2_BOVIN", "mass": 69163.0, "length": 604, "protein_name": "Prostaglandin G/H synthase 2", "gene_name": "PTGS2", "organism": "Bovine", "refseq_name": "prostaglandin G/H synthase 2 precursor", "refseq_ac": "NP_776870", "gene_names_uniprotkb": "PTGS2; COX2", "gene_names_refseq": "PTGS2", "protein_names_uniprotkb": "Prostaglandin G/H synthase 2; 1.14.99.1; COX-2; Cyclooxygenase-2; PGH synthase 2; PGHS-2; PHS II; Prostaglandin H2 synthase 2; Prostaglandin-endoperoxide synthase 2", "protein_names_refseq": "COX-2; PGH synthase 2; PGHS-2; PHS II; cyclooxygenase-2; prostaglandin G/H synthase 2 precursor; prostaglandin G/H synthase 2; prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)", "tax_id": 9913, "disease": "", "pathway": " (bta:282023)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "11207216;24186266;24852076;25007867;28244342;29033117;9348208", "class_list": "", "function": "Data suggested that PTGS-2 gene expression was induced by PTGER2 activation through the PKA and ERK pathways., [RefSeq, PubMed]; Dual cyclooxygenase and peroxidase in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate ((5Z,8Z,11Z,14Z)-eicosatetraenoate, AA, C20:4(n-6)), with a particular role in the inflammatory response. The cyclooxygenase activity oxygenates AA to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and the peroxidase activity reduces PGG2 to the hydroxy endoperoxide prostaglandin H2 (PGH2), the precursor of all 2-series prostaglandins and thromboxanes. This complex transformation is initiated by abstraction of hydrogen at carbon 13 (with S-stereochemistry), followed by insertion of molecular O2 to form the endoperoxide bridge between carbon 9 and 11 that defines prostaglandins. The insertion of a second molecule of O2 (bis-oxygenase activity) yields a hydroperoxy group in PGG2 that is then reduced to PGH2 by two electrons. Similarly catalyzes successive cyclooxygenation and peroxidation of dihomo-gamma-linoleate (DGLA, C20:3(n-6)) and eicosapentaenoate (EPA, C20:5(n-3)) to corresponding PGH1 and PGH3, the precursors of 1- and 3-series prostaglandins. In an alternative pathway of prostanoid biosynthesis, converts 2-arachidonoyl lysophopholipids to prostanoid lysophopholipids, which are then hydrolyzed by intracellular phospholipases to release free prostanoids. Metabolizes 2-arachidonoyl glycerol yielding the glyceryl ester of PGH2, a process that can contribute to pain response. Generates lipid mediators from n-3 and n-6 polyunsaturated fatty acids (PUFAs) via a lipoxygenase-type mechanism. Oxygenates PUFAs to hydroperoxy compounds and then reduces them to corresponding alcohols. Plays a role in the generation of resolution phase interaction products (resolvins) during both sterile and infectious inflammation. Metabolizes docosahexaenoate (DHA, C22:6(n-3)) to 17R-HDHA, a precursor of the D-series resolvins (RvDs). As a component of the biosynthetic pathway of E-series resolvins (RvEs), converts eicosapentaenoate (EPA, C20:5(n-3)) primarily to 18S-HEPE that is further metabolized by ALOX5 and LTA4H to generate 18S-RvE1 and 18S-RvE2. In vascular endothelial cells, converts docosapentaenoate (DPA, C22:5(n-3)) to 13R-HDPA, a precursor for 13-series resolvins (RvTs) shown to activate macrophage phagocytosis during bacterial infection. In activated leukocytes, contributes to oxygenation of hydroxyeicosatetraenoates (HETE) to diHETES (5,15-diHETE and 5,11-diHETE). Can also use linoleate (LA, (9Z,12Z)-octadecadienoate, C18:2(n-6)) as substrate and produce hydroxyoctadecadienoates (HODEs) in a regio- and stereospecific manner, being (9R)-HODE ((9R)-hydroxy-(10E,12Z)-octadecadienoate) and (13S)-HODE ((13S)-hydroxy-(9Z,11E)-octadecadienoate) its major products (By similarity). During neuroinflammation, plays a role in neuronal secretion of specialized preresolving mediators (SPMs) 15R-lipoxin A4 that regulates phagocytic microglia (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Exposure to follicular fluid transiently increased the transcript levels of IL8 and PTGS2, and decreased the expression of SOD2, GPX3, DAB2, and NR3C1. TNF and IL6 levels were also decreased while those of NAMPT were unaffected., [RefSeq, PubMed]; Results indicate that nuclear receptor subfamily 1 group D member 1(REV-ERBalpha) plays an inhibitory role in the expression of prostaglandin-endoperoxide synthase 2(PTGS2) in both bovine USCs and UECs treated with ovarian steroids, [RefSeq, PubMed]; The objective of this study was to evaluate the mRNA expression of prostaglandin-endoperoxide synthase 2 (PTGS 2), prostaglandin F2alpha synthase (PTGFS) and prostaglandin E2 microsomal synthase 1 (mPTGES 1) in the endometrium of repeat-breeding cows with and without subclinical endometritis., [RefSeq, PubMed]; This study showed that neutrophils from periparturient heifers show impairment of COX-2 mRNA expression and lactoferrin, suggesting that these mechanisms may contribute to immunosuppression in cows around calving., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "O46517;O62665", "ec_number_list": "4.2.1.152;5.3.99.5;1.14.99.1;5.3.99.4", "go_molecular_function": "GO:0004666 prostaglandin-endoperoxide synthase activity;GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0004601 peroxidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005789 endoplasmic reticulum membrane;GO:0043005 neuron projection;GO:0005637 nuclear inner membrane;GO:0005640 nuclear outer membrane", "go_biological_process": "GO:0001934 positive regulation of protein phosphorylation;GO:0006979 response to oxidative stress;GO:0040019 positive regulation of embryonic development;GO:0019371 cyclooxygenase pathway;GO:0071347 cellular response to interleukin-1", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "O62698-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O77627-1", "uniprot_id": "JUN_BOVIN", "mass": 36084.0, "length": 335, "protein_name": "Transcription factor Jun", "gene_name": "JUN", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "JUN", "gene_names_refseq": "", "protein_names_uniprotkb": "Transcription factor Jun; AP1; Activator protein 1; Proto-oncogene c-Jun; Transcription factor AP-1 subunit Jun; V-jun avian sarcoma virus 17 oncogene homolog", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor that recognizes and binds to the AP-1 consensus motif 5'-TGA[GC]TCA-3'. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to the AP-1 consensus sequence 5'-TGA[GC]TCA-3' and enhancing its transcriptional activity (By similarity). Together with FOSB, plays a role in activation-induced cell death of T cells by binding to the AP-1 promoter site of FASLG/CD95L, and inducing its transcription in response to activation of the TCR/CD3 signaling pathway (By similarity). Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28. Binds to the USP28 promoter., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0005096 GTPase activator activity;GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0017053 transcription repressor complex;GO:0005667 transcription regulator complex;GO:0000791 euchromatin;GO:0035976 transcription factor AP-1 complex", "go_biological_process": "GO:0019046 release from viral latency;GO:0006351 DNA-templated transcription;GO:0042127 regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007254 JNK cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "O77627-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O77656-1", "uniprot_id": "MMP13_BOVIN", "mass": 53921.0, "length": 471, "protein_name": "Collagenase 3", "gene_name": "MMP13", "organism": "Bovine", "refseq_name": "collagenase 3 precursor", "refseq_ac": "NP_776814", "gene_names_uniprotkb": "MMP13", "gene_names_refseq": "MMP13", "protein_names_uniprotkb": "Collagenase 3; 3.4.24.-; MMP-13; Matrix metalloproteinase-13", "protein_names_refseq": "MMP-13; collagenase 3 precursor; collagenase 3; matrix metalloproteinase 13 (collagenase 3); matrix metalloproteinase-13", "tax_id": 9913, "disease": "", "pathway": " (bta:281914)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "14660626;15115716;17306969;18589731;20463008;22688963", "class_list": "", "function": "At high but naturally occurring concentrations the collagen peptide CB12-II induced an increase in the expressions of MMP-13 and cleavage of type II collagen by collagenase in the mid zone and also in the superficial zone., [RefSeq, PubMed]; Increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 and MMP-13 (follicular apex vs. base) for the preovulatory collagenolysis required for follicle rupture, [RefSeq, PubMed]; MMP-13 and collagenase have roles in chondrocyte hypertrophy induced by type II collagen, [RefSeq, PubMed]; MMP-13 treatment of fresh articular cartilage results in cleaved fibromodulin fragments, [RefSeq, PubMed]; P38 phosphorylation and MMP13 expression are regulated by Rho/ROCK activation, and support the potential novel pathway that Rho/ROCK is in the upper part of the mechanical stress-induced matrix degeneration cascade in cartilage., [RefSeq, PubMed]; Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CCN2. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion (By similarity)., [UniProtKB]; These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0005518 collagen binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0022617 extracellular matrix disassembly;GO:0030198 extracellular matrix organization;GO:0060349 bone morphogenesis;GO:0030574 collagen catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "O77656-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O77801-1", "uniprot_id": "INSL3_BOVIN", "mass": 14378.0, "length": 132, "protein_name": "Insulin-like 3", "gene_name": "INSL3", "organism": "Bovine", "refseq_name": "insulin-like 3 precursor", "refseq_ac": "NP_776790", "gene_names_uniprotkb": "INSL3; RLF", "gene_names_refseq": "INSL3; RLF", "protein_names_uniprotkb": "Insulin-like 3; Ley-I-L; Leydig insulin-like peptide; Relaxin-like factor", "protein_names_refseq": "insulin-like 3 (Leydig cell); insulin-like 3 precursor; insulin-like peptide-3; ley-I-L; leydig insulin-like peptide; relaxin-like factor", "tax_id": 9913, "disease": "", "pathway": " (bta:281870); (R-BTA-418555); (R-BTA-444821)", "pathway_count": 3, "publication_count": 9, "publication_id_list": "11772026;15956752;21603619;23530236;23546605;26318230;29597124;29984734;8949906", "class_list": "", "function": "BMP6 has a role in downregulating INSL3 and CYP17A1 and other proteins that modulate ovarian androgen production, [RefSeq, PubMed]; INSL3 provides the first example of a gender-specific fetal hormone with the potential to influence both placental and maternal physiology, [RefSeq, PubMed]; Plasma insulin-like peptide 3, testosterone, inhibin, and insulin-like growth factor-I have a relationship with scrotal circumference and testicular weight in Japanese Black beef bull calves, [RefSeq, PubMed]; Relaxin-like factor mRNA was highly expressed in the corpus luteum on days 7 and 14 of pregnancy, [RefSeq, PubMed]; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity)., [UniProtKB]; The likely role of INSL3 as an important intrafollicular modulator of thecal interna cell function/steroidogenesis., [RefSeq, PubMed]; These results suggest that reduced secretions of IGF-I, INSL3, and inhibin surrounding puberty may be associated with semen aberration in beef bulls., [RefSeq, PubMed]; These results suggested an acute regulation of INSL3 by luteinizing hormone (LH) because INSL3 concentrations increased immediately after endogenous and exogenous LH stimulation., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3T065", "ec_number_list": "", "go_molecular_function": "GO:0002020 protease binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0090303 positive regulation of wound healing;GO:0010634 positive regulation of epithelial cell migration", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "O77801-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O97583-1", "uniprot_id": "NDST2_BOVIN", "mass": 100897.0, "length": 884, "protein_name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2", "gene_name": "NDST2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NDST2", "gene_names_refseq": "", "protein_names_uniprotkb": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2; 2.8.2.8; CCL44; Glucosaminyl N-deacetylase/N-sulfotransferase 2; NDST-2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "12658628;9712870", "class_list": "", "function": "Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q862Q7;Q862Y7", "ec_number_list": "2.8.2.8;2.8.2.-;3.-.-.-", "go_molecular_function": "GO:0016787 hydrolase activity;GO:0019213 deacetylase activity;GO:0015016 heparan sulfate N-sulfotransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0030210 heparin proteoglycan biosynthetic process;GO:0015012 heparan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "O97583-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O97711-1", "uniprot_id": "HYAS2_BOVIN", "mass": 63459.0, "length": 552, "protein_name": "Hyaluronan synthase 2", "gene_name": "HAS2", "organism": "Bovine", "refseq_name": "hyaluronan synthase 2", "refseq_ac": "NP_776504", "gene_names_uniprotkb": "HAS2", "gene_names_refseq": "HAS2", "protein_names_uniprotkb": "Hyaluronan synthase 2; 2.4.1.212; HA synthase 2; Hyaluronate synthase 2; Hyaluronic acid synthase 2", "protein_names_refseq": "HA synthase 2; hyaluronan synthase 2; hyaluronate synthase 2; hyaluronic acid synthase 2", "tax_id": 9913, "disease": "", "pathway": " (bta:281220)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "10067958", "class_list": "", "function": "Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation (By similarity). This is one of three isoenzymes responsible for cellular hyaluronan synthesis and it is particularly responsible for the synthesis of high molecular mass hyaluronan (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.212", "go_molecular_function": "GO:0050501 hyaluronan synthase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0036302 atrioventricular canal development;GO:0000271 polysaccharide biosynthetic process;GO:0085029 extracellular matrix assembly;GO:0001570 vasculogenesis;GO:0035810 positive regulation of urine volume", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O97711-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O97817-1", "uniprot_id": "AGRL2_BOVIN", "mass": 165547.0, "length": 1478, "protein_name": "Adhesion G protein-coupled receptor L2", "gene_name": "ADGRL2", "organism": "Bovine", "refseq_name": "adhesion G protein-coupled receptor L2 precursor", "refseq_ac": "NP_851356", "gene_names_uniprotkb": "ADGRL2; LPH2; LPHN2", "gene_names_refseq": "ADGRL2; LEC2; LPHN2", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor L2; CIRL-2; Calcium-independent alpha-latrotoxin receptor 2; Latrophilin-2", "protein_names_refseq": "CIRL-2; adhesion G protein-coupled receptor L2 precursor; calcium-independent alpha-latrotoxin receptor 2; latrophilin-2; lectomedin 2", "tax_id": 9913, "disease": "", "pathway": " (bta:281278)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "10025961", "class_list": "", "function": "Orphan adhesion G protein-coupled receptor (aGPCR), which mediates synapse specificity (By similarity). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors (By similarity). Following G protein-coupled receptor activation, associates with cell adhesion molecules that are expressed at the surface of adjacent cells to direct synapse specificity. Specifically mediates the establishment of perforant-path synapses on CA1-region pyramidal neurons in the hippocampus. Localizes to postsynaptic spines in excitatory synapses in the S.lacunosum-moleculare and interacts with presynaptic cell adhesion molecules, such as teneurins, promoting synapse formation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 9, "predicted_n_glycosites": 9, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "O97805;O97807;O97809;O97810;O97811;O97812;O97813;O97814;O97815;O97816", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:1904861 excitatory synapse assembly;GO:0007165 signal transduction;GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O97817-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00189-1", "uniprot_id": "CP11A_BOVIN", "mass": 60333.0, "length": 520, "protein_name": "Cholesterol side-chain cleavage enzyme, mitochondrial", "gene_name": "CYP11A1", "organism": "Bovine", "refseq_name": "cholesterol side-chain cleavage enzyme, mitochondrial precursor", "refseq_ac": "NP_788817", "gene_names_uniprotkb": "CYP11A1", "gene_names_refseq": "CYP11A1; CYP11A; CYPXIA1; P450(scc); P450scc", "protein_names_uniprotkb": "Cholesterol side-chain cleavage enzyme, mitochondrial; 1.14.15.6; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)", "protein_names_refseq": "cholesterol desmolase; cholesterol side-chain cleavage enzyme, mitochondrial precursor; cholesterol side-chain cleavage enzyme, mitochondrial; cytochrome P450 11A1; cytochrome P450(scc); cytochrome P450, family 11, subfamily A, polypeptide 1", "tax_id": 9913, "disease": "", "pathway": " (bta:338048)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "11412116;1477100;21159775;2154474;22227097;25130438;25746800;28799023;3011431;30641046;3518802;6589615;6654880", "class_list": "", "function": "A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones (PubMed:11412116). Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal (PubMed:11412116). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin) (PubMed:11412116)., [UniProtKB, PubMed]; Bovine CYP11A1 manifests 2beta- and 16beta-hydroxylase activity., [RefSeq, PubMed]; Data indicate a role of cytochrome P450 11A1 (CYP11A1 in sterol metabolism., [RefSeq, PubMed]; Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1., [RefSeq, PubMed]; Isoleucine residues 351 and 461, and leucine residue 355 are important for the cytochrome P450scc functioning towards sterols both with unbranched (cholesterol) and branched (sitosterol) side chains, [RefSeq, PubMed]; We constructed cDNA including genes of the bovine cholesterol hydroxylase/lyase (CHL) system proteins-cytochrome P450scc (CYP11A1), adrenodoxin (Adx) and adrenodoxin reductase (AdR), that are fused into a single ORF using FMDV 2A nucleotide sequences., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q28152", "ec_number_list": "1.14.15.6", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0042359 vitamin D metabolic process;GO:0008203 cholesterol metabolic process;GO:0006700 C21-steroid hormone biosynthetic process;GO:0006704 glucocorticoid biosynthetic process;GO:0071375 cellular response to peptide hormone stimulus", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P00189-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00435-1", "uniprot_id": "GPX1_BOVIN", "mass": 22659.0, "length": 205, "protein_name": "Glutathione peroxidase 1", "gene_name": "GPX1", "organism": "Bovine", "refseq_name": "glutathione peroxidase 1", "refseq_ac": "NP_776501", "gene_names_uniprotkb": "GPX1", "gene_names_refseq": "GPX1", "protein_names_uniprotkb": "Glutathione peroxidase 1; 1.11.1.12; 1.11.1.9; Cellular glutathione peroxidase; GPx-1; GSHPx-1; Phospholipid-hydroperoxide glutathione peroxidase GPX1", "protein_names_refseq": "GPx-1; GSHPx-1; cellular glutathione peroxidase; glutathione peroxidase 1; phospholipid-hydroperoxide glutathione peroxidase GPX1", "tax_id": 9913, "disease": "", "pathway": " (bta:281209); (R-BTA-2142712); (R-BTA-3299685)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "15734734;22089971;24375829;25362850;2976939;6714945;6852035;7873592", "class_list": "", "function": "Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. In platelets catalyzes the reduction of 12-hydroperoxyeicosatetraenoic acid, the primary product of the arachidonate 12-lipoxygenase pathway., [UniProtKB, UniProtKB]; Data indicate a positive correlation between GSH-Px activity and serum selenium concentration for all the cows analysed together., [RefSeq, PubMed]; Did not find any significant inhibition of bovine GPx-1 by (S)- or (R)-misonidazole., [RefSeq, PubMed]; Homocysteine decreases GPx1 activity by altering the translational mechanism, [RefSeq, PubMed]; Studied the importance of selenium in bovine female reproductive function. Gene expression analysis revealed selenoprotein gene GPX1 was significantly up-regulated in large healthy follicles. Erratum:[Metallomics. 2015 Jan;7(1):188. doi: 10.1039/c4mt90049a. PMID: 25427852], [RefSeq, PubMed]; The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance; therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. There is a direct correlation between the concentration of selenium and the activity of this enzyme in lactating cows, with the highest levels observed during the early stage of lactation, suggesting that the generation of reactive oxygen species was higher during this period compared to the late stage. [provided by RefSeq, Jul 2016]., [RefSeq]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 1, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A6QPG3", "ec_number_list": "1.11.1.27;1.16.3.1;1.11.1.9;1.16.3.4;1.11.1.12;1.11.1.-;5.3.3.-;2.5.1.18;4.4.1.20;2.5.1.-;5.3.99.3", "go_molecular_function": "GO:0017124 SH3 domain binding;GO:1990782 protein tyrosine kinase binding;GO:0004602 glutathione peroxidase activity;GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0097413 Lewy body", "go_biological_process": "GO:1902905 positive regulation of supramolecular fiber organization;GO:0060047 heart contraction;GO:0042542 response to hydrogen peroxide;GO:0034599 cellular response to oxidative stress;GO:0010269 response to selenium ion", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P00435-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00669-1", "uniprot_id": "RNS_BOVIN", "mass": 16377.0, "length": 150, "protein_name": "Seminal ribonuclease", "gene_name": "SRN", "organism": "Bovine", "refseq_name": "seminal ribonuclease precursor", "refseq_ac": "NP_861526", "gene_names_uniprotkb": "SRN", "gene_names_refseq": "LOC280930; RAC1; RNASE1; SRN", "protein_names_uniprotkb": "Seminal ribonuclease; 4.6.1.18; Ribonuclease BS-1; S-RNase; Seminal RNase", "protein_names_refseq": "S-RNase; ribonuclease A C1; ribonuclease BS-1; seminal RNase; seminal ribonuclease precursor; seminal ribonuclease", "tax_id": 9913, "disease": "", "pathway": " (bta:280930)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10082366;15299514;2057997;23071641;2315023;24140346;24616921;26573727;3840434;4664228;4761089;534646;6673761;6846794;7317378;7731986;8587129", "class_list": "", "function": "A report of the first clear experimental evidence on the formation of a C-terminal swapped dimer of the monomeric BS-RNase derivatives., [RefSeq, PubMed]; Data indicate that BS-RNase oligomers are more enzymatically active than the native dimer., [RefSeq, PubMed]; Data suggest that dimerization of seminal ribonuclease (SRN) facilitates three-dimensional domain swapping; both swapped and un-swapped dimers of SRN exhibit increased flexibility as compared to monomeric subunit SRN., [RefSeq, PubMed]; In the regions involved in 3D swapping, the study observed an accumulation of weaknesses in the monomer, which disappear in the dimer and especially in the swapped dimer., [RefSeq, PubMed]; This enzyme hydrolyzes both single- and double-stranded RNA., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016787 hydrolase activity;GO:0042802 identical protein binding;GO:0003676 nucleic acid binding;GO:0004540 RNA nuclease activity;GO:0004522 ribonuclease A activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0050830 defense response to Gram-positive bacterium", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P00669-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00974-1", "uniprot_id": "BPT1_BOVIN", "mass": 10903.0, "length": 100, "protein_name": "Pancreatic trypsin inhibitor", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Pancreatic trypsin inhibitor; Aprotinin; BPI; BPTI; Basic protease inhibitor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "1383552;1714504;2322242;2420326;2441071;2456884;5296424;5447861;5860161;6053284;6580617", "class_list": "", "function": "Inhibits trypsin, kallikrein, chymotrypsin, and plasmin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019870 potassium channel inhibitor activity;GO:0002020 protease binding;GO:0004867 serine-type endopeptidase inhibitor activity;GO:0005509 calcium ion binding;GO:0043199 sulfate binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0097180 serine protease inhibitor complex", "go_biological_process": "GO:0090331 negative regulation of platelet aggregation;GO:0070495 negative regulation of thrombin-activated receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P00974-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00978-1", "uniprot_id": "AMBP_BOVIN", "mass": 39235.0, "length": 352, "protein_name": "Protein AMBP", "gene_name": "AMBP", "organism": "Bovine", "refseq_name": "protein AMBP precursor", "refseq_ac": "NP_776414", "gene_names_uniprotkb": "AMBP; ITIL", "gene_names_refseq": "AMBP", "protein_names_uniprotkb": "Protein AMBP; BI-14; Bikunin; Cumulus extracellular matrix-stabilizing factor; ESF; HI-30", "protein_names_refseq": "inter-alpha-trypsin inhibitor (protein HC), light; protein AMBP precursor; protein AMBP", "tax_id": 9913, "disease": "", "pathway": " (bta:280996)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "1376324;2408637;6199275;6199276;8611630", "class_list": "", "function": "Antioxidant and tissue repair protein with reductase, heme-binding and radical-scavenging activities. Removes and protects against harmful oxidants and repairs macromolecules in intravascular and extravascular spaces and in intracellular compartments. Intravascularly, plays a regulatory role in red cell homeostasis by preventing heme- and reactive oxygen species-induced cell damage. Binds and degrades free heme to protect fetal and adult red blood cells from hemolysis. Reduces extracellular methemoglobin, a Fe3+ (ferric) form of hemoglobin that cannot bind oxygen, back to the Fe2+ (ferrous) form deoxyhemoglobin, which has oxygen-carrying potential. Upon acute inflammation, inhibits oxidation of low-density lipoprotein particles by MPO and limits vascular damage. Extravascularly, protects from oxidation products formed on extracellular matrix structures and cell membranes. Catalyzes the reduction of carbonyl groups on oxidized collagen fibers and preserves cellular and extracellular matrix ultrastructures. Importantly, counteracts the oxidative damage at blood-placenta interface, preventing leakage of free fetal hemoglobin into the maternal circulation. Intracellularly, has a role in maintaining mitochondrial redox homeostasis. Bound to complex I of the respiratory chain of mitochondria, may scavenge free radicals and preserve mitochondrial ATP synthesis. Protects renal tubule epithelial cells from heme-induced oxidative damage to mitochondria. Reduces cytochrome c from Fe3+ (ferric) to the Fe2+ (ferrous) state through formation of superoxide anion radicals in the presence of ascorbate or NADH/NADPH electron donor cofactors, ascorbate being the preferred cofactor (By similarity). Has a chaperone role in facilitating the correct folding of bikunin in the endoplasmic reticulum compartment (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Kunitz-type serine protease inhibitor and structural component of extracellular matrix with a role in extracellular space remodeling and cell adhesion. Among others, has antiprotease activity toward kallikrein, a protease involved in airway inflammation; inhibits GZMK/granzyme, a granule-stored serine protease involved in NK and T cell cytotoxic responses; and inhibits PLG/plasmin, a protease required for activation of matrix metalloproteinases. As part of I-alpha-I complex, provides for the heavy chains to be transferred from I-alpha-I complex to hyaluronan in the presence of TNFAIP6, in a dynamic process that releases free bikunin and remodels extracellular matrix proteoglycan structures. Free bikunin, but not its heavy chain-bound form, acts as a potent protease inhibitor in airway secretions (By similarity). Part of hyaluronan-rich extracellular matrix that surrounds oocyte during cumulus oophorus expansion, an indispensable process for proper ovulation (By similarity). Also inhibits calcium oxalate crystallization (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Kunitz-type serine protease inhibitor. Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation. Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "P35420;Q28020;Q3SZZ4", "ec_number_list": "", "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity;GO:0042803 protein homodimerization activity;GO:0016491 oxidoreductase activity;GO:0020037 heme binding;GO:0019862 IgA binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005743 mitochondrial inner membrane;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P00978-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01044-1", "uniprot_id": "KNG1_BOVIN", "mass": 68890.0, "length": 621, "protein_name": "Kininogen-1", "gene_name": "KNG1", "organism": "Bovine", "refseq_name": "kininogen-1 isoform I precursor", "refseq_ac": "NP_786968", "gene_names_uniprotkb": "KNG1", "gene_names_refseq": "KNG1; KNG2; KNG", "protein_names_uniprotkb": "Kininogen-1; Kallidin II; Kallidin I; Kininogen I; Thiol proteinase inhibitor", "protein_names_refseq": "bradykinin; kininogen II; kininogen I; kininogen-1 isoform I precursor; kininogen-2; thiol proteinase inhibitor", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 8, "publication_id_list": "1169237;12181294;18191860;19674964;3546295;4986212;6571699;6572010", "class_list": "", "function": "Bradykini stimulates endothelial cell fatty acid oxidation by calmodulin-dependent kinase kinase -dependent activation of AMP-activated protein kinase (AMPK), [RefSeq, PubMed]; Bradykinin, together with its precursor and tissue kallikrein, is continuously released into the vasculature of the isolated, perfused, lactating bovine udder., [RefSeq, PubMed]; Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. LMW-kininogen inhibits the aggregation of thrombocytes. LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting., [UniProtKB]; The active peptide bradykinin is a potent vasodilatator that is released from HMW-kininogen shows a variety of physiological effects: (A) influence in smooth muscle contraction, (B) induction of hypotension, (C) natriuresis and diuresis, (D) decrease in blood glucose level, (E) it is a mediator of inflammation and causes (E1) increase in vascular permeability, (E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action)., [UniProtKB, UniProtKB]", "predicted_glycosites": 12, "predicted_n_glycosites": 1, "predicted_o_glycosites": 11, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 5, "reported_o_glycosites": 2, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 5, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 5, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 9015, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 19, "binding_glycan_count": 0, "secondary_ac_list": "P01046;Q2KJ62", "ec_number_list": "", "go_molecular_function": "GO:0004869 cysteine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006954 inflammatory response;GO:0007162 negative regulation of cell adhesion;GO:0007596 blood coagulation;GO:0042311 vasodilation;GO:0030195 negative regulation of blood coagulation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P01044-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01223-1", "uniprot_id": "TSHB_BOVIN", "mass": 15624.0, "length": 138, "protein_name": "Thyrotropin subunit beta", "gene_name": "TSHB", "organism": "Bovine", "refseq_name": "thyrotropin subunit beta precursor", "refseq_ac": "NP_776630", "gene_names_uniprotkb": "TSHB", "gene_names_refseq": "TSHB", "protein_names_uniprotkb": "Thyrotropin subunit beta; TSH-B; TSH-beta; Thyroid-stimulating hormone subunit beta; Thyrotropin beta chain", "protein_names_refseq": "TSH-B; TSH-beta; thyroid stimulating hormone beta subunit; thyroid stimulating hormone beta; thyroid stimulating hormone, beta polypeptide; thyrotropin beta chain; thyrotropin beta subunit; thyrotropin subunit beta precursor; thyrotropin subunit beta", "tax_id": 9913, "disease": "", "pathway": " (bta:281552); (R-BTA-209822); (R-BTA-209968); (R-BTA-375281); (R-BTA-418555)", "pathway_count": 5, "publication_count": 8, "publication_id_list": "10078873;11520036;18074395;26610751;5101173;5101174;6325416;8670056", "class_list": "", "function": "Identification for the first time that ADAM10 is a TSHR cleavage enzyme and demonstration that TSH regulates its activation, [RefSeq, PubMed]; Indispensable for the control of thyroid structure and metabolism., [UniProtKB]; Nitric oxide decreases TSH-induced FoxE1 expression, thus repressing the transcripcional activation of TPO gene., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 1, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 207, "biomarker_type": "", "glycan_count": 70, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 8.0, "record_id": "P01223-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01246-1", "uniprot_id": "SOMA_BOVIN", "mass": 24558.0, "length": 217, "protein_name": "Somatotropin", "gene_name": "GH1", "organism": "Bovine", "refseq_name": "somatotropin precursor", "refseq_ac": "NP_851339", "gene_names_uniprotkb": "GH1; GH", "gene_names_refseq": "GH1; GH", "protein_names_uniprotkb": "Somatotropin; Growth hormone", "protein_names_refseq": "somatotropin precursor; somatotropin", "tax_id": 9913, "disease": "", "pathway": " (biu:109574543); (bta:280804)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "1123321;2021631;30011805;31697176;32259636;32591394;38739483;3899556;4580883;4584625;4856718;5579941;6296767;6303731;6357899;6893197", "class_list": "", "function": "Exposure to growth hormone is associated with hepatic up-regulation of cPLA2alpha and COX., [RefSeq, PubMed]; Growth Hormone Reprograms Macrophages toward an Anti-Inflammatory and Reparative Profile in an MAFB-Dependent Manner., [RefSeq, PubMed]; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues., [UniProtKB]; The effect of miR-23b-3p on regulating GH by targeting POU1F1 in Yanbian yellow cattle., [RefSeq, PubMed]; The effect of miR-93 on GH secretion in pituitary cells of Yanbian yellow cattle., [RefSeq, PubMed]; Tracing Recombinant Bovine Somatotropin Ab(Use) Through Gene Expression in Blood, Hair Follicles, and Milk Somatic Cells. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4GX96;Q28117;Q3LS73", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0005179 hormone activity;GO:0008083 growth factor activity;GO:0005131 growth hormone receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:2000767 positive regulation of cytoplasmic translation;GO:1903576 response to L-arginine;GO:0008283 cell population proliferation;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P01246-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01267-1", "uniprot_id": "THYG_BOVIN", "mass": 303222.0, "length": 2769, "protein_name": "Thyroglobulin", "gene_name": "TG", "organism": "Bovine", "refseq_name": "thyroglobulin precursor", "refseq_ac": "NP_776308", "gene_names_uniprotkb": "TG", "gene_names_refseq": "TG", "protein_names_uniprotkb": "Thyroglobulin; Tg", "protein_names_refseq": "hereditary goitre; thyroglobulin precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:280706)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "26125728;27065254;27676653;28701697;29440273;3032624;34726172;3681978;3855243;3855750;4335100;8424663", "class_list": "", "function": "Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) (By similarity). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling (By similarity). Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream (By similarity). One dimer produces 7 thyroid hormone molecules (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Antepenultimate residue of TG as a major T3-forming site, but also demonstrate that the side chain of this residue intimately interacts with the same residue in the apposed monomer of the TG dimer., [RefSeq, PubMed]; Data suggest that flotillin-1 and flotillin-2 function as thyroglobulin-binding proteins in lipid rafts of thyrocytes; these interactions appear to exert negative-feedback effects on gene expression in thyrocytes., [RefSeq, PubMed]; The results of this study suggest that TG gene-specific SNPs may be a useful marker for growth traits in marker-assisted selection programs in beef cattle. Publication Status: Online-Only, [RefSeq, PubMed]; The structure of natively iodinated bovine thyroglobulin., [RefSeq, PubMed]; There were no associations between x genotype and fertility related traits in this study., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 14, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 1, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 15, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 15, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 9015, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 14, "binding_glycan_count": 0, "secondary_ac_list": "O18976;Q28196;Q95478", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity;GO:0042393 histone binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0042446 hormone biosynthetic process;GO:0006590 thyroid hormone generation", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "P01267-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01268-1", "uniprot_id": "PTHY_BOVIN", "mass": 12980.0, "length": 115, "protein_name": "Parathyroid hormone", "gene_name": "PTH", "organism": "Bovine", "refseq_name": "parathyroid hormone precursor", "refseq_ac": "NP_776379", "gene_names_uniprotkb": "PTH", "gene_names_refseq": "PTH", "protein_names_uniprotkb": "Parathyroid hormone; PTH; Parathyrin", "protein_names_refseq": "parathyrin; parathyroid hormone precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:280903); (R-BTA-373080); (R-BTA-418555)", "pathway_count": 3, "publication_count": 14, "publication_id_list": "10623601;19957341;21076856;21611963;23639875;26851123;388425;4322265;4522780;5275384;5531031;6086460;6170060;6185374", "class_list": "", "function": "Osteoblast 2-deoxyglucose uptake and glycogen synthesis were increased after exposure to low concentrations (0.1 nmol/l and above) of PTH., [RefSeq, PubMed]; Parathyroid hormone elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells., [UniProtKB, UniProtKB]; Parathyroid hormone stimulated growth and decreased Col-X deposition via phosphotidylinositol-3,4,5 triphosphate kinase and mitogen activating protein kinase pathways in avian sterna., [RefSeq, PubMed]; These data highlight the ability of PTH to phosphorylate beta-catenin directly via PKA., [RefSeq, PubMed]; These data suggest that prostaglandin E2 acting via EP4R on bone marrow macrophages committed to the osteoblast cell lineage, stimulated secretion of a factor or factors that acted to suppress PTH-stimulated osteoblast differentiation., [RefSeq, PubMed]; These results suggest that in vivo PTH treatment increased in vitro osteoclastogenesis and resorption without altering the number of osteoclast precursors., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity;GO:0051428 peptide hormone receptor binding;GO:0031857 type 1 parathyroid hormone receptor binding;GO:0031856 parathyroid hormone receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007267 cell-cell signaling;GO:0010629 negative regulation of gene expression;GO:0006874 intracellular calcium ion homeostasis;GO:0030501 positive regulation of bone mineralization;GO:0045725 positive regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P01268-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01272-1", "uniprot_id": "GLUC_BOVIN", "mass": 20944.0, "length": 180, "protein_name": "Pro-glucagon", "gene_name": "GCG", "organism": "Bovine", "refseq_name": "pro-glucagon precursor", "refseq_ac": "NP_776341", "gene_names_uniprotkb": "GCG", "gene_names_refseq": "GCG; GLP-1; GLP-2", "protein_names_uniprotkb": "Pro-glucagon", "protein_names_refseq": "pro-glucagon precursor; pro-glucagon", "tax_id": 9913, "disease": "", "pathway": " (bta:280802); (R-BTA-163359); (R-BTA-381676); (R-BTA-381771); (R-BTA-416476); (R-BTA-418555); (R-BTA-420092); (R-BTA-422085)", "pathway_count": 8, "publication_count": 9, "publication_id_list": "10322410;10605628;12554744;12626323;20688461;30660418;5102927;6577439;6631957", "class_list": "", "function": "Data demonstrate that cattle express proglucagon and glucagon-like peptide 2 receptor mRNA primarily in small intestinal and colon tissues and increased nutrient intake increases ileal proglucagon mRNA and plasma glucagon-like peptide 2, [RefSeq, PubMed]; May modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life., [UniProtKB, UniProtKB]; Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. Binds to and activates the glucagon receptor GCGR, which couples to the G(s) G protein and elevates intracellular cAMP, triggering downstream metabolic responses., [UniProtKB, UniProtKB]; Potent stimulator of glucose-dependent insulin release. Also stimulates insulin release in response to IL6. Plays important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Has growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion. Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation. Inhibits beta cell apoptosis., [UniProtKB, UniProtKB]; Significantly reduces food intake. Inhibits gastric emptying in humans. Suppression of gastric emptying may lead to increased gastric distension, which may contribute to satiety by causing a sensation of fullness., [UniProtKB, UniProtKB]; Stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability., [UniProtKB, UniProtKB]; These findings suggest that pulse-dosing of butyrate slightly increased both GLP-1 and GLP-2 concentrations at specific time points and this might be promoted by direct or indirect effect of butyrate on the intestinal L-cells.[GLP 1, GLP 2], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3T0X0", "ec_number_list": "", "go_molecular_function": "GO:0031769 glucagon receptor binding;GO:0042802 identical protein binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0008610 lipid biosynthetic process;GO:0043066 negative regulation of apoptotic process;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0071377 cellular response to glucagon stimulus", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P01272-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01966-1", "uniprot_id": "HBA_BOVIN", "mass": 15184.0, "length": 142, "protein_name": "Hemoglobin subunit alpha", "gene_name": "HBA", "organism": "Bovine", "refseq_name": "hemoglobin subunit alpha", "refseq_ac": "NP_001070890", "gene_names_uniprotkb": "HBA", "gene_names_refseq": "HBA2; HBA; alpha globin", "protein_names_uniprotkb": "Hemoglobin subunit alpha; Alpha-globin; Hemoglobin alpha chain", "protein_names_refseq": "alpha-globin; hemoglobin alpha chain; hemoglobin subunit alpha", "tax_id": 9913, "disease": "", "pathway": " (bta:100140149); (bta:512439); (R-BTA-1237044); (R-BTA-1247673); (R-BTA-2168880); (R-BTA-9707564); (R-BTA-9707616)", "pathway_count": 7, "publication_count": 14, "publication_id_list": "11369847;21209280;22952902;23991043;2769252;28608588;29197256;30573663;30864762;34019948;6048714;7500030;8315383;8411160", "class_list": "", "function": "A broad spectrum of alpha-thalassemia alleles has been detected among Iranians and -alpha3.7 kb was the most prevalent Thalassemia mutation., [RefSeq, PubMed]; Both Ciprofloxacin and enrofloxacin could lead to the conformational and microenvironmental changes of bovine hemoglobin., [RefSeq, PubMed]; Data indicate that on incubating hemoglobin with glyoxal for 0-20 days, advanced glycation end products (AGEs) were detected on day 20. Publication Status: Online-Only, [RefSeq, PubMed]; Determination of a representative formal redox potentials of the Fe(II)/Fe(III) redox couple cyanhaemoglobin/cyanmethaemoglobin and the myoglobin/metmyoglobin , at pH=7 and related to the state in solution, was the objective of this work., [RefSeq, PubMed]; Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling., [UniProtKB, UniProtKB]; Involved in oxygen transport from the lung to the various peripheral tissues., [UniProtKB]; Ultraviolet irradiation results in fluorescence enhancement of bovine hemoblobin in a dose-dependent manner., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A3KN13;Q3SZE0;Q9TTR9;Q9TTS0;Q9TTS1", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0019825 oxygen binding;GO:0005344 oxygen carrier activity", "go_cellular_component": "GO:0005833 hemoglobin complex;GO:0031838 haptoglobin-hemoglobin complex", "go_biological_process": "GO:0048821 erythrocyte development;GO:0015671 oxygen transport", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P01966-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P02192-1", "uniprot_id": "MYG_BOVIN", "mass": 17078.0, "length": 154, "protein_name": "Myoglobin", "gene_name": "MB", "organism": "Bovine", "refseq_name": "myoglobin", "refseq_ac": "NP_776306", "gene_names_uniprotkb": "MB", "gene_names_refseq": "GLNG; MB", "protein_names_uniprotkb": "Myoglobin; 1.11.1.-; 1.7.-.-; Nitrite reductase MB; Pseudoperoxidase MB", "protein_names_refseq": "globin G; myoglobin; nitrite reductase MB; pseudoperoxidase MB", "tax_id": 9913, "disease": "", "pathway": " (bta:280695); (R-BTA-8981607)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "20374756;22681513;2659586;26946475;28974698;5477290", "class_list": "", "function": "Glycine at E14 in myoglobin enhances autoxidation and hemin loss rates., [RefSeq, PubMed]; Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand. Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide. Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity., [UniProtKB, UniProtKB]; MyoG drives SIX1 transcription indirectly via the MEF3 motif. Taken together these interactions suggest a key functional role for SIX1 in mediating skeletal muscle growth in cattle Publication Status: Online-Only, [RefSeq, PubMed]; These results suggest an important role of genetics in meat color variation for cattle raised under the tropic conditions., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3ZC11", "ec_number_list": "1.15.1.1;1.11.1.-;1.7.-.-", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0019825 oxygen binding;GO:0004601 peroxidase activity;GO:0005344 oxygen carrier activity", "go_cellular_component": "GO:0016528 sarcoplasm", "go_biological_process": "GO:0003009 skeletal muscle contraction;GO:0019430 removal of superoxide radicals;GO:0015671 oxygen transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P02192-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P02676-1", "uniprot_id": "FIBB_BOVIN", "mass": 53340.0, "length": 468, "protein_name": "Fibrinogen beta chain", "gene_name": "FGB", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FGB", "gene_names_refseq": "", "protein_names_uniprotkb": "Fibrinogen beta chain", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "11593005;1942070;19674964;434821;6262803", "class_list": "", "function": "Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 1, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix;GO:0005577 fibrinogen complex", "go_biological_process": "GO:0045087 innate immune response;GO:0007160 cell-matrix adhesion;GO:0002250 adaptive immune response;GO:0070527 platelet aggregation;GO:0051258 protein polymerization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P02676-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P02702-1", "uniprot_id": "FOLR1_BOVIN", "mass": 27922.0, "length": 241, "protein_name": "Folate receptor alpha", "gene_name": "FOLR1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FOLR1", "gene_names_refseq": "", "protein_names_uniprotkb": "Folate receptor alpha; FBP; FR-alpha; Folate receptor 1; Folate-binding protein 1; Milk folate-binding protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:516067)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release (By similarity). Required for normal embryonic development and normal cell proliferation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005542 folic acid binding;GO:0061714 folic acid receptor activity;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005768 endosome;GO:0016323 basolateral plasma membrane;GO:0009897 external side of plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0035036 sperm-egg recognition;GO:0007155 cell adhesion;GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization;GO:0015884 folic acid transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P02702-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P02754-1", "uniprot_id": "LACB_BOVIN", "mass": 19883.0, "length": 178, "protein_name": "Beta-lactoglobulin", "gene_name": "LGB", "organism": "Bovine", "refseq_name": "beta-lactoglobulin precursor", "refseq_ac": "NP_776354", "gene_names_uniprotkb": "LGB", "gene_names_refseq": "BLG; LGB; PAEP", "protein_names_uniprotkb": "Beta-lactoglobulin; Beta-LG", "protein_names_refseq": "bLG C; beta lactoglobulin C; beta lactoglobulin D; beta-LG; beta-lactoglobulin precursor; beta-lactoglobulin; lactoglobulin, beta", "tax_id": 9913, "disease": "", "pathway": " (bta:280838)", "pathway_count": 1, "publication_count": 37, "publication_id_list": "10457108;10595563;10640911;11342718;11729348;12133623;12170271;16220005;1623143;1720415;17991420;18331418;2340107;2349102;23964685;24658798;2477067;26174000;2701948;27456117;27957499;3202951;34019948;3443305;36307246;37604312;4569282;4611888;4737332;511095;6897774;7693669;8601463;9115437;9313138;9671121;9760236", "class_list": "", "function": "Data (including data from molecular dynamic simulations) suggest that -OH groups of 3-hydroxypalmitic acid and 16-hydroxypalmitic acid act as hydrogen-bond donors in a hydrophobic protein cavity of beta-lactoglobulin. [BLG, beta-lactoglobulin], [RefSeq, PubMed]; LG plays a key role in enhancing immune responses by promoting cell proliferation through IgM receptor., [RefSeq, PubMed]; Primary component of whey, it binds retinol and is probably involved in the transport of that molecule., [UniProtKB]; The conformational complexity of BLG protein-protein self-association and palmitic acid (PLM) or dodecyl sulfate (SDS) ligand recognition in the monomeric and dimeric state, was investigated., [RefSeq, PubMed]; The effect of beta-lactoglobulin (beta-LG) phenotype on the fatty acid composition and antioxidant capacity of milk is variable, which could partly be the result of a beta-LG phenotype x diet interaction., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 1, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 2, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 8, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q32P89", "ec_number_list": "", "go_molecular_function": "GO:0036041 long-chain fatty acid binding;GO:0042802 identical protein binding;GO:0019841 retinol binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 4.8, "record_id": "P02754-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P02777-1", "uniprot_id": "PLF4_BOVIN", "mass": 9523.0, "length": 88, "protein_name": "Platelet factor 4", "gene_name": "PF4", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PF4; CXCL4; SCYB4", "gene_names_refseq": "", "protein_names_uniprotkb": "Platelet factor 4; C-X-C motif chemokine 4; PF-4", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "1409574;2065087;2914894;3767377", "class_list": "", "function": "Chemokine released during platelet aggregation that plays a role in different biological processes including hematopoiesis, cell proliferation, differentiation, and activation. Acts via different functional receptors including CCR1, CXCR3A or CXCR3B. Upon interaction with CXCR3A receptor, induces activated T-lymphocytes migration mediated via downstream Ras/extracellular signal-regulated kinase (ERK) signaling. Neutralizes the anticoagulant effect of heparin by binding more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Plays a role in the inhibition of hematopoiesis and in the maintenance of hematopoietic stem cell (HSC) quiescence. Chemotactic for neutrophils and monocytes via CCR1. Inhibits endothelial cell proliferation. In cooperation with toll-like receptor 8/TLR8, induces chromatin remodeling and activates inflammatory gene expression via the TBK1-IRF5 axis. In addition, induces myofibroblast differentiation and collagen synthesis in different precursor cells, including endothelial cells, by stimulating endothelial-to-mesenchymal transition. Interacts with thrombomodulin/THBD to enhance the activation of protein C and thus potentiates its anticoagulant activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 1, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0008009 chemokine activity;GO:0045236 CXCR chemokine receptor binding;GO:0048248 CXCR3 chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006954 inflammatory response;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0042127 regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P02777-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P02784-1", "uniprot_id": "SFP1_BOVIN", "mass": 15481.0, "length": 134, "protein_name": "Seminal plasma protein PDC-109", "gene_name": "", "organism": "Bovine", "refseq_name": "seminal plasma protein PDC-109 precursor", "refseq_ac": "NP_001001145", "gene_names_uniprotkb": "", "gene_names_refseq": "BSP1; PDC-109; PDC109; SVSP109", "protein_names_uniprotkb": "Seminal plasma protein PDC-109; BSP-A1 and BSP-A2; SVSP109; Seminal vesicle secretory protein 109", "protein_names_refseq": "BSP-A1 and BSP-A2; seminal plasma protein PDC-109 precursor; seminal plasma protein PDC-109; seminal vesicle secretory protein 109", "tax_id": 9913, "disease": "", "pathway": " (bta:407187)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "1731074;1932121;1993183;26484773;27118515;28965950;30765224;31552690;3229283;6870895;8070564;8654577", "class_list": "", "function": "Abundant in bull sperm, more in low fertility group than in high fertility group, [RefSeq, PubMed]; Conserved core tryptophans of FnII domains are crucial for the membranolytic and chaperone-like activities of bovine seminal plasma protein PDC-109., [RefSeq, PubMed]; Could enhance the fertilizing capacity of bull spermatozoa upon interaction with heparin-like glycosaminoglycans present in the female genital tract. Exhibits both simulatory and inhibitory actions on the release of pituitary gonadotropins., [UniProtKB]; Glycosylation decreases the membranolytic activity of PDC-109 but increases its chaperone-like activities., [RefSeq, PubMed]; PDC-109 binds to choline phospholipids of the sperm plasma membrane and induces an efflux of cholesterol and choline phospholipids, which is crucial for sperm capacitation. PDC-109 also exhibits chaperone-like activity and protects target proteins against various kinds of stress. Spermine and spermidine, present in high concentration in the seminal plasma, increase the ability of PDC-109 to perturb membrane structure., [RefSeq, PubMed]; This is the first report showing that more than two forms of BSP1 are found in the seminal plasma of Nelore adult bulls and not all animals have a similar abundance of each BSP1 form., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 1, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 2, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 3, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface", "go_biological_process": "GO:0033700 phospholipid efflux;GO:0007338 single fertilization;GO:0048240 sperm capacitation;GO:1902492 positive regulation of sperm capacitation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P02784-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P62998-1", "uniprot_id": "RAC1_BOVIN", "mass": 21450.0, "length": 192, "protein_name": "Ras-related C3 botulinum toxin substrate 1", "gene_name": "RAC1", "organism": "Bovine", "refseq_name": "ras-related C3 botulinum toxin substrate 1", "refseq_ac": "NP_776588", "gene_names_uniprotkb": "RAC1", "gene_names_refseq": "RAC1", "protein_names_uniprotkb": "Ras-related C3 botulinum toxin substrate 1; 3.6.5.2; p21-Rac1", "protein_names_refseq": "p21-Rac1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 1; rho family, small GTP binding protein Rac1", "tax_id": 9913, "disease": "", "pathway": " (bta:281440)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10802295;12754309;16339142;16723384;22773836;25677088;25924612;9417078", "class_list": "", "function": "A critical role for H(2)O(2) in angiotensin-II signaling to the endothelial cytoskeleton in a novel pathway that is critically dependent on MARCKS, Rac1, and c-Abl., [RefSeq, PubMed]; G protein betagamma subunits, Src kinase and the GEF Tiam1 are upstream modulators of S1P-mediated Rac1 activation, and Rac1 has a role in S1P-mediated activation of PI 3-kinase/Akt/endothelial nitric-oxide synthase signaling in vascular endothelial cells, [RefSeq, PubMed]; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Stimulates PKN2 kinase activity. In concert with RAB7A, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts. In podocytes, promotes nuclear shuttling of NR3C2; this modulation is required for a proper kidney functioning. Required for atypical chemokine receptor ACKR2-induced LIMK1-PAK1-dependent phosphorylation of cofilin (CFL1) and for up-regulation of ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (By similarity). In neurons, is involved in dendritic spine formation and synaptic plasticity (By similarity). In hippocampal neurons, involved in spine morphogenesis and synapse formation, through local activation at synapses by guanine nucleotide exchange factors (GEFs), such as ARHGEF6/ARHGEF7/PIX (By similarity). In synapses, seems to mediate the regulation of F-actin cluster formation performed by SHANK3 (By similarity). In neurons, plays a crucial role in regulating GABA(A) receptor synaptic stability and hence GABAergic inhibitory synaptic transmission through its role in PAK1 activation and eventually F-actin stabilization (By similarity). Required for DSG3 translocation to cell-cell junctions, DSG3-mediated organization of cortical F-actin bundles and anchoring of actin at cell junctions; via interaction with DSG3 (By similarity). Subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)) (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Rac1 modification by electrophiles such as 15-deoxy-delta(12,14)-prostaglandin J2 may alter redox signaling and vascular endothelial cells function., [RefSeq, PubMed]; Rac1 only partially restores the spreading defects of integrin linked kinasse (ILK)-depleted cells, suggesting that an additional ILK-dependent signal is required for cell spreading., [RefSeq, PubMed]; Rac1 was activated by secretory stimuli and modulated the secretory pathway downstream of Ca2+ influx, partly through regulation of cytoskeletal organization, [RefSeq, PubMed]; Sig1R through Rac1 signaling induces mild oxidative stress that possibly is involved in the regulation of neuroplasticity Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O95501;P15154;Q3ZBW9;Q9BTB4", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding;GO:0051022 Rho GDP-dissociation inhibitor binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0001934 positive regulation of protein phosphorylation;GO:0007015 actin filament organization;GO:0032956 regulation of actin cytoskeleton organization;GO:0071526 semaphorin-plexin signaling pathway;GO:0001764 neuron migration", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P62998-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q27975-1", "uniprot_id": "HS71A_BOVIN", "mass": 70259.0, "length": 641, "protein_name": "Heat shock 70 kDa protein 1A", "gene_name": "HSPA1A", "organism": "Bovine", "refseq_name": "heat shock 70 kDa protein 1B", "refseq_ac": "NP_976067", "gene_names_uniprotkb": "HSPA1A; HSP70-1", "gene_names_refseq": "HSP70-1; HSP70-2; HSP70; HSPA1A; HSPA1B; HSPA1; HSPA2", "protein_names_uniprotkb": "Heat shock 70 kDa protein 1A; HSP70.1; Heat shock 70 kDa protein 1", "protein_names_refseq": "70 kda heat shock protein-2; HSP70.1; HSP70.2; Heat Shock Protein 70; chaperone; heat shock 70 kD protein 1; heat shock 70 kD protein 2; heat shock 70 kDa protein 1A; heat shock 70 kDa protein 1B; heat shock 70 kDa protein 2; heat shock 70kDa protein 1A; heat shock 70kDa protein 1B; heat-shock 70-kilodalton protein 1A; heat-shock 70-kilodalton protein 1B", "tax_id": 9913, "disease": "", "pathway": " (bta:282254); (R-BTA-3371453); (R-BTA-3371497); (R-BTA-3371568); (R-BTA-3371571); (R-BTA-450408); (R-BTA-6798695); (R-BTA-9833482); (R-BTA-9841251)", "pathway_count": 9, "publication_count": 9, "publication_id_list": "12755819;15491140;25592821;26066050;27264883;30196903;30838506;7826329;7943958", "class_list": "", "function": "Hsp70 gene is a promising candidate gene to be validated in independent cattle populations and functional studies related to cold stress resilience in cattle., [RefSeq, PubMed]; In Sahiwal cattle the mRNA expression of HSP70 and its protein concentration were higher (P<0.05) during peak summer (44 degrees C) and winter (10 degrees C) as compared to Frieswal cattle. This investigation supports the earlier information on the higher adaptability of indigenous cattle breeds to hot and humid conditions compared to the crossbreds of temperate cattle breeds., [RefSeq, PubMed]; In vitro acute heat stress and Geranylgeranylacetone induction increased the level of Hsp70 which upregulated the expression of TLR2/4 and NOD1/2 in both the cell cultured models. However, the expression level of TLR4 was found to be highest followed by NOD2, TLR2 and NOD1., [RefSeq, PubMed]; Inhibition of Hsp70 by using the Hsp70 inhibitor KNK437 or knock down Hsp70 using siRNA exaggerated and overexpression of Hsp70 prevented the second phase disruption of lung endothelial integrity. Publication Status: Online-Only, [RefSeq, PubMed]; It is suggested that 9 SNPs increase the susceptibility to mastitis due to their low polymorphisms and can be used as molecular markers to breed the dairy cows resistant to mastitis., [RefSeq, PubMed]; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The co-chaperones have been shown to not only regulate different steps of the ATPase cycle, but they also have an individual specificity such that one co-chaperone may promote folding of a substrate while another may promote degradation. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release. The co-chaperones are of three types: J-domain co-chaperones such as HSP40s (stimulate ATPase hydrolysis by HSP70), the nucleotide exchange factors (NEF) such as BAG1/2/3 (facilitate conversion of HSP70 from the ADP-bound to the ATP-bound state thereby promoting substrate release), and the TPR domain chaperones such as HOPX and STUB1. Maintains protein homeostasis during cellular stress through two opposing mechanisms: protein refolding and degradation. Its acetylation/deacetylation state determines whether it functions in protein refolding or protein degradation by controlling the competitive binding of co-chaperones HOPX and STUB1. During the early stress response, the acetylated form binds to HOPX which assists in chaperone-mediated protein refolding, thereafter, it is deacetylated and binds to ubiquitin ligase STUB1 that promotes ubiquitin-mediated protein degradation. Regulates centrosome integrity during mitosis, and is required for the maintenance of a functional mitotic centrosome that supports the assembly of a bipolar mitotic spindle. Enhances STUB1-mediated SMAD3 ubiquitination and degradation and facilitates STUB1-mediated inhibition of TGF-beta signaling. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation. Required as a co-chaperone for optimal STUB1/CHIP ubiquitination of NFATC3 (By similarity). Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q27964;Q6DLW1;Q7YQF7", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0003714 transcription corepressor activity;GO:0016887 ATP hydrolysis activity;GO:0031072 heat shock protein binding;GO:0097718 disordered domain specific binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0007041 lysosomal transport;GO:0042026 protein refolding;GO:1901673 regulation of mitotic spindle assembly", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q27975-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2T9T3-1", "uniprot_id": "RPAB1_BOVIN", "mass": 24481.0, "length": 210, "protein_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "gene_name": "POLR2E", "organism": "Bovine", "refseq_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "refseq_ac": "NP_001033182", "gene_names_uniprotkb": "POLR2E", "gene_names_refseq": "POLR2E", "protein_names_uniprotkb": "DNA-directed RNA polymerases I, II, and III subunit RPABC1; DNA-directed RNA polymerase II subunit E; RNA polymerases I, II, and III subunit ABC1; RPB5 homolog", "protein_names_refseq": "DNA-directed RNA polymerase II subunit E; DNA-directed RNA polymerases I, II, and III subunit RPABC1; RNA polymerase II subunit E; RNA polymerases I, II, and III subunit ABC1; RPB5 homolog; polymerase (RNA) II (DNA directed) polypeptide E, 25kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:512971)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16769904;26789250;28892040", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPABC1 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005665 RNA polymerase II, core complex;GO:0005736 RNA polymerase I complex;GO:0005666 RNA polymerase III complex", "go_biological_process": "GO:0042797 tRNA transcription by RNA polymerase III;GO:0006366 transcription by RNA polymerase II;GO:0006362 transcription elongation by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q2T9T3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TRY0-1", "uniprot_id": "FKBP4_BOVIN", "mass": 51529.0, "length": 459, "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP4", "gene_name": "FKBP4", "organism": "Bovine", "refseq_name": "peptidyl-prolyl cis-trans isomerase FKBP4", "refseq_ac": "NP_001029494", "gene_names_uniprotkb": "FKBP4", "gene_names_refseq": "FKBP-4; FKBP-52; FKBP4", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase FKBP4; 5.2.1.8; 52 kDa FK506-binding protein; 52 kDa FKBP; FK506-binding protein 4; FKBP-4; FKBP-52; HBI; HSP-binding immunophilin; Immunophilin FKBP52; PPIase FKBP4; Rotamase", "protein_names_refseq": "52 kDa FK506-binding protein; 52 kDa FKBP; FK506 binding protein 4, 59kDa; FK506-binding protein 4; FKBP52 protein; FKBP59; HBI; HSP-binding immunophilin; PPIase FKBP4; immunophilin FKBP52; p59 protein; peptidyl-prolyl cis-trans isomerase FKBP4; rotamase", "tax_id": 9913, "disease": "", "pathway": " (bta:508535)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "1279700;1371107;16305752", "class_list": "", "function": "Immunophilin protein with PPIase and co-chaperone activities (By similarity). Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) (By similarity). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments (By similarity). The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening (By similarity). Also acts as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5D9B2;Q3T0C4;Q9TRX9", "ec_number_list": "5.2.1.8", "go_molecular_function": "GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005874 microtubule;GO:0044295 axonal growth cone", "go_biological_process": "GO:0031111 negative regulation of microtubule polymerization or depolymerization;GO:0010977 negative regulation of neuron projection development;GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9TRY0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T847-1", "uniprot_id": "A0A140T847_BOVIN", "mass": 40424.0, "length": 362, "protein_name": "Protein Wnt", "gene_name": "WNT16", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "WNT16", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein Wnt", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3238698)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ligand for members of the frizzled family of seven transmembrane receptors., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005109 frizzled binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0046330 positive regulation of JNK cascade;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0030216 keratinocyte differentiation;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T847-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T851-1", "uniprot_id": "A0A140T851_BOVIN", "mass": 58919.0, "length": 527, "protein_name": "Vitamin K-dependent protein C", "gene_name": "PROC", "organism": "Bovine", "refseq_name": "vitamin K-dependent protein C isoform X1", "refseq_ac": "XP_024854240", "gene_names_uniprotkb": "PROC", "gene_names_refseq": "PROC", "protein_names_uniprotkb": "Vitamin K-dependent protein C; 3.4.21.69; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV", "protein_names_refseq": "vitamin K-dependent protein C isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:281428); (R-BTA-159740); (R-BTA-159763); (R-BTA-159782); (R-BTA-202733); (R-BTA-381426); (R-BTA-8957275); (R-BTA-9769733); (R-BTA-9769739); (R-BTA-9769743)", "pathway_count": 10, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.21.69;2.3.2.13;1.11.1.27;1.16.3.1;1.11.1.9;1.16.3.4;3.2.1.51;5.3.4.1;3.1.1.4;3.1.1.3;2.4.1.145;3.4.21.5;4.1.1.90;3.4.24.81;3.4.21.-;3.6.4.-", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0007596 blood coagulation;GO:0050819 negative regulation of coagulation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T851-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T861-1", "uniprot_id": "A0A140T861_BOVIN", "mass": 52382.0, "length": 514, "protein_name": "RNA-binding protein FUS", "gene_name": "FUS", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FUS", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA-binding protein FUS", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-72163); (R-BTA-72203); (R-BTA-9770562)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. Binds to nascent pre-mRNAs and acts as a molecular mediator between RNA polymerase II and U1 small nuclear ribonucleoprotein thereby coupling transcription and splicing. Also binds its own pre-mRNA and autoregulates its expression; this autoregulation mechanism is mediated by non-sense-mediated decay. Plays a role in DNA repair mechanisms by promoting D-loop formation and homologous recombination during DNA double-strand break repair. In neuronal cells, plays crucial roles in dendritic spine formation and stability, RNA transport, mRNA stability and synaptic homeostasis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0099523 presynaptic cytosol", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0051260 protein homooligomerization;GO:1990000 amyloid fibril formation;GO:0008380 RNA splicing;GO:0043484 regulation of RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T861-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T866-1", "uniprot_id": "A0A140T866_BOVIN", "mass": 64642.0, "length": 607, "protein_name": "D-3-phosphoglycerate dehydrogenase", "gene_name": "PHGDH", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PHGDH", "gene_names_refseq": "", "protein_names_uniprotkb": "D-3-phosphoglycerate dehydrogenase; 1.1.1.95", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-977347)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.95;1.1.1.399;1.1.1.37", "go_molecular_function": "GO:0051287 NAD binding;GO:0004617 phosphoglycerate dehydrogenase activity", "go_cellular_component": "", "go_biological_process": "GO:0006564 L-serine biosynthetic process;GO:0008652 amino acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T866-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T876-1", "uniprot_id": "A0A140T876_BOVIN", "mass": 33431.0, "length": 291, "protein_name": "Protein RER1", "gene_name": "RER1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RER1", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein RER1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0033130 acetylcholine receptor binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0009986 cell surface;GO:0005801 cis-Golgi network;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment", "go_biological_process": "GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006621 protein retention in ER lumen", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T876-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T879-1", "uniprot_id": "A0A140T879_BOVIN", "mass": 51668.0, "length": 465, "protein_name": "Chromogranin-A", "gene_name": "CHGA", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CHGA", "gene_names_refseq": "", "protein_names_uniprotkb": "Chromogranin-A", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Strongly inhibits glucose induced insulin release from the pancreas., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0098992 neuronal dense core vesicle;GO:0005576 extracellular region;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0043303 mast cell degranulation;GO:0002551 mast cell chemotaxis;GO:0033604 negative regulation of catecholamine secretion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T879-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T886-1", "uniprot_id": "A0A140T886_BOVIN", "mass": 97400.0, "length": 874, "protein_name": "Coatomer subunit gamma", "gene_name": "COPG1", "organism": "Bovine", "refseq_name": "coatomer subunit gamma-1", "refseq_ac": "NP_001032904", "gene_names_uniprotkb": "COPG1", "gene_names_refseq": "COPG1; COPG2; COPG", "protein_names_uniprotkb": "Coatomer subunit gamma", "protein_names_refseq": "coat protein gamma-cop; coatomer protein complex subunit gamma 1; coatomer protein complex, subunit gamma 2; coatomer subunit gamma-1; coatomer subunit gamma; gamma-1-COP; gamma-1-coat protein; gamma-coat protein", "tax_id": 9913, "disease": "", "pathway": " (bta:338055); (R-BTA-6807878); (R-BTA-6811434)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment;GO:0030126 COPI vesicle coat", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0009306 protein secretion;GO:0072384 organelle transport along microtubule;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T886-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LG56-1", "uniprot_id": "A0A3Q1LG56_BOVIN", "mass": 250944.0, "length": 2177, "protein_name": "Unconventional myosin-VIIa", "gene_name": "MYO7A", "organism": "Bovine", "refseq_name": "unconventional myosin-VIIa isoform X2", "refseq_ac": "XP_015330315", "gene_names_uniprotkb": "MYO7A", "gene_names_refseq": "MYO7A", "protein_names_uniprotkb": "Unconventional myosin-VIIa", "protein_names_refseq": "unconventional myosin-VIIa isoform X2", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2453902)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0019904 protein domain specific binding;GO:0051015 actin filament binding;GO:0030507 spectrin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005938 cell cortex;GO:0015629 actin cytoskeleton;GO:0016020 membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0007601 visual perception;GO:0007040 lysosome organization;GO:0030048 actin filament-based movement", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LG56-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LJU7-1", "uniprot_id": "A0A3Q1LJU7_BOVIN", "mass": 48297.0, "length": 424, "protein_name": "Stress-activated protein kinase JNK", "gene_name": "MAPK9", "organism": "Bovine", "refseq_name": "mitogen-activated protein kinase 9 isoform X2", "refseq_ac": "XP_005208428", "gene_names_uniprotkb": "MAPK9", "gene_names_refseq": "JNK2; MAPK9", "protein_names_uniprotkb": "Stress-activated protein kinase JNK; 2.7.11.24", "protein_names_refseq": "mitogen-activated protein kinase 9 isoform X2", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2559580); (R-BTA-2871796); (R-BTA-450321); (R-BTA-450341)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity;GO:0004705 JUN kinase activity;GO:0106310 protein serine kinase activity;GO:0004707 MAP kinase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0098685 Schaffer collateral - CA1 synapse;GO:0005634 nucleus", "go_biological_process": "GO:0010744 positive regulation of macrophage derived foam cell differentiation;GO:0031398 positive regulation of protein ubiquitination;GO:0042752 regulation of circadian rhythm;GO:0048511 rhythmic process;GO:0050804 modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LJU7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LVU8-1", "uniprot_id": "A0A3Q1LVU8_BOVIN", "mass": 78286.0, "length": 699, "protein_name": "Long-chain-fatty-acid--CoA ligase", "gene_name": "ACSL1", "organism": "Bovine", "refseq_name": "long-chain-fatty-acid--CoA ligase 1 isoform X1", "refseq_ac": "XP_010818563", "gene_names_uniprotkb": "ACSL1", "gene_names_refseq": "ACSL1; FACL2", "protein_names_uniprotkb": "Long-chain-fatty-acid--CoA ligase; 6.2.1.15; 6.2.1.3; Acyl-CoA synthetase; Long-chain acyl-CoA synthetase", "protein_names_refseq": "long-chain-fatty-acid--CoA ligase 1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2046105); (R-BTA-2046106); (R-BTA-75876)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.2.1.3;6.2.1.15;6.2.1.-;6.2.1.2;6.2.1.25", "go_molecular_function": "GO:0005524 ATP binding;GO:0047676 arachidonate-CoA ligase activity;GO:0043539 protein serine/threonine kinase activator activity;GO:0090433 palmitoyl-CoA ligase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005789 endoplasmic reticulum membrane;GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0044539 long-chain fatty acid import into cell;GO:0120162 positive regulation of cold-induced thermogenesis;GO:0000038 very long-chain fatty acid metabolic process;GO:0001676 long-chain fatty acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LVU8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LSX9-1", "uniprot_id": "FMNL2_BOVIN", "mass": 124214.0, "length": 1095, "protein_name": "Formin-like protein 2", "gene_name": "FMNL2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FMNL2", "gene_names_refseq": "", "protein_names_uniprotkb": "Formin-like protein 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:788312); (R-BTA-5663220); (R-BTA-9013106)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32017087", "class_list": "", "function": "Plays a role in actin cytoskeleton dynamics and regulation of cell shape., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0031267 small GTPase binding;GO:0003779 actin binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0016477 cell migration;GO:0008360 regulation of cell shape;GO:0030866 cortical actin cytoskeleton organization;GO:0030036 actin cytoskeleton organization;GO:0022604 regulation of cell morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A3Q1LSX9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LG16-1", "uniprot_id": "A0A3Q1LG16_BOVIN", "mass": 93694.0, "length": 836, "protein_name": "DNA replication licensing factor MCM4", "gene_name": "MCM4", "organism": "Bovine", "refseq_name": "DNA replication licensing factor MCM4 isoform X1", "refseq_ac": "XP_024857211", "gene_names_uniprotkb": "MCM4", "gene_names_refseq": "MCM4", "protein_names_uniprotkb": "DNA replication licensing factor MCM4; 3.6.4.12", "protein_names_refseq": "DNA replication licensing factor MCM4 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-176187); (R-BTA-68867); (R-BTA-68949); (R-BTA-68962); (R-BTA-69052)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;2.7.7.-;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53;2.7.11.22", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003678 DNA helicase activity;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0042555 MCM complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006270 DNA replication initiation;GO:0006271 DNA strand elongation involved in DNA replication;GO:1902975 mitotic DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LG16-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MKC7-1", "uniprot_id": "A0A3Q1MKC7_BOVIN", "mass": 55347.0, "length": 489, "protein_name": "calcium/calmodulin-dependent protein kinase", "gene_name": "CAMK2A", "organism": "Bovine", "refseq_name": "calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1", "refseq_ac": "XP_005209650", "gene_names_uniprotkb": "CAMK2A", "gene_names_refseq": "CAMK2A", "protein_names_uniprotkb": "calcium/calmodulin-dependent protein kinase; 2.7.11.17", "protein_names_refseq": "calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0033017 sarcoplasmic reticulum membrane;GO:0043197 dendritic spine;GO:0005954 calcium- and calmodulin-dependent protein kinase complex", "go_biological_process": "GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0060996 dendritic spine development;GO:0038166 angiotensin-activated signaling pathway;GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT;GO:0071346 cellular response to type II interferon", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MKC7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MDJ2-1", "uniprot_id": "A0A3Q1MDJ2_BOVIN", "mass": 53888.0, "length": 484, "protein_name": "Histone deacetylase 8", "gene_name": "HDAC8", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HDAC8", "gene_names_refseq": "", "protein_names_uniprotkb": "Histone deacetylase 8; 3.5.1.98; Protein deacetylase HDAC8; Protein decrotonylase HDAC8", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2467813); (R-BTA-2500257); (R-BTA-3214815); (R-BTA-350054)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility. In addition to protein deacetylase activity, also has protein-lysine deacylase activity: acts as a protein decrotonylase by mediating decrotonylation ((2E)-butenoyl) of histones., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.1.98;3.5.1.-", "go_molecular_function": "GO:0046872 metal ion binding;GO:0141221 histone deacetylase activity, hydrolytic mechanism;GO:0160008 protein decrotonylase activity;GO:0004407 histone deacetylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0000118 histone deacetylase complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MDJ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LJJ3-1", "uniprot_id": "A0A3Q1LJJ3_BOVIN", "mass": 55207.0, "length": 485, "protein_name": "ETS proto-onco 1, transcription factor", "gene_name": "ETS1", "organism": "Bovine", "refseq_name": "protein C-ets-1 isoform X1", "refseq_ac": "XP_005226882", "gene_names_uniprotkb": "ETS1", "gene_names_refseq": "ETS1", "protein_names_uniprotkb": "ETS proto-onco 1, transcription factor", "protein_names_refseq": "protein C-ets-1 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0043565 sequence-specific DNA binding;GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030578 PML body organization;GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LJJ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LK42-1", "uniprot_id": "A0A3Q1LK42_BOVIN", "mass": 47713.0, "length": 445, "protein_name": "peptidylprolyl isomerase", "gene_name": "FKBP8", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FKBP8", "gene_names_refseq": "", "protein_names_uniprotkb": "peptidylprolyl isomerase; 5.2.1.8", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:512356); (R-BTA-5689880)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.2.1.8;2.3.2.27;3.4.19.12;3.4.24.56;3.6.5.-;3.1.1.29", "go_molecular_function": "GO:0044183 protein folding chaperone;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005740 mitochondrial envelope;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0016020 membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process;GO:0006457 protein folding;GO:0060255 regulation of macromolecule metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LK42-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MHL3-1", "uniprot_id": "A0A3Q1MHL3_BOVIN", "mass": 72468.0, "length": 640, "protein_name": "LIM domain kinase 2", "gene_name": "LIMK2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LIMK2", "gene_names_refseq": "", "protein_names_uniprotkb": "LIM domain kinase 2; 2.7.11.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005819 spindle;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:1902018 negative regulation of cilium assembly;GO:0030036 actin cytoskeleton organization;GO:1900182 positive regulation of protein localization to nucleus;GO:0051650 establishment of vesicle localization;GO:0030953 astral microtubule organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MHL3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M9M0-1", "uniprot_id": "A0A3Q1M9M0_BOVIN", "mass": 99494.0, "length": 901, "protein_name": "Catenin alpha-1", "gene_name": "CTNNA1; CTNNA2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CTNNA1; CTNNA2; CTNNA2", "gene_names_refseq": "", "protein_names_uniprotkb": "Catenin alpha-1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:527492); (R-BTA-418990); (R-BTA-5218920); (R-BTA-525793); (R-BTA-5626467); (R-BTA-9764561); (R-BTA-9766229); (R-BTA-9958810); (R-BTA-9958825)", "pathway_count": 9, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0005198 structural molecule activity;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0015629 actin cytoskeleton;GO:0030424 axon", "go_biological_process": "GO:0007155 cell adhesion;GO:0030154 cell differentiation;GO:0010975 regulation of neuron projection development;GO:2001222 regulation of neuron migration;GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M9M0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1ML07-1", "uniprot_id": "A0A3Q1ML07_BOVIN", "mass": 45303.0, "length": 391, "protein_name": "Lactosylceramide alpha-2,3-sialyltransferase", "gene_name": "ST3GAL5", "organism": "Bovine", "refseq_name": "lactosylceramide alpha-2,3-sialyltransferase isoform X1", "refseq_ac": "XP_005212803", "gene_names_uniprotkb": "ST3GAL5", "gene_names_refseq": "SIAT9; ST3GAL-V; ST3GAL5", "protein_names_uniprotkb": "Lactosylceramide alpha-2,3-sialyltransferase; 2.4.3.9; CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; Ganglioside GM3 synthase; ST3Gal V; Sialyltransferase 9", "protein_names_refseq": "lactosylceramide alpha-2,3-sialyltransferase isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-4085001); (R-BTA-9840309)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the non-reducing terminal galactose (Gal) of glycosphingolipids forming gangliosides (important molecules involved in the regulation of multiple cellular processes, including cell proliferation and differentiation, apoptosis, embryogenesis, development, and oncogenesis). Mainly involved in the biosynthesis of ganglioside GM3 but can also use different glycolipids as substrate acceptors such as D-galactosylceramide (GalCer), asialo-GM2 (GA2) and asialo-GM1 (GA1), although less preferentially than beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer (LacCer)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.3.9;2.4.3.6", "go_molecular_function": "GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0009101 glycoprotein biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1ML07-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MHZ2-1", "uniprot_id": "A0A3Q1MHZ2_BOVIN", "mass": 134588.0, "length": 1184, "protein_name": "Ubiquitin conjugation factor E4", "gene_name": "UBE4B", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "UBE4B", "gene_names_refseq": "", "protein_names_uniprotkb": "Ubiquitin conjugation factor E4; 2.3.2.27; RING-type E3 ubiquitin transferase E4", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. Also functions as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0034450 ubiquitin-ubiquitin ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MHZ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M6B0-1", "uniprot_id": "A0A3Q1M6B0_BOVIN", "mass": 51771.0, "length": 458, "protein_name": "Protein adenylyltransferase FICD", "gene_name": "FICD", "organism": "Bovine", "refseq_name": "protein adenylyltransferase FICD", "refseq_ac": "NP_001192455", "gene_names_uniprotkb": "FICD", "gene_names_refseq": "FICD", "protein_names_uniprotkb": "Protein adenylyltransferase FICD; 2.7.7.108; AMPylator FICD; De-AMPylase FICD; FIC domain-containing protein", "protein_names_refseq": "FIC domain containing; protein adenylyltransferase FICD", "tax_id": 9913, "disease": "", "pathway": " (bta:505923)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein that can both mediate the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (AMPylation), and the removal of the same modification from target proteins (de-AMPylation), depending on the context. The side chain of Glu-231 determines which of the two opposing activities (AMPylase or de-AMPylase) will take place. Acts as a key regulator of the ERN1/IRE1-mediated unfolded protein response (UPR) by mediating AMPylation or de-AMPylation of HSPA5/BiP. In unstressed cells, acts as an adenylyltransferase by mediating AMPylation of HSPA5/BiP at 'Thr-518', thereby inactivating it. In response to endoplasmic reticulum stress, acts as a phosphodiesterase by mediating removal of ATP (de-AMPylation) from HSPA5/BiP at 'Thr-518', leading to restore HSPA5/BiP activity. Although it is able to AMPylate RhoA, Rac and Cdc42 Rho GTPases in vitro, Rho GTPases do not constitute physiological substrates., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.7.108", "go_molecular_function": "GO:0044603 protein adenylylhydrolase activity;GO:0005524 ATP binding;GO:0030544 Hsp70 protein binding;GO:0070733 AMPylase activity;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:1903894 regulation of IRE1-mediated unfolded protein response;GO:0006986 response to unfolded protein;GO:0034976 response to endoplasmic reticulum stress;GO:0018117 protein adenylylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M6B0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M590-1", "uniprot_id": "A0A3Q1M590_BOVIN", "mass": 151510.0, "length": 1354, "protein_name": "Partitioning defective 3 homolog", "gene_name": "PARD3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PARD3", "gene_names_refseq": "", "protein_names_uniprotkb": "Partitioning defective 3 homolog; Atypical PKC isotype-specific-interacting protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2173791); (R-BTA-420029)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0005923 bicellular tight junction;GO:0005938 cell cortex", "go_biological_process": "GO:0051301 cell division;GO:0030154 cell differentiation;GO:0007163 establishment or maintenance of cell polarity;GO:0007155 cell adhesion;GO:0008104 intracellular protein localization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M590-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M200-1", "uniprot_id": "A0A3Q1M200_BOVIN", "mass": 57015.0, "length": 515, "protein_name": "NEDD8-activating enzyme E1 catalytic subunit", "gene_name": "UBA3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "UBA3", "gene_names_refseq": "", "protein_names_uniprotkb": "NEDD8-activating enzyme E1 catalytic subunit; 6.2.1.64", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0019781 NEDD8 activating enzyme activity;GO:0042802 identical protein binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0032991 protein-containing complex;GO:0005634 nucleus", "go_biological_process": "GO:0045116 protein neddylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M200-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MJG0-1", "uniprot_id": "A0A3Q1MJG0_BOVIN", "mass": 154807.0, "length": 1370, "protein_name": "Tyrosine-protein kinase receptor", "gene_name": "INSR", "organism": "Bovine", "refseq_name": "insulin receptor isoform X3", "refseq_ac": "XP_005208873", "gene_names_uniprotkb": "INSR", "gene_names_refseq": "INSR", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor; 2.7.10.1", "protein_names_refseq": "insulin receptor isoform X3", "tax_id": 9913, "disease": "", "pathway": " (bta:408017); (R-BTA-6811558); (R-BTA-74713); (R-BTA-74749); (R-BTA-74751); (R-BTA-74752); (R-BTA-77387)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.1;3.1.3.48;3.1.3.16;2.7.10.4", "go_molecular_function": "GO:0005009 insulin receptor activity;GO:0005524 ATP binding;GO:0043560 insulin receptor substrate binding;GO:0043548 phosphatidylinositol 3-kinase binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0005770 late endosome;GO:0030424 axon;GO:0005899 insulin receptor complex", "go_biological_process": "GO:0048731 system development;GO:0010557 positive regulation of macromolecule biosynthetic process;GO:0010906 regulation of glucose metabolic process;GO:0010468 regulation of gene expression;GO:0005979 regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MJG0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LT44-1", "uniprot_id": "A0A3Q1LT44_BOVIN", "mass": 93453.0, "length": 837, "protein_name": "Tyrosine-protein kinase receptor", "gene_name": "NTRK2", "organism": "Bovine", "refseq_name": "BDNF/NT-3 growth factors receptor isoform X1", "refseq_ac": "XP_010806431", "gene_names_uniprotkb": "NTRK2", "gene_names_refseq": "NTRK2; Trk-B; TrkB", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor; 2.7.10.1", "protein_names_refseq": "BDNF/NT-3 growth factors receptor isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1257604); (R-BTA-6811558); (R-BTA-9026527); (R-BTA-9028731)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.1;2.7.1.153;2.7.1.137;3.1.3.48;2.7.10.4;2.3.2.27;3.6.5.2", "go_molecular_function": "GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity;GO:0005030 neurotrophin receptor activity;GO:0060175 brain-derived neurotrophic factor receptor activity;GO:0002020 protease binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005769 early endosome;GO:0005829 cytosol;GO:0014069 postsynaptic density;GO:0030424 axon", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:1990416 cellular response to brain-derived neurotrophic factor stimulus;GO:0007612 learning", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LT44-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MKH0-1", "uniprot_id": "A0A3Q1MKH0_BOVIN", "mass": 44147.0, "length": 397, "protein_name": "P2X purinoceptor", "gene_name": "P2RX3", "organism": "Bovine", "refseq_name": "P2X purinoceptor 3", "refseq_ac": "XP_059731161", "gene_names_uniprotkb": "P2RX3", "gene_names_refseq": "P2RX3", "protein_names_uniprotkb": "P2X purinoceptor; P2X purinoceptor 3", "protein_names_refseq": "P2X purinoceptor 3", "tax_id": 9913, "disease": "", "pathway": " (bta:530468); (R-BTA-139853); (R-BTA-418346)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Extracellular ATP-activated non-selective cation channel. Plays particularly important role in sensory neurons where its activation is critical for gustatory, nociceptive responses, visceral reflexes and sensory hypersensitization., [UniProtKB, UniProtKB]; Receptor for ATP that acts as a ligand-gated ion channel., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;1.8.-.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0001614 purinergic nucleotide receptor activity;GO:0004931 extracellularly ATP-gated monoatomic cation channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0043235 receptor complex;GO:0098794 postsynapse;GO:0098686 hippocampal mossy fiber to CA3 synapse", "go_biological_process": "GO:0050804 modulation of chemical synaptic transmission;GO:0070207 protein homotrimerization;GO:0070588 calcium ion transmembrane transport;GO:0071318 cellular response to ATP;GO:0033198 response to ATP", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MKH0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T891-1", "uniprot_id": "A0A140T891_BOVIN", "mass": 57612.0, "length": 515, "protein_name": "Pantetheinase", "gene_name": "VNN1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "VNN1", "gene_names_refseq": "", "protein_names_uniprotkb": "Pantetheinase; 3.5.1.92; Pantetheine hydrolase; Vascular non-inflammatory molecule 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-163125); (R-BTA-199220); (R-BTA-6798695)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.1.92;7.6.2.1;3.1.3.1;3.6.5.2;3.2.1.25;2.4.2.31;3.4.16.2;3.1.3.5;3.1.3.2;3.1.3.48;3.4.11.9;3.2.2.6;3.1.4.50;2.5.1.18;2.4.1.-;2.4.1.275;2.4.1.22;2.4.1.38;2.4.1.90;3.9.1.1;3.2.1.20;3.4.23.-", "go_molecular_function": "GO:0017159 pantetheine hydrolase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "GO:0015939 pantothenate metabolic process;GO:0045087 innate immune response;GO:0033089 positive regulation of T cell differentiation in thymus;GO:0098609 cell-cell adhesion;GO:0002526 acute inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T891-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T894-1", "uniprot_id": "A0A140T894_BOVIN", "mass": 28082.0, "length": 246, "protein_name": "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta", "gene_name": "YWHAB", "organism": "Bovine", "refseq_name": "14-3-3 protein beta/alpha", "refseq_ac": "NP_777219", "gene_names_uniprotkb": "YWHAB", "gene_names_refseq": "YWHAB", "protein_names_uniprotkb": "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta", "protein_names_refseq": "14-3-3 protein beta/alpha; KCIP-1; protein kinase C inhibitor protein 1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide", "tax_id": 9913, "disease": "", "pathway": " (bta:286863); (R-BTA-111447); (R-BTA-165159); (R-BTA-170968); (R-BTA-2028269); (R-BTA-392517); (R-BTA-450385); (R-BTA-450513); (R-BTA-5625740); (R-BTA-5628897); (R-BTA-5673000); (R-BTA-5674135); (R-BTA-5675221); (R-BTA-75035); (R-BTA-9614399)", "pathway_count": 15, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019904 protein domain specific binding;GO:0042802 identical protein binding;GO:0042826 histone deacetylase binding;GO:0050815 phosphoserine residue binding;GO:0004860 protein kinase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045744 negative regulation of G protein-coupled receptor signaling pathway;GO:0008104 intracellular protein localization;GO:0042308 negative regulation of protein import into nucleus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T894-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T897-1", "uniprot_id": "A0A140T897_BOVIN", "mass": 69323.0, "length": 607, "protein_name": "Albumin", "gene_name": "ALB", "organism": "Bovine", "refseq_name": "albumin precursor", "refseq_ac": "NP_851335", "gene_names_uniprotkb": "ALB", "gene_names_refseq": "ALB", "protein_names_uniprotkb": "Albumin", "protein_names_refseq": "BSA; albumin precursor; serum albumin", "tax_id": 9913, "disease": "", "pathway": " (bta:280717); (R-BTA-114608); (R-BTA-159418); (R-BTA-189451); (R-BTA-189483); (R-BTA-2168880); (R-BTA-381426); (R-BTA-8957275); (R-BTA-8964058); (R-BTA-9707564); (R-BTA-9749641); (R-BTA-9757110); (R-BTA-9793528)", "pathway_count": 13, "publication_count": 4, "publication_id_list": "28753530;29126006;29871929;31699587", "class_list": "", "function": "Hese obtained results provide an in-depth understanding of the interaction of the acid azo dye AO10 with serum albumins., [RefSeq, PubMed]; High glucose concentrations inhibited megalin expression and megalin-mediated albumin endocytosis after 48 h of incubation., [RefSeq, PubMed]; The binding constant and quenching constant values suggest that tamoxifen dislodges neratinib from its serum albumin (SA)complex whereas neratinib doesn't affect the interaction between SA and tamoxifen., [RefSeq, PubMed]; The interaction of DRV with bovine serum albumin (BSA), a major carrier protein, has been studied under simulated physiological conditions (pH7.4) by multi-spectroscopic techniques in combination with molecular modeling., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0005504 fatty acid binding;GO:0015643 toxic substance binding;GO:0030170 pyridoxal phosphate binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0070062 extracellular exosome;GO:0032991 protein-containing complex", "go_biological_process": "GO:0031667 response to nutrient levels;GO:0051902 negative regulation of mitochondrial depolarization;GO:0072732 cellular response to calcium ion starvation;GO:0015723 bilirubin transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A140T897-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T8A5-1", "uniprot_id": "A0A140T8A5_BOVIN", "mass": 46759.0, "length": 414, "protein_name": "Isocitrate dehydrogenase [NADP]", "gene_name": "IDH1", "organism": "Bovine", "refseq_name": "isocitrate dehydrogenase [NADP] cytoplasmic", "refseq_ac": "NP_851355", "gene_names_uniprotkb": "IDH1", "gene_names_refseq": "IDH1; IDPc", "protein_names_uniprotkb": "Isocitrate dehydrogenase [NADP]; 1.1.1.42", "protein_names_refseq": "IDH; IDP; NADP(+)-specific ICDH; cytosolic NADP-isocitrate dehydrogenase; isocitrate dehydrogenase (NADP(+)) 1, cytosolic; isocitrate dehydrogenase 1 (NADP+), soluble; isocitrate dehydrogenase [NADP] cytoplasmic; oxalosuccinate decarboxylase", "tax_id": 9913, "disease": "", "pathway": " (bta:281235); (R-BTA-389542); (R-BTA-6798695); (R-BTA-9033241)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "16636309", "class_list": "", "function": "Data suggest that the expression of cytosolic NADP+-dependent isocitrate dehydrogenase in bovine mammary epithelium is modulated by regulators of differentiation including extracellular matrix and lactogenic hormones as well as metabolic effectors., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.42;2.5.1.18;2.3.1.42;2.7.1.1;5.3.3.21;2.7.11.24;2.3.2.27;2.3.1.137;2.3.1.7;3.2.1.23;2.4.2.1;5.2.1.8;4.1.2.13;3.6.1.6;3.4.21.-;1.1.3.15;1.1.1.35;4.2.1.17;5.3.3.8;1.4.3.3;1.5.3.13;1.3.1.38;3.1.6.14;3.6.4.13;1.1.1.205;2.7.1.11;3.4.19.9;2.7.11.22;2.7.11.23;2.3.2.26;2.4.1.25;3.2.1.33;3.5.1.3;4.2.99.18;5.6.2.4;3.6.4.12;3.4.23.5;1.13.11.34;1.13.11.12;6.2.1.3;2.3.1.176;2.3.1.16;2.3.1.155;4.1.2.63;1.14.13.39;3.1.2.2;3.1.2.27;3.1.2.1;3.1.2.11;3.1.2.3;3.1.2.5;3.1.3.48;3.6.4.6;1.16.3.1;1.11.1.6;3.4.18.1;3.4.22.1;3.6.4.10;3.4.22.27;3.4.24.35;3.6.5.-;3.1.1.47;5.3.2.1;5.3.3.12;3.2.1.17;3.4.19.1;2.7.1.35;2.4.1.1;3.5.1.23;3.5.1.-;3.4.24.56;3.4.22.52;4.1.3.4;1.5.3.1;1.5.3.7;2.3.3.8;3.4.21.53;5.4.2.11;5.4.2.4;3.3.2.6;3.4.11.4;1.3.3.6;3.4.21.46;2.7.4.6;2.7.13.3;4.1.2.4;5.3.1.9;5.1.3.-;3.6.1.-;2.4.2.7;4.2.1.24", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0042803 protein homodimerization activity;GO:0051287 NAD binding;GO:0004450 isocitrate dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005777 peroxisome;GO:0005782 peroxisomal matrix;GO:0005829 cytosol", "go_biological_process": "GO:0006739 NADP+ metabolic process;GO:0006099 tricarboxylic acid cycle;GO:0006102 isocitrate metabolic process;GO:0006103 2-oxoglutarate metabolic process;GO:0006740 NADPH regeneration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A140T8A5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A140T8A7-1", "uniprot_id": "A0A140T8A7_BOVIN", "mass": 41928.0, "length": 376, "protein_name": "Pseudouridylate synthase RPUSD4, mitochondrial", "gene_name": "RPUSD4", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RPUSD4", "gene_names_refseq": "", "protein_names_uniprotkb": "Pseudouridylate synthase RPUSD4, mitochondrial; RNA pseudouridylate synthase domain-containing protein 4", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA, controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. Acts on position 39 in mitochondrial tRNA(Phe). Also catalyzes pseudouridylation of mRNAs in nucleus: acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions. Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.4.99.25;5.4.99.12;5.4.99.-", "go_molecular_function": "GO:0000049 tRNA binding;GO:0009982 pseudouridine synthase activity;GO:1990400 mitochondrial ribosomal large subunit rRNA binding", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0035770 ribonucleoprotein granule", "go_biological_process": "GO:0000455 enzyme-directed rRNA pseudouridine synthesis;GO:1990481 mRNA pseudouridine synthesis;GO:0070131 positive regulation of mitochondrial translation;GO:0070902 mitochondrial tRNA pseudouridine synthesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A140T8A7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MBQ6-1", "uniprot_id": "A0A3Q1MBQ6_BOVIN", "mass": 46484.0, "length": 415, "protein_name": "Beta-1,4-galactosyltransferase", "gene_name": "B4GALT3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "B4GALT3", "gene_names_refseq": "", "protein_names_uniprotkb": "Beta-1,4-galactosyltransferase; 2.4.1.-; Beta-1,4-GalTase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.-;2.4.1.38;2.4.1.90;2.4.1.275;2.4.1.22", "go_molecular_function": "GO:0046872 metal ion binding;GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0003945 N-acetyllactosamine synthase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0005975 carbohydrate metabolic process;GO:0009101 glycoprotein biosynthetic process;GO:0006678 glucosylceramide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MBQ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M245-1", "uniprot_id": "A0A3Q1M245_BOVIN", "mass": 201153.0, "length": 1797, "protein_name": "Kinesin family member 13A", "gene_name": "KIF13A", "organism": "Bovine", "refseq_name": "kinesin-like protein KIF13A isoform X6", "refseq_ac": "XP_024839713", "gene_names_uniprotkb": "KIF13A", "gene_names_refseq": "KIF13A", "protein_names_uniprotkb": "Kinesin family member 13A", "protein_names_refseq": "kinesin-like protein KIF13A isoform X6", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005813 centrosome;GO:0005871 kinesin complex;GO:0010008 endosome membrane", "go_biological_process": "GO:0045184 establishment of protein localization;GO:0007018 microtubule-based movement;GO:0006886 intracellular protein transport;GO:0008333 endosome to lysosome transport;GO:0032438 melanosome organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M245-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LG95-1", "uniprot_id": "A0A3Q1LG95_BOVIN", "mass": 75584.0, "length": 659, "protein_name": "ATP-binding cassette sub-family D member 3", "gene_name": "ABCD3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ABCD3", "gene_names_refseq": "", "protein_names_uniprotkb": "ATP-binding cassette sub-family D member 3; 70 kDa peroxisomal membrane protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long-chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched-chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation. Has fatty acyl-CoA thioesterase and ATPase activities. Probably hydrolyzes fatty acyl-CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes. Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005324 long-chain fatty acid transmembrane transporter activity;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0047617 fatty acyl-CoA hydrolase activity;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005778 peroxisomal membrane;GO:0005782 peroxisomal matrix;GO:0016020 membrane", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0006699 bile acid biosynthetic process;GO:0042760 very long-chain fatty acid catabolic process;GO:0006633 fatty acid biosynthetic process;GO:0007031 peroxisome organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LG95-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LGC0-1", "uniprot_id": "A0A3Q1LGC0_BOVIN", "mass": 52813.0, "length": 472, "protein_name": "Cannabinoid receptor 1", "gene_name": "CNR1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CNR1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cannabinoid receptor 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-373076); (R-BTA-418594)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Signaling typically involves reduction in cyclic AMP., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0042802 identical protein binding;GO:0004949 cannabinoid receptor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0005737 cytoplasm;GO:0005741 mitochondrial outer membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0098921 retrograde trans-synaptic signaling by endocannabinoid;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0099509 regulation of presynaptic cytosolic calcium ion concentration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LGC0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LH95-1", "uniprot_id": "A0A3Q1LH95_BOVIN", "mass": 91585.0, "length": 800, "protein_name": "Mitogen-activated protein kinase kinase kinase 20", "gene_name": "MAP3K20", "organism": "Bovine", "refseq_name": "mitogen-activated protein kinase kinase kinase 20", "refseq_ac": "NP_001192422", "gene_names_uniprotkb": "MAP3K20", "gene_names_refseq": "MAP3K20; MRK; ZAK", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase 20; 2.7.11.25; Leucine zipper- and sterile alpha motif-containing kinase; MLK-like mitogen-activated protein triple kinase; Mitogen-activated protein kinase kinase kinase MLT; Mixed lineage kinase-related kinase; Sterile alpha motif- and leucine zipper-containing kinase AZK", "protein_names_refseq": "MLK-related kinase; mitogen-activated protein kinase kinase kinase 20; sterile alpha motif and leucine zipper containing kinase AZK", "tax_id": 9913, "disease": "", "pathway": " (bta:519251)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Isoform that lacks the C-terminal region that mediates ribosome-binding: does not act as a sensor of ribosome collisions in response to ribotoxic stress. May act as an antagonist of isoform ZAKalpha: interacts with isoform ZAKalpha, leading to decrease the expression of isoform ZAKalpha., [UniProtKB, UniProtKB]; Stress-activated component of a protein kinase signal transduction cascade that promotes programmed cell death in response to various stress, such as ribosomal stress, osmotic shock and ionizing radiation. Acts by catalyzing phosphorylation of MAP kinase kinases, leading to activation of the JNK (MAPK8/JNK1, MAPK9/JNK2 and/or MAPK10/JNK3) and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways. Activates JNK through phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7, and MAP kinase p38 gamma (MAPK12) via phosphorylation of MAP2K3/MKK3 and MAP2K6/MKK6. Involved in stress associated with adrenergic stimulation: contributes to cardiac decompensation during periods of acute cardiac stress. May be involved in regulation of S and G2 cell cycle checkpoint by mediating phosphorylation of CHEK2., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0030295 protein kinase activator activity;GO:0043022 ribosome binding;GO:0004709 MAP kinase kinase kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0071493 cellular response to UV-B;GO:0006954 inflammatory response;GO:0043065 positive regulation of apoptotic process;GO:0007254 JNK cascade;GO:0042733 embryonic digit morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LH95-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LRQ3-1", "uniprot_id": "A0A3Q1LRQ3_BOVIN", "mass": 138258.0, "length": 1216, "protein_name": "Receptor-type tyrosine-protein phosphatase O", "gene_name": "PTPRO", "organism": "Bovine", "refseq_name": "receptor-type tyrosine-protein phosphatase O isoform X1", "refseq_ac": "XP_002687817", "gene_names_uniprotkb": "PTPRO", "gene_names_refseq": "PTPRO", "protein_names_uniprotkb": "Receptor-type tyrosine-protein phosphatase O; 3.1.3.48; Glomerular epithelial protein 1; Protein tyrosine phosphatase U2", "protein_names_refseq": "receptor-type tyrosine-protein phosphatase O isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:541043)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Possesses tyrosine phosphatase activity. Plays a role in regulating the glomerular pressure/filtration rate relationship through an effect on podocyte structure and function., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity;GO:0042803 protein homodimerization activity;GO:0045296 cadherin binding;GO:0017147 Wnt-protein binding", "go_cellular_component": "GO:0016020 membrane;GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0043197 dendritic spine;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0032835 glomerulus development;GO:0036060 slit diaphragm assembly;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0003093 regulation of glomerular filtration;GO:0030032 lamellipodium assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LRQ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LHW5-1", "uniprot_id": "A0A3Q1LHW5_BOVIN", "mass": 150498.0, "length": 1366, "protein_name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "gene_name": "MTMR4", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MTMR4", "gene_names_refseq": "", "protein_names_uniprotkb": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase; 3.1.3.95; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0008270 zinc ion binding;GO:0004722 protein serine/threonine phosphatase activity;GO:0019903 protein phosphatase binding;GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0006661 phosphatidylinositol biosynthetic process;GO:0046856 phosphatidylinositol dephosphorylation;GO:0061952 midbody abscission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LHW5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LIA5-1", "uniprot_id": "A0A3Q1LIA5_BOVIN", "mass": 65906.0, "length": 579, "protein_name": "Thromboxane-A synthase", "gene_name": "TBXAS1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TBXAS1", "gene_names_refseq": "", "protein_names_uniprotkb": "Thromboxane-A synthase; 4.2.1.152; 5.3.99.5; Cytochrome P450 5A1; Hydroperoxy icosatetraenoate dehydratase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-211979); (R-BTA-2162123)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation. Also cleaves PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2. Additionally, displays dehydratase activity, toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.2.1.152;5.3.99.5;1.14.14.1;1.14.99.1;5.3.99.4;5.3.99.3", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0004796 thromboxane-A synthase activity", "go_cellular_component": "GO:0005788 endoplasmic reticulum lumen;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0001516 prostaglandin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LIA5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MIT1-1", "uniprot_id": "A0A3Q1MIT1_BOVIN", "mass": 68662.0, "length": 629, "protein_name": "YTH domain-containing family protein", "gene_name": "YTHDF3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "YTHDF3", "gene_names_refseq": "", "protein_names_uniprotkb": "YTH domain-containing family protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:519708)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:1990247 N6-methyladenosine-containing RNA reader activity;GO:0043022 ribosome binding", "go_cellular_component": "GO:0000932 P-body;GO:0010494 cytoplasmic stress granule;GO:0005737 cytoplasm", "go_biological_process": "GO:0061157 mRNA destabilization;GO:0034063 stress granule assembly;GO:0045948 positive regulation of translational initiation;GO:0060339 negative regulation of type I interferon-mediated signaling pathway;GO:1901163 regulation of trophoblast cell migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MIT1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LJG6-1", "uniprot_id": "A0A3Q1LJG6_BOVIN", "mass": 147856.0, "length": 1342, "protein_name": "aldehyde oxidase", "gene_name": "AOX1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AOX1", "gene_names_refseq": "", "protein_names_uniprotkb": "aldehyde oxidase; 1.2.3.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-964975)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.2.3.1;1.17.3.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0042803 protein homodimerization activity;GO:0071949 FAD binding;GO:0004031 aldehyde oxidase activity;GO:0051287 NAD binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006805 xenobiotic metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LJG6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LJS3-1", "uniprot_id": "A0A3Q1LJS3_BOVIN", "mass": 98261.0, "length": 915, "protein_name": "ADAM metallopeptidase domain 15", "gene_name": "ADAM15", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ADAM15", "gene_names_refseq": "", "protein_names_uniprotkb": "ADAM metallopeptidase domain 15", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1474228)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0034987 immunoglobulin receptor binding;GO:0004222 metalloendopeptidase activity;GO:0005178 integrin binding;GO:0017124 SH3 domain binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0070062 extracellular exosome;GO:0012505 endomembrane system;GO:0016020 membrane", "go_biological_process": "GO:0002418 immune response to tumor cell;GO:0006508 proteolysis;GO:0007229 integrin-mediated signaling pathway;GO:0045087 innate immune response;GO:0030336 negative regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LJS3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LK79-1", "uniprot_id": "A0A3Q1LK79_BOVIN", "mass": 89666.0, "length": 801, "protein_name": "Disintegrin and metalloproteinase domain-containing protein 1a-like", "gene_name": "LOC112442048", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC112442048", "gene_names_refseq": "", "protein_names_uniprotkb": "Disintegrin and metalloproteinase domain-containing protein 1a-like", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane;GO:1990913 sperm head plasma membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0007339 binding of sperm to zona pellucida;GO:0008584 male gonad development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LK79-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M9R1-1", "uniprot_id": "A0A3Q1M9R1_BOVIN", "mass": 30096.0, "length": 261, "protein_name": "Tafazzin family protein", "gene_name": "TAFAZZIN", "organism": "Bovine", "refseq_name": "tafazzin isoform X1", "refseq_ac": "XP_002699760", "gene_names_uniprotkb": "TAFAZZIN; TAZ", "gene_names_refseq": "TAFAZZIN", "protein_names_uniprotkb": "Tafazzin family protein", "protein_names_refseq": "tafazzin isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:515177)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acyltransferase which is required to remodel newly synthesized phospholipid cardiolipin, a key component of the mitochondrial inner membrane. Required for the initiation of mitophagy. Required to ensure progression of spermatocytes through meiosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity;GO:0016746 acyltransferase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005743 mitochondrial inner membrane;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0035965 cardiolipin acyl-chain remodeling;GO:0042407 cristae formation;GO:0006644 phospholipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M9R1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LKG2-1", "uniprot_id": "A0A3Q1LKG2_BOVIN", "mass": 35764.0, "length": 321, "protein_name": "Voltage-dependent calcium channel gamma-4 subunit", "gene_name": "CACNG4", "organism": "Bovine", "refseq_name": "voltage-dependent calcium channel gamma-4 subunit", "refseq_ac": "XP_002696273", "gene_names_uniprotkb": "CACNG4", "gene_names_refseq": "CACNG4", "protein_names_uniprotkb": "Voltage-dependent calcium channel gamma-4 subunit", "protein_names_refseq": "voltage-dependent calcium channel gamma-4 subunit", "tax_id": 9913, "disease": "", "pathway": " (bta:519331); (R-BTA-112308); (R-BTA-399719); (R-BTA-5576892); (R-BTA-5576893); (R-BTA-5682910)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005246 calcium channel regulator activity;GO:0005245 voltage-gated calcium channel activity;GO:0016247 channel regulator activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0032281 AMPA glutamate receptor complex;GO:1990454 L-type voltage-gated calcium channel complex;GO:0036477 somatodendritic compartment;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0051968 positive regulation of synaptic transmission, glutamatergic;GO:0019226 transmission of nerve impulse;GO:0098970 postsynaptic neurotransmitter receptor diffusion trapping", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LKG2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M6P2-1", "uniprot_id": "A0A3Q1M6P2_BOVIN", "mass": 303306.0, "length": 2770, "protein_name": "Thyroglobulin", "gene_name": "TG", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TG", "gene_names_refseq": "", "protein_names_uniprotkb": "Thyroglobulin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0042446 hormone biosynthetic process;GO:0030878 thyroid gland development;GO:0006590 thyroid hormone generation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M6P2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LQP3-1", "uniprot_id": "A0A3Q1LQP3_BOVIN", "mass": 103183.0, "length": 928, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "KSR1", "organism": "Bovine", "refseq_name": "kinase suppressor of Ras 1 isoform X3", "refseq_ac": "XP_010814098", "gene_names_uniprotkb": "KSR1", "gene_names_refseq": "KSR1", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "kinase suppressor of Ras 1 isoform X3", "tax_id": 9913, "disease": "", "pathway": " (bta:100138565); (R-BTA-5673000); (R-BTA-5674135); (R-BTA-5675221)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;3.6.5.2;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;3.1.3.16;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;3.6.4.-;2.7.10.4;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0004672 protein kinase activity;GO:0051087 protein-folding chaperone binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0007265 Ras protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LQP3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M2A3-1", "uniprot_id": "A0A3Q1M2A3_BOVIN", "mass": 145232.0, "length": 1286, "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase", "gene_name": "PPIP5K2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PPIP5K2", "gene_names_refseq": "", "protein_names_uniprotkb": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; 2.7.4.24", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1855167)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, 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9913, "disease": "", "pathway": " (R-BTA-141430); (R-BTA-141444); (R-BTA-159227); (R-BTA-159230); (R-BTA-159231); (R-BTA-159236); (R-BTA-1855170); (R-BTA-1855196); (R-BTA-1855229); (R-BTA-191859); (R-BTA-2467813); (R-BTA-2500257); (R-BTA-3108214); (R-BTA-3232142); (R-BTA-3301854); (R-BTA-3371453); (R-BTA-4085377); (R-BTA-4551638); (R-BTA-4570464); (R-BTA-4615885); (R-BTA-5663220); (R-BTA-9648025)", "pathway_count": 22, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, 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